MCID: PNM013
MIFTS: 41

Pneumococcal Meningitis malady

Categories: Neuronal diseases, Infectious diseases, Rare diseases

Aliases & Classifications for Pneumococcal Meningitis

Aliases & Descriptions for Pneumococcal Meningitis:

Name: Pneumococcal Meningitis 56
Meningitis, Pneumococcal 69

Classifications:



External Ids:

Orphanet 56 ORPHA55655
ICD10 via Orphanet 34 G00.1
MESH via Orphanet 43 D008586
UMLS via Orphanet 70 C0025295
ICD10 33 G00.1

Summaries for Pneumococcal Meningitis

MalaCards based summary : Pneumococcal Meningitis, also known as meningitis, pneumococcal, is related to meningitis and cerebritis. An important gene associated with Pneumococcal Meningitis is MMP9 (Matrix Metallopeptidase 9), and among its related pathways/superpathways are Innate Immune System and Phagosome. The drugs Phenytoin and Acetaminophen have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and neutrophil, and related phenotypes are hematopoietic system and homeostasis/metabolism

Related Diseases for Pneumococcal Meningitis

Diseases related to Pneumococcal Meningitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 77)
id Related Disease Score Top Affiliating Genes
1 meningitis 11.0
2 cerebritis 10.2
3 pneumonia 10.1
4 neuronitis 10.1
5 polyneuropathy in collagen vascular disease 10.0 MIF MMP9
6 bacteremia 10.0
7 meesmann corneal dystrophy 10.0 C3 MBL2
8 malignant acth producing neoplasm of pituitary gland 10.0 C3 MBL2
9 brain edema 10.0
10 endocarditis 10.0
11 uterine adnexa cancer 9.9 C3 MMP9
12 nephropathy familial with hyperuricemia 9.9 C3 MBL2
13 hyperuricemia, pulmonary hypertension, renal failure, and alkalosis 9.9 MBL2 MMP9
14 heart valve disease 9.9 C3 MIF
15 pulmonary eosinophilia 9.9 MBL2 MMP9
16 aneurysm 9.8
17 brain injury 9.8
18 vasculitis 9.8
19 thrombosis 9.8
20 quadriplegia 9.8
21 labyrinthitis 9.8
22 otitis media 9.8
23 sphenoid sinusitis 9.8
24 endotheliitis 9.8
25 common variable immunodeficiency 9.8
26 sinusitis 9.8
27 sickle cell disease 9.8
28 west nile virus 9.6
29 nasopharyngitis 9.6
30 acquired immunodeficiency syndrome 9.6
31 meningoencephalitis 9.6
32 pericarditis 9.6
33 acute disseminated encephalomyelitis 9.6
34 febrile seizures 9.6
35 c3 deficiency 9.6
36 neuritis 9.6
37 alcohol abuse 9.6
38 intracranial aneurysm 9.6
39 status epilepticus 9.6
40 peritonitis 9.6
41 arthritis 9.6
42 chlamydia 9.6
43 hepatitis c 9.6
44 herpes simplex 9.6
45 epidural abscess 9.6
46 cervicitis 9.6
47 cerebral arteritis 9.6
48 hemoglobinopathy 9.6
49 chickenpox 9.6
50 glomerulonephritis 9.6

Comorbidity relations with Pneumococcal Meningitis via Phenotypic Disease Network (PDN):


Otitis Media Respiratory Failure

Graphical network of the top 20 diseases related to Pneumococcal Meningitis:



Diseases related to Pneumococcal Meningitis

Symptoms & Phenotypes for Pneumococcal Meningitis

MGI Mouse Phenotypes related to Pneumococcal Meningitis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.35 MMP9 C3 MAPK10 MBL2 MIF
2 homeostasis/metabolism MP:0005376 9.02 MMP9 C3 MAPK10 MBL2 MIF

Drugs & Therapeutics for Pneumococcal Meningitis

Drugs for Pneumococcal Meningitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 47)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Phenytoin Approved, Vet_approved Phase 4 57-41-0 1775
2
Acetaminophen Approved Phase 4 103-90-2 1983
3
Azathioprine Approved Phase 4 446-86-6 2265
4
Cefotaxime Approved Phase 4 63527-52-6 456256 5742673
5
Cefoxitin Approved Phase 4 35607-66-0 441199
6 Sodium Channel Blockers Phase 4
7 Heptavalent Pneumococcal Conjugate Vaccine Phase 4,Phase 3,Phase 2
8 Diuretics, Potassium Sparing Phase 4
9 Vaccines Phase 4,Phase 3,Phase 2
10 Anti-Bacterial Agents Phase 4
11 Immunoglobulins Phase 4,Phase 3,Phase 2
12 Anticonvulsants Phase 4
13 Antibiotics, Antitubercular Phase 4
14 Antibodies Phase 4,Phase 3,Phase 2
15 Analgesics Phase 4
16 Analgesics, Non-Narcotic Phase 4
17 Peripheral Nervous System Agents Phase 4
18 beta-Lactams Phase 4
19 Anti-Infective Agents Phase 4
20 Immunosuppressive Agents Phase 4
21 Lactams Phase 4
22 Antimetabolites Phase 4
23 Antimetabolites, Antineoplastic Phase 4
24 Antipyretics Phase 4
25 Antirheumatic Agents Phase 4
26 Adjuvants, Immunologic Phase 4
27 Hematinics Phase 4
28 Liver Extracts Phase 4
29 BCG Vaccine Phase 4
30
Lactitol Phase 3,Phase 2 585-86-4 3871
31 Aluminum phosphate Phase 3
32
Dexamethasone Approved, Investigational, Vet_approved 50-02-2 5743
33
Azithromycin Approved 83905-01-5 55185 53477736 447043
34
Vancomycin Approved 1404-90-6 441141 14969
35 Dexamethasone acetate 1177-87-3
36 glucocorticoids
37 Gastrointestinal Agents
38 Hormone Antagonists
39 Dexamethasone 21-phosphate
40 Hormones
41 Hormones, Hormone Substitutes, and Hormone Antagonists
42 Antiemetics
43 Anti-Inflammatory Agents
44 BB 1101
45 Autonomic Agents
46 Antineoplastic Agents, Hormonal
47 Complement System Proteins

Interventional clinical trials:

(show top 50) (show all 61)
id Name Status NCT ID Phase
1 Study on the Efficacy of Phenytoin in the Prophylaxis of Seizures of Patients With Pneumococcal Meningitis at Least 50 Yrs Old. Unknown status NCT01478035 Phase 4
2 Slow Initial β-lactam Infusion With High-dose Paracetamol to Improve the Outcomes of Childhood Bacterial Meningitis Completed NCT01540838 Phase 4
3 Immunogenicity of 7-Valent Pneumococcal Conjugate Vaccine in Lung Fluid of Adults With and Without HIV Infection Completed NCT00371878 Phase 4
4 Study of Evaluating Safety and Immunogenicity of 23-Valent Pneumococcal Polysaccharide Vaccine With Influenza Vaccine in Children and Adults Completed NCT02062281 Phase 4
5 Protection Against Pneumococcal Infection in Children With T1DM Completed NCT01939522 Phase 4
6 Safety and Local Tolerability of Prevenar in Indian Children Completed NCT00488800 Phase 4
7 Immunogenicity of 3+1 Versus 2+1 Schedule for PCV7 Completed NCT02040402 Phase 4
8 Induction of Immunity Against Streptococcus Pneumoniae in Adults With Inflammatory Bowel Disease Completed NCT01908283 Phase 4
9 Pneumococcal Vaccination of Crohn Patients Completed NCT01947010 Phase 4
10 Study Evaluating the Safety and Ability to Produce Immune Response of Prevenar and Meningitec Given at the Same Time Completed NCT00581035 Phase 4
11 Persistence of Antibody Response to N. Meningitidis Group C in Children Completed NCT00316654 Phase 4
12 Immunogenicity of 13-valent Pneumococcal Conjugate Vaccine Compared to the Pneumococcal Polysaccharide Vaccine in Adult Kidney and Liver Transplant Patients Active, not recruiting NCT01781871 Phase 4
13 A Study of the Interaction Between BCG And MenC Immunisation: BAM Active, not recruiting NCT02002156 Phase 4
14 Safety and Immunogenicity of 10-valent and 13-valent Pneumococcal Conjugate Vaccines in Papua New Guinean Children Unknown status NCT01619462 Phase 3
15 An Alternative Booster Vaccine Against Meningitis and Ear Infections Completed NCT01443416 Phase 3
16 Safety and Immunogenicity Study of MenC-TT Vaccine (NeisVac-C) in Toddlers Previously Immunized With PCV7 (Prevenar®) Completed NCT00617760 Phase 3
17 Study Evaluating Safety and Immunogenicity of 13-Valent Pneumococcal Conjugate Vaccine With Influenza Vaccine in Adults Completed NCT00492557 Phase 3
18 Effect of Two Versus Three Pneumococcal Conjugate Vaccinations Completed NCT00189020 Phase 3
19 Safety and Immunogenicity of 23-valent Pneumococcal Polysaccharide Vaccine in 2 to 70 Years Old Healthy People in China Completed NCT01451086 Phase 3
20 Trial of Pneumococcal Vaccine Schedules in Ho Chi Minh City, Vietnam Completed NCT01953510 Phase 2, Phase 3
21 Comparing Two Pneumococcal Vaccines in Adults With Chronic Obstructive Pulmonary Disease Completed NCT00457977 Phase 3
22 Serological Response to Antipneumococcal Vaccination and Impact on Streptococcus Pneumoniae Nasal Carriage in HIV Adults Completed NCT02123433 Phase 3
23 Safety and Immunogenicity Evaluation After One or Two Doses of Novartis Meningococcal ACWY Conjugate Vaccine in Healthy Infants and Toddlers Completed NCT00667602 Phase 3
24 A Study to Evaluate Safety and Immune Response of Novartis Meningococcal ACWY Vaccine In Infants Completed NCT00474526 Phase 3
25 Immunogenicity and Safety of Pediatric Vaccines When Administered With Menactra® in Healthy Toddlers Completed NCT00422292 Phase 3
26 Study to Evaluate the Safety of Novartis MenACWY Conjugate Vaccine When Administered With Routine Infant Vaccinations to Healthy Infants Completed NCT00806195 Phase 3
27 Study of the Safety of Menactra® Vaccine When Administered With Other Pediatric Vaccines to Healthy Toddlers Completed NCT00483574 Phase 3
28 Safety and Immunogenicity of 2 or 3 Doses of MenACWY Conjugate Vaccine in Healthy Infants and the Effects of a Booster Dose of MenACWY Administered in the Second Year of Life Completed NCT01214837 Phase 3
29 Immunogenicity, Safety and Lot to Lot Consistency of Novartis Meningococcal B Recombinant Vaccine When Administered With Routine Infant Vaccinations to Healthy Infants Completed NCT00657709 Phase 3
30 A Phase 3B, Open Label, Multi-Center Study to Evaluate the Safety, Tolerability and Immunogenicity of Novartis Meningococcal B Recombinant Vaccine When Administered Alone to Healthy Infants According to Different Immunization Schedules and to Healthy Chil Completed NCT01339923 Phase 3
31 A Study of 2 Doses of Menactra®, a Meningococcal Conjugate Vaccine in Healthy Toddlers Completed NCT00384397 Phase 3
32 A Study to Compare the Immunogenicity of GSK Biologicals' 10Pn-PD-DiT 4-dose Presentation to the Licensed 1-dose Synflorix™ (10Pn-PD-DiT) Vaccine When Co-administered With DTPw-combination Vaccine in Healthy Infants Completed NCT02447432 Phase 3
33 Reduced PCV Dosing Schedules in South African Infants Recruiting NCT02943902 Phase 3
34 Pneumococci and Hib Vaccination After Neurotrauma or Neurosurgery Completed NCT02806284 Phase 2
35 Neonatal Immunization With Pneumococcal Conjugate Vaccine in Papua New Guinea Completed NCT00219401 Phase 2
36 Pneumococcal Vaccination of Fiji Infants Completed NCT00170612 Phase 2
37 Study to Evaluate the Response Rate to the Licensed Pneumovax 23™ in Elderly Population. Completed NCT00307008 Phase 2
38 Prospective Trial of Vaccine Responses Against Pneumococcus and Influenza in Adult Cancer Patients 65 Years of Age and Older Completed NCT00741039 Phase 2
39 Immunogenicity and Safety of MenACWY in Infants (6 & 12 Months) Completed NCT00310856 Phase 2
40 Regulation of Mucosal Immune Response to Systemic MenB Vaccine Completed NCT00774384 Phase 2
41 Immunogenicity Study of an Anti-pneumococcal Vaccination Strategy in Patients With Sickle Cells Disease Recruiting NCT02274415 Phase 2
42 Penetration of Ceftaroline Into Cerebrospinal Fluid(CSF) Recruiting NCT02806882 Phase 1
43 Lebanese Interhospital Pneumococcal Surveillance Program Unknown status NCT00901602
44 Identification and Quantification of Immune Response Induced by Hyaluronidase and Other Factors of Virulence of Invasive Human Infections of Streptococcus Pneumoniae Unknown status NCT01931800
45 Vancomycin Concentration in Cerebrospinal Fluid During Pneumococcal Meningitis Completed NCT00162578
46 Study Evaluating Pneumococcal Meningitis in the Paediatric Population in Spain Four Years After the Marketing of Prevenar. Completed NCT00227214
47 Child Pneumococcal Serotype Epidemiology In Greece Completed NCT01111214
48 Disease Burden of Pneumonia, Meningitis and Bacteremia Among Children in Japan: Pneumonet Japan Completed NCT00757575
49 Understanding Pneumococcal Carriage and Disease Completed NCT01996007
50 Neisseria Meningitidis Burden of Disease Study Completed NCT01730391

Search NIH Clinical Center for Pneumococcal Meningitis

Genetic Tests for Pneumococcal Meningitis

Anatomical Context for Pneumococcal Meningitis

MalaCards organs/tissues related to Pneumococcal Meningitis:

39
Brain, Testes, Neutrophil, Bone, Cortex, Endothelial, Spinal Cord

Publications for Pneumococcal Meningitis

Articles related to Pneumococcal Meningitis:

(show top 50) (show all 584)
id Title Authors Year
1
The Early Adaptive Immune Response in the Pathophysiological Process of Pneumococcal Meningitis. ( 27803171 )
2017
2
Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis. ( 28086930 )
2017
3
Pneumococcal meningitis outbreaks in sub-Saharan Africa. ( 27305709 )
2016
4
Surgically Cured, Relapsed Pneumococcal Meningitis Due to Bone Defects, Non-invasively Identified by Three-dimensional Multi-detector Computed Tomography. ( 27980270 )
2016
5
Diarrhea-associated pneumococcal meningitis with complicating hydrocephalus in a child in a resource-limited setting. ( 27580337 )
2016
6
Depression-Like Adult Behaviors may be a Long-Term Result of Experimental Pneumococcal Meningitis in Wistar Rats Infants. ( 27364961 )
2016
7
Impact of pneumococcal conjugate vaccines on pneumococcal meningitis cases in France between 2001 and 2014: a time series analysis. ( 27998266 )
2016
8
Predictive risk factors for Listeria monocytogenes meningitis compared to pneumococcal meningitis: a multicenter case-control study. ( 27541039 )
2016
9
Exome Array Analysis of Susceptibility to Pneumococcal Meningitis. ( 27389768 )
2016
10
Pneumococcal meningitis: clinical-pathological correlations (MeninGene-Path). ( 27001057 )
2016
11
An outbreak of pneumococcal meningitis among older children (a8Y5A years) and adults after the implementation of an infant vaccination programme with the 13-valent pneumococcal conjugate vaccine in Ghana. ( 27756235 )
2016
12
Genetic Variation in NFKBIE Is Associated With Increased Risk of Pneumococcal Meningitis in Children. ( 26870821 )
2016
13
Cerebrovascular Complications of Pediatric Pneumococcal Meningitis in the PCV13 Era. ( 27247340 )
2016
14
Refractory status epilepticus due to pneumococcal meningitis in an infant with congenital immunodeficiency. ( 27606021 )
2016
15
Infection of zebrafish embryos with live fluorescent Streptococcus pneumoniae as a real-time pneumococcal meningitis model. ( 27542968 )
2016
16
Edaravone attenuates hippocampal damage in an infant mouse model of pneumococcal meningitis by reducing HMGB1 and iNOS expression via the Nrf2/HO-1 pathway. ( 27569388 )
2016
17
Sex-based differences in pneumococcal serotype distribution in adults with pneumococcal meningitis. ( 27567977 )
2016
18
Dramatic reduction of mortality in pneumococcal meningitis. ( 27716447 )
2016
19
Pneumococcal Meningitis in the PCV13 Era: A Cluster of Cases With Increased Morbidity and Mortality. ( 26902305 )
2016
20
Variation of 46 Innate Immune Genes Evaluated for their Contribution in Pneumococcal Meningitis Susceptibility and Outcome. ( 27432718 )
2016
21
The Severity of Infection Determines the Localization of Damage and Extent of Sensorineural Hearing Loss in Experimental Pneumococcal Meningitis. ( 27445150 )
2016
22
Streptococcus pneumoniae capsule determines disease severity in experimental pneumococcal meningitis. ( 27009189 )
2016
23
Therapeutic hypothermia and inhalation anesthesia in a patient with severe pneumococcal meningitis and secondary cardiac arrest. ( 27856137 )
2016
24
Functional polymorphisms of macrophage migration inhibitory factor as predictors of morbidity and mortality of pneumococcal meningitis. ( 26976591 )
2016
25
V-akt murine thymoma viral oncogene homolog 3 (AKT3) contributes to poor disease outcome in humans and mice with pneumococcal meningitis. ( 27193124 )
2016
26
The wider implications of normal cerebrospinal fluid cellularity in pneumococcal meningitis. ( 26776534 )
2016
27
Abdominal aortitis and aneurysm impending rupture during pneumococcal meningitis. ( 27477988 )
2016
28
Comparative impact of pneumococcal conjugate vaccines on pneumococcal meningitis according to underlying conditions. ( 27595445 )
2016
29
Thioredoxins and Methionine Sulfoxide Reductases in the Pathophysiology of Pneumococcal Meningitis. ( 27368348 )
2016
30
Comparison of the clinical presentations of Naegleria fowleri primary amoebic meningoencephalitis with pneumococcal meningitis: a case-control study. ( 26922583 )
2016
31
Pneumococcal meningitis is promoted by single cocci expressing pilus adhesin RrgA. ( 27348589 )
2016
32
Do Innate Immune Gene Variations Contribute to Susceptibility and Severity of Pneumococcal Meningitis? ( 27478066 )
2016
33
Inhibition of Hippocampal Regeneration by Adjuvant Dexamethasone in Experimental Infant Rat Pneumococcal Meningitis. ( 26824948 )
2016
34
Antibody-induced neutrophil depletion prior to the onset of pneumococcal meningitis influences long-term neurological complications in mice. ( 26965652 )
2016
35
Autosplenectomy Causing Catastrophic Pneumococcal Meningitis in a Patient with Lupus/Antiphospholipid Antibody Syndrome. ( 26882790 )
2016
36
Clinical, biochemical and microbiological factors associated with the prognosis of pneumococcal meningitis in children. ( 25998267 )
2015
37
CCAAT/enhancer-binding protein I' (C/EBPI') aggravates inflammation and bacterial dissemination during pneumococcal meningitis. ( 25958220 )
2015
38
Effect of dexamethasone on the efficacy of daptomycin in the therapy of experimental pneumococcal meningitis. ( 25813395 )
2015
39
Adjuvant treatment with dexamethasone plus anti-C5 antibodies improves outcome of experimental pneumococcal meningitis: a randomized controlled trial. ( 26272468 )
2015
40
Chiasmal optic neuritis may be secondary to pneumococcal meningitis: a child with acute monocular vision loss. ( 26343036 )
2015
41
Effect of the 13-Valent Pneumococcal Conjugate Vaccine on Pneumococcal Meningitis in Children. ( 26265497 )
2015
42
Type 19 Pneumococcal Meningitis: A Patient With 75-Year Clinical and Serologic Follow Up, With a Review of the Evolution of Therapy From Antiserum to Sulfonamides to Penicillin. ( 26501468 )
2015
43
Sphenoid Sinusitis Complicated by Pneumococcal Meningitis and an Infectious Aneurysm in the Intracavernous Carotid Artery. ( 26179539 )
2015
44
Experimental study of cerebrospinal fluid tumor necrosis factor-alpha release in penicillin- and cephalosporin-resistant pneumococcal meningitis treated with different antibiotic schedules. ( 26452467 )
2015
45
Pneumococcal Meningitis and Endocarditis: a Case Report. ( 26561418 )
2015
46
Establishment of rat pneumococcal meningitis models: a histopathological analysis. ( 25973135 )
2015
47
Severe Sepsis due to Otogenic Pneumococcal Meningitis with Pneumocephalus without Meningeal Symptoms. ( 26134202 )
2015
48
Pneumococcal meningitis and vaccine effects in the era of conjugate vaccination: results of 20 years of nationwide surveillance in Germany. ( 25885764 )
2015
49
Pneumococcal meningitis-associated pyogenic ventriculitis. ( 25452044 )
2015
50
The matrix metalloproteinase inhibitor RS-130830 attenuates brain injury in experimental pneumococcal meningitis. ( 25890041 )
2015

Variations for Pneumococcal Meningitis

Expression for Pneumococcal Meningitis

Search GEO for disease gene expression data for Pneumococcal Meningitis.

Pathways for Pneumococcal Meningitis

Pathways related to Pneumococcal Meningitis according to GeneCards Suite gene sharing:

(show all 13)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.31 C3 MAPK10 MBL2 MIF MMP9
2 11.71 C3 MBL2
3
Show member pathways
11.7 C3 MAPK10 MBL2 MMP9
4
Show member pathways
11.67 C3 MBL2
5 11.64 C3 MBL2
6 11.62 MAPK10 MMP9
7
Show member pathways
11.58 C3 MBL2
8 11.51 MIF MMP9
9 11.44 MAPK10 MMP9
10
Show member pathways
11.39 C3 MBL2
11 11.14 C3 MAPK10
12
Show member pathways
10.96 MIF MMP9
13 10.7 C3 MBL2

GO Terms for Pneumococcal Meningitis

Cellular components related to Pneumococcal Meningitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.56 C3 MBL2 MIF MMP9
2 ficolin-1-rich granule lumen GO:1904813 9.16 MIF MMP9
3 secretory granule lumen GO:0034774 8.96 C3 MIF
4 extracellular space GO:0005615 8.92 C3 MBL2 MIF MMP9

Biological processes related to Pneumococcal Meningitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 proteolysis GO:0006508 9.58 C3 MBL2 MMP9
2 innate immune response GO:0045087 9.5 C3 MBL2 MIF
3 complement activation, classical pathway GO:0006958 9.43 C3 MBL2
4 neutrophil degranulation GO:0043312 9.43 C3 MIF MMP9
5 complement activation GO:0006956 9.37 C3 MBL2
6 immune system process GO:0002376 9.33 C3 MBL2 MIF
7 positive regulation of phagocytosis GO:0050766 8.96 C3 MBL2
8 positive regulation of protein phosphorylation GO:0001934 8.8 C3 MIF MMP9

Molecular functions related to Pneumococcal Meningitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 receptor binding GO:0005102 9.13 C3 MBL2 MIF
2 serine-type endopeptidase activity GO:0004252 8.8 C3 MBL2 MMP9

Sources for Pneumococcal Meningitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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