MCID: PLG004
MIFTS: 43

Plagiocephaly malady

Category: Rare diseases

Aliases & Classifications for Plagiocephaly

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Summaries for Plagiocephaly

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Wikipedia:71 Plagiocephaly, also known as flat head syndrome, is a condition characterized by an asymmetrical... more...

MalaCards based summary: Plagiocephaly is related to muenke syndrome and isolated plagiocephaly. An important gene associated with Plagiocephaly is FGFR3 (Fibroblast Growth Factor Receptor 3), and among its related pathways are Endochondral Ossification and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include brain, bone and testes, and related mouse phenotypes are Decreased human cytomegalovirus (HCMV) strain AD169 replication and craniofacial.

Related Diseases for Plagiocephaly

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Diseases related to Plagiocephaly via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 54)
idRelated DiseaseScoreTop Affiliating Genes
1muenke syndrome31.4FGFR2, FGFR3
2isolated plagiocephaly12.0
3plagiocephaly and x-linked mental retardation11.8
4lambdoid synostosis11.2
5mental retardation, x-linked, with craniofacial dysmorphism10.9
6brachycephaly, deafness, cataract, microstomia, and mental retardation10.8
7hyde forster mccarthy berry syndrome10.8
8synostosis10.4
9craniosynostosis10.2
10antley-bixler syndrome without genital anomalies or disordered steroidogenesis10.1FGFR2, FGFR3
11cervical spinal canal and spinal cord meningioma10.1FGFR2, FGFR3
12aica-ribosiduria due to atic deficiency10.1FGFR2, FGFR3
13lingual-facial-buccal dyskinesia10.1FGFR2, FGFR3
14sp7-related osteogenesis imperfecta10.1FGFR2, FGFR3
15leg dermatosis10.1FGFR2, FGFR3
16pkp1-related ectodermal dysplasia/skin fragility syndrome10.1FGFR1, FGFR2
17pitx3-related anterior segment mesenchymal dysgenesis10.1FGFR1, FGFR2
18acrofacial dysostosis, palagonia type10.0FGFR1, FGFR2
19strabismus10.0
20t cell immunodeficiency primary10.0FGFR1, FGFR3
21epidemic typhus10.0FGFR1, FGFR2
22autosomal genetic disease10.0FGFR2, FGFR3
23hypoparathyroidism10.0FGFR2, FGFR3
24ovarian epithelial cancer10.0FGFR1, FGFR3
25early myoclonic encephalopathy10.0FGFR1, FGFR3
26cervicitis9.9
27familial porphyria cutanea tarda9.9FGFR1, FGFR2, FGFR3
28hartsfield syndrome9.9FGFR1, FGFR2, FGFR3
29osteoglophonic dysplasia9.9FGFR1, FGFR2, FGFR3
30crouzon syndrome with acanthosis nigricans9.9FGFR1, FGFR2, FGFR3
31apert syndrome9.9FGFR1, FGFR2, FGFR3
32thanatophoric dysplasia, type i9.9FGFR1, FGFR2, FGFR3
33saddan9.9FGFR1, FGFR2, FGFR3
34juvenile astrocytoma9.9FGFR1, FGFR3, TWIST1
35pancreatic cystadenoma9.8FGFR1, FGFR2
36scaphocephaly, maxillary retrusion, and mental retardation9.7FGFR1, FGFR2, FGFR3, TWIST1
37cervical cancer, somatic9.7FGFR1, FGFR2, FGFR3, TWIST1
38robinow-sorauf syndrome9.7FGFR1, FGFR2, FGFR3, TWIST1
39bone structure disease9.7FGFR1, FGFR2, FGFR3, TWIST1
40hypogonadotropic hypogonadism 2 with or without anosmia9.7FGFR1, FGFR2, FGFR3, TWIST1
41sudden infant death syndrome9.7
42crouzon syndrome9.7
43otitis media9.7
44hemifacial microsomia9.7
45hemangioma9.7
46scoliosis9.7
47astigmatism9.7
48dysostosis9.7
49refractive error9.7
50idiopathic recurrent and disabling cutaneous herpes9.6FGFR3, TCF12, TWIST1, ZIC1

Graphical network of the top 20 diseases related to Plagiocephaly:



Diseases related to plagiocephaly

Symptoms & Phenotypes for Plagiocephaly

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GenomeRNAi Phenotypes related to Plagiocephaly according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00248-A9.8FGFR1, FGFR2, FGFR3

MGI Mouse Phenotypes related to Plagiocephaly according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053829.3FGFR1, FGFR2, FGFR3, TWIST1
2MP:00053819.3FGFR1, FGFR2, FGFR3, TWIST1
3MP:00053719.3FGFR1, FGFR2, FGFR3, TWIST1
4MP:00053699.1FGFR1, FGFR2, TWIST1, ZIC1
5MP:00053868.0FGFR1, FGFR2, FGFR3, TCF12, TWIST1, ZIC1
6MP:00053788.0FGFR1, FGFR2, FGFR3, TCF12, TWIST1, ZIC1
7MP:00053907.9FGFR1, FGFR2, FGFR3, TWIST1, ZIC1
8MP:00107687.9FGFR1, FGFR2, FGFR3, TCF12, TWIST1, ZIC1
9MP:00036317.9FGFR1, FGFR2, FGFR3, TCF12, TWIST1, ZIC1

Drugs & Therapeutics for Plagiocephaly

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Drugs for Plagiocephaly (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Salicylic acidapproved, vet_approved18969-72-7338
Synonyms:
105910_ALDRICH
105910_SIAL
2 Hydroxybenzoic Acid
2-Carboxyphenol
2-Hydroxybenzenecarboxylate
2-Hydroxybenzenecarboxylic acid
2-Hydroxybenzoate
2-Hydroxybenzoic acid
2-hydroxy(1-14c)benzoic acid
247588_SIAL
27301_SIAL
69-72-7
7681-06-3
8052-31-1
84210_FLUKA
84210_SIAL
AB1002436
AC1L190M
AC1Q1HCK
AC1Q72IF
AI3-02407
AKOS000118979
ALPHA/BETA HYDROXY ACIDS (SALICYLIC ACID) (SEE ALPHA/BETA HYDROXY ACIDS)
AR-1E2203
ATA fraction 10, ammonium salt
Acid, 2-Hydroxybenzoic
Acid, Salicylic
Acid, o-Hydroxybenzoic
Acid, ortho-Hydroxybenzoic
Acido o-idrossibenzoico
Acido o-idrossibenzoico [Italian]
Acido salicilico
Acido salicilico [Italian]
Acidum salicylicum
Advanced Pain Relief Callus Removers
Advanced Pain Relief Corn Removers
Advanced pain relief callus removers
Advanced pain relief corn removers
Akurza Cream
Akurza Lotion
Alpha/Beta Hydroxy Acids (Glycolic Acid, Salicylic Acid)
BENZOIC ACID,2-HYDROXY SALICYLIC ACID
BIDD:ER0602
BRN 0774890
Benzoic acid, 2-hydroxy- (9CI)
C00805
CCRIS 6714
CHEBI:16914
CHEMBL424
CID338
CMC_13852
Caswell No. 731
Clear away Wart Remover
Clear away wart remover
Compound W
Compound w
D00097
D020156
DB00936
DHS Sal Shampoo
DivK1c_000301
Domerine
Dr. Scholl'S Callus Removers
Dr. Scholl'S Corn Removers
Dr. Scholl'S Wart Remover Kit
Dr. Scholl's callus removers
Dr. Scholl's corn removers
Dr. Scholl's wart remover kit
DuoPlant Gel
Duofil Wart Remover
Duofil wart remover
Duofilm
Duoplant
E9A559BE-383B-4F83-BC02-3031D03D558A
EINECS 200-712-3
EPA Pesticide Chemical Code 076602
Freezone
H0206
HSDB 672
Hydrisalic Gel
I04-0192
IDI1_000301
InChI=1/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10
Ionil
Ionil Plus
Ionil plus
Ionil-Plus
 
K 537
K 557
KBio1_000301
KBio2_001428
KBio2_003996
KBio2_006564
KBioSS_001428
Keralyt
Kyselina 2-hydroxybenzoova
Kyselina 2-hydroxybenzoova [Czech]
Kyselina salicylova
Kyselina salicylova [Czech]
LS-2169
MLS000069653
Mediplast pads
MolPort-001-769-476
NCGC00159447-02
NCGC00159447-04
NINDS_000301
NSC 180
NSC180
NSC629474
O-Carboxyphenol
O-Hydroxybenzoate
O-Hydroxybenzoic acid
O-carboxyphenol
O-hydroxybenzoic acid
Occlusal
Oprea1_040343
Orthohydroxybenzoic acid
P&S Shampoo
Phenol-2-carboxylate
Phenol-2-carboxylic acid
Propa pH Peel-Off Acne Mask
Psoriacid-S-Stift
Psoriacid-S-stift
Retarder SAX
Retarder W
Rutranex
S5922_SIGMA
S7401_SIGMA
S8519_SIGMA
SALICYLIC ACID (SEE ALSO ALPHA HYDROXY ACIDS)
SALICYLIC ACID, ACS
SAX
SBB052826
SGCUT00012
SMP2_000145
SMR000059163
STK258681
Salex Cream
Salex Lotion
Salicyclic acid
Salicylate
Salicylic acid
Salicylic acid & Sulfur Soap
Salicylic acid (6CI,8CI)
Salicylic acid (JP15/USP)
Salicylic acid (TN)
Salicylic acid Soap
Salicylic acid [USAN:JAN]
Salicylic acid collodion
Salicylic acid soap
Salicylic acid, tech
Salicylic acid, tech.
Salicylic acid-ring-UL-14C
Saligel
Salonil
Sebucare
Sebulex
Spectrum_000948
Stri-Dex
Trans-Ver-Sal
UNII-O414PZ4LPZ
UPCMLD-DP126
UPCMLD-DP126:001
Verrugon
W398500_ALDRICH
WLN: QVR BQ
bmse000252
o Hydroxybenzoic Acid
o-Carboxyphenol
o-hydroxybenzoic acid
ortho Hydroxybenzoic Acid
ortho-Hydroxybenzoic Acid
phenol derivative, 7
salicylate
salicylic acid
to_000004

Interventional clinical trials:

idNameStatusNCT IDPhase
1Postural Assessment in PlagiocephalyCompletedNCT01989286
2Investigating the Effectiveness of Mobilization on Congenital Muscular Torticollis and Deformational PlagiocephalyRecruitingNCT02403011
3Newborn Head Molding and Later AsymmetriesActive, not recruitingNCT02283229
4Brain Characteristics Noted Prior to and Following TreatmentActive, not recruitingNCT02392195
5Osteopathic Approach Into Neonatology Ward: the NE-O ModelAvailableNCT01902563
6Investigating the Effectiveness of Control Frequency on and Deformational PlagiocephalyNot yet recruitingNCT02607969
7Cranial Orthotic Device Versus Repositioning Techniques for the Management of Plagiocephaly: the CRANIO Randomized TrialNot yet recruitingNCT02370901
8Cranial Cup Use for the Prevention of Positional Head Shape Deformity in the NICUTerminatedNCT01218087
9Hanger Helmet StudyWithdrawnNCT02561728

Search NIH Clinical Center for Plagiocephaly

Genetic Tests for Plagiocephaly

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Genetic tests related to Plagiocephaly:

id Genetic test Affiliating Genes
1 Plagiocephaly27

Anatomical Context for Plagiocephaly

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MalaCards organs/tissues related to Plagiocephaly:

36
Brain, Bone, Testes, Eye, Heart

Publications for Plagiocephaly

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Articles related to Plagiocephaly:

(show top 50)    (show all 360)
idTitleAuthorsYear
1
The health belief model and factors associated with adherence to treatment recommendations for positional plagiocephaly. (28084919)
2017
2
Plagiocephaly and Developmental Delay: A Systematic Review. (28009719)
2017
3
Factors influencing outcomes of the treatment of positional plagiocephaly in infants: a 7-year experience. (28084921)
2017
4
Therapy effects of head orthoses in positional plagiocephaly. (27595189)
2016
5
Assessing the Cervical Range of Motion in Infants With Positional Plagiocephaly. (27192654)
2016
6
Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines for the Management of Patients With Positional Plagiocephaly: Executive Summary. (27759671)
2016
7
Guidelines: Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on the Role of Cranial Molding Orthosis (Helmet) Therapy for Patients With Positional Plagiocephaly. (27759675)
2016
8
Assessment of Deformational Plagiocephaly Severity and Neonatal Developmental Delay. (27557465)
2016
9
An Evidence-Based Approach to Nonsynostotic Plagiocephaly. (27673539)
2016
10
Plagiocephaly and Developmental Delay: The Expanding Role of the Craniofacial Surgeon. (27428923)
2016
11
Use of external orthotic helmet therapy in positional plagiocephaly. (26947339)
2016
12
Neurological assessment of Chinese infants with positional plagiocephaly using a Chinese version of the Infant Neurological International Battery (INFANIB). (27718070)
2016
13
Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on the Role of Cranial Molding Orthosis (Helmet) Therapy for Patients With Positional Plagiocephaly. (27776089)
2016
14
Evidence for Use of Frontozygomaticus and Contralateral Eurion as Hand-Caliper Landmarks for Assessment of Deformational Plagiocephaly. (27428906)
2016
15
Long-Term Assessment of Suturectomy in Trigonocephaly and Anterior Plagiocephaly. (27092924)
2016
16
Effect of fronto-orbital advancement on astigmatism in patients with anterior plagiocephaly. (27567360)
2016
17
Guidelines: Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline for the Management of Patients With Positional Plagiocephaly: The Role of Physical Therapy. (27759674)
2016
18
Sonographic Analysis of Changes in Skull Shape After Cranial Molding Helmet Therapy in Infants With Deformational Plagiocephaly. (26928929)
2016
19
Effects of manual therapy on treatment duration and motor development in infants with severe nonsynostotic plagiocephaly: a randomised controlled pilot study. (27465676)
2016
20
Diagnostic Yield of Routine Skull Radiographs in Infants With Deformational Plagiocephaly. (27136073)
2016
21
Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline for the Management of Patients With Positional Plagiocephaly: The Role of Physical Therapy. (27776088)
2016
22
Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline for the Diagnosis of Patients With Positional Plagiocephaly: The Role of Imaging. (27776086)
2016
23
Quantitative analysis of craniofacial dysmorphology in infants with anterior synostotic plagiocephaly. (27541866)
2016
24
Impact of severity and therapy onset on helmet therapy in positional plagiocephaly. (26724211)
2016
25
Plagiocephaly due to Frontosphenoidal Suture Synostosis: Report of 2 Cases and Literature Review. (26960206)
2016
26
Positional plagiocephaly reduces parental adherence to SIDS Guidelines and inundates the health system. (27504717)
2016
27
Assessment of Deformational Plagiocephaly Severity and Neonatal Developmental Delay. (28005729)
2016
28
Repercussions of plagiocephaly on posture, muscle flexibility and balance in children aged 3-5a88years old. (27329908)
2016
29
Guidelines: Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on the Management of Patients With Positional Plagiocephaly: The Role of Repositioning. (27759673)
2016
30
Malocclusion in the primary dentition in children with and without deformational plagiocephaly. (26795625)
2016
31
Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on the Management of Patients With Positional Plagiocephaly: The Role of Repositioning. (27776087)
2016
32
Guidelines: Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline for the Diagnosis of Patients With Positional Plagiocephaly: The Role of Imaging. (27759672)
2016
33
Positional plagiocephaly following ventriculoperitoneal shunting in neonates and infancy-how serious is it? (27848003)
2016
34
Systematic Review and Evidence-Based Guidelines for the Management of Patients with Positional Plagiocephaly. (27940801)
2016
35
Clinical assessment of head orientation profile development and its relationship with positional plagiocephaly in healthy term infants - A prospective study. (27031440)
2016
36
Frontal cranial modeling using endocranial resorbable plate fixation in 27 consecutive plagiocephaly and trigonocephaly patients. (25715840)
2015
37
Prevalence and Consequences of Positional Plagiocephaly and Brachycephaly. (26595002)
2015
38
Prevention of deformational plagiocephaly in hospitalized infants using a new orthotic device. (25573141)
2015
39
Three-dimensional analysis of cranial and facial asymmetry after helmet therapy for positional plagiocephaly. (25771922)
2015
40
Orthotic Management of Deformational Plagiocephaly: Consensus Clinical Standards of Care. (26247705)
2015
41
The usage of the three-dimension distractor in the NAVID system for plagiocephaly-three case reports. (26188775)
2015
42
Diagnostic Yield of Cervical Radiographs in Infants with Deformational Plagiocephaly. (26218395)
2015
43
Preventing deformational plagiocephaly through parent guidance: a randomized, controlled trial. (25823758)
2015
44
Efficacy of Conservative and Cranial Orthotic Therapy in Over 4000 Patients Treated for Positional Plagiocephaly Over a Five-Year Period. (26397486)
2015
45
Methods to Diagnose, Classify, and Monitor Infantile Deformational Plagiocephaly and Brachycephaly: A Narrative Review. (26778933)
2015
46
Lambdoid Synostosis Versus Positional Posterior Plagiocephaly, a Comparison of Skull Base and Shape of Calvarium Using Computed Tomography Imaging. (26335322)
2015
47
Comparison of Direct and Digital Measures of Cranial Vault Asymmetry for Assessment of Plagiocephaly. (26267578)
2015
48
Uvular Malformation in the Presence of Deformational Plagiocephaly. (25901668)
2015
49
The danger of posterior plagiocephaly. (25987949)
2015
50
Argenta Clinical Classification of Deformational Plagiocephaly. (25901672)
2015

Variations for Plagiocephaly

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Expression for genes affiliated with Plagiocephaly

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Search GEO for disease gene expression data for Plagiocephaly.

Pathways for genes affiliated with Plagiocephaly

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Pathways related to Plagiocephaly according to GeneCards Suite gene sharing:

(show all 29)
idSuper pathwaysScoreTop Affiliating Genes
19.4FGFR1, FGFR3
29.4FGFR1, FGFR3
39.4FGFR1, FGFR2
49.0FGFR1, FGFR2, FGFR3
5
Show member pathways
9.0FGFR1, FGFR2, FGFR3
69.0FGFR1, FGFR2, FGFR3
7
Show member pathways
9.0FGFR1, FGFR2, FGFR3
8
Show member pathways
9.0FGFR1, FGFR2, FGFR3
9
Show member pathways
9.0FGFR1, FGFR2, FGFR3
10
Show member pathways
9.0FGFR1, FGFR2, FGFR3
11
Show member pathways
9.0FGFR1, FGFR2, FGFR3
12
Show member pathways
9.0FGFR1, FGFR2, FGFR3
139.0FGFR1, FGFR2, FGFR3
14
Show member pathways
9.0FGFR1, FGFR2, FGFR3
159.0FGFR1, FGFR2, FGFR3
169.0FGFR1, FGFR2, FGFR3
17
Show member pathways
9.0FGFR1, FGFR2, FGFR3
189.0FGFR1, FGFR2, FGFR3
199.0FGFR1, FGFR2, FGFR3
20
Show member pathways
9.0FGFR1, FGFR2, FGFR3
21
Show member pathways
9.0FGFR1, FGFR2, FGFR3
22
Show member pathways
9.0FGFR1, FGFR2, FGFR3
23
Show member pathways
9.0FGFR1, FGFR2, FGFR3
24
Show member pathways
9.0FGFR1, FGFR2, FGFR3
25
Show member pathways
9.0FGFR1, FGFR2, FGFR3
26
Show member pathways
9.0FGFR1, FGFR2, FGFR3
27
Show member pathways
8.5FGFR1, FGFR2, FGFR3, TWIST1
28
Show member pathways
8.2FGFR1, FGFR2, FGFR3, TCF12
297.9FGFR1, FGFR2, FGFR3, TWIST1, ZIC1

GO Terms for genes affiliated with Plagiocephaly

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Biological processes related to Plagiocephaly according to GeneCards Suite gene sharing:

(show all 38)
idNameGO IDScoreTop Affiliating Genes
1bone mineralizationGO:003028210.4FGFR2, FGFR3
2bone morphogenesisGO:006034910.4FGFR2, FGFR3
3endochondral bone growthGO:000341610.4FGFR2, FGFR3
4bone developmentGO:006034810.3FGFR2, TWIST1
5embryonic cranial skeleton morphogenesisGO:004870110.3FGFR2, TWIST1
6odontogenesisGO:004247610.3FGFR2, TWIST1
7positive regulation of epithelial cell proliferationGO:005067910.2FGFR2, TWIST1
8chondrocyte differentiationGO:000206210.2FGFR1, FGFR3
9branching involved in salivary gland morphogenesisGO:006044510.2FGFR1, FGFR2
10fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex developmentGO:003560710.2FGFR1, FGFR2
11lung-associated mesenchyme developmentGO:006048410.2FGFR1, FGFR2
12mesenchymal cell differentiationGO:004876210.2FGFR1, FGFR2
13midbrain developmentGO:003090110.2FGFR1, FGFR2
14orbitofrontal cortex developmentGO:002176910.2FGFR1, FGFR2
15positive regulation of cardiac muscle cell proliferationGO:006004510.1FGFR1, FGFR2
16positive regulation of cell cycleGO:004578710.1FGFR1, FGFR2
17positive regulation of mesenchymal cell proliferationGO:000205310.1FGFR1, FGFR2
18embryonic limb morphogenesisGO:003032610.1FGFR1, TWIST1
19outer ear morphogenesisGO:004247310.1FGFR1, TWIST1
20regulation of smoothened signaling pathwayGO:000858910.0FGFR2, ZIC1
21skeletal system morphogenesisGO:00487059.8FGFR1, FGFR2
22fibroblast growth factor receptor signaling pathwayGO:00085439.8FGFR1, FGFR2, FGFR3
23positive regulation of neuron differentiationGO:00456669.8FGFR1, TCF12
24MAPK cascadeGO:00001659.7FGFR1, FGFR2, FGFR3
25peptidyl-tyrosine phosphorylationGO:00181089.7FGFR1, FGFR2, FGFR3
26phosphatidylinositol phosphorylationGO:00468549.7FGFR1, FGFR2, FGFR3
27phosphatidylinositol-3-phosphate biosynthetic processGO:00360929.7FGFR1, FGFR2, FGFR3
28phosphatidylinositol-mediated signalingGO:00480159.7FGFR1, FGFR2, FGFR3
29positive regulation of cell proliferationGO:00082849.7FGFR1, FGFR2, FGFR3
30positive regulation of MAPK cascadeGO:00434109.7FGFR1, FGFR2, FGFR3
31positive regulation of phospholipase activityGO:00105189.7FGFR1, FGFR2, FGFR3
32in utero embryonic developmentGO:00017019.6FGFR1, FGFR2, TWIST1
33inner ear morphogenesisGO:00424729.6FGFR1, FGFR2, ZIC1
34protein autophosphorylationGO:00467779.6FGFR1, FGFR2, FGFR3
35regulation of phosphatidylinositol 3-kinase signalingGO:00140669.5FGFR1, FGFR2, FGFR3
36ureteric bud developmentGO:00016579.4FGFR1, FGFR2
37ventricular zone neuroblast divisionGO:00218479.4FGFR1, FGFR2
38positive regulation of transcription from RNA polymerase II promoterGO:00459448.8FGFR2, TCF12, TWIST1, ZIC1

Molecular functions related to Plagiocephaly according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1bHLH transcription factor bindingGO:00434259.9TCF12, TWIST1
2E-box bindingGO:00708889.9TCF12, TWIST1
31-phosphatidylinositol-3-kinase activityGO:00163039.7FGFR1, FGFR2, FGFR3
4fibroblast growth factor bindingGO:00171349.7FGFR1, FGFR2, FGFR3
5fibroblast growth factor-activated receptor activityGO:00050079.7FGFR1, FGFR2, FGFR3
6nucleotide bindingGO:00001669.7FGFR1, FGFR2, FGFR3
7phosphatidylinositol-4,5-bisphosphate 3-kinase activityGO:00469349.7FGFR1, FGFR2, FGFR3
8protein tyrosine kinase activityGO:00047139.6FGFR1, FGFR2, FGFR3
9Ras guanyl-nucleotide exchange factor activityGO:00050889.5FGFR1, FGFR2, FGFR3
10transmembrane receptor protein tyrosine kinase activityGO:00047149.0FGFR1, FGFR2, FGFR3
11protein homodimerization activityGO:00428038.7FGFR1, FGFR2, TCF12, TWIST1

Sources for Plagiocephaly

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet