MCID: PLM005
MIFTS: 30

Pleomorphic Lipoma

Categories: Cancer diseases

Aliases & Classifications for Pleomorphic Lipoma

MalaCards integrated aliases for Pleomorphic Lipoma:

Name: Pleomorphic Lipoma 12 14 69
Lipoma 41 69
Lipomatosis, Multiple 69
Lipoma Pleomorphic 51

Classifications:



External Ids:

Disease Ontology 12 DOID:10192
MeSH 41 D008067
NCIt 46 C3703

Summaries for Pleomorphic Lipoma

Disease Ontology : 12 A lipoma that is characterized by floret giant cells with overlapping nuclei.

MalaCards based summary : Pleomorphic Lipoma, also known as lipoma, is related to well-differentiated liposarcoma and lipomatosis, multiple. An important gene associated with Pleomorphic Lipoma is HMGA2 (High Mobility Group AT-Hook 2), and among its related pathways/superpathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Glioblastoma Multiforme. Affiliated tissues include tongue, breast and adipocyte.

Related Diseases for Pleomorphic Lipoma

Diseases related to Pleomorphic Lipoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 78)
# Related Disease Score Top Affiliating Genes
1 well-differentiated liposarcoma 32.7 CDK4 HMGA2 MDM2
2 lipomatosis, multiple 31.6 CDK4 HMGA2 MDM2
3 spindle cell lipoma 30.3 CDK4 MDM2
4 atypical lipomatous tumor 30.0 CDK4 CREB3L2 HMGA2 MDM2
5 liposarcoma 29.4 CALB2 CD34 CDK4 HMGA2 MDM2
6 nasopalpebral lipoma-coloboma syndrome 12.3
7 mesenchymoma 10.5 HMGA2 MDM2
8 prostate stromal sarcoma 10.5 CD34 PGR
9 ring chromosome 7 10.5 CDK4 MDM2
10 trigonitis 10.5 CD34 PGR
11 vulvar dystrophy 10.5 CD34 PGR
12 lung meningioma 10.5 CD34 PGR
13 undifferentiated embryonal sarcoma of the liver 10.5 CDK4 MDM2
14 infiltrating angiolipoma 10.5 CDK4 MDM2
15 bone osteosarcoma 10.4 CDK4 MDM2
16 lipoblastoma 10.4 CDK4 MDM2
17 dedifferentiated liposarcoma 10.4 CDK4 HMGA2 MDM2
18 breast angiosarcoma 10.4 CD34 PGR
19 lymphoplasmacyte-rich meningioma 10.4 CD68 PGR
20 leiomyosarcoma 10.3 CDK4 MDM2 PGR
21 myxoid liposarcoma 10.3 CDK4 HMGA2 MDM2
22 malignant fibrous histiocytoma of bone 10.3 CDK4 MDM2
23 meninges sarcoma 10.3 CD34 CREB3L2
24 retina lymphoma 10.3 CD34 CD68
25 leiomyoma 10.3 CD34 HMGA2 PGR
26 extracutaneous mastocytoma 10.3 CD34 CD68
27 sternum cancer 10.3 CD34 CD68
28 extraosseous osteosarcoma 10.3 CD34 CDK4 MDM2
29 melanotic neurilemmoma 10.3 CD34 CD68
30 organ system benign neoplasm 10.3 CD34 NF1 PGR
31 plexiform schwannoma 10.3 CD34 NF1
32 cellular schwannoma 10.2 CD34 MDM2 NF1
33 heart sarcoma 10.2 CREB3L2 MDM2 SIK1
34 cell type cancer 10.2 CD34 CDK4 PGR
35 glomeruloid hemangioma 10.2 CD34 CD68
36 hemangioma of liver 10.2 CD34 CD68
37 sarcomatoid squamous cell skin carcinoma 10.2 CD34 CD68
38 spleen cancer 10.2 CD34 CD68
39 deep angioma 10.2 CD34 CREB3L2 PGR
40 intramuscular hemangioma 10.2 CD34 CREB3L2 PGR
41 fibrosarcoma of bone 10.2 CDK4 CREB3L2 MDM2
42 inflammatory leiomyosarcoma 10.2 CD68 NF1
43 scrotal carcinoma 10.2 CD68 HMGA2
44 inflammatory mfh 10.2 CD68 CDK4 MDM2
45 conventional leiomyosarcoma 10.2 CD68 HMGA2 NF1
46 atypical neurofibroma 10.2 CD34 NF1
47 verruciform xanthoma of skin 10.2 CD68 S100A9
48 angiomyoma 10.2 CD34 HMGA2
49 erythema elevatum diutinum 10.2 CD34 S100A9
50 periosteal chondrosarcoma 10.1 CDK4 MDM2

Graphical network of the top 20 diseases related to Pleomorphic Lipoma:



Diseases related to Pleomorphic Lipoma

Symptoms & Phenotypes for Pleomorphic Lipoma

Drugs & Therapeutics for Pleomorphic Lipoma

Search Clinical Trials , NIH Clinical Center for Pleomorphic Lipoma

Cochrane evidence based reviews: lipoma

Genetic Tests for Pleomorphic Lipoma

Anatomical Context for Pleomorphic Lipoma

MalaCards organs/tissues related to Pleomorphic Lipoma:

38
Tongue, Breast, Adipocyte

Publications for Pleomorphic Lipoma

Articles related to Pleomorphic Lipoma:

(show top 50) (show all 65)
# Title Authors Year
1
Pleomorphic lipoma. ( 29328546 )
2018
2
Atypical multivacuolated lipoblasts and atypical mitoses are not compatible with the diagnosis of spindle cell/pleomorphic lipoma. ( 29317234 )
2018
3
Atypical multivacuolated lipoblasts and atypical mitoses are not compatible with the diagnosis of spindle cell/pleomorphic lipoma-reply. ( 29320749 )
2018
4
Pleomorphic Lipoma of the Neck in an Infant: A Rare Clinical Entity. ( 28694582 )
2017
5
Fat Free Pleomorphic Lipoma of Oral Cavity: A Rare Entity. ( 28511518 )
2017
6
Intradermal spindle cell/pleomorphic lipoma: Case report and review of the literature. ( 28984623 )
2017
7
Combined classical spindle cell/pleomorphic lipoma spectrum imaging and clinical data. ( 28823067 )
2017
8
Uncommon Tumor, Uncommon Location: A Dermal-Based Spindle Cell/Pleomorphic Lipoma. ( 26913848 )
2016
9
Unilateral Pleomorphic Lipoma of the Eyebrow. ( 27172296 )
2015
10
Pleomorphic lipoma: A gentle giant of pathology. ( 26729985 )
2015
11
A rare case of neurofibroma with lipomatous differentiation and floret like giant cells-cytologically disguising as pleomorphic lipoma. ( 24943788 )
2014
12
Pleomorphic lipoma of the tongue as potential mimic of liposarcoma. ( 23723609 )
2013
13
Diplopia from pleomorphic lipoma of the orbit with lateral rectus muscle involvement. ( 23328779 )
2013
14
Retropharyngeal spindle cell/pleomorphic lipoma. ( 23690719 )
2013
15
A case of 'fat-free' pleomorphic lipoma occurring in the upper back and axilla simultaneously. ( 23786924 )
2013
16
Loss of retinoblastoma protein expression in spindle cell/pleomorphic lipomas and cytogenetically related tumors: an immunohistochemical study with diagnostic implications. ( 22790852 )
2012
17
Pleomorphic lipoma lacking mature fat component in extensive myxoid stroma: a great diagnostic challenge. ( 23148444 )
2012
18
Pedunculated cutaneous spindle cell/pleomorphic lipoma. ( 19678825 )
2010
19
Fine needle aspiration of pleomorphic lipoma of the neck: report of two cases. ( 19774616 )
2010
20
Spindle cell/pleomorphic lipoma of the oral cavity. ( 19881383 )
2009
21
Subconjunctival herniated orbital fat: A benign adipocytic lesion that may mimic pleomorphic lipoma and atypical lipomatous tumor. ( 17255763 )
2007
22
Pleomorphic lipoma of the oral cavity. Report of a case. ( 16688109 )
2006
23
Giant pleomorphic lipoma of the neck. ( 16462377 )
2006
24
Orbital pleomorphic lipoma in a 25-year-old male. ( 16704722 )
2006
25
Pleomorphic lipoma of the face: case report. ( 16390474 )
2006
26
Fine-needle aspiration of a pleomorphic lipoma of the head and neck: a case report. ( 15637670 )
2005
27
Pleomorphic lipoma: a definite histopathological entity. ( 15510605 )
2004
28
Pleomorphic lipoma of the orbit: a case series and review of literature. ( 12511353 )
2003
29
Pleomorphic lipoma of the tonsillar fossa--a case report. ( 15025314 )
2003
30
Atypical lipomatous tumor of the lip with pleomorphic lipoma-like myxoid area, clinically simulating mucocele. ( 12269996 )
2002
31
Benign laryngeal lesions - a clinicopathological study of eleven years and a case report of pleomorphic lipoma. ( 23119904 )
2002
32
Intradermal spindle cell/pleomorphic lipoma of the vulva: case report and review of the literature. ( 11841521 )
2002
33
Pleomorphic lipoma of the tongue. ( 11997788 )
2002
34
Fine-needle aspiration of pleomorphic lipoma. ( 11285630 )
2001
35
Angiomyxolipoma shares cytogenetic changes with lipoma, spindle cell/pleomorphic lipoma and myxoma. ( 11213837 )
2001
36
Pleomorphic lipoma with pseudopapillary structures: a pleomorphic counterpart of pseudoangiomatous spindle cell lipoma. ( 10792493 )
2000
37
Diagnostic pitfalls in fine needle aspiration cytology of pleomorphic lipoma. A case report. ( 10934961 )
2000
38
Intradermal spindle cell/pleomorphic lipoma: a distinct subset. ( 11190440 )
2000
39
Pleomorphic lipoma: case report and literature review. ( 10759828 )
2000
40
Aspiration biopsy of pleomorphic lipoma of the breast. A case report. ( 10740617 )
2000
41
Myofibroblastoma of the breast with hemangiopericytoma-like pattern and pleomorphic lipoma-like areas. Report of a case with diagnostic and histogenetic considerations. ( 10337665 )
1999
42
Aspiration cytology of a pleomorphic lipoma--a cautionary note. ( 10458506 )
1999
43
Pleomorphic lipoma on fine needle aspiration cytology. ( 9850671 )
1998
44
A case of pleomorphic lipoma of the hypopharynx. ( 9763894 )
1998
45
Pleomorphic lipoma of the parotid gland. ( 9578889 )
1998
46
Pleomorphic lipoma. ( 8669539 )
1996
47
Pleomorphic lipoma in the middle mediastinum. ( 7561568 )
1995
48
Spindle cell and pleomorphic lipoma: an ultrastructural study. ( 8597202 )
1995
49
Fine needle aspiration of pleomorphic lipoma: a potential pitfall of cytodiagnosis. ( 8453018 )
1993
50
Well-differentiated liposarcoma mimicking a pleomorphic lipoma--a case report. ( 8491861 )
1993

Variations for Pleomorphic Lipoma

Expression for Pleomorphic Lipoma

Search GEO for disease gene expression data for Pleomorphic Lipoma.

Pathways for Pleomorphic Lipoma

Pathways related to Pleomorphic Lipoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.2 CD34 CD68 FCER1A
2 10.84 CDK4 MDM2 NF1

GO Terms for Pleomorphic Lipoma

Biological processes related to Pleomorphic Lipoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 camera-type eye morphogenesis GO:0048593 8.96 EPHB2 NF1
2 paracrine signaling GO:0038001 8.62 CD34 PGR

Molecular functions related to Pleomorphic Lipoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cAMP response element binding GO:0035497 8.62 CREB3L2 HMGA2

Sources for Pleomorphic Lipoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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