MCID: PLR005
MIFTS: 43

Pleuropneumonia malady

Respiratory diseases category
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Summaries for Pleuropneumonia

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Sources:
8Disease Ontology, 65Wikipedia, 33MalaCards
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Disease Ontology:8 A pneumonia accompanied by inflammation of the pleura and accumulation of pus in the pleural space caused by bacteria.

MalaCards: Pleuropneumonia, also known as pleurobronchopneumonia, is related to hepatitis and pneumonia. An important gene associated with Pleuropneumonia is PRF1 (perforin 1 (pore forming protein)), and among its related pathways is Glucocorticoid receptor regulatory network. The compounds sodium dodecylsulfate and antipyrine have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and kidney, and related mouse phenotypes are homeostasis/metabolism and growth/size/body.

Wikipedia:65 Contagious bovine pleuropneumonia (CBPP - also known as lung plague), is a contagious bacterial disease... more...

Aliases & Classifications for Pleuropneumonia

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Sources:
8Disease Ontology, 62UMLS, 58SNOMED-CT, 35MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Respiratory diseases


Aliases & Descriptions:

pleuropneumonia 8 62
pleurobronchopneumonia 8


External Ids:

Disease Ontology8 DOID:14319
SNOMED-CT58 60485005
MeSH35 D011001

Related Diseases for Pleuropneumonia

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Pleuropneumonia:



Diseases related to pleuropneumonia

Symptoms for Pleuropneumonia

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Drugs & Therapeutics for Pleuropneumonia

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Sources:
42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Pleuropneumonia

Search NIH Clinical Center for Pleuropneumonia

Genetic Tests for Pleuropneumonia

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Anatomical Context for Pleuropneumonia

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33MalaCards
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MalaCards organs/tissues related to Pleuropneumonia:

33
Lung, Testes, Kidney, Skin, T cells, Lymph node

Animal Models for Pleuropneumonia or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Pleuropneumonia:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053768.1GGT1, TBP, PRF1, TF
2MP:00053787.8TF, PRF1, TBP, GGT1
3MP:00107687.4GGT1, KRT17, TBP, PRF1, TF

Publications for Pleuropneumonia

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Sources:
52PubMed
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Articles related to Pleuropneumonia:

(show top 50)    (show all 503)
idTitleAuthorsYear
1
Recent observations on site reactions in cattle to vaccination against contagious bovine pleuropneumonia (CBPP) using T1/44 vaccine in Zambia. (23728802)
2013
2
Private sector involvement in the control of contagious bovine pleuropneumonia (CBPP) in the Kazungula district of Zambia benefitted the community and the control strategy. (23334379)
2013
3
Performance evaluation of two serological tests for contagious bovine pleuropneumonia (CBPP) detection in an enzootic area using a Bayesian framework. (22528527)
2012
4
What is your diagnosis? Actinobacillus pleuropneumonia. (22812465)
2012
5
Caprine pleuropneumonia in Beetal goats [corrected]. (21735340)
2012
6
A history of the prevalence and control of contagious bovine pleuropneumonia in China. (21439870)
2012
7
Seroprevalence of contagious bovine pleuropneumonia at export quarantine centers in and around Adama, Ethiopia. (22695989)
2012
8
First report on the molecular prevalence of Mycoplasma capricolum subspecies capripneumoniae (Mccp) in goats the cause of contagious caprine pleuropneumonia (CCPP) in Balochistan province of Pakistan. (20091126)
2010
9
Isolation rates, serovars, and toxin genotypes of nicotinamide adenine dinucleotide-independent Actinobacillus pleuropneumoniae among pigs suffering from pleuropneumonia in Spain. (19901289)
2009
10
Multifocal granulomatous hepatitis caused by Actinobacillus pleuropneumoniae serotype 2 in slaughter pigs. (18617183)
2008
11
Analysis of cellular responses to Mycoplasma mycoides subsp. mycoides small colony biotype associated with control of contagious bovine pleuropneumonia. (18073095)
2008
12
A hematogenic pleuropneumonia caused by postoperative septic thrombophlebitis in a Thoroughbred gelding. (15028889)
2004
13
A specific PCR for the identification of Mycoplasma capricolum subsp. capripneumoniae, the causative agent of contagious caprine pleuropneumonia (CCPP). (15530747)
2004
14
Contagious bovine pleuropneumonia (CBPP) caused by vaccine strain T1/44 of Mycoplasma mycoides subsp. mycoides SC. (15036531)
2004
15
Abattoir-based survey of contagious bovine pleuropneumonia in cattle in Turkey. (12638910)
2003
16
Contagious bovine pleuropneumonia and vaccine strain T1/44. (12074243)
2002
17
Effects of pentoxifylline on inflammatory cytokine expression and acute pleuropneumonia in swine. (11999342)
2002
18
Pathological, immunohistochemical and bacteriological findings in kidneys of cattle with contagious bovine pleuropneumonia (CBPP). (11222005)
2001
19
Prevalence of contagious bovine pleuropneumonia (CBPP) in northern Nigeria. (11087957)
2000
20
Characterization of polymorphic mononuclear cell in porcine Actinobacillus pleuropneumonia. (9208480)
1997
21
ISCOM vaccine against contagious bovine pleuropneumonia (CBPP). 1. Biochemical and immunological characterization. (9437824)
1997
22
A pathological and immunohistochemical study of caprine pleuropneumonia induced by subspecies of Mycoplasma mycoides. (8814532)
1996
23
Contagious bovine pleuropneumonia vaccines: the current situation and the need for improvement. (9190019)
1996
24
Acute pleuropneumonia in Barbary sheep (Amnotragus lervia) associated with Chromobacterium violaceum. (8736506)
1996
25
Contagious bovine pleuropneumonia in northern Tanzania, culture confirmation and serological studies. (8966759)
1995
26
Contagious bovine pleuropneumonia in Australia: some historic highlights from entry to eradication. (1492827)
1992
27
Drug resistant plasmid of Actinobacillus pleuropneumoniae isolated from swine pleuropneumonia in Thailand. (1431383)
1992
28
Resurgence of contagious bovine pleuropneumonia in Nigeria. (1472726)
1992
29
Pneumocystis carinii pleuropneumonia after aerosolized pentamidine prophylaxis. (1816116)
1991
30
The microbe of pleuropneumonia. 1896. (2184501)
1990
31
Mycoplasmas isolated from goats and sheep with pleuropneumonia in Saudi Arabia. (4089970)
1985
32
Porcine pleuropneumonia associated with Haemophilus pleuropneumoniae serotype 3 in Quebec. (6523705)
1984
33
Treatment of contagious caprine pleuropneumonia. (6719830)
1984
34
Pleuropneumonia in pigs caused by Haemophilus parahaemolyticus. (4415108)
1974
35
Susceptibility to contagious bovine pleuropneumonia. (4612944)
1974
36
The efficacy of T strain broth vaccine against contagious bovine pleuropneumonia: in-contact trials carried out two years after primary vaccination. (5062155)
1972
37
History of contagious bovine pleuropneumonia in Kenya. (4948533)
1971
38
Contagious bovine pleuropneumonia--a survey using the Huddart plate test and a mobile laboratory. (5812791)
1969
39
Increased sensitivity of the complement fixation test for contagious bovine pleuropneumonia on sera preserved with phenol. (5751958)
1968
40
Study on the virulence of contagious bovine pleuropneumonia organism (Assam strain) on subcutaneous pathogenicity test. (5751813)
1968
41
Contagious bovine pleuropneumonia: Serologic response of cattle after single and double vaccination with T-1 culture vaccine. (4984508)
1968
42
Studies on avian pleuropneumonia-like organisms. IV. Raising PPLO-free flock by antibiotic dip treatment. (6068468)
1967
43
Studies on avian pleuropneumonia-like organisms. II. Transovarian transmission. (6066400)
1967
44
The use of sodium aurothiomalate in the eradication of pleuropneumonia-like organisms (PPLO) from a chronically infected strain of hamster kidney cells (BHK 21 C13). (5964384)
1966
45
AN IN VITRO COMPARISON OF THE EFFECT OF SOME ANTIBACTERIAL, ANTIFUNGAL AND ANTIPROTOZOAL AGENTS ON VARIOUS STRAINS OF MYCOPLASMA (PLEUROPNEUMONIA-LIKE ORGANISMS: P.P.L.O.). (14271924)
1965
46
PORCINE CONTAGIOUS PLEUROPNEUMONIA. 3. INTERRELATIONSHIP OF HEMOPHILUS PLEUROPNEUMONIAE TO OTHER SPECIES OF HEMOPHILUS: NUTRITIONAL, METABOLIC, TRANSFORMATION, AND ELECTRON MICROSCOPY STUDIES. (14194390)
1964
47
Arginine breakdown in mammalian cell culture contaminated with pleuropneumonia-like organisms (PPLO). (13991728)
1963
48
Electrical properties of the membranes of the pleuropneumonia-like organism A 5969. (13909656)
1962
49
Isolation and incidence of pleuropneumonia-like organisms from the human oral cavity. (13912149)
1962
50
The histopathologic characteristics of diseases producing inflammation of the air sacs in turkeys. A comparative study of pleuropneumonia-like organisms and ornithosis in pure and mixed infections. (13688256)
1961

Variations for Pleuropneumonia

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Expression for genes affiliated with Pleuropneumonia

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Pleuropneumonia

Search GEO for disease gene expression data for Pleuropneumonia.

Pathways for genes affiliated with Pleuropneumonia

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50PathCards, 38NCBI BioSystems Database
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Pathways related to Pleuropneumonia according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3KRT17, TBP

Compounds for genes affiliated with Pleuropneumonia

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Sources:
45Novoseek, 11DrugBank, 29IUPHAR, 24HMDB, 51PharmGKB, 3BitterDB, 61Tocris Bioscience
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Compounds related to Pleuropneumonia according to GeneCards/GeneDecks:

(show all 30)
idCompoundScoreTop Affiliating Genes
1sodium dodecylsulfate459.6KRT17, TBP
2antipyrine45 1110.5TF, GGT1
3gentamicin45 1110.5TF, GGT1
4acetaldehyde29 45 2411.5GGT1, TF
5ribavirin45 51 1111.5GGT1, TF
6vitamin b12459.5GGT1, TF
7guanine45 24 1111.4GGT1, TBP
8betacarotene459.4TF, GGT1
9phenobarbital45 29 51 1112.4GGT1, TF
10tbps45 2910.4TBP, TF
11histidine459.4TBP, PRF1
12tocopherol459.4TBP, TF
13hydrocortisone45 3 61 1112.4KRT17, TF
14sialic acid459.4GGT1, TF
15cocaine45 1110.4GGT1, TF
16choline45 24 1111.3TF, GGT1
17tacrolimus45 51 1111.3GGT1, TF
18vitamin a45 24 1111.3GGT1, TF
19agar459.2PRF1, TF
20methotrexate51 45 1111.2TF, GGT1
21n acetylcysteine459.0GGT1, TF
22cholesterol45 29 24 1112.0GGT1, PRF1, TF
23alpha tocopherol458.9GGT1, TBP, TF
24adenine45 24 1110.9TF, TBP, GGT1
25thyroxine45 249.9GGT1, TBP, TF
26glutamine458.9TF, TBP, GGT1
27iron45 249.9GGT1, TBP, TF
28ascorbic acid45 249.8GGT1, TF
29alanine458.8TF, TBP, GGT1
30serine458.7PRF1, TBP, KRT17, GGT1

GO Terms for genes affiliated with Pleuropneumonia

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16Gene Ontology
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Cellular components related to Pleuropneumonia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cytoplasmic membrane-bounded vesicleGO:0160239.2PRF1, TF

Molecular functions related to Pleuropneumonia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:0055157.5GGT1, KRT17, TBP, PRF1, TF

Products for genes affiliated with Pleuropneumonia

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  • Antibodies
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  • Antibodies

Sources for Pleuropneumonia

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet