MCID: PLM011
MIFTS: 35

Plummer's Disease malady

Category: Endocrine diseases

Aliases & Classifications for Plummer's Disease

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Aliases & Descriptions for Plummer's Disease:

Name: Plummer's Disease 11 13
Toxic Nodular Goiter 11 68
Toxic Nodular Goiter Unspecified 11
 
Toxic Nodular Goiter Nos 11
Goiter Toxic Nodular 50
Plummer Disease 11

Classifications:



External Ids:

Disease Ontology11 DOID:11277
ICD1030 E05.2
ICD9CM32 242.3
NCIt45 C35171

Summaries for Plummer's Disease

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MalaCards based summary: Plummer's Disease, also known as toxic nodular goiter, is related to nodular goiter and goiter. An important gene associated with Plummer's Disease is TG (Thyroglobulin), and among its related pathways are Thyroxine (Thyroid Hormone) Production and Thromboxane A2 receptor signaling. Affiliated tissues include thyroid, and related mouse phenotypes are endocrine/exocrine gland and growth/size/body region.

Related Diseases for Plummer's Disease

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Diseases related to Plummer's Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 72)
idRelated DiseaseScoreTop Affiliating Genes
1nodular goiter11.5
2goiter10.6
3graves' disease10.3
4thyroiditis10.3
5fibrous meningioma10.2TG, TPO
6neuhauser daly magnelli syndrome10.2TG, TPO
7premature closure of the arterial duct10.2TG, TPO
8background diabetic retinopathy10.2TG, TPO
9krabbe disease10.2TG, TPO
10frontal sinusitis10.2TG, TPO
11conjunctival deposit10.2TG, TPO
12caudal regression syndrome10.2TG, TPO
13color blindness10.2TG, TPO
14broad ligament malignant neoplasm10.2TG, TPO
15dysautonomia, familial10.2TG, TPO
16exanthema subitum10.2TG, TPO
17denys-drash syndrome10.2TG, TPO
18chromophobe adenoma10.1ICAM1, SELL
19janus kinase-3 deficiency10.1TG, TPO
20hyperthyroidism10.1
21chromoblastomycosis10.1ICAM1, SELL
22dihydrolipoamide dehydrogenase deficiency10.1TG, TPO
23tonsil cancer10.1ICAM1, SELE
24hypopyon ulcer10.1ICAM1, SELE
25perrault syndrome10.1ICAM1, SELL
26macrodactyly of the foot10.1ICAM1, SELE
27xerophthalmia10.1ICAM1, SELL
28periosteal chondrosarcoma10.1ICAM1, SELE
29sparganosis10.1ICAM1, SELE
30peritoneal serous papillary adenocarcinoma10.1TG, TPO
31right ventricle hypoplasia10.1ICAM1, SELE
32hypotrichosis-lymphedema-telangiectasia-renal defect syndrome10.1SELE, SELL
33prostate disease10.1ICAM1, SELE
34lymph node disease10.1ICAM1, SELE
35strawberry gallbladder10.1ICAM1, SELL
36de quervain disease10.1SELE, SELL
37dermatomycosis10.1ICAM1, SELE
38commensal bacterial infectious disease10.1TG, TPO
39nodular prostate10.1ICAM1, TG, TPO
40hypogonadism cardiomyopathy10.1SHBG, TG
41erb-duchenne and dejerine-klumpke palsies10.1ICAM1, SELE
42diabetes mellitus, insulin-dependent, 1210.0ICAM1, TG, TPO
43powassan encephalitis10.0ICAM1, SELE
44hypothyroidism, congenital, nongoitrous, 110.0TG, THRB, TPO
45dracunculiasis10.0ICAM1, SELE
46autoimmune hemolytic anemia10.0TG, THRB, TPO
47otosclerosis10.0TG, THRB, TPO
48muscular dystrophy-dystroglycanopathy , type a, 1010.0TG, THRB, TPO
49lobomycosis10.0ICAM1, SELE
50peritoneal mesothelioma10.0TG, THRB, TPO

Graphical network of the top 20 diseases related to Plummer's Disease:



Diseases related to plummer's disease

Symptoms & Phenotypes for Plummer's Disease

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MGI Mouse Phenotypes related to Plummer's Disease according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053799.0ICAM1, SELL, TG, THRB, TPO
2MP:00053788.4ICAM1, SELE, SELL, TG, THRB, TPO
3MP:00053978.4ICAM1, SELE, SELL, TG, THRB, TPO
4MP:00053767.6ICAM1, SELE, SELL, TG, THRB, TPO

Drugs & Therapeutics for Plummer's Disease

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Drugs for Plummer's Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 44)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Povidone-iodineapprovedPhase 416925655-41-8
Synonyms:
 
Betadine
2Antithyroid AgentsPhase 415
3Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 413168
4Hormone AntagonistsPhase 413180
5HormonesPhase 414415
6PovidonePhase 4169
7
IodinePhase 45707553-56-2807
Synonyms:
I2
Iode
Iodine-molecule
 
Iodio
Iodum
Jod
Jood
Tincture iodine
8Anti-Infective Agents, LocalPhase 41880
9Anti-Infective AgentsPhase 4, Phase 122062
10cadexomer iodinePhase 4537
11
ObinutuzumabapprovedPhase 3105949142-50-1
Synonyms:
 
Afutuzumab
12
ChlorambucilapprovedPhase 354305-03-32708
Synonyms:
23125_FLUKA
305-03-3
4-(P-Bis(beta-chloroethyl)aminophenyl)butyric acid
4-(p-bis(β-chloroethyl)aminophenyl)butyric acid
4-[p-[bis(2-chloroethyl)amino]phenyl]butyric acid
AB00051938
AC1L1EAB
AC1Q75DO
AI3-26083
Ambochlorin
Amboclorin
BPBio1_001208
BRD-K29458283-001-05-9
BRN 0999011
BSPBio_001098
BSPBio_001971
C 0253
C0253_SIGMA
C14H19Cl2NO2
CAS-305-03-3
CB 1348
CB-1348
CB1348
CCRIS 126
CHEBI:28830
CHEMBL515
CHLORAMBUCIL
CID2708
CPD000058372
Cb l348
Chlocambucil
Chloorambucol
Chlorambucil (USP/INN)
Chlorambucil [INN:BAN]
Chlorambucilum
Chlorambucilum [INN-Latin]
Chloraminophen
Chloraminophene
Chlorbutin
Chlorbutine
Chlorbutinum
Chloroambucil
Chlorobutin
Chlorobutine
Clorambucile
Clorambucile [DCIT]
Clorambucilo
Clorambucilo [INN-Spanish]
D00266
D002699
DB00291
DivK1c_000688
EINECS 206-162-0
EU-0100227
Ecloril
Elcoril
Elcorin
FT-0083565
Glaxo Wellcome Brand of Chlorambucil
GlaxoSmithKline Brand of Chlorambucil
HMS1571G20
HMS1920M15
HMS2090M19
HMS2091A22
HMS502C10
HSDB 3026
IDI1_000688
KBio1_000688
KBio2_000558
KBio2_003126
 
KBio2_005694
KBio3_001191
KBioGR_000766
KBioSS_000558
LEUKERAN (TN)
LS-1158
Leuk ersan
Leukeran
Leukeran Tablets
Leukeran tablets
Leukersan
Leukoran
Linfolizin
Linfolysin
Lopac-C-0253
Lopac0_000227
Lympholysin
MLS000028443
MLS001076130
MolPort-000-152-694
N,N-Di-2-chloroethyl-gamma-P-aminophenylbutyric acid
N,N-di-2-chloroethyl-γ-p-aminophenylbutyric acid
NCGC00015199-01
NCGC00015199-02
NCGC00015199-03
NCGC00015199-07
NCGC00015199-14
NCGC00023250-00
NCGC00023250-03
NCGC00023250-04
NCGC00023250-05
NCGC00023250-06
NCGC00023250-07
NCGC00023250-08
NCGC00023250-09
NCGC00023250-10
NCI-C03485
NCI60_002639
NINDS_000688
NSC 3088
NSC-3088
NSC3088
Pepstatin
Phenylbuttersaeure-lost
Phenylbuttersaeure-lost [German]
Phenylbutyric Acid Nitrogen Mustard
Phenylbutyric acid nitrogen mustard
Prestwick0_001079
Prestwick1_001079
Prestwick2_001079
Prestwick3_001079
RCRA waste no. U035
Rcra waste number U035
SAM002564202
SMR000058372
SPBio_000249
SPBio_002999
SPECTRUM1500171
ST50410766
Spectrum2_000065
Spectrum3_000336
Spectrum4_000273
Spectrum5_000677
Spectrum_000118
TL8002353
UNII-18D0SL7309
WLN: QV3R DN2G2G
Wellcome Brand of Chlorambucil
chlorambucil
gamma-[P-Di(2-chloroethyl)aminophenyl]butyric acid
γ-[p-di(2-chloroethyl)aminophenyl]butyric acid
13Alkylating AgentsPhase 34827
14Antineoplastic Agents, AlkylatingPhase 34603
15
Rucaparibapproved, investigationalPhase 216283173-50-29931954
Synonyms:
AG-014699
 
AG014699
PF-01367338
rucaparib
16
Salmon Calcitoninapproved, investigationalPhase 29547931-85-116129616
Synonyms:
135506-95-5
47931-85-1
Astronin
Biocalcin
Bionocalcin
C028815
C06865
C145H239N43O48S2
CALCITONIN, SALMON
Cadens
Calciben
Calcihexal
Calcimar
Calcimar (TN)
Calcimonta
Calcinil
Calcioton
Calcitonin (Salmon Synthetic)
Calcitonin (salmon)
Calcitonin 1 precursor
Calcitonin Salmon
Calcitonin [USAN:INN:BAN:JAN]
Calcitonin salmon
Calcitonin salmon (USAN/INN)
Calcitonin salmon (synthesis)
Calcitonin salmon (synthesis) (JAN)
Calcitonin salmon recombinant
Calcitonin vom lachs
Calcitonin, salmar
Calcitonin, salmon
Calcitonin, salmon, for bioassay
Calcitonin,salmon
Calcitonin-salmon
Calcitonina
Calcitonine de saumon
Calcitoran
Calco
Calogen
Calsynar
Calsynar Lyo L
Caltine
Casalm
Catonin
Cibacalcin
Cibacalcine
Citonina
 
D00249
EINECS 256-342-8
Eptacalcin
Forcaltonin
Fortical
Fortical (TN)
Ipocalcin
Isi-calcin
Kalsimin
Karil
LS-48624
Miacalcic
Miacalcin
Miacalcin (TN)
Miracalcic
Oseototal
Osseocalcina
Osteobion
Osteovis
Ostosalm
Ostostabil
Porostenina
Prontocalcin
Quosten
Riostin
Rulicalcin
Salcat
Salcatonin
Salcatyn
Salmocalcin
Salmofar
Salmon calcitonin
Salmon calcitonin I
Salmon calcitonin-(I-32)
Salmotonin
Sical
Stalcin
Staporos
Steocin
TZ-CT
Thyrocalcitonin (salmon)
Tonocalcin
UNII-7SFC6U2VI5
Ucecal
recombinant salmon calcitonin
salmon calcitonin (1-32)
synthetic salmon calcitonin
17Poly(ADP-ribose) Polymerase InhibitorsPhase 2, Phase 1340
18Calcitonin Gene-Related PeptidePhase 295
19calcitoninPhase 2107
20Bone Density Conservation AgentsPhase 23376
21ThromboplastinPhase 1, Phase 263
22ImmunoglobulinsPhase 1, Phase 26394
23AntibodiesPhase 1, Phase 26394
24
OlaparibapprovedPhase 1140763113-22-023725625
Synonyms:
4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one
4-[(3-{[4-Cyclopropylcarbonyl)piperazin-4-yl]carbonyl}-4-fluorophenyl)methyl]phtalazin-1(2H)-one
4-[3-(4-Cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one
763113-22-0
937799-91-2
AKOS005145764
AZD 2281
AZD-2281
AZD2281
 
Acylpiperazine analogue, 47
CHEMBL521686
EC-000.2324
EN002690
FT-0083489
KU-0059436
KU-59436
Olaparib
Olaparib, KU-0059436, AZD2281, KU0059436, AZD2281
S1060_Selleck
olaparib
25
GemcitabineapprovedPhase 1201895058-81-460750
Synonyms:
103882-84-4
122111-03-9
2',2'-DiF-dC
2',2'-Difluoro-2'-deoxycytidine
2',2'-Difluorodeoxycytidine
2'-Deoxy-.beta.-D-2',2'-difluorocytidine
2'-Deoxy-2',2'-difluorocytidine
4-Amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
4-Amino-1-[3,3-difluoro-4-hydroxy-5-(hydroxymethyl) tetrahydrofuran-2-yl]-1H-pyrimidin-2-one
4-amino-1-((2R,4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
95058-81-4
AB1004842
AC1L1TUQ
C07650
CCRIS 8984
CHEBI:175901
CHEMBL888
CID60750
Cytidine, 2'-deoxy-2',2'-difluoro-2'-Deoxy-.beta.-D-2',2'-difluorocytidine
D02368
DB00441
DDFC
DFDC
DFdC
DFdCyd
Folfugem
GEO
Gamcitabine
GemLip
Gemcel
 
Gemcin
Gemcitabin
Gemcitabina
Gemcitabina [INN-Spanish]
Gemcitabine
Gemcitabine (USAN/INN)
Gemcitabine HCl
Gemcitabine hydrochloride
Gemcitabine stereoisomer
Gemcitabinum
Gemcitabinum [INN-Latin]
Gemtro
Gemzar
Gemzar (hydrochloride)
HMS2089P10
HSDB 7567
Inno-D07001
LS-59139
LY 188011
LY-188011
LY188011
NCGC00168784-01
NChemBio.2007.10-comp25
NSC 613327
NSC613327
TL8005979
UNII-B76N6SBZ8R
ZINC18279854
Zefei
gemcitabine
nchembio.573-comp7
nchembio.90-comp2
26
Pemetrexedapproved, investigationalPhase 1636150399-23-8, 137281-23-3446556, 60843
Synonyms:
(2R)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid
(2S)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid
137281-23-3
150399-23-8
1juj
2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid
2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID
AC1L1U1D
AC1L2PDW
AC1L98DY
AC1L9JT6
AC1OCF51
AC1Q5R1W
Alimta
Alimta (TN)
Bio-0078
C20H19N5O6.2Na
C20H21N5O6
CHEBI:195145
CHEBI:43746
CHEBI:474008
CHEMBL1200373
CHEMBL225072
CHEMBL59843
CID125891
CID394493
CID446556
CID60843
CID6918197
D03828
D07472
DB00642
Disodium N-(p-(2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo(2,3-d)pyrimidin-5-yl)ethyl)benzoyl)-L-glutamate
 
HSDB 7316
I06-1253
I06-1294
I06-2128
L-Glutamic acid, N-(4-(2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo(2,3-d)pyrimidin-5-yl)ethyl)benzoyl)-, disodium salt
LS-172988
LS-173384
LY 231,514
LY 231514
LY-231,514
LY-2315
LY-231514
LY231514
LY231514 disodium
LYA
N-(4-(2-(2-Amino-3,4-dihydro-4-oxo-7H-pyrrolo(2,3-d)pyrimdin-5-yl)ethyl)benzoyl)glutamic acid
NCGC00167517-01
NCI60_035021
NSC698037
Pemetrexed
Pemetrexed (INN)
Pemetrexed Disodium
Pemetrexed [INN:BAN]
Pemetrexed disodium
Pemetrexed disodium (USAN)
Pemetrexed disodium [USAN]
Rolazar
ST51053024
Tifolar
UNII-04Q9AIZ7NO
UNII-2PKU919BA9
disodium (2R)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate
disodium (2S)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate
n-{4-[2-(2-amino-4-oxo-4,7-dihydro-1h-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-d-glutamic acid
nchembio.108-comp6
27
CisplatinapprovedPhase 1277015663-27-184093, 441203, 2767
Synonyms:
(SP-4-1)-diamminedichloridoplatinum
(SP-4-1)-diamminedichloroplatinum
(SP-4-2)-diamminedichloridoplatinum
(SP-4-2)-diamminedichloroplatinum
Abiplatin
Biocisplatinum
Briplatin
CACP
CDDP
CHEBI:35852
CID441203
CPD0-1392
CPDC
CPDD
Carboquone
Cis Pt II
Cis-DDP
Cis-Diaminedichloroplatinum
Cis-Diamminedichloroplatinum
Cismaplat
Cisplatine
Cisplatino
Cisplatinum
Cisplatyl
Citoplationo
DB00515
DDP
DDPT
Diamminedichloroplatinum
 
EU-0100918
Lederplatin
Neoplatin
Peyrone's chloride
Peyrone's salt
Plastin
Platamine
Platiblastin
Platidiam
Platinex
Platinol
Platinol-AQ
Platinoxan
Platinum Ammine Chloride
Platinum Ammonium Chloride
Platinum Diamine Dichloride
Randa
Trans-DDP
Trans-Diaminedichloroplatinum
Trans-Diamminedichloroplatinum
Trans-Dichlorodiammine Platinum
Trans-Platinumdiammine Dichloride
cis-DDP
cis-Diamminedichloroplatinum
cis-Dichlorodiammineplatinum(II)
cis-[PtCl2(NH3)2]
cis-diamminedichloridoplatinum(II)
cis-diamminedichloroplatinum(II)
nchembio773-comp1
trans-diamminedichloridoplatinum(II)
28
leucovorinapproved, NutraceuticalPhase 1323558-05-954575, 6560146, 143
Synonyms:
(5-formyl-5,6,7,8-tetrahydropteroyl)glutamate
(6R,S)-5-Formyltetrahydrofolate
10-Formyl-7,8-dihydrofolate
10-Formyl-7,8-dihydrofolic acid
5-Formyl-5,6,7,8-tetrahydrofolate
5-Formyl-5,6,7,8-tetrahydrofolic acid
5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid
5-Formyltetrahydrofolate
5-Formyltetrahydrofolic acid
5-Formyltetrahydropteroylglutamate
5-Formyltetrahydropteroylglutamic acid
5-formyltetrahydrofolic acid
Acide folinique
Calcium citrovorum factor
Calcium folinate
Citrovorum factor
Folinate
Folinic acid
Folinic acid calcium salt
 
Folinic acid calcium salt USP27
Folinic acid-SF
L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid
L-Leucovorin
L-N-[p-[[(2-Amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-Glutamic acid
L-leucovorin
Leucal
Leucovorin calcium
Leucovorin folinic acid
Leucovorinum
Leukovorin
Levoleucovorin
N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid
N5-Formyl-5,6,7,8-tetrahydrofolate
N5-Formyl-5,6,7,8-tetrahydrofolic acid
N5-Formyl-THF
N5-Formyltetrahydrofolate
N5-Formyltetrahydrofolic acid
Welcovorin
Wellcovorin
folinate
29
Folic Acidapproved, nutraceutical, vet_approvedPhase 1439259-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
30
Docetaxelapproved, investigational, Approved May 1996Phase 11967114977-28-5148124, 9877265
Synonyms:
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl (aR,bS)-b-[[(1,1-dimethylethoxy)carbonyl]amino]-a-hydroxybenzenepropanoate
(2alpha,5beta,7beta,10beta,13alpha)-4-(acetyloxy)-13-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7,10-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
01885_FLUKA
114977-28-5
4-(Acetyloxy)-13alpha-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7beta,10beta-trihydroxy-9-oxo-5beta,20-epoxytax-11-en-2alpha-yl benzoate
4-(acetyloxy)-13alpha-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7beta,10beta-trihydroxy-9-oxo-5beta,20-epoxytax-11-en-2alpha-yl benzoate
AC-383
AC1L3WHJ
ANX-514
BIND-014
C11231
CHEBI:4672
CHEMBL92
CID148124
D07866
DB01248
Docetaxel
Docetaxel (INN)
Docetaxel anhydrous
Docetaxel, Trihydrate
EmDOC
 
HMS2089K08
InChI=1/C43H53NO14/c1-22-26(55-37(51)32(48)30(24-15-11-9-12-16-24)44-38(52)58-39(3,4)5)20-43(53)35(56-36(50)25-17-13-10-14-18-25)33-41(8,34(49)31(47)29(22)40(43,6)7)27(46)19-28-42(33,21-54-28)57-23(2)45/h9-18,26-28,30-33,35,46-48,53H,19-21H2,1-8H3,(H,44,5
MolPort-003-847-005
N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxel
N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol
N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxel
N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol
N-debenzoyl-N-Boc-10-deacetyl taxol
NSC-628503
PSMA-targeted docetaxel nanoparticle
RP-56976
SDP-014
TXL
Taxotere
Taxotere (TN)
Taxotere(R)
XRP-6976L
docetaxel
docetaxel 114977-28-5
nchembio.188-comp8
nchembio.2007.34-comp7
nchembio.573-comp11
nchembio853-comp8
31Liver ExtractsPhase 14067
32Immunosuppressive AgentsPhase 113086
33Nucleic Acid Synthesis InhibitorsPhase 14962
34Vitamin B ComplexPhase 14337
35Antiviral AgentsPhase 19967
36AntimetabolitesPhase 112054
37Folic Acid AntagonistsPhase 12257
38Antimitotic AgentsPhase 15657
39Antimetabolites, AntineoplasticPhase 17361
40ColaNutraceuticalPhase 11946
41Vitamin B9NutraceuticalPhase 14392
42FolateNutraceuticalPhase 14392
43Peripheral Nervous System Agents23689
44Analgesics11733

Interventional clinical trials:

(show all 27)
idNameStatusNCT IDPhase
1Antithyroid Drugs During Radioiodine TherapyCompletedNCT00150137Phase 4
2Block-replacement Therapy During Radioiodine TherapyCompletedNCT00150124Phase 4
3Dilute Betadine Lavage in the Prevention of Postoperative InfectionRecruitingNCT01175044Phase 4
4A Study to Compare the Efficacy and Safety of Obinutuzumab + Venetoclax (GDC-0199) Versus Obinutuzumab + Chlorambucil in Participants With Chronic Lymphocytic LeukemiaActive, not recruitingNCT02242942Phase 3
5rhTSH, Thyroid Size, and Radioiodine Therapy in Benign GoiterCompletedNCT00145366Phase 2
6A Phase 1/2A Study of Minerval in Adult Patients With Advanced Solid TumoursCompletedNCT01792310Phase 1, Phase 2
7Rucaparib(CO-338;Formally Called AG-014699 or PF-0136738) in Treating Patients With Locally Advanced or Metastatic Breast Cancer or Advanced Ovarian CancerCompletedNCT00664781Phase 2
8Phase 1/2a Study of Oral BAL101553 in Adult Patients With Solid Tumors or Glioblastoma or High-grade GliomaRecruitingNCT02490800Phase 1, Phase 2
9Tisotumab Vedotin (HuMax®-TF-ADC) Safety Study in Patients With Solid TumorsRecruitingNCT02001623Phase 1, Phase 2
10Trial of Olaparib in Combination With AZD5363 (ComPAKT)Unknown statusNCT02338622Phase 1
11Dose Escalating Study of Foxy-5 in Breast-, Colon- or Prostate Cancer PatientsRecruitingNCT02655952Phase 1
12Safety and Tolerability of Collagenase Clostridium Histolyticum (EN3835) to Treat Uterine Leiomyoma (Fibroids)RecruitingNCT02889848Phase 1
13MSB0011359C (M7824) in Metastatic or Locally Advanced Solid TumorsRecruitingNCT02517398Phase 1
14A Phase I Trial of AZD3965 in Patients With Advanced CancerRecruitingNCT01791595Phase 1
15A Phase 1 Trial of SRA737 in Subjects With Advanced CancerRecruitingNCT02797964Phase 1
16First-in-Human Safety and Tolerability Study of MTL-CEBPA in Patients With Advanced Liver CancerRecruitingNCT02716012Phase 1
17A Clinical Study on the Safety and Efficacy of Debio 0932 in Combination With Standard of Care in Patients With Non-small Cell Lung Cancer [NSCLC]TerminatedNCT01714037Phase 1
18Opiate Sleep Disordered Breathing StudyUnknown statusNCT00791674
19Cell Phone Intervention to Support Antiretroviral Therapy (ART) Adherence in KenyaCompletedNCT00830622
20Bone Structure and Strength Evaluated by Extreme-CT Scan Before and After Treatment of Hyper- and HypothyroidismRecruitingNCT02005250
21RADAR1- Trial of a New Blood Sample Method (Remote Arthritis Disease Activity MonitoR)RecruitingNCT02809547
22Training Dual-Task Walking After StrokeRecruitingNCT01568957
23Ultrasound Appearance of the Endometrium Post Radio-Frequency AblationRecruitingNCT02584088
24Pharmacogenomics Information in Enhancing Post-operative Total Joint Replacement Pain Management: a Pilot StudyRecruitingNCT02711592
25Comparison of Three Different Pain Blocks for Subjects Undergoing VATS (Video Assisted Thoracoscopic Surgery) Procedure.RecruitingNCT03151434
26Expanding MRI Access for Patients With New and Existing ICDs and CRT-Ds ( ENABLE MRI)RecruitingNCT02652481
27ReActiv8 for Chronic Low Back PainRecruitingNCT01985230

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Genetic Tests for Plummer's Disease

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Anatomical Context for Plummer's Disease

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MalaCards organs/tissues related to Plummer's Disease:

36
Thyroid

Publications for Plummer's Disease

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Articles related to Plummer's Disease:

(show all 30)
idTitleAuthorsYear
1
Thyroid cancer in Plummer's disease. (23456166)
2013
2
Intra-thyroid blood flow in Plummer's disease. (18520123)
2008
3
Evidence-based management of toxic multinodular goiter (Plummer's Disease). (18357484)
2008
4
Ventricular dysfunction in a patient with Plummer's disease: a case report. (12027234)
2002
5
Generalized granuloma annulare associated with Plummer's disease. (12224712)
2002
6
Current treatment of nodular goiter with hyperthyroidism (Plummer's disease): surgery versus radioiodine. (12490836)
2002
7
Radioiodine therapy for Plummer's disease based on the thyroid uptake of technetium-99m pertechnetate. (11007508)
2000
8
Plummer's disease with spontaneous progression to hypothyroidism. (10656280)
1999
9
Diagnostic items and treatment of Plummer's disease: a study on 180 patients. (9842101)
1998
10
Radioiodine treatment of Plummer's disease. (9867200)
1998
11
Differentiated operative therapy of thyroid autonomy (Plummer's disease). (9867204)
1998
12
Delayed radioiodine organification in Plummer's disease. (7750210)
1995
13
Concurrent Plummer's disease and parathyroid adenoma. Diagnostic and therapeutic approaches to a difficult clinical problem. (8062469)
1994
14
Symptomatology of Graves' disease and Plummer's disease in relation to age and thyroid hormone level. (8377872)
1993
15
Unusual thyroid scintigrams in Plummer's disease during methimazole therapy. (2044327)
1991
16
Unusual thyroid scintigrams in Plummer's disease during methimazole therapy. Conversion of hot to hypofunctional nodules. (2102667)
1990
17
Plummer's disease. (3145821)
1988
18
Long-term follow-up of patients with residual thyroid autonomy after surgical treatment of Plummer's disease. (2484893)
1988
19
Use of ultrasonography to eliminate hemiagenesis of a thyroid lobe in the differential diagnosis of a toxic adenoma (Plummer's disease) (3280210)
1988
20
Coexistence of a nonfunctioning thyroid nodule in Plummer's disease demonstrated by thallium-201 imaging. (3349711)
1988
21
Plummer's disease: localized thyroid autonomy. (3294993)
1987
22
Long-term follow-up in untreated Plummer's disease (autonomous goiter). (3829547)
1987
23
Treatment of toxic multinodular goiter (Plummer's disease): surgery or radioiodine? (3751092)
1986
24
Long-term follow-up after iodine-131 treatment for Plummer's disease (autonomous goiter). (3922656)
1985
25
Autoimmunity and the pathogenesis of localized thyroid autonomy (Plummer's disease). (2869844)
1985
26
Is partial thyroidectomy definitive treatment for Plummer's disease (autonomous goiter)? (6825357)
1983
27
On the natural history of Plummer's disease. (582300)
1979
28
Thyroid autonomy (Plummer's disease) with contralateral malignancy--mere coincidence? (1015361)
1976
29
Plummer's disease. (1099364)
1975
30
Nodular toxic goiter (Plummer's disease) in a child. (12119925)
1974

Variations for Plummer's Disease

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Expression for genes affiliated with Plummer's Disease

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Search GEO for disease gene expression data for Plummer's Disease.

Pathways for genes affiliated with Plummer's Disease

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GO Terms for genes affiliated with Plummer's Disease

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Biological processes related to Plummer's Disease according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hormone biosynthetic processGO:004244610.3TG, TPO
2heterophilic cell-cell adhesion via plasma membrane cell adhesion moleculesGO:000715710.0ICAM1, SELE
3leukocyte cell-cell adhesionGO:000715910.0ICAM1, SELE
4leukocyte migrationGO:00509008.9ICAM1, SELE, SELL

Sources for Plummer's Disease

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet