MCID: PLM005
MIFTS: 28

Pleomorphic Lipoma

Categories: Cancer diseases

Aliases & Classifications for Pleomorphic Lipoma

MalaCards integrated aliases for Pleomorphic Lipoma:

Name: Pleomorphic Lipoma 12 14 69
Lipoma 42 69
Lipomatosis, Multiple 69
Lipoma Pleomorphic 52

Classifications:



External Ids:

Disease Ontology 12 DOID:10192
MeSH 42 D008067
NCIt 47 C3703
UMLS 69 C0205823

Summaries for Pleomorphic Lipoma

Disease Ontology : 12 A lipoma that is characterized by floret giant cells with overlapping nuclei.

MalaCards based summary : Pleomorphic Lipoma, also known as lipoma, is related to nasopalpebral lipoma-coloboma syndrome and transitional cell carcinoma. An important gene associated with Pleomorphic Lipoma is HMGA2 (High Mobility Group AT-Hook 2), and among its related pathways/superpathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Glioblastoma Multiforme. Affiliated tissues include tongue and adipocyte.

Wikipedia : 72 Pleomorphic lipomas, like spindle-cell lipomas, occur for the most part on the backs and necks of... more...

Related Diseases for Pleomorphic Lipoma

Diseases related to Pleomorphic Lipoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 85)
id Related Disease Score Top Affiliating Genes
1 nasopalpebral lipoma-coloboma syndrome 12.1
2 transitional cell carcinoma 10.8 HMGA2 MDM2
3 thyroiditis 10.8 CD34 PGR
4 rnase t2-deficient leukoencephalopathy 10.7 CDK4 MDM2
5 paranasal sinus disease 10.7 CD34 PGR
6 pleuropneumonia 10.7 CD34 PGR
7 verruciform xanthoma of skin 10.7 CD34 PGR
8 primary pulmonary lymphoma 10.7 CDK4 MDM2
9 epidural neoplasm 10.7 CDK4 MDM2
10 metachronous osteosarcoma of the bone 10.6 CDK4 MDM2
11 lipoic acid biosynthesis defects 10.6 CDK4 MDM2
12 secondary pulmonary hemosiderosis 10.6 CDK4 HMGA2 MDM2
13 sarcosinemia 10.6 CDK4 HMGA2 MDM2
14 vitamin d-dependent rickets, type i 10.5 CDK4 HMGA2 MDM2
15 adenosarcoma 10.5 CDK4 MDM2 PGR
16 thyroid angiosarcoma 10.5 CD34 PGR
17 common bile duct neoplasm 10.5 CD68 PGR
18 cowper gland carcinoma 10.5 CD34 CREB3L2
19 extrahepatic biliary papillomatosis 10.5 CD34 CD68
20 black piedra 10.5 CD34 HMGA2 PGR
21 filamentary keratitis 10.5 CD34 CD68
22 skin lipoma 10.5 CD34 CDK4 MDM2
23 inner ear cancer 10.5 CD34 CD68
24 coronary aneurysm 10.5 CD34 CDK4 MDM2
25 vestibular gland benign neoplasm 10.4 CD34 NF1 PGR
26 tropical spastic paraparesis 10.4 CD34 CD68
27 c-p angle neurinoma 10.4 CD34 MDM2 NF1
28 brown-vialetto-van laere syndrome 10.4 CD34 CDK4 PGR
29 salivary gland adenoid cystic carcinoma 10.4 CD34 CD68
30 demyelinating disease 10.4 CD34 NF1
31 hemopneumothorax 10.4 CD34 CD68
32 endophthalmitis 10.4 CD34 CREB3L2 PGR
33 fallopian tube squamous cell carcinoma 10.4 CD34 CD68
34 cutaneous mucoepidermoid carcinoma 10.4 CD34 CREB3L2 PGR
35 extraosseous osteosarcoma 10.4 CDK4 CREB3L2 MDM2
36 fibrillary astrocytoma 10.4 CD34 CD68
37 reactive arthritis 10.3 CD68 CDK4 MDM2
38 penis paget's disease 10.3 CD68 HMGA2
39 granular cell leiomyosarcoma 10.3 CD68 NF1
40 localized osteosarcoma 10.3 CDK4 MDM2
41 breast epithelioid hemangioma 10.3 CDK4 MDM2
42 colon leiomyosarcoma 10.3 CD68 HMGA2 NF1
43 benign pleural mesothelioma 10.3 CD34 NF1
44 giant hemangioma 10.3 CD68 S100A9
45 cardiac tuberculosis 10.3 CD34 S100A9
46 bladder urachal squamous cell carcinoma 10.3 CD34 CDK4 NF1
47 juxtacortical chondrosarcoma 10.2 CDK4 MDM2
48 endodermal sinus tumor 10.2 CD68 CREB3L2 MDM2
49 sick building syndrome 10.2 CD34 CREB3L2
50 mediastinum rhabdomyosarcoma 10.1 CD34 CREB3L2 MDM2 PGR

Graphical network of the top 20 diseases related to Pleomorphic Lipoma:



Diseases related to Pleomorphic Lipoma

Symptoms & Phenotypes for Pleomorphic Lipoma

Drugs & Therapeutics for Pleomorphic Lipoma

Search Clinical Trials , NIH Clinical Center for Pleomorphic Lipoma

Cochrane evidence based reviews: lipoma

Genetic Tests for Pleomorphic Lipoma

Anatomical Context for Pleomorphic Lipoma

MalaCards organs/tissues related to Pleomorphic Lipoma:

39
Tongue, Adipocyte

Publications for Pleomorphic Lipoma

Articles related to Pleomorphic Lipoma:

(show top 50) (show all 61)
id Title Authors Year
1
Pleomorphic Lipoma of the Neck in an Infant: A Rare Clinical Entity. ( 28694582 )
2017
2
Fat Free Pleomorphic Lipoma of Oral Cavity: A Rare Entity. ( 28511518 )
2017
3
Combined classical spindle cell/pleomorphic lipoma spectrum imaging and clinical data. ( 28823067 )
2017
4
Uncommon Tumor, Uncommon Location: A Dermal-Based Spindle Cell/Pleomorphic Lipoma. ( 26913848 )
2016
5
Pleomorphic lipoma: A gentle giant of pathology. ( 26729985 )
2015
6
Unilateral Pleomorphic Lipoma of the Eyebrow. ( 27172296 )
2015
7
A rare case of neurofibroma with lipomatous differentiation and floret like giant cells-cytologically disguising as pleomorphic lipoma. ( 24943788 )
2014
8
Diplopia from pleomorphic lipoma of the orbit with lateral rectus muscle involvement. ( 23328779 )
2013
9
A case of 'fat-free' pleomorphic lipoma occurring in the upper back and axilla simultaneously. ( 23786924 )
2013
10
Pleomorphic lipoma of the tongue as potential mimic of liposarcoma. ( 23723609 )
2013
11
Retropharyngeal spindle cell/pleomorphic lipoma. ( 23690719 )
2013
12
Loss of retinoblastoma protein expression in spindle cell/pleomorphic lipomas and cytogenetically related tumors: an immunohistochemical study with diagnostic implications. ( 22790852 )
2012
13
Pleomorphic lipoma lacking mature fat component in extensive myxoid stroma: a great diagnostic challenge. ( 23148444 )
2012
14
Fine needle aspiration of pleomorphic lipoma of the neck: report of two cases. ( 19774616 )
2010
15
Pedunculated cutaneous spindle cell/pleomorphic lipoma. ( 19678825 )
2010
16
Spindle cell/pleomorphic lipoma of the oral cavity. ( 19881383 )
2009
17
Subconjunctival herniated orbital fat: A benign adipocytic lesion that may mimic pleomorphic lipoma and atypical lipomatous tumor. ( 17255763 )
2007
18
Orbital pleomorphic lipoma in a 25-year-old male. ( 16704722 )
2006
19
Giant pleomorphic lipoma of the neck. ( 16462377 )
2006
20
Pleomorphic lipoma of the face: case report. ( 16390474 )
2006
21
Pleomorphic lipoma of the oral cavity. Report of a case. ( 16688109 )
2006
22
Fine-needle aspiration of a pleomorphic lipoma of the head and neck: a case report. ( 15637670 )
2005
23
Pleomorphic lipoma: a definite histopathological entity. ( 15510605 )
2004
24
Pleomorphic lipoma of the orbit: a case series and review of literature. ( 12511353 )
2003
25
Pleomorphic lipoma of the tonsillar fossa--a case report. ( 15025314 )
2003
26
Pleomorphic lipoma of the tongue. ( 11997788 )
2002
27
Intradermal spindle cell/pleomorphic lipoma of the vulva: case report and review of the literature. ( 11841521 )
2002
28
Benign laryngeal lesions - a clinicopathological study of eleven years and a case report of pleomorphic lipoma. ( 23119904 )
2002
29
Atypical lipomatous tumor of the lip with pleomorphic lipoma-like myxoid area, clinically simulating mucocele. ( 12269996 )
2002
30
Angiomyxolipoma shares cytogenetic changes with lipoma, spindle cell/pleomorphic lipoma and myxoma. ( 11213837 )
2001
31
Fine-needle aspiration of pleomorphic lipoma. ( 11285630 )
2001
32
Intradermal spindle cell/pleomorphic lipoma: a distinct subset. ( 11190440 )
2000
33
Diagnostic pitfalls in fine needle aspiration cytology of pleomorphic lipoma. A case report. ( 10934961 )
2000
34
Aspiration biopsy of pleomorphic lipoma of the breast. A case report. ( 10740617 )
2000
35
Pleomorphic lipoma with pseudopapillary structures: a pleomorphic counterpart of pseudoangiomatous spindle cell lipoma. ( 10792493 )
2000
36
Pleomorphic lipoma: case report and literature review. ( 10759828 )
2000
37
Myofibroblastoma of the breast with hemangiopericytoma-like pattern and pleomorphic lipoma-like areas. Report of a case with diagnostic and histogenetic considerations. ( 10337665 )
1999
38
Aspiration cytology of a pleomorphic lipoma--a cautionary note. ( 10458506 )
1999
39
Pleomorphic lipoma on fine needle aspiration cytology. ( 9850671 )
1998
40
A case of pleomorphic lipoma of the hypopharynx. ( 9763894 )
1998
41
Pleomorphic lipoma of the parotid gland. ( 9578889 )
1998
42
Pleomorphic lipoma. ( 8669539 )
1996
43
Pleomorphic lipoma in the middle mediastinum. ( 7561568 )
1995
44
Spindle cell and pleomorphic lipoma: an ultrastructural study. ( 8597202 )
1995
45
Well-differentiated liposarcoma mimicking a pleomorphic lipoma--a case report. ( 8491861 )
1993
46
Fine needle aspiration of pleomorphic lipoma: a potential pitfall of cytodiagnosis. ( 8453018 )
1993
47
Pleomorphic lipoma. Case reports and review of the literature. ( 1541750 )
1992
48
Pleomorphic lipoma. Case report and discussion of "atypical" lipomatous tumors. ( 1430473 )
1992
49
Pleomorphic lipoma--a case report. ( 1794909 )
1991
50
Spindle cell and pleomorphic lipoma: an immunohistochemical study and histogenetic analysis. ( 2769483 )
1989

Variations for Pleomorphic Lipoma

Expression for Pleomorphic Lipoma

Search GEO for disease gene expression data for Pleomorphic Lipoma.

Pathways for Pleomorphic Lipoma

Pathways related to Pleomorphic Lipoma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.2 CD34 CD68 FCER1A
2 10.84 CDK4 MDM2 NF1

GO Terms for Pleomorphic Lipoma

Biological processes related to Pleomorphic Lipoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 negative regulation of cell cycle arrest GO:0071157 8.96 CDK4 MDM2
2 paracrine signaling GO:0038001 8.62 CD34 PGR

Molecular functions related to Pleomorphic Lipoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cAMP response element binding GO:0035497 8.62 CREB3L2 HMGA2

Sources for Pleomorphic Lipoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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