MCID: PLC006
MIFTS: 20

Placental Choriocarcinoma malady

Summaries for Placental Choriocarcinoma

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MalaCards based summary: Placental Choriocarcinoma, also known as choriocarcinoma of the placenta, is related to choriocarcinoma and fibrosarcoma. An important gene associated with Placental Choriocarcinoma is MAFF (v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F), and among its related pathways are Tacrolimus/Cyclosporine Pathway, Pharmacodynamics and Glucose / Energy Metabolism. The compound glucose have been mentioned in the context of this disorder. Affiliated tissues include placenta, brain and breast.

Aliases & Classifications for Placental Choriocarcinoma

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Placental Choriocarcinoma, Aliases & Descriptions:

Name: Placental Choriocarcinoma 9 60
 
Choriocarcinoma of the Placenta 9


External Ids:

Disease Ontology9 DOID:2024
NCIt38 C8893

Related Diseases for Placental Choriocarcinoma

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Diseases related to Placental Choriocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1choriocarcinoma11.0
2fibrosarcoma10.3MAF
3breast cancer10.1
4cholera10.1
5glioblastoma10.1
6chromosomal triplication9.9CGB, MAF

Graphical network of diseases related to Placental Choriocarcinoma:



Diseases related to placental choriocarcinoma

Symptoms for Placental Choriocarcinoma

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Drugs & Therapeutics for Placental Choriocarcinoma

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Drug clinical trials:

Search ClinicalTrials for Placental Choriocarcinoma

Search NIH Clinical Center for Placental Choriocarcinoma

Genetic Tests for Placental Choriocarcinoma

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Anatomical Context for Placental Choriocarcinoma

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MalaCards organs/tissues related to Placental Choriocarcinoma:

31
Placenta, Brain, Breast

Animal Models for Placental Choriocarcinoma or affiliated genes

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Publications for Placental Choriocarcinoma

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Articles related to Placental Choriocarcinoma:

(show all 49)
idTitleAuthorsYear
1
Activation of endocrine-related gene expression in placental choriocarcinoma cell lines following DNA methylation knock-down. (24623739)
2014
2
Role of protein kinase A in regulating steroid sulfate uptake for estrogen production in human placental choriocarcinoma cells. (24969759)
2014
3
The impact of TGF-I^1 on the mRNA expression of TI^R I, TI^R II, Smad4 and the invasiveness of the JEG-3 placental choriocarcinoma cell line. (23205135)
2012
4
Phosphorylation of JAK2 by serotonin 5-HT (2A) receptor activates both STAT3 and ERK1/2 pathways and increases growth of JEG-3 human placental choriocarcinoma cell. (21993263)
2011
5
Expression of membrane and nuclear progesterone receptors in two human placental choriocarcinoma cell lines (JEG-3 and BeWo): Effects of syncytialization. (21455559)
2011
6
Genistein inhibits placental choriocarcinoma cell line JAR invasion through ERI^/MTA3/Snail/E-cadherin pathway. (22866146)
2011
7
Incidental finding of placental choriocarcinoma after an uncomplicated term pregnancy: a case report with review of the literature. (20736774)
2010
8
Nitrofurantoin transport by placental choriocarcinoma JAr cells: involvement of BCRP, OATP2B1 and other MDR transporters. (19924425)
2010
9
Expression of mTOR and downstream signalling components in the JEG-3 and BeWo human placental choriocarcinoma cell lines. (19956903)
2010
10
Long-chain polyunsaturated fatty acid transport across human placental choriocarcinoma (BeWo) cells. (19010540)
2009
11
Long-chain polyunsaturated fatty acids stimulate cellular fatty acid uptake in human placental choriocarcinoma (BeWo) cells. (19880178)
2009
12
Progesterone receptor (PR) isoforms PRA and PRB differentially regulate expression of the breast cancer resistance protein in human placental choriocarcinoma BeWo cells. (18042733)
2008
13
Incidental placental choriocarcinoma in a term pregnancy: a case report. (18922186)
2008
14
Expression of melatoninergic receptors in human placental choriocarcinoma cell lines. (16632463)
2006
15
Induction of endogenous Nrf2/small maf heterodimers by arsenic-mediated stress in placental choriocarcinoma cells. (16487037)
2006
16
Regulation of ADRP expression by long-chain polyunsaturated fatty acids in BeWo cells, a human placental choriocarcinoma cell line. (16391323)
2006
17
Dickkopf-1 induced apoptosis in human placental choriocarcinoma is independent of canonical Wnt signaling. (17026960)
2006
18
Comparison of folic acid uptake characteristics by human placental choriocarcinoma cells at acidic and physiological pH. (16900951)
2006
19
Insulin and leptin do not affect fatty acid uptake and metabolism in human placental choriocarcinoma (BeWo) cells. (15919610)
2005
20
Novel organic cation transporter 2-mediated carnitine uptake in placental choriocarcinoma (BeWo) cells. (15316089)
2005
21
Uptake of 1-methyl-4-phenylpyridinium (MPP+) by the JAR human placental choriocarcinoma cell line: comparison with 5-hydroxytryptamine. (12657510)
2003
22
Acyl-CoA thioesterase activity in human placental choriocarcinoma (BeWo), cells: effects of fatty acids. (12538089)
2003
23
Arachidonic acid stimulates internalisation of leptin by human placental choriocarcinoma (BeWo) cells. (12445819)
2002
24
Trialkyltin compounds enhance human CG secretion and aromatase activity in human placental choriocarcinoma cells. (12050258)
2002
25
Changes in expression and function of syncytin and its receptor, amino acid transport system B(0) (ASCT2), in human placental choriocarcinoma BeWo cells during syncytialization. (12175968)
2002
26
Uptake mechanism of valproic acid in human placental choriocarcinoma cell line (BeWo). (11334847)
2001
27
Transport mechanisms for vitamin C in the JAR human placental choriocarcinoma cell line. (9528682)
1998
28
Differential distribution and metabolism of arachidonic acid and docosahexaenoic acid by human placental choriocarcinoma (BeWo) cells. (9746226)
1998
29
Characterization of a sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin and lipoate in human placental choriocarcinoma cells. (9290147)
1997
30
Tyrosine phosphorylation-and epidermal growth factor-dependent regulation of the sodium-coupled amino acid transporter B0 in the human placental choriocarcinoma cell line JAR. (9194569)
1997
31
Uptake of long chain fatty acids by human placental choriocarcinoma (BeWo) cells: role of plasma membrane fatty acid-binding protein. (9458279)
1997
32
Benzo(a)pyrene, but not 2,3,7,8-tetrachlorodibenzo-p-dioxin, alters cell proliferation and c-myc and growth factor expression in human placental choriocarcinoma JEG-3 cells. (9070231)
1997
33
Cloning of the sodium-dependent, broad-scope, neutral amino acid transporter Bo from a human placental choriocarcinoma cell line. (8702519)
1996
34
Sodium-dependent carnitine transport in human placental choriocarcinoma cells. (8865821)
1996
35
JAR human placental choriocarcinoma cells actively synthesize, take up and release polyamines. (8888570)
1996
36
Substrate-specific regulation of the taurine transporter in human placental choriocarcinoma cells (JAR). (7756345)
1995
37
Induction of aromatase gene expression in human placental choriocarcinoma (JAR) cells by phorbol esters. (8193164)
1994
38
Calmodulin-dependent regulation of the catalytic function of the human serotonin transporter in placental choriocarcinoma cells. (8182048)
1994
39
Functional characterization of L-alanine transport in a placental choriocarcinoma cell line (BeWo). (7886021)
1994
40
Characterization of the glycine transport system GLYT 1 in human placental choriocarcinoma cells (JAR). (8075134)
1994
41
Functional coupling between a bafilomycin A1-sensitive proton pump and a probenecid-sensitive folate transporter in human placental choriocarcinoma cells. (8031869)
1994
42
Calmodulin-dependent modulation of pH sensitivity of the amino acid transport system L in human placental choriocarcinoma cells. (8018698)
1994
43
Regulation of the human serotonin transporter. Cholera toxin-induced stimulation of serotonin uptake in human placental choriocarcinoma cells is accompanied by increased serotonin transporter mRNA levels and serotonin transporter-specific ligand binding. (8408014)
1993
44
Modulation of the activity of amino acid transport system L by phorbol esters and calmodulin antagonists in a human placental choriocarcinoma cell line. (1324010)
1992
45
Transport of taurine and its regulation by protein kinase C in the JAR human placental choriocarcinoma cell line. (1854347)
1991
46
Expression and cyclic AMP-dependent regulation of a high affinity serotonin transporter in the human placental choriocarcinoma cell line (JAR). (1714897)
1991
47
Successful treatment of placental choriocarcinoma metastatic to brain followed by primary brain glioblastoma. (7060984)
1982
48
The prognostic application of HL-A and ABO typing in placental choriocarcinoma. (5377697)
1969
49
IMMUNOLOGICAL STUDIES IN PATIENTS WITH PLACENTAL CHORIOCARCINOMA. (14207839)
1964

Variations for Placental Choriocarcinoma

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Expression for genes affiliated with Placental Choriocarcinoma

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Search GEO for disease gene expression data for Placental Choriocarcinoma.

Pathways for genes affiliated with Placental Choriocarcinoma

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Pathways related to Placental Choriocarcinoma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.6MAFF, MAF
29.3PLIN1, PGRMC1

Compounds for genes affiliated with Placental Choriocarcinoma

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Sources:
43Novoseek
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Compounds related to Placental Choriocarcinoma according to GeneCards Suite gene sharing:

idCompoundScoreTop Affiliating Genes
1glucose438.9CGB, MAF, PLIN1

GO Terms for genes affiliated with Placental Choriocarcinoma

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Biological processes related to Placental Choriocarcinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1transcription from RNA polymerase II promoterGO:00063669.6MAFF, MAF

Products for genes affiliated with Placental Choriocarcinoma

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Sources for Placental Choriocarcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet