MCID: PLM011
MIFTS: 21

Plummer's Disease malady

Summaries for Plummer's Disease

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33MalaCards
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MalaCards: Plummer's Disease, also known as toxic nodular goiter, is related to nodular goiter and graves' disease. An important gene associated with Plummer's Disease is TDG (thymine-DNA glycosylase). Affiliated tissues include thyroid and tongue.

Aliases & Classifications for Plummer's Disease

Sources:
8Disease Ontology, 61UMLS, 45Novoseek, 57SNOMED-CT, 40NCIt, 27ICD9CM
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Aliases & Descriptions:

plummer's disease 8
toxic nodular goiter 8 61
toxic nodular goiter unspecified 8
toxic nodular goiter nos 8
goiter toxic nodular 45


External Ids:

Disease Ontology8 DOID:11277
NCIt40 C35171
ICD9CM27 242.3

Related Diseases for Plummer's Disease

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Plummer's Disease via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 14)
idRelated DiseaseScoreTop Affiliating Genes
1nodular goiter11.0
2graves' disease10.8
3multinodular goiter10.4
4adenoma10.4
5nontoxic goiter10.2
6autoimmune thyroiditis10.2
7primary hyperparathyroidism10.2
8iodine hypothyroidism10.2
9toxic diffuse goiter10.2
10thyroid cancer10.2
11thyroiditis10.2
12thyrotoxicosis10.2
13thymic hyperplasia10.2
14hypothyroidism, autoimmune10.2

Graphical network of diseases related to Plummer's Disease:



Diseases related to plummer's disease

Clinical Features for Plummer's Disease

Drugs & Therapeutics for Plummer's Disease

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

Search CenterWatch for Plummer's Disease

Drug clinical trials:

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Search CenterWatch for Plummer's Disease

Genetic Tests for Plummer's Disease

Anatomical Context for Plummer's Disease

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33MalaCards
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MalaCards organs/tissues related to Plummer's Disease:

33
Thyroid, Tongue

Animal Models for Plummer's Disease or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Plummer's Disease

Sources:
51PubMed
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Articles related to Plummer's Disease:

(show all 15)
idTitleAuthorsYear
1
Plummer Vinson syndrome association with coeliac disease. (24433651)
2013
2
Celiac disease presenting as Plummer-Vinson syndrome. (21049422)
2010
3
Plummer-Vinson syndrome associated with celiac disease and complicated by postcricoid carcinoma and carcinoma of the tongue. (12809857)
2003
4
Current treatment of nodular goiter with hyperthyroidism (Plummer's disease): surgery versus radioiodine. (12490836)
2002
5
Celiac disease presenting as the Paterson-Brown Kelly (Plummer-Vinson) syndrome. (10022662)
1999
6
Plummer-Vinson syndrome and postcricoid carcinoma: late complications of unrecognized celiac disease. (10406289)
1999
7
Plummer's disease with spontaneous progression to hypothyroidism. (10656280)
1999
8
Diagnostic items and treatment of Plummer's disease: a study on 180 patients. (9842101)
1998
9
Symptomatology of Graves' disease and Plummer's disease in relation to age and thyroid hormone level. (8377872)
1993
10
Unusual thyroid scintigrams in Plummer's disease during methimazole therapy. (2044327)
1991
11
Unusual thyroid scintigrams in Plummer's disease during methimazole therapy. Conversion of hot to hypofunctional nodules. (2102667)
1990
12
Long-term follow-up of patients with residual thyroid autonomy after surgical treatment of Plummer's disease. (2484893)
1988
13
Treatment of toxic multinodular goiter (Plummer's disease): surgery or radioiodine? (3751092)
1986
14
The Plummer-Vinson syndrome. A cutaneous manifestation of internal disease. (5026681)
1972
15
Relation between SjAPgren's disease, the Plummer-Vinson syndrome, and ariboflavinosis. (20250971)
1947

Genetic Variations for Plummer's Disease

Expression for genes affiliated with Plummer's Disease

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Plummer's Disease

Search GEO for disease gene expression data for Plummer's Disease.

Pathways for genes affiliated with Plummer's Disease

Compounds for genes affiliated with Plummer's Disease

GO Terms for genes affiliated with Plummer's Disease

Products for genes affiliated with Plummer's Disease

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Plummer's Disease

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet