MCID: PNM006
MIFTS: 50

Pneumoconiosis malady

Respiratory diseases category
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Summaries for Pneumoconiosis

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Wikipedia:65 Pneumoconiosis is an occupational lung disease and a restrictive lung disease caused by the inhalation... more...

MalaCards based summary: Pneumoconiosis is related to anthracosis and tuberculosis. An important gene associated with Pneumoconiosis is SOD1 (superoxide dismutase 1, soluble), and among its related pathways are Oxidative Stress and Amyotrophic lateral sclerosis (ALS). The compounds nickel carbonate hydroxide and fpl 55712 have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and monocytes.

Disease Ontology:8 An interstitial lung disease that is caused by the inhalation of dust.

Aliases & Classifications for Pneumoconiosis

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Sources:
8Disease Ontology, 44Novoseek, 62UMLS, 34MeSH, 57SNOMED-CT, 39NCIt, 27ICD9CM, 25ICD10
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Related Diseases for Pneumoconiosis

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Diseases in the Pneumoconiosis family:

Pneumoconiosis Due to Talc

Diseases related to Pneumoconiosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 76)
idRelated DiseaseScoreTop Affiliating Genes
1anthracosis31.2SOD1, CCL2
2tuberculosis31.1CP
3hemosiderosis30.6CP
4pulmonary fibrosis30.4CCL2, SOD1
5pulmonary tuberculosis30.2CP, CAT
6silicosis10.7
7graphite pneumoconiosis10.6
8caplan's syndrome10.5
9lung cancer10.5
10eales disease10.5SOD1
11hypermethioninemia10.5SOD1
12asbestosis10.5
13aceruloplasminemia10.5CP
14diabetic cataract10.4CAT
15kaolin pneumoconiosis10.4
16pulmonary function10.3
17menkes disease10.3SOD1, CP
18senile cataract10.3SOD1, CAT
19chronic granulomatous disease10.3SOD1, CAT
20alcoholic liver cirrhosis10.3CAT, SOD1
21gastritis10.2CAT
22arthritis10.2
23rheumatoid arthritis10.2
24byssinosis10.2
25pneumoconiosis due to talc10.2
26baritosis10.2
27arteriosclerosis10.2SOD1, CCL2
28vitiligo10.2CAT, SOD1
29male infertility10.2SOD1, CAT
30spiradenoma10.2CCL2, CAT
31chronic obstructive pulmonary disease10.2
32bronchitis10.2
33slate pneumoconiosis10.2
34berylliosis10.2
35mixed mineral dust pneumoconiosis10.2
36labrador lung10.2
37silicosiderosis10.2
38hyperhomocysteinemia10.2SOD1, CCL2
39prion disease10.2CAT, CP
40wilson disease10.1CP, SOD1, CAT
41asthma10.1CCL2, CP
42parkinson's disease10.1CAT, CP, SOD1
43idiopathic pulmonary fibrosis10.1
44pneumonia10.1
45sarcoidosis10.1
46mycobacterium malmoense10.1
47cork-handlers' disease10.1SOD1, CAT, CCL2
48vascular disease10.1SOD1, CAT, CCL2
49primary hyperoxaluria10.0SOD1, CCL2, CAT
50encephalitis10.0CAT, CCL2

Graphical network of the top 20 diseases related to Pneumoconiosis:



Diseases related to pneumoconiosis

Symptoms for Pneumoconiosis

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Drugs & Therapeutics for Pneumoconiosis

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Drug clinical trials:

Search ClinicalTrials for Pneumoconiosis

Search NIH Clinical Center for Pneumoconiosis

Genetic Tests for Pneumoconiosis

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Anatomical Context for Pneumoconiosis

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MalaCards organs/tissues related to Pneumoconiosis:

32
Lung, Testes, Monocytes, Eye, Liver, Skin, Neutrophil

Animal Models for Pneumoconiosis or affiliated genes

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Publications for Pneumoconiosis

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Articles related to Pneumoconiosis:

(show top 50)    (show all 557)
idTitleAuthorsYear
1
Prevalence of pneumoconiosis in Hubei, China from 2008 to 2013. (25158135)
2014
2
Comparison of High-resolution Computerized Tomography with Film-screen Radiography for the Evaluation of Opacity and the Recognition of Coal Workers' Pneumoconiosis. (24953093)
2014
3
Small mine size is associated with lung function abnormality and pneumoconiosis among underground coal miners in Kentucky, Virginia and West Virginia. (25052085)
2014
4
Mixed pneumoconiosis due to silicates and hard metals associated with primary SjAPgren's syndrome due to silica. (24626278)
2014
5
Associations between tumor necrosis factor alpha gene -238 G/A and -308 G/A polymorphisms and the risk of pneumoconiosis: update of a meta-analysis. (23919499)
2013
6
Mixed dust pneumoconiosis occurring in an unusual setting. (24296771)
2013
7
Pneumoconiosis. (23708110)
2013
8
Interleukin gene polymorphisms in pneumoconiosis. (22580886)
2012
9
Miners compensated for pneumoconiosis and glutathione s-transferases M1 and T1 genotypes. (22686319)
2012
10
Functional state of RBC and neutrophils in pneumoconiosis patients variable in tolerance to dust factor in after contact period]. (22242279)
2011
11
Denim sandblasters' pneumoconiosis. (21466064)
2011
12
Rheumatoid pneumoconiosis (Caplan's syndrome). (20493416)
2010
13
What component of coal causes coal workers' pneumoconiosis? (19333134)
2009
14
Coal workers' pneumoconiosis-related years of potential life lost before age 65 years - United States, 1968-2006. (20032926)
2009
15
Airway function and respiratory resistance in Taiwanese coal workers with simple pneumoconiosis. (19664351)
2009
16
Cytogenetic monitoring of coal workers and patients with coal workers' pneumoconiosis in Turkey. (18288720)
2008
17
Clinical study on pneumoconiosis with pulmonary thromboembolism]. (18302891)
2008
18
Activity of superoxide dismutase and level of lipid peroxidation in pneumoconiosis patients]. (17908436)
2007
19
Long-term outcome after resection of non-small cell lung carcinoma complicated by pneumoconiosis. (16998679)
2006
20
Relationship between pneumoconiosis and the polymorphisms of HLA-DRB1*, DQB1* genes]. (16188098)
2005
21
Changing patterns of pneumoconiosis mortality--United States, 1968-2000. (15269698)
2004
22
Pneumoconiosis in rush mat workers exposed to clay dye "sendo" dust: clinical, radiologic, and histopathologic features in seven patients. (14769759)
2004
23
Tumor necrosis factor-alpha gene promoter polymorphism in coal workers' pneumoconiosis. (12162435)
2002
24
Centennial photo page. Silicosis and a few of the other pneumoconiosies: observations on certain aspects of the problem, with emphasis on the role of the radiologist. 1958. (10915663)
2000
25
Mineralogy of lung tissue in dental laboratory technicians' pneumoconiosis. (10386356)
1999
26
Silicate pneumoconiosis in pigs: optical and scanning electron microscopical investigations with X-ray microanalysis. (8040388)
1994
27
Fuller's earth (montmorillonite) pneumoconiosis. (7951799)
1994
28
Complexation of iron by humic-like substances in lung tissue: role in coal workers' pneumoconiosis. (8074240)
1994
29
Coal workers' pneumoconiosis. (1511552)
1992
30
Lung cancer risk among pneumoconiosis patients in Japan, with special reference to silicotics. (2164508)
1990
31
Pneumoconiosis (silicosis) in the confectionery industry. (2345825)
1990
32
Radiographic type p pneumoconiosis: high-resolution CT. (2928514)
1989
33
Siliceous pneumoconiosis in two dogs. (2715401)
1989
34
Resting gas exchange in nonsmoking bituminous-coal miners with simple pneumoconiosis. (2500687)
1989
35
Pneumoconiosis in an elderly dentist. (3371114)
1988
36
Pneumoconiosis in carbon electrode workers. (3230438)
1988
37
Lung and blood lymphocyte subsets in asbestosis and in mixed dust pneumoconiosis. (3792062)
1987
38
A case-control study to investigate the association between indices of dust exposure and the development of radiologic pneumoconiosis. (3439812)
1987
39
Epidemiologic studies of Scottish oil shale workers: II. Lung function in shale workers' pneumoconiosis. (3717167)
1986
40
Quantitative relations between exposure to respirable coalmine dust and coalworkers' simple pneumoconiosis in men who have worked as miners but have left the coal industry. (3718902)
1986
41
Morphology and pathogenesis of pneumoconiosis in dental technicians. (4001030)
1985
42
An application of kappa-type analyses to interobserver variation in classifying chest radiographs for pneumoconiosis. (6729290)
1984
43
Antimoniosis: a particular form of pneumoconiosis. I. Etiology, clinical and X-ray findings. (6222000)
1983
44
Does coal workers' pneumoconiosis predict to lung cancer? Some evidence from a case-control study. (6632816)
1983
45
Epidemiologic and histologic observations on lung cancer in pneumoconiosis population. (7172143)
1982
46
Irregular opacities in coalworkers' pneumoconiosis--correlation with pulmonary function and pathology. (7181305)
1982
47
Nepheline rock dust pneumoconiosis. A report of 2 cases. (7053544)
1982
48
Graphite pneumoconiosis of electrotypers. (5954455)
1966
49
Farmer's lung; a form of pneumoconiosis due to organic dusts. (13498211)
1958
50
Kaolin pneumoconiosis. (13577154)
1958

Variations for Pneumoconiosis

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Expression for genes affiliated with Pneumoconiosis

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Expression patterns in normal tissues for genes affiliated with Pneumoconiosis

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Pathways for genes affiliated with Pneumoconiosis

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Pathways related to Pneumoconiosis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.7CAT, SOD1
2
Show member pathways
Amyotrophic lateral sclerosis (ALS)37
9.7CAT, SOD1
39.7CAT, SOD1
4
Show member pathways
9.7SOD1, CAT
5
Show member pathways
Vitamin B12 Metabolism37
9.7SOD1, CAT
69.7CAT, SOD1
7
Show member pathways
9.7CAT, SOD1
8
Show member pathways
thioredoxin pathway37
9.3SOD1, CCL2, CAT
9
Show member pathways
9.2SOD1, CP, HSPA1L

Compounds for genes affiliated with Pneumoconiosis

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Sources:
44Novoseek, 11DrugBank, 24HMDB
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Compounds related to Pneumoconiosis according to GeneCards/GeneDecks:

(show top 50)    (show all 107)
idCompoundScoreTop Affiliating Genes
1nickel carbonate hydroxide4410.1SOD1, CAT
2fpl 557124410.1CAT, SOD1
3u 83836e4410.1CAT, SOD1
4bathocuproine4410.1SOD1, CAT
5randox4410.1SOD1, CP
61,3-dimethyl-2-thiourea4410.1CAT, SOD1
7n-(2-mercaptopropionyl)glycine4410.1CAT, SOD1
8ionol4410.1SOD1, CAT
9alpha-phenyl-n-tert-butylnitrone4410.1CAT, SOD1
10tempol4410.1SOD1, CAT
11trimetazidine4410.1SOD1, CAT
12oxypurinol4410.0SOD1, CAT
13pyrogallol4410.0SOD1, CAT
14zinc superoxide4410.0SOD1, CAT
15benzoate4410.0SOD1, CAT
16propyl gallate4410.0CAT, SOD1
17ptio449.9SOD1, CAT
18diphenyliodonium449.9SOD1, CAT
19nacn449.9CAT, SOD1
20dmpo-oh449.8CP, CAT, SOD1
21dmpo449.8CAT, SOD1, CP
22thiobarbituric acid449.8CAT, SOD1, CP
23sodium azide449.8CP, SOD1, CAT
24azide449.8CP, SOD1, CAT
25fenton449.8CAT, SOD1, CP
26dehydroascorbic acid44 1110.8CAT, SOD1, CP
27dtpa449.8CP, CAT, SOD1
28tocopherol449.8SOD1, CP, CAT
29s-nitroso-n-acetylpenicillamine449.8CP, SOD1, CAT
30deferoxamine44 1110.8CAT, CP, SOD1
31hypoxanthine44 24 1111.7CAT, SOD1, CP
32selenium44 2410.7CP, SOD1, CAT
33betacarotene449.7CP, SOD1, CAT
34thiourea449.7SOD1, CAT
35semiquinone449.7SOD1, CAT
36malondialdehyde449.7CP, SOD1, CAT
37probucol44 1110.7SOD1, CCL2, CAT
388-isoprostane449.7SOD1, CCL2, CAT
39uric acid44 2410.7SOD1, CP, CAT
40alpha lipoic acid449.7CAT, CCL2, SOD1
41diphenyleneiodonium449.7CCL2, CAT, SOD1
42levodopa44 1110.6SOD1, CP, CAT
43vitamin-e449.6CP, SOD1, CAT
44citrinin449.6CAT, SOD1
45alpha tocopherol449.6CAT, SOD1, CP
46sodium nitroprusside449.5CP, SOD1, CAT
47mannitol44 1110.4CAT, CP, SOD1
48pdtc449.3CP, SOD1, CAT, CCL2
49superoxide44 2410.1CAT, SOD1, CP, CCL2
50egcg449.0SOD1, CCL2, CAT

GO Terms for genes affiliated with Pneumoconiosis

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Cellular components related to Pneumoconiosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1peroxisomeGO:0057779.7CAT, SOD1
2mitochondrial intermembrane spaceGO:0057589.4CAT, SOD1

Biological processes related to Pneumoconiosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to ethanolGO:0454719.7CCL2, SOD1
2response to heatGO:0094089.6CCL2, SOD1
3cellular iron ion homeostasisGO:0068799.5SOD1, CP

Molecular functions related to Pneumoconiosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1copper ion bindingGO:0055079.8SOD1, CP
2chaperone bindingGO:0510879.5SOD1, CP

Products for genes affiliated with Pneumoconiosis

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  • Antibodies
  • Proteins
  • Lysates

Sources for Pneumoconiosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet