MCID: PNM005
MIFTS: 38

Pneumonic Plague malady

Categories: Infectious diseases, Respiratory diseases

Aliases & Classifications for Pneumonic Plague

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Aliases & Descriptions for Pneumonic Plague:

Name: Pneumonic Plague 11 13 68
Secondary Pneumonic Plague 11 68
 
Primary Pneumonic Plague 11 68
Plague 39 68

Classifications:



External Ids:

Disease Ontology11 DOID:10398
ICD1030 A20.2
ICD9CM32 020.3, 020.4, 020.5
MeSH39 D010930

Summaries for Pneumonic Plague

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Disease Ontology:11 A plague that results in infection located in lung, which results from direct inhalation of the bacillus and has symptom fever, has symptom chills, has symptom cough and has symptom difficulty breathing.

MalaCards based summary: Pneumonic Plague, also known as secondary pneumonic plague, is related to plague and bubonic plague, and has symptoms including fever, chills and cough. An important gene associated with Pneumonic Plague is LPP (LIM Domain Containing Preferred Translocation Partner In Lipoma), and among its related pathways are Cell adhesion_Cell-matrix glycoconjugates and Cell adhesion_ECM remodeling. Affiliated tissues include lung, lung and neutrophil, and related mouse phenotypes are homeostasis/metabolism and mortality/aging.

Wikipedia:71 Pneumonic plague, a severe type of lung infection, is one of three main forms of plague, all of which... more...

Related Diseases for Pneumonic Plague

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Diseases related to Pneumonic Plague via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1plague11.8
2bubonic plague9.9
3hepatitis9.8
4leptospirosis9.8
5tuberculosis9.8
6gonococcal seminal vesiculitis7.6AGPS, GAP43, HOXA1, IGFBP7, LPP, PLG

Graphical network of diseases related to Pneumonic Plague:



Diseases related to pneumonic plague

Symptoms & Phenotypes for Pneumonic Plague

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Symptoms:

 11 (show all 4)
  • fever
  • chills
  • cough
  • difficulty breathing

UMLS symptoms related to Pneumonic Plague:


pruritus

MGI Mouse Phenotypes related to Pneumonic Plague according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053768.4AGPS, HOXA1, LPP, PLG, RIMS1, VCAN
2MP:00107687.2AGPS, GAP43, HOXA1, LPP, PLG, RIMS1

Drugs & Therapeutics for Pneumonic Plague

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Drugs for Pneumonic Plague (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Streptomycinapproved, vet_approvedPhase 2, Phase 31957-92-119649
Synonyms:
12672-24-1
2,4-Diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranoside
2-[(1R,2R,3S,4R,5R,6S)-3-(diaminomethylideneamino)-4-[(2R,3R,4R,5S)-3-[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine
2-[(1R,2R,3S,4R,5R,6S)-3-(diaminomethylideneamino)-4-[(2S,3S,4S,5R)-3-[(2R,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine
2-[(1S,2S,3R,4S,5S,6R)-3-(diaminomethylideneamino)-4-[(2R,3R,4R,5S)-3-[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine
2-[(1S,4S)-5-(diaminomethylideneamino)-2-[(2R,5S)-3-[(2S,5R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-3,4,6-trihydroxycyclohexyl]guanidine
3810-74-0
3810-74-0 (sulfate (2:3) salt)
4-18-00-07540 (Beilstein Handbook Reference)
47814-83-5
47816-81-9
57-92-1
82958-69-8
AC1L1LKU
AC1L2EK8
AC1O52TO
AC1O7EO6
AC1Q29OE
ACon1_001297
Agrept
Agrimycin
BPBio1_000355
BRN 0074498
BSPBio_000321
Bio-0644
C00413
C21H39N7O12
CCRIS 5730
CHEBI:17076
CHEBI:405369
CHEMBL1201194
CHEMBL173
CID19649
CID5999
CID6426892
CID6602485
Caswell No. 804
D08531
DB01082
EINECS 200-355-3
EPA Pesticide Chemical Code 006306
Estreptomicina [INN-Spanish]
Gerox
HMS2090P05
HSDB 1768
Hokko-mycin
Kantrex
 
LS-147053
LS-187084
Liposomal Streptomycin
MolPort-002-525-998
N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine
N,N'''-[(1R,2R,3S,4R,5R,6S)-4-{5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyloxy}-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine
NCGC00159339-02
NCGC00179603-01
NCGC00179603-02
NSC 14083
NSC14083
Neodiestreptopab
O-2-Deoxy-2-(methylamino)-.alpha.-L-glucopyranosyl-(1->2)-O-5-deoxy-3-C-formyl-.alpha.-L-lyxofuranosyl-(1->4)-N,N'-bis(aminoiminomethyl)-D-streptamine and Liposome
Prestwick0_000321
Prestwick1_000321
Prestwick2_000321
Prestwick3_000321
SM
SPBio_002242
SRY
STREPTOMYCIN
STREPTOMYCIN SULFATE (2:3) SALT
Strepcen
Streptomicina
Streptomicina [Italian]
Streptomycin & EEP
Streptomycin & Propolis
Streptomycin (INN)
Streptomycin (TN)
Streptomycin A
Streptomycin A sulfate
Streptomycin Sesquisulfate Hydrate
Streptomycin Sesquisulphate Hydrate
Streptomycin Sulfate
Streptomycin Sulphate
Streptomycin [INN:BAN]
Streptomycin a Sulfate
Streptomycin sulfate
Streptomycin sulphate
Streptomycin, Sulfate Salt
Streptomycine
Streptomycinum
Streptomyzin
Streptomyzin [German]
UNII-Y45QSO73OB
[2-Deoxy-2-(dimethylamino)-alpha-L-glucopyranosyl]-(1->2)-[5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl]-(1->4)-{n',n'''-[(1,3,5/2,4,6)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diguanidine}
[2-deoxy-2-(dimethylamino)-alpha-L-glucopyranosyl]-(1->2)-[5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl]-(1->4)-{N',N'''-[(1,3,5/2,4,6)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diguanidine}
streptomycin
2Anti-Infective AgentsPhase 2, Phase 321402
3Anti-Bacterial AgentsPhase 2, Phase 310884
4GentamicinsPhase 2, Phase 3137
5
Doxycyclineapproved, investigational, vet_approvedPhase 2237564-25-054671203
Synonyms:
(2E,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(2Z)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(2Z,4S,4aR,5S,5aR,6R)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione
(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
10597-92-9
17086-28-1 (mono-hydrate)
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6R,12aS)
24390-14-5
41411-66-9 (6-epimer, mono-hydrochloride)
5-Hydroxy-alpha-6-deoxytetracycline
5-hydroxy-╬▒-6-deoxytetracycline
564-25-0
6-Deoxyoxytetracycline
6-Deoxytetracycline
6-alpha-Deoxy-5-oxytetracycline
6-alpha-deoxy-5-oxytetracycline
69935-17-7 (mono-hydrochloride, di-hydrate)
6alpha-Deoxy-5-oxytetracycline
6alpha-deoxy-5-oxytetracycline
6╬▒-deoxy-5-oxytetracycline
7164-70-7
7264-10-0
94088-85-4 (calcium salt (1:2))
AB08 (*Fosfatex)
AC1NQXW7
AC1NS4CW
AC1NUYS8
AC1O8PYM
Alti-Doxycycline
Anhydrous doxycycline
Apo-Doxy
Atridox
Azudoxat
BCBcMAP01_000024
BIDD:GT0146
BMY-28689
BPBio1_000951
BSPBio_000863
BSPBio_001936
BU-3839T
C06973
CHEBI:50845
CHEMBL1433
CID5281011
CID5353597
CID5463943
CID6713981
CPD001550033
D07876
DB00254
DMSC (*Fosfatex)
DOXCYCLINE ANHYDROUS
DOXY
DOXYCYCLINE CALCIUM
DOXYCYCLINE MONOHYDRATE
Deoxymykoin
DivK1c_000345
Dossiciclina
Dossiciclina [DCIT]
Doxcycline anhydrous
Doxiciclina
Doxiciclina [INN-Spanish]
Doxiciclina [Italian]
Doxitard
Doxivetin
Doxy-Caps
Doxy-Puren
Doxy-Tabs
Doxycen
Doxychel
Doxychel (TN)
Doxycin
Doxycyclin
Doxycycline (200mg/day) or Placebo
 
Doxycycline (INN)
Doxycycline (TN)
Doxycycline (anhydrous)
Doxycycline (internal use)
Doxycycline Hyclate
Doxycycline Monohydrate
Doxycycline anhydrous
Doxycycline hyclate
Doxycycline-Chinoin
Doxycyclinum
Doxycyclinum [INN-Latin]
Doxysol
Doxytec
Doxytetracycline
EINECS 209-271-1
GS-3065 (*monohydrate)
HMS2090E06
HSDB 3071
Hydramycin
IDI1_000345
Investin
Jenacyclin
KBio1_000345
KBio2_001287
KBio2_003855
KBio2_006423
KBio3_001156
KBioGR_001133
KBioSS_001287
LS-187766
LS-93868
Liviatin
Lopac0_000405
MolPort-002-507-423
Monodox
Monodox (*monohydrate)
NCGC00161602-01
NCGC00161602-03
NCGC00161602-04
NCGC00167961-01
NCGC00179395-01
NINDS_000345
NSC633557
Novo-Doxylin
Nu-Doxycycline
Oracea
Prestwick0_000852
Prestwick1_000852
Prestwick2_000852
Prestwick3_000852
Ronaxan
SAM002589932
SMP1_000107
SPBio_000246
SPBio_002784
STOCK1N-34341
Spanor
Spectrum2_000143
Spectrum3_000408
Spectrum4_000527
Spectrum5_000947
Spectrum_000807
Supracyclin
UNII-334895S862
UPCMLD-DP021
UPCMLD-DP021:001
Vibra-tabs
Vibramycin
Vibramycin (*monohydrate)
Vibramycin Novum
Vibramycine
Vibravenos
Vivox (*Hyclate)
alpha-6-Deoxy-5-hydroxytetracycline
alpha-6-Deoxyoxytetracycline
alpha-Doxycycline
doxycycline
6
Ciprofloxacinapproved, investigationalPhase 222985721-33-12764
Synonyms:
1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID
1-CYCLOPROPYL-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydroquinoline-3-carboxylic acid
1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperzinyl)-3-quinolinecarboxylic acid HCl H2O
1-Cyclopropyl-6-fluoro-1,4-dihydro-7-(1-piperazinyl)-4-oxo-3-quinoline carboxylic acid
1-Cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid
1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid
1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
1-Cyclopropyl-6-fluoro-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid
1-Cyclopropyl-6-fluoro-7-hexahydro-1-pyrazinyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
1-cyclopropyl-6-fluoro-7-hexahydro-1-pyrazinyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
17850_FLUKA
3-Quinolinecarboxylic acid,1,4-dihydro-1-cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)
33434_FLUKA
33434_RIEDEL
85721-33-1
AC-7613
AC1L1EEW
AKOS000269653
ARONIS020379
Alcon Cilox
BAS 06989041
BAY q 3939
BAY-Q-3939
BAYQ3939
BIDD:GT0205
BPBio1_000140
BRD-K04804440-311-02-3
BRN 3568352
BSPBio_000126
BSPBio_003344
Bacquinor
Baflox
Bay o 9867
Bay o 9867 (*Hydrochloride*)
Bay-09867
Baycip
Bernoflox
Bi-Cipro
Bio-0540
C05349
C17H18FN3O3
CAS-93107-08-5
CBMicro_048498
CCRIS 5241
CHEBI:100241
CHEMBL8
CID2764
CIPRO IN DEXTROSE 5% IN PLASTIC CONTAINER
CIPRO IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
CPF
CPFX
CRL-1605 & Ciprofloxacin
Ciflox
Cifloxin
Cilab
Ciloxan
Ciloxan (*Hydrochloride*)
Ciplus
Ciprecu
Ciprinol
Cipro
Cipro (*Hydrochloride*)
Cipro (TN)
Cipro I.V.
Cipro IV
Cipro XL
Cipro XR
Ciprobay
Ciprobay Uro
Ciprocinol
Ciprodar
Ciproflox
Ciprofloxacin
Ciprofloxacin (JAN/USP/INN)
Ciprofloxacin HCl
Ciprofloxacin Hydrchloride
Ciprofloxacin [USAN:INN:BAN]
Ciprofloxacin dihydrochloride
Ciprofloxacin hydrochloride
Ciprofloxacin monohydrochloride
Ciprofloxacina
Ciprofloxacine
Ciprofloxacine [INN-French]
Ciprofloxacino
 
Ciprofloxacino [INN-Spanish]
Ciprofloxacinum
Ciprofloxacinum [INN-Latin]
Ciprogis
Ciprolin
Ciprolon
Cipromycin
Ciproquinol
Ciprowin
Ciproxan
Ciproxin
Ciproxina
Ciproxine
Ciriax
Citopcin
Cixan
Corsacin
Cycin
Cyprobay
D00186
DB00537
DivK1c_000095
Eni
Fimoflox
Flociprin
Floxin
HMS1922E18
HMS2090O07
HMS2093I03
HMS500E17
HSDB 6987
IDI1_000095
Ipiflox
Italnik
KBio1_000095
KBio2_000642
KBio2_003210
KBio2_005778
KBio3_002846
KBioGR_001567
KBioSS_000642
LS-141563
Liposomal-ciprofloxacin
Loxan
MLS001336035
MolPort-000-819-654
NCGC00016959-01
NCGC00095058-01
NCGC00095058-02
NCGC00178128-01
NINDS_000095
NSC620634
Ocuflox
Oprea1_008239
Oprea1_313572
Prestwick0_000113
Prestwick1_000113
Prestwick2_000113
Prestwick3_000113
Probiox
Proflaxin
Proflox
Proksi 250
Proksi 500
Proquin XR
Quinolid
Quintor
Rancif
Roxytal
SMP1_000125
SMR000471901
SPBio_001474
SPBio_002065
SPECTRUM1503614
STK021082
Septicide
Sophixin Ofteno
Spectrum2_001567
Spectrum3_001872
Spectrum4_000874
Spectrum5_001089
Spectrum_000162
Spitacin
Superocin
UNII-5E8K9I0O4U
Unex
Velomonit
Zumaflox
ciprofloxacin
nchembio820-comp1
7Topoisomerase InhibitorsPhase 24945
8Cytochrome P-450 Enzyme InhibitorsPhase 23822
9Antiprotozoal AgentsPhase 21986
10AntimalarialsPhase 21216
11Antiparasitic AgentsPhase 22127
12Cytochrome P-450 CYP1A2 InhibitorsPhase 2553
13VaccinesPhase 2, Phase 16428

Interventional clinical trials:

idNameStatusNCT IDPhase
1Treatment and Diagnosis of PlagueCompletedNCT00128466Phase 2, Phase 3
2A Clinical Trial to Evaluate the Safety and Efficacy of Ciprofloxacin in the Treatment of Plague in HumansUnknown statusNCT01243437Phase 2
3Immunogenicity and Safety of Subunit Plague VaccineCompletedNCT02596308Phase 2
4Safety, Tolerability & Immunogenicity of the Recombinant Plague Vaccine rF1VCompletedNCT00097396Phase 1

Search NIH Clinical Center for Pneumonic Plague


Cochrane evidence based reviews: plague

Genetic Tests for Pneumonic Plague

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Anatomical Context for Pneumonic Plague

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MalaCards organs/tissues related to Pneumonic Plague:

36
Lung, Neutrophil, Testes, T cells, Spleen

FMA organs/tissues related to Pneumonic Plague:

17
Lung

Publications for Pneumonic Plague

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Articles related to Pneumonic Plague:

(show top 50)    (show all 159)
idTitleAuthorsYear
1
Temporal Progression of Pneumonic Plague in Blood of Nonhuman Primate: A Transcriptomic Analysis. (27003632)
2016
2
Plague in China 2014-All sporadic case report of pneumonic plague. (26895880)
2016
3
New Insights into Autoinducer-2 Signaling as a Virulence Regulator in a Mouse Model of Pneumonic Plague. (27981238)
2016
4
Intranasal delivery of a protein subunit vaccine using a Tobacco Mosaic Virus platform protects against pneumonic plague. (27745954)
2016
5
Plazomicin is effective in a non-human primate pneumonic plague model. (27614915)
2016
6
Correction: Temporal Progression of Pneumonic Plague in Blood of Nonhuman Primate: A Transcriptomic Analysis. (27078634)
2016
7
Host transcriptomic responses to pneumonic plague reveal that Yersinia pestis inhibits both the initial adaptive and innate immune responses in mice. (27876297)
2016
8
Pneumonic Plague: The Darker Side of Yersinia pestis. (26698952)
2016
9
Correction: Yersinia pestis Activates Both IL-1I^ and IL-1 Receptor Antagonist to Modulate Lung Inflammation during Pneumonic Plague. (25970482)
2015
10
Characterization of a Cynomolgus Macaque Model of Pneumonic Plague for Evaluation of Vaccine Efficacy. (26224691)
2015
11
Pneumonic plague outbreak, Northern Madagascar, 2011. (25530466)
2015
12
Primary case of human pneumonic plague occurring in a Himalayan marmot natural focus area Gansu Province, China. (25555623)
2015
13
Combinational Deletion of Three Membrane Protein-Encoding Genes Highly Attenuates Yersinia pestis while Retaining Immunogenicity in a Mouse Model of Pneumonic Plague. (25605764)
2015
14
Controlling Ebola: what we can learn from China's 1911 battle against the pneumonic plague in Manchuria. (25722280)
2015
15
Outbreak of Human Pneumonic Plague with Dog-to-Human and Possible Human-to-Human Transmission--Colorado, June-July 2014. (25928467)
2015
16
Circumventing Y. pestis Virulence by Early Recruitment of Neutrophils to the Lungs during Pneumonic Plague. (25974210)
2015
17
Spatially Distinct Neutrophil Responses within the Inflammatory Lesions of Pneumonic Plague. (26463167)
2015
18
Intramuscular immunization of mice with a live-attenuated triple mutant of Yersinia pestis CO92 induces robust humoral and cell-mediated immunity to completely protect animals against pneumonic plague. (26446423)
2015
19
Yersinia pestis activates both IL-1I^ and IL-1 receptor antagonist to modulate lung inflammation during pneumonic plague. (25781467)
2015
20
Impact of the Pla Protease Substrate I+2-Antiplasmin on the Progression of Primary Pneumonic Plague. (26438794)
2015
21
Efficacy of primate humoral passive transfer in a murine model of pneumonic plague is mouse strain-dependent. (25097863)
2014
22
Remote monitoring of the progression of primary pneumonic plague in Brown Norway rats in high-capacity, high-containment housing. (24719212)
2014
23
LcrV delivered via type III secretion system of live attenuated Yersinia pseudotuberculosis enhances immunogenicity against pneumonic plague. (25114109)
2014
24
Deletion of Braun lipoprotein and plasminogen-activating protease-encoding genes attenuates Yersinia pestis in mouse models of bubonic and pneumonic plague. (24686064)
2014
25
IL-17A Produced by Neutrophils Protects against Pneumonic Plague through Orchestrating IFN-I^-Activated Macrophage Programming. (24337746)
2014
26
Discovery of a leptospirosis cluster amidst a pneumonic plague outbreak in a miners' camp in the Democratic Republic of the Congo. (24514425)
2014
27
Evaluation of imipenem for prophylaxis and therapy of Yersinia pestis delivered by aerosol in a mouse model of pneumonic plague. (24687492)
2014
28
Early host cell targets of Yersinia pestis during primary pneumonic plague. (24098126)
2013
29
A non-invasive in vivo imaging system to study dissemination of bioluminescent Yersinia pestis CO92 in a mouse model of pneumonic plague. (23063826)
2013
30
Early apoptosis of macrophages modulated by injection of Yersinia pestis YopK promotes progression of primary pneumonic plague. (23633954)
2013
31
A cluster of primary pneumonic plague transmitted in a truck cab in a new enzootic focus in China. (23509116)
2013
32
An encapsulated Yersinia pseudotuberculosis is a highly efficient vaccine against pneumonic plague. (22348169)
2012
33
Establishment of a Swiss Webster mouse model of pneumonic plague to meet essential data elements under the animal rule. (22336286)
2012
34
Can sputum collection practices for tuberculosis improve laboratory diagnosis of pneumonic plague in developing countries? (22039916)
2012
35
Phagocytes and humoral immunity to pneumonic plague. (22782760)
2012
36
Transmission dynamics of primary pneumonic plague in the USA. (21733272)
2012
37
Recombinant (F1+V) vaccine protects cynomolgus macaques against pneumonic plague. (21570437)
2011
38
Characterization of an F1 deletion mutant of Yersinia pestis CO92, pathogenic role of F1 antigen in bubonic and pneumonic plague, and evaluation of sensitivity and specificity of F1 antigen capture-based dipsticks. (21367990)
2011
39
Serum cytokine responses in primary pneumonic plague patients. (21106776)
2011
40
Primary pneumonic plague in the African Green monkey as a model for treatment efficacy evaluation. (20722770)
2011
41
Yersinia pestis YopE contains a dominant CD8 T cell epitope that confers protection in a mouse model of pneumonic plague. (21653834)
2011
42
A dog-associated primary pneumonic plague in Qinghai Province, China. (21288842)
2011
43
Intranasal administration of an inactivated Yersinia pestis vaccine with interleukin-12 generates protective immunity against pneumonic plague. (21880856)
2011
44
An individual-based simulation of pneumonic plague transmission following an outbreak and the significance of intervention compliance. (21624780)
2011
45
Cynomolgus macaque model for pneumonic plague. (21040776)
2011
46
Levofloxacin cures experimental pneumonic plague in African green monkeys. (21347450)
2011
47
Lessons learned about pneumonic plague diagnosis from two outbreaks, Democratic Republic of the Congo. (21529384)
2011
48
Prevention of pneumonic plague in mice, rats, guinea pigs and non-human primates with clinical grade rV10, rV10-2 or F1-V vaccines. (21763383)
2011
49
Chemokine receptor CXCR2 mediates bacterial clearance rather than neutrophil recruitment in a murine model of pneumonic plague. (21356370)
2011
50
A comprehensive study on the role of the Yersinia pestis virulence markers in an animal model of pneumonic plague. (21468758)
2011

Variations for Pneumonic Plague

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Expression for genes affiliated with Pneumonic Plague

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Search GEO for disease gene expression data for Pneumonic Plague.

Pathways for genes affiliated with Pneumonic Plague

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Pathways related to Pneumonic Plague according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.6PLG, VCAN
29.6PLG, VCAN
39.5GAP43, VCAN

GO Terms for genes affiliated with Pneumonic Plague

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Biological processes related to Pneumonic Plague according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cell adhesionGO:00071558.8IGFBP7, LPP, VCAN

Molecular functions related to Pneumonic Plague according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:00055156.4AGPS, GAP43, HOXA1, IGFBP7, LPP, PLG

Sources for Pneumonic Plague

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet