MCID: PLR005
MIFTS: 43

Pleuropneumonia

Categories: Respiratory diseases

Aliases & Classifications for Pleuropneumonia

MalaCards integrated aliases for Pleuropneumonia:

Name: Pleuropneumonia 12 42 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:14319
MeSH 42 D011001
SNOMED-CT 64 60485005
UMLS 69 C0032241

Summaries for Pleuropneumonia

Disease Ontology : 12 A pneumonia accompanied by inflammation of the pleura and accumulation of pus in the pleural space caused by bacteria.

MalaCards based summary : Pleuropneumonia is related to adult-onset distal myopathy due to vcp mutation and bartholin's gland adenoma. An important gene associated with Pleuropneumonia is SNORD50A (Small Nucleolar RNA, C/D Box 50A), and among its related pathways/superpathways are Akt Signaling and Toll-like Receptor Signaling Pathway. The drugs Azithromycin and Doxycycline have been mentioned in the context of this disorder. Affiliated tissues include testes, lung and colon, and related phenotypes are hematopoietic system and immune system

Wikipedia : 72 Pleuropneumonia is inflammation of the lungs and pleura, pleurisy being the inflammation of the pleura... more...

Related Diseases for Pleuropneumonia

Diseases related to Pleuropneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 121)
id Related Disease Score Top Affiliating Genes
1 adult-onset distal myopathy due to vcp mutation 10.7 HBB HBD
2 bartholin's gland adenoma 10.7 HBB HBD
3 hepatic infarction 10.6 HBB HBD
4 cyanosis, transient neonatal 10.6 HBB HBD
5 glucosephosphate dehydrogenase deficiency 10.6 HBB HBD
6 bile duct cystadenoma 10.5 HBB HBD
7 central epithelioid sarcoma 10.5 HBB HBD
8 vulvar disease 10.4 CD79A IRAK4
9 cutis laxa 10.3 CD79A CXCL9
10 alcoholic neuropathy 10.3 CD40LG CD79A
11 calloso-genital dysplasia 10.3 CD40LG CD79A
12 variola major 10.3 CD40LG CD79A
13 mu chain disease 10.3 CD40LG CD79A
14 rabies 10.3 CD40LG CD79A
15 familial retinoblastoma 10.3 CD40LG CD79A
16 anti-basement membrane glomerulonephritis 10.3 CD40LG CD79A
17 microinvasive cervical squamous cell carcinoma 10.3 CD40LG CD79A
18 fetal erythroblastosis 10.2 CD40LG CD79A
19 spinal canal and spinal cord meningioma 10.2 CD40LG CD79A
20 trichostrongyloidiasis 10.2 CD40LG CD79A
21 leukodystrophy 10.2 CD40LG CD79A
22 retinal microaneurysm 10.2 CD40LG CD79A
23 heart septal defect 10.2 CD40LG CD79A
24 cryptorchidism arachnodactyly mental retardation 10.2 CD40LG CD79A
25 acute kidney tubular necrosis 10.2 CD40LG CD79A
26 secretory meningioma 10.2 CD40LG CD79A
27 hodgkin's lymphoma, nodular sclerosis 10.2 CD40LG CD79A
28 imperforate oropharynx-costo vetebral anomalies 10.2 CD40LG CD79A
29 malignant otitis externa 10.2 CD40LG CD79A
30 transient hypogammaglobulinemia 10.2 CD40LG CD79A
31 benign epilepsy with centrotemporal spikes 10.2 CD40LG CD79A
32 tongue cancer 10.2 CD40LG CD79A
33 hydrops of gallbladder 10.2 CD40LG CD79A
34 diabetic angiopathy 10.2 CD40LG CD79A
35 rosacea conjunctivitis 10.2 CD40LG CD79A
36 viral meningitis 10.2 CD40LG CD79A
37 heart fibrosarcoma 10.2 CD40LG CD79A
38 alopecia areata 10.2 CD40LG CD79A
39 kidney carcinoma in situ 10.1 CD40LG CD79A
40 cardiac tuberculosis 10.1 CD40LG CD79A
41 dumping syndrome 10.1 CD40LG CD79A
42 leiomyosarcoma 10.1 CD40LG CD79A
43 periarthritis 10.1 CD40LG CD79A
44 generalized atherosclerosis 10.1 CD40LG CD79A
45 vitamin k deficiency hemorrhagic disease 10.1 CD79A FCGR3A FCGR3B
46 cerebral neuroblastoma 10.1 CD40LG CD79A
47 motor neuron disease 10.1 CD40LG PLAT
48 milk allergy 10.1 CD40LG IL1R1
49 pancreatic vasoactive intestinal peptide producing tumor 10.1 CD40LG CD79A
50 rett syndrome, congenital variant 10.1 FCGR3A FCGR3B

Graphical network of the top 20 diseases related to Pleuropneumonia:



Diseases related to Pleuropneumonia

Symptoms & Phenotypes for Pleuropneumonia

MGI Mouse Phenotypes related to Pleuropneumonia:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.85 CD40LG CD79A FCGR3B GGT1 IL1R1 IRAK1
2 immune system MP:0005387 9.65 PLAT CD40LG CD79A FCGR3B GGT1 IL1R1
3 skeleton MP:0005390 9.23 CD40LG COL18A1 FCGR3B GGT1 IL1R1 IRAK3

Drugs & Therapeutics for Pleuropneumonia

Drugs for Pleuropneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 101)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Azithromycin Approved Phase 4,Phase 3,Phase 2 83905-01-5 55185 53477736 447043
2
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 564-25-0 54671203
3
Lymecycline Approved Phase 4 992-21-2 5280963
4
Tetracycline Approved, Vet_approved Phase 4 60-54-8 5353990
5
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
6
Ofloxacin Approved Phase 4 82419-36-1 4583
7
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
8
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
9 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Early Phase 1
10 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Early Phase 1
11 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Early Phase 1
12 Antimalarials Phase 4,Phase 3,Phase 2
13 Antiparasitic Agents Phase 4,Phase 3,Phase 2
14 Antiprotozoal Agents Phase 4,Phase 3,Phase 2
15 Antitubercular Agents Phase 4,Phase 3,Phase 2
16 Anti-Inflammatory Agents Phase 4
17 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3,Phase 2
18 Gastrointestinal Agents Phase 4,Phase 2
19 Peripheral Nervous System Agents Phase 4
20 Autonomic Agents Phase 4
21 Cytochrome P-450 CYP1A2 Inhibitors Phase 4
22 Renal Agents Phase 4,Phase 2
23 Topoisomerase Inhibitors Phase 4
24 Antiemetics Phase 4
25 Antineoplastic Agents, Hormonal Phase 4
26 glucocorticoids Phase 4
27 Hormone Antagonists Phase 4
28 Hormones Phase 4
29 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
30 Methylprednisolone acetate Phase 4
31 Methylprednisolone Hemisuccinate Phase 4
32 Neuroprotective Agents Phase 4
33 Prednisolone acetate Phase 4
34 Prednisolone hemisuccinate Phase 4
35 Prednisolone phosphate Phase 4
36 Protective Agents Phase 4
37 Carboxymethylcellulose Sodium Phase 4
38 Cathartics Phase 4
39 Laxatives Phase 4
40
Clarithromycin Approved Phase 3,Phase 2 81103-11-9 84029
41
Josamycin Approved Phase 3 16846-24-5 5282165
42
Ceftriaxone Approved Phase 3 73384-59-5 5479530 5361919
43
Cefixime Approved Phase 3 79350-37-1 54362 5362065
44 Cytochrome P-450 CYP3A Inhibitors Phase 3,Phase 2
45 Cephalosporins Phase 3
46 beta-Lactams Phase 3
47 Lactams Phase 3
48
Tinidazole Approved, Investigational Phase 2 19387-91-8 5479
49
Basiliximab Approved, Investigational Phase 2 152923-56-3, 179045-86-4
50
Infliximab Approved Phase 2 170277-31-3

Interventional clinical trials:

(show all 46)

id Name Status NCT ID Phase Drugs
1 Correlation Among Sperm DNA Fragmentation, Genitourinary Infection by Mycoplasma in Male and the Pregnancy Outcomes After IUI in Their Partner Unknown status NCT01555047 Phase 4
2 Time to Eradication of Mycoplasma Genitalium and Chlamydia Trachomatis After Treatment Commenced Unknown status NCT01661985 Phase 4 Azithromycin;Doxycycline;lymecycline
3 Duration of Antibiotic Therapy in Community - Acquired Pneumonia Unknown status NCT01492387 Phase 4
4 Microorganism in Overactive Bladder Patients Completed NCT00883818 Phase 4 azithromycin, doxycycline
5 AZithromycin Against pLacebo in Exacerbations of Asthma Completed NCT01444469 Phase 4 Zithromax;Placebo
6 Effects of Oral Steroid in Mycoplasma Pneumoniae Pneumonia Recruiting NCT02618057 Phase 4 Prednisolone;Levofloxacin
7 Chronic Bladder Pain Syndrome in Women: Can Doxycycline Help? A Prospective Study Terminated NCT01879930 Phase 4 doxycycline;placebo
8 Clarithromycin Prophylaxis in Preterm Infants Colonisation With Ureaplasma Urealyticum and Mycoplasma Hominis Unknown status NCT01652118 Phase 3 clarithromycin treatment for prophylaxis of bronchopulmonary dysplasia;Saline
9 Mycoplasma Genitalium Antibiotic Susceptibility and Treatment (MEGA) Completed NCT00358462 Phase 3 Azithromycin;Doxycycline
10 Antibiotic Treatment of Gulf War Veterans' Illnesses Completed NCT00007735 Phase 3 Doxycycline (200mg/day) or Placebo
11 Reduction of Spontaneous Prematurity by Antibiotic Treatment (Josamycin) Completed NCT00718705 Phase 3 Josamycin;Placebo
12 Comparative Study of Ceftaroline vs. Ceftriaxone in Adults With Community-Acquired Pneumonia Completed NCT00509106 Phase 3 Ceftaroline fosamil for Injection;Ceftriaxone;Placebo
13 Comparative Study of Ceftaroline vs. Ceftriaxone in Adult Subjects With Community-Acquired Pneumonia Completed NCT00621504 Phase 3 Ceftaroline fosamil for Injection;IV Ceftriaxone;Placebo;Clarithromycin
14 Empiric Therapy of Mucopurulent Cervicitis (MPC) Terminated NCT01072136 Phase 3 Azithromycin;Cefixime
15 Antibiotic Treatment Trial for the PANDAS/PANS Phenotype Completed NCT01617083 Phase 2 Azithromycin;Placebo
16 NGU: Doxycycline (Plus or Minus Tinidazole) Versus Azithromycin (Plus or Minus Tinidazole) Completed NCT00322465 Phase 2 Tinidazole;Doxycycline;Azithromycin
17 Mesenchymal Stem Cells as First Treatment Line for Resistant Acute Graft Versus Host Disease Recruiting NCT02770430 Phase 2 conventional treatment
18 Pharmacokinetic Study of Clarithromycin in Very Low Birth Weight (VLBW) Terminated NCT01851954 Phase 2 Clarithromycin
19 Mecillinam for Treatment of Genital Chlamydia Infection Terminated NCT02083276 Phase 2 Pivmecillinamhydrochlorid
20 NSAIDs Treatment in Children With Pleuropneumonia Unknown status NCT01586299 Ibuprofen;Acetaminophen
21 Evaluation of a Serology Diagnostic Kit for the Detection of Genital Mycoplasma in Pregnancy Unknown status NCT01281319
22 Prevalence and Clinical Significance of Co-infection of Mycoplasma Pneumoniae in Patients With Pulmonary Tuberculosis Unknown status NCT00926601
23 Effectiveness Study of Integrative Treatment for Pediatric Community Acquired Pneumonia Unknown status NCT02362906 Xiyanping injection;wind-heat formula granules;phlegm-heat formula granules;Fu-xiong San;second generation cephalosporin;Erythromycin;Azithromycin
24 300 Antibody Diagnostic Test Kit Unknown status NCT01646411
25 Detection of Mycoplasma Pneumoniae Completed NCT02511262
26 Chlamydia and Mycoplasma in Coronary Artery Disease Completed NCT00561028
27 Randomized Controlled Trial of Doxycycline to Prevent Acquisition of Mycoplasma Pneumoniae in an Outbreak Setting Completed NCT00207584 Doxycycline treatment
28 The Optimization of Mycoplasm Pneumonia Antibiotic Therapy Completed NCT01259141 Moxifloxacin;Cephalosporins and azithromycin
29 Colonization of the Female Urethra With Mycoplasma Hominis, Ureaplasma Urealyticum, Chlamydia Trachomatis, or Neisseria Gonorrhea in Patients With Lower Urinary Tract Symptoms Completed NCT01559623
30 Etiology of Community Acquired Pneumonia Completed NCT00471757
31 Community-Acquired Pneumonia (CAP) Surveillance Completed NCT01416506
32 Rewarding Sexually Transmitted Infection (STI) Prevention and Control in Tanzania Completed NCT00922038
33 Clinical Efficacy of Roxithromycin in Men With Chronic Prostatitis/Chronic Pelvic Pain Syndrome Completed NCT01843946
34 Levofloxacin in Bacterial Rhinosinussitis Completed NCT02712502 Levofloxacin;Amoxicillin-Potassium Clavulanate Combination
35 Microbiologic Findings of Acute Facial Palsy in Children Completed NCT01537952
36 Use of Non Steroidal Antiinflammatory Drugs in Patients With Community Acquired Pneumonia Completed NCT02523885
37 Methylprednisolone for Children With Severe Mycoplasma Pneumoniae Pneumonia (MCMP) Recruiting NCT02303587 methylprednisolone
38 Etiology Study of Kawasaki Disease Recruiting NCT00154596
39 Assessment of Pharyngeal Carriage of Microorganisms Responsible for Transmissible Acute Respiratory Infections in HAJJ Pilgrims. Recruiting NCT02868541
40 Prevalence of Sexually Transmitted Infections Among People Attending the Sexual Assault Centre in Oslo, Norway. Recruiting NCT03132389
41 Collecting and Storing Tissue From Young Patients With Cancer Recruiting NCT00898755
42 Evaluation of the Use of the Colli-Pee Device to Collect First-void Urine for Molecular Detection of STIs Active, not recruiting NCT02552914
43 Personalized Immunotherapeutic for Antibiotic-resistant Infection Enrolling by invitation NCT02508584 Early Phase 1
44 Comparative Autoantibody and Immunologic Cell Marker Study Enrolling by invitation NCT02422875
45 Methylprednisolone Pulse Macrolide Therapy for Refractory Mycoplasma Pneumoniae Pneumonia in Children Terminated NCT01217099 methylprednisolone;azithromycin
46 A Polymerase Chain Reaction (PCR) - Based Method to Improve Antibiotic Prescribing for Pneumonia Withdrawn NCT00867841

Search NIH Clinical Center for Pleuropneumonia

Cochrane evidence based reviews: pleuropneumonia

Genetic Tests for Pleuropneumonia

Anatomical Context for Pleuropneumonia

MalaCards organs/tissues related to Pleuropneumonia:

39
Testes, Lung, Colon, Liver, Prostate, Kidney, B Cells

Publications for Pleuropneumonia

Articles related to Pleuropneumonia:

(show top 50) (show all 561)
id Title Authors Year
1
Factors Associated with Survival in 97 Horses with Septic Pleuropneumonia. ( 28271546 )
2017
2
The value of molecular techniques to diagnose Ureaplasma urealyticum and Nocardia farcinica Pleuropneumonia in a Patient with Diffuse large B-Cell Lymphoma. ( 28951103 )
2017
3
Policy analysis for delivery of contagious bovine pleuropneumonia control strategies in sub-Saharan Africa. ( 28926016 )
2017
4
Ultrasonographic findings in goats with contagious caprine pleuropneumonia caused by Mycoplasma capricolum subsp. capripneumoniae. ( 28830505 )
2017
5
Kinetics of single and dual infection of pigs with swine influenza virus and Actinobacillus pleuropneumoniae. ( 28284596 )
2017
6
Lung lesion score system in cattle: proposal for contagious bovine pleuropneumonia. ( 28951993 )
2017
7
B cell cross-epitope of Propionibacterium acnes and Actinobacillus pleuropneumonia selected by phage display library can efficiently protect from Actinobacillus pleuropneumonia infection. ( 28622855 )
2017
8
Thoracic splenosis mimicking a pleuropneumonia: A case report. ( 28723778 )
2017
9
Contagious caprine pleuropneumonia: The first isolation and molecular characterization of Mycoplasma capricolum subsp. capripneumoniae in the Kingdom of Saudi Arabia. ( 28111131 )
2017
10
Seroprevalence and Distribution of Contagious Bovine Pleuropneumonia in Ethiopia: Update and Critical Analysis of 20 Years (1996-2016) Reports. ( 28702460 )
2017
11
Pharmacokinetic/pharmacodynamic integration and modelling of oxytetracycline for the porcine pneumonia pathogens Actinobacillus pleuropneumoniae and Pasteurella multocida. ( 28090673 )
2017
12
A meta-analysis of contagious caprine pleuropneumonia (CCPP) in Ethiopia. ( 26943994 )
2016
13
Contagious bovine pleuropneumonia: Seroprevalence and risk factors in Western Oromia, Ethiopia. ( 27247066 )
2016
14
Development of a Novel Cocktail Enzyme-Linked Immunosorbent Assay and a Field-Applicable Lateral-Flow Rapid Test for Diagnosis of Contagious Bovine Pleuropneumonia. ( 27053669 )
2016
15
Morphological characterization and immunohistochemical detection of the proinflammatory cytokines IL-1I^, IL-17A, and TNF-I+ in lung lesions associated with contagious bovine pleuropneumonia. ( 26837619 )
2016
16
Capsular polysaccharide from Mycoplasma mycoides subsp. mycoides shows potential for protection against contagious bovine pleuropneumonia. ( 27496744 )
2016
17
A contagious bovine pleuropneumonia outbreak on a research farm in Ethiopia, and its dynamics over an eight-month period. ( 28332650 )
2016
18
Qualitative and quantitative impacts assessment of contagious bovine pleuropneumonia in Fulani pastoral herds of North-central Nigeria: The associated socio-cultural factors. ( 27237398 )
2016
19
Coinfection by Ureaplasma spp., Photobacterium damselae and an Actinomyces-like microorganism in a bottlenose dolphin (Tursiops truncatus) with pleuropneumonia stranded along the Adriatic coast of Italy. ( 27033917 )
2016
20
Complete Genome Sequence of Mycoplasma mycoides subsp. mycoides T1/44, a Vaccine Strain against Contagious Bovine Pleuropneumonia. ( 27081135 )
2016
21
Recombinant Mycoplasma mycoides proteins elicit protective immune responses against contagious bovine pleuropneumonia. ( 26964722 )
2016
22
Community-acquired pleuropneumonia in children: Bacteriological and therapeutic challenges. ( 27704513 )
2016
23
The Association of Fibrinous Pleural Effusion with Survival and Complications in Horses with Pleuropneumonia (2002-2012): 74 Cases. ( 26259510 )
2015
24
Non-haemolytic Mannheimia haemolytica as a cause of pleuropneumonia and septicemia in a calf. ( 26344042 )
2015
25
Mathematical modelling of the transmission dynamics of contagious bovine pleuropneumonia reveals minimal target profiles for improved vaccines and diagnostic assays. ( 25668725 )
2015
26
Isolation and Phylogenetic Characterization of Streptococcus halichoeri from a European Badger (Meles meles) with Pyogranulomatous Pleuropneumonia. ( 25678424 )
2015
27
Seroprevalence of contagious bovine pleuropneumonia (CBPP) in Mali. ( 25433650 )
2015
28
Sero-prevalence of Contagious Bovine Pleuropneumonia (CBPP) in bulls originated from Borena pastoral area of Southern Ethiopia. ( 25863957 )
2015
29
Participatory Epidemiology of Ethnoveterinary Practices Fulani Pastoralists Used to Manage Contagious Bovine Pleuropneumonia and Other Cattle Ailments in Niger State, Nigeria. ( 26464953 )
2015
30
Therapeutic effect of Chinese patent medicine "Wuhuanghu" on porcine infectious pleuropneumonia and its acute and subchronic toxicity as well as evaluation of safety pharmacology. ( 26245812 )
2015
31
Quantitative risk assessment of entry of contagious bovine pleuropneumonia through live cattle imported from northwestern Ethiopia. ( 26427634 )
2015
32
Serological prevalence of contagious bovine pleuropneumonia in agro-pastoral areas of Nigeria. ( 25894821 )
2015
33
Update on Bacterial Pneumonia and Pleuropneumonia in the Adult Horse. ( 25600453 )
2015
34
Sero-positivity and associated risk factors for contagious bovine pleuropneumonia under two cattle production systems in North Central Nigeria. ( 26563271 )
2015
35
Analysis of immune responses to recombinant proteins from strains of Mycoplasma mycoides subsp. mycoides, the causative agent of contagious bovine pleuropneumonia. ( 26384697 )
2015
36
Abattoir surveillance demonstrates contagious bovine pleuropneumonia is widespread in Tanzania. ( 26315150 )
2015
37
Streptococcus equi subsp zooepidemicus pleuropneumonia and peritonitis in a dromedary camel (Camelus dromedarius) calf in North America. ( 26176731 )
2015
38
Proteomic characterization of pleural effusion, a specific host niche of Mycoplasma mycoides subsp. mycoides from cattle with contagious bovine pleuropneumonia (CBPP). ( 26476145 )
2015
39
Whole-Genome Sequencing of Mycoplasma mycoides subsp. mycoides Italian Strain 57/13, the Causative Agent of Contagious Bovine Pleuropneumonia. ( 25814605 )
2015
40
A large-scale genomic approach affords unprecedented resolution for the molecular epidemiology and evolutionary history of contagious caprine pleuropneumonia. ( 26149260 )
2015
41
The Use of Recombinant Tissue Plasminogen Activator (rTPA) in The Treatment of Fibrinous Pleuropneumonia in Horses: 25 Cases (2007-2012). ( 26256909 )
2015
42
Efficacy of vaccination against Actinobacillus pleuropneumoniae in two Belgian farrow-to-finish pig herds with a history of chronic pleurisy. ( 24552670 )
2014
43
Blood values of captive beira antelope (Dorcatragus megalotis) prior to and during an outbreak of fibrinous pleuropneumonia syndrome (FPPS). ( 25632657 )
2014
44
High antibody titres against predicted Mycoplasma surface proteins do not prevent sequestration in infected lung tissue in the course of experimental contagious bovine pleuropneumonia. ( 24880898 )
2014
45
An international collaborative study to determine the prevalence of contagious caprine pleuropneumonia by monoclonal antibody-based cELISA. ( 24565080 )
2014
46
Characterization of the in vitro core surface proteome of Mycoplasma mycoides subsp. mycoides, the causative agent of contagious bovine pleuropneumonia. ( 24332827 )
2014
47
Comparison of in vivo and in vitro properties of capsulated and noncapsulated variants of Mycoplasma mycoides subsp. mycoides strain AfadAc: a potential new insight into the biology of contagious bovine pleuropneumonia. ( 25123820 )
2014
48
Oral immunization against porcine pleuropneumonia using the cubic phase of monoolein and purified toxins of Actinobacillus pleuropneumoniae. ( 25446832 )
2014
49
Control of contagious bovine pleuropneumonia: knowledge, attitudes, perceptions and practices in Narok district of Kenya. ( 24768437 )
2014
50
Fatal transmission of contagious caprine pleuropneumonia to an Arabian oryx (Oryx leucoryx). ( 25069622 )
2014

Variations for Pleuropneumonia

Expression for Pleuropneumonia

Search GEO for disease gene expression data for Pleuropneumonia.

Pathways for Pleuropneumonia

Pathways related to Pleuropneumonia according to GeneCards Suite gene sharing:

(show all 17)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.25 CD40LG CXCL9 IL1R1 IRAK1 IRAK3 IRAK4
2
Show member pathways
12.71 CXCL9 IRAK1 IRAK3 IRAK4 MYD88
3
Show member pathways
12.55 CD40LG IL1R1 IRAK1 IRAK3 IRAK4 MYD88
4
Show member pathways
12.48 CD40LG IL1R1 IRAK1 IRAK3 IRAK4 MYD88
5
Show member pathways
12.28 IRAK1 IRAK3 IRAK4 MYD88
6 12.23 CD40LG CD79A IRAK1 IRAK3 IRAK4 MYD88
7
Show member pathways
12.14 IL1R1 IRAK1 IRAK3 IRAK4 MYD88
8
Show member pathways
12.06 IL1R1 IRAK1 IRAK3 IRAK4 MYD88
9 12.05 FCGR3A FCGR3B IRAK1 IRAK4 MYD88
10
Show member pathways
11.94 IL1R1 IRAK1 IRAK3 IRAK4 MYD88
11 11.6 IRAK1 IRAK4 MYD88
12 11.55 CD40LG FCGR3A FCGR3B
13 11.38 CD40LG HBB MYD88
14
Show member pathways
11.37 CD40LG FCGR3A FCGR3B IRAK1 IRAK4 MYD88
15 11.33 CD40LG IL1R1 IRAK1 IRAK4 MYD88
16 11.19 IL1R1 IRAK1 IRAK3 MYD88
17 11.07 IL1R1 IRAK1 MYD88

GO Terms for Pleuropneumonia

Cellular components related to Pleuropneumonia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 9.46 CD40LG CD79A CXCL9 FCGR3A
2 extracellular space GO:0005615 9.23 CD40LG CELA3B COL18A1 CXCL9 GGT1 HBB
3 hemoglobin complex GO:0005833 8.96 HBB HBD

Biological processes related to Pleuropneumonia according to GeneCards Suite gene sharing:

(show all 15)
id Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.92 CD40LG CXCL9 FCGR3A FCGR3B IL1R1
2 response to lipopolysaccharide GO:0032496 9.78 CXCL9 IRAK1 IRAK3 MYD88
3 cytokine-mediated signaling pathway GO:0019221 9.72 IL1R1 IRAK1 IRAK3 IRAK4 MYD88
4 regulation of inflammatory response GO:0050727 9.69 GGT1 IL1R1 MYD88
5 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.65 CD40LG IRAK1 IRAK3 IRAK4 MYD88
6 positive regulation of smooth muscle cell proliferation GO:0048661 9.63 IRAK1 IRAK4 MYD88
7 JNK cascade GO:0007254 9.61 IRAK1 IRAK4 MYD88
8 toll-like receptor signaling pathway GO:0002224 9.58 IRAK1 IRAK4 MYD88
9 positive regulation of endothelial cell apoptotic process GO:2000353 9.55 CD40LG COL18A1
10 oxygen transport GO:0015671 9.54 HBB HBD
11 toll-like receptor 9 signaling pathway GO:0034162 9.54 IRAK1 IRAK4 MYD88
12 response to peptidoglycan GO:0032494 9.49 IRAK3 MYD88
13 response to interleukin-1 GO:0070555 9.46 IL1R1 IRAK1 IRAK3 MYD88
14 MyD88-dependent toll-like receptor signaling pathway GO:0002755 9.26 IRAK1 IRAK3 IRAK4 MYD88
15 interleukin-1-mediated signaling pathway GO:0070498 8.92 IL1R1 IRAK1 IRAK3 IRAK4

Molecular functions related to Pleuropneumonia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 interleukin-1 receptor binding GO:0005149 9.16 IRAK4 MYD88
2 oxygen transporter activity GO:0005344 8.96 HBB HBD
3 IgG binding GO:0019864 8.62 FCGR3A FCGR3B

Sources for Pleuropneumonia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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