Aliases & Classifications for Pleural Disease

Aliases & Descriptions for Pleural Disease:

Name: Pleural Disease 12 14
Pleural Diseases 52 42 69
Disorder of Pleura 12 29
Non-Neoplastic Pleural Disorder 69
Non-Neoplastic Pleural Disease 12
Pleural Disorders 41

Classifications:



External Ids:

Disease Ontology 12 DOID:1532
MeSH 42 D010995
NCIt 47 C26859
SNOMED-CT 64 88075009
ICD10 33 J94.9 Q34.0
UMLS 69 C0032226

Summaries for Pleural Disease

MedlinePlus : 41 your pleura is a large, thin sheet of tissue that wraps around the outside of your lungs and lines the inside of your chest cavity. between the layers of the pleura is a very thin space. normally it's filled with a small amount of fluid. the fluid helps the two layers of the pleura glide smoothly past each other as your lungs breathe air in and out. disorders of the pleura include pleurisy - inflammation of the pleura that causes sharp pain with breathing pleural effusion - excess fluid in the pleural space pneumothorax - buildup of air or gas in the pleural space hemothorax - buildup of blood in the pleural space many different conditions can cause pleural problems. viral infection is the most common cause of pleurisy. the most common cause of pleural effusion is congestive heart failure. lung diseases, like copd, tuberculosis, and acute lung injury, cause pneumothorax. injury to the chest is the most common cause of hemothorax. treatment focuses on removing fluid, air, or blood from the pleural space, relieving symptoms, and treating the underlying condition. nih: national heart, lung, and blood institute

MalaCards based summary : Pleural Disease, also known as pleural diseases, is related to asbestosis and pleurisy, and has symptoms including pleuritic pain, coughing and dyspnea. An important gene associated with Pleural Disease is ADA (Adenosine Deaminase), and among its related pathways/superpathways are NF-kappaB Signaling and mTOR signaling pathway (KEGG). The drugs Azithromycin and Doxycycline have been mentioned in the context of this disorder. Affiliated tissues include heart and lung, and related phenotypes are cardiovascular system and homeostasis/metabolism

Disease Ontology : 12 A thoracic disease which may involve inflammation of pleura, collection of air within the pleural cavity, abnormal collection of pleural fluid, abnormal growths on the pleura (pleural tumor) and pleural plaques. The main causes of pleural diseases including pleural effusions are congestive heart failure, malignancy, parapneumonic infections and pulmonary embolism.

Wikipedia : 71 Pleural tumors may be benign (i.e. solitary fibromas) or malignant in nature. Pleural Mesothelioma is a... more...

Related Diseases for Pleural Disease

Diseases related to Pleural Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 97)
id Related Disease Score Top Affiliating Genes
1 asbestosis 29.8 ALB CRP TNF
2 pleurisy 11.0
3 chylothorax, congenital 10.7
4 intussusception 10.3 IL1B TNF
5 congenital dyserythropoietic anemia 10.3 ALB TNF
6 acquired thrombocytopenia 10.2 IL1B KNG1 TNF
7 autosomal dominant charcot-marie-tooth disease type 2 with giant axons 10.2 MPO TNF
8 tau syndrome 10.2 IL1B TNF
9 bile duct signet ring cell carcinoma 10.2 CHI3L1 CRP TNF
10 mikulicz disease 10.2 ALB IL1B TNF
11 functional gastric disease 10.2 ADA CRP TNF
12 ulcerative proctitis 10.2 ADA ALOX5 TNF
13 human immunodeficiency virus infectious disease 10.2 CRP IL1B TNF
14 benign neonatal seizures 10.2 CRP IL1B TNF
15 petrositis 10.2 ALB KLKB1 KNG1
16 pyloric stenosis, infantile hypertrophic, 2 10.2 CRP IL1B TNF
17 neuropathy 10.2 CRP IL1B TNF
18 histiocytoid hemangioma 10.2 ALB IL1B KNG1
19 patau syndrome 10.2 CRP IL1B TNF
20 atrophy of prostate 10.2 CRP IL1B TNF
21 blepharochalasis 10.2 CRP IL1B TNF
22 limb ischemia 10.2 CHI3L1 CRP TNF
23 infancy electroclinical syndrome 10.2 CRP IL1B TNF
24 endobronchial leiomyoma 10.2 CHI3L1 CRP TNF
25 pyelonephritis 10.1 CRP IL1B TNF
26 diabetic encephalopathy 10.1 CHI3L1 CRP TNF
27 plummer's disease 10.1 ALB CRP TNF
28 keratomalacia 10.1 CRP IL1B TNF
29 neovascular glaucoma 10.1 CRP KNG1 TNF
30 anterior foramen magnum meningioma 10.1 ADA ALB IL1B TNF
31 nephropathy with pretibial epidermolysis bullosa and deafness 10.1 ALB IL1B TNF
32 pancreas lymphoma 10.1 ADA CRP IL1B TNF
33 amelogenesis imperfecta 10.1 ALB CRP TNF
34 scalp dermatosis 10.1 CRP MPO TNF
35 breast apocrine carcinoma in situ 10.1 ALB IL1B MPO
36 respiratory system disease 10.1 CRP IL1B TNF
37 pigmentation disease 10.1 ALB IL1B TNF
38 synovium cancer 10.1 CRP IL1B TNF
39 familial nephrotic syndrome 10.1 ALB CRP TNF
40 spontaneous ocular nystagmus 10.1 ALOX5 IL1B TNF
41 osteonecrosis 10.1 CHI3L1 CRP IL1B TNF
42 pericholangitis 10.1 CRP MPO TNF
43 hypertropia 10.1 ADA ALB CRP TNF
44 goodpasture syndrome 10.1 ADA CRP IL1B TNF
45 dengue disease 10.1 CRP IL1B SLC22A4 TNF
46 cataract 10.1 ALB CRP IL1B TNF
47 choroiditis 10.1 ALB CRP IL1B TNF
48 rift valley fever 10.1 ALB CRP IL1B TNF
49 unilateral hypoactive labyrinth 10.1 ALB CRP IL1B TNF
50 colon adenocarcinoma 10.1 ALB CRP IL1B TNF

Graphical network of the top 20 diseases related to Pleural Disease:



Diseases related to Pleural Disease

Symptoms & Phenotypes for Pleural Disease

UMLS symptoms related to Pleural Disease:


pleuritic pain, coughing, dyspnea, snoring

MGI Mouse Phenotypes related to Pleural Disease:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.81 CRP FLCN FNIP1 IL1B KLKB1 MPO
2 homeostasis/metabolism MP:0005376 9.73 ADA ALB ALOX5 CRP FLCN FNIP1
3 immune system MP:0005387 9.36 ADA ALOX5 CHI3L1 CRP CXCL13 FLCN

Drugs & Therapeutics for Pleural Disease

Drugs for Pleural Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 413)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Azithromycin Approved Phase 4 83905-01-5 55185 53477736 447043
2
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 564-25-0 54671203
3
Lymecycline Approved Phase 4 992-21-2 5280963
4
Tetracycline Approved, Vet_approved Phase 4 60-54-8 5353990
5
Alprostadil Approved, Investigational Phase 4 745-65-3 149351
6
Everolimus Approved Phase 4,Phase 3,Phase 2 159351-69-6 6442177
7
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 22916-47-8 4189
8
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2 53123-88-9 5284616 6436030 46835353
9
Cefazolin Approved Phase 4,Phase 2,Phase 3 25953-19-9 656510 33255
10
Clindamycin Approved, Vet_approved Phase 4,Phase 2,Phase 3 18323-44-9 29029
11
Zoledronic acid Approved Phase 4,Phase 2 118072-93-8 68740
12
Amoxicillin Approved, Vet_approved Phase 4,Phase 2 26787-78-0 33613 2171
13
Ceftriaxone Approved Phase 4 73384-59-5 5479530 5361919
14
Oxacillin Approved Phase 4 66-79-5 6196
15
Cyclosporine Approved, Investigational, Vet_approved Phase 4,Phase 3 79217-60-0, 59865-13-3 5284373 6435893
16
Mycophenolate mofetil Approved, Investigational Phase 4 128794-94-5 5281078
17
Mycophenolic acid Approved Phase 4 24280-93-1 446541
18
Histamine Approved, Investigational Phase 4,Phase 2 75614-87-8, 51-45-6 774
19
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2 83-43-2 6741
20
Prednisolone Approved, Vet_approved Phase 4,Phase 2 50-24-8 5755
21
Benzocaine Approved Phase 4 1994-09-7, 94-09-7 2337
22
Bupivacaine Approved, Investigational Phase 4 2180-92-9, 38396-39-3 2474
23
Menthol Approved Phase 4,Early Phase 1 2216-51-5 16666
24
Ketotifen Approved Phase 4 34580-14-8, 34580-13-7 3827
25
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
26
Ofloxacin Approved Phase 4 82419-36-1 4583
27
Povidone-iodine Approved Phase 4,Phase 3 25655-41-8
28 tannic acid Approved, Nutraceutical Phase 4
29 Anti-Bacterial Agents Phase 4,Phase 2,Phase 3,Phase 1
30 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Phase 1
31 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Phase 1
32 Antitubercular Agents Phase 4,Phase 2,Phase 3
33 Antimalarials Phase 4,Phase 3,Phase 2
34 Antiparasitic Agents Phase 4,Phase 3,Phase 2
35 Antiprotozoal Agents Phase 4,Phase 3,Phase 2
36 Pulmonary Surfactants Phase 4,Phase 3
37 Respiratory System Agents Phase 4,Phase 3,Phase 2,Phase 1
38 Platelet Aggregation Inhibitors Phase 4
39 Vasodilator Agents Phase 4,Phase 2,Phase 3
40 Fibrinolytic Agents Phase 4,Phase 3,Phase 2,Phase 1
41 Plasminogen Phase 4,Phase 3,Phase 2,Phase 1
42 Tissue Plasminogen Activator Phase 4,Phase 3,Phase 2,Phase 1
43 Antifungal Agents Phase 4,Phase 3,Phase 2
44 Immunosuppressive Agents Phase 4,Phase 3,Phase 2,Phase 1
45 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2,Phase 1
46 Dermatologic Agents Phase 4,Phase 3,Phase 2,Phase 1
47 Neurotransmitter Agents Phase 4,Phase 2,Phase 3,Phase 1
48 Antiemetics Phase 4,Phase 3,Phase 2,Phase 1
49 Anti-Inflammatory Agents Phase 4,Phase 2,Phase 1
50 Antineoplastic Agents, Hormonal Phase 4,Phase 2

Interventional clinical trials:

(show top 50) (show all 602)
id Name Status NCT ID Phase
1 Improving Primary Spontaneous Pneumothorax (PSP) Treatment Techniques in VATS Unknown status NCT01463553 Phase 4
2 Comparison the Level of CTGF Protein and Related Cytokine in Pleural Effusion Unknown status NCT00313066 Phase 4
3 Correlation Among Sperm DNA Fragmentation, Genitourinary Infection by Mycoplasma in Male and the Pregnancy Outcomes After IUI in Their Partner Unknown status NCT01555047 Phase 4
4 Duration of Antibiotic Therapy in Community - Acquired Pneumonia Unknown status NCT01492387 Phase 4
5 Time to Eradication of Mycoplasma Genitalium and Chlamydia Trachomatis After Treatment Commenced Unknown status NCT01661985 Phase 4
6 Surfactant Administration During Spontaneous Breathing Unknown status NCT01329432 Phase 4
7 The Use of Prostaglandin E1 in Head and Neck Microsurgery Unknown status NCT00733434 Phase 4
8 The Study of Using Esophageal Pressure to Guide the PEEP Setting in Abdominal Hypertension Patients Who Undergoing Mechanical Ventilation Unknown status NCT01825304 Phase 4
9 Efficacy and Security of Intrapleurally Alteplase vs Urokinase for the Treatment of Complicated Parapneumonic Effusion and Empyema Completed NCT01246453 Phase 4
10 Impact of Aggressive Versus Standard Drainage Regimen Using a Long Term Indwelling Pleural Catheter Completed NCT00978939 Phase 4
11 Safety Profile of Iodopovidone as an Agent for Pleurodesis in Malignant Pleural Effusion Completed NCT01670786 Phase 4
12 Talc Pleurodesis in Patients With Recurrent Malignant Pleural Effusion Completed NCT00789087 Phase 4
13 Efficacy and Safety of Prophylactic Use of an Antibiotic for Medical Thoracoscopy Completed NCT02446782 Phase 4
14 Non-small Cell Lung Cancer Registry Completed NCT00099541 Phase 4
15 Comparison of the Ultra-low-dose Veo Algorithm With the Gold Standard Filtered Back Projection for Detecting Pulmonary Asbestos-related Conditions Completed NCT01955018 Phase 4
16 PleuraSeal Post Market Study (Europe) Completed NCT00704171 Phase 4
17 Comparison Between Amoxycillin/Clavulanic Acid and Oxacillin/Ceftriaxone for Community Acquired-pneumonia Completed NCT01166932 Phase 4
18 Everolimus in de Novo Heart Transplant Recipients Completed NCT01017029 Phase 4
19 Cystic Fibrosis and Totally Implantable Vascular Access Devices Completed NCT00244270 Phase 4
20 Early Intrapleural TPA Instillation Versus Late Recruiting NCT03167281 Phase 4
21 Ketotifen as a Treatment for Vascular Leakage During Dengue Fever Recruiting NCT02673840 Phase 4
22 The Effect of Chest Tubes Using Active Clearance Technology® on the Incidence of Postoperative Atrial Fibrillation Recruiting NCT02808897 Phase 4
23 Effects of Oral Steroid in Mycoplasma Pneumoniae Pneumonia Recruiting NCT02618057 Phase 4
24 Acute Effect of EPAP and Noninvasive Ventilation on Pulmonary Function and Lung Regional Ventilation on Bariatric Surgery Recruiting NCT02577744 Phase 4
25 Assessment of Intercostal Block Scheduling in Preventing Acute Surgical and Post-surgical Pain in Thoracoscopic Surgery Recruiting NCT02469610 Phase 4
26 Epidemiology and Outcome of Solitary Fibrous Tumors of the Pleura. Active, not recruiting NCT01694654 Phase 4
27 Evaluating Different Modalities for Pleural Adhesiolysis at Assuit University Hospital Not yet recruiting NCT03172052 Phase 4
28 Betadine Pleurodesis Via Tunneled Pleural Catheters Not yet recruiting NCT02975921 Phase 4
29 An Open Label, Phase IV Study Evaluating the Clinical Benefit, Safety and Pharmacokinetics of Raxibacumab in Subjects Exposed to Bacillus Anthracis Not yet recruiting NCT02177721 Phase 4
30 An Open Label Field Study of Anthim (Obiltoxaximab) in Subjects Exposed to B. Anthracis Not yet recruiting NCT03088111 Phase 4
31 Safety, Efficacy, and Side Effects Study of Interventional Cryotherapy in the Pleural Space("ICE PLS") Terminated NCT00747916 Phase 4
32 Pleural Abrasion Plus Minocycline Versus Apical Pleurectomy for Primary Spontaneous Pneumothorax Unknown status NCT00270751 Phase 2, Phase 3
33 Intrapleural Minocycline After Simple Aspiration for the Prevention of Primary Spontaneous Pneumothorax Unknown status NCT00418392 Phase 3
34 Pigtail Catheter Versus Chest Tube in the Management of Traumatic Pneumothorax Unknown status NCT01537289 Phase 3
35 Chest Tube Drainage or Thoracoscopic Surgery for Failed Aspiration of Spontaneous Pneumothorax Unknown status NCT00713362 Phase 2, Phase 3
36 Additional Minocycline Pleurodesis After Thoracoscopic Procedures for Primary Spontaneous Pneumothorax Unknown status NCT00154895 Phase 3
37 Intrapleural Urokinase for Retained Hemothorax Unknown status NCT01134237 Phase 3
38 Dornase Alfa and Urokinase for Kids With Pleural Empyema Unknown status NCT00502632 Phase 2, Phase 3
39 COlchicine for Prevention of the Post-pericardiotomy Syndrome and Post-operative Atrial Fibrillation (COPPS-2 Trial) Unknown status NCT01552187 Phase 3
40 Chest Tube After a Video-assisted Thoracoscopic Surgery Pulmonary Wedge Resection Unknown status NCT00841750 Phase 3
41 Efficacy and Safety of Sirolimus for Treating Lymphangioleiomyomatosis (LAM) Unknown status NCT00414648 Phase 3
42 ONCONASE Plus Doxorubicin Versus Doxorubicin Alone For Patients With Malignant Pleural or Peritoneal Mesothelioma Who Have Had No More Than One Prior Chemotherapy Regimen Unknown status NCT00003034 Phase 3
43 Use of an Oxidized Regenerated Cellulose After Hepatic Surgery Unknown status NCT01436721 Phase 2, Phase 3
44 Rigid Versus Semirigid Thoracoscopy in Diagnosing Pleural Diseases: a Randomized Study Completed NCT01366261 Phase 3
45 Cryobiopsy or Forceps Biopsy During Semirigid Thoracoscopy: a Comparative Study Completed NCT01475084 Phase 2, Phase 3
46 Efficacy of the Additional Mechanical Pleurodesis for Surgical Management of Primary Spontaneous Pneumothorax Completed NCT00615849 Phase 3
47 Bio-Seal Biopsy Track Plug for Reducing Pneumothorax Rates Post Lung Biopsy Procedure Completed NCT00562302 Phase 3
48 Role of Antibiotics to Reduce Infectious Complications in Tube Thoracotomy Management of Traumatic Hemopneumothorax Completed NCT01127880 Phase 2, Phase 3
49 Very Early Surfactant and NCPAP for Premature Infants With RDS Completed NCT00563641 Phase 3
50 A Prospective, Randomized Controlled Trial for a Rapid Pleurodesis Protocol for the Management of Pleural Effusions Completed NCT00758316 Phase 3

Search NIH Clinical Center for Pleural Disease

Cochrane evidence based reviews: pleural diseases

Genetic Tests for Pleural Disease

Genetic tests related to Pleural Disease:

id Genetic test Affiliating Genes
1 Abnormality of the Pleura 29

Anatomical Context for Pleural Disease

MalaCards organs/tissues related to Pleural Disease:

39
Heart, Lung

Publications for Pleural Disease

Articles related to Pleural Disease:

(show all 50)
id Title Authors Year
1
Role of respiratory-triggered diffusion-weighted MRI in the assessment of pleural disease. ( 27302493 )
2016
2
Diagnostic Utility of Pleural Fluid Cell Block versus Pleural Biopsy Collected by Flex-Rigid Pleuroscopy for Malignant Pleural Disease: A Single Center Retrospective Analysis. ( 27880851 )
2016
3
Malignant pleural disease is highly associated with subsequent peritoneal metastasis in patients with stage IV non-small cell lung cancer independent of oncogene status. ( 27133746 )
2016
4
Rapid on-site evaluation with the Hemacolor rapid staining method of medical thoracoscopy biopsy specimens for the management of pleural disease. ( 27080382 )
2016
5
Advances in pleural disease. ( 27246586 )
2016
6
Should primary tumor be resected for non-small cell lung cancer with malignant pleural disease unexpectedly found during operation?-a systemic review and meta-analysis. ( 27867560 )
2016
7
Advanced medical interventions in pleural disease. ( 27246597 )
2016
8
25-hydroxyvitamin D in malignant pleural disease: a prospective cohort study. ( 27502152 )
2016
9
Ultrasound-Guided Abrams Pleural Biopsy vs CT-Guided Tru-Cut Pleural Biopsy in Malignant Pleural Disease, a 3-Year Follow-up Study. ( 27540734 )
2016
10
IgG4-related disease in asbestos-related pleural disease. ( 26839697 )
2016
11
Erratum: Multidetector CT Findings and Differential Diagnoses of Malignant Pleural Mesothelioma and Metastatic Pleural Diseases in Korea. ( 27587973 )
2016
12
The importance of units specialising in pleural disease for postgraduate training. ( 27908379 )
2016
13
"Advanced medical interventions in pleural disease." Rahul Bhatnagar, John P. Corcoran, Fabien Maldonado, David Feller-Kopman, Julius Janssen, Philippe Astoul and Najib M. Rahman. Eur Respir Rev 2016; 25: 199-213. ( 27581835 )
2016
14
Reduced Port Thoracoscopic Surgery for Mediastinal and Pleural Disease: Experiences in a Single Institution. ( 27358509 )
2016
15
Accidental discovery of asbestos-related occupational pleural disease in unemployed carpenter: a healthcare safety net that needs mending. ( 26444343 )
2015
16
The impact of pleural disease on the management of advanced ovarian cancer. ( 25969350 )
2015
17
A modified experimental model of malignant pleural disease induced by lung Lewis carcinoma (LLC) cells. ( 26373420 )
2015
18
A randomised controlled trial of intravenous zoledronic acid in malignant pleural disease: a proof of principle pilot study. ( 25781025 )
2015
19
The past, current and future of diagnosis and management of pleural disease. ( 26807281 )
2015
20
Physical activity in people with asbestos related pleural disease and dust-related interstitial lung disease: An observational study. ( 26048393 )
2015
21
A pilot study of autofluorescence in the diagnosis of pleural disease. ( 25411951 )
2015
22
Rapid progression of pleural disease due to exposure to Libby amphibole: "Not your grandfather's asbestos related disease". ( 24898907 )
2014
23
Mediastinectomy for management of chronic pyogranulomatous pleural disease in dogs. ( 24686857 )
2014
24
Physician-based ultrasound-guided biopsy for diagnosing pleural disease. ( 24832701 )
2014
25
Autofluorescence thoracoscopy in pleural disease: does it have clinical relevance? ( 24856077 )
2014
26
IgG4-related pleural disease presenting as a massive bilateral effusion. ( 24992134 )
2014
27
Advances in pleural disease management including updated procedural coding. ( 25091756 )
2014
28
Progress means change: reflections on two articles about pleural disease. ( 23720696 )
2013
29
A rare cause of pleural disease. ( 23487832 )
2013
30
Advances in the management of pleural disease. ( 24138694 )
2013
31
Levels of YKL-40 in pleural effusions and blood from patients with pulmonary or pleural disease. ( 22480951 )
2012
32
Management of spontaneous pneumothorax: British Thoracic Society Pleural Disease Guideline 2010. ( 20696690 )
2010
33
Crystal-storing histiocytosis presenting with pleural disease. ( 20459543 )
2010
34
Clinical value of fluorodeoxyglucose-positron emission tomography/computed tomography in differentiation of malignant mesothelioma from asbestos-related benign pleural disease: an observational pilot study. ( 19875971 )
2009
35
Managing Pleural Disease in Acute Medicine ( II ) : Spontaneous Pneumothorax. ( 21611569 )
2008
36
Pleural disease in lymphangioleiomyomatosis. ( 16716823 )
2006
37
Clinical year in review II: pulmonary infections, diagnostic imaging, pleural diseases, and neuromuscular disease. ( 16222034 )
2005
38
The additional risk of malignant mesothelioma in former workers and residents of Wittenoom with benign pleural disease or asbestosis. ( 16169910 )
2005
39
Pleural disease in silicosis: pleural thickening, effusion, and invagination. ( 16040925 )
2005
40
Resolution of residual pleural disease according to time course in tuberculous pleurisy during and after the termination of antituberculosis medication. ( 16304268 )
2005
41
Lymphocytes in pleural disease. ( 15928502 )
2005
42
Cystatin C of pleural effusion as a novel diagnostic aid in pleural diseases of different aetiologies. ( 11869179 )
2002
43
Diagnostic principles in pleural disease. ( 9042652 )
1997
44
Clear cell sarcoma: an extremely rare cause of pleural disease. ( 9426110 )
1997
45
Lung crackle characteristics in patients with asbestosis, asbestos-related pleural disease and left ventricular failure using a time-expanded waveform analysis--a comparative study. ( 8029512 )
1994
46
Pulmonary function in asbestosis and asbestos-related pleural disease. ( 8472663 )
1993
47
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 36-1990. A 42-year-old woman with pleural disease, chylous ascites, and lymphadenopathy. ( 2385269 )
1990
48
Loculated hemopneumothorax of a major fissure in patients with COPD and associated pleural disease. ( 2097999 )
1990
49
Asbestos-related pleural disease and asbestosis: a comparison of CT and chest radiography. ( 3257311 )
1988
50
CT features of an unusual hypervascular lung carcinoma complicating chronic asbestosis related pleural disease. ( 2985664 )
1985

Variations for Pleural Disease

Expression for Pleural Disease

Search GEO for disease gene expression data for Pleural Disease.

Pathways for Pleural Disease

Pathways related to Pleural Disease according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 12.16 ALOX5 IL1B MPO TNF
2
Show member pathways
12.09 FLCN FNIP1 FNIP2 TNF
3
Show member pathways
11.43 ALB ALOX5 CRP IL1B MPO TNF
4 11.11 KNG1 MPO TNF
5 11.01 IL1B KLKB1 TNF
6 10.34 IL1B MPO TNF

GO Terms for Pleural Disease

Cellular components related to Pleural Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.7 ALB ALOX5 CHI3L1 CRP CXCL13 IL1B
2 extracellular space GO:0005615 9.4 ADA ALB ALOX5 CHI3L1 CRP CXCL13

Biological processes related to Pleural Disease according to GeneCards Suite gene sharing:

(show all 18)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of protein phosphorylation GO:0001934 9.71 FLCN FNIP1 IL1B TNF
2 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.67 FNIP1 FNIP2 TNF
3 negative regulation of lipid catabolic process GO:0050995 9.58 IL1B TNF
4 negative regulation of growth of symbiont in host GO:0044130 9.57 MPO TNF
5 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.56 IL1B TNF
6 TOR signaling GO:0031929 9.55 FLCN FNIP1
7 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.54 IL1B TNF
8 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.52 IL1B TNF
9 positive regulation of chemokine biosynthetic process GO:0045080 9.51 IL1B TNF
10 negative regulation of lipid storage GO:0010888 9.48 CRP TNF
11 regulation of establishment of endothelial barrier GO:1903140 9.46 IL1B TNF
12 positive regulation of fever generation GO:0031622 9.43 IL1B TNF
13 sequestering of triglyceride GO:0030730 9.37 IL1B TNF
14 positive regulation of protein complex assembly GO:0031334 9.33 FNIP1 FNIP2 TNF
15 regulation of pro-B cell differentiation GO:2000973 9.32 FLCN FNIP1
16 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.26 IL1B TNF
17 regulation of protein phosphorylation GO:0001932 9.26 FLCN FNIP1 FNIP2 TNF
18 inflammatory response GO:0006954 9.23 ALOX5 CHI3L1 CRP CXCL13 IL1B KLKB1

Molecular functions related to Pleural Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 chaperone binding GO:0051087 9.13 ALB FNIP1 FNIP2
2 ATPase inhibitor activity GO:0042030 8.62 FNIP1 FNIP2

Sources for Pleural Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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