PXA
MCID: PLM020
MIFTS: 42

Pleomorphic Xanthoastrocytoma (PXA) malady

Categories: Rare diseases, Neuronal diseases, Cancer diseases

Aliases & Classifications for Pleomorphic Xanthoastrocytoma

About this section
Sources:
11Disease Ontology, 13DISEASES, 31ICD10 via Orphanet, 45NCIt, 48NIH Rare Diseases, 54Orphanet, 62SNOMED-CT, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Pleomorphic Xanthoastrocytoma:

Name: Pleomorphic Xanthoastrocytoma 11 48 54 13 68
Pxa 48 54
 
Pleomorphic Xantho-Astrocytoma 11

Characteristics:

Orphanet epidemiological data:

54
pleomorphic xanthoastrocytoma:
Inheritance: Not applicable; Age of onset: All ages

Classifications:



External Ids:

Disease Ontology11 DOID:4852
NCIt45 C4323
Orphanet54 ORPHA251607
SNOMED-CT62 189924002, 78838008
ICD10 via Orphanet31 C71.9
UMLS via Orphanet69 C0334586

Summaries for Pleomorphic Xanthoastrocytoma

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Wikipedia:71 Pleomorphic xanthoastrocytoma (PXA) is a brain tumor that occurs most frequently in children and... more...

MalaCards based summary: Pleomorphic Xanthoastrocytoma, also known as PXA, is related to pilocytic astrocytoma and glioblastoma, and has symptoms including seizures An important gene associated with Pleomorphic Xanthoastrocytoma is GFAP (Glial Fibrillary Acidic Protein), and among its related pathways are Thyroid cancer and LKB1 signaling events. Affiliated tissues include brain, temporal lobe and spinal cord, and related mouse phenotypes are Increased proliferation and Decreased viability in esophageal squamous lineage.

Related Diseases for Pleomorphic Xanthoastrocytoma

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Diseases related to Pleomorphic Xanthoastrocytoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 193)
idRelated DiseaseScoreTop Affiliating Genes
1pilocytic astrocytoma30.1GFAP, SYP
2glioblastoma10.4
3ganglioglioma10.3
4neurofibromatosis10.3
5diabetes hypogonadism deafness mental retardation10.3GFAP, SYP
6papillary tumor of the pineal region10.3GFAP, SYP
7biliary papillomatosis10.3BRAF, GFAP
8intrahepatic bile duct adenoma10.3GFAP, SYP
9pilocytic astrocytoma of cerebellum10.3GFAP, SYP
10epidermal appendage tumor10.3GFAP, SYP
11nephrogenic adenoma of urinary bladder10.3GFAP, SYP
12cerebral folate receptor alpha deficiency10.3GFAP, SYP
13behcet's syndrome arthropathy10.3GFAP, SYP
14well-differentiated thymic neuroendocrine carcinoma10.3BRAF, TP53
15pineal gland astrocytoma10.3BRAF, TP53
16aneurysm of sinus of valsalva10.3GFAP, SYP
17spondylarthropathy10.3BRAF, TP53
18male reproductive system disease10.3GFAP, SYP
19mediastinal granular cell myoblastoma10.3GFAP, SYP
20thrombophlebitis10.3GFAP, SMARCB1
21tmem70 defect10.3BRAF, TP53
22central neurocytoma10.2GFAP, SYP
23infantile thalamic degeneration10.2BRAF, TP53
24scarlet fever10.2BRAF, TP53
25liver fibrosarcoma10.2GFAP, TP53
26hypogonadotropic hypogonadism-retinitis pigmentosa syndrome10.2GFAP, SYP
27cervical adenoid cystic carcinoma10.2GFAP, TP53
28ovarian large-cell neuroendocrine carcinoma10.2SMARCB1, SYP
29familial hypopituitarism10.2BRAF, TP53
30intestinal pseudo-obstruction10.2GFAP, SMARCB1
31neurofibromatosis, type 110.2
32bronchitis10.2GFAP, TP53
33bile duct clear cell adenocarcinoma10.2GFAP, TP53
34pneumothorax10.2GFAP, SYP
35porokeratosis10.2GFAP, TP53
36kidney disease10.2SYP, TP53
37inhibited male orgasm10.2BRAF, TP53
38auricular cancer10.2GFAP, SYP
39adult brainstem gliosarcoma10.2GFAP, TP53
40middle ear disease10.2GFAP, TP53
41ophn1 syndrome10.2GFAP, MGMT
42bone deterioration disease10.2SYP, TP53
43paraphimosis10.2SYP, TP53
44mixed epithelial stromal tumour10.2GFAP, TP53
45astrocytoma10.2
46gallbladder pleomorphic giant cell adenocarcinoma10.2SYP, TP53
47adult epithelioid sarcoma10.2SYP, TP53
48childhood embryonal testis carcinoma10.2GFAP, TP53
49peroneal nerve paralysis10.2CHGA, SYP
50glomangioma10.2SYP, TP53

Graphical network of the top 20 diseases related to Pleomorphic Xanthoastrocytoma:



Diseases related to pleomorphic xanthoastrocytoma

Symptoms & Phenotypes for Pleomorphic Xanthoastrocytoma

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UMLS symptoms related to Pleomorphic Xanthoastrocytoma:


seizures

GenomeRNAi Phenotypes related to Pleomorphic Xanthoastrocytoma according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00094-A10.4SMARCB1, TP53
2GR00235-A7.7BRAF, CHGA, GFAP, MAP2, SMARCB1, SYNM

MGI Mouse Phenotypes related to Pleomorphic Xanthoastrocytoma according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053698.4BRAF, GFAP, SMARCB1, SYNM, TP53
2MP:00053868.0BRAF, GFAP, MAP2, SMARCB1, SYNM, SYP

Drugs & Therapeutics for Pleomorphic Xanthoastrocytoma

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Drugs for Pleomorphic Xanthoastrocytoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 55)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Histamineapproved, investigationalPhase 3105075614-87-8, 51-45-6774
Synonyms:
.beta.-Imidazolyl-4-ethylamine
1H-Imidazole-4-ethanamine
1H-Imidazole-5-ethanamine
1avn
1qft
2-(1H-Imidazol-4-yl)ethanamine
2-(1H-Imidazol-4-yl)ethylamine
2-(1H-Imidazol-5-yl)ethanamine
2-(1H-Imidazol-5-yl)ethylamine
2-(1H-imidazol-4-yl)ethan-1-amine
2-(1H-imidazol-5-yl)ethanamine
2-(3H-Imidazol-4-yl)-ethylamine
2-(4-Imidazolyl)ethanamine
2-(4-Imidazolyl)ethylamine
2-(4-imidazolyl)ethylamine
2-Imidazol-4-yl-Ethylamine
2-Imidazol-4-ylethylamine
2-[4-Imidazolyl]ethylamine
4-(2-Aminoethyl)-1H-imidazole
4-(2-Aminoethyl)imidazole
4-Imidazoleethylamine
4-imidazoleethylamine
5-Imidazoleethylamine
5-imidazoleethylamine
51-45-6
53290_FLUKA
64422-25-9
924364-91-0
AC-13185
AC1L19ZT
AC1Q54BV
AC1Q54BW
AKOS000274386
ALBB-005968
BCBcMAP01_000250
BSPBio_001117
BSPBio_002124
Bio1_000487
Bio1_000976
Bio1_001465
Bio2_000389
Bio2_000869
C00388
CCRIS 6535
CHEBI:18295
CHEMBL90
CID774
D08040
DivK1c_000308
EINECS 200-100-6
Eramin
Ergamine
Ergotidine
F411C768-A159-4FC0-A195-291A08BB03AA
Free histamine
H7125_SIGMA
HMS1362G19
HMS1792G19
HMS1990G19
HSDB 3338
HSM
Histamine
Histamine (DCF)
Histamine Base
Histamine [USAN]
Histamine, Free Base
Histaminum
 
Histaminum (TN)
IDI1_000308
IDI1_002144
Imidazole-4-ethylamine
Istamina
Istamina [Italian]
KBio1_000308
KBio2_000457
KBio2_001325
KBio2_003025
KBio2_003893
KBio2_005593
KBio2_006461
KBio3_000853
KBio3_000854
KBio3_001344
KBioGR_000457
KBioGR_001580
KBioSS_000457
KBioSS_001325
L-Histamin base
L-Histamine
L-histamine
L000292
LS-75835
Lopac-H-7250
Lopac0_000595
MLS000069447
MolPort-001-785-597
MolPort-002-042-264
NCGC00015513-01
NCGC00015513-08
NCGC00093371-02
NCGC00093371-03
NCGC00093371-04
NCGC00093371-05
NINDS_000308
NSC 33792
NSC33792
SDCCGMLS-0066601.P001
SMP1_000151
SMR000059091
SPBio_000729
ST073926
STK346752
STOCK5S-55669
Spectrum2_000665
Spectrum3_000452
Spectrum4_000960
Spectrum5_000796
Spectrum_000845
Theramine
UNII-820484N8I3
WLN: T5M CNJ D2Z
ZERO/004089
[3H]histamine
b-Imidazolyl-4-ethylamine
beta-Aminoethylglyoxaline
beta-Aminoethylimidazole
beta-Aminothethylglyoxaline
beta-Imidazolyl-4-ethylamine
beta-aminoethylglyoxaline
beta-aminoethylimidazole
beta-aminothethylglyoxaline
bmse000744
histamine
nchembio.87-comp54
nchembio714-comp1
2
CyproheptadineapprovedPhase 320129-03-32913
Synonyms:
1-Methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine
1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)piperidine
1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine
129-03-3
4-(5-Dibenzo(a,D)cyclohepten-5-ylidine)-1-methylpiperidine
4-(5-Dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine
4-(5H-Dibenzo(a,D)cyclohepten-5-ylidene)-1-methylpiperidine
4-(5H-Dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidene
4-(5H-Dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidine
4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine
4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine
4-Dibenzo[a,D]cyclohepten-5-ylidene-1-methyl-piperidine
41354-29-4
5-(1-Methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene
5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene
5-20-08-00500 (Beilstein Handbook Reference)
AC1L1ER8
AKOS004119847
Axoprol
BIDD:GT0324
BPBio1_000096
BPBio1_000155
BRD-K28143534-001-01-4
BRD-K28143534-003-03-6
BRN 1685976
BSPBio_000086
Biomol-NT_000131
C06935
CAS-969-33-5
CCRIS 5232
CHEBI:4046
CHEMBL516
CID2913
CYPROHEPTADINE
Ciproheptadina
Ciproheptadina [INN-Spanish]
Ciprovit
Ciprovit (TN)
Cypoheptadine
Cyproheptadiene
Cyproheptadin
Cyproheptadine
 
Cyproheptadine (INN)
Cyproheptadine Hcl
Cyproheptadine [INN:BAN]
Cyproheptadinum
Cyproheptadinum [INN-Latin]
D07765
DB00434
Dibenzosuberonone/Cyproheptadine
Dihexazin
Dronactin
EINECS 204-928-9
Eiproheptadine
Glutodina
HMS2090P20
HSDB 3048
L001016
LS-114933
Lopac-C-6022
Lopac0_000246
MK 141
MolPort-002-507-777
NCGC00015252-01
NCGC00015252-02
NCGC00015252-03
NCGC00015252-09
NCGC00024293-02
NCGC00024293-04
NCGC00024293-05
Oprea1_498140
PDSP1_001229
PDSP2_001213
Periactin
Periactine
Periactinol
Prestwick0_000103
Prestwick1_000103
Prestwick2_000103
Prestwick3_000103
SPBio_002025
STK802098
Tocris-0996
UNII-2YHB6175DO
Viternum
nchembio.559-comp10
3Dermatologic AgentsPhase 3, Phase 15806
4
SerotoninPhase 3362750-67-95202
Synonyms:
3-(2-Aminoethyl)-1H-indol-5-ol
3-(2-Aminoethyl)indol-5-ol
3-(b-Aminoethyl)-5-hydroxyindole
5-HT
5-HTA
5-Hydroxy-3-(b-aminoethyl)indole
 
5-Hydroxy-tryptamine
5-Hydroxyltryptamine
5-Hydroxytriptamine
5-Hydroxytryptamine
Antemovis
DS substance
Enteramin
Enteramine
5Serotonin AgentsPhase 33156
6Anti-Allergic AgentsPhase 31522
7Serotonin AntagonistsPhase 31409
8
Histamine PhosphatePhase 3104951-74-165513
Synonyms:
1H-Imidazole-4-ethanamine, phosphate (1:2)
2-Imidazol-4-ylethylamine orthophosphoric acid (1:2)
4-(2-Aminoethyl)imidazole bis(dihydrogen phosphate)
4-(2-Aminoethyl)imidazole di-acid phosphate
4-2(2-Aminoethyl)Imidazole-Di-Acid Phosphate
51-74-1
53623-99-7
74-56-6
AC1L23E4
CID65513
D04445
DB00667
 
EINECS 200-118-4
H0147
Histamine acid phosphate
Histamine biphosphate
Histamine dihydrogen phosphate
Histamine diphosphate
Histamine phosphate (1:2)
Histamine phosphate (TN)
Histamine phosphate (USP)
Histamine phosphate [USP]
Histamine positive
LS-78569
UNII-QWB37T4WZZ
9Neurotransmitter AgentsPhase 318340
10AntipruriticsPhase 3841
11Histamine AntagonistsPhase 3961
12Gastrointestinal AgentsPhase 38402
13Histamine H1 AntagonistsPhase 3791
14
Irinotecanapproved, investigationalPhase 1, Phase 2112397682-44-5, 100286-90-660838
Synonyms:
(+)-Irinotecan
(4S)-4,11-DIETHYL-4-HYDROXY-3,14-DIOXO-3,4,12,14-TETRAHYDRO-1H-PYRANO[3',4':6,7]INDOLIZINO[1,2-B]QUINOLIN-9-YL 1,4'-BIPIPERIDINE-1'-CARBOXYLATE
(4S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-4,12-dihydro-1H-pyrano[3,4-f]quinolino[2,3-a]indolizin-9-yl 4-piperidylpiperidinecarboxylate
1u65
97682-44-5
AC-7469
AC1L1U0Z
AC1Q6PGI
BRD-K08547377-003-02-4
BSPBio_002346
Bio-0054
Biotecan
Biotecan (TN)
C16641
C33H38N4O6
CHEBI:105985
CHEMBL481
CID60838
CP0
Campothecin-11
Campto
Camptosar
 
Camptosar, Campto, CPT-11, Irinotecan
Camptothecin-11
D08086
DB00762
FT-0083650
HSDB 7607
IRINOTECAN HYDROCHLORIDE Trihydrate
IRINOTECAN, CPT-11
Irinotecan (INN)
Irinotecan Hcl
Irinotecan Hydrochloride
Irinotecan Hydrochloride Trihydrate
Irinotecan [INN:BAN]
Irinotecan hydrochloride
Irinotecanum
Irinotecanum [INN-Latin]
LS-44589
NCI60_005051
NSC728073
S1198_Selleck
TL8006026
UNII-7673326042
irinotecan
15
CarboplatinapprovedPhase 1, Phase 2205041575-94-410339178, 498142, 38904
Synonyms:
(SP-4-2)-diammine[cyclobutane-1,1-dicarboxylato(2-)-kappa(2)O,O']platinum
/h1-3H2,(H,7,8)(H,9,10)
/q
1,1-Cyclobutanedicarboxylate diammine platinum (II)
1,1-Cyclobutanedicarboxylate diammine platinum(II)
2*-1
2*1H2
41575-94-4
70903-55-8
AC-1457
AC1L8I6U
Ambap41575-94-4
BSPBio_003145
C 2538
C2043
C2538_SIGMA
C6H10N2O4Pt
CBDCA
CCRIS 3404
CHEBI:31355
CHEMBL1351
CHEMBL288376
CID10339178
CID2567
CID38904
CID426756
CID498142
CID5352133
CID6398587
CID6603770
Carbopaltin
Carboplatin
Carboplatin (JAN/USP/INN)
Carboplatin (USAN)
Carboplatin [USAN:INN:BAN:JAN]
Carboplatine
Carboplatine [French]
Carboplatino
Carboplatino [Spanish]
Carboplatinum
Carboplatinum [Latin]
Cbdca
Cyclobutane-1,1-dicarboxylate
D01363
DB00958
Diammine(1,1-cyclobutanedicarboxylato)platinum (II)
Diammine(cyclobutane-1,1-dicarboxylato(2-)-O,O')platinum
Diammine-1,1-cyclobutane dicarboxylate platinum II
DivK1c_000892
EINECS 255-446-0
EU-0100230
Ercar
HMS1921J16
HMS2090M05
HMS2092B22
HMS502M14
HSDB 6957
I14-2390
IDI1_000892
IUPAC: Azane
InChI=1/C6H8O4.2H2N.Pt/c7-4(8)6(5(9)10)2-1-3-6
 
JM 8
JM-8
KBio1_000892
KBio2_002009
KBio2_004577
KBio2_007145
KBio3_002645
KBioGR_000713
KBioSS_002009
LS-117689
Lopac-C-2538
Lopac0_000230
MolPort-003-665-501
MolPort-003-845-609
NCGC00015223-01
NCGC00093695-01
NCGC00094961-01
NCGC00094961-02
NCGC00094961-03
NCGC00162099-01
NCGC00162099-02
NCGC00167800-01
NCGC00178242-01
NINDS_000892
NSC 201345
NSC 241240
NSC-241240
NSC201345
NSC241240
Paraplatin
Paraplatin (TN)
Paraplatin, Carboplatin
Paraplatin-AQ
Platinum(+2) Cation
Platinum(II), (1, 1-cyclobutanedicar
Platinum, diammine(1,1-cyclobutanedicarboxylato(2-)-O,O')-, (SP-4-2)
Platinum, {diammine[1,1-cyclobut
S1215_Selleck
SPBio_000716
SPECTRUM1502106
Spectrum2_000898
Spectrum3_001503
Spectrum4_000337
Spectrum5_001094
Spectrum_001529
UNII-BG3F62OND5
azanide
carboplatin
cis -Diammine[1,1-cyclobutane-dicarboxylato] platinum
cis-(1,1-Cyclobutanedicarboxylato)diammineplatinum(II)
cis-(1,1-Cyclobutanedicarboxylato)diammineplatinum(ii)
cis-Diamine(1,1-cyclobutanedicarboxylato)platinum(II)
cis-Diamine[1,1-cyclobutanedicarboxylato]platinum(II)
cis-Diammine(1,1-cyclobutanedicarboxylato) platinum
cis-Diammine(1,1-cyclobutanedicarboxylato)platinum
cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II)
cis-Diammine(cyclobutanedicarboxylato)platinum II
cyclobutane-1,1-dicarboxylic acid
diammine[cyclobutane-1,1-dicarboxylato(2-)-k2O1,O1]platinum
nchembio.573-comp10
nchembio773-comp2
nchembio873-comp3
platinum(2+)
16
Mebendazoleapproved, vet_approvedPhase 1, Phase 22431431-39-74030
Synonyms:
(5-Benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl ester
(5-Benzoyl-1H-benzimidazol-2-yl)carbamic acid methyl ester
(5-Benzoyl-1H-benzoimidazol-2-yl)-carbamic acid methyl ester
(5-benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl ester
2-Benzimidazolecarbamic acid, 5-benzoyl-, methyl ester
2-Benzimidazolecarbamic acid, 5-benzoyl-, methyl ester (8CI)
31431-39-7
46404_FLUKA
46404_RIEDEL
5-Benzoyl-2-benzimidazolecarbamic acid methyl ester
5-Benzoyl-2-benzimidazolecarbamic acid, methyl ester
AB00052203
AC-12064
AC1L1H98
AC1Q44DR
AKOS000539066
Abello Farmacia Brand of Mebendazole
Anti Worm
Anti-Worm
Ardeypharm Brand of Mebendazole
BAS 00341140
BIDD:GT0087
BPBio1_000257
BRD-K77987382-001-01-7
BRD-K77987382-001-06-6
BSPBio_000233
BSPBio_003178
Bantenol
Banworm
Besantin
Bio-0458
Bio-0803
Boots Brand of Mebendazole
Boots Threadworm Treatment
CAS-31431-39-7
CBDivE_010559
CCRIS 4479
CHEBI:6704
CHEMBL685
CID4030
CPD000036734
Carbamic acid, (5-benzoyl-1H-benzimidazol-2-yl)-, methyl ester
Carbamic acid, (5-benzoyl-1H-benzimidazol-2-yl)-, methyl ester (9CI)
Carbamic acid, N-(5-benzoylbenzimidazol-2-yl)-, methyl ester
D00368
D008463
DB00643
Degort's Brand of Mebendazole
Diba Brand of Mebendazole
DivK1c_000751
EINECS 250-635-4
Elfar Brand of Mebendazole
Equivurm Plus
Esteve Brand of Mebendazole
HMS1536H11
HMS1568L15
HMS1921F03
HMS2090B03
HMS2092B15
HMS502F13
HSDB 3232
Healthypharm Brand of Mebendazole
I06-2075
IDI1_000751
Janssen Brand of Mebendazole
KBio1_000751
KBio2_001778
KBio2_004346
KBio2_006914
KBio3_002398
KBioGR_000712
KBioSS_001778
LS-48951
Leidapharm Brand of Mebendazole
Lomper
M2523_FLUKA
M2523_SIGMA
MBDZ
MEBENDAZOLE, 99%
MLS000028491
Madicure
Mebendan
Mebendazol
Mebendazol [INN-Spanish]
Mebendazole (JAN/USP)
 
Mebendazole (JAN/USP/INN)
Mebendazole [USAN:INN:BAN:JAN]
Mebendazole(USAN)
Mebendazolum
Mebendazolum [INN-Latin]
Mebenoazole
Mebenvet
Mebex
Mebutar
Methyl 5-benzoyl benzimidazole-2-carbamate
Methyl 5-benzoyl-2-benzimidazolecarbamate
Methyl 5-benzoyl-2-benzimidazolylcarbamate
Methyl N-(5-benzoyl-1H-benzimidazol-2-yl)carbamate
Methyl N-(5-benzoyl-2-benzimidazolyl)carbamate
MolPort-000-765-625
MolPort-001-889-615
Mébendazole
N-(Benzoyl-5, benzimidazolyl)-2, carbamate de methyle
N-(Benzoyl-5, benzimidazolyl)-2, carbamate de methyle [French]
N-2 (5-Benzoyl-benzimidazole) carbamate de methyle
N-2 (5-Benzoyl-benzimidazole) carbamate de methyle [French]
NCGC00016806-01
NCGC00016806-02
NCGC00021698-03
NCGC00021698-04
NCGC00021698-05
NCGC00021698-06
NINDS_000751
NSC 184849
NSC184849
Norgine Brand of Mebendazole
Noverme
Oprea1_278237
Oprea1_768530
Ovitelmin
Pantelmin
Pfizer Brand of Mebendazole
Prestwick0_000217
Prestwick1_000217
Prestwick2_000217
Prestwick3_000217
Prestwick_310
Pripsen Mebendazole
Probes1_000013
Probes2_000149
R 17,635
R 17635
R-17635
R17635
SAM002548959
SMR000036734
SPBio_001442
SPBio_002154
SPECTRUM1501110
SSL Brand of Mebendazole
STK093862
Spectrum2_001401
Spectrum3_001439
Spectrum4_000416
Spectrum5_001381
Spectrum_001298
Sqworm
Streger Brand of Mebendazole
Sufil
Surfont
TL8002405
Taxandria Brand of Mebendazole
Tedec Meiji Brand of Mebendazole
Telmin
TimTec1_000869
UNII-81G6I5V05I
Vermicidin
Vermicol
Vermidil
Vermin
Vermirax
Vermox
Vermox (TN)
Verpanyl
Versid
Wormkuur
ZINC00121541
mebendazole
methyl (5-benzoyl-1H-benzimidazol-2-yl)carbamate
methyl N-(6-benzoyl-1H-1,3-benzodiazol-2-yl)carbamate
methyl N-(6-benzoyl-1H-benzimidazol-2-yl)carbamate
methyl [5-(phenylcarbonyl)-1H-benzimidazol-2-yl]carbamate
17
Temozolomideapproved, investigationalPhase 1, Phase 271185622-93-15394
Synonyms:
3,4-Dihydro-3-methyl-4-oxoimidazo(5,1-d)-1,2,3,5-tetrazine-8-carboxamide
3,4-Dihydro-3-methyl-4-oxoimidazo(5,1-d)-as-tetrazine-8-carboxamide
3,4-dihydro-3-Methyl-4-oxoimidazo(5,1-D)-1,2,3,5-tetrazine-8-carboxamide
3,4-dihydro-3-Methyl-4-oxoimidazo(5,1-D)-as-tetrazine-8-carboxamide
3-Methyl-4-oxo-3,4-dihydroimidazo(5,1-D)(1,2,3,5)tetrazine-8-carboxamide
3-Methyl-4-oxo-3,4-dihydroimidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide
3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetraazine-8-carboxamide
3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
8-Carbamoyl-3-methylimidazo(5,1-D)-1,2,3,5-tetrazin-4(3H)-one
8-Carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3H)-one
85622-93-1
AC-758
AC1L1K9B
BIDD:GT0204
BRN 5547136
Bio-0147
C047246
C6H6N6O2
CCRG 81045
CCRG-81045
CCRIS 8996
CHEBI:153686
CHEMBL810
CID5394
CPD000466338
D06067
DB00853
Essex brand of temozolomide
HMS2051O12
HMS2090B08
I06-0149
I14-1943
LS-80558
M B 39831
M & B 39831
M&B 39831
M&B-39831
 
M-39831
MB 39831
MLS000759447
MLS001424028
MLS002701861
Methazolastone
NCGC00167429-01
NCGC00167429-02
NCI60_003316
NSC 362856
NSC-362856
NSC362856
SAM001246636
SMR000466338
STK623541
Sch 52365
Sch-52365
Schering brand of temozolomide
Schering-Plough brand of temozolomide
TL8005593
TMZ
TMZ-Bioshuttle
Temodal
Temodal (TN)
Temodar
Temozolamide
Temozolodida
Temozolodida [Spanish]
Temozolomid
Temozolomida
Temozolomide (JAN/USAN/INN)
Temozolomide [INN:BAN]
Temozolomidum
Temozolomidum [Latin]
Témozolomide
UNII-YF1K15M17Y
ZINC01482184
m & b 39831
temozolomide
18
Vincristineapproved, investigationalPhase 1, Phase 29222068-78-2, 57-22-75978
Synonyms:
22-Oxovincaleukoblastin
22-Oxovincaleukoblastine
28379-27-3
57-22-7
AC1L1LJC
C07204
C46H56N4O10
CCRIS 5763
CHEBI:28445
CID5978
D08679
DB00541
EINECS 200-318-1
HMS2090E19
HSDB 3199
Indole alkaloid
LCR
LS-228
Leurocristine
Lilly 37231 (1:1 sulfate salt)
Liposomal Vincristine
Marqibo
NCGC00163700-01
NCI-C04864
NCI60_026703
NSC-67574
Onco TCS
 
Oncovin
Oncovin (1:1 sulfate salt)
Oncovine
Tecnocris
Tecnocris (TN)
UNII-5J49Q6B70F
VCR
VIN
Vincaleukoblastine, 22-oxo- 22-Oxovincaleukoblastine
Vincasar
Vincasar (1:1 sulfate salt)
Vincasar PFS
Vincrex
Vincrex (1:1 sulfate salt)
Vincristin
Vincristina
Vincristina [DCIT]
Vincristine (INN)
Vincristine Sulfate
Vincristine Sulfate PFS
Vincristine [INN:BAN]
Vincristinum
Vincristinum [INN-Latin]
Vincrstine
Vincrystine
Vinkristin
Z-D-Val-Lys(Z)-OH
vincristine
19
Bevacizumabapproved, investigationalPhase 1, Phase 22020216974-75-3
Synonyms:
216974-75-3
Avastin
Avastin (TN)
Bevacizumab
Bevacizumab (genetical recombination)
 
Bevacizumab (genetical recombination) (JAN)
D06409
R-435
anti-VEGF monoclonal antibody
antiVEGF
bevacizumab
20
Piperazineapproved, vet_approvedPhase 1, Phase 224110-85-04837
Synonyms:
1,4-Diazacyclohexane
1,4-Diethylenediamine
1,4-Piperazine
110-85-0
14007-05-7 (unspecified hydrobromide)
142-63-2 (hexahydrate)
142-64-3 (di-hydrochloride)
14538-56-8 (phosphate[1:1])
16832-43-2 (unspecified hydrate)
1951-97-9 (unspecified phosphate)
3597-26-0 (unspecified sulfate)
5-23-01-00030 (Beilstein Handbook Reference)
6094-40-2 (unspecified hydrochloride)
7542-23-6 (mono-hydrochloride)
8017-90-1
8027-81-4
8057-14-5 (unspecified salt)
80621_FLUKA
854880-15-2
861800-35-3
AB1003720
AC1L1J2E
AC1Q1IA7
AC1Q1IA8
AC1Q1IA9
AKOS000269028
AR-1L1009
ARONIS23910
Anthalazine
Antiren
Asca-Trol No. 3
BIDD:GT0273
BRN 0102555
C07973
CCRIS 5950
CHEBI:28568
CHEMBL1412
CID4837
D00807
DB00592
Diethylenediamine
Diethyleneimine
Dispermine
DivK1c_000038
EINECS 203-808-3
Eraverm
Eraverm (VAN)
Fluphenazine dihydrochloride
HMS1920H20
HMS2092A03
HMS500B20
HSDB 1093
Hexahydro-1,4-diazine
Hexahydropyrazine
I14-11172
IDI1_000038
InChI=1/C4H10N2/c1-2-6-4-3-5-1/h5-6H,1-4H
Jsp000824
KBio1_000038
KBio2_001593
KBio2_004161
KBio2_006729
KBioSS_001593
LS-517
LTBB000432
Lumbrical
MolPort-000-872-010
NCGC00094762-01
NCGC00094762-02
NCIOpen2_000984
NCIOpen2_000988
NCIOpen2_001024
NCIOpen2_001031
NCIOpen2_001033
NCIOpen2_001071
 
NCIOpen2_001073
NCIOpen2_001111
NCIOpen2_001151
NCIOpen2_001231
NCIOpen2_001262
NCIOpen2_001269
NCIOpen2_004830
NCIOpen2_004834
NCIOpen2_004862
NCIOpen2_004874
NCIOpen2_004904
NCIOpen2_004910
NCIOpen2_004914
NCIOpen2_004942
NCIOpen2_004952
NCIOpen2_004954
NCIOpen2_004982
NCIOpen2_004992
NCIOpen2_004994
NCIOpen2_005022
NCIOpen2_005032
NCIOpen2_005034
NCIOpen2_005062
NCIOpen2_005072
NCIOpen2_005102
NCIOpen2_005108
NCIOpen2_005145
NCIOpen2_005182
NCIOpen2_005185
NCIOpen2_005187
NCIOpen2_005200
NCIOpen2_005575
NCIOpen2_005980
NCIOpen2_009422
NINDS_000038
NSC 474
NSC474
P0446
P0447
P45907_SIAL
PIPERAZINE (HEXAHYDRATE)
PZE
Piperazidine
Piperazin
Piperazin [German]
Piperazin [Germany]
Piperazine (USP)
Piperazine Dihydrochloride Dihydrochloride Hydrate
Piperazine Hexa-Hydrate
Piperazine [UN2579] [Corrosive]
Piperazine [UN2579] [Corrosive]
Piperazine [USAN]
Piperazine anhydrous
Piperazine hexahydrate
Piperazine hydrate
Piperazine, anhydrous
Pipersol
Pyrazine hexahydride
Pyrazine, hexahy
SPECTRUM1500490
Spectrum5_001817
Spectrum_001113
UN2579
UNII-1RTM4PAL0V
Upixon
Uvilon
Vermex
Vermizine
Vermizine (TN)
WLN: T6M DMTJ
Worm-A-Ton
Worm-away
Wurmirazin
nchembio814-comp12
piperazine
piperazinium oleate
21
Dacarbazineapproved, investigationalPhase 1, Phase 26884342-03-45351166
Synonyms:
(5E)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide
(5Z)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide
(Dimethyltriazeno)imidazolecarboxamide
37626-23-6
4(5)-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide
4(5)-(3,3-Dimethyl-1-triazeno)imidazole-5(4)-carboxamide
4-(3,3-Dimethyl-1-triazeno)imidazole-5-carboxamide
4-(3,3-Dimethyltriazeno)imidazole-5-carboxamide
4-(5)-(3,3-Dimethyl-1-triazeno)imidazole-5(4)-carboxamide
4-(Dimethyltriazeno)imidazole-5-c arboxamide
4-(Dimethyltriazeno)imidazole-5-carboxamide
4-(or 5)-(3,3-Dimethyl-1-triazeno)imidazole-5(or 4)-carboxamide
4-(or 5)-(3,3-Dimethyl-1-triazeno)imidazole-5(or 4)-carboxamide
4-[(1E)-3,3-Dimethyltriaz-1-en-1-yl]-1H-imidazole-5-carboxamide
4-[3,3-dimethyltriaz-1-en-1-yl]-1H-imidazole-5-carboxamide
4342-03-4
5(or 4)-(dimethyltriazeno)imidazol e-4(or 5)-carboxamide
5(or 4)-(dimethyltriazeno)imidazole-4(or 5)-carboxamide
5-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide
5-(3,3-Dimethyl-1-triazenyl)-1H-imidazole-4-carboxamide
5-(3,3-Dimethyl-1-triazenyl)imidazole-4-carboxamide
5-(3,3-Dimethyltri azeno)imidazole-4-carboxamide
5-(3,3-Dimethyltriazeno)-imidazole-4-carbamide
5-(3,3-Dimethyltriazeno)imidazole-4-carboxamide
5-(3,3-dimethyltriaz-1-en-1-yl)-1H-imidazole-4-carboxamide
5-(Dimethyltriazeno)-4-imidazolecarboxamide
5-(Dimethyltriazeno)imidazole-4-carboxamide
5-(Dimethyltriazeno)imidazole-4-carboximide
5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide
5-[3,3-Dimethyl-1-triazenyl]imidazole-4-carboxamide
94361-71-4
AC1NQXVV
AC1NS01W
AC1NS4BN
AI3-52825
BPBio1_000428
BRD-K35520305-001-07-8
BSPBio_000388
BSPBio_002091
Biocarbazin
Biocarbazine
Biocarbazine R
C6H10N6O
CAS-891986
CCRIS 190
CHEBI:4305
CHEMBL476
CID5281007
CID5351166
CID5353562
Carboxamide, Dimethyl Imidazole
D00288
D003606
D2390_SIGMA
D3634
DB00851
DIC
DTCI
DTIC
DTIC Dome
DTIC, DTIC-Dome, Dacarbazine
DTIC-Dome
DTICDome
DTIE
Dacarbazin
Dacarbazina
Dacarbazine
Dacarbazine (JAN/USP/INN)
Dacarbazine [USAN:INN:BAN:JAN]
Dacarbazino
Dacarbazino [INN-Spanish]
Dacarbazinum
Dacarbazinum [INN-Latin]
 
Dacatic
Decarbazine
Deticene
Di-me-triazenoimidazolecarboxamide
Di-methyl-triazenoimidazolecarboxamide
Dimethyl Imidazole Carboxamide
Dimethyl Triazeno Imidazole Carboxamide
Dimethyltriazenoimidazolecarboxamide
DivK1c_000326
Dtic-Dome
Dtic-Dome (TN)
Dtic-dome (tn)
EINECS 224-396-1
HE1150000
HMS1569D10
HMS2090A20
HMS2091I20
HMS501A08
HSDB 3219
I06-2280
I14-1659
ICDMT
ICDT
IDI1_000326
Imidazole Carboxamide
Imidazole Carboxamide, Dimethyl
Imidazole carboxamide
KBio1_000326
KBio2_001364
KBio2_003932
KBio2_006500
KBio3_001311
KBioGR_000896
KBioSS_001364
LS-119
MLS001332543
MLS001332544
MolPort-003-666-153
MolPort-003-846-120
MolPort-006-709-420
NCGC00016986-01
NCGC00091861-01
NCGC00091861-02
NCGC00091861-03
NCGC00091861-04
NCI-C04717
NCI60_004053
NCIMech_000261
NINDS_000326
NIOSH/HE1150000
NPFAPI-05
NSC 45388
NSC-45388
NSC45388
Prestwick0_000574
Prestwick1_000574
Prestwick2_000574
Prestwick3_000574
Prestwick_904
S1221_Selleck
SMP2_000251
SMR000857131
SPBio_001075
SPBio_002607
SPECTRUM1500218
ST51014976
Spectrum2_001148
Spectrum3_000366
Spectrum4_000308
Spectrum5_000823
Spectrum_000884
UNII-7GR28W0FJI
WLN: T5M CNJ DVZ ENUNN1&1
dacarbazine
22
CrizotinibapprovedPhase 1, Phase 2104877399-52-511626560, 10366136, 10366137, 10366138, 10366139, 10366140, 10366141
Synonyms:
(R)-crizotinib
Crizotinib
 
Crizotinibum
PF-02341066
Xalkori
crizotinib
23Angiogenesis Modulating AgentsPhase 1, Phase 24185
24Piperazine citratePhase 1, Phase 224
25Angiogenesis InhibitorsPhase 1, Phase 24257
26Topoisomerase InhibitorsPhase 1, Phase 25069
27topoisomerase I inhibitorsPhase 1, Phase 21370
28AnthelminticsPhase 1, Phase 2446
29Anti-Infective AgentsPhase 1, Phase 222062
30Antineoplastic Agents, AlkylatingPhase 1, Phase 24603
31Antiparasitic AgentsPhase 1, Phase 22199
32Antimitotic AgentsPhase 1, Phase 25657
33Antineoplastic Agents, PhytogenicPhase 1, Phase 25602
34Alkylating AgentsPhase 1, Phase 24827
35AnticonvulsantsPhase 1, Phase 22695
36Protein Kinase InhibitorsPhase 1, Phase 23689
37
Citric Acidnutraceutical, vet_approvedPhase 1, Phase 2116077-92-9311
Synonyms:
2-Hydroxy-1,2,3-propanetricarboxylate
2-Hydroxy-1,2,3-propanetricarboxylic acid
2-Hydroxytricarballylic acid
3-Carboxy-3-hydroxypentane-1,5-dioate
3-Carboxy-3-hydroxypentane-1,5-dioic acid
Aciletten
Anhydrous citrate
Anhydrous citric acid
Chemfill
Citraclean
 
Citrate
Citretten
Citric acid
Citro
Citronensäure
E 330
Hydrocerol A
Kyselina citronova
Suby G
Uro-trainer
beta-Hydroxytricarballylate
beta-Hydroxytricarballylic acid
38CitrateNutraceuticalPhase 1, Phase 21160
39
TrioxsalenapprovedPhase 1413902-71-45585
Synonyms:
2',4,8-Trimethylpsoralen
4,5',8-Trimethylpsoralen
4,8,5'-Trimethylpsoralen
6-Hydroxy-beta,2,7-trimethyl-5-benzofuranacrylic acid, delta-lactone
Trimethylpsoralen
Trioxisaleno
 
Trioxsalen
Trioxysalen
Trioxysalene
Trioxysalenum
Trisoralen
trimethylpsoralen
trioxysalen
trisoralen
40
Verteporfinapproved, investigationalPhase 190129497-78-5
Synonyms:
Verteporfin
 
Verteporfina
Verteporfinum
Vertéporfine
41
Nicotinamideapproved, NutraceuticalPhase 191998-92-0936
Synonyms:
.beta.-Pyridinecarboxamide
11032-50-1
123574-63-0
1yc5
3 Pyridinecarboxamide
3-Carbamoylpyridine
3-Pyridinecarboxamide
3-Pyridinecarboxylic acid amide
37321-14-5
47865U_SUPELCO
55600-01-6
63748-44-7
72340_FLUKA
72340_SIGMA
72347_FLUKA
78731-47-2
98-92-0
A186B02E-6C70-4E54-9739-79398D439AAA
AC-907/25014114
AC1L1ACZ
AC1Q4ZFV
AI3-02906
Acid amide
Amid kyseliny nikotinove
Amid kyseliny nikotinove [Czech]
Amide PP
Aminicotin
Amixicotyn
Amnicotin
Astra Brand of Niacinamide
Austrovit PP
B 3, Vitamin
B3, Vitamin
BB_NC-2290
Benicot
C00153
C6H6N2O
CCRIS 1901
CHEBI:17154
CHEMBL1140
CID936
CPD000058212
D00036
D009536
DB02701
DEA No. 1405
Delonin Amide
Delonin amide
Dipegyl
Dipigyl
EINECS 202-713-4
EINECS 234-265-0
Endobion
Enduramide
Factor pp
HMS2052M21
HMS2090B05
HMS2093H03
HSDB 1237
Hansamid
I02-1741
I02-2250
InChI=1/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9
Inovitan PP
Jenapharm Brand of Niacinamide
Jenapharm, Nicotinsaureamid
LS-2051
MLS000069714
Mediatric
Merck Brand of Niacinamide
MolMap_000061
MolPort-001-783-876
N0078
N0636_SIGMA
N2142_SIGMA
N3376_SIGMA
N5535_SIAL
NAM
NCGC00093354-03
NCGC00093354-04
NSC 13128
NSC13128
NSC27452
Nandervit-N
Niacevit
Niacinamide
Niacinamide (USP)
Niacinamide Astra Brand
Niacinamide Jenapharm Brand
Niacinamide Merck Brand
 
Niacinamide Pharmagenix Brand
Niacinamide [USAN]
Niacinamide, Nicotinic acid amide, Nicotinamide
Niacotinamide
Niamide
Niavit PP
Nicamide
Nicamina
Nicamindon
Nicasir
Nicobion
Nicofort
Nicogen
Nicomidol
Nicosan 2
Nicosylamide
Nicota
Nicotamide
Nicotilamide
Nicotililamido
Nicotinamid
Nicotinamida
Nicotinamida [INN-Spanish]
Nicotinamide
Nicotinamide (JP15/INN)
Nicotinamide (Niacinamide)
Nicotinamide, niacin, vitamin B3
Nicotinamide-carbonyl-14C
Nicotinamidum
Nicotinamidum [INN-Latin]
Nicotine acid amide
Nicotine amide
Nicotinic acid amide
Nicotinic amide
Nicotinsaeureamid
Nicotinsaureamid
Nicotinsaureamid Jenapharm
Nicotinsaureamid [German]
Nicotol
Nicotylamide
Nicotylamidum
Nicovel
Nicovit
Nicovitina
Nicovitol
Nicozymin
Nictoamide
Nikasan
Nikazan
Niko-tamin
Nikotinamid
Nikotinsaeureamid
Nikotinsaeureamid [German]
Niocinamide
Niozymin
PP-Faktor
Papulex
Pelmin
Pelmine
Pelonin amide
Pharmagenix Brand of Niacinamide
Propamine A
Pyridine-3-carboxylic acid amide
S1899_Selleck
SAM001246860
SGCUT00176
SMR000058212
Savacotyl
UNII-25X51I8RD4
Vi-Nicotyl
Vi-noctyl
Vitamin B
Vitamin B (VAN)
Vitamin B 3
Vitamin B3 amide
Vitamin H1
Vitamin PP
WLN: T6NJ CVZ
Witamina PP
ZINC00005878
b-Pyridinecarboxamide
beta-Pyridinecarboxamide
bmse000281
m-(Aminocarbonyl)pyridine
nchembio.154-comp4
nchembio.73-comp6
niacin - Vitamin B3
niacinamide
nicotinamide
pyridine-3-carboxamide
to_000073
vitamin PP
42
Folic Acidapproved, nutraceutical, vet_approvedPhase 1439259-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
43
Niacinapproved, investigational, nutraceuticalPhase 192359-67-6938
Synonyms:
3-Carboxylpyridine
3-Carboxypyridine
3-Pyridinecarboxylate
3-Pyridinecarboxylic acid
3-Pyridylcarboxylate
3-Pyridylcarboxylic acid
3-carboxypyridine
Acide Nicotinique
Acido nicotinico
Acidum Nicotinicum
Akotin
Anti-pellagra vitamin
Apelagrin
Daskil
Efacin
Enduracin
Linic
M-Pyridinecarboxylic Acid
Niac
Niacin
Niacine
Niacor
Nicacid
Nicamin
Nicangin
 
Nico-Span
Nicobid
Nicocap
Nicodelmine
Nicolar
Niconacid
Nicosan 3
Nicotinate
Nicotinic Acid
Nicotinic acid
Nicotinipca
Nicyl
Nikotinsaeure
Nyclin
P.P. factor
PP Factor
Pellagra preventive factor
Pellagrin
Pelonin
Pyridine-beta-carboxylic acid
Slo-niacin
Vitamin B3
Wampocap
beta-Pyridinecarboxylic acid
pyridine-β-carboxylic acid
β-pyridinecarboxylic acid
44Dihematoporphyrin EtherPhase 141
45Photosensitizing AgentsPhase 1492
46VitaminsPhase 15282
47Vitamin B ComplexPhase 14337
48Trace ElementsPhase 16001
49MicronutrientsPhase 16001
50Nicotinic AcidsPhase 1923

Interventional clinical trials:

idNameStatusNCT IDPhase
1Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for CancerTerminatedNCT01132547Phase 3
2A Phase I Study of Mebendazole for the Treatment of Pediatric GliomasRecruitingNCT01837862Phase 1, Phase 2
3Crizotinib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell LymphomaActive, not recruitingNCT00939770Phase 1, Phase 2
4Photodynamic Therapy With Porfimer Sodium in Treating Patients With Refractory Brain TumorsUnknown statusNCT00002647Phase 1
5Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or LymphomaCompletedNCT01273090Phase 1
6Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in ChildrenNot yet recruitingNCT03043391Phase 1
7Efficacy of 68Ga-DOTATOC Positron Emission Tomography (PET) CT in Children and Young Adults With Brain TumorsWithdrawnNCT02194452

Search NIH Clinical Center for Pleomorphic Xanthoastrocytoma

Genetic Tests for Pleomorphic Xanthoastrocytoma

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Anatomical Context for Pleomorphic Xanthoastrocytoma

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MalaCards organs/tissues related to Pleomorphic Xanthoastrocytoma:

36
Brain, Temporal lobe, Spinal cord, Pineal, Cerebellum, Testes, Medulla oblongata

Publications for Pleomorphic Xanthoastrocytoma

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Articles related to Pleomorphic Xanthoastrocytoma:

(show top 50)    (show all 230)
idTitleAuthorsYear
1
Dabrafenib in BRAFV600-mutated anaplastic pleomorphic xanthoastrocytoma. (27781490)
2017
2
Cytologic features of pleomorphic xanthoastrocytoma, WHO grade II. A comparative study with glioblastoma. (28084690)
2017
3
Pleomorphic xanthoastrocytoma with anaplastic features: A rare case report and review of literature with reference to current management. (27366280)
2016
4
Melanosomal melanin pigment in pleomorphic xanthoastrocytoma, evidence for neuronal-glial origin: A case report with review of the literature. (27645472)
2016
5
Pediatric Pleomorphic Xanthoastrocytoma Treated With Surgical Resection Alone: Clinicopathologic Features. (27123665)
2016
6
Pleomorphic Xanthoastrocytoma with Anaplastic Features in the Tectal Region in a Young Adult Patient: A Case Report. (27521728)
2016
7
Glioblastoma multiforme versus pleomorphic xanthoastrocytoma with anaplastic features in the pathological diagnosis: a case report. (27449352)
2016
8
Combined pleomorphic xanthoastrocytoma-ganglioglioma with BRAF V600E mutation: case report. (27015517)
2016
9
BRAF-Mutated Pleomorphic Xanthoastrocytoma of the Spinal Cord with Eventual Anaplastic Transformation. (27956254)
2016
10
Angiomatous pleomorphic xanthoastrocytoma: a case report and literature review. (27506610)
2016
11
Pleomorphic xanthoastrocytoma arising from the suprasellar region: A report of two cases. (27452134)
2016
12
Primary anaplastic pleomorphic xanthoastrocytoma in adults. Case report and review of literature. (27639203)
2016
13
Perioperative Outcomes in Intracranial Pleomorphic Xanthoastrocytoma. (27183324)
2016
14
MGMT Promoter Methylation and BRAF V600E Mutations Are Helpful Markers to Discriminate Pleomorphic Xanthoastrocytoma from Giant Cell Glioblastoma. (27253461)
2016
15
Pleomorphic Xanthoastrocytoma with anaplastic features: a retrospective case series. (27476694)
2016
16
Activating NRF1-BRAF and ATG7-RAF1 fusions in anaplastic pleomorphic xanthoastrocytoma without BRAF p.V600E mutation. (27624885)
2016
17
BRAF V600E mutation: A treatable driver mutation in pleomorphic xanthoastrocytoma (PXA). (25811650)
2015
18
Cerebellar pleomorphic xanthoastrocytoma in a patient with neurofibromatosis type 1: a case report and literature review. (26261671)
2015
19
Primary Meningeal Pleomorphic Xanthoastrocytoma With Anaplastic Features: A Report of 2 Cases, One With BRAF(V600E) Mutation and Clinical Response to the BRAF Inhibitor Dabrafenib. (26352988)
2015
20
Spinal pleomorphic xanthoastrocytoma companied with periventricular tumor. (25755815)
2015
21
BRAF mutation and anaplasia may be predictive factors of progression-free survival in adult pleomorphic xanthoastrocytoma. (26454767)
2015
22
Anaplastic pleomorphic xanthoastrocytoma with spinal leptomeningeal spread at the time of diagnosis in an adult. (25934112)
2015
23
Does the occurrence of pleomorphic xanthoastrocytoma in the elderly carries a poor prognosis: A case report and review of literature. (25685227)
2014
24
Atypical teratoid/rhabdoid tumor arising in pleomorphic xanthoastrocytoma: a case report. (25268025)
2014
25
Pleomorphic Xanthoastrocytoma: Natural History and Long-term Follow-up. (25318587)
2014
26
Epithelioid glioblastoma arising from pleomorphic xanthoastrocytoma with the BRAF V600E mutation. (24894018)
2014
27
Molecular Pathology: SC18-1 INTERESTING CASE - ACTIONABLE MUTATION IN A CASE WITH A RECURRENT PLEOMORPHIC XANTHOASTROCYTOMA WITH ANAPLASTIC FEATURES. (25188122)
2014
28
Pleomorphic xanthoastrocytoma: report of two cases with unconventional clinical presentations. (25034704)
2014
29
Successful Treatment of a Progressive BRAF V600E-Mutated Anaplastic Pleomorphic Xanthoastrocytoma With Vemurafenib Monotherapy. (25092772)
2014
30
Composite pleomorphic xanthoastrocytoma-epithelioid glioneuronal tumor with BRAF V600E mutation - report of three cases. (24321241)
2014
31
Pleomorphic xanthoastrocytoma of the spinal cord: case report and literature review. (24495348)
2014
32
Pleomorphic Xanthoastrocytoma Within the Medulla Oblongata of a Young Dog. (24686391)
2014
33
Pleomorphic Xanthoastrocytoma of Childhood: MR Imaging and Diffusion MR Imaging Features. (24994821)
2014
34
Pleomorphic xanthoastrocytoma with anaplastic features: a case report. (24739844)
2014
35
Intraventricular pleomorphic xanthoastrocytoma: a case report. (25448222)
2014
36
Pleomorphic xanthoastrocytoma in a case of tuberous sclerosis. (25002765)
2014
37
DNA methylation alterations in grade II- and anaplastic pleomorphic xanthoastrocytoma. (24650279)
2014
38
Pleomorphic Xanthoastrocytoma Arising from Olfactory Groove: A Rare Location for a Rare Tumor. (25247328)
2014
39
Aggressive behavior and anaplasia in pleomorphic xanthoastrocytoma: a plea for a revision of the current WHO classification. (25054822)
2013
40
Case of pleomorphic xanthoastrocytoma with anaplastic features in the pineal gland. (23460303)
2013
41
BRAF-Mutated Pleomorphic Xanthoastrocytoma is Associated with Temporal Location, Reticulin Fiber Deposition and CD34 Expression. (24345274)
2013
42
Pleomorphic xanthoastrocytoma: long-term results of surgical treatment and analysis of prognostic factors. (23514331)
2013
43
The coexistence of pleomorphic xanthoastrocytoma and arteriovenous malformation. A case report. (24114645)
2013
44
Dysembryoplastic neuroepithelial tumors share with pleomorphic xanthoastrocytomas and gangliogliomas BRAF(V600E) mutation and expression. (23442159)
2013
45
Salvage therapy with BRAF inhibitors for recurrent pleomorphic xanthoastrocytoma: a retrospective case series. (23756728)
2013
46
Primary multicentric anaplastic pleomorphic xanthoastrocytoma with atypical features. (23827171)
2013
47
Nonanaplastic Pleomorphic Xanthoastrocytoma with Meningeal Dissemination Presenting with Bilateral Visual Loss. (23701304)
2013
48
Immunohistochemistry is highly sensitive and specific for detection of BRAF V600E mutation in pleomorphic xanthoastrocytoma. (24252190)
2013
49
Pleomorphic xanthoastrocytoma: magnetic resonance imaging findings in a series of cases with histopathological confirmation. (23249973)
2013
50
Prognostic factors and therapeutic outcomes in 22 patients with pleomorphic xanthoastrocytoma. (23908701)
2013

Variations for Pleomorphic Xanthoastrocytoma

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Clinvar genetic disease variations for Pleomorphic Xanthoastrocytoma:

5
id Gene Variation Type Significance SNP ID Assembly Location
1subset of 687 genes:AUTS2; BRAF; ELN; FOXP2; GLI3; SGCE; TBX20; TWIST1TMEM106B-BRAF fusiondeletionPathogenicGRCh37Chr 7, 12258147: 140494267

Copy number variations for Pleomorphic Xanthoastrocytoma from CNVD:

6
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
138148101135374737GainPleomorphic xanthoastrocytoma
215704021146944323GainPleomorphic xanthoastrocytoma
3157748212266877824107000Heterozygous deletio nPleomorphic xanthoastrocytoma
4158799213702807937104999Heterozygous deletio nPleomorphic xanthoastrocytoma
5158888213772751238987173Heterozygous deletio nPleomorphic xanthoastrocytoma
6161080221725778719792353Heterozygous deletio nPleomorphic xanthoastrocytoma
721704471158821424GainPleomorphic xanthoastrocytoma
824485291140273252Copy number LOHPleomorphic xanthoastrocytoma
925007791993014320420468Duplication with LOHPleomorphic xanthoastrocytoma
1025020192045177523120500Homozygous deletionPleomorphic xanthoastrocytoma

Expression for genes affiliated with Pleomorphic Xanthoastrocytoma

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Search GEO for disease gene expression data for Pleomorphic Xanthoastrocytoma.

Pathways for genes affiliated with Pleomorphic Xanthoastrocytoma

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GO Terms for genes affiliated with Pleomorphic Xanthoastrocytoma

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Biological processes related to Pleomorphic Xanthoastrocytoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cellular response to ionizing radiationGO:007147910.0MGMT, TP53
2cellular response to organic substanceGO:00713109.3MAP2, SYP

Sources for Pleomorphic Xanthoastrocytoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet