MCID: PLR005
MIFTS: 36

Pleuropneumonia malady

Summaries for Pleuropneumonia

Sources:
8Disease Ontology, 64Wikipedia, 33MalaCards
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Disease Ontology:8 A pneumonia accompanied by inflammation of the pleura and accumulation of pus in the pleural space caused by bacteria.

MalaCards: Pleuropneumonia, also known as pleurobronchopneumonia, is related to hepatitis c and urethritis. An important gene associated with Pleuropneumonia is PRF1 (perforin 1 (pore forming protein)), and among its related pathways are Activation of DNA fragmentation factor and Granzyme Pathway. The compounds sugar phosphate and phosphodiester have been mentioned in the context of this disorder. Affiliated tissues include skin, kidney and lymph node.

Wikipedia:64 Contagious bovine pleuropneumonia (CBPP - also known as lung plague), is a contagious bacterial disease... more...

Aliases & Classifications for Pleuropneumonia

Sources:
8Disease Ontology, 61UMLS, 57SNOMED-CT, 35MeSH
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Aliases & Descriptions:

pleuropneumonia 8 61
pleurobronchopneumonia 8


External Ids:

Disease Ontology8 DOID:14319
SNOMED-CT57 60485005
MeSH35 D011001

Related Diseases for Pleuropneumonia

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Pleuropneumonia:



Diseases related to pleuropneumonia

Clinical Features for Pleuropneumonia

Drugs & Therapeutics for Pleuropneumonia

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Pleuropneumonia

Anatomical Context for Pleuropneumonia

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33MalaCards
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MalaCards organs/tissues related to Pleuropneumonia:

33
Skin, Kidney, Lymph node, Lung, T cells, B lymphoblasts, B cells

Animal Models for Pleuropneumonia or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Pleuropneumonia

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51PubMed
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Articles related to Pleuropneumonia:

(show top 50)    (show all 509)
idTitleAuthorsYear
1
Performance evaluation of two serological tests for contagious bovine pleuropneumonia (CBPP) detection in an enzootic area using a Bayesian framework. (22528527)
2012
2
Plasma levels of TNF-I+, IFN-I^, IL-4 and IL-10 during a course of experimental contagious bovine pleuropneumonia. (22533922)
2012
3
Combination fibrinolytic therapy in the treatment of chronic septic pleuropneumonia in a Thoroughbred gelding. (22928684)
2012
4
Intrapleural fibrinolytic therapy in the management of septic pleuropneumonia in a horse. (19411687)
2009
5
Analysis of cellular responses to Mycoplasma mycoides subsp. mycoides small colony biotype associated with control of contagious bovine pleuropneumonia. (18073095)
2008
6
Impact of Mycoplasma bovis infection on serosurveillance for contagious bovine pleuropneumonia. (19029111)
2008
7
Fever of unknown origin secondary to occult pleuropneumonia. (16627096)
2006
8
A serological investigation into contagious caprine pleuropneumonia (CCPP) in Ethiopia. (15729893)
2005
9
Contagious bovine pleuropneumonia vaccines and control strategies: recent data. (15742622)
2004
10
The genome sequence of Mycoplasma mycoides subsp. mycoides SC type strain PG1T, the causative agent of contagious bovine pleuropneumonia (CBPP). (14762060)
2004
11
Isolation of Streptococcus canis from a Japanese raccoon dog with fibrinous pleuropneumonia. (14584580)
2003
12
Molecular epidemiology of contagious bovine pleuropneumonia by multilocus sequence analysis of Mycoplasma mycoides subspecies mycoides biotype SC strains. (12713894)
2003
13
Effects of pentoxifylline on inflammatory cytokine expression and acute pleuropneumonia in swine. (11999342)
2002
14
Genetic evolution of Mycoplasma capricolum subsp. capripneumoniae strains and molecular epidemiology of contagious caprine pleuropneumonia by sequencing of locus H2. (11844618)
2002
15
Monoclonal antibody differentiation of Mycoplasma mycoides subsp. mycoides small-colony strains causing contagious bovine pleuropneumonia from less important large-colony strains. (10799473)
2000
16
Contagious bovine pleuropneumonia. A reassessment of the efficacy of vaccines used in Africa. (11193704)
2000
17
Severe pleuropneumonia without a cough and myocarditis with mixed mycoplasma infection. (9007792)
1996
18
Variations in urinary gamma glutamyl transferase/urinary creatinine ratio in horses with or without pleuropneumonia treated with gentamicin. (7556049)
1995
19
Pleural effusion associated with acute and chronic pleuropneumonia and pleuritis secondary to thoracic wounds in horses: 43 cases (1982-1992). (7744650)
1994
20
Improvements in the diagnosis of contagious bovine pleuropneumonia through the use of monoclonal antibodies. (7691274)
1993
21
Treatment and complications of pleuropneumonia. (2015808)
1991
22
Serodiagnosis of pleuropneumonia using enzyme-linked immunosorbent assay with capsular polysaccharide antigens of Actinobacillus pleuropneumoniae serotypes 1, 2, 5 and 7. (2249177)
1990
23
Blood gas stability and hematological changes in experimentally-induced acute porcine pleuropneumonia. (2914231)
1989
24
Immunogenicity of oil-based contagious bovine pleuropneumonia vaccine in cattle. (3799020)
1986
25
Evaluation of a Killed Vaccine Against Porcine Pleuropneumonia Due to Haemophilus pleuropneumoniae. (17422508)
1985
26
Porcine pleuropneumonia associated with Haemophilus pleuropneumoniae serotype 3 in Quebec. (6523705)
1984
27
Immunisation of goats against contagious caprine pleuropneumonia using sonicated antigens of F-38 strain of mycoplasma. (6718817)
1984
28
Effect of some cultural factors on T1 broth vaccine for contagious bovine pleuropneumonia. (6353721)
1983
29
Vaccination against pleuropneumonia of pigs caused by Haemophilus pleuropneumoniae. (7225995)
1981
30
A mycoplasma from acute contagious caprine pleuropneumonia in Kenya. (936303)
1976
31
Passive immunity to contagious bovine pleuropneumonia. (766133)
1975
32
Contagious bovine pleuropneumonia in African buffalo (Syncerus caffer). (4945496)
1970
33
Contagious bovine pleuropneumonia vaccination in East Africa. (5394154)
1969
34
Contagious bovine pleuropneumonia aspects of eradication in Australia. (5393992)
1969
35
Increased sensitivity of the complement fixation test for contagious bovine pleuropneumonia on sera preserved with phenol. (5751958)
1968
36
Study on the virulence of contagious bovine pleuropneumonia organism (Assam strain) on subcutaneous pathogenicity test. (5751813)
1968
37
Contagious bovine pleuropneumonia. The keeping properties of the V5 vaccine used in Australia. (5651974)
1968
38
Studies on avian pleuropneumonia-like organisms. IV. Raising PPLO-free flock by antibiotic dip treatment. (6068468)
1967
39
Mycoplasma from contagious caprine pleuropneumonia. (4964006)
1967
40
A note on inactivated contagious bovine pleuropneumonia vaccines. (5976395)
1966
41
Rapid method for demonstrating intracellular pleuropneumonia-like organisms in a strain of hamster kidney cells (BHK 21 C13). (4163559)
1966
42
Pleuropneumonia-like organisms and related forms. (5318445)
1965
43
PORCINE CONTAGIOUS PLEUROPNEUMONIA. II. STUDIES OF THE PATHOGENICITY OF THE ETIOLOGICAL AGENT, HEMOPHILUS PLEUROPNEUMONIAE. (14129708)
1964
44
LIPID COMPOSITION AND SYNTHESIS IN THE PLEUROPNEUMONIA-LIKE ORGANISM MYCOPLASMA GALLISEPTICUM. (14071787)
1963
45
A STUDY OF CELL WALL COMPONENTS OF PLEUROPNEUMONIA-LIKE ORGANISMS. (14101013)
1963
46
Cultivation of pleuropneumonia-like organisms (PPLO) from tissue cultures. (13948823)
1962
47
Acetokinase reaction in several pleuropneumonia-like organisms. (14019260)
1962
48
Cultivation of pleuropneumonia-like organisms on membrane discs for microscopic examination. (13865002)
1962
49
Cultivation of pleuropneumonia like organisms in Reiter's disease, including one instance of laboratory cross infection. (14413019)
1960
50
The isolation and cultivation of a filterable form resembling pleuropneumonia-like organisms from the human dental pulp: report of a case. (13796783)
1960

Genetic Variations for Pleuropneumonia

Expression for genes affiliated with Pleuropneumonia

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Pleuropneumonia

Search GEO for disease gene expression data for Pleuropneumonia.

Pathways for genes affiliated with Pleuropneumonia

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54Reactome, 52QIAGEN, 50PharmGKB
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Pathways related to Pleuropneumonia according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.8PRF1, APEX1
2
Hide members
9.8PRF1, APEX1
39.3GGT1, APEX1

Compounds for genes affiliated with Pleuropneumonia

Sources:
45Novoseek, 29IUPHAR, 11DrugBank, 24HMDB
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Compounds related to Pleuropneumonia according to GeneCards/GeneDecks:

(show all 18)
idCompoundScoreTop Affiliating Genes
1sugar phosphate4510.1TBP, APEX1
2phosphodiester4510.0TBP, APEX1
3penicillin459.9APEX1, TF
4tbps45 2910.9TBP, TF
5tocopherol459.9TBP, TF
6sodium dodecylsulfate459.7KRT17, TBP, APEX1
7agar459.5APEX1, TF, PRF1
8histidine459.5TBP, PRF1, APEX1
9gentamicin45 1110.5TF, GGT1
10antipyrine45 1110.4TF, GGT1
11diethyl dithiocarbamate459.3GGT1, APEX1
12alpha tocopherol459.2TF, TBP, GGT1
13thyroxine45 2410.2GGT1, TBP, TF
14gsno459.0GGT1, APEX1
15n acetylcysteine458.9APEX1, TF, GGT1
16adenine45 11 2410.8GGT1, TBP, TF, APEX1
17iron45 249.8APEX1, TF, TBP, GGT1
18ascorbic acid45 249.8GGT1, TF, APEX1

GO Terms for genes affiliated with Pleuropneumonia

Products for genes affiliated with Pleuropneumonia

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Sources for Pleuropneumonia

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet