MCID: PLC006
MIFTS: 24

Placental Choriocarcinoma malady

Cancer diseases category

Summaries for Placental Choriocarcinoma

About this section
Sources:
34MalaCards
See all sources

Fully expand this MalaCard

Download this MalaCard
MalaCards: Placental Choriocarcinoma, also known as choriocarcinoma of the placenta, is related to choriocarcinoma and cholera. An important gene associated with Placental Choriocarcinoma is MAFF (v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F), and among its related pathways are Tacrolimus/Cyclosporine Pathway, Pharmacodynamics and Glucose / Energy Metabolism. The compound glucose have been mentioned in the context of this disorder. Affiliated tissues include placenta, brain and breast.

Aliases & Classifications for Placental Choriocarcinoma

About this section
Sources:
9Disease Ontology, 63UMLS, 41NCIt
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

placental choriocarcinoma 9 63
choriocarcinoma of the placenta 9


External Ids:

Disease Ontology9 DOID:2024
NCIt41 C8893

Related Diseases for Placental Choriocarcinoma

About this section
Sources:
18GeneCards, 19GeneDecks
See all sources

Diseases related to Placental Choriocarcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1choriocarcinoma11.0
2cholera10.1
3breast cancer10.1
4fibrosarcoma10.1MAF

Symptoms for Placental Choriocarcinoma

About this section

Drugs & Therapeutics for Placental Choriocarcinoma

About this section
Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Placental Choriocarcinoma

Drug clinical trials:

Search ClinicalTrials for Placental Choriocarcinoma

Search NIH Clinical Center for Placental Choriocarcinoma

Search CenterWatch for Placental Choriocarcinoma

Genetic Tests for Placental Choriocarcinoma

About this section

Anatomical Context for Placental Choriocarcinoma

About this section
Sources:
34MalaCards
See all sources

MalaCards organs/tissues related to Placental Choriocarcinoma:

34
Placenta, Brain, Breast

Animal Models for Placental Choriocarcinoma or affiliated genes

About this section

Publications for Placental Choriocarcinoma

About this section
Sources:
53PubMed
See all sources

Articles related to Placental Choriocarcinoma:

(show all 46)
idTitleAuthorsYear
1
The impact of TGF-I^1 on the mRNA expression of TI^R I, TI^R II, Smad4 and the invasiveness of the JEG-3 placental choriocarcinoma cell line. (23205135)
2012
2
Phosphorylation of JAK2 by serotonin 5-HT (2A) receptor activates both STAT3 and ERK1/2 pathways and increases growth of JEG-3 human placental choriocarcinoma cell. (21993263)
2011
3
Expression of membrane and nuclear progesterone receptors in two human placental choriocarcinoma cell lines (JEG-3 and BeWo): Effects of syncytialization. (21455559)
2011
4
Genistein inhibits placental choriocarcinoma cell line JAR invasion through ERI^/MTA3/Snail/E-cadherin pathway. (22866146)
2011
5
Incidental finding of placental choriocarcinoma after an uncomplicated term pregnancy: a case report with review of the literature. (20736774)
2010
6
Nitrofurantoin transport by placental choriocarcinoma JAr cells: involvement of BCRP, OATP2B1 and other MDR transporters. (19924425)
2010
7
Expression of mTOR and downstream signalling components in the JEG-3 and BeWo human placental choriocarcinoma cell lines. (19956903)
2010
8
Long-chain polyunsaturated fatty acid transport across human placental choriocarcinoma (BeWo) cells. (19010540)
2009
9
Long-chain polyunsaturated fatty acids stimulate cellular fatty acid uptake in human placental choriocarcinoma (BeWo) cells. (19880178)
2009
10
Progesterone receptor (PR) isoforms PRA and PRB differentially regulate expression of the breast cancer resistance protein in human placental choriocarcinoma BeWo cells. (18042733)
2008
11
Incidental placental choriocarcinoma in a term pregnancy: a case report. (18922186)
2008
12
Expression of melatoninergic receptors in human placental choriocarcinoma cell lines. (16632463)
2006
13
Induction of endogenous Nrf2/small maf heterodimers by arsenic-mediated stress in placental choriocarcinoma cells. (16487037)
2006
14
Regulation of ADRP expression by long-chain polyunsaturated fatty acids in BeWo cells, a human placental choriocarcinoma cell line. (16391323)
2006
15
Dickkopf-1 induced apoptosis in human placental choriocarcinoma is independent of canonical Wnt signaling. (17026960)
2006
16
Comparison of folic acid uptake characteristics by human placental choriocarcinoma cells at acidic and physiological pH. (16900951)
2006
17
Insulin and leptin do not affect fatty acid uptake and metabolism in human placental choriocarcinoma (BeWo) cells. (15919610)
2005
18
Novel organic cation transporter 2-mediated carnitine uptake in placental choriocarcinoma (BeWo) cells. (15316089)
2005
19
Uptake of 1-methyl-4-phenylpyridinium (MPP+) by the JAR human placental choriocarcinoma cell line: comparison with 5-hydroxytryptamine. (12657510)
2003
20
Acyl-CoA thioesterase activity in human placental choriocarcinoma (BeWo), cells: effects of fatty acids. (12538089)
2003
21
Trialkyltin compounds enhance human CG secretion and aromatase activity in human placental choriocarcinoma cells. (12050258)
2002
22
Changes in expression and function of syncytin and its receptor, amino acid transport system B(0) (ASCT2), in human placental choriocarcinoma BeWo cells during syncytialization. (12175968)
2002
23
Uptake mechanism of valproic acid in human placental choriocarcinoma cell line (BeWo). (11334847)
2001
24
Transport mechanisms for vitamin C in the JAR human placental choriocarcinoma cell line. (9528682)
1998
25
Differential distribution and metabolism of arachidonic acid and docosahexaenoic acid by human placental choriocarcinoma (BeWo) cells. (9746226)
1998
26
Characterization of a sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin and lipoate in human placental choriocarcinoma cells. (9290147)
1997
27
Tyrosine phosphorylation-and epidermal growth factor-dependent regulation of the sodium-coupled amino acid transporter B0 in the human placental choriocarcinoma cell line JAR. (9194569)
1997
28
Uptake of long chain fatty acids by human placental choriocarcinoma (BeWo) cells: role of plasma membrane fatty acid-binding protein. (9458279)
1997
29
Benzo(a)pyrene, but not 2,3,7,8-tetrachlorodibenzo-p-dioxin, alters cell proliferation and c-myc and growth factor expression in human placental choriocarcinoma JEG-3 cells. (9070231)
1997
30
Cloning of the sodium-dependent, broad-scope, neutral amino acid transporter Bo from a human placental choriocarcinoma cell line. (8702519)
1996
31
Sodium-dependent carnitine transport in human placental choriocarcinoma cells. (8865821)
1996
32
JAR human placental choriocarcinoma cells actively synthesize, take up and release polyamines. (8888570)
1996
33
Substrate-specific regulation of the taurine transporter in human placental choriocarcinoma cells (JAR). (7756345)
1995
34
Induction of aromatase gene expression in human placental choriocarcinoma (JAR) cells by phorbol esters. (8193164)
1994
35
Calmodulin-dependent regulation of the catalytic function of the human serotonin transporter in placental choriocarcinoma cells. (8182048)
1994
36
Functional characterization of L-alanine transport in a placental choriocarcinoma cell line (BeWo). (7886021)
1994
37
Characterization of the glycine transport system GLYT 1 in human placental choriocarcinoma cells (JAR). (8075134)
1994
38
Functional coupling between a bafilomycin A1-sensitive proton pump and a probenecid-sensitive folate transporter in human placental choriocarcinoma cells. (8031869)
1994
39
Calmodulin-dependent modulation of pH sensitivity of the amino acid transport system L in human placental choriocarcinoma cells. (8018698)
1994
40
Regulation of the human serotonin transporter. Cholera toxin-induced stimulation of serotonin uptake in human placental choriocarcinoma cells is accompanied by increased serotonin transporter mRNA levels and serotonin transporter-specific ligand binding. (8408014)
1993
41
Modulation of the activity of amino acid transport system L by phorbol esters and calmodulin antagonists in a human placental choriocarcinoma cell line. (1324010)
1992
42
Transport of taurine and its regulation by protein kinase C in the JAR human placental choriocarcinoma cell line. (1854347)
1991
43
Expression and cyclic AMP-dependent regulation of a high affinity serotonin transporter in the human placental choriocarcinoma cell line (JAR). (1714897)
1991
44
Successful treatment of placental choriocarcinoma metastatic to brain followed by primary brain glioblastoma. (7060984)
1982
45
The prognostic application of HL-A and ABO typing in placental choriocarcinoma. (5377697)
1969
46
IMMUNOLOGICAL STUDIES IN PATIENTS WITH PLACENTAL CHORIOCARCINOMA. (14207839)
1964

Variations for Placental Choriocarcinoma

About this section

Expression for genes affiliated with Placental Choriocarcinoma

About this section
Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Placental Choriocarcinoma

Search GEO for disease gene expression data for Placental Choriocarcinoma.

Pathways for genes affiliated with Placental Choriocarcinoma

About this section
Sources:
51PathCards, 52PharmGKB, 5Cell Signaling Technology
See all sources

Pathways related to Placental Choriocarcinoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.6MAFF, MAF
29.3PLIN1, PGRMC1

Compounds for genes affiliated with Placental Choriocarcinoma

About this section
Sources:
46Novoseek
See all sources

Compounds related to Placental Choriocarcinoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1glucose468.9CGB, MAF, PLIN1

GO Terms for genes affiliated with Placental Choriocarcinoma

About this section
Sources:
17Gene Ontology
See all sources

Biological processes related to Placental Choriocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1transcription from RNA polymerase II promoterGO:0063669.6MAFF, MAF

Products for genes affiliated with Placental Choriocarcinoma

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Placental Choriocarcinoma

About this section
4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet