MCID: PLX002
MIFTS: 39

Plexiform Neurofibroma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Plexiform Neurofibroma

MalaCards integrated aliases for Plexiform Neurofibroma:

Name: Plexiform Neurofibroma 12 29 14 69
Neurofibroma, Plexiform 42
Neurofibroma Plexiform 52

Classifications:



External Ids:

Disease Ontology 12 DOID:5151
MeSH 42 D018318
NCIt 47 C3797
SNOMED-CT 64 403818001 41252002
UMLS 69 C0206728

Summaries for Plexiform Neurofibroma

MalaCards based summary : Plexiform Neurofibroma, also known as neurofibroma, plexiform, is related to neurofibromatosis, type 1 and neurofibroma. An important gene associated with Plexiform Neurofibroma is NF1 (Neurofibromin 1), and among its related pathways/superpathways is Cell cycle_Role of APC in cell cycle regulation. The drugs Peginterferon alfa-2b and Everolimus have been mentioned in the context of this disorder. Affiliated tissues include salivary gland, bone and tongue, and related phenotype is respiratory system.

Related Diseases for Plexiform Neurofibroma

Diseases related to Plexiform Neurofibroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 77)
id Related Disease Score Top Affiliating Genes
1 neurofibromatosis, type 1 11.5
2 neurofibroma 11.0
3 neurofibromatosis-noonan syndrome 10.5 NF1 NF2
4 pediatric fibrosarcoma 10.4 NF1 NF2
5 demyelinating disease 10.4 NF1 NF2
6 benign pleural mesothelioma 10.4 NF1 NF2
7 ovarian disease 10.4 NF1 NF2
8 lung lymphoma 10.4 NF1 NF2
9 epilepsy, familial focal, with variable foci 1 10.4 NF1 NF2
10 diphtheria 10.4 NF1 NF2
11 epidural abscess 10.4 NF1 NF2
12 c-p angle neurinoma 10.4 NF1 NF2
13 vestibular disease 10.4 NF1 NF2
14 peritoneal benign neoplasm 10.3 NF1 NF2
15 clear cell ependymoma 10.3 NF1 NF2
16 surfactant metabolism dysfunction, pulmonary, 5 10.3 NF1 NF2
17 vestibular gland benign neoplasm 10.3 NF1 NF2
18 hypoglossal nerve neoplasm 10.3 NF1 NF2
19 malignant peripheral nerve sheath tumor 10.2
20 postmenopausal atrophic vaginitis 10.2 NF1 NF2
21 lymphoplasmacytic lymphoma 10.1 NF1 NF2
22 hepatitis 10.1
23 connective tissue cancer 10.1 ANK3 NF2
24 small cell sarcoma 10.1 NF1 NF2
25 cervicitis 10.1
26 autosomal dominant deafness-onychodystrophy syndrome 10.0 NF1 SPRED1
27 kidney hypertrophy 10.0 NEK2 NF1 NF2
28 y-linked disease 10.0 NF1 NF2
29 interstitial nephritis, karyomegalic 10.0 NF1 SPRED1
30 choroiditis 9.9
31 laryngitis 9.9
32 ganglioneuroma 9.9
33 glioma 9.9
34 skin epithelioid hemangioma 9.8 NF1 SPRED1
35 bladder urachal squamous cell carcinoma 9.8 NF1 NF2
36 gastrointestinal stromal tumor 9.8
37 otitis media 9.8
38 neurofibromatosis, type 2 9.8
39 myasthenia gravis 9.8
40 sacrococcygeal teratoma 9.8
41 angiosarcoma 9.8
42 oculocutaneous albinism 9.8
43 scoliosis 9.8
44 ptosis 9.8
45 amblyopia 9.8
46 portal hypertension 9.8
47 meningocele 9.8
48 arteriovenous malformation 9.8
49 myopia 9.8
50 leiomyoma 9.8

Graphical network of the top 20 diseases related to Plexiform Neurofibroma:



Diseases related to Plexiform Neurofibroma

Symptoms & Phenotypes for Plexiform Neurofibroma

MGI Mouse Phenotypes related to Plexiform Neurofibroma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 respiratory system MP:0005388 9.02 ANK3 BUB1B NF1 NF2 SPRED1

Drugs & Therapeutics for Plexiform Neurofibroma

Drugs for Plexiform Neurofibroma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 58)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Peginterferon alfa-2b Approved Phase 2,Phase 1 99210-65-8, 215647-85-1
2
Everolimus Approved Phase 2 159351-69-6 6442177
3
Miconazole Approved, Investigational, Vet_approved Phase 2 22916-47-8 4189
4
Sirolimus Approved, Investigational Phase 2 53123-88-9 5284616 6436030 46835353
5
Methotrexate Approved Phase 2 1959-05-2, 59-05-2 126941
6
Vinblastine Approved Phase 2 865-21-4 13342 241903
7
Celecoxib Approved, Investigational Phase 2 169590-42-5 2662
8
Temozolomide Approved, Investigational Phase 2 85622-93-1 5394
9
Vincristine Approved, Investigational Phase 2 2068-78-2, 57-22-7 5978
10
Sunitinib Approved, Investigational Phase 2 341031-54-7, 557795-19-4 5329102
11
Folic Acid Approved, Nutraceutical, Vet_approved Phase 2 59-30-3 6037
12
leucovorin Approved, Nutraceutical Phase 2 58-05-9 143 6006
13
Pirfenidone Investigational Phase 2,Phase 1 53179-13-8 40632
14
tipifarnib Investigational Phase 2 192185-72-1 159324
15
Cediranib Investigational Phase 2 288383-20-0 9933475
16
Maleic acid Experimental Phase 2 110-16-7 444266
17 Anti-Infective Agents Phase 2,Phase 1
18 Antiviral Agents Phase 2,Phase 1
19 Interferon-alpha Phase 2,Phase 1
20 interferons Phase 2,Phase 1
21 Anti-Bacterial Agents Phase 2
22 Antibiotics, Antitubercular Phase 2
23 Antifungal Agents Phase 2
24 Immunosuppressive Agents Phase 2
25 Antimetabolites Phase 2
26 Antimetabolites, Antineoplastic Phase 2
27 Antimitotic Agents Phase 2
28 Antineoplastic Agents, Phytogenic Phase 2
29 Antirheumatic Agents Phase 2,Phase 1
30 Dermatologic Agents Phase 2,Phase 1
31 Folic Acid Antagonists Phase 2
32 Nucleic Acid Synthesis Inhibitors Phase 2
33 Vitamin B Complex Phase 2
34 Pharmaceutical Solutions Phase 2,Phase 1
35 Analgesics Phase 2,Phase 1
36 Analgesics, Non-Narcotic Phase 2,Phase 1
37 Anti-Inflammatory Agents Phase 2,Phase 1
38 Anti-Inflammatory Agents, Non-Steroidal Phase 2,Phase 1
39 Peripheral Nervous System Agents Phase 2,Phase 1
40 Imatinib Mesylate Phase 2,Phase 1 123596
41 Protein Kinase Inhibitors Phase 2,Phase 1
42 Angiogenesis Inhibitors Phase 2,Phase 1
43 Mitogens Phase 1, Phase 2
44 Alkylating Agents Phase 2
45 Cyclooxygenase 2 Inhibitors Phase 2
46 Cyclooxygenase Inhibitors Phase 2
47 Angiogenesis Modulating Agents Phase 2
48 Folate Nutraceutical Phase 2
49 Vitamin B9 Nutraceutical Phase 2
50 tyrosine Nutraceutical Phase 2,Phase 1

Interventional clinical trials:

(show all 40)

id Name Status NCT ID Phase Drugs
1 Acceptance and Commitment Training for Adolescents and Young Adults With Neurofibromatosis Type 1, Plexiform Neurofibromas, and Chronic Pain Recruiting NCT02471339 Phase 3
2 Study of PEG-Intron for Plexiform Neurofibromas Completed NCT00396019 Phase 2 PEG-Intron
3 Use of RAD001 as Monotherapy in the Treatment of Neurofibromatosis 1 Related Internal Plexiform Neurofibromas Completed NCT01412892 Phase 2 RAD001: Everolimus
4 Combination Chemotherapy in Treating Patients With Neurofibromatosis and Progressive Plexiform Neurofibromas Completed NCT00030264 Phase 2 Methotrexate;Vinblastine
5 A Phase II Study of the mTOR Inhibitor Sirolimus in Neurofibromatosis Type 1 Related Plexiform Neurofibromas Completed NCT00634270 Phase 2 Sirolimus
6 Pirfenidone in Children and Young Adults With Neurofibromatosis Type I and Progressive Plexiform Neurofibromas Completed NCT00076102 Phase 2 Pirfenidone
7 R115777 to Treat Children With Neurofibromatosis Type 1 and Progressive Plexiform Neurofibromas Completed NCT00021541 Phase 2 tipifarnib
8 Phase II Study of Gleevec/Imatinib Mesylate (STI-571, NCS 716051) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas Completed NCT01673009 Phase 2 Gleevec
9 Pilot Study of Gleevec/Imatinib Mesylate (STI-571, NSC 716051) in Neurofibromatosis (NF1) Patient With Plexiform Neurofibromas Completed NCT01140360 Phase 1, Phase 2 Gleevec
10 Clinical Trial of Pirfenidone in Adult Patients With Neurofibromatosis 1 Completed NCT00754780 Phase 2 Pirfenidone
11 Study of Imatinib Mesylate in Neurofibromatosis Type I Patients Aged 2 to 21 With Plexiform Neurofibromas Recruiting NCT02177825 Phase 2 Imatinib Mesylate
12 Selumetinib in Treating Patients With Neurofibromatosis Type 1 and Plexiform Neurofibromas That Cannot Be Removed by Surgery Recruiting NCT02407405 Phase 2 Selumetinib
13 PLX3397 in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) Recruiting NCT02390752 Phase 1, Phase 2 PLX3397
14 AZD6244 Hydrogen Sulfate for Children With Nervous System Tumors Recruiting NCT01362803 Phase 1, Phase 2 AZD6244
15 Mitogen Activated Protein Kinase Kinase (MEK1/2) Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in People With Neurofibromatosis Type 1 (NF1) Mutated Gastrointestinal Stromal Tumors (GIST) Recruiting NCT03109301 Phase 2 Selumetinib (AZD6244 hyd sulfate)
16 Cabozantinib for Plexiform Neurofibromas (PN) in Subjects With NF1 (16 Years +) Active, not recruiting NCT02101736 Phase 2 Cabozantinib
17 MEK Inhibitor PD-0325901 Trial in Adolescents and Adults With NF1 Active, not recruiting NCT02096471 Phase 2 PD-0325901
18 Medical Treatment of "High-Risk" Neurofibromas Active, not recruiting NCT00846430 Phase 2 Peg-Interferon alpha-2b;Celecoxib (Celebrex);Temozolomide (temodar);Vincristine Sulfate (Oncovin)
19 Phase II Study of Binimetinib in Children and Adults With NF1 Plexiform Neurofibromas Not yet recruiting NCT03231306 Phase 2 Binimetinib
20 Study of Sutent®/Sunitinib (SU11248) in Subjects With NF-1 Plexiform Neurofibromas Suspended NCT01402817 Phase 2 Sutent®/Sunitinib
21 Efficacy and Safety of RAD001 in Treating Plexiform Neurofibromas (PN) Associated With Neurofibromatosis (NF1) Terminated NCT01365468 Phase 2 Everolimus (RAD001)
22 AZD2171 in Treating Patients With Neurofibromatosis Type 1 and Plexiform Neurofibroma and/or Neurofibroma Near the Spine Terminated NCT00326872 Phase 2 Cediranib Maleate
23 Sorafenib to Treat Children and Young Adults With Neurofibromatosis Type 1 and Inoperable Plexiform Neurofibromas Completed NCT00727233 Phase 1 Nexavar (BAY 43-9006) (Sorafenib);Toxicity, Pharmacokinetics;Pharmacodynamics;Radiographic Evaluation;QOL assessment, Neuropsychological;Bony Toxicity
24 Pirfenidone in Treating Young Patients With Neurofibromatosis Type 1 and Plexiform Neurofibromas Completed NCT00053937 Phase 1 pirfenidone
25 PEG-Interferon Alfa-2b in Treating Young Patients With Plexiform Neurofibroma Completed NCT00253474 Phase 1
26 Study to Investigate Safety, Pharmacokinetic (PK), Pharmacodynamic (PD) and Clinical Activity of Trametinib in Subjects With Cancer or Plexiform Neurofibromas and Trametinib in Combination With Dabrafenib in Subjects With Cancers Harboring V600 Mutations Recruiting NCT02124772 Phase 1 Trametinib;Dabrafenib
27 Phase I Clinical Study of the Safety of Photodynamic Therapy (PDT) Using LS11 in Children With Plexiform Neurofibromas Terminated NCT00716469 Phase 1 LS11
28 Whole Body Magnetic Resonance Imaging With Diffusion Weighted Imaging : Potential Role in Neurofibromatosis Unknown status NCT01777451
29 Analysis of Peripheral Nerve Sheath Tumors (PNSTs) in Neurofibromatosis Type 1 (NF1) Patients Unknown status NCT01218139
30 Study of Plexiform Neurofibromas in Neurofibromatosis Type 1 Completed NCT00006435
31 Study of Tasigna®/Nilotinib (AMN107) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas Completed NCT01275586 Early Phase 1 Tasigna
32 Childhood Cancer and Plexiform Neurofibroma Tissue Microarray for Molecular Target Screening and Clinical Drug Development Completed NCT00340522
33 Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals With Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (PNs) Recruiting NCT02544022
34 Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1 Recruiting NCT02211768 Early Phase 1
35 Natural History Study of Patients With Neurofibromatosis Type I Recruiting NCT00924196
36 Targeting the Mechanisms Underlying Cutaneous Neurofibroma Formation in NF1: A Clinical Translational Approach. Recruiting NCT02777775
37 Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors Recruiting NCT03141021
38 PET/MRI in CNS and Extra-CNS Tumors of Patients With Neurofibromatosis-1 (NF1) Active, not recruiting NCT01800032
39 An Intermediate Access Protocol for Selumetinib for Treatment of Neurofibromatosis Type 1 Available NCT03259633 Selumetinib
40 Fludeoxyglucose F 18 Positron Emission Tomography and Magnetic Resonance Perfusion Imaging in Patients With Neurofibromatosis 1 and Plexiform Neurofibroma Terminated NCT00060008

Search NIH Clinical Center for Plexiform Neurofibroma

Cochrane evidence based reviews: neurofibroma, plexiform

Genetic Tests for Plexiform Neurofibroma

Genetic tests related to Plexiform Neurofibroma:

id Genetic test Affiliating Genes
1 Plexiform Neurofibroma 29

Anatomical Context for Plexiform Neurofibroma

MalaCards organs/tissues related to Plexiform Neurofibroma:

39
Salivary Gland, Bone, Tongue, Skin, Liver, Dorsal Root Ganglion, Trigeminal Ganglion

Publications for Plexiform Neurofibroma

Articles related to Plexiform Neurofibroma:

(show top 50) (show all 308)
id Title Authors Year
1
Monitoring of plexiform neurofibroma in children and adolescents with neurofibromatosis type 1 by [(18) F]FDG-PET imaging. Is it of value in asymptomatic patients? ( 28771999 )
2017
2
Solitary Plexiform Neurofibroma of the Hepatic Artery. ( 28948502 )
2017
3
The primacy of NF1 loss as the driver of tumorigenesis in neurofibromatosis type 1-associated plexiform neurofibromas. ( 28068329 )
2017
4
Giant scalp plexiform neurofibroma associated with NF-1. ( 28928977 )
2017
5
Arteriovenous Malformation Underlying a Plexiform Neurofibroma: An Unusual Presentation. ( 28405554 )
2017
6
Rare triad of periampullary carcinoid, duodenal gastrointestinal stromal tumor and plexiform neurofibroma at hepatic hilum in neurofibromatosis type 1: a case report. ( 28851321 )
2017
7
Plexiform Neurofibroma Overlying Giant CafAc-au-lait Macule. ( 28405569 )
2017
8
An unexpected manifestation of extensive plexiform neurofibroma. ( 28681789 )
2017
9
Plexiform Neurofibroma Involving the Lacrimal Gland. ( 28203199 )
2017
10
Successful treatment by negative-pressure wound therapy for ulcer located on diffuse plexiform neurofibroma. ( 28734012 )
2017
11
An Exceptional Case of Intraparotid Plexiform Neurofibroma Originating from Autonomic Fibers of the Auriculotemporal Nerve. ( 28634493 )
2017
12
Multiple Plexiform Neurofibroma of the Hand Misdiagnosed as Ganglion Cyst. ( 28442864 )
2017
13
Plexiform neurofibroma as a cause of carpal tunnel syndrome in a radial deficiency patient. ( 28554231 )
2017
14
Plexiform neurofibroma causing an ossifying subperiosteal haematoma: a rare case in the tibia of an 11-year-old girl. ( 28623408 )
2017
15
Initial Exploration on Temporal Branch of Facial Nerve Function Preservation in Plexiform Neurofibroma Resection. ( 27526236 )
2016
16
Isolated plexiform neurofibroma mimicking a vascular lesion. ( 27192529 )
2016
17
Plexiform neurofibroma. ( 27824540 )
2016
18
Misdiagnosis of plexiform neurofibroma as venous malformation in pediatric patients. ( 26868134 )
2016
19
Activity of Selumetinib in Neurofibromatosis Type 1-Related Plexiform Neurofibromas. ( 28029918 )
2016
20
The Role of [(18)F]FDG-PET/CT in Predicting Malignant Transformation of Plexiform Neurofibromas in Neurofibromatosis-1. ( 28058117 )
2016
21
Magnetic resonance neurographic confirmation of extensive Plexiform neurofibroma in neurofibromatosis-1 presenting as ambiguous genitalia. ( 27857458 )
2016
22
Plexiform Neurofibroma: A Case Report. ( 26871793 )
2016
23
Sphenoid wing dysplasia and plexiform neurofibroma in neurofibromatosis type 1. ( 27061833 )
2016
24
A case of portal hypertension by presumed as plexiform neurofibroma at the hepatic hilum. ( 27209645 )
2016
25
Solitary Non Syndromic Oral Plexiform Neurofibroma: a Case Report and Review of Literature. ( 27840843 )
2016
26
Genetic basis of a solitary familial plexiform neurofibroma without verified associated neurofibromatosis. ( 27119482 )
2016
27
Dual mTORC1/2 inhibition induces anti-proliferative effect in NF1-associated plexiform neurofibroma and malignant peripheral nerve sheath tumor cells. ( 26840085 )
2016
28
Multifactorial pathological hip subluxation in neurofibromatosis type-1 (NF1) due to intra-articular plexiform neurofibroma, lumbar radiculopathy and neurofibromatous polyneuropathy. ( 27932436 )
2016
29
Improvement of hyperpigmentation within a plexiform neurofibroma after treatment with Q-switched neodymium:yttrium-aluminium-garnet laser. ( 26880255 )
2016
30
Congenital extra calvarial plexiform neurofibroma in occipito-cervical region with Occipital bone defect with neurofibromatosis type 1 and segmental neurofibromatosis: Case report and review of literature. ( 28217149 )
2016
31
Unusual location of a plexiform neurofibroma in the fallopian tube: A case report. ( 27641440 )
2016
32
Multivacuolated mucin-filled cells: a unique cell characteristic of plexiform neurofibroma. A report of 11 cases. ( 27816720 )
2016
33
Hybrid resection of a giant thigh plexiform neurofibroma. ( 25603483 )
2015
34
Ipsilateral Sphenoid Wing Dysplasia, Orbital Plexiform Neurofibroma and Fronto-Parietal Dermal Cylindroma in a Patient with Segmental Neurofibromatosis. ( 26637901 )
2015
35
Preclinical assessment of the anticancer drug response of plexiform neurofibroma tissue using primary cultures. ( 25851896 )
2015
36
Oral manifestations of neurofibromatosis type 1 in children with facial plexiform neurofibroma: report of three cases. ( 25823487 )
2015
37
Infant With a Unilateral Parotid Mass, Recurrent Otitis Media, and Macrocephaly. Plexiform neurofibroma. ( 26237456 )
2015
38
Isolated plexiform neurofibroma of arm with unusual presentation - a rare case report. ( 25738048 )
2015
39
Giant cell tumor of the tendon sheath mimicking a plexiform neurofibroma. ( 26009718 )
2015
40
SRU Cases of the Day: Plexiform Neurofibroma. ( 26561219 )
2015
41
Massive Plexiform Neurofibroma of the Neck and Larynx. ( 26491483 )
2015
42
Partially Plexiform Neurofibroma of the Labia Minora and Clitoral Hood-A Prognostic Dilemma. ( 25658713 )
2015
43
Management of an expansile orbital mass: Plexiform neurofibroma decompression by orbitozygomatic approach. ( 25960281 )
2015
44
Co-occurrence of choroidal pigmented ganglioneuroma and plexiform neurofibroma in a patient with neurofibromatosis 1. ( 24656164 )
2014
45
Extensive Plexiform Neurofibroma in a Premature Neonate. ( 25380612 )
2014
46
Sirolimus for progressive neurofibromatosis type 1-associated plexiform neurofibromas: a Neurofibromatosis Clinical Trials Consortium phase II study. ( 25314964 )
2014
47
Plexiform neurofibroma treated with pharmacopuncture. ( 25780713 )
2014
48
Choroidal Ganglioneuroma and Orbital Plexiform Neurofibroma Presenting as Buphthalmos in an Infant With Neurofibromatosis Type 1. ( 25186217 )
2014
49
Cells of origin in the embryonic nerve roots for NF1-associated plexiform neurofibroma. ( 25446898 )
2014
50
An unusual combination of unilateral orbital plexiform neurofibroma in a patient with oculocutaneous albinism. ( 25005209 )
2014

Variations for Plexiform Neurofibroma

Copy number variations for Plexiform Neurofibroma from CNVD:

7
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1 109397 17 25800000 31800000 Deletion NF1 Plexiform neurofibroma
2 109445 17 26082 26121 Microdeletion SUZ12 Plexiform neurofibroma
3 109456 17 26183 26246 Microdeletion ATAD5 Plexiform neurofibroma
4 109470 17 26273 26310 Microdeletion CENTA2 Plexiform neurofibroma
5 109475 17 26322 26351 Microdeletion RNF135 Plexiform neurofibroma
6 109535 17 26645 26648 Microdeletion OMG Plexiform neurofibroma
7 109543 17 26668 26672 Microdeletion EVI2A Plexiform neurofibroma
8 109598 17 27203 27210 Microdeletion C17orf79 Plexiform neurofibroma

Expression for Plexiform Neurofibroma

Search GEO for disease gene expression data for Plexiform Neurofibroma.

Pathways for Plexiform Neurofibroma

Pathways related to Plexiform Neurofibroma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.36 BUB1B NEK2

GO Terms for Plexiform Neurofibroma

Cellular components related to Plexiform Neurofibroma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytoskeleton GO:0005856 9.26 ANK3 BUB1B NEK2 NF2
2 nucleolus GO:0005730 8.92 KDM2B NEK2 NF1 NF2

Biological processes related to Plexiform Neurofibroma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 negative regulation of cell-matrix adhesion GO:0001953 8.96 NF1 NF2
2 negative regulation of MAPK cascade GO:0043409 8.62 NF1 NF2

Molecular functions related to Plexiform Neurofibroma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytoskeletal protein binding GO:0008092 8.62 ANK3 NF2

Sources for Plexiform Neurofibroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....