MCID: PTY001
MIFTS: 42

Pityriasis Rosea malady

Skin category

Summaries for Pityriasis Rosea

Sources:
64Wikipedia, 33MalaCards
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Wikipedia:64 Pityriasis rosea (also known as pityriasis rosea Gibert) is a skin rash. It is benign but may inflict... more...

MalaCards: Pityriasis Rosea, also known as pityriasis circinata, is related to lichen planus and hepatitis c. An important gene associated with Pityriasis Rosea is HLA-DRB4 (major histocompatibility complex, class II, DR beta 4), and among its related pathways are Classical antibody-mediated complement activation and COPII (Coat Protein 2) Mediated Vesicle Transport. The drugs methdilazine and methdilazine hydrochloride and the compounds dr-10 and ecori have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, skin and myeloid.

Aliases & Classifications for Pityriasis Rosea

Sources:
8Disease Ontology, 61UMLS, 57SNOMED-CT, 40NCIt, 27ICD9CM, 35MeSH, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin


Aliases & Descriptions:

pityriasis rosea 8 61
pityriasis circinata 8


External Ids:

Disease Ontology8 DOID:8892
NCIt40 C26855
ICD9CM27 696.3
SNOMED-CT57 77252004, 156373006
MeSH35 D017515
ICD1025 L42

Related Diseases for Pityriasis Rosea

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Pityriasis Rosea:



Diseases related to pityriasis rosea

Clinical Features for Pityriasis Rosea

Drugs & Therapeutics for Pityriasis Rosea

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Pityriasis Rosea

Drug clinical trials:

Search ClinicalTrials for Pityriasis Rosea

Search NIH Clinical Center for Pityriasis Rosea

Search CenterWatch for Pityriasis Rosea

Inferred drug relations via UMLS61/NDF-RT41:

Genetic Tests for Pityriasis Rosea

Anatomical Context for Pityriasis Rosea

Sources:
33MalaCards
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MalaCards organs/tissues related to Pityriasis Rosea:

33
Bone marrow, Skin, Myeloid, T cells, B cells, Tongue

Animal Models for Pityriasis Rosea or affiliated genes

Sources:
28inGenious Targeting Laboratory
See all sources

Publications for Pityriasis Rosea

Sources:
51PubMed
See all sources

Articles related to Pityriasis Rosea:

(show top 50)    (show all 342)
idTitleAuthorsYear
1
Pityriasis rosea and activation of latent herpesvirus infections. (24355270)
2014
2
Polymorphic pityriasis rosea precipitating psoriasis. (23437430)
2013
3
Applicability of proposed diagnostic criteria of pityriasis rosea: results of a prospective case-control study in India. (24249894)
2013
4
Recurrent and persistent pityriasis rosea: an atypical case presentation. (24071786)
2013
5
Pityriasis rosea with erythema multiforme - like lesions: an observational analysis. (23723495)
2013
6
Coexistence of two atypical variants of pityriasis rosea: a case report and review of literature. (21906158)
2012
7
Oligo-lesional eruptions rapidly following a herald plaque: abortive pityriasis rosea. (21965867)
2011
8
Annular groin eruptions: pityriasis rosea of vidal. (21244385)
2011
9
The pityriasis rosea calendar: a 7 year review of seasonal variation, age and sex distribution. (20450028)
2010
10
Acral pityriasis rosea in an infant with palmoplantar lesions: A novel manifestation. (23130187)
2010
11
Treatments for pityriasis rosea. (19585058)
2009
12
Pityriasis rosea. (18297832)
2008
13
Oral erythromycin is ineffective in the treatment of pityriasis rosea. (18246696)
2008
14
Pityriasis rosea. (16948385)
2006
15
Correlation between HLA and pityriasis rosea susceptibility in Brazilian blacks. (16405603)
2006
16
Pityriasis rosea in pregnancy--specific diagnostic implications and management considerations. (15904457)
2005
17
Pityriasis rosea-like eruptions due to mustard oil application. (16394442)
2005
18
Avidity of antibodies to human herpesvirus 7 suggests primary infection in young adults with pityriasis rosea. (15482314)
2004
19
Pityriasis rosea--evidence for and against an infectious aetiology. (15188706)
2004
20
Atypical pityriasis rosea and Hodgkin's disease. (14678538)
2004
21
Human herpesvirus 6 and 7 DNA in peripheral blood leucocytes and plasma in patients with pityriasis rosea by polymerase chain reaction: a prospective case control study. (11720179)
2001
22
Is pityriasis rosea skin healthier than healthy skin? (10891000)
2000
23
Epidemiological study of human herpesvirus-6 and human herpesvirus-7 in pityriasis rosea. (11069458)
2000
24
A pityriasis rosea-like eruption secondary to bacillus Calmette-GuAcrin therapy for bladder cancer. (8804852)
1996
25
UVB phototherapy for pityriasis rosea: a bilateral comparison study. (7490372)
1995
26
Picture of the month. Pityriasis rosea. (1669676)
1991
27
Recurrent pityriasis rosea. New episodes every year for five years. A case report. (1969211)
1990
28
Purpuric vesicular eruption in a 7-year-old girl. Vesicular pityriasis rosea. (2241206)
1990
29
Light and electron microscopic studies of pityriasis rosea. (3596886)
1987
30
Pityriasis rosea (Gibert): abnormal distribution pattern of antigen presenting cells in situ. (2408415)
1985
31
Pityriasis rosea. (6525101)
1984
32
Recent upper respiratory tract infection and pityriasis rosea: a case-control study of 249 matched pairs. (6849825)
1983
33
Pityriasis rosea unilateralis. (6874191)
1983
34
Pityriasis rosea in Rochester, Minnesota, 1969 to 1978. (6980904)
1982
35
Pityriasis rosea in Nigerians. (7419321)
1980
36
Pityriasis rosea (Herald spot). (753853)
1977
37
Immunological studies of pityriasis rosea (Gibert). (16688920)
1977
38
Pityriasis rosea in pregnancy: a case report. (5705310)
1968
39
Pityriasis rosea 1964-65. (5724108)
1968
40
Pityriasis rosea in a 4-month-old infant; an account of suggested contagiousness. (13983134)
1963
41
Pityriasis rosea. An etiologic study. (13786763)
1961
42
Pityriasis rosea in a three month old infant. (13717131)
1960
43
Psoriasis, seborrheic dermatitis and pityriasis rosea. (13224561)
1955
44
Pityriasis rosea accompanied with Bell's palsy. (15398750)
1950
45
Pityriasis rosea resembling secondary syphilis. (20983406)
1946
46
Pityriasis rosea (tinea versicolor?) with leukoderma. (20983399)
1946
47
Pityriasis Rosea (? Modified by Injections of Gold). (19990253)
1935
48
Pityriasis Rosea. (19978634)
1915
49
Discussion on Pityriasis Rosea. (19977613)
1914
50
Discussion on Pityriasis Rosea. (19977601)
1914

Genetic Variations for Pityriasis Rosea

Expression for genes affiliated with Pityriasis Rosea

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Pityriasis Rosea

Search GEO for disease gene expression data for Pityriasis Rosea.

Pathways for genes affiliated with Pityriasis Rosea

Sources:
54Reactome, 30KEGG, 12EMD Millipore, 56SinoBiological, 52QIAGEN
See all sources

Pathways related to Pityriasis Rosea according to GeneCards/GeneDecks:

(show all 37)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.3HLA-A, HLA-B, HLA-C
2
Hide members
9.3HLA-A, HLA-B, HLA-C
39.3HLA-A, HLA-B, HLA-C
49.3HLA-A, HLA-B, HLA-C
59.3HLA-C, HLA-B, HLA-A
69.3HLA-C, HLA-B, HLA-A
7
Hide members
9.2HLA-C, HLA-DQB1, HLA-DRB5, HLA-A
8
Immune response IFN alpha/beta signaling pathway
Hide members
9.0IFNA2, HLA-C, HLA-B, HLA-A
9
Hide members
9.0IFNA2, HLA-C, HLA-B, HLA-A
108.7HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5
118.4HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-DQB1
12
Hide members
8.4HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-DQB1
138.4HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-DQB1
14
Hide members
8.4HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-DQB1
15
Immune response NFAT in immune response
Hide members
8.4HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-DQB1
16
Hide members
8.4HLA-DQB1, HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
17
Hide members
8.4HLA-DQB1, HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
18
Hide members
8.4HLA-DQB1, HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
198.4HLA-DQB1, HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
20
Hide members
8.4HLA-DQB1, HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
21
Hide members
8.4HLA-DQB1, HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
228.4HLA-DQB1, HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
23
Immune response Antigen presentation by MHC class II
Hide members
8.4HLA-DQB1, HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
24
Hide members
8.4HLA-DQB1, HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
25
Hide members
8.4HLA-DQB1, HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
26
Immune response ICOS pathway in T-helper cell
Hide members
8.4HLA-DQB1, HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
278.4HLA-DQB1, HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
288.1IFNA2, HLA-DQB1, HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
297.2HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-B, HLA-DQB1
307.2HLA-C, HLA-DQB1, HLA-B, HLA-DRB5, HLA-DRB4, HLA-DRB3
317.2HLA-C, HLA-DQB1, HLA-B, HLA-DRB5, HLA-DRB4, HLA-DRB3
32
Hide members
7.2HLA-C, HLA-DQB1, HLA-B, HLA-DRB5, HLA-DRB4, HLA-DRB3
337.2HLA-C, HLA-DQB1, HLA-B, HLA-DRB5, HLA-DRB4, HLA-DRB3
34
Hide members
6.9IFNA2, HLA-C, HLA-DQB1, HLA-B, HLA-DRB5, HLA-DRB4
35
Hide members
6.9IFNA2, HLA-C, HLA-A, HLA-DRB1, HLA-DRB3, HLA-DRB4
36
Hide members
6.9HLA-A, IFNA2, HLA-C, HLA-DQB1, HLA-B, HLA-DRB5
37
Hide members
6.9IFNA2, HLA-C, HLA-DQB1, HLA-B, HLA-DRB5, HLA-DRB4

Compounds for genes affiliated with Pityriasis Rosea

Sources:
45Novoseek, 11DrugBank, 24HMDB
See all sources

Compounds related to Pityriasis Rosea according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1dr-10459.8HLA-A, HLA-DRB1
2ecori459.7HLA-B, HLA-DQB1
3busulfan45 1110.6IFNA2, HLA-B
4levamisole45 1110.5HLA-A, IFNA2
5ursodeoxycholic acid45 11 2411.4HLA-A, HLA-B, IFNA2

GO Terms for genes affiliated with Pityriasis Rosea

Sources:
16Gene Ontology
See all sources

Cellular components related to Pityriasis Rosea according to GeneCards/GeneDecks:

(show all 16)
idNameGO IDScoreTop Affiliating Genes
1MHC class I protein complexGO:0426129.5HLA-A, HLA-B, HLA-C
2early endosome membraneGO:0319019.3HLA-A, HLA-B, HLA-C
3phagocytic vesicle membraneGO:0306709.2HLA-C, HLA-B, HLA-A
4late endosome membraneGO:0319028.8HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
5external side of plasma membraneGO:0098978.7HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
6MHC class II protein complexGO:0426138.7HLA-DQB1, HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
7clathrin-coated endocytic vesicle membraneGO:0306698.7HLA-DQB1, HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
8transport vesicle membraneGO:0306588.6HLA-DQB1, HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
9trans-Golgi network membraneGO:0325888.6HLA-DQB1, HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
10endocytic vesicle membraneGO:0306668.6HLA-DQB1, HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
11lysosomal membraneGO:0057658.5HLA-DQB1, HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
12ER to Golgi transport vesicle membraneGO:0125077.5HLA-A, HLA-C, HLA-DQB1, HLA-B, HLA-DRB5, HLA-DRB4
13integral to lumenal side of endoplasmic reticulum membraneGO:0715567.5HLA-C, HLA-DQB1, HLA-B, HLA-DRB5, HLA-DRB4, HLA-DRB3
14integral to plasma membraneGO:0058877.5HLA-C, HLA-B, HLA-DRB4, HLA-DRB3, HLA-DRB1, HLA-A
15Golgi membraneGO:0001397.5HLA-C, HLA-DQB1, HLA-B, HLA-DRB5, HLA-DRB4, HLA-DRB3
16plasma membraneGO:0058866.2HLA-C, HLA-DQB1, HLA-B, HLA-DRB5, HLA-DRB4, HLA-DRB3

Biological processes related to Pityriasis Rosea according to GeneCards/GeneDecks:

(show all 24)
idNameGO IDScoreTop Affiliating Genes
1antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independentGO:0024809.4HLA-C, HLA-B, HLA-A
2positive regulation of T cell mediated cytotoxicityGO:0019169.4HLA-C, HLA-B, HLA-A
3antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependentGO:0024799.3HLA-A, HLA-B, HLA-C
4antigen processing and presentation of peptide antigen via MHC class IGO:0024749.3HLA-A, HLA-B, HLA-C
5antigen processing and presentation of exogenous peptide antigen via MHC class IGO:0425909.2HLA-C, HLA-B, HLA-A
6type I interferon-mediated signaling pathwayGO:0603379.1HLA-A, HLA-B, HLA-C, IFNA2
7regulation of interleukin-10 secretionGO:20011799.0HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
8regulation of interleukin-4 productionGO:0326739.0HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
9regulation of immune responseGO:0507769.0HLA-A, HLA-B, HLA-C
10T-helper 1 type immune responseGO:0420889.0HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
11inflammatory response to antigenic stimulusGO:0024379.0HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
12positive regulation of insulin secretion involved in cellular response to glucose stimulusGO:0357749.0HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5
13negative regulation of interferon-gamma productionGO:0326898.9HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5
14negative regulation of T cell proliferationGO:0421308.9HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
15protein tetramerizationGO:0512628.9HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5
16immunoglobulin production involved in immunoglobulin mediated immune responseGO:0023818.7HLA-DQB1, HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
17humoral immune response mediated by circulating immunoglobulinGO:0024558.7HLA-DQB1, HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
18T cell costimulationGO:0312958.7HLA-DQB1, HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
19T cell receptor signaling pathwayGO:0508528.6HLA-DQB1, HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
20antigen processing and presentation of exogenous peptide antigen via MHC class IIGO:0198868.6HLA-DQB1, HLA-DRB5, HLA-DRB4, HLA-DRB3, HLA-DRB1
21detection of bacteriumGO:0160458.2HLA-A, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-B
22interferon-gamma-mediated signaling pathwayGO:0603337.6HLA-DRB5, HLA-B, HLA-DQB1, HLA-C, HLA-DRB4, HLA-DRB3
23immune responseGO:0069557.0HLA-C, HLA-DQB1, HLA-B, HLA-DRB5, HLA-DRB4, HLA-DRB3
24cytokine-mediated signaling pathwayGO:0192216.7CX3CL1, HLA-A, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5

Molecular functions related to Pityriasis Rosea according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1receptor bindingGO:0051028.8CX3CL1, HLA-A, HLA-B, HLA-C
2MHC class II receptor activityGO:0323958.4HLA-DQB1, HLA-DRB4, HLA-DRB3, HLA-DRB1
3peptide antigen bindingGO:0426057.4HLA-A, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-B

Products for genes affiliated with Pityriasis Rosea

  • Antibodies
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Sources for Pityriasis Rosea

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet