MCID: PNM005
MIFTS: 37

Pneumonic Plague malady

Infectious diseases category

Summaries for Pneumonic Plague

About this section
Sources:
8Disease Ontology, 63Wikipedia, 32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Disease Ontology:8 A plague that results in infection located in lung, which results from direct inhalation of the bacillus and has symptom fever, has symptom chills, has symptom cough and has symptom difficulty breathing.

MalaCards: Pneumonic Plague, also known as secondary pneumonic plague, is related to plague and bubonic plague, and has symptoms including fever, chills and cough. An important gene associated with Pneumonic Plague is CHST3 (carbohydrate (chondroitin 6) sulfotransferase 3), and among its related pathways is Toll-Like receptor Signaling Pathways. The compounds n-acetylglucosamine and mannose have been mentioned in the context of this disorder. Affiliated tissues include lung, lung and testes.

Wikipedia:63 Pneumonic plague, is a severe type of lung infection, is one of three main forms of plague, all of which... more...

Aliases & Classifications for Pneumonic Plague

About this section
Sources:
8Disease Ontology, 10DISEASES, 60UMLS, 56SNOMED-CT, 27ICD9CM, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases


Aliases & Descriptions:

pneumonic plague 8 10 60
secondary pneumonic plague 8 60
primary pneumonic plague 8 60
pneumonic plague, unspecified 8


External Ids:

Disease Ontology8 DOID:10398
ICD9CM27 020.3
ICD1025 A20.2

Related Diseases for Pneumonic Plague

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Pneumonic Plague via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1plague11.2
2bubonic plague10.8
3septicemic plague10.1
4hepatitis10.1
5tuberculosis10.1

Graphical network of diseases related to Pneumonic Plague:



Diseases related to pneumonic plague

Clinical Features for Pneumonic Plague

About this section
Sources:
8Disease Ontology
See all sources


Symptoms:

8
  • fever
  • chills
  • cough
  • difficulty breathing

Drugs & Therapeutics for Pneumonic Plague

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Pneumonic Plague

Drug clinical trials:

Search ClinicalTrials for Pneumonic Plague

Search NIH Clinical Center for Pneumonic Plague

Search CenterWatch for Pneumonic Plague

Genetic Tests for Pneumonic Plague

About this section

Anatomical Context for Pneumonic Plague

About this section
Sources:
32MalaCards, 14FMA
See all sources

MalaCards organs/tissues related to Pneumonic Plague:

32
Lung, Testes, T cells, Spleen

FMA organs/tissues related to Pneumonic Plague:

14
Lung

Animal Models for Pneumonic Plague or affiliated genes

About this section

Publications for Pneumonic Plague

About this section
Sources:
50PubMed
See all sources

Articles related to Pneumonic Plague:

(show top 50)    (show all 139)
idTitleAuthorsYear
1
An encapsulated Yersinia pseudotuberculosis is a highly efficient vaccine against pneumonic plague. (22348169)
2012
2
Can sputum collection practices for tuberculosis improve laboratory diagnosis of pneumonic plague in developing countries? (22039916)
2012
3
Transmission dynamics of primary pneumonic plague in the USA. (21733272)
2012
4
A dog-associated primary pneumonic plague in Qinghai Province, China. (21288842)
2011
5
Intranasal administration of an inactivated Yersinia pestis vaccine with interleukin-12 generates protective immunity against pneumonic plague. (21880856)
2011
6
Levofloxacin cures experimental pneumonic plague in African green monkeys. (21347450)
2011
7
Septic shock and nonpulmonary organ dysfunction in pneumonic plague: the role of Yersinia pestis pCD1- vs. pgm- virulence factors. (20400901)
2010
8
How to reduce the impact of "low-risk patients" following a bioterrorist incident: lessons from SARS, anthrax, and pneumonic plague. (20230231)
2010
9
Biosafety level 2 model of pneumonic plague and protection studies with F1 and Psa. (20498260)
2010
10
A parenteral DNA vaccine protects against pneumonic plague. (20197132)
2010
11
Perceptions and reactions with regard to pneumonic plague. (20031056)
2010
12
Characterization of the rat pneumonic plague model: infection kinetics following aerosolization of Yersinia pestis CO92. (19073275)
2009
13
Antibodies and cytokines independently protect against pneumonic plague. (18926869)
2008
14
Lipid A mimetics are potent adjuvants for an intranasal pneumonic plague vaccine. (18722493)
2008
15
Current challenges in the development of vaccines for pneumonic plague. (18324890)
2008
16
Pneumonic plague, northern India, 2002. (17561574)
2007
17
Kinetics of the immune response to the (F1+V) vaccine in models of bubonic and pneumonic plague. (17101198)
2007
18
Oral vaccination with salmonella simultaneously expressing Yersinia pestis F1 and V antigens protects against bubonic and pneumonic plague. (17202369)
2007
19
Comparison of 2 antibiotics that inhibit protein synthesis for the treatment of infection with Yersinia pestis delivered by aerosol in a mouse model of pneumonic plague. (17674322)
2007
20
Respiratory immunity is an important component of protection elicited by subunit vaccination against pneumonic plague. (16377037)
2006
21
Immunogenicity and protective immunity against bubonic plague and pneumonic plague by immunization of mice with the recombinant V10 antigen, a variant of LcrV. (16861680)
2006
22
Plant-made subunit vaccine against pneumonic and bubonic plague is orally immunogenic in mice. (16442673)
2006
23
Protection against bubonic and pneumonic plague with a single dose microencapsulated sub-unit vaccine. (16546306)
2006
24
Progression of primary pneumonic plague: a mouse model of infection, pathology, and bacterial transcriptional activity. (16306265)
2005
25
Structural and functional properties of Yersinia pestis Caf1 capsular antigen and their possible role in fulminant development of primary pneumonic plague. (12645886)
2002
26
A single dose sub-unit vaccine protects against pneumonic plague. (11027822)
2000
27
Intra nasal administration of poly-lactic acid microsphere co-encapsulated Yersinia pestis subunits confers protection from pneumonic plague in the mouse. (9562689)
1998
28
Protection of mice from fatal bubonic and pneumonic plague by passive immunization with monoclonal antibodies against the F1 protein of Yersinia pestis. (9158060)
1997
29
Pathology of experimental pneumonic plague produced by fraction 1-positive and fraction 1-negative Yersinia pestis in African green monkeys (Cercopithecus aethiops). (8712895)
1996
30
Infectivity of pneumonic plague. (7866157)
1995
31
Pneumonic plague in a 15-year-old Utah girl. (8709455)
1995
32
Infectivity of pneumonic plague. (7866091)
1994
33
Cat-transmitted fatal pneumonic plague in a person who traveled from Colorado to Arizona. (8059908)
1994
34
From the Centers for Disease Control. Pneumonic plague--Arizona, 1992. (1404753)
1992
35
Pneumonic plague--Arizona, 1992. (1406565)
1992
36
Possible pneumonic plague. (511127)
1979
37
Unusual manifestation of pneumonic plague. (1253262)
1976
38
Laboratory-acquired pneumonic plague. Report of a case and review of previous cases. (13874924)
1962
39
Pneumonic plague. (14473142)
1961
40
Pneumonic plague in mice: gross and histopathology in untreated and passively immunized animals. (13631290)
1959
41
Pneumonic plague in mice: modification of the infection by antibody against specific components of Pasteurella pestis. (13631291)
1959
42
The development of pneumonic plague in mice and the effect of paralysis of respiratory cilia upon the course of infection. (13439204)
1957
43
Studies on immunization against plague. VIII. Study of three immunizing preparations in protecting primates against pneumonic plague. (14367884)
1955
44
Chronic pneumonic plague in Macaca mulatta. (13207558)
1954
45
Hepatic function and other physiologic studies in monkeys with experimental pneumonic plague. (13212121)
1954
46
Chloramphenicol and terramycin in the treatment of pneumonic plague. (13030486)
1953
47
Antibiotics in the treatment of bubonic and pneumonic plague in man. (13139207)
1952
48
Prophylactic immunization and specific therapy of experimental pneumonic plague. (18913803)
1948
49
Primary pneumonic plague in Mukden, 1946, and report of 39 cases with three recoveries. (18898004)
1948
50
FOUR CASES OF PNEUMONIC PLAGUE. (20765317)
1910

Genetic Variations for Pneumonic Plague

About this section

Expression for genes affiliated with Pneumonic Plague

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Pneumonic Plague

Search GEO for disease gene expression data for Pneumonic Plague.

Pathways for genes affiliated with Pneumonic Plague

About this section
Sources:
52R&D Systems
See all sources

Pathways related to Pneumonic Plague according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.1CLEC4A, PRKCD

Compounds for genes affiliated with Pneumonic Plague

About this section
Sources:
44Novoseek
See all sources

Compounds related to Pneumonic Plague according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1n-acetylglucosamine449.1CLEC4A, CHST3
2mannose449.0LY75, CLEC4A
3galactose448.9CLEC4A, CHST3

GO Terms for genes affiliated with Pneumonic Plague

About this section
Sources:
16Gene Ontology
See all sources

Molecular functions related to Pneumonic Plague according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1carbohydrate bindingGO:0302469.0LY75, CLEC4A

Products for genes affiliated with Pneumonic Plague

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Pneumonic Plague

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet