Aliases & Classifications for Podoconiosis

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Aliases & Descriptions for Podoconiosis:

Name: Podoconiosis 49 10 12 65
 
Podoconiosis, Susceptibility to 11

Classifications:



External Ids:

OMIM49 614590
Disease Ontology10 DOID:0050138
UMLS65 C1280469

Summaries for Podoconiosis

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OMIM:49 Podoconiosis, or endemic nonfilarial elephantiasis, is a noninfectious geochemical disease characterized by edema of... (614590) more...

MalaCards based summary: Podoconiosis, also known as podoconiosis, susceptibility to, is related to leukemia and lung cancer. An important gene associated with Podoconiosis is PDCOS (Podoconiosis, Susceptibility To), and among its related pathways are Syndecan-1-mediated signaling events and Cell adhesion molecules (CAMs). Affiliated tissues include lung, small intestine and liver, and related mouse phenotype integument.

Wikipedia:68 Podoconiosis, also known as nonfilarial elephantiasis, is a disease of the lymph vessels of the lower... more...

Related Diseases for Podoconiosis

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Graphical network of the top 20 diseases related to Podoconiosis:



Diseases related to podoconiosis

Symptoms for Podoconiosis

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Clinical features from OMIM:

614590

Drugs & Therapeutics for Podoconiosis

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Promoting Consistent Shoe Use Among Children At High Risk for PodoconiosisCompletedNCT01160523
2Genetic and Other Aspects of PodoconiosisNot yet recruitingNCT01939431

Search NIH Clinical Center for Podoconiosis

Genetic Tests for Podoconiosis

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Anatomical Context for Podoconiosis

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MalaCards organs/tissues related to Podoconiosis:

33
Lung, Small intestine, Liver, T cells, Myeloid, Skin, Breast

Animal Models for Podoconiosis or affiliated genes

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MGI Mouse Phenotypes related to Podoconiosis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107717.4CDKAL1, PDPN, PPARA, SDC1, SLC24A5, TGFB1

Publications for Podoconiosis

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Articles related to Podoconiosis:

(show top 50)    (show all 68)
idTitleAuthorsYear
1
Genome-wide miR-155 and miR-802 target gene identification in the hippocampus of Ts65Dn Down syndrome mouse model by miRNA sponges. (26546125)
2015
2
Reduction in the length of stay with rivaroxaban as a single-drug regimen for the treatment of deep vein thrombosis and pulmonary embolism. (24432872)
2014
3
Treatment of intracranial vasospasm following subarachnoid hemorrhage. (24904517)
2014
4
Reducing TNF Receptor 2+ Regulatory T Cells via the Combined Action of Azacitidine and the HDAC Inhibitor, Panobinostat for Clinical Benefit in Acute Myeloid Leukemia Patients. (24297862)
2014
5
Inflammatory Bowel Disease in Glycogen Storage Disease Type Ia: A Case Series. (25304890)
2014
6
A combined effect of two Alzheimer's risk genes on medial temporal activity during executive attention in young adults. (24388797)
2014
7
Safety and Therapeutic Efficacy of Complete or Near-Complete Ablation of Symptomatic Uterine Fibroid Tumors by MR Imaging-Guided High-Intensity Focused US Therapy. (24360886)
2014
8
Phase I trial of fenretinide delivered orally in a novel organized lipid complex in patients with relapsed/refractory neuroblastoma: a report from the New Approaches to Neuroblastoma Therapy (NANT) consortium. (23813912)
2013
9
Post-fever retinitis: a single center experience from south India. (24362635)
2013
10
Molecular study of a Hoxa2 gain-of-function in chondrogenesis: a model of idiopathic proportionate short stature. (24129174)
2013
11
Comparison of High Frequency Positive Pressure Mechanical Ventilation (HFPPV) With Conventional Method in the Treatment of Neonatal Respiratory Failure. (23983995)
2013
12
The non-transplant treatment of myelodysplastic syndromes-what's on the horizon? (23079065)
2012
13
A 48-year-old woman with a new diagnosis of autoimmune hepatitis. (22610007)
2012
14
Eyelid metastasis as an initial presentation of a gastric adenocarcinoma. (20633788)
2010
15
Canadian kidney cancer forum 2008. (18682767)
2008
16
Tolerability of oral ziprasidone in children and adolescents with bipolar mania, schizophrenia, or schizoaffective disorder. (18928413)
2008
17
Skeletal and cardiac myopathy in HIV-1 transgenic rats. (18713959)
2008
18
Insulin sensitivity, adjusted beta-cell function and adiponectinaemia among lean drug-naive schizophrenic patients treated with atypical antipsychotic drugs: a nine-month prospective study. (18693056)
2008
19
Oxidative stress kills human primary oligodendrocytes via neutral sphingomyelinase: implications for multiple sclerosis. (18040843)
2007
20
Reversal of mirror syndrome after prenatal treatment of Diamond-Blackfan anemia. (17828794)
2007
21
Structural analysis of four and half LIM protein-2 in dilated cardiomyopathy. (17416352)
2007
22
Mature teratoma presenting as a scalp mass in a newborn. (17003635)
2006
23
Unexpected role of TRPC6 channel in familial nephrotic syndrome: does it have clinical implications? (16396961)
2006
24
Epirubicin glucuronidation and UGT2B7 developmental expression. (16985101)
2006
25
Reduced affinity to and inhibition by DKK1 form a common mechanism by which high bone mass-associated missense mutations in LRP5 affect canonical Wnt signaling. (15923613)
2005
26
Synthesis and aminoacyl-tRNA synthetase inhibitory activity of aspartyl adenylate analogs. (15582453)
2005
27
Abl-kinase-sensitive levels of ERK5 and its intrinsic basal activity contribute to leukaemia cell survival. (15608616)
2005
28
Histone deacetylases inhibition and tumor cells cytotoxicity by CNS-active VPA constitutional isomers and derivatives. (15857614)
2005
29
Artifactual hyperbilirubinemia due to paraprotein interference. (12521367)
2003
30
Poly(A)-binding protein interaction with elF4G stimulates picornavirus IRES-dependent translation. (11780631)
2001
31
Upc2p and Ecm22p, dual regulators of sterol biosynthesis in Saccharomyces cerevisiae. (11533229)
2001
32
Radioimmunoassay for N-terminal probrain natriuretic peptide in human plasma. (11300609)
2001
33
Antisense anti-MDM2 oligonucleotides as a novel therapeutic approach to human breast cancer: in vitro and in vivo activities and mechanisms. (11705884)
2001
34
Overexpression of acid ceramidase protects from tumor necrosis factor-induced cell death. (10974027)
2000
35
Induction of melanocyte-specific microphthalmia-associated transcription factor by Wnt-3a. (10747853)
2000
36
Changes in serum cartilage marker levels indicate altered cartilage metabolism in families with the osteoarthritis-related type II collagen gene COL2A1 mutation. (9920012)
1999
37
A continuous method for enzymatic assay of sucrose synthase in the synthetic direction. (10552558)
1999
38
Complement system in healthy term newborns: reference values in umbilical cord blood. (9507037)
1998
39
A case of lymphoid interstitial pneumonia in a 3-month-old boy not associated with HIV infection: immunohistochemistry of lung biopsy specimens and serum transforming growth factor-beta 1 assay. (9361104)
1997
40
Relationship between endometrial oxytocin receptors and oxytocin-induced prostaglandin F2 alpha release during the oestrous cycle and early pregnancy in pony mares. (9068425)
1997
41
Nesidioblastosis in an adult with hyperinsulinemic hypoglycemia. (8793331)
1996
42
The calcitonin-calcium relation curve and calcitonin secretory parameters in renal patients with variable degrees of renal function. (8808222)
1995
43
Changes in serum eosinophil cation protein level and blood eosinophil density in patients with asthma]. (8731855)
1995
44
Motion sickness. (7794234)
1995
45
The action of interleukin-2 receptor subunits defines a new type of signaling mechanism for hematopoietin receptors in hepatic cells and fibroblasts. (7713938)
1995
46
Tumor-antigen 4. Its immunohistochemical distribution and tissue and serum concentrations in squamous cell carcinoma of the lung and esophagus. (2208001)
1990
47
Acute myelomonocytic leukemia with neurologic manifestations in the dog. (3457488)
1986
48
Regional chromosome mapping of human collagen genes alpha 2(I) and alpha 1(I) (COLIA2 and COLIA1). (3857213)
1985
49
Exencephaly and axial skeletal dysmorphogenesis induced by acute doses of ethanol in mouse fetuses. (4092608)
1985
50
INTESTINAL MOTILITY IN MAN. II. THE BEHAVIOR OF THE SMALL INTESTINE FOLLOWING PARTIAL GASTRECTOMY WITH PARTICULAR REFERENCE TO THE DUMPING SYNDROME. (14252754)
1965

Variations for Podoconiosis

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Expression for genes affiliated with Podoconiosis

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Search GEO for disease gene expression data for Podoconiosis.

Pathways for genes affiliated with Podoconiosis

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Pathways related to Podoconiosis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.1SDC1, TGFB1
29.0HLA-DQA1, NEGR1, SDC1
38.7HBA1, SDC1, TGFB1

GO Terms for genes affiliated with Podoconiosis

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Cellular components related to Podoconiosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1endosome membraneGO:00100089.7CD68, HLA-DQA1

Biological processes related to Podoconiosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1wound healingGO:00420609.4PPARA, SDC1
2lipoprotein metabolic processGO:00421579.2PPARA, SDC1
3response to organic substanceGO:00100339.1SDC1, TGFB1

Sources for Podoconiosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet