MCID: PNM008
MIFTS: 50

Pneumothorax malady

Respiratory diseases category
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Summaries for Pneumothorax

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Wikipedia:65 A pneumothorax (pneumo- + thorax; plural pneumothoraces) is an abnormal collection of air or gas in the... more...

MalaCards based summary: Pneumothorax is related to spontaneous pneumothorax and bronchiolitis. An important gene associated with Pneumothorax is FLCN (folliculin), and among its related pathways are Mineral absorption and IL-10 Pathway. The drug talc and the compounds biliverdin and deferoxamine have been mentioned in the context of this disorder. Affiliated tissues include lung, breast and testes, and related mouse phenotypes are immune system and hematopoietic system.

Aliases & Classifications for Pneumothorax

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 62UMLS, 57SNOMED-CT, 27ICD9CM, 34MeSH, 25ICD10
See all sources

Pneumothorax, Aliases & Descriptions:

Name: Pneumothorax 8 10 44 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Respiratory diseases


External Ids:

Disease Ontology8 DOID:1673
ICD9CM27 512.8
MeSH34 D011030
ICD1025 J93, J93.9

Related Diseases for Pneumothorax

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Graphical network of the top 20 diseases related to Pneumothorax:



Diseases related to pneumothorax

Symptoms for Pneumothorax

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Drugs & Therapeutics for Pneumothorax

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Drug clinical trials:

Search ClinicalTrials for Pneumothorax

Search NIH Clinical Center for Pneumothorax

Inferred drug relations via UMLS62/NDF-RT40:

Genetic Tests for Pneumothorax

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Anatomical Context for Pneumothorax

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MalaCards organs/tissues related to Pneumothorax:

32
Lung, Breast, Testes, Kidney, Liver, Colon, Skin, Bone marrow, Bone, Lymph node, Spleen, Spinal cord, Heart, Thyroid

Animal Models for Pneumothorax or affiliated genes

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MGI Mouse Phenotypes related to Pneumothorax:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053878.1HMOX1, CCL11, FLCN, LBP
2MP:00053977.8HMOX1, CCL11, FLCN, LBP

Publications for Pneumothorax

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Articles related to Pneumothorax:

(show top 50)    (show all 1247)
idTitleAuthorsYear
1
Idiopathic pleuroparenchymal fibroelastosis presenting in recurrent pneumothorax: a case report. (25368665)
2014
2
Detection of blebs and bullae in patients with primary spontaneous pneumothorax by multi-detector CT reconstruction using different slice thicknesses. (25196152)
2014
3
Acute respiratory distress syndrome and pneumothorax. (25337400)
2014
4
Minimally invasive thoracoscopic mesh repair of diaphragmatic fenestrations for catamenial pneumothorax due to likely thoracic endometriosis: a case report. (24145272)
2013
5
Treatment of catamenial pneumothorax with absorbable mesh, pleurectomy and pleural abrasion. (23096455)
2013
6
Pneumothorax and cardiac arrest caused by speaking valve mistaken as moisture exchanger: an incident report. (23858073)
2013
7
Anesthesia under cardiopulmonary bypass for video assisted thoracoscopic wedge resection in patient with spontaneous pneumothorax and contralateral post-tuberculosis destroyed lung. (24024004)
2013
8
Core curriculum illustration: pneumothorax. (24203100)
2013
9
Pneumothorax as a complication of lung volume recruitment. (23857693)
2013
10
Sensitivity, positive predictive value, and interobserver variability of computed tomography in the diagnosis of bullae associated with spontaneous pneumothorax in dogs: 19 cases (2003-2012). (23822082)
2013
11
Complete obstruction of an endotracheal tube due to an unexpected blood clot in a patient with a hemo-pneumothorax after repositioning of the patient for lumbar spine surgery. (23646253)
2013
12
Bronchial injury and pneumothorax after reintubation using an airway exchange catheter. (23438805)
2013
13
Detection of pneumothorax with ultrasound. (24133848)
2013
14
A case of adult-onset Still's disease complicated by hemophagocytic syndrome and interstitial pneumonia with pneumomediastinum/recurrent pneumothorax. (22898226)
2012
15
A case of paediatric simulated pneumothorax. (22366040)
2012
16
Non-surgical causes of pneumoperitoneum--characteristic 'Rigler's sign' in a chest x-ray due to pneumothorax with a diaphragmatic hernia. (22718783)
2012
17
Catamenial pneumothorax: a rare entity? Report of 5 cases and review of the literature. (23304438)
2012
18
Facial and upper body papules in a patient with a family history of recurrent pneumothorax. (23268521)
2012
19
Spontaneous tension pneumothorax: what is it and does it exist? (23227475)
2012
20
Pneumothorax, pneumomediastinum, subcutaneous emphysema and pneumorrhachis as complications of common flu. (23569528)
2012
21
Tension pneumothorax at anaesthetic induction in an ex-premature infant with bronchopulmonary dysplasia. (22967679)
2012
22
Pneumothorax post brachial plexus block guided by ultrasound: a case report. (22999407)
2012
23
Bilateral pneumothorax in pregnancy unmasking lymphangioleiomyomatosis. (21076889)
2011
24
Spontaneous pneumothorax and ozone levels: is there a relation? (22958437)
2011
25
Pulmonary synovial sarcoma and pneumothorax. (21263255)
2011
26
Combined spontaneous contralateral pneumothorax and post-pneumonectomy mediastinal shift-associated dextrocardia. (21243579)
2011
27
Surgical tension pneumothorax during laparoscopic repair of massive hiatus hernia: a different situation requiring different management. (22165368)
2011
28
Recurrent spontaneous pneumothorax in a patient with Birt-Hogg-DubAc syndrome. (20692178)
2011
29
Erlotinib treatment for persistent spontaneous pneumothorax in non-small cell lung cancer: a case report. (22166539)
2010
30
Chemotherapy-related delayed bilateral spontaneous pneumothorax and lung fibrosis: methotrexate or cyclophosphamide, or both? (20931743)
2010
31
Decision making in the management of secondary spontaneous pneumothorax in patients with severe emphysema. (19662966)
2009
32
Simultaneous bilateral spontaneous pneumothorax in metastatic testicular cancer. (19140040)
2009
33
Perforated ulcer mimicking a spontaneous pneumothorax in a patient with congenital diaphragmatic hernia. (19385305)
2009
34
Anesthetic management of thoracotomy for spontaneous pneumothorax in a pregnant woman. (17693074)
2008
35
Thoracoscopic apico-posterior transmediastinal approach for bilateral spontaneous pneumothorax. (18187456)
2008
36
Should surgical pleurectomy for spontaneous pneumothorax be always thoracoscopic? (18407960)
2008
37
Ipsilateral reexpansion pulmonary edema after drainage of a spontaneous pneumothorax: a case report. (17903268)
2007
38
Mutations of the Birt Hogg Dube gene in patients with multiple lung cysts and recurrent pneumothorax. (17496196)
2007
39
Use of computed tomography for evaluation of lung lesions associated with spontaneous pneumothorax in dogs: 12 cases (1999-2002). (16506938)
2006
40
Thoracoscopic management of spontaneous pneumothorax during pregnancy. (16165137)
2005
41
Evaluating the treatment options for spontaneous pneumothorax. (15311535)
2004
42
Results of thoracoscopic pleural abrasion for primary spontaneous pneumothorax. (14752638)
2004
43
Catamenial pneumothorax: can all cases be explained by the pore hypothesis? (12907574)
2003
44
Visualization of diaphragmatic fenestration associated with catamenial pneumothorax. (10543524)
1999
45
Expression of CA125 in thoracic endometriosis in a patient with catamenial pneumothorax. (10516547)
1999
46
Diagnosis of pulmonary lymphangioleiomyomatosis by HMB45 in surgically treated spontaneous pneumothorax. (8620956)
1995
47
Pneumothorax and bronchopleural fistula during treatment of allergic bronchopulmonary aspergillosis. (8367756)
1993
48
Value of computed tomography of the lung in the management of primary spontaneous pneumothorax. (2063968)
1991
49
Recurrent spontaneous pneumothorax in diffuse scleroderma. Report of a case. (5907810)
1966
50
Pneumothorax and interstitial emphysema in asthma. (14778095)
1950

Variations for Pneumothorax

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Expression for genes affiliated with Pneumothorax

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Expression patterns in normal tissues for genes affiliated with Pneumothorax

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Pathways for genes affiliated with Pneumothorax

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Pathways related to Pneumothorax according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5HMOX1, FTMT
29.4HMOX1, BLVRA
3
Show member pathways
Transcription NF kB signaling pathway60
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response60
9.0CCL11, LBP
4
Show member pathways
tetrapyrrole biosynthesis37
heme degradation37
Heme Biosynthesis37
heme biosynthesis37
heme biosynthesis from uroporphyrinogen-III I37
9.0HMOX1, FTMT, BLVRA

Compounds for genes affiliated with Pneumothorax

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Sources:
44Novoseek, 24HMDB, 11DrugBank, 50PharmGKB, 28IUPHAR
See all sources

Compounds related to Pneumothorax according to GeneCards/GeneDecks:

(show all 16)
idCompoundScoreTop Affiliating Genes
1biliverdin44 2410.7BLVRA, HMOX1
2deferoxamine44 1110.7HMOX1, FTMT
3Bilirubin249.7BLVRA, HMOX1
4haem449.7HMOX1, BLVRA
515-deoxy-delta-12,14-prostaglandin j2449.5HMOX1, CCL11
6aspirin44 50 28 2412.3HMOX1, CCL11
7cgmp44 2810.2CCL11, HMOX1
8peptidoglycan44 2810.2CCL11, LBP
9heme28 24 1111.1HMOX1, BLVRA
10endotoxin448.9CCL11, FTMT, LBP
11actinomycin d448.7HMOX1, CCL11, LBP
12superoxide44 249.7LBP, CCL11, HMOX1
13dexamethasone44 50 28 1111.6HMOX1, CCL11, LBP
14nitric oxide44 24 1110.6LBP, CCL11, HMOX1
15alanine448.5HMOX1, CCL11, LBP
16oxygen44 248.8HMOX1, CCL11, FTMT, BLVRA, LBP

GO Terms for genes affiliated with Pneumothorax

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Cellular components related to Pneumothorax according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056158.5HMOX1, CCL11, LBP

Biological processes related to Pneumothorax according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1heme catabolic processGO:0421679.4HMOX1, BLVRA
2porphyrin-containing compound metabolic processGO:0067789.3HMOX1, BLVRA
3positive regulation of angiogenesisGO:0457669.3HMOX1, CCL11
4cellular iron ion homeostasisGO:0068799.2HMOX1, FTMT

Products for genes affiliated with Pneumothorax

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Sources for Pneumothorax

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet