MCID: PLR005
MIFTS: 36

Pleuropneumonia malady

Summaries for Pleuropneumonia

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Disease Ontology:9 A pneumonia accompanied by inflammation of the pleura and accumulation of pus in the pleural space caused by bacteria.

MalaCards based summary: Pleuropneumonia, also known as pleurobronchopneumonia, is related to hepatitis and pneumonia. An important gene associated with Pleuropneumonia is PRF1 (perforin 1 (pore forming protein)), and among its related pathways is Glucocorticoid receptor regulatory network. The compounds sodium dodecylsulfate and antipyrine have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and kidney, and related mouse phenotypes are homeostasis/metabolism and growth/size/body.

Wikipedia:63 Pleuropneumonia is inflammation of the lungs and pleura, pleurisy being the inflammation of the pleura... more...

Aliases & Classifications for Pleuropneumonia

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Pleuropneumonia, Aliases & Descriptions:

Name: Pleuropneumonia 9 60
 
Pleurobronchopneumonia 9


External Ids:

Disease Ontology9 DOID:14319
SNOMED-CT55 60485005
MeSH33 D011001

Related Diseases for Pleuropneumonia

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Graphical network of the top 20 diseases related to Pleuropneumonia:



Diseases related to pleuropneumonia

Symptoms for Pleuropneumonia

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Drugs & Therapeutics for Pleuropneumonia

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Drug clinical trials:

Search ClinicalTrials for Pleuropneumonia

Search NIH Clinical Center for Pleuropneumonia

Genetic Tests for Pleuropneumonia

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Anatomical Context for Pleuropneumonia

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MalaCards organs/tissues related to Pleuropneumonia:

31
Lung, Testes, Kidney, Skin, T cells, Lymph node

Animal Models for Pleuropneumonia or affiliated genes

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MGI Mouse Phenotypes related to Pleuropneumonia:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053768.1GGT1, TBP, PRF1, TF
2MP:00053787.8TF, PRF1, TBP, GGT1
3MP:00107687.4GGT1, KRT17, TBP, PRF1, TF

Publications for Pleuropneumonia

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Articles related to Pleuropneumonia:

(show top 50)    (show all 518)
idTitleAuthorsYear
1
High antibody titres against predicted Mycoplasma surface proteins do not prevent sequestration in infected lung tissue in the course of experimental contagious bovine pleuropneumonia. (24880898)
2014
2
Recent observations on site reactions in cattle to vaccination against contagious bovine pleuropneumonia (CBPP) using T1/44 vaccine in Zambia. (23728802)
2013
3
Private sector involvement in the control of contagious bovine pleuropneumonia (CBPP) in the Kazungula district of Zambia benefitted the community and the control strategy. (23334379)
2013
4
Performance evaluation of two serological tests for contagious bovine pleuropneumonia (CBPP) detection in an enzootic area using a Bayesian framework. (22528527)
2012
5
What is your diagnosis? Actinobacillus pleuropneumonia. (22812465)
2012
6
Caprine pleuropneumonia in Beetal goats [corrected]. (21735340)
2012
7
A history of the prevalence and control of contagious bovine pleuropneumonia in China. (21439870)
2012
8
Seroprevalence of contagious bovine pleuropneumonia at export quarantine centers in and around Adama, Ethiopia. (22695989)
2012
9
First report on the molecular prevalence of Mycoplasma capricolum subspecies capripneumoniae (Mccp) in goats the cause of contagious caprine pleuropneumonia (CCPP) in Balochistan province of Pakistan. (20091126)
2010
10
Isolation rates, serovars, and toxin genotypes of nicotinamide adenine dinucleotide-independent Actinobacillus pleuropneumoniae among pigs suffering from pleuropneumonia in Spain. (19901289)
2009
11
Multifocal granulomatous hepatitis caused by Actinobacillus pleuropneumoniae serotype 2 in slaughter pigs. (18617183)
2008
12
A hematogenic pleuropneumonia caused by postoperative septic thrombophlebitis in a Thoroughbred gelding. (15028889)
2004
13
A specific PCR for the identification of Mycoplasma capricolum subsp. capripneumoniae, the causative agent of contagious caprine pleuropneumonia (CCPP). (15530747)
2004
14
Contagious bovine pleuropneumonia (CBPP) caused by vaccine strain T1/44 of Mycoplasma mycoides subsp. mycoides SC. (15036531)
2004
15
Abattoir-based survey of contagious bovine pleuropneumonia in cattle in Turkey. (12638910)
2003
16
Contagious bovine pleuropneumonia and vaccine strain T1/44. (12074243)
2002
17
Effects of pentoxifylline on inflammatory cytokine expression and acute pleuropneumonia in swine. (11999342)
2002
18
Pathological, immunohistochemical and bacteriological findings in kidneys of cattle with contagious bovine pleuropneumonia (CBPP). (11222005)
2001
19
Characterization of polymorphic mononuclear cell in porcine Actinobacillus pleuropneumonia. (9208480)
1997
20
ISCOM vaccine against contagious bovine pleuropneumonia (CBPP). 1. Biochemical and immunological characterization. (9437824)
1997
21
A pathological and immunohistochemical study of caprine pleuropneumonia induced by subspecies of Mycoplasma mycoides. (8814532)
1996
22
Contagious bovine pleuropneumonia vaccines: the current situation and the need for improvement. (9190019)
1996
23
Acute pleuropneumonia in Barbary sheep (Amnotragus lervia) associated with Chromobacterium violaceum. (8736506)
1996
24
Contagious bovine pleuropneumonia in northern Tanzania, culture confirmation and serological studies. (8966759)
1995
25
Contagious bovine pleuropneumonia in Australia: some historic highlights from entry to eradication. (1492827)
1992
26
Drug resistant plasmid of Actinobacillus pleuropneumoniae isolated from swine pleuropneumonia in Thailand. (1431383)
1992
27
Resurgence of contagious bovine pleuropneumonia in Nigeria. (1472726)
1992
28
Pneumocystis carinii pleuropneumonia after aerosolized pentamidine prophylaxis. (1816116)
1991
29
The microbe of pleuropneumonia. 1896. (2184501)
1990
30
Mycoplasmas isolated from goats and sheep with pleuropneumonia in Saudi Arabia. (4089970)
1985
31
Porcine pleuropneumonia associated with Haemophilus pleuropneumoniae serotype 3 in Quebec. (6523705)
1984
32
Treatment of contagious caprine pleuropneumonia. (6719830)
1984
33
Treatment of contagious caprine pleuropneumonia. (6170140)
1981
34
Pleuropneumonia in pigs caused by Haemophilus parahaemolyticus. (4415108)
1974
35
Susceptibility to contagious bovine pleuropneumonia. (4612944)
1974
36
The efficacy of T strain broth vaccine against contagious bovine pleuropneumonia: in-contact trials carried out two years after primary vaccination. (5062155)
1972
37
History of contagious bovine pleuropneumonia in Kenya. (4948533)
1971
38
Contagious bovine pleuropneumonia--a survey using the Huddart plate test and a mobile laboratory. (5812791)
1969
39
Increased sensitivity of the complement fixation test for contagious bovine pleuropneumonia on sera preserved with phenol. (5751958)
1968
40
Study on the virulence of contagious bovine pleuropneumonia organism (Assam strain) on subcutaneous pathogenicity test. (5751813)
1968
41
Contagious bovine pleuropneumonia: Serologic response of cattle after single and double vaccination with T-1 culture vaccine. (4984508)
1968
42
Studies on avian pleuropneumonia-like organisms. IV. Raising PPLO-free flock by antibiotic dip treatment. (6068468)
1967
43
Studies on avian pleuropneumonia-like organisms. II. Transovarian transmission. (6066400)
1967
44
The use of sodium aurothiomalate in the eradication of pleuropneumonia-like organisms (PPLO) from a chronically infected strain of hamster kidney cells (BHK 21 C13). (5964384)
1966
45
AN IN VITRO COMPARISON OF THE EFFECT OF SOME ANTIBACTERIAL, ANTIFUNGAL AND ANTIPROTOZOAL AGENTS ON VARIOUS STRAINS OF MYCOPLASMA (PLEUROPNEUMONIA-LIKE ORGANISMS: P.P.L.O.). (14271924)
1965
46
PORCINE CONTAGIOUS PLEUROPNEUMONIA. 3. INTERRELATIONSHIP OF HEMOPHILUS PLEUROPNEUMONIAE TO OTHER SPECIES OF HEMOPHILUS: NUTRITIONAL, METABOLIC, TRANSFORMATION, AND ELECTRON MICROSCOPY STUDIES. (14194390)
1964
47
Arginine breakdown in mammalian cell culture contaminated with pleuropneumonia-like organisms (PPLO). (13991728)
1963
48
Electrical properties of the membranes of the pleuropneumonia-like organism A 5969. (13909656)
1962
49
Isolation and incidence of pleuropneumonia-like organisms from the human oral cavity. (13912149)
1962
50
The histopathologic characteristics of diseases producing inflammation of the air sacs in turkeys. A comparative study of pleuropneumonia-like organisms and ornithosis in pure and mixed infections. (13688256)
1961

Variations for Pleuropneumonia

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Expression for genes affiliated with Pleuropneumonia

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Search GEO for disease gene expression data for Pleuropneumonia.

Pathways for genes affiliated with Pleuropneumonia

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Pathways related to Pleuropneumonia according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3KRT17, TBP

Compounds for genes affiliated with Pleuropneumonia

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Compounds related to Pleuropneumonia according to GeneCards Suite gene sharing:

(show all 30)
idCompoundScoreTop Affiliating Genes
1sodium dodecylsulfate439.6KRT17, TBP
2antipyrine43 1210.5TF, GGT1
3gentamicin43 1210.5TF, GGT1
4acetaldehyde28 43 2411.5GGT1, TF
5ribavirin43 49 1211.5GGT1, TF
6vitamin b12439.5GGT1, TF
7guanine43 24 1211.4GGT1, TBP
8betacarotene439.4TF, GGT1
9phenobarbital43 28 49 1212.4GGT1, TF
10tbps43 2810.4TBP, TF
11histidine439.4TBP, PRF1
12tocopherol439.4TBP, TF
13hydrocortisone43 2 59 1212.4KRT17, TF
14sialic acid439.4GGT1, TF
15cocaine43 1210.4GGT1, TF
16choline43 24 1211.3TF, GGT1
17tacrolimus43 49 1211.3GGT1, TF
18vitamin a43 24 1211.3GGT1, TF
19agar439.2PRF1, TF
20methotrexate49 43 1211.2TF, GGT1
21n acetylcysteine439.0GGT1, TF
22cholesterol43 28 24 1212.0GGT1, PRF1, TF
23alpha tocopherol438.9GGT1, TBP, TF
24adenine43 24 1210.9TF, TBP, GGT1
25thyroxine43 249.9GGT1, TBP, TF
26glutamine438.9TF, TBP, GGT1
27iron43 249.9GGT1, TBP, TF
28ascorbic acid43 249.8GGT1, TF
29alanine438.8TF, TBP, GGT1
30serine438.7PRF1, TBP, KRT17, GGT1

GO Terms for genes affiliated with Pleuropneumonia

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Cellular components related to Pleuropneumonia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytoplasmic membrane-bounded vesicleGO:00160239.2PRF1, TF

Molecular functions related to Pleuropneumonia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:00055157.5GGT1, KRT17, TBP, PRF1, TF

Products for genes affiliated with Pleuropneumonia

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  • Antibodies
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Sources for Pleuropneumonia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet