MCID: PNM006
MIFTS: 55

Pneumoconiosis malady

Category: Respiratory diseases

Aliases & Classifications for Pneumoconiosis

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Aliases & Descriptions for Pneumoconiosis:

Name: Pneumoconiosis 10 47 12 36 65

Classifications:



External Ids:

Disease Ontology10 DOID:10316
ICD1027 J64
ICD9CM29 505
MeSH36 D011009
NCIt42 C26861
UMLS65 C0032273

Summaries for Pneumoconiosis

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Wikipedia:68 Pneumoconiosis is an occupational lung disease and a restrictive lung disease caused by the inhalation... more...

MalaCards based summary: Pneumoconiosis is related to baritosis and pulmonary hypertension. An important gene associated with Pneumoconiosis is CAT (Catalase), and among its related pathways are IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types and LDL Oxidation in Atherogenesis. Affiliated tissues include lung, liver and heart, and related mouse phenotypes are respiratory system and reproductive system.

Disease Ontology:10 An interstitial lung disease that is caused by the inhalation of dust.

Related Diseases for Pneumoconiosis

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Diseases in the Pneumoconiosis family:

Pneumoconiosis Due to Talc

Diseases related to Pneumoconiosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 233)
idRelated DiseaseScoreTop Affiliating Genes
1baritosis31.5CAT, GSTM1, IL6
2pulmonary hypertension30.4CCL2, SOD1, TGFB1
3skin disease30.3IL1A, TNF
4mycobacterium malmoense29.8FN1, NLRP3
5pulmonary sarcoidosis29.5CCL2, IL1B, MUC5B, TGFB1
6rheumatoid arthritis27.6CAT, CCL2, CXCL8, IL1A, IL1B, IL6
7mixed mineral dust pneumoconiosis25.7CAT, CCL2, CP, CXCL8, FAS, FASLG
8pneumoconiosis due to talc12.1
9graphite pneumoconiosis12.1
10kaolin pneumoconiosis12.0
11slate pneumoconiosis11.9
12silicosis11.8
13anthracosis11.8
14caplan's syndrome11.5
15labrador lung11.3
16silicosiderosis11.2
17asbestosis11.0
18polycythemia10.9IL1B, TNF
19berylliosis10.8
20mini stroke10.8CAT, SOD1
21stargardt macular degeneration absent or hypoplastic corpus callosum mental retardation and dysmorphic features10.8IL1B, TNF
22burns10.7FAS, TGFB1
23peyronie's disease10.7IL1B, TNF
24intermediate dend syndrome10.7IL6, TNF
25developmental and speech delay due to sox5 deficiency10.6FAS, FASLG, TNF
26residual stage angle-closure glaucoma10.6IL1B, IL6, TNF
27refractory plasma cell neoplasm10.6IL1B, IL6, TNF
28skin conditions10.6IL1B, IL6, TNF
29retinal vein occlusion10.6CAT, SOD1, TNF
30postsurgical hypothyroidism10.6IL1B, IL6, TNF
31rubeosis iridis10.6IL1B, IL6, TNF
32ureteral disease10.6IL1B, IL6, TNF
33duodenum cancer10.6IL1B, IL6, TNF
34testicular granulosa cell tumor10.6CXCL8, IL1B, TNF
35dancing eyes-dancing feet syndrome10.6FAS, IL6, TNF
36dentin caries10.6IL1B, IL6, TNF
37reflex sympathetic dystrophy10.6IL1B, TGFB1, TNF
38placental abruption10.6IL1B, IL6, TNF
39meige syndrome10.6IL1B, IL6, TNF
40tracheal stenosis10.6IL1B, IL6, TNF
41skeletal tuberculosis10.6FAS, FASLG, IL1B
42chronic monocytic leukemia10.6IL1B, IL6, SOD1
43crohn's disease10.6IL6, TNF
44posterior valve urethra10.6IL6, TGFB1, TNF
45anatomical narrow angle borderline glaucoma10.6IL1A, IL1B
46best1 retinopathy10.6TGFB1, TNF
47peritoneal mesothelioma10.6IL1B, IL6, TNF
48cystic echinococcosis10.6IL1B, IL6, TGFB1
49odontoclasia10.6IL1B, IL6, TNF
50pediatric infratentorial ependymoma10.6CXCL8, IL1B, TNF

Comorbidity relations with Pneumoconiosis via Phenotypic Disease Network (PDN):


Coronary Artery DiseaseIschemic Heart Disease
Familial Atrial FibrillationAnthracosis
Prostatic HypertrophyRespiratory Failure
Heart DiseasePostinflammatory Pulmonary Fibrosis
Bronchitis

Graphical network of the top 20 diseases related to Pneumoconiosis:



Diseases related to pneumoconiosis

Symptoms for Pneumoconiosis

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Drugs & Therapeutics for Pneumoconiosis

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Drugs for Pneumoconiosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 33)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
IronapprovedPhase 410217439-89-623925
Synonyms:
02583_FLUKA
12310_ALDRICH
12310_RIEDEL
129048-51-7
14067-02-8
161135-39-3
190454-13-8
195161-83-2
199281-22-6
209309_ALDRICH
209309_SIAL
255637_ALDRICH
266213_ALDRICH
266256_ALDRICH
267945_ALDRICH
267953_ALDRICH
26Fe
338141_ALDRICH
356808_ALDRICH
356824_ALDRICH
356832_ALDRICH
39344-71-3
3ZhP
413054_ALDRICH
443783-52-6
44890_ALDRICH
44890_FLUKA
675141-17-0
70884-35-4
73135-38-3
7439-89-6
8011-79-8
8053-60-9
AC1L2N38
ATW 230
ATW 432
Ancor B
Ancor en 80/150
Armco iron
Atomel 28
Atomel 300M200
Atomel 500M
Atomel 95
Atomiron 44MR
Atomiron 5M
Atomiron AFP 25
Atomiron AFP 5
C00023
C3518_SIAL
C3518_SIGMA
CCRIS 1580
CHEBI:18248
CID23925
Carbonyl iron
Copy Powder CS 105-175
D007501
DB01592
DSP 1000
DSP 128B
DSP 135
DSP 135C
DSP 138
Dexiron
Diseases (animal), iron overload
Diseases, iron overload
EF 1000
EF 250
EFV 200/300
EFV 250
EFV 250/400
EINECS 231-096-4
Ed-In-Sol
 
Eisen
F 60 (metal)
FE
FT 3 (element)
Fe
Fe-40
Fe1+
Feraheme
Feronate
Ferretts
Ferrlecit
Ferro-Caps
Ferro-Time
Ferrousal
Ferrovac E
Ferrum
GS 6
HF 2 (element)
HL (iron)
HQ (metal)
HS (iron)
HS 4849
HSDB 604
Hemocyte
Hierro
Hoeganaes ATW 230
Hoeganaes EH
IRMM524A_FLUKA
IRMM524B_FLUKA
IRON
Infufer
Iron
Iron (Fe)
Iron (Fe1+)
Iron ion (Fe+)
Iron ion(1+)
Iron monocation
Iron standard for AAS
Iron(1+)
Iron(1+) ion
Iron(III) nitrate solution
Iron, elemental
Iron, ion (Fe1+)
Iron, ion (Fe1+) (8CI,9CI)
LOHA
LS-3196
MolPort-003-925-001
NC 100
PZh-1M3
PZh-2
PZh1M1
PZh2M
PZh2M1
PZh2M2
PZh3
PZh3M
PZh4M
PZhO
Remko
SUY-B 2
Siderol
UNII-E1UOL152H7
Venofer
Vitedyn-Slo
Yieronia
fer
ferrous ascorbate
ferrous fumarate
ferrous gluconate
ferrous glycine sulfate
ferrous iron
ferrous succinate
ferrous sulfate
hierro
2
DeferiproneapprovedPhase 45330652-11-02972
Synonyms:
1,2-Dimethyl-3-hydroxypyrid-4-one
3-Hydroxy-1,2-dimethyl-4(1H)-pyridone
APO-066
CP-20
DN-180-01-AF
Deferipron
 
Deferiprona
Deferiproni
Deferipronum
Deferypron
Dimethylhydroxypyridone
Défériprone
Ferriprox
PL-1
3Iron Chelating AgentsPhase 4178
4Chelating AgentsPhase 4667
5
AmlodipineapprovedPhase 2, Phase 344988150-42-92162
Synonyms:
()-Amlodipine
(RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridine
2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)
3,5-Pyridinedicarboxylic acid, 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-Ethyl-5-methyl ( -)-2-((2-aminoethoxy)methyl)-4-(2-chlorphenyl)-1,4-dihydro-6-methyl-3,5-pyridindicarboxylat
3-Ethyl-5-methyl ( -)-2-((2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-Ethyl-5-methyl (+-)-2-(2-aminoethoxymethyl)-4-(O-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-Ethyl-5-methyl (+-)-2-(2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-Ethyl-5-methyl (.+/-.)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
3-ethyl 5-methyl 2-{[(2-aminoethyl)oxy]methyl}-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
88150-42-9
88150-47-4 (maleate (1:1))
AC-4535
AC1L1D26
AC1Q32ZS
AMLODIPINE BASE
AMVAZ
Ambap88150-42-9
Amlocard
Amlodipine
Amlodipine (INN)
Amlodipine Benzenesulfonate
Amlodipine Besilate
Amlodipine Besylate
Amlodipine Free Base
Amlodipine Maleate
Amlodipine [INN:BAN]
Amlodipine besilate
Amlodipine besylate
Amlodipine free base
Amlodipino
Amlodipino [Spanish]
Amlodipinum
Amlodipinum [Latin]
Amlodis
Amlopres
Amlor
 
Amvaz
BIDD:GT0810
BRD-A22032524-074-02-4
BRD-A22032524-074-03-2
BSPBio_002727
C06825
CHEBI:2668
CHEMBL1491
CID2162
CPD000469198
Coroval
D07450
DB00381
HMS2052N03
HMS2089H07
I14-0798
Intervask
Istin
KBio3_001947
KBioGR_001643
LS-131183
Lipinox
Lotrel
MLS001401409
MolPort-001-792-963
NCGC00165957-01
NCGC00165957-02
NCGC00165957-03
Norvasc
Norvasc (TN)
Pelmec
R,S)-Amlodipine
Racemic Amlodipine
SAM001246705
SMR000469198
SPBio_000351
Spectrum2_000486
Spectrum3_001004
Spectrum4_001132
Spectrum5_001550
UK-4834011
UNII-1J444QC288
amlodipine
6
Metoprololapproved, investigationalPhase 2, Phase 319337350-58-64171
Synonyms:
(+/-)-Metoprolol
(RS)-Metoprolol
1-(Isopropylamino)-3-(4-(2-methoxyethyl)phenoxy)propan-2-ol
1-(Isopropylamino)-3-(p-(2-methoxyethyl)phenoxy)-2-propanol
1-(isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-ol
1-[(1-methylethyl)amino]-3-({4-[2-(methyloxy)ethyl]phenyl}oxy)propan-2-ol
1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol
1-[4-(2-methoxyethyl)phenoxy]-3-propan-2-ylamino-propan-2-ol
3-[4-(2-methoxyethyl)phenoxy]-1-(propan-2-ylamino)propan-2-ol
37350-58-6
51384-51-1
54163-88-1
AB00053499
AC-19022
AC1L1HKM
AstraZeneca Brand of Metaoprolol Tartrate
AstraZeneca Brand of Seloken
BRD-A03623303-045-02-0
Beatrolol
Beloc
Beloc Duriles
Beloc-Duriles
BelocDuriles
Betaloc
Betaloc Astra
Betaloc-Astra
BetalocAstra
Betalok
C07202
CCRIS 4198
CGP 2175
CGP-2175
CGP2175
CHEBI:6904
CHEMBL13
CID4171
D008790
D02358
DB00264
Dl-Metoprolol
Dutoprol
EINECS 253-483-7
EINECS 257-166-4
H 93 26
H 93-26
H 9326
HMS2090B15
 
HSDB 6531
I01-7125
I06-0125
Jsp006606
L000669
LOPRESSIDONE
LS-122450
Leiras Brand of Metoprolol Succinate or Metoprolol Tartrate
Lopresor
Lopresoretic
Lopressor
Lopressor HCT
Meijoprolol
Metohexal
Metoprolol
Metoprolol (USAN/INN)
Metoprolol Succinate
Metoprolol Succinate extended-release
Metoprolol Tartrate
Metoprolol [USAN:INN:BAN]
Metoprolol succinate
Metoprolol tartrate
Metoprololum
Metoprololum [INN-Latin]
Metroprolol
MolPort-005-938-039
NCGC00021148-02
NCGC00021148-03
NCGC00021148-04
Novartis Brand of Metprolol Tartrate
Preblok
Prelis
Presolol
Selo-Zok
Seloken
Seloken AstraZeneca Brand
Selopral
Seroken
Spesicor
Spesikor
TOPROL-XL
Tartrate, Metoprolol
Toprol
Toprol XL
Toprol-XL
UNII-GEB06NHM23
dl-Metoprolol
metoprolol
7Peripheral Nervous System AgentsPhase 2, Phase 3, Phase 118510
8Calcium, DietaryPhase 2, Phase 34678
9Neurotransmitter AgentsPhase 2, Phase 314795
10calcium channel blockersPhase 2, Phase 31743
11Vasodilator AgentsPhase 2, Phase 32926
12Antihypertensive AgentsPhase 2, Phase 33618
13Adrenergic AgentsPhase 2, Phase 34204
14Adrenergic beta-1 Receptor AntagonistsPhase 2, Phase 3292
15Adrenergic AntagonistsPhase 2, Phase 31253
16Anti-Arrhythmia AgentsPhase 2, Phase 32371
17Adrenergic beta-AntagonistsPhase 2, Phase 3979
18
InfliximabapprovedPhase 1, Phase 2349170277-31-3
Synonyms:
Ig gamma-1 chain C region
 
Inflectra
Remicade
Remsima
19Antirheumatic AgentsPhase 1, Phase 28496
20Contraceptives, OralPhase 1, Phase 23734
21MesalaminePhase 1, Phase 215289-57-6
22Anti-Inflammatory Agents, Non-SteroidalPhase 1, Phase 23549
23Anti-Inflammatory AgentsPhase 1, Phase 28478
24AnalgesicsPhase 1, Phase 29358
25MitogensPhase 1, Phase 21386
26Analgesics, Non-NarcoticPhase 1, Phase 25184
27Dermatologic AgentsPhase 1, Phase 24555
28Gastrointestinal AgentsPhase 1, Phase 26401
29
Heparinapproved, investigational7199005-49-6772, 46507594
Synonyms:
101921-26-0
102-94-3
102785-31-9
104521-37-1
11078-24-3
11129-39-8
12656-11-0
2-o-sulfohexopyranuronosyl-(1->4)-2-deoxy-3-o-sulfo-2-(sulfoamino)hexopyranosyl-(1->4)-2-o-sulfohexopyranuronosyl-(1->4)-2-acetamido-2-deoxy-6-o-sulfohexopyranose
37324-73-5
6-[6-[6-[5-acetamido-4,6-dihydroxy-2-(sulfooxymethyl)oxan-3-yl]oxy-2-carboxy-4-hydroxy-5-sulfooxyoxan-3-yl]oxy-2-(hydroxymethyl)-5-(sulfoamino)-4-sulfooxyoxan-3-yl]oxy-3,4-dihydroxy-5-sulfooxyoxane-2-carboxylic acid
9041-08-1
9045-22-1
9075-96-1
913079-23-9
91449-79-5
AC1L19ZN
AC1L1ROY
ALFA 87-120
ALFA 87-163
ALFA 87-198
ALFA 87-81
ALFA 88-247
AR-1E4539
Allocinnamic acid
Ardeparin
Ardeparin sodium
Arteven
Bemiparin
Bemiparin sodium
CID772
CID8784
CY 216
Calciparine
Certoparin
Clexane
Clivarin
Clivarine
Cy 222
D006495
D017984
DB00407
DB01225
Dalteparin
Dalteparin sodium
Depo-Heparin
EINECS 232-681-7
EMT 966
EMT 967
EMT-966
EMT-967
EMT966
EMT967
Enoxaparin
Enoxaparin sodium
Enoxaparine
Eparina
Eparina [DCIT]
FR 860
Fluxum
Fragmin A
Fragmin B
Fragmin IV
Fraxiparin
H 2149
HSDB 3094
Hed-heparin
Hep Flush Kit in plastic container
Hep-Lock
Hep-Lock U/P
Hep-lock
Heparin
Heparin CY 216
Heparin Lock Flush
Heparin Lock Flush in plastic container
Heparin Lock Flush preservative free
Heparin Lock Flush preservative free in plastic container
Heparin Sodium
Heparin natrium
Heparin sodium
Heparin sodium 1,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 1,000 units in dextrose 5% in plastic container
Heparin sodium 1,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 10,000 units in dextrose 5%
Heparin sodium 10,000 units in dextrose 5% in plastic container
Heparin sodium 10,000 units in sodium chloride 0.45%
Heparin sodium 10,000 units in sodium chloride 0.9%
Heparin sodium 12,500 units in dextrose 5%
Heparin sodium 12,500 units in dextrose 5% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.45% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.9%
Heparin sodium 2,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 2,000 units in dextrose 5% in plastic container
Heparin sodium 2,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 20,000 units and dextrose 5% in plastic container
Heparin sodium 20,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units and dextrose 5% in plastic container
 
Heparin sodium 25,000 units in dextrose 5%
Heparin sodium 25,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.45% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.9%
Heparin sodium 25,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units in dextrose 5% in plastic container
Heparin sodium 5,000 units in sodium chloride 0.45%
Heparin sodium 5,000 units in sodium chloride 0.9%
Heparin sodium 5,000 units in sodium chloride 0.9% in plastic container
Heparin sodium in plastic container
Heparin sodium preservative Free
Heparin sulfate
Heparin sulphate
Heparin, Low Molecular Weight
Heparin, Low-Molecular-Weight
Heparin, sodium salt
Heparina
Heparina [INN-Spanish]
Heparinate
Heparine
Heparine [INN-French]
Heparinic acid
Heparinsodiumsalt
Heparinum
Heparinum [INN-Latin]
Heparinum natricum
Hepathrom
Hepflush-10
Inno-Hep
Innohep
Isocinnamic acid
KB 101
Kabi 2165
LHN 1
LMWH
Lioton 1000
Lipo-hepin
Liquaemin
Liquaemin Lock Flush
Liquaemin Sodium
Liquaemin sodium preservative free
Liquemin
Logiparin
Lovenox
Lovenox HP
Low Molecular Weight Heparin
Low molecular weight heparin
Low molecular weight heparin sodium
Low-Molecular-Weight Heparin
Minolteparin sodium
MolPort-003-760-257
Multiparin
NSC174025
Nadroparin
Nadroparine
Novoheparin
OP 386
OP 622
Octaparin
PK 10,169
PK-10,169
PK-10169
PK10,169
PK10169
Pabyrin
Panheprin
Parnaparin
Parnaparin sodium
Parvoparin
Pularin
Reviparin
Reviparin sodium
Ro 11
Sandoparin
Sodium acid heparin
Sodium heparin
Sodium heparinate
Subeparin
Sublingula
Thromboliquine
Tinzaparin
Tinzaparin sodium
Triofiban
UNII-12M44VTJ7B
UNII-3S182ET3UA
UNII-E47C0NF7LV
UNII-T2410KM04A
UNII-ZZ45AB24CA
Vetren
Vitrum AB
WY 90493RD
alpha-Heparin
cis-.beta.-Carboxystyrene
cis-Cinnamic acid
enoxaparin
heparin
30Respiratory System Agents3931
31calcium heparin719
32Pharmaceutical Solutions7004
33XenonPhase 059

Interventional clinical trials:

(show all 20)
idNameStatusNCT IDPhase
1Observational Study of Deferiprone (Ferriprox®) in the Treatment of Superficial SiderosisActive, not recruitingNCT01284127Phase 4
2Effects of Metroprolol and Amlodipine on Blood Pressure Variation in Hypertensive Sleep Apnea SyndromeRecruitingNCT02408172Phase 2, Phase 3
3Safety Study of Autologous Bone Marrow Stromal Cells With Modification by Hepatocyte Growth Factor to Treat SilicosisCompletedNCT01977131Phase 1, Phase 2
4Targeting Oxidative Stress in Chronic Beryllium DiseaseCompletedNCT01088243Phase 1, Phase 2
5Beryllium Infliximab Study: Clinical Interventional TrialTerminatedNCT00111917Phase 1, Phase 2
6Safety of Stem Cells Intrabronchial Instillation for SilicosisCompletedNCT01239862Phase 1
7A Study on Pneumoconiosis Treated With Whole-lung Lavage Combined With Mesenchymal Stem CellsRecruitingNCT02668068Phase 1
8Specialized Center of Research in Occupational and Immunologic Lung DiseaseCompletedNCT00005280
9Oscillation Mechanics of the Respiratory System in Never-smoking Patients With SilicosisCompletedNCT01725971
10fMRI of the Brainstem in Migraine Sufferers and Controls. Does Iron Deposition Correlate With Progression of Disease?CompletedNCT00868556
11Identifying Shared Genetic Susceptibility Regions in Chronic Beryllium Disease and SarcoidosisCompletedNCT00560989
12Exposure in Epigenetic Regulation of Immune Response in Chronic Beryllium Disease (CBD)RecruitingNCT02604693
13The Role of JAK2 in Alveolar Macrophages (AM's) in Chronic Beryllium Disease (CBD)RecruitingNCT02596347
14Evaluation of Myocardial Iron Deposition in Patients of Heart Failure Using T2* MR ImagingRecruitingNCT02527330
15Oscillation Mechanics of the Respiratory System Asbestos Exposed: Early DiagnosisRecruitingNCT02280343
16Superficial Siderosis in Patients With Suspected Cerebral Amyloid AngiopathyRecruitingNCT01856699
17Assessment of Iron Deposition in Major Organs of Hemodialysis PatientsRecruitingNCT01169961
18Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung DisordersNot yet recruitingNCT02748798Phase 0
19Oxidative Stress Biomarkers to Monitor and Early Detect Health Impairment in Workers Exposed to Silica (Caesar Stone)Not yet recruitingNCT01338064
20DNA-damage Pathways in Workers Exposed to Silica (Caesar Stone)Not yet recruitingNCT01329003

Search NIH Clinical Center for Pneumoconiosis


Cochrane evidence based reviews: pneumoconiosis

Genetic Tests for Pneumoconiosis

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Anatomical Context for Pneumoconiosis

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MalaCards organs/tissues related to Pneumoconiosis:

33
Lung, Liver, Heart, Thyroid, Skin, Brain, Breast

Animal Models for Pneumoconiosis or affiliated genes

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MGI Mouse Phenotypes related to Pneumoconiosis:

38 (show all 14)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.3FAS, FASLG, IL6, MUC5B, SCGB1A1, TGFB1
2MP:00053898.1FAS, FASLG, FN1, IL6, NLRP3, SOD1
3MP:00053707.9CP, FAS, FASLG, FN1, IL6, NLRP3
4MP:00036317.5CP, FAS, FASLG, FN1, IL1B, IL6
5MP:00053907.4FAS, FASLG, FN1, IL1B, IL6, NLRP3
6MP:00053847.2CAT, CP, FAS, FASLG, FN1, IL6
7MP:00107717.0FAS, FASLG, FN1, IL1A, IL1B, IL6
8MP:00053856.9CP, FAS, FASLG, FN1, IL1A, IL1B
9MP:00020066.6CAT, FAS, FASLG, FN1, IL1A, IL1B
10MP:00107686.4CAT, FAS, FASLG, FN1, IL1B, IL6
11MP:00053976.0CP, FAS, FASLG, FN1, IL1A, IL1B
12MP:00053765.4CAT, CP, FAS, FASLG, FN1, IL1A
13MP:00053875.1CCL2, CP, FAS, FASLG, FN1, IL1A

Publications for Pneumoconiosis

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Articles related to Pneumoconiosis:

(show top 50)    (show all 597)
idTitleAuthorsYear
1
Lung transplantation is increasingly common among patients with coal workers' pneumoconiosis. (26725917)
2016
2
Pneumoconiosis Redux. Coal Workers' Pneumoconiosis and Silicosis Are Still a Problem. (26977968)
2016
3
Patterns of pneumoconiosis mortality in Kentucky: Analysis of death certificate data. (26374490)
2015
4
Prevalence of pneumoconiosis in Hubei, China from 2008 to 2013. (25158135)
2014
5
Comparison of High-resolution Computerized Tomography with Film-screen Radiography for the Evaluation of Opacity and the Recognition of Coal Workers' Pneumoconiosis. (24953093)
2014
6
Small mine size is associated with lung function abnormality and pneumoconiosis among underground coal miners in Kentucky, Virginia and West Virginia. (25052085)
2014
7
Mixed pneumoconiosis due to silicates and hard metals associated with primary SjAPgren's syndrome due to silica. (24626278)
2014
8
Associations between tumor necrosis factor alpha gene -238 G/A and -308 G/A polymorphisms and the risk of pneumoconiosis: update of a meta-analysis. (23919499)
2013
9
Mixed dust pneumoconiosis occurring in an unusual setting. (24296771)
2013
10
Interleukin gene polymorphisms in pneumoconiosis. (22580886)
2012
11
Miners compensated for pneumoconiosis and glutathione s-transferases M1 and T1 genotypes. (22686319)
2012
12
Functional state of RBC and neutrophils in pneumoconiosis patients variable in tolerance to dust factor in after contact period]. (22242279)
2011
13
Denim sandblasters' pneumoconiosis. (21466064)
2011
14
Rheumatoid pneumoconiosis (Caplan's syndrome). (20493416)
2010
15
What component of coal causes coal workers' pneumoconiosis? (19333134)
2009
16
Coal workers' pneumoconiosis-related years of potential life lost before age 65 years - United States, 1968-2006. (20032926)
2009
17
Airway function and respiratory resistance in Taiwanese coal workers with simple pneumoconiosis. (19664351)
2009
18
Cytogenetic monitoring of coal workers and patients with coal workers' pneumoconiosis in Turkey. (18288720)
2008
19
Activity of superoxide dismutase and level of lipid peroxidation in pneumoconiosis patients]. (17908436)
2007
20
Long-term outcome after resection of non-small cell lung carcinoma complicated by pneumoconiosis. (16998679)
2006
21
Relationship between pneumoconiosis and the polymorphisms of HLA-DRB1*, DQB1* genes]. (16188098)
2005
22
Changing patterns of pneumoconiosis mortality--United States, 1968-2000. (15269698)
2004
23
Pneumoconiosis in rush mat workers exposed to clay dye "sendo" dust: clinical, radiologic, and histopathologic features in seven patients. (14769759)
2004
24
Tumor necrosis factor-alpha gene promoter polymorphism in coal workers' pneumoconiosis. (12162435)
2002
25
Centennial photo page. Silicosis and a few of the other pneumoconiosies: observations on certain aspects of the problem, with emphasis on the role of the radiologist. 1958. (10915663)
2000
26
Mineralogy of lung tissue in dental laboratory technicians' pneumoconiosis. (10386356)
1999
27
Silicate pneumoconiosis in pigs: optical and scanning electron microscopical investigations with X-ray microanalysis. (8040388)
1994
28
Fuller's earth (montmorillonite) pneumoconiosis. (7951799)
1994
29
Complexation of iron by humic-like substances in lung tissue: role in coal workers' pneumoconiosis. (8074240)
1994
30
Coal workers' pneumoconiosis. (1511552)
1992
31
Lung cancer risk among pneumoconiosis patients in Japan, with special reference to silicotics. (2164508)
1990
32
Radiographic type p pneumoconiosis: high-resolution CT. (2928514)
1989
33
Siliceous pneumoconiosis in two dogs. (2715401)
1989
34
Pneumoconiosis in an elderly dentist. (3371114)
1988
35
Pneumoconiosis in carbon electrode workers. (3230438)
1988
36
Lung and blood lymphocyte subsets in asbestosis and in mixed dust pneumoconiosis. (3792062)
1987
37
A case-control study to investigate the association between indices of dust exposure and the development of radiologic pneumoconiosis. (3439812)
1987
38
Epidemiologic studies of Scottish oil shale workers: II. Lung function in shale workers' pneumoconiosis. (3717167)
1986
39
Quantitative relations between exposure to respirable coalmine dust and coalworkers' simple pneumoconiosis in men who have worked as miners but have left the coal industry. (3718902)
1986
40
Morphology and pathogenesis of pneumoconiosis in dental technicians. (4001030)
1985
41
An application of kappa-type analyses to interobserver variation in classifying chest radiographs for pneumoconiosis. (6729290)
1984
42
Antimoniosis: a particular form of pneumoconiosis. I. Etiology, clinical and X-ray findings. (6222000)
1983
43
Does coal workers' pneumoconiosis predict to lung cancer? Some evidence from a case-control study. (6632816)
1983
44
Epidemiologic and histologic observations on lung cancer in pneumoconiosis population. (7172143)
1982
45
Irregular opacities in coalworkers' pneumoconiosis--correlation with pulmonary function and pathology. (7181305)
1982
46
Nepheline rock dust pneumoconiosis. A report of 2 cases. (7053544)
1982
47
Graphite pneumoconiosis of electrotypers. (5954455)
1966
48
Farmer's lung; a form of pneumoconiosis due to organic dusts. (13498211)
1958
49
Kaolin pneumoconiosis. (13577154)
1958
50

Variations for Pneumoconiosis

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Expression for genes affiliated with Pneumoconiosis

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Search GEO for disease gene expression data for Pneumoconiosis.

Pathways for genes affiliated with Pneumoconiosis

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Pathways related to Pneumoconiosis according to GeneCards Suite gene sharing:

(show top 50)    (show all 65)
idSuper pathwaysScoreTop Affiliating Genes
19.7IL1B, IL6, TGFB1
29.7CCL2, IL1B, TNF
39.7CCL2, IL1B, TNF
49.6CXCL8, IL6, TNF
59.6CXCL8, FN1, TGFB1
69.6CXCL8, FASLG, FN1
79.5CCL2, CXCL8, IL6
89.5FAS, FASLG, TNF
99.5IL1B, IL6, TGFB1, TNF
10
Show member pathways
9.5IL1B, IL6, TGFB1, TNF
11
Show member pathways
9.5CAT, FASLG, IL6, TGFB1
129.4CXCL8, IL1B, IL6, TNF
13
Show member pathways
9.2FAS, FASLG, TGFB1, TNF
149.2FAS, IL6, TGFB1, TNF
15
Show member pathways
9.1CCL2, FN1, IL1B, IL6, TNF
168.9IL1A, IL1B, TGFB1, TNF
178.9FAS, FASLG, IL1B, IL6, TNF
188.9IL1A, IL1B, IL6, TNF
198.9IL1A, IL1B, IL6, TNF
208.9CXCL8, FN1, IL1B, IL6, TGFB1, TNF
218.8CCL2, FAS, IL1B, IL6, TNF
228.8CCL2, CXCL8, IL1B, IL6, TGFB1, TNF
23
Show member pathways
8.8CXCL8, IL1A, IL1B, IL6
248.6FAS, FASLG, FN1, IL6, TGFB1, TNF
258.6IL1A, IL1B, IL6, TGFB1, TNF
268.6IL1A, IL1B, IL6, TGFB1, TNF
27
Show member pathways
8.6CCL2, CXCL8, IL1B, IL6, NLRP3, TNF
28
Show member pathways
8.6CAT, CCL2, IL1B, IL6, SOD1, TNF
298.6FASLG, IL1A, IL1B, IL6, TNF
308.6IL1A, IL1B, IL6, SOD1
31
Show member pathways
8.6CXCL8, IL1A, IL1B, IL6, TNF
32
Show member pathways
8.6CXCL8, IL1A, IL1B, IL6, TNF
338.5CXCL8, FAS, FASLG, FN1, IL6, TGFB1
34
Show member pathways
8.4FAS, FASLG, IL1A, IL1B, TNF
35
Show member pathways
8.3CXCL8, FAS, FASLG, FN1, IL1B, IL6
368.3CXCL8, FN1, IL1A, IL1B, IL6, TGFB1
378.1FAS, FASLG, IL1A, IL1B, TGFB1, TNF
388.1CXCL8, IL1A, IL1B, IL6, NLRP3, TNF
398.1CXCL8, IL1A, IL1B, IL6, NLRP3, TNF
40
Show member pathways
8.1FAS, IL1A, IL1B, IL6, TGFB1, TNF
41
Show member pathways
8.0CCL2, CXCL8, FAS, FASLG, IL1B, IL6
428.0CCL2, CXCL8, IL1A, IL1B, IL6, TGFB1
438.0CCL2, CXCL8, IL1A, IL1B, IL6, TGFB1
44
Show member pathways
7.8FAS, FASLG, IL1A, IL1B, IL6, TGFB1
457.7CCL2, CXCL8, FN1, IL1A, IL1B, IL6
46
Show member pathways
7.5CP, CXCL8, IL1A, IL1B, IL6, MUC5B
47
Show member pathways
7.5CXCL8, FAS, FASLG, IL1A, IL1B, IL6
48
Show member pathways
7.2CCL2, CXCL8, FAS, FASLG, IL1A, IL1B
49
Show member pathways
7.2CCL2, CXCL8, FAS, FASLG, IL1A, IL1B
50
Show member pathways
7.0CCL2, CXCL8, FAS, FASLG, IL1A, IL1B

GO Terms for genes affiliated with Pneumoconiosis

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Biological processes related to Pneumoconiosis according to GeneCards Suite gene sharing:

(show top 50)    (show all 75)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of calcidiol 1-monooxygenase activityGO:006055910.7IL1B, TNF
2sequestering of triglycerideGO:003073010.7IL1B, TNF
3regulation of establishment of endothelial barrierGO:190314010.7IL1B, TNF
4response to L-ascorbic acidGO:003359110.7CAT, IL1B
5epithelial cell proliferation involved in salivary gland morphogenesisGO:006066410.7IL6, TNF
6negative regulation of lipid storageGO:001088810.6IL6, TNF
7positive regulation of T-helper 2 cell differentiationGO:004563010.5IL6, NLRP3
8interleukin-1 beta productionGO:003261110.5IL1B, NLRP3
9positive regulation of superoxide anion generationGO:003293010.4SOD1, TGFB1
10positive regulation of nitric oxide biosynthetic processGO:004542910.4IL1B, IL6, TNF
11myeloid cell homeostasisGO:000226210.3IL6, SOD1
12negative regulation of fat cell differentiationGO:004559910.3IL6, TGFB1, TNF
13positive regulation of sequence-specific DNA binding transcription factor activityGO:005109110.2IL1B, IL6, TNF
14positive regulation of peptidyl-serine phosphorylationGO:003313810.2IL6, TGFB1, TNF
15positive regulation of protein kinase B signalingGO:005189710.2IL6, TGFB1, TNF
16necroptotic signaling pathwayGO:009752710.2FAS, FASLG, TNF
17fever generationGO:000166010.1IL1A, IL1B
18positive regulation of interleukin-6 productionGO:003275510.1IL1B, IL6, TNF
19lipopolysaccharide-mediated signaling pathwayGO:003166310.0CCL2, IL1B, TGFB1
20positive regulation of ERK1 and ERK2 cascadeGO:007037410.0CCL2, IL1B, IL6
21neutrophil chemotaxisGO:003059310.0CCL2, CXCL8, IL1B
22response to antibioticGO:004667710.0CCL2, IL6, SOD1
23cellular response to dexamethasone stimulusGO:00715499.9CCL2, IL6, TGFB1
24cellular response to glucose stimulusGO:00713339.8FAS, FN1, IL1B
25response to woundingGO:00096119.8CCL2, FN1, IL6, TGFB1
26negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:20012409.8IL1A, IL1B, TNF
27MAPK cascadeGO:00001659.8CCL2, IL1B, TGFB1, TNF
28cellular response to organic cyclic compoundGO:00714079.7CCL2, FAS, TGFB1, TNF
29activation of cysteine-type endopeptidase activity involved in apoptotic processGO:00069199.7FAS, FASLG, TNF
30response to ozoneGO:00101939.7CAT, FN1, IL1B, SCGB1A1
31response to cytokineGO:00340979.6FAS, IL6, SCGB1A1
32extrinsic apoptotic signaling pathwayGO:00971919.6FAS, FASLG, TGFB1, TNF
33response to heatGO:00094089.6CCL2, IL1B, IL6
34positive regulation of apoptotic processGO:00430659.6FAS, IL1B, IL6, TNF
35platelet activationGO:00301689.5FN1, IL6, SOD1, TGFB1
36extrinsic apoptotic signaling pathway in absence of ligandGO:00971929.5FAS, IL1A, IL1B
37positive regulation of NF-kappaB transcription factor activityGO:00510929.4CAT, IL1B, IL6, NLRP3, TNF
38response to organic substanceGO:00100339.3SCGB1A1, TGFB1, TNF
39cytokine-mediated signaling pathwayGO:00192219.3CCL2, IL1A, IL1B, IL6
40negative regulation of transcription from RNA polymerase II promoterGO:00001229.2FASLG, IL1B, SCGB1A1, TGFB1, TNF
41response to glucocorticoidGO:00513849.1CCL2, FAS, FN1, IL1B, IL6, TNF
42cellular response to tumor necrosis factorGO:00713569.1CCL2, CXCL8, FAS, IL6
43negative regulation of cysteine-type endopeptidase activity involved in apoptotic processGO:00431549.1FAS, FASLG, IL6
44cellular response to lipopolysaccharideGO:00712229.0CCL2, CXCL8, FN1, IL1B, IL6, TNF
45response to lipopolysaccharideGO:00324968.6FAS, FASLG, IL1B, IL6, SCGB1A1
46positive regulation of gene expressionGO:00106288.6FN1, IL1A, IL1B, IL6, TGFB1
47inflammatory responseGO:00069548.6IL1A, IL1B, IL6, NLRP3, TGFB1, TNF
48response to drugGO:00424938.3CAT, CCL2, IL1B, IL6, SCGB1A1, SOD1
49agingGO:00075688.3CAT, CCL2, CP, FAS, IL1B, IL6
50immune responseGO:00069557.7CCL2, CXCL8, FAS, FASLG, IL1A, IL1B

Sources for Pneumoconiosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet