MCID: PNM007
MIFTS: 78

Pneumonia malady

Respiratory diseases category
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Summaries for Pneumonia

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MedlinePlus:33 Pneumonia is an infection in one or both of the lungs. many germs, such as bacteria, viruses, and fungi, can cause pneumonia. you can also get pneumonia by inhaling a liquid or chemical. people most at risk are older than 65 or younger than 2 years of age, or already have health problems. symptoms of pneumonia vary from mild to severe. see your doctor promptly if you have a high fever have shaking chills have a cough with phlegm that doesn't improve or gets worse develop shortness of breath with normal daily activities have chest pain when you breathe or cough feel suddenly worse after a cold or the flu your doctor will use your medical history, a physical exam, and lab tests to diagnose pneumonia. treatment depends on what kind you have. if bacteria are the cause, antibiotics should help. if you have viral pneumonia, your doctor may prescribe an antiviral medicine to treat it. preventing pneumonia is always better than treating it. vaccines are available to prevent pneumococcal pneumonia and the flu. other preventive measures include washing your hands frequently and not smoking. nih: national heart, lung, and blood institute

MalaCards based summary: Pneumonia, also known as acute pneumonia, is related to bronchiolitis obliterans and desquamative interstitial pneumonia. An important gene associated with Pneumonia is CRP (C-reactive protein, pentraxin-related), and among its related pathways are Immune response Oncostatin M signaling via JAK Stat in human cells and IL-9 Signaling and its Primary Biological Effects in Different Immune Cell Types. The drugs acetylcysteine and oxygen and the compounds sivelestat and salmeterol have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and liver, and related mouse phenotypes are tumorigenesis and cardiovascular system.

Disease Ontology:8 A lung disease that involves lung parenchyma or alveolar inflammation and abnormal alveolar filling with fluid (consolidation and exudation). it results from a variety of causes including infection with bacteria, viruses, fungi or parasites, and chemical or physical injury to the lungs. it is accompanied by fever, chills, cough, and difficulty in breathing.

CDC:3 Pneumocystis pneumonia (PCP) is a serious illness caused by the fungus Pneumocystis jirovecii. PCP is one of the most frequent and severe opportunistic infections in people with weakened immune systems, particularly people with HIV/AIDS. Although people with HIV/AIDS are less likely to get PCP today than in recent years, PCP is still a significant public health problem.

Wikipedia:65 Pneumonia is an inflammatory condition of the lung affecting primarily the microscopic air sacs known as... more...

Aliases & Classifications for Pneumonia

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Related Diseases for Pneumonia

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Diseases in the Pneumonia family:

Viral Pneumonia

Diseases related to Pneumonia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 890)
idRelated DiseaseScoreTop Affiliating Genes
1bronchiolitis obliterans32.1IL8, CXCR3
2desquamative interstitial pneumonia32.0TNC
3bronchiolitis31.9IL13, IL8, IL5, CCL11, RNASE3
4chronic eosinophilic pneumonia31.8IL5, CCL11, RNASE3
5eosinophilic pneumonia31.6IL13, IL5, CCL11, CCL22, CCL17, RNASE3
6bacteremia31.6CRP, LACTB
7endophthalmitis31.5LACTB
8interstitial lung disease31.4CCL2, SFTPD
9asthma31.4IL13, CCL11
10meningitis31.4CRP, IL6, IL8, LACTB
11conjunctivitis31.4RNASE3
12respiratory failure31.3SFTPD, PIK3C2A
13otitis media31.3CCL11, RNASE3, LACTB
14mediastinitis31.2CRP
15influenza31.2IFNG, CCL11, CXCR3, NEU1, LACTB, SFTPD
16arthritis31.1IL6, IL8
17septic arthritis31.1CRP
18pulmonary alveolar proteinosis31.1CCL2, SFTPC, SFTPD
19dysphagia31.1PIK3C2A
20adult respiratory distress syndrome31.0IL8, ELANE
21aspergillosis31.0IFNG, ELANE, SFTPD
22exanthem31.0CRP
23pharyngitis31.0LACTB
24bacteriuria31.0CRP
25rhinitis30.9IL13, IL8, IL5, CCL11, RNASE3
26vascular disease30.9CRP, CCL2, ELANE, TNC
27esophagitis30.9IL13, IL5, CCL11
28tuberculosis30.9CRP, IFNG, CCR4, CXCR3, LACTB, SFTPD
29adult-onset still's disease30.9CRP, IL6
30churg-strauss syndrome30.8IL5, RNASE3
31allergic bronchopulmonary aspergillosis30.8IL5, SFTPD
32prostatitis30.8LACTB
33aortic aneurysm30.8CRP
34bronchiectasis30.8IL8, ELANE, RNASE3
35vasculitis30.8CRP, CCL2, ELANE
36colitis30.7IL13, IL6, IL8, IFNG
37sinusitis30.7IL5, CCL11, RNASE3, LACTB
38gastroenteritis30.7LACTB
39pyelonephritis30.7CRP, LACTB
40osteomyelitis30.7CRP, LACTB
41chronic obstructive pulmonary disease30.7CRP, IL6, SFTPD
42paragonimiasis30.7IL5, CCL17
43bronchitis30.7IL8, IL5, CCL11, ELANE, RNASE3, LACTB
44pelvic inflammatory disease30.7CRP, LACTB
45leukemia30.6IL6, IFNG, CCL11, CXCR3, RNASE3, LACTB
46peritonitis30.6CRP, IL6, CCL2, LACTB
47pulmonary hypertension30.6ELANE, TNC, SFTPC
48lung cancer30.6CCL22, CCR4, CXCR3, TNC, SFTPD
49malaria30.6IFNG, NEU1
50pancreatitis30.6CRP, IL6, ELANE

Graphical network of the top 20 diseases related to Pneumonia:



Diseases related to pneumonia

Symptoms for Pneumonia

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Drugs & Therapeutics for Pneumonia

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Drug clinical trials:

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Genetic Tests for Pneumonia

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Anatomical Context for Pneumonia

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MalaCards organs/tissues related to Pneumonia:

32
Lung, Testes, Liver, Heart, Endothelial, Neutrophil, T cells, Bone, Bone marrow, Breast, Colon, Monocytes, Brain, Smooth muscle, Myeloid, Kidney, Skin, B cells, Prostate, Tonsil, Eye, Thymus, Thyroid, Nk cells, Pituitary, Bronchial epithelium, Whole blood, Lymph node, Spleen, Uterus, Tongue, Pancreatic islet

Animal Models for Pneumonia or affiliated genes

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MGI Mouse Phenotypes related to Pneumonia:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.8SFTPC, CXCR3, ELANE, CCL2, IFNG, IL5
2MP:00053858.7NEU1, CXCR3, CCL2, IFNG, IL6, CRP
3MP:00053888.0SFTPD, SFTPC, NEU1, CXCR3, CCR4, CCL11
4MP:00053787.8PIK3C2A, SFTPD, SFTPC, NEU1, CCL2, IFNG
5MP:00107687.6PIK3C2A, SFTPD, SFTPC, NEU1, CXCR3, ELANE
6MP:00053767.3CXCR3, NEU1, TNC, SFTPD, PIK3C2A, ELANE
7MP:00053976.7CCL17, ELANE, CXCR3, NEU1, SFTPD, PIK3C2A
8MP:00053876.4CRP, PIK3C2A, SFTPD, SFTPC, NEU1, CXCR3

Publications for Pneumonia

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Articles related to Pneumonia:

(show top 50)    (show all 5263)
idTitleAuthorsYear
1
Mutant prevention concentrations of colistin for Acinetobacter baumannii, Pseudomonas aeruginosa and Klebsiella pneumoniae clinical isolates. (23997018)
2014
2
Daptomycin-Associated Eosinophilic Pneumonia in Two Patients with Prosthetic Joint Infection. (25317960)
2014
3
Strategies to prevent ventilation-associated pneumonia: the effect of cuff pressure monitoring techniques and tracheal tube type on aspiration of subglottic secretions: An in-vitro study. (24270899)
2013
4
Genome Sequence of Klebsiella pneumoniae Strain ATCC 25955, an Oxygen-Insensitive Producer of 1,3-Propanediol. (23929480)
2013
5
Tracheal bronchus associated with recurrent pneumonia. (24082287)
2013
6
Community-acquired pneumonia versus healthcare-associated pneumonia. The returning pendulum. (24127797)
2013
7
Soluble B7-H3 elevations in hospitalized children with Mycoplasma pneumoniae pneumonia. (24139879)
2013
8
Inhibition of Klebsiella pneumoniae Growth and Capsular Polysaccharide Biosynthesis by Fructus mume. (24062785)
2013
9
Daptomycin-induced acute eosinophilic pneumonia: analysis of the current data and illustrative case reports. (23826793)
2013
10
Detection of clonal KPC-2-producing Klebsiella pneumoniae ST258 in Korea during nationwide surveillance in 2011. (23741020)
2013
11
Chronic Eosinophilic Pneumonia in a Breast Cancer Patient Post Radiation Therapy: A Case Report. (24026185)
2013
12
Risk factors for treatment failure of polymyxin B monotherapy for carbapenem-resistant Klebsiella pneumoniae infections. (23959321)
2013
13
Cough Sound Analysis - A new tool for diagnosing Pneumonia. (24110911)
2013
14
Cryptogenic organizing pneumonia during adjuvant chemotherapy with oxaliplatin, 5-fluorouracil, and leucovorin (FOLFOX) for colon cancer. (22842502)
2013
15
Single-Day Trimethoprim/Sulfamethoxazole Prophylaxis for Pneumocystis Pneumonia in Children with Cancer. (24252793)
2013
16
A case of adult-onset Still's disease complicated by hemophagocytic syndrome and interstitial pneumonia with pneumomediastinum/recurrent pneumothorax. (22898226)
2012
17
Postoperative meningitis and epidural abscess due to extended-spectrum I^-lactamase-producing Klebsiella pneumoniae: a case report and a review of the literature. (22989843)
2012
18
Mycoplasma pneumoniae infection associated with urticarial vasculitis mimicking adult-onset Still's disease. (21918897)
2012
19
A 12 year old boy with recurrent episodes of pneumonia: triple A syndrome. (24834210)
2012
20
Abdominal infectious aortitis caused by Streptococcus pneumoniae: a case report and literature review. (20926247)
2011
21
Roles of capsule and lipopolysaccharide O antigen in interactions of human monocyte-derived dendritic cells and Klebsiella pneumoniae. (19841082)
2010
22
Organizing pneumonia in a patient with newly diagnosed acquired immunodeficiency syndrome. (21048369)
2010
23
Pneumocystis jirovecii pneumonia in a baby with hyper-IgE syndrome. (19308447)
2010
24
Mycoplasma pneumoniae--associated transverse myelitis and rhabdomyolysis. (19135630)
2009
25
Phosphodiesterase 2 inhibition diminished acute lung injury in murine pneumococcal pneumonia. (19114892)
2009
26
Review: pneumococcal vaccination does not prevent pneumonia, bacteraemia, bronchitis, or mortality. (19553411)
2009
27
Understanding nonspecific interstitial pneumonia: the need for a diagnostic gold standard. (19158329)
2009
28
Homology modeling of Mycoplasma pneumoniae enolase and its molecular interaction with human plasminogen. (19052661)
2008
29
Effect of regular intravenous immunoglobulin therapy on prevention of pneumonia in patients with common variable immunodeficiency. (16604243)
2006
30
Definitive techniques for intractable aspiration pneumonia. (16707166)
2006
31
Relationship between peripheral arterial occlusive disease (PAOD) and chronic Chlamydophila (Chlamydia) pneumoniae infection. A meta-analysis. (15968402)
2005
32
Squalene aspiration pneumonia in children: radiographic and CT findings as the first clue to diagnosis. (15806404)
2005
33
Fibroblastic foci in usual interstitial pneumonia. (14982825)
2004
34
The incidence and clinical characteristics of bronchiolitis obliterans organizing pneumonia syndrome after radiation therapy for breast cancer. (15554078)
2004
35
Community-acquired pneumonia--treatment perspectives in the physician's office]. (15373084)
2004
36
Predicting survival of lung transplantation candidates with idiopathic interstitial pneumonia: does PaO(2) predict survival? (12226013)
2002
37
Levels of interleukin-2, interferon-gamma, and interleukin-4 in bronchoalveolar lavage fluid from patients with Mycoplasma pneumonia: implication of tendency toward increased immunoglobulin E production. (11230620)
2001
38
Procalcitonin in pyelonephritis and acute community-acquired pneumonia in adults]. (11484399)
2001
39
Surfactant protein D and KL-6 as serologic indicators of Pneumocystis carinii pneumonia in a child with acute lymphoblastic leukemia. (11321887)
2001
40
Chlamydia pneumoniae infection of vascular smooth muscle and endothelial cells activates NF-kappaB and induces tissue factor and PAI-1 expression: a potential link to accelerated arteriosclerosis. (10500035)
1999
41
Usual interstitial pneumonia: relationship between disease activity and the progression of honeycombing at thin-section computed tomography. (9671423)
1998
42
Exogenous lipoid pneumonia complicated by Mycobacterium fortuitum and Aspergillus fumigatus infections. (8834351)
1996
43
Treatment of aspiration pneumonia with low-dose methylprednisolone and antibiotics]. (7699968)
1995
44
TNF and pneumonia. (7632260)
1994
45
Effect of ventilation with positive end-expiratory pressure on the development of lung damage in experimental acid aspiration pneumonia in the rabbit. (1613190)
1992
46
Pneumocystis carinii pneumonia complicating somatostatin therapy of Cushing's syndrome in a patient with metastatic pancreatic islet cell carcinoma and Zollinger-Ellison syndrome. (1672788)
1991
47
Serological evidence of viral or Mycoplasma pneumoniae infection in acute maxillary sinusitis. (2498094)
1989
48
Desquamative interstitial pneumonia. Computed tomographic findings before and after treatment with corticosteroids. (3335161)
1988
49
Desquamative interstitial pneumonia associated with granulomatous lymphadenopathy. (923315)
1977
50
Desquamative interstitial pneumonia. A form of muscular cirrhosis of the lung fibrosing alveolitis. (5555709)
1971

Variations for Pneumonia

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Expression for genes affiliated with Pneumonia

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Expression patterns in normal tissues for genes affiliated with Pneumonia

Search GEO for disease gene expression data for Pneumonia.

Pathways for genes affiliated with Pneumonia

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Pathways related to Pneumonia according to GeneCards/GeneDecks:

(show all 40)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.0CCL2, CCL11
29.8IL5, IL6, IL13
39.8IL8, IL6, CCL11
49.8CCL2, IL6, IL8
5
Show member pathways
9.8IL6, IL8, CCL2
69.8IL5, IL13, IFNG
7
Show member pathways
Calcium signaling in the CD4+ TCR pathway37
9.8IL8, IFNG, IL5
89.8IL5, CCL11, CCL17
99.8IL6, IFNG, IL8
109.8IL6, IL8, IFNG
119.8IL6, IL8, IFNG
12
Show member pathways
9.8IFNG, IL6, IL8
13
Show member pathways
Immune response MIF in innate immunity response60
9.8IFNG, IL6, IL8
149.8IL8, IL6, IFNG
15
Show member pathways
IL23-mediated signaling events37
Immune response IL 10 signaling pathway60
Angiopoietin receptor Tie2-mediated signaling37
Development PDGF signaling via STATs and NF kB60
Development Angiopoietin Tie2 signaling60
9.7IL6, IFNG, CCL2
169.6IL5, CCL11, IL8, IL6
17
Show member pathways
9.6PIK3C2A, IL5, IL13
18
Show member pathways
9.6IFNG, IL6, IL13, IL5
19
Show member pathways
Type III interferon signaling37
9.6IL6, IL13, IFNG, IL5
209.6IL6, IL5, IL13, IFNG
21
Show member pathways
thioredoxin pathway37
9.6IFNG, IL6, CRP, CCL2
22
Show member pathways
Toll-like receptor signaling pathway37
Regulation of toll-like receptor signaling pathway37
9.5IL8, IFNG, IL6, CCL2
239.5CCL2, IL6, IL8, IFNG
249.5IL8, IL6, CCL2, IFNG
259.5IL6, IL8, IFNG, CCL2
269.4IL8, IL5, IL13, IFNG, IL6
279.4IL8, IL6, IFNG, IL13, IL5
28
Show member pathways
Transcription NF kB signaling pathway60
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response60
9.4SFTPD, IL6, IFNG, CCL11, IL8
29
Show member pathways
9.4IL13, IL6, IL8, IFNG, CCL2
30
Show member pathways
9.1IL5, RNASE3, CCL11, IL6, IL13, IFNG
31
Show member pathways
8.5CCL2, CXCR3, CCR4, CCL22, CCL11, IL8
32
Show member pathways
8.5CCR4, IL8, CCL11, CCL22, CCL2, CXCR3
33
Show member pathways
8.5CCL22, CCL11, CCL2, IL8, CCR4, CCL17
34
Show member pathways
8.5CCR4, CCL22, CCL2, CCL11, IL8, CXCR3
35
Show member pathways
8.3IL8, CCL11, CCL22, CCL2, CCL17, IL13
36
Show member pathways
8.2CCL17, CXCR3, CCL2, CCR4, CCL22, CCL11
37
Show member pathways
7.9CXCR3, CCR4, IL13, IL8, IL5, IL6
38
Show member pathways
7.9IL13, CXCR3, CCL17, CCR4, CCL22, CCL2
39
Show member pathways
7.6IL8, TNC, CXCR3, IL13, IL6, CCL17
40
Show member pathways
7.6CCL2, CCR4, CXCR3, CCL11, IFNG, IL5

Compounds for genes affiliated with Pneumonia

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Compounds related to Pneumonia according to GeneCards/GeneDecks:

(show top 50)    (show all 236)
idCompoundScoreTop Affiliating Genes
1sivelestat449.8SFTPD, IL6, IL8, ELANE
2salmeterol44 50 28 1112.8IL8, IL13, CCL11, IL5, RNASE3
3montelukast44 50 28 1112.7IL8, RNASE3, CCL11, IL5, IL13
4mcp 1449.7IL8, IL6, CXCR3, CCL2, IL5
5cetirizine44 28 24 1112.7CCL11, IL5, IL8, RNASE3
6roxithromycin44 28 1111.7IL5, IL8, CCL17, CCL11
7salbutamol44 50 28 24 1113.7IL5, CCL11, IL8, IL13, RNASE3
8groalpha449.6CXCR3, CCL2, CCL11, IL8, IL13, IL6
9gabexate mesilate449.5ELANE, IL8, IL6, CRP
10il-12449.5CCL2, IL13, IL6, IL5, IL8, IFNG
11etanercept44 50 1111.5CRP, IL6, IL8, IFNG, CXCR3
12anaphylatoxin449.5IL8, RNASE3, ELANE, CCL2, IL6
13poly(i-c)449.5IL8, IL5, CCL11, IL6, IFNG
14budesonide44 50 1111.5IL13, IL8, IL5, IFNG, CCL11, RNASE3
15rolipram44 61 2811.4IL5, IFNG, CCL11, ELANE, IL8, IL13
16methacholine44 50 1111.4CRP, IL13, CCL22, IL8, CCL11, IL5
17fluticasone propionate44 50 61 1112.3RNASE3, ELANE, CCL11, IL13, IL8, IL5
18gm-csf44 2810.2IL13, IL6, IL8, IL5, IFNG, CCL2
19larc449.2CCL2, CCL17, CCR4, CXCR3, CCL22
20hydrocortisone44 2 61 1112.1IL13, CXCR3, IL6, IL8, IL5, IFNG
21herbimycin a44 6110.1IL5, IL8, IFNG, CCL11, CCL2, IL6
22allergens449.1CXCR3, SFTPD, RNASE3, CCL17, IL13, CCL11
23fmlp449.1ELANE, CXCR3, CCL11, IL5, IL8, IL13
24il 10449.1CCL17, CXCR3, CCL2, IFNG, IL13, IL6
25tacrolimus44 50 1111.0CCL22, CXCR3, CCL11, IFNG, IL5, IL13
26actinomycin d448.9TNC, SFTPC, CCL11, IL13, IL6, IL8
27ccl444 289.9CCR4, IL13, CCL11, CXCR3, CCL17, CCL2
28hyaluronic acid44 249.8ELANE, IL8, TNC, RNASE3, NEU1, CCL11
29sb 20358044 619.8CRP, IL13, IL8, IL5, IFNG, CCL11
30leukotriene b444 61 2410.8RNASE3, ELANE, CCL2, CCL22, CCL11, IL5
31simvastatin44 50 61 28 24 1113.7IFNG, CCL2, PIK3C2A, CCR4, IL8, IL6
32lactate448.6IL8, IL13, PIK3C2A, IL6, CRP, RNASE3
33cycloheximide448.5TNC, NEU1, CCL2, IFNG, IL5, IL8
34nitric oxide44 24 1110.5SFTPD, RNASE3, CXCR3, CCL17, IL13, IL6
35endotoxin448.4CRP, IFNG, CCL11, CCL2, ELANE, CXCR3
36ly294002448.4IL8, PIK3C2A, CXCR3, CCL11, IL5, CRP
37tarc448.3IL5, IL13, IL8, IFNG, CCL11, CCL22
38pge2448.3CXCR3, ELANE, CCL2, CCL22, CCL11, IFNG
39prednisolone44 28 1110.2SFTPD, RNASE3, CCR4, CCL11, IFNG, IL5
40ccl344 289.2CCL11, CCL22, CCR4, CCL2, CCL17, CXCR3
41heparin44 28 24 1111.1IL13, PIK3C2A, TNC, RNASE3, NEU1, CXCR3
42fibrinogen448.1PIK3C2A, SFTPC, TNC, RNASE3, ELANE, CCL17
43histamine44 28 2410.0SFTPD, IL5, IFNG, CCL11, CCL22, CCL2
44cyclosporin a44 28 619.9PIK3C2A, RNASE3, ELANE, CCL17, CCL22, CCL11
45retinoic acid44 248.8IL13, IL6, RNASE3, TNC, SFTPC, IL5
46rantes447.8RNASE3, IL8, CXCR3, IL13, CCL17, CCL2
47vegf447.7CRP, IL13, IL6, PIK3C2A, SFTPC, TNC
48dexamethasone44 50 28 1110.6CCL2, SFTPC, TNC, RNASE3, IL13, IL6
49lipid447.5SFTPD, SFTPC, TNC, CCL2, CCR4, CCL11
50calcium44 50 24 1110.0CCL22, PIK3C2A, SFTPD, SFTPC, RNASE3, CXCR3

GO Terms for genes affiliated with Pneumonia

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Cellular components related to Pneumonia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:0098979.1IL13, IL6, IFNG, CCR4, CXCR3
2extracellular spaceGO:0056157.2IL13, IL6, IL8, IL5, IFNG, CCL11
3extracellular regionGO:0055767.0CRP, SFTPD, IL13, IL6, IL8, IL5

Biological processes related to Pneumonia according to GeneCards/GeneDecks:

(show all 34)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of lipid storageGO:01088810.4CRP, IL6
2regulation of vascular endothelial growth factor productionGO:01057410.4IL6, CCL2
3positive regulation of immunoglobulin secretionGO:05102410.3IL6, IL5
4neutrophil apoptotic processGO:00178110.3IFNG, IL6
5negative regulation of chemokine biosynthetic processGO:04507910.3ELANE, IL6
6macrophage chemotaxisGO:04824610.3SFTPD, CCL2
7positive regulation of JAK-STAT cascadeGO:04642710.2IL5, IL6
8neutrophil chemotaxisGO:03059310.2IL8, IFNG, CCL2
9response to glucocorticoidGO:05138410.1IL6, CCL2, SFTPC
10cellular response to lipopolysaccharideGO:07122210.1CCL2, IFNG, IL8
11response to mechanical stimulusGO:00961210.1TNC, CCL2, IL6
12positive regulation of smooth muscle cell proliferationGO:04866110.1IL13, IL6, ELANE
13agingGO:00756810.1CCL2, IL6, CRP
14humoral immune responseGO:00695910.1IL6, IFNG, CCL2
15endoplasmic reticulum unfolded protein responseGO:03096810.1IL8, IFNG, CCL2
16response to ethanolGO:04547110.0TNC, CCL2, IL13, CRP
17regulation of cell shapeGO:00836010.0IL6, CCL11, CCL2
18defense response to protozoanGO:04283210.0IL6, IFNG
19cellular calcium ion homeostasisGO:00687410.0ELANE, CCL2, CCL11
20monocyte chemotaxisGO:00254810.0IL6, CCL2
21negative regulation of growth of symbiont in hostGO:04413010.0IFNG, ELANE
22cellular component movementGO:00692810.0IL13, IL8, IFNG, CXCR3
23cellular response to fibroblast growth factor stimulusGO:04434410.0CCL2, IL8
24response to antibioticGO:0466779.9CCL2, CCR4, IL6
25response to lipopolysaccharideGO:0324969.9IL13, IL6, ELANE, SFTPC
26defense response to bacteriumGO:0427429.9SFTPD, RNASE3, ELANE, IFNG
27cytokine-mediated signaling pathwayGO:0192219.8CCL2, IFNG, IL5, IL6
28response to virusGO:0096159.8IFNG, CCL11, CCL22
29response to bacteriumGO:0096179.8CCR4, CCL2
30G-protein coupled receptor signaling pathwayGO:0071869.8CXCR3, CCL17, CCL2, IL8
31cell adhesionGO:0071559.2CCL11, CCL2, CXCR3, TNC
32immune responseGO:0069559.0CCL17, CCR4, CCL22, CCL11, IL5, IL8
33chemotaxisGO:0069358.9CXCR3, CCL17, CCL2, CCR4, CCL22, CCL11
34inflammatory responseGO:0069548.1CRP, CXCR3, CCL17, CCL2, CCR4, CCL22

Molecular functions related to Pneumonia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1chemokine receptor activityGO:0049509.8CCR4, CXCR3
2cytokine activityGO:0051259.3IFNG, IL5, IL6, IL13
3chemokine activityGO:0080099.1IL8, CCL11, CCL22, CCL2, CCL17

Products for genes affiliated with Pneumonia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
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40NDF-RT
43NINDS
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