MCID: PLR005
MIFTS: 43

Pleuropneumonia malady

Categories: Respiratory diseases

Aliases & Classifications for Pleuropneumonia

Aliases & Descriptions for Pleuropneumonia:

Name: Pleuropneumonia 12 42 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:14319
MeSH 42 D011001
SNOMED-CT 64 60485005
UMLS 69 C0032241

Summaries for Pleuropneumonia

Disease Ontology : 12 A pneumonia accompanied by inflammation of the pleura and accumulation of pus in the pleural space caused by bacteria.

MalaCards based summary : Pleuropneumonia is related to adult-onset multiple mitochondrial dna deletion syndrome due to dguok deficiency and middle ear adenoma. An important gene associated with Pleuropneumonia is SNORD50A (Small Nucleolar RNA, C/D Box 50A), and among its related pathways/superpathways are Akt Signaling and IL-2 Pathway. The drugs Azithromycin and Doxycycline have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and kidney, and related phenotypes are hematopoietic system and immune system

Wikipedia : 71 Pleuropneumonia is inflammation of the lungs and pleura, pleurisy being the inflammation of the pleura... more...

Related Diseases for Pleuropneumonia

Diseases related to Pleuropneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 85)
id Related Disease Score Top Affiliating Genes
1 adult-onset multiple mitochondrial dna deletion syndrome due to dguok deficiency 10.3 HBB HBD
2 middle ear adenoma 10.3 HBB HBD
3 alcoholic neuropathy 10.2 CD40LG CD79A
4 camptodactyly vertebral fusion 10.2 CD40LG CD79A
5 spinal polio 10.2 CD40LG CD79A
6 rabies 10.2 CD40LG CD79A
7 unilateral retinoblastoma 10.1 CD40LG CD79A
8 mesangial proliferative glomerulonephritis 10.1 CD40LG CD79A
9 secernentea infections 10.1 CD79A CXCL9
10 delta chain disease 10.1 CD40LG CD79A
11 discitis 10.1 CD40LG CD79A
12 spinal canal and spinal cord meningioma 10.1 CD40LG CD79A
13 trichostrongyloidiasis 10.1 CD40LG CD79A
14 colloid adenoma 10.1 CD40LG CD79A
15 heart septal defect 10.1 CD40LG CD79A
16 cutaneous polyarteritis nodosa 10.1 CD40LG CD79A
17 mild pre-eclampsia 10.1 CD40LG CD79A
18 retinal microaneurysm 10.1 CD40LG CD79A
19 recombinase activating gene 2 deficiency 10.1 FCGR3A FCGR3B
20 pediatric meningioma 10.1 CD40LG CD79A
21 tonsil cancer 10.1 CD40LG CD79A
22 vitamin k deficiency hemorrhagic disease 10.1 CD79A FCGR3A FCGR3B
23 indomethacin antenatal infection 10.1 CD40LG CD79A
24 malignant visceral pleura tumor 10.1 GGT1 WARS
25 hyperlipoproteinemia type iii 10.1 CD79A CXCL9
26 hypertrophic elongation of cervix 10.1 CD40LG CD79A GGT1
27 postcricoid region cancer 10.1 CD40LG CD79A
28 mu chain disease 10.1 CD40LG CD79A MYD88
29 colonic benign neoplasm 10.1 CD40LG CD79A MYD88
30 arteriosclerosis 10.1 CD40LG CD79A MYD88
31 beach ear 10.1 CD40LG CD79A
32 akinetopsia 10.1 CD40LG CD79A MYD88
33 acute kidney tubular necrosis 10.1 CD40LG CD79A
34 hallucinogen dependence 10.0 CD40LG CD79A MYD88
35 bulbospinal polio 10.0 CD40LG FCGR3A FCGR3B
36 pneumonia 10.0
37 atheroembolism of kidney 10.0 CD40LG CD79A
38 anterior foramen magnum meningioma 10.0 CD40LG CD79A FCGR3A
39 temtamy syndrome 10.0 CD40LG CD79A CXCL9
40 sertoli-leydig cell tumor 10.0 CD40LG CD79A PLAT
41 venezuelan equine encephalitis 10.0 CD40LG CD79A CXCL9
42 partial sensory epilepsy 10.0 CD40LG CD79A
43 pseudoarthrosis 9.9 CD40LG CD79A GGT1
44 megacolon 9.9 CD40LG CD79A WARS
45 type 2 papillary adenoma of the kidney 9.9 CD40LG CD79A FCGR3A FCGR3B
46 influenza 9.9
47 rhinitis 9.8
48 atrophic rhinitis 9.8
49 urethritis 9.8
50 arthritis 9.8

Graphical network of the top 20 diseases related to Pleuropneumonia:



Diseases related to Pleuropneumonia

Symptoms & Phenotypes for Pleuropneumonia

MGI Mouse Phenotypes related to Pleuropneumonia:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.7 CD40LG CD79A FCGR3B GGT1 IL1R1 IRAK1
2 immune system MP:0005387 9.32 CD40LG CD79A FCGR3B GGT1 IL1R1 IRAK1

Drugs & Therapeutics for Pleuropneumonia

Drugs for Pleuropneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 101)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Azithromycin Approved Phase 4,Phase 3,Phase 2 83905-01-5 55185 53477736 447043
2
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 564-25-0 54671203
3
Lymecycline Approved Phase 4 992-21-2 5280963
4
Tetracycline Approved, Vet_approved Phase 4 60-54-8 5353990
5
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
6
Ofloxacin Approved Phase 4 82419-36-1 4583
7
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
8
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
9 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Early Phase 1
10 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Early Phase 1
11 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Early Phase 1
12 Antimalarials Phase 4,Phase 3,Phase 2
13 Antiparasitic Agents Phase 4,Phase 3,Phase 2
14 Antiprotozoal Agents Phase 4,Phase 3,Phase 2
15 Antitubercular Agents Phase 4,Phase 3,Phase 2
16 Anti-Inflammatory Agents Phase 4
17 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3,Phase 2
18 Gastrointestinal Agents Phase 4,Phase 2
19 Peripheral Nervous System Agents Phase 4
20 Autonomic Agents Phase 4
21 Cytochrome P-450 CYP1A2 Inhibitors Phase 4
22 Renal Agents Phase 4,Phase 2
23 Topoisomerase Inhibitors Phase 4
24 Antiemetics Phase 4
25 Antineoplastic Agents, Hormonal Phase 4
26 glucocorticoids Phase 4
27 Hormone Antagonists Phase 4
28 Hormones Phase 4
29 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
30 Methylprednisolone acetate Phase 4
31 Methylprednisolone Hemisuccinate Phase 4
32 Neuroprotective Agents Phase 4
33 Prednisolone acetate Phase 4
34 Prednisolone hemisuccinate Phase 4
35 Prednisolone phosphate Phase 4
36 Protective Agents Phase 4
37 Carboxymethylcellulose Sodium Phase 4
38 Cathartics Phase 4
39 Laxatives Phase 4
40
Clarithromycin Approved Phase 3,Phase 2 81103-11-9 84029
41
Josamycin Approved Phase 3 16846-24-5 5282165
42
Ceftriaxone Approved Phase 3 73384-59-5 5479530 5361919
43
Cefixime Approved Phase 3 79350-37-1 54362 5362065
44 Cytochrome P-450 CYP3A Inhibitors Phase 3,Phase 2
45 Cephalosporins Phase 3
46 beta-Lactams Phase 3
47 Lactams Phase 3
48
Tinidazole Approved, Investigational Phase 2 19387-91-8 5479
49
Basiliximab Approved, Investigational Phase 2 152923-56-3, 179045-86-4
50
Infliximab Approved Phase 2 170277-31-3

Interventional clinical trials:

(show all 46)
id Name Status NCT ID Phase
1 Correlation Among Sperm DNA Fragmentation, Genitourinary Infection by Mycoplasma in Male and the Pregnancy Outcomes After IUI in Their Partner Unknown status NCT01555047 Phase 4
2 Time to Eradication of Mycoplasma Genitalium and Chlamydia Trachomatis After Treatment Commenced Unknown status NCT01661985 Phase 4
3 Duration of Antibiotic Therapy in Community - Acquired Pneumonia Unknown status NCT01492387 Phase 4
4 Microorganism in Overactive Bladder Patients Completed NCT00883818 Phase 4
5 AZithromycin Against pLacebo in Exacerbations of Asthma Completed NCT01444469 Phase 4
6 Effects of Oral Steroid in Mycoplasma Pneumoniae Pneumonia Recruiting NCT02618057 Phase 4
7 Chronic Bladder Pain Syndrome in Women: Can Doxycycline Help? A Prospective Study Terminated NCT01879930 Phase 4
8 Clarithromycin Prophylaxis in Preterm Infants Colonisation With Ureaplasma Urealyticum and Mycoplasma Hominis Unknown status NCT01652118 Phase 3
9 Mycoplasma Genitalium Antibiotic Susceptibility and Treatment (MEGA) Completed NCT00358462 Phase 3
10 Antibiotic Treatment of Gulf War Veterans' Illnesses Completed NCT00007735 Phase 3
11 Reduction of Spontaneous Prematurity by Antibiotic Treatment (Josamycin) Completed NCT00718705 Phase 3
12 Comparative Study of Ceftaroline vs. Ceftriaxone in Adults With Community-Acquired Pneumonia Completed NCT00509106 Phase 3
13 Comparative Study of Ceftaroline vs. Ceftriaxone in Adult Subjects With Community-Acquired Pneumonia Completed NCT00621504 Phase 3
14 Empiric Therapy of Mucopurulent Cervicitis (MPC) Terminated NCT01072136 Phase 3
15 Antibiotic Treatment Trial for the PANDAS/PANS Phenotype Completed NCT01617083 Phase 2
16 NGU: Doxycycline (Plus or Minus Tinidazole) Versus Azithromycin (Plus or Minus Tinidazole) Completed NCT00322465 Phase 2
17 Mesenchymal Stem Cells as First Treatment Line for Resistant Acute Graft Versus Host Disease Recruiting NCT02770430 Phase 2
18 Pharmacokinetic Study of Clarithromycin in Very Low Birth Weight (VLBW) Terminated NCT01851954 Phase 2
19 Mecillinam for Treatment of Genital Chlamydia Infection Terminated NCT02083276 Phase 2
20 NSAIDs Treatment in Children With Pleuropneumonia Unknown status NCT01586299
21 Evaluation of a Serology Diagnostic Kit for the Detection of Genital Mycoplasma in Pregnancy Unknown status NCT01281319
22 Prevalence and Clinical Significance of Co-infection of Mycoplasma Pneumoniae in Patients With Pulmonary Tuberculosis Unknown status NCT00926601
23 Effectiveness Study of Integrative Treatment for Pediatric Community Acquired Pneumonia Unknown status NCT02362906
24 300 Antibody Diagnostic Test Kit Unknown status NCT01646411
25 Detection of Mycoplasma Pneumoniae Completed NCT02511262
26 Chlamydia and Mycoplasma in Coronary Artery Disease Completed NCT00561028
27 Randomized Controlled Trial of Doxycycline to Prevent Acquisition of Mycoplasma Pneumoniae in an Outbreak Setting Completed NCT00207584
28 The Optimization of Mycoplasm Pneumonia Antibiotic Therapy Completed NCT01259141
29 Colonization of the Female Urethra With Mycoplasma Hominis, Ureaplasma Urealyticum, Chlamydia Trachomatis, or Neisseria Gonorrhea in Patients With Lower Urinary Tract Symptoms Completed NCT01559623
30 Community-Acquired Pneumonia (CAP) Surveillance Completed NCT01416506
31 Rewarding Sexually Transmitted Infection (STI) Prevention and Control in Tanzania Completed NCT00922038
32 Clinical Efficacy of Roxithromycin in Men With Chronic Prostatitis/Chronic Pelvic Pain Syndrome Completed NCT01843946
33 Levofloxacin in Bacterial Rhinosinussitis Completed NCT02712502
34 Microbiologic Findings of Acute Facial Palsy in Children Completed NCT01537952
35 Use of Non Steroidal Antiinflammatory Drugs in Patients With Community Acquired Pneumonia Completed NCT02523885
36 Methylprednisolone for Children With Severe Mycoplasma Pneumoniae Pneumonia (MCMP) Recruiting NCT02303587
37 Etiology Study of Kawasaki Disease Recruiting NCT00154596
38 Assessment of Pharyngeal Carriage of Microorganisms Responsible for Transmissible Acute Respiratory Infections in HAJJ Pilgrims. Recruiting NCT02868541
39 Collecting and Storing Tissue From Young Patients With Cancer Recruiting NCT00898755
40 Etiology of Community Acquired Pneumonia Active, not recruiting NCT00471757
41 Evaluation of the Use of the Colli-Pee Device to Collect First-void Urine for Molecular Detection of STIs Active, not recruiting NCT02552914
42 Personalized Immunotherapeutic for Antibiotic-resistant Infection Enrolling by invitation NCT02508584 Early Phase 1
43 Comparative Autoantibody and Immunologic Cell Marker Study Enrolling by invitation NCT02422875
44 Prevalence of Sexually Transmitted Infections Among People Attending the Sexual Assault Centre in Oslo, Norway. Not yet recruiting NCT03132389
45 Methylprednisolone Pulse Macrolide Therapy for Refractory Mycoplasma Pneumoniae Pneumonia in Children Terminated NCT01217099
46 A Polymerase Chain Reaction (PCR) - Based Method to Improve Antibiotic Prescribing for Pneumonia Withdrawn NCT00867841

Search NIH Clinical Center for Pleuropneumonia

Cochrane evidence based reviews: pleuropneumonia

Genetic Tests for Pleuropneumonia

Anatomical Context for Pleuropneumonia

MalaCards organs/tissues related to Pleuropneumonia:

39
Lung, Testes, Kidney, T Cells, Skin, Lymph Node

Publications for Pleuropneumonia

Articles related to Pleuropneumonia:

(show top 50) (show all 550)
id Title Authors Year
1
Pharmacokinetic/pharmacodynamic integration and modelling of oxytetracycline for the porcine pneumonia pathogens Actinobacillus pleuropneumoniae and Pasteurella multocida. ( 28090673 )
2017
2
Morphological characterization and immunohistochemical detection of the proinflammatory cytokines IL-1I^, IL-17A, and TNF-I+ in lung lesions associated with contagious bovine pleuropneumonia. ( 26837619 )
2016
3
Coinfection by Ureaplasma spp., Photobacterium damselae and an Actinomyces-like microorganism in a bottlenose dolphin (Tursiops truncatus) with pleuropneumonia stranded along the Adriatic coast of Italy. ( 27033917 )
2016
4
Community-acquired pleuropneumonia in children: Bacteriological and therapeutic challenges. ( 27704513 )
2016
5
A meta-analysis of contagious caprine pleuropneumonia (CCPP) in Ethiopia. ( 26943994 )
2016
6
Recombinant Mycoplasma mycoides proteins elicit protective immune responses against contagious bovine pleuropneumonia. ( 26964722 )
2016
7
Qualitative and quantitative impacts assessment of contagious bovine pleuropneumonia in Fulani pastoral herds of North-central Nigeria: The associated socio-cultural factors. ( 27237398 )
2016
8
Complete Genome Sequence of Mycoplasma mycoides subsp. mycoides T1/44, a Vaccine Strain against Contagious Bovine Pleuropneumonia. ( 27081135 )
2016
9
Capsular polysaccharide from Mycoplasma mycoides subsp. mycoides shows potential for protection against contagious bovine pleuropneumonia. ( 27496744 )
2016
10
Contagious bovine pleuropneumonia: Seroprevalence and risk factors in Western Oromia, Ethiopia. ( 27247066 )
2016
11
Development of a Novel Cocktail Enzyme-Linked Immunosorbent Assay and a Field-Applicable Lateral-Flow Rapid Test for Diagnosis of Contagious Bovine Pleuropneumonia. ( 27053669 )
2016
12
Whole-Genome Sequencing of Mycoplasma mycoides subsp. mycoides Italian Strain 57/13, the Causative Agent of Contagious Bovine Pleuropneumonia. ( 25814605 )
2015
13
The Association of Fibrinous Pleural Effusion with Survival and Complications in Horses with Pleuropneumonia (2002-2012): 74 Cases. ( 26259510 )
2015
14
Abattoir surveillance demonstrates contagious bovine pleuropneumonia is widespread in Tanzania. ( 26315150 )
2015
15
Therapeutic effect of Chinese patent medicine "Wuhuanghu" on porcine infectious pleuropneumonia and its acute and subchronic toxicity as well as evaluation of safety pharmacology. ( 26245812 )
2015
16
Streptococcus equi subsp zooepidemicus pleuropneumonia and peritonitis in a dromedary camel (Camelus dromedarius) calf in North America. ( 26176731 )
2015
17
The Use of Recombinant Tissue Plasminogen Activator (rTPA) in The Treatment of Fibrinous Pleuropneumonia in Horses: 25 Cases (2007-2012). ( 26256909 )
2015
18
Seroprevalence of contagious bovine pleuropneumonia (CBPP) in Mali. ( 25433650 )
2015
19
Participatory Epidemiology of Ethnoveterinary Practices Fulani Pastoralists Used to Manage Contagious Bovine Pleuropneumonia and Other Cattle Ailments in Niger State, Nigeria. ( 26464953 )
2015
20
Update on Bacterial Pneumonia and Pleuropneumonia in the Adult Horse. ( 25600453 )
2015
21
Sero-positivity and associated risk factors for contagious bovine pleuropneumonia under two cattle production systems in North Central Nigeria. ( 26563271 )
2015
22
Isolation and Phylogenetic Characterization of Streptococcus halichoeri from a European Badger (Meles meles) with Pyogranulomatous Pleuropneumonia. ( 25678424 )
2015
23
Non-haemolytic Mannheimia haemolytica as a cause of pleuropneumonia and septicemia in a calf. ( 26344042 )
2015
24
Proteomic characterization of pleural effusion, a specific host niche of Mycoplasma mycoides subsp. mycoides from cattle with contagious bovine pleuropneumonia (CBPP). ( 26476145 )
2015
25
Sero-prevalence of Contagious Bovine Pleuropneumonia (CBPP) in bulls originated from Borena pastoral area of Southern Ethiopia. ( 25863957 )
2015
26
Mathematical modelling of the transmission dynamics of contagious bovine pleuropneumonia reveals minimal target profiles for improved vaccines and diagnostic assays. ( 25668725 )
2015
27
A large-scale genomic approach affords unprecedented resolution for the molecular epidemiology and evolutionary history of contagious caprine pleuropneumonia. ( 26149260 )
2015
28
Analysis of immune responses to recombinant proteins from strains of Mycoplasma mycoides subsp. mycoides, the causative agent of contagious bovine pleuropneumonia. ( 26384697 )
2015
29
Serological prevalence of contagious bovine pleuropneumonia in agro-pastoral areas of Nigeria. ( 25894821 )
2015
30
Quantitative risk assessment of entry of contagious bovine pleuropneumonia through live cattle imported from northwestern Ethiopia. ( 26427634 )
2015
31
Comparison of in vivo and in vitro properties of capsulated and noncapsulated variants of Mycoplasma mycoides subsp. mycoides strain AfadAc: a potential new insight into the biology of contagious bovine pleuropneumonia. ( 25123820 )
2014
32
Efficacy of vaccination against Actinobacillus pleuropneumoniae in two Belgian farrow-to-finish pig herds with a history of chronic pleurisy. ( 24552670 )
2014
33
An international collaborative study to determine the prevalence of contagious caprine pleuropneumonia by monoclonal antibody-based cELISA. ( 24565080 )
2014
34
Severe, diffuse fibrinonecrotic pleuropneumonia in a cat affected by multiple viral infection. ( 24817332 )
2014
35
Fatal transmission of contagious caprine pleuropneumonia to an Arabian oryx (Oryx leucoryx). ( 25069622 )
2014
36
Oral immunization against porcine pleuropneumonia using the cubic phase of monoolein and purified toxins of Actinobacillus pleuropneumoniae. ( 25446832 )
2014
37
Estimation of impact of contagious bovine pleuropneumonia on pastoralists in Kenya. ( 24767814 )
2014
38
Willingness to pay for contagious bovine pleuropneumonia vaccination in Narok South District of Kenya. ( 24774477 )
2014
39
High antibody titres against predicted Mycoplasma surface proteins do not prevent sequestration in infected lung tissue in the course of experimental contagious bovine pleuropneumonia. ( 24880898 )
2014
40
Characterization of the in vitro core surface proteome of Mycoplasma mycoides subsp. mycoides, the causative agent of contagious bovine pleuropneumonia. ( 24332827 )
2014
41
Blood values of captive beira antelope (Dorcatragus megalotis) prior to and during an outbreak of fibrinous pleuropneumonia syndrome (FPPS). ( 25632657 )
2014
42
Control of contagious bovine pleuropneumonia: knowledge, attitudes, perceptions and practices in Narok district of Kenya. ( 24768437 )
2014
43
Contagious caprine pleuropneumonia in endangered Tibetan antelope, China, 2012. ( 24274020 )
2013
44
Characterization of anamnestic T-cell responses induced by conventional vaccines against contagious bovine pleuropneumonia. ( 23469008 )
2013
45
Recent observations on site reactions in cattle to vaccination against contagious bovine pleuropneumonia (CBPP) using T1/44 vaccine in Zambia. ( 23728802 )
2013
46
Exploring farmer preferences for contagious bovine pleuropneumonia vaccination: a case study of Narok District of Kenya. ( 23465609 )
2013
47
Development of an improved vaccine for contagious bovine pleuropneumonia: an African perspective on challenges and proposed actions. ( 24359340 )
2013
48
Differences in purinergic amplification of osmotic cell lysis by the pore-forming RTX toxins Bordetella pertussis CyaA and Actinobacillus pleuropneumoniae ApxIA: the role of pore size. ( 24082076 )
2013
49
Private sector involvement in the control of contagious bovine pleuropneumonia (CBPP) in the Kazungula district of Zambia benefitted the community and the control strategy. ( 23334379 )
2013
50
An abattoir survey of contagious bovine pleuropneumonia lesions in slaughtered cattle in selected districts in Northern Tanzania. ( 23620855 )
2013

Variations for Pleuropneumonia

Expression for Pleuropneumonia

Search GEO for disease gene expression data for Pleuropneumonia.

Pathways for Pleuropneumonia

Pathways related to Pleuropneumonia according to GeneCards Suite gene sharing:

(show all 19)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.25 CD40LG CXCL9 IL1R1 IRAK1 IRAK3 IRAK4
2
Show member pathways
13.05 CD79A IL1R1 IRAK1 IRAK3 IRAK4 MYD88
3
Show member pathways
12.75 CXCL9 IRAK1 IRAK3 IRAK4 MYD88
4
Show member pathways
12.55 CD40LG IL1R1 IRAK1 IRAK3 IRAK4 MYD88
5
Show member pathways
12.48 CD40LG IL1R1 IRAK1 IRAK3 IRAK4 MYD88
6
Show member pathways
12.28 IRAK1 IRAK3 IRAK4 MYD88
7 12.23 CD40LG CD79A IRAK1 IRAK3 IRAK4 MYD88
8
Show member pathways
12.14 IL1R1 IRAK1 IRAK3 IRAK4 MYD88
9
Show member pathways
12.1 IRAK1 IRAK3 IRAK4 MYD88
10
Show member pathways
12.06 IL1R1 IRAK1 IRAK3 IRAK4 MYD88
11 12.05 FCGR3A FCGR3B IRAK1 IRAK4 MYD88
12
Show member pathways
11.94 IL1R1 IRAK1 IRAK3 IRAK4 MYD88
13 11.6 IRAK1 IRAK4 MYD88
14 11.56 CD40LG FCGR3A FCGR3B
15 11.38 CD40LG HBB MYD88
16
Show member pathways
11.37 CD40LG FCGR3A FCGR3B IRAK1 IRAK4 MYD88
17 11.33 CD40LG IL1R1 IRAK1 IRAK4 MYD88
18 11.19 IL1R1 IRAK1 IRAK3 MYD88
19 11.07 IL1R1 IRAK1 MYD88

GO Terms for Pleuropneumonia

Cellular components related to Pleuropneumonia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 9.46 CD40LG CD79A CXCL9 FCGR3A
2 extracellular space GO:0005615 9.23 CD40LG CELA3B COL18A1 CXCL9 GGT1 HBB
3 hemoglobin complex GO:0005833 8.96 HBB HBD

Biological processes related to Pleuropneumonia according to GeneCards Suite gene sharing:

(show all 15)
id Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.92 CD40LG CXCL9 FCGR3A FCGR3B IL1R1
2 response to lipopolysaccharide GO:0032496 9.8 CXCL9 IRAK1 IRAK3 MYD88
3 cytokine-mediated signaling pathway GO:0019221 9.72 IL1R1 IRAK1 IRAK3 IRAK4 MYD88
4 regulation of inflammatory response GO:0050727 9.69 GGT1 IL1R1 MYD88
5 positive regulation of smooth muscle cell proliferation GO:0048661 9.65 IRAK1 IRAK4 MYD88
6 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.65 CD40LG IRAK1 IRAK3 IRAK4 MYD88
7 JNK cascade GO:0007254 9.63 IRAK1 IRAK4 MYD88
8 toll-like receptor signaling pathway GO:0002224 9.58 IRAK1 IRAK4 MYD88
9 oxygen transport GO:0015671 9.55 HBB HBD
10 positive regulation of endothelial cell apoptotic process GO:2000353 9.54 CD40LG COL18A1
11 toll-like receptor 9 signaling pathway GO:0034162 9.54 IRAK1 IRAK4 MYD88
12 response to interleukin-1 GO:0070555 9.46 IL1R1 IRAK1 IRAK3 MYD88
13 response to peptidoglycan GO:0032494 9.43 IRAK3 MYD88
14 MyD88-dependent toll-like receptor signaling pathway GO:0002755 9.26 IRAK1 IRAK3 IRAK4 MYD88
15 interleukin-1-mediated signaling pathway GO:0070498 8.92 IL1R1 IRAK1 IRAK3 IRAK4

Molecular functions related to Pleuropneumonia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 interleukin-1 receptor binding GO:0005149 9.16 IRAK4 MYD88
2 oxygen transporter activity GO:0005344 8.96 HBB HBD
3 IgG binding GO:0019864 8.62 FCGR3A FCGR3B

Sources for Pleuropneumonia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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