MCID: PLM011
MIFTS: 38

Plummer's Disease malady

Category: Endocrine diseases

Aliases & Classifications for Plummer's Disease

About this section

Aliases & Descriptions for Plummer's Disease:

Name: Plummer's Disease 11 13
Toxic Nodular Goiter 11 67
Toxic Nodular Goiter Unspecified 11
 
Toxic Nodular Goiter Nos 11
Goiter Toxic Nodular 49
Plummer Disease 11

Classifications:



External Ids:

Disease Ontology11 DOID:11277
ICD1029 E05.2
ICD9CM31 242.3
NCIt44 C35171

Summaries for Plummer's Disease

About this section
MalaCards based summary: Plummer's Disease, also known as toxic nodular goiter, is related to nodular goiter and goiter, and has symptoms including cushingoid facies An important gene associated with Plummer's Disease is TG (Thyroglobulin), and among its related pathways are Thyroxine (Thyroid Hormone) Production and Thromboxane A2 receptor signaling. Affiliated tissues include thyroid, bone and liver, and related mouse phenotypes are endocrine/exocrine gland and growth/size/body region.

Related Diseases for Plummer's Disease

About this section

Diseases related to Plummer's Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 70)
idRelated DiseaseScoreTop Affiliating Genes
1nodular goiter31.9SHBG, TG, TPO
2goiter10.6
3iatrogenic or traumatic pituitary deficiency10.4TG, TPO
4ovarian endometrioid cystadenoma10.4TG, TPO
5rhabdomyosarcoma, embryonal, 210.4TG, TPO
6crohn's disease of the esophagus10.4TG, TPO
7nodular prostate10.4TG, TPO
8chronic frontal sinusitis10.4TG, TPO
9hypothryoidism, congenital, nongoitrous 410.4TG, TPO
10graves' disease10.3
11dysautonomia, familial10.3TG, TPO
12meningovascular neurosyphilis10.3TG, TPO
13deafness, autosomal recessive 4, with enlarged vestibular aqueduct10.3TG, TPO
14malignant mediastinum hemangiopericytoma10.3TG, TPO
15thyroiditis10.3
16shwartzman phenomenon10.2ICAM1, SELL
17primary bacterial infectious disease10.2TG, TPO
18hereditary conventional renal cell carcinoma10.2TG, TPO
19kidney benign neoplasm10.2TG, TPO
20angioedema10.2ICAM1, SELL
21acute dacryocystitis10.2ICAM1, SELL
22oppositional defiant disorder10.2ICAM1, SELL
23parasitic helminthiasis infectious disease10.2ICAM1, SELE
24lymphomatoid papulosis10.1ICAM1, SELE
25marginal corneal ulcer10.1ICAM1, SELE
26rhizomelic pseudopolyarthritis10.1ICAM1, SELE
27hashimoto thyroiditis10.1TG, TPO
28hyperthyroidism10.1
29posterolateral myocardial infarction10.1ICAM1, SELE
30cysticercosis10.1ICAM1, SELE
31psychosexual disorder10.1ICAM1, SELL
32spastic paraplegia-paget disease of bone syndrome10.1ICAM1, SELE
33louping ill10.1ICAM1, SELL
34chromoblastomycosis10.1ICAM1, SELE
35intraneural perineurioma10.1ICAM1, SELE
36blood group incompatibility10.1TG, TPO
37developmental coordination disorder10.1ICAM1, SELE
38acquired gastric outlet stenosis10.1SELE, SELL
39labyrinthine bilateral reactive loss10.1ICAM1, SELE
40dementia - subcortical10.0ICAM1, SELE
41hypocomplementemic urticarial vasculitis syndrome10.0SHBG, TG
42cd3zeta deficiency10.0ICAM1, TG, TPO
43intermittent proptosis10.0ICAM1, TG, TPO
44central gyrate choroidal dystrophy10.0SELE, SELL
45lung occult adenocarcinoma10.0SHBG, TG
46wissler's syndrome10.0ICAM1, SELE
47lung occult large cell carcinoma10.0TG, THRB, TPO
48echinostomiasis10.0TG, THRB, TPO
49frontotemporal dementia and/or amyotrophic lateral sclerosis 410.0TG, THRB, TPO
50atheroembolism of kidney10.0TG, THRB, TPO

Graphical network of the top 20 diseases related to Plummer's Disease:



Diseases related to plummer's disease

Symptoms for Plummer's Disease

About this section

UMLS symptoms related to Plummer's Disease:


cushingoid facies

Drugs & Therapeutics for Plummer's Disease

About this section

Drugs for Plummer's Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 49)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Povidone-iodineapprovedPhase 415525655-41-8
Synonyms:
 
Betadine
2Antithyroid AgentsPhase 414
3Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 1, Phase 212767
4Hormone AntagonistsPhase 4, Phase 1, Phase 212778
5HormonesPhase 4, Phase 1, Phase 213979
6PovidonePhase 4157
7
IodinePhase 45467553-56-2807
Synonyms:
I2
Iode
Iodine-molecule
 
Iodio
Iodum
Jod
Jood
Tincture iodine
8cadexomer iodinePhase 4514
9Anti-Infective AgentsPhase 4, Phase 121402
10Anti-Infective Agents, LocalPhase 41785
11
Salmon Calcitoninapproved, investigationalPhase 29147931-85-116129616
Synonyms:
135506-95-5
47931-85-1
Astronin
Biocalcin
Bionocalcin
C028815
C06865
C145H239N43O48S2
CALCITONIN, SALMON
Cadens
Calciben
Calcihexal
Calcimar
Calcimar (TN)
Calcimonta
Calcinil
Calcioton
Calcitonin (Salmon Synthetic)
Calcitonin (salmon)
Calcitonin 1 precursor
Calcitonin Salmon
Calcitonin [USAN:INN:BAN:JAN]
Calcitonin salmon
Calcitonin salmon (USAN/INN)
Calcitonin salmon (synthesis)
Calcitonin salmon (synthesis) (JAN)
Calcitonin salmon recombinant
Calcitonin vom lachs
Calcitonin, salmar
Calcitonin, salmon
Calcitonin, salmon, for bioassay
Calcitonin,salmon
Calcitonin-salmon
Calcitonina
Calcitonine de saumon
Calcitoran
Calco
Calogen
Calsynar
Calsynar Lyo L
Caltine
Casalm
Catonin
Cibacalcin
Cibacalcine
Citonina
 
D00249
EINECS 256-342-8
Eptacalcin
Forcaltonin
Fortical
Fortical (TN)
Ipocalcin
Isi-calcin
Kalsimin
Karil
LS-48624
Miacalcic
Miacalcin
Miacalcin (TN)
Miracalcic
Oseototal
Osseocalcina
Osteobion
Osteovis
Ostosalm
Ostostabil
Porostenina
Prontocalcin
Quosten
Riostin
Rulicalcin
Salcat
Salcatonin
Salcatyn
Salmocalcin
Salmofar
Salmon calcitonin
Salmon calcitonin I
Salmon calcitonin-(I-32)
Salmotonin
Sical
Stalcin
Staporos
Steocin
TZ-CT
Thyrocalcitonin (salmon)
Tonocalcin
UNII-7SFC6U2VI5
Ucecal
recombinant salmon calcitonin
salmon calcitonin (1-32)
synthetic salmon calcitonin
12
Rucaparibapproved, investigationalPhase 214283173-50-29931954
Synonyms:
AG-014699
 
AG014699
PF-01367338
rucaparib
13
Letrozoleapproved, investigationalPhase 1, Phase 2382112809-51-53902
Synonyms:
1-[Bis-(4-cyanophenyl)methyl]-1,2,4-triazole
1-[bis(4-cyanophenyl)methyl]-1,2,4-triazole
112809-51-5
4,4'-((1h-1,2,4-triazol-1-yl)methylene)dibenzonitrile
4,4'-(1H-1,2,4-Triazol-1-ylmethylene)dibenzonitrile
4,4'-(1H-1,2,4-triazol-1-yl-methylene)-bis(benzonitrile)
4,4'-(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitrile
4,4'-(1H-1,2,4-triazol-1-ylmethylene)bis-Benzonitrile Letrozole
4,4'-(1h-1,2,4-triazol-1-ylmethylene) bis-benzonitrile
4,4'-(1h-1,2,4-triazol-1-ylmethylene)bis-benzonitrile
4,4'-(1h-1,2,4-triazol-1-ylmethylene)bisbenzonitrile
4-[(4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl]benzonitrile
AB00514009
AC-1193
AC1L1GYT
AKOS005145822
BIDD:GT0015
BIDD:PXR0130
BPBio1_001331
BRD-K88789588-001-03-2
BSPBio_001209
Bio-0057
C067431
C08163
C17H11N5
CAS-112809-51-5
CCRIS 8822
CGS 20267
CGS 20267, Femara, Piroxicam, Letrozole
CGS-20267
CHEBI:6413
CHEMBL1444
CID3902
CPD000466343
D00964
 
DB01006
FEM-345
Femara
Femara (TN)
Femera
HMS1571M11
HMS2051E08
HMS2089L22
HSDB 7461
I06-0022
LS-38788
Letoval
Letrozol
Letrozole
Letrozole (JAN/USP/INN)
Letrozole [USAN:INN]
MLS000759455
MLS001424038
MLS002584991
MolPort-003-848-373
NCGC00016973-01
NCGC00016973-02
NSC719345
Novartis Brand of Letrozole
Prestwick0_001025
Prestwick1_001025
Prestwick2_001025
Prestwick3_001025
S1235_Selleck
SAM001246649
SMR000466343
SPBio_003070
TL8000371
UNII-7LKK855W8I
ZINC03778874
letrozole
14
Anastrozoleapproved, investigationalPhase 1, Phase 2272120511-73-12187
Synonyms:
.alpha.,alpha.,.alpha.',.alpha.'-tetramethyl-5(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
1,3-benzenediacetonitrile, a, a, a', a'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)
120511-73-1
2,2'-(5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene)bis(2-methylpropionitrile)
2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]bis(2-methylpropanenitrile)
2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)benzene-1,3-diyl]bis(2-methylpropanenitrile)
2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile
AC-4234
AC1L1D49
Anastrazole
Anastrole
Anastrozol
Anastrozole (JAN/USAN/INN)
Anastrozole [USAN:INN:BAN]
Arimidex
Arimidex (TN)
Arimidex (Zeneca)
Arimidex, Anastrozole
Asiolex
Astra brand of anastrozole
AstraZeneca brand of anastrozole
C08159
C090450
C17H19N5
CHEBI:2704
CHEMBL1399
CID2187
CPD000466301
 
D00960
DB01217
HMS2052M11
HMS2089N10
HSDB 7462
I06-0021
ICI D1033
ICI-D 1033
ICI-D1033
LS-29563
MLS000759396
MLS001424217
MolPort-005-933-078
NCGC00164619-01
NSC719344
S1188_Selleck
SAM001246525
SBB066057
SMR000466301
UNII-2Z07MYW1AZ
ZD 1033
ZD-1033
ZD1033
ZINC00000941
Zeneca ZD 1033
Zeneca brand of anastrozole
alpha,alpha,Alpha',alpha'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
alpha,alpha,alpha',alpha'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
anastrazole
anastrozole
15Bone Density Conservation AgentsPhase 23266
16calcitoninPhase 2103
17Poly(ADP-ribose) Polymerase InhibitorsPhase 2309
18Calcitonin Gene-Related PeptidePhase 291
19Steroid Synthesis InhibitorsPhase 1, Phase 21718
20ThromboplastinPhase 1, Phase 260
21AntibodiesPhase 1, Phase 26045
22ImmunoglobulinsPhase 1, Phase 26045
23EstrogensPhase 1, Phase 22470
24Aromatase InhibitorsPhase 1, Phase 2807
25Antineoplastic Agents, HormonalPhase 1, Phase 25407
26Estrogen AntagonistsPhase 1, Phase 21315
27
CisplatinapprovedPhase 1269015663-27-184093, 441203, 2767
Synonyms:
(SP-4-1)-diamminedichloridoplatinum
(SP-4-1)-diamminedichloroplatinum
(SP-4-2)-diamminedichloridoplatinum
(SP-4-2)-diamminedichloroplatinum
Abiplatin
Biocisplatinum
Briplatin
CACP
CDDP
CHEBI:35852
CID441203
CPD0-1392
CPDC
CPDD
Carboquone
Cis Pt II
Cis-DDP
Cis-Diaminedichloroplatinum
Cis-Diamminedichloroplatinum
Cismaplat
Cisplatine
Cisplatino
Cisplatinum
Cisplatyl
Citoplationo
DB00515
DDP
DDPT
Diamminedichloroplatinum
 
EU-0100918
Lederplatin
Neoplatin
Peyrone's chloride
Peyrone's salt
Plastin
Platamine
Platiblastin
Platidiam
Platinex
Platinol
Platinol-AQ
Platinoxan
Platinum Ammine Chloride
Platinum Ammonium Chloride
Platinum Diamine Dichloride
Randa
Trans-DDP
Trans-Diaminedichloroplatinum
Trans-Diamminedichloroplatinum
Trans-Dichlorodiammine Platinum
Trans-Platinumdiammine Dichloride
cis-DDP
cis-Diamminedichloroplatinum
cis-Dichlorodiammineplatinum(II)
cis-[PtCl2(NH3)2]
cis-diamminedichloridoplatinum(II)
cis-diamminedichloroplatinum(II)
nchembio773-comp1
trans-diamminedichloridoplatinum(II)
28
GemcitabineapprovedPhase 1197495058-81-460750
Synonyms:
103882-84-4
122111-03-9
2',2'-DiF-dC
2',2'-Difluoro-2'-deoxycytidine
2',2'-Difluorodeoxycytidine
2'-Deoxy-.beta.-D-2',2'-difluorocytidine
2'-Deoxy-2',2'-difluorocytidine
4-Amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
4-Amino-1-[3,3-difluoro-4-hydroxy-5-(hydroxymethyl) tetrahydrofuran-2-yl]-1H-pyrimidin-2-one
4-amino-1-((2R,4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
95058-81-4
AB1004842
AC1L1TUQ
C07650
CCRIS 8984
CHEBI:175901
CHEMBL888
CID60750
Cytidine, 2'-deoxy-2',2'-difluoro-2'-Deoxy-.beta.-D-2',2'-difluorocytidine
D02368
DB00441
DDFC
DFDC
DFdC
DFdCyd
Folfugem
GEO
Gamcitabine
GemLip
Gemcel
 
Gemcin
Gemcitabin
Gemcitabina
Gemcitabina [INN-Spanish]
Gemcitabine
Gemcitabine (USAN/INN)
Gemcitabine HCl
Gemcitabine hydrochloride
Gemcitabine stereoisomer
Gemcitabinum
Gemcitabinum [INN-Latin]
Gemtro
Gemzar
Gemzar (hydrochloride)
HMS2089P10
HSDB 7567
Inno-D07001
LS-59139
LY 188011
LY-188011
LY188011
NCGC00168784-01
NChemBio.2007.10-comp25
NSC 613327
NSC613327
TL8005979
UNII-B76N6SBZ8R
ZINC18279854
Zefei
gemcitabine
nchembio.573-comp7
nchembio.90-comp2
29
Pemetrexedapproved, investigationalPhase 1617150399-23-8, 137281-23-3446556, 60843
Synonyms:
(2R)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid
(2S)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid
137281-23-3
150399-23-8
1juj
2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid
2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID
AC1L1U1D
AC1L2PDW
AC1L98DY
AC1L9JT6
AC1OCF51
AC1Q5R1W
Alimta
Alimta (TN)
Bio-0078
C20H19N5O6.2Na
C20H21N5O6
CHEBI:195145
CHEBI:43746
CHEBI:474008
CHEMBL1200373
CHEMBL225072
CHEMBL59843
CID125891
CID394493
CID446556
CID60843
CID6918197
D03828
D07472
DB00642
Disodium N-(p-(2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo(2,3-d)pyrimidin-5-yl)ethyl)benzoyl)-L-glutamate
 
HSDB 7316
I06-1253
I06-1294
I06-2128
L-Glutamic acid, N-(4-(2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo(2,3-d)pyrimidin-5-yl)ethyl)benzoyl)-, disodium salt
LS-172988
LS-173384
LY 231,514
LY 231514
LY-231,514
LY-2315
LY-231514
LY231514
LY231514 disodium
LYA
N-(4-(2-(2-Amino-3,4-dihydro-4-oxo-7H-pyrrolo(2,3-d)pyrimdin-5-yl)ethyl)benzoyl)glutamic acid
NCGC00167517-01
NCI60_035021
NSC698037
Pemetrexed
Pemetrexed (INN)
Pemetrexed Disodium
Pemetrexed [INN:BAN]
Pemetrexed disodium
Pemetrexed disodium (USAN)
Pemetrexed disodium [USAN]
Rolazar
ST51053024
Tifolar
UNII-04Q9AIZ7NO
UNII-2PKU919BA9
disodium (2R)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate
disodium (2S)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate
n-{4-[2-(2-amino-4-oxo-4,7-dihydro-1h-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-d-glutamic acid
nchembio.108-comp6
30
Folic Acidapproved, nutraceutical, vet_approvedPhase 1427959-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
31
Docetaxelapproved, investigational, Approved May 1996Phase 11918114977-28-5148124, 9877265
Synonyms:
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl (aR,bS)-b-[[(1,1-dimethylethoxy)carbonyl]amino]-a-hydroxybenzenepropanoate
(2alpha,5beta,7beta,10beta,13alpha)-4-(acetyloxy)-13-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7,10-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
01885_FLUKA
114977-28-5
4-(Acetyloxy)-13alpha-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7beta,10beta-trihydroxy-9-oxo-5beta,20-epoxytax-11-en-2alpha-yl benzoate
4-(acetyloxy)-13alpha-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7beta,10beta-trihydroxy-9-oxo-5beta,20-epoxytax-11-en-2alpha-yl benzoate
AC-383
AC1L3WHJ
ANX-514
BIND-014
C11231
CHEBI:4672
CHEMBL92
CID148124
D07866
DB01248
Docetaxel
Docetaxel (INN)
Docetaxel anhydrous
Docetaxel, Trihydrate
EmDOC
 
HMS2089K08
InChI=1/C43H53NO14/c1-22-26(55-37(51)32(48)30(24-15-11-9-12-16-24)44-38(52)58-39(3,4)5)20-43(53)35(56-36(50)25-17-13-10-14-18-25)33-41(8,34(49)31(47)29(22)40(43,6)7)27(46)19-28-42(33,21-54-28)57-23(2)45/h9-18,26-28,30-33,35,46-48,53H,19-21H2,1-8H3,(H,44,5
MolPort-003-847-005
N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxel
N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol
N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxel
N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol
N-debenzoyl-N-Boc-10-deacetyl taxol
NSC-628503
PSMA-targeted docetaxel nanoparticle
RP-56976
SDP-014
TXL
Taxotere
Taxotere (TN)
Taxotere(R)
XRP-6976L
docetaxel
docetaxel 114977-28-5
nchembio.188-comp8
nchembio.2007.34-comp7
nchembio.573-comp11
nchembio853-comp8
32Antiviral AgentsPhase 19732
33AntimetabolitesPhase 111774
34Antimetabolites, AntineoplasticPhase 17171
35Immunosuppressive AgentsPhase 112770
36Liver ExtractsPhase 13868
37Nucleic Acid Synthesis InhibitorsPhase 14855
38Vitamin B ComplexPhase 14229
39Folic Acid AntagonistsPhase 12200
40Antimitotic AgentsPhase 15498
41ColaNutraceuticalPhase 11881
42Vitamin B9NutraceuticalPhase 14279
43Folinic AcidNutraceuticalPhase 13150
44FolateNutraceuticalPhase 14279
45Peripheral Nervous System Agents22776
46Analgesics11287
47Antibiotics, Antitubercular6972
48Anti-Bacterial Agents10884
49Antitubercular Agents1272

Interventional clinical trials:

(show all 23)
idNameStatusNCT IDPhase
1Antithyroid Drugs During Radioiodine TherapyCompletedNCT00150137Phase 4
2Block-replacement Therapy During Radioiodine TherapyCompletedNCT00150124Phase 4
3Dilute Betadine Lavage in the Prevention of Postoperative InfectionRecruitingNCT01175044Phase 4
4rhTSH, Thyroid Size, and Radioiodine Therapy in Benign GoiterCompletedNCT00145366Phase 2
5A Phase 1/2A Study of Minerval in Adult Patients With Advanced Solid TumoursCompletedNCT01792310Phase 1, Phase 2
6Rucaparib(CO-338;Formally Called AG-014699 or PF-0136738) in Treating Patients With Locally Advanced or Metastatic Breast Cancer or Advanced Ovarian CancerCompletedNCT00664781Phase 2
7Phase 1/2a Study of Oral BAL101553 in Adult Patients With Solid Tumors or Glioblastoma or High-grade GliomaRecruitingNCT02490800Phase 1, Phase 2
8AZD4547 & Anastrozole or Letrozole (NSAIs) in ER+ Breast Cancer Patients Who Have Progressed on NSAIs (RADICAL)RecruitingNCT01791985Phase 1, Phase 2
9Tisotumab Vedotin (HuMax®-TF-ADC) Safety Study in Patients With Solid TumorsRecruitingNCT02001623Phase 1, Phase 2
10Dose Escalating Study of Foxy-5 in Breast-, Colon- or Prostate Cancer PatientsRecruitingNCT02655952Phase 1
11Safety and Tolerability of Collagenase Clostridium Histolyticum (EN3835) to Treat Uterine Leiomyoma (Fibroids)RecruitingNCT02889848Phase 1
12A Phase I Trial of AZD3965 in Patients With Advanced CancerRecruitingNCT01791595Phase 1
13A Phase I Trial of CCT245737 in Combination With Gemcitabine Plus Cisplatin or Gemcitabine Alone in Patients With Advanced CancerRecruitingNCT02797977Phase 1
14First-in-Human Safety and Tolerability Study of MTL-CEBPA in Patients With Advanced Liver CancerRecruitingNCT02716012Phase 1
15A Clinical Study on the Safety and Efficacy of Debio 0932 in Combination With Standard of Care in Patients With Non-small Cell Lung Cancer [NSCLC]TerminatedNCT01714037Phase 1
16Cell Phone Intervention to Support Antiretroviral Therapy (ART) Adherence in KenyaCompletedNCT00830622
17Bone Structure and Strength Evaluated by Extreme-CT Scan Before and After Treatment of Hyper- and HypothyroidismRecruitingNCT02005250
18RADAR1- Trial of a New Blood Sample Method (Remote Arthritis Disease Activity MonitoR)RecruitingNCT02809547
19Oral Antibiotics After 2-Stage Revision for Infected Total Hip Arthroplasty and Total Knee ArthroplastyRecruitingNCT01760863
20Training Dual-Task Walking After StrokeRecruitingNCT01568957
21Ultrasound Appearance of the Endometrium Post Radio-Frequency AblationRecruitingNCT02584088
22Pharmacogenomics Information in Enhancing Post-operative Total Joint Replacement Pain Management: a Pilot StudyRecruitingNCT02711592
23ReActiv8 for Chronic Low Back PainRecruitingNCT01985230

Search NIH Clinical Center for Plummer's Disease

Genetic Tests for Plummer's Disease

About this section

Anatomical Context for Plummer's Disease

About this section

MalaCards organs/tissues related to Plummer's Disease:

35
Thyroid, Bone, Liver, Prostate, Colon, Lung

Animal Models for Plummer's Disease or affiliated genes

About this section

MGI Mouse Phenotypes related to Plummer's Disease:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053799.0ICAM1, SELL, TG, THRB, TPO
2MP:00053788.4ICAM1, SELE, SELL, TG, THRB, TPO
3MP:00053978.4ICAM1, SELE, SELL, TG, THRB, TPO
4MP:00053767.6ICAM1, SELE, SELL, TG, THRB, TPO

Publications for Plummer's Disease

About this section

Articles related to Plummer's Disease:

(show all 30)
idTitleAuthorsYear
1
Thyroid cancer in Plummer's disease. (23456166)
2013
2
Intra-thyroid blood flow in Plummer's disease. (18520123)
2008
3
Evidence-based management of toxic multinodular goiter (Plummer's Disease). (18357484)
2008
4
Generalized granuloma annulare associated with Plummer's disease. (12224712)
2002
5
Ventricular dysfunction in a patient with Plummer's disease: a case report. (12027234)
2002
6
Current treatment of nodular goiter with hyperthyroidism (Plummer's disease): surgery versus radioiodine. (12490836)
2002
7
Radioiodine therapy for Plummer's disease based on the thyroid uptake of technetium-99m pertechnetate. (11007508)
2000
8
Plummer's disease with spontaneous progression to hypothyroidism. (10656280)
1999
9
Differentiated operative therapy of thyroid autonomy (Plummer's disease). (9867204)
1998
10
Diagnostic items and treatment of Plummer's disease: a study on 180 patients. (9842101)
1998
11
Radioiodine treatment of Plummer's disease. (9867200)
1998
12
Delayed radioiodine organification in Plummer's disease. (7750210)
1995
13
Concurrent Plummer's disease and parathyroid adenoma. Diagnostic and therapeutic approaches to a difficult clinical problem. (8062469)
1994
14
Symptomatology of Graves' disease and Plummer's disease in relation to age and thyroid hormone level. (8377872)
1993
15
Unusual thyroid scintigrams in Plummer's disease during methimazole therapy. (2044327)
1991
16
Unusual thyroid scintigrams in Plummer's disease during methimazole therapy. Conversion of hot to hypofunctional nodules. (2102667)
1990
17
Coexistence of a nonfunctioning thyroid nodule in Plummer's disease demonstrated by thallium-201 imaging. (3349711)
1988
18
Plummer's disease. (3145821)
1988
19
Long-term follow-up of patients with residual thyroid autonomy after surgical treatment of Plummer's disease. (2484893)
1988
20
Use of ultrasonography to eliminate hemiagenesis of a thyroid lobe in the differential diagnosis of a toxic adenoma (Plummer's disease) (3280210)
1988
21
Plummer's disease: localized thyroid autonomy. (3294993)
1987
22
Long-term follow-up in untreated Plummer's disease (autonomous goiter). (3829547)
1987
23
Treatment of toxic multinodular goiter (Plummer's disease): surgery or radioiodine? (3751092)
1986
24
Autoimmunity and the pathogenesis of localized thyroid autonomy (Plummer's disease). (2869844)
1985
25
Long-term follow-up after iodine-131 treatment for Plummer's disease (autonomous goiter). (3922656)
1985
26
Is partial thyroidectomy definitive treatment for Plummer's disease (autonomous goiter)? (6825357)
1983
27
On the natural history of Plummer's disease. (582300)
1979
28
Thyroid autonomy (Plummer's disease) with contralateral malignancy--mere coincidence? (1015361)
1976
29
Plummer's disease. (1099364)
1975
30
Nodular toxic goiter (Plummer's disease) in a child. (12119925)
1974

Variations for Plummer's Disease

About this section

Expression for genes affiliated with Plummer's Disease

About this section
Search GEO for disease gene expression data for Plummer's Disease.

Pathways for genes affiliated with Plummer's Disease

About this section

GO Terms for genes affiliated with Plummer's Disease

About this section

Cellular components related to Plummer's Disease according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056158.6ICAM1, SELE, TG, TPO

Biological processes related to Plummer's Disease according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1leukocyte cell-cell adhesionGO:00071599.8ICAM1, SELE
2heterophilic cell-cell adhesion via plasma membrane cell adhesion moleculesGO:00071579.7ICAM1, SELE
3hormone biosynthetic processGO:00424469.6TG, TPO
4thyroid hormone generationGO:00065909.4TG, TPO
5response to lipopolysaccharideGO:00324969.2ICAM1, SELE, TG
6leukocyte migrationGO:00509008.9ICAM1, SELE, SELL

Sources for Plummer's Disease

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet