MCID: PMS001
MIFTS: 55

Poems Syndrome malady

Categories: Rare diseases, Neuronal diseases, Blood diseases, Immune diseases, Skin diseases, Bone diseases

Aliases & Classifications for Poems Syndrome

About this section
Sources:
11Disease Ontology, 13DISEASES, 30ICD10 via Orphanet, 38MeSH, 39MESH via Orphanet, 44NCIt, 47NIH Rare Diseases, 49Novoseek, 53Orphanet, 61SNOMED-CT, 67UMLS, 68UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Poems Syndrome:

Name: Poems Syndrome 11 47 53 49 38 13 67
Osteosclerotic Myeloma 53 67
Crow-Fukase Syndrome 47 53
Polyneuropathy, Organomegaly, Endocrinopathy, M Protein, and Skin Changes Syndrome 47
 
Polyneuropathy-Endocrinopathy-Plasma Cell Dyscrasia Syndrome 53
Polyneuropathy Organomegaly 47
Takatsuki Syndrome 53
Pep Syndrome 53

Characteristics:

Orphanet epidemiological data:

53
poems syndrome:
Age of onset: Adult,Elderly; Age of death: adult,elderly,normal life expectancy

Classifications:



External Ids:

Disease Ontology11 DOID:14039
MeSH38 D016878
NCIt44 C80303
Orphanet53 ORPHA2905
SNOMED-CT61 79268002
MESH via Orphanet39 D016878
UMLS via Orphanet68 C0085404, C1510415
ICD10 via Orphanet30 D47.7

Summaries for Poems Syndrome

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Wikipedia:70 POEMS syndrome (also known as Crow–Fukase syndrome, Takatsuki disease, or PEP syndrome) is a rare... more...

MalaCards based summary: Poems Syndrome, also known as osteosclerotic myeloma, is related to pulmonary hypertension and alopecia, and has symptoms including decreased nerve conduction velocity, anterior hypopituitarism and thickened skin. An important gene associated with Poems Syndrome is VEGFA (Vascular Endothelial Growth Factor A), and among its related pathways are Prion diseases and IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types. Affiliated tissues include skin, endothelial and bone, and related mouse phenotypes are neoplasm and skeleton.

Related Diseases for Poems Syndrome

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Diseases related to Poems Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 356)
idRelated DiseaseScoreTop Affiliating Genes
1pulmonary hypertension30.5IL1B, TNF
2alopecia29.7IL6, TNF
3cryoglobulinemia29.5IL1B, IL6, TNF
4sinusitis29.4IL1B, TNF
5myocardial infarction28.9IL1B, IL6, TNF, VEGFA
6lateral sclerosis28.7IL1B, IL6, TNF, VEGFA
7rheumatoid arthritis28.7IL1B, IL6, TNF, VEGFA
8kidney sarcoma10.5IL6, VEGFA
9amelogenesis imperfecta hypomaturation type10.5IL6, VEGFA
10labia minora cancer10.5IL6, VEGFA
11cyclothymic disorder10.5IL6, VEGFA
12histoplasmosis10.5IL6, VEGFA
13hereditary renal cell carcinoma10.5IL6, VEGFA
14marchiafava bignami disease10.5IL6, VEGFA
15thrombophilia10.5IL6, VEGFA
16corneal deposit10.4IL1B, IL6
17tarsal tunnel syndrome10.4IL1B, IL6
18midline interhemispheric variant of holoprosencephaly10.4IL1B, IL6
19hemoglobinopathy10.4IL1B, IL6
20melorheostosis10.4IL1B, IL6
21infancy electroclinical syndrome10.4IL1B, IL6
22cutaneous liposarcoma10.4MYOM2, VEGFA
23conventional leiomyosarcoma10.4IL1B, IL6
24spinal cord astrocytoma10.4MYOM2, VEGFA
25colorectal adenoma10.4FGF2, VEGFA
26subglottis neoplasm10.4IL1B, IL6
27lung occult adenocarcinoma10.4IL1B, IL6
28sacrococcygeal teratoma10.4IL6, VEGFA
29inflammatory spondylopathy10.4IL1B, IL6
30syphilitic encephalitis10.4IL1B, IL6
31enamel erosion10.4FGF2, VEGFA
32ocular cancer10.4IL1B, IL6
33silver-russell syndrome due to 7p11.2p13 microduplication10.4FGF2, IL1B
34periodic paralyses10.4IL1B, IL6
35human monocytic ehrlichiosis10.4IL1B, IL6
36philophthalmiasis10.4IL1B, IL6
37solitary osseous plasmacytoma10.4IL6, MYOM2
38ulcerative colitis10.4IL1B, IL6
39renal artery disease10.4IL1B, IL6
40ischemic heart disease10.4IL6, VEGFA
41gastric small cell carcinoma10.4FGF2, VEGFA
42postural hypotension10.4FGF2, VEGFA
43bullous pemphigoid10.4IL6, MYOM2
44echinococcosis10.4IL1B, IL6
45vitreous abscess10.4FGF2, VEGFA
46polyneuropathy10.4
47cerebellopontine angle primitive neuroectodermal10.3FGF2, IL6
48neurofibroma of the esophagus10.3IL6, MYOM2
49tollner horst manzke syndrome10.3FGF2, VEGFA
50epidural abscess10.3FGF2, VEGFA

Graphical network of the top 20 diseases related to Poems Syndrome:



Diseases related to poems syndrome

Symptoms for Poems Syndrome

About this section

Human phenotypes related to Poems Syndrome:

 63 (show all 20)
id Description HPO Frequency HPO Source Accession
1 decreased nerve conduction velocity63 hallmark (90%) HP:0000762
2 anterior hypopituitarism63 hallmark (90%) HP:0000830
3 thickened skin63 hallmark (90%) HP:0001072
4 splenomegaly63 hallmark (90%) HP:0001744
5 hepatomegaly63 hallmark (90%) HP:0002240
6 lymphadenopathy63 hallmark (90%) HP:0002716
7 decreased antibody level in blood63 hallmark (90%) HP:0004313
8 irregular hyperpigmentation63 hallmark (90%) HP:0007400
9 gynecomastia63 typical (50%) HP:0000771
10 hypothyroidism63 typical (50%) HP:0000821
11 secondary amenorrhea63 typical (50%) HP:0000869
12 hypertrichosis63 typical (50%) HP:0000998
13 lymphedema63 typical (50%) HP:0001004
14 type ii diabetes mellitus63 typical (50%) HP:0005978
15 neoplasm of the skeletal system63 typical (50%) HP:0010622
16 increased bone mineral density63 typical (50%) HP:0011001
17 arteriovenous malformation63 typical (50%) HP:0100026
18 nephropathy63 occasional (7.5%) HP:0000112
19 tapered finger63 occasional (7.5%) HP:0001182
20 primary adrenal insufficiency63 occasional (7.5%) HP:0008207

Drugs & Therapeutics for Poems Syndrome

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Drugs for Poems Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 41)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
LenalidomideapprovedPhase 2718191732-72-6216326
Synonyms:
1-oxo-2-(2,6-Dioxopiperidin-3-yl)-4-aminoisoindoline
191732-72-6
3-(4-Amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione
3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione
3-(7-Amino-3-oxo-1H-isoindol-2-yl)-piperidine-2,6-dione
3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione
346670-73-3
443912-14-9
AC-914
AC1L50II
AKOS005146276
ALBB-015321
Bio-0168
C467567
CC 5013
CC-5013
CC-5013, Revlimid, Lenalidomide
CC5013
CDC 501
CDC-501
CDC-5013
CHEMBL848
CID216326
Celgene brand of lenalidomide
D04687
 
DB00480
EC-000.2340
ENMD-0997
I06-0831
IMID-1
IMID-5013
IMiD3
IMiD3 cpd
IMid-1
LS-184040
Lenalidomide
Lenalidomide (USAN/INN)
Lenalidomide [USAN]
MolPort-003-848-370
NCGC00167491-01
NSC747972
Revamid
Revimid
Revlimid
Revlimid (Celgene)
Revlimid (TN)
S1029_Selleck
STK639603
Thalidomide analog CC-5013
UNII-F0P408N6V4
lenalidomide
2
Dexamethasoneapproved, investigational, vet_approvedPhase 2208450-02-25743
Synonyms:
(3H)-Dexamethasone
.delta.(sup 1)-9-.alpha.-Fluoro-16-.alpha.-methylcortisol
.gamma.corten
1-Dehydro-16.alpha.-methyl-9.alpha.-fluorohydrocortisone
1-Dehydro-16alpha -methyl-9alpha -fluorohydrocortisone
1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone
1-Dehydro-16α-methyl-9α-fluorohydrocortisone
137098-19-2
16-alpha-Methyl-9-alpha-fluoro-1-dehydrocortisol
16-alpha-Methyl-9-alpha-fluoro-delta(sup 1)-hydrocortisone
16-alpha-Methyl-9-alpha-fluoro-delta1-hydrocortisone
16-alpha-Methyl-9-alpha-fluoroprednisolone
16.alpha.-Methyl-9.alpha.-fluoro-1-dehydrocortisol
16.alpha.-Methyl-9.alpha.-fluoroprednisolone
16alpha -Methyl-9alpha -fluoro-1-dehydrocortisol
16alpha -Methyl-9alpha -fluoroprednisolone
16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol
16alpha-Methyl-9alpha-fluoro-delta(sup 1)-hydrocortisone
16alpha-Methyl-9alpha-fluoroprednisolone
16α-Methyl-9α-fluoro-1-dehydrocortisol
23495-06-9
31375_FLUKA
46165_FLUKA
46165_RIEDEL
50-02-2
8054-59-9
9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11alpha -methylpregna-1,4-diene-3,20-dione
9-Fluoro-16-methylprednisolone
9-alpha-Fluoro-16-alpha-methylprednisolone
9.alpha.-Fluoro-16.alpha.-methylprednisolone
906422-84-2
9A-FLUORO-16BETA-METHYLPREDNISOLONE
9alpha -Fluoro-16alpha -methylprednisolone
9alpha-Fluoro-16alpha-methylprednisolone
9alpha-fluoro-16alpha-methyl-Prednisolone
9α-Fluoro-16α-methylprednisolone
AC-11056
AC1L1L1H
AC1Q29DM
AI3-50934
Adexone
Aeroseb-D
Aeroseb-Dex
Aeroseb-dex
Ak Dex Oph Otic Soln 0.1%
Alcon Brand of Dexamethasone
Anaflogistico
Aphtasolon
Aphthasolone
Apo-dexamethasone
Auxiron
Azimycin (veterinary)
Azium
Azium (Veterinary)
Azium (veterinary)
BIDD:ER0494
BIDD:PXR0060
BRD-K38775274-001-02-3
BRD-K38775274-001-06-4
BSPBio_000995
Bisu DS
Bisu Ds
C15643
C22H29FO5
CCRIS 7067
CHEBI:41879
CHEMBL384467
CID5743
CPD-10549
CPD001227192
Calonat
Corson
Corsone
Cortisumman
D00292
D003907
D1756_SIGMA
D4902_SIGMA
D6645_SIGMA
D8893_SIGMA
D9184_SIGMA
DB01234
DEX
DEXA
DEXONE 0.5
DEXONE 0.75
DEXONE 1.5
DEXONE 4
DXM
DXMS
Decacort
Decacortin
Decaderm
Decadron
Decadron (TN)
Decadron Tablets, Elixir
Decadron, Dexamethasone
Decadron-LA
Decadron-La
Decagel
Decaject
Decaject L.A.
Decaject-L.A.
Decalix
Decameth
Decasone
Decaspray
Dectancyl
Dekacort
Delta1-9alpha-Fluoro-16alpha-methylcortisol
Deltafluorene
Dergramin
Deronil
Desadrene
Desametasone
Desametasone [DCIT]
Desametasone [Dcit]
Desamethasone
Desameton
Deseronil
Dex-Ide
Dex-ide
Dexa
Dexa Mamallet
Dexa mamallet
Dexa-Cortidelt
Dexa-Cortisyl
Dexa-Mamallet
Dexa-Scheroson
Dexa-Sine
Dexa-cortidelt
Dexa-cortisyl
Dexa-scheroson
Dexa-sine
Dexacen-4
Dexacidin
Dexacort
Dexacortal
Dexacortin
Dexadeltone
Dexafarma
Dexair
Dexalona
Dexaltin
Dexametasona
Dexametasona [INN-Spanish]
Dexametasone
 
Dexameth
Dexamethansone
Dexamethasone
Dexamethasone (JP15/USP/INN)
Dexamethasone Acetate
Dexamethasone Alcohol
Dexamethasone Base
Dexamethasone Intensol
Dexamethasone Sodium Phosphate
Dexamethasone [INN:BAN:JAN]
Dexamethasone alcohol
Dexamethasone base
Dexamethasone intensol
Dexamethasone-omega
Dexamethasonum
Dexamethasonum [INN-Latin]
Dexamethazone
Dexamonozon
Dexapolcort
Dexapos
Dexaprol
Dexason
Dexasone
Dexasone 0.5mg
Dexasone 0.75mg
Dexasone 4mg
Dexasporin
Dexinolon
Dexinoral
Dexone
Dexone 0.5
Dexone 0.75
Dexone 1.5
Dexone 4
Dexonium
Dexpak
Dextelan
Dezone
Dinormon
Dxms
ECR Brand of Dexamethasone
EINECS 200-003-9
FT-0080377
Fluormethylprednisolone
Fluormone
Fluorocort
Fortecortin
Foy Brand of Dexamethasone
Gammacorten
HL-dex
HMS1792A17
HMS1990A17
HMS2089N13
HSDB 3053
Hexadecadrol
Hexadrol
Hexadrol Elixir
Hexadrol Tablets
Hexadrol elixir
Hl-Dex
Hl-dex
I06-1196
ICN Brand of Dexamethasone
IontoDex
Isopto-Dex
Isopto-dex
LS-7300
Lokalison F
Lokalison f
Loverine
Luxazone
MK 125
MLS001055412
MLS001332507
MLS001332508
Maxidex
Maxidex Ont 0.1%
Maxidex Sus 0.1%
Maxitrol
Mediamethasone
Merck Brand of Dexamethasone
Merz Brand 1 of Dexamethasone
Merz Brand 2 of Dexamethasone
Methylfluorprednisolone
Mexidex
Millicorten
MolMap_000018
MolPort-003-846-433
Mymethasone
NCGC00091019-01
NCGC00091019-02
NCGC00091019-03
NCGC00091019-04
NCGC00091019-05
NCI60_003067
NSC 34521
NSC34521
Naquasone (veterinary)
Neomycin and polymyxin b sulfates and dexamethasone
Neomycin and polymyxin b sulphates and dexamethasone
OTO-104
Ocu-Trol
Ocu-trol
Oradexon
PHL-dexamethasone
PMS-dexamethasone
Pet Derm III
Pet Derm Iii
Pet derm III
Pet-Derm Iii
Pms Dexamethasone Elixir 0.5mg/5ml
Policort
Posurdex
Prednisolon F
Prednisolon f
Prednisolone F
Prednisolone f
Prodex
S1322_Selleck
SAM002548948
SGCUT00126
SK-Dexamethasone
SK-dexamethasone
SMP1_000092
SMR000857119
SMR001227192
ST50307091
Sandoz dexamethasone
Sk-Dexamethasone
Spectrum5_002019
Spoloven
Sunia Sol D
Sunia sol D
Superprednol
TL8003317
Tobradex
Tobramycin and dexamethasone
Tresaderm (veterinary)
Turbinaire
UNII-7S5I7G3JQL
Visumetazone
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ G1
ZINC03875332
alpha -Fluoro-16-alpha -methylcortisol
delta(Sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta(sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta1-9alpha-Fluoro-16alpha-methylcortisol
dexamethasone
nchembio809-comp2
to_000038
3
Pioglitazoneapproved, investigationalPhase 2435111025-46-84829
Synonyms:
(+-)-5-((4-(2-(5-Ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione
(+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione
(+/-)-5-[[4-[2-(5-Ethyl-2-pyridinyl)-ethoxy]phenyl]methyl]-2,4-thiazolidinedione
(+/-)-5-[p-[2-(ethyl-2-pyridyl)ethoxy]benzyl]-2,4-thiazolidinedione
105355-27-9
111025-46-8
198077-89-3
2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]- (9CI)
5-((4-(2-(5-Ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione
5-(4-(2-(5-ethyl-2-pyridyl)ethoxy)benzyl)-2,4-thiazolidinedione
5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl]thiazolidine-2,4-dione
5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione
5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]thiazolidine-2,4-dione
5-[[4-[2-[(5-ethyl-2-pyridyl)]ethoxy]phenyl]methyl]thiazolidine- 2,4-dione
5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione
AB1004597
AC-1021
AC1L1J1Q
AD 4833
AD-4833
Actos
Actos (TN)
Actost
BRD-A48430263-003-02-4
BSPBio_002723
C07675
C19H20N2O3S
CHEBI:8228
CHEMBL595
CID4829
D08378
DB01132
Duetact
Glustin
HMS2089H14
HS-0047
 
HSDB 7322
I06-0089
KBio2_002103
KBio2_004671
KBio2_007239
KBio3_001943
KBioGR_001619
KBioSS_002103
LS-151327
MolPort-002-508-211
NCGC00163128-01
NCGC00163128-02
Pioglitazona
Pioglitazona [INN-Spanish]
Pioglitazone
Pioglitazone HCl
Pioglitazone Hydrochloride
Pioglitazone [BAN:INN]
Pioglitazone [Ban:Inn]
Pioglitazone [INN:BAN]
Pioglitazonum
Pioglitazonum [INN-Latin]
SPBio_001897
Spectrum2_001679
Spectrum3_001002
Spectrum4_001130
Spectrum5_001480
Spectrum5_002067
Spectrum_001623
U 72107
U 72107A
U-72107
U72,107A
UNII-X4OV71U42S
Zactos
nchembio790-comp10
pioglitazone (INN)
pioglitazone HCl
4Hormone AntagonistsPhase 212778
5HIV Protease InhibitorsPhase 25319
6glucocorticoidsPhase 24920
7HormonesPhase 213979
8Immunosuppressive AgentsPhase 212770
9
protease inhibitorsPhase 25320
Synonyms:
 
protease inhibitors
10Angiogenesis InhibitorsPhase 24143
11Gastrointestinal AgentsPhase 28109
12Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 212767
13Peripheral Nervous System AgentsPhase 222776
14Anti-Infective AgentsPhase 221402
15Anti-Bacterial AgentsPhase 210884
16Angiogenesis Modulating AgentsPhase 24072
17Dexamethasone acetatePhase 220841177-87-3
18Anti-Inflammatory AgentsPhase 210355
19AntiemeticsPhase 23888
20Antineoplastic Agents, HormonalPhase 25407
21BB 1101Phase 22084
22Autonomic AgentsPhase 29774
23Dexamethasone 21-phosphatePhase 22084
24Insulin, Globin ZincPhase 24523
25insulinPhase 24524
26Hypoglycemic AgentsPhase 25733
27Ixazomibapproved811072833-77-2
28
Maravirocapproved, investigational142376348-65-13002977
Synonyms:
376348-65-1
4,4-Difluoro-N-((1S)-3-(exo-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo(3.2.1)oct-8-yl)-1-phenylpropyl)cyclohexanecarboxamide
4,4-difluoro-N-[(1S)-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]cyclohexane-1-carboxamide
674782-29-7
AC-558
AC1MHEFQ
CHEBI:537583
CHEMBL1201187
CHEMBL256907
CID3002977
Celsentri
Celsentri(TM)
DB04835
Isopropyl, 4,4-difluoro-N-((1S)-3-{(1R,3s,5S)-3-(3-methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl)-8-azabicyclo(3.2.1)octan-8-yl}-1-phenylpropyl)cyclohexanecarboxamide
 
LS-182818
MVC
Maraviroc
Maraviroc [USAN]
PRO 140 & Maraviroc
PRO 140 (Anti-CCR5 monoclonal antibody) & exo-4,4-Difluoro-N-[3-[3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl]-1(S)-phenylpropyl]cyclohexanecarboxamide
Selzentry
Selzentry(TM)
UK 427857
UK-427,857
UK-427,857 maraviroc (MVC)
UK-427857
UNII-MD6P741W8A
exo-4,4-Difluoro-N-[3-[3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl]-1(S)-phenylpropyl]cyclohexanecarboxamide
maraviroc
29
Glycineapproved, nutraceutical, vet_approved22656-40-6750
Synonyms:
(1-13c)glycinato
(15N)Glycine
15527_RIEDEL
15527_SIAL
15743-44-9 (mono-potassium salt)
17829-66-2 (cobalt salt)
18875-39-3
2,2-dialkylglycines
2-Aminoacetate
2-Aminoacetic acid
2311-65-1
25718-94-9
29728-27-6 (monoammonium salt)
32817-15-5 (copper salt)
33226_RIEDEL
33226_SIAL
33242-26-1 (calcium salt)
35947-07-0 (calcium salt (2:1))
410225_SIAL
50046_FLUKA
50046_SIGMA
513-29-1 (sulfate (3:1))
52955-63-2
56-40-6
57678-19-0
6000-43-7 (hydrochloride)
6000-44-8 (mono-hydrochloride salt)
63183-41-5 (hydrochloride hydrogen carbonate)
71295-98-2 (phosphate (1:1))
7490-95-1 (hydrochloride (2:1)
7490-95-1 (hydrochloride (2:1))
7575-55-5
848646-45-7
87867-94-5
AB-131/40217813
AB1002628
AC1L19XW
AC1Q28JW
AC1Q53O0
AI3-04085
AKOS000119626
AMINOACETIC ACID 1.5% IN PLASTIC CONTAINER
AR-1A0345
AR-1A0532
Acide aminoacetique
Acide aminoacetique [INN-French]
Acido aminoacetico
Acido aminoacetico [INN-Spanish]
Acidum aminoaceticum
Acidum aminoaceticum [INN-Latin]
Aciport
Amino-Acetate
Amino-Acetic acid
Aminoacetate
Aminoacetic acid
Aminoazijnzuur
Aminoessigsaeure
Aminoethanoate
Aminoethanoic acid
Amitone
B72BA06C-60E9-4A83-A24A-A2D7F465BB65
BPBio1_001222
Biomol-NT_000195
C00037
CCRIS 5915
CHEBI:15428
CHEBI:15705
CHEBI:16228
CHEMBL773
CID750
CPD-8569
Corilin
D00011
DB00145
EINECS 200-272-2
 
FEMA No. 3287
FT-0083159
G
G0099
G0317
G5417_SIGMA
G5523_SIGMA
G7126_SIGMA
G7403_SIGMA
G8790_SIGMA
G8898_SIGMA
GLY (IUPAC abbrev)
GLYCINE 1.5% IN PLASTIC CONTAINER
GLYCINE, ACS
Glicina
Glicina [INN-Spanish]
Glicoamin
Gly
Glycin
Glycine
Glycine (JP15/USP)
Glycine [INN]
Glycine iron sulphate (1:1)
Glycine, homopolymer (VAN)
Glycine, labeled with carbon-14
Glycine, non-medical
Glycine-UL-14C hydrochloride
Glycinum
Glycinum [INN-Latin]
Glycocoll
Glycolixir
Glycosthene
Glykokoll
Glyzin
Gyn-Hydralin
Gyn-hydralin
H-Gly-OH
H2N-CH2-COOH
HSDB 495
Hampshire glycine
Hgly
InChI=1/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5
KST-1A2919
KST-1A8102
L-Glycine
L-alpha-amino acids
L001246
LS-218
Leimzucker
MolPort-000-871-607
NCGC00024503-01
NCGC00024503-02
NChemBio.2007.13-comp1
NSC 25936
NSC25936
P8791_SIGMA
Padil
Polyglycine II
S04-0135
Sucre de gelatine
Tocris-0219
UNII-TE7660XO1C
W328707_ALDRICH
WLN: Z1VQ
aminoacetic acid
an alpha amino acid ester
bmse000089
gly
glycine
nchem.554-comp2
nchembio.121-comp9
nchembio.145-comp33
nchembio.198-comp12
nchembio.265-comp9
nchembio.266-comp30
polyglycine
30Antibiotics, Antitubercular6972
31Antitubercular Agents1272
32Cephalosporins164
33Chelating Agents1365
34Calcium, Dietary5525
35Neurotransmitter Agents17734
36Anticoagulants2516
37Antiviral Agents9732
38Anti-Retroviral Agents3232
39Anti-HIV Agents3100
40
Citric Acidnutraceutical, vet_approved110677-92-9311
Synonyms:
2-Hydroxy-1,2,3-propanetricarboxylate
2-Hydroxy-1,2,3-propanetricarboxylic acid
2-Hydroxytricarballylic acid
3-Carboxy-3-hydroxypentane-1,5-dioate
3-Carboxy-3-hydroxypentane-1,5-dioic acid
Aciletten
Anhydrous citrate
Anhydrous citric acid
Chemfill
Citraclean
 
Citrate
Citretten
Citric acid
Citro
Citronensäure
E 330
Hydrocerol A
Kyselina citronova
Suby G
Uro-trainer
beta-Hydroxytricarballylate
beta-Hydroxytricarballylic acid
41CitrateNutraceutical1106

Interventional clinical trials:

idNameStatusNCT IDPhase
1The Treatment of Lenalidomide in Patients With POEMS SyndromeUnknown statusNCT00971685Phase 2
2Efficacy and Safety of Lenalidomide as a Treatment for Recurrent or Refractory POEMS Syndrome TrialCompletedNCT02193698Phase 2
3Pioglitazone Or Exercise to Treat Mild Cognitive Impairment (MCI)CompletedNCT00736996Phase 2
4POEMS Syndrome Treatment With LenalidomideRecruitingNCT01639898Phase 2
5Study to Evaluate Lenalidomide Plus Dexamethasone in Patients With Newly Diagnosed POEMS SyndromeActive, not recruitingNCT01816620Phase 2
6Bacteremia and Procalcitonin Levels in Peroral Endoscopic Myotomy for AchalasiaUnknown statusNCT01750385
7Ixazomib Citrate, Lenalidomide, and Dexamethasone in Treating Patients With POEMS SyndromeRecruitingNCT02921893
8Prospective Observational Epidemiologic Study of Maraviroc's SafetyActive, not recruitingNCT00665561

Search NIH Clinical Center for Poems Syndrome


Cochrane evidence based reviews: poems syndrome

Genetic Tests for Poems Syndrome

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Anatomical Context for Poems Syndrome

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MalaCards organs/tissues related to Poems Syndrome:

35
Skin, Endothelial, Bone, Bone marrow, Heart, Lymph node, Thyroid

Animal Models for Poems Syndrome or affiliated genes

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MGI Mouse Phenotypes related to Poems Syndrome:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.9FGF2, IL1B, IL6, TNF, VEGFA
2MP:00053908.8FGF2, IL1B, IL6, TNF, VEGFA
3MP:00107718.6ANGPT2, IL1B, IL6, TNF, VEGFA
4MP:00053858.1ANGPT2, FGF2, IL1B, IL6, TNF, VEGFA
5MP:00053917.7ANGPT2, FGF2, IL6, TNF, VEGFA

Publications for Poems Syndrome

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Articles related to Poems Syndrome:

(show top 50)    (show all 528)
idTitleAuthorsYear
1
OCULAR MANIFESTATIONS AND TREATMENT OUTCOMES IN CHINESE PATIENTS WITH POEMS SYNDROME. (27930460)
2016
2
Long-term outcome of patients with POEMS syndrome: An update of the Mayo Clinic experience. (26972803)
2016
3
An Occult Malignancy Behind a Demyelinating Disease: POEMS Syndrome. (27790622)
2016
4
POEMS Syndrome: A Rare Disease With A Challenging Diagnosis. (26742203)
2015
5
POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes) treated with autologous hematopoietic stem cell transplantation: a case report and literature review. (25726020)
2015
6
Cutaneous Manifestations in POEMS Syndrome: Case Report and Review. (26034475)
2015
7
Pentraxin-3 and VEGF in POEMS syndrome: a 2-year longitudinal study. (25447599)
2014
8
Correlation between serum level of vascular endothelial growth factor and subfoveal choroidal thickness in patients with POEMS syndrome. (25367833)
2014
9
Pulmonary hypertension in POEMS syndrome: resolution following radiotherapy. (25610609)
2014
10
Outcomes of patients with POEMS syndrome treated initially with radiation. (23699599)
2013
11
POEMS syndrome and Castleman disease. (24006526)
2013
12
Bevacizumab treatment followed by maintenance in life-threatening POEMS syndrome. (23334107)
2013
13
Comparison of imaging methods in POEMS syndrome. (22580861)
2012
14
Successful treatment with bortezomib and thalidomide for POEMS syndrome associated with multicentric mixed-type Castleman's disease. (21890654)
2011
15
The clinical study of POEMS syndrome in China. (20424579)
2010
16
POEMS syndrome - a unique presentation of a rare paraneoplastic syndrome. (22798312)
2010
17
Coexistence of primary AL amyloidosis and POEMS syndrome: efficacy of melphalan-dexamethasone and role of biochemical markers in monitoring the diseases course. (20029992)
2010
18
POEMS syndrome with an isolated lytic lesion and glomeruloid hemangiomas: report of one case]. (19701559)
2009
19
Lenalidomide therapy in a rare case of POEMS syndrome with kappa restriction. (19738540)
2009
20
Spontaneous recovery of adrenal insufficiency in POEMS syndrome. (19295942)
2009
21
Discrepancy between disease activity and levels of vascular endothelial growth factor in a patient with POEMS syndrome successfully treated with autologous stem-cell transplantation. (18660839)
2008
22
New strategy of treatment for POEMS syndrome--autologous peripheral blood stem cell transplantation and thalidomide therapy]. (18567358)
2008
23
POEMS syndrome with lambda chain deposition in hemangioma. (18573727)
2008
24
VEGF and osteosclerosis in POEMS syndrome. (18172647)
2008
25
IgM-lambda paraproteinemia with associated cutaneous lymphoplasmacytic infiltrate in a patient who meets diagnostic criteria for POEMS syndrome. (18342713)
2008
26
Efficacy of autologous peripheral blood stem cell transplantation in POEMS syndrome with polyneuropathy. (17268130)
2007
27
Polyneuropathy, organomegaly, endocrinopathy, M protein, skin changes: not always a POEMS syndrome. (16709518)
2006
28
Polyneuropathy in POEMS syndrome: role of angiogenic factors in the pathogenesis. (15975949)
2005
29
Thalidomide in POEMS syndrome: case report. (15114600)
2004
30
Crow-Fukase (POEMS) syndrome: a study of peripheral nerve biopsy in five new cases. (12904234)
2003
31
Long-term follow-up on a patient with incomplete POEMS syndrome undergoing high-dose therapy and autologous blood stem cell transplantation. (12360984)
2002
32
Reversible pulmonary hypertension in POEMS syndrome--another etiology of triggered pulmonary vasculopathy? (10978936)
2000
33
Abnormal FSH hypersecretion as an endocrinological manifestation of POEMS syndrome. (9625458)
1998
34
Long term melphalan-prednisolone chemotherapy for POEMS syndrome. (9328260)
1997
35
Pro-inflammatory cytokines: a pathogenic key of POEMS syndrome]. (8881441)
1996
36
Greatly raised vascular endothelial growth factor (VEGF) in POEMS syndrome. (8596427)
1996
37
Amyotrophic lateral sclerosis associated with multiple myeloma, endocrinopathy and skin changes suggestive of a POEMS syndrome variant. (7595623)
1995
38
Cryoglobulinemia and other dysproteinemias, familial Mediterranean fever, and POEMS syndrome. (7718425)
1995
39
POEMS syndrome: clinical, pathological and immunological study of a case. (7708142)
1994
40
Alopecia as a rare cutaneous manifestation of POEMS syndrome. (7918001)
1994
41
Angioendotheliomatosis associated with Castleman's lymphoma and POEMS syndrome. (8403477)
1993
42
POEMS syndrome, osteosclerotic myeloma and Castleman's disease: a case report. (1953537)
1991
43
Renal involvement in POEMS syndrome. (1944731)
1991
44
POEMS syndrome: an Italian case with diagnostic and therapeutic implications. (1804287)
1991
45
The kidney disease of Crow-Fukase (POEMS) syndrome: a clinico-pathological study of four cases. (1934663)
1991
46
Premature vascular calcification in a case of POEMS syndrome. (1756747)
1991
47
The endocrinopathy of POEMS syndrome. (2555917)
1989
48
Refractory ascites due to POEMS syndrome. (2535829)
1989
49
POEMS syndrome associated with cryoglobulinemia, lymphoma, multiple seborrheic keratosis, and ichthyosis. (2848065)
1988
50
POEMS syndrome presenting as systemic sclerosis. Clinical and pathologic study of a case with microangiopathic glomerular lesions. (3348253)
1988

Variations for Poems Syndrome

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Expression for genes affiliated with Poems Syndrome

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Search GEO for disease gene expression data for Poems Syndrome.

Pathways for genes affiliated with Poems Syndrome

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Pathways related to Poems Syndrome according to GeneCards Suite gene sharing:

(show all 45)
idSuper pathwaysScoreTop Affiliating Genes
19.6IL1B, IL6
29.6IL1B, IL6
3
Show member pathways
9.6FGF2, VEGFA
49.6FGF2, VEGFA
59.6FGF2, VEGFA
69.4IL6, TNF
79.4IL1B, TNF
89.4IL1B, TNF
9
Show member pathways
9.4IL1B, TNF
109.2FGF2, IL6, VEGFA
119.1IL6, TNF, VEGFA
12
Show member pathways
9.0IL1B, IL6, TNF
13
Show member pathways
9.0IL1B, IL6, TNF
149.0IL1B, IL6, TNF
15
Show member pathways
9.0IL1B, IL6, TNF
16
Show member pathways
9.0IL1B, IL6, TNF
179.0IL1B, IL6, TNF
18
Show member pathways
9.0IL1B, IL6, TNF
19
Show member pathways
9.0IL1B, IL6, TNF
209.0IL1B, IL6, TNF
219.0IL1B, IL6, TNF
229.0IL1B, IL6, TNF
239.0IL1B, IL6, TNF
249.0IL1B, IL6, TNF
259.0IL1B, IL6, TNF
269.0IL1B, IL6, TNF
279.0IL1B, IL6, TNF
289.0IL1B, IL6, TNF
299.0IL1B, IL6, TNF
309.0IL1B, IL6, TNF
319.0FGF2, TNF, VEGFA
329.0FGF2, TNF, VEGFA
338.9ANGPT2, IL6, VEGFA
348.6IL1B, IL6, TNF, VEGFA
358.6IL1B, IL6, TNF, VEGFA
368.6IL1B, IL6, TNF, VEGFA
37
Show member pathways
8.5FGF2, IL1B, IL6, TNF
388.3ANGPT2, FGF2, IL6, VEGFA
39
Show member pathways
8.3ANGPT2, FGF2, IL1B, IL6
408.2ANGPT2, IL1B, IL6, TNF
41
Show member pathways
7.6ANGPT2, FGF2, IL1B, IL6, TNF
42
Show member pathways
7.6ANGPT2, FGF2, IL1B, IL6, TNF
43
Show member pathways
7.6ANGPT2, FGF2, IL1B, IL6, TNF
44
Show member pathways
7.3ANGPT2, FGF2, IL1B, IL6, TNF, VEGFA
45
Show member pathways
7.3ANGPT2, FGF2, IL1B, IL6, TNF, VEGFA

GO Terms for genes affiliated with Poems Syndrome

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Cellular components related to Poems Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056157.3ANGPT2, FGF2, IL1B, IL6, TNF, VEGFA
2extracellular regionGO:00055767.0ANGPT2, FGF2, IL1B, IL6, TNF, VEGFA

Biological processes related to Poems Syndrome according to GeneCards Suite gene sharing:

(show all 50)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of vascular endothelial growth factor receptor signaling pathwayGO:003094910.3IL1B, VEGFA
2cell migration involved in sprouting angiogenesisGO:000204210.3FGF2, VEGFA
3positive regulation of blood vessel endothelial cell migrationGO:004353610.3FGF2, VEGFA
4positive regulation of chemokine productionGO:003272210.1IL6, TNF
5epithelial cell proliferation involved in salivary gland morphogenesisGO:006066410.1IL6, TNF
6positive regulation of protein complex assemblyGO:003133410.1TNF, VEGFA
7positive chemotaxisGO:005091810.1FGF2, VEGFA
8positive regulation of calcidiol 1-monooxygenase activityGO:006055910.1IL1B, TNF
9positive regulation of membrane protein ectodomain proteolysisGO:005104410.1IL1B, TNF
10sequestering of triglycerideGO:003073010.1IL1B, TNF
11chronic inflammatory response to antigenic stimulusGO:000243910.1IL1B, TNF
12regulation of establishment of endothelial barrierGO:190314010.1IL1B, TNF
13positive regulation of chemokine biosynthetic processGO:004508010.1IL1B, TNF
14regulation of angiogenesisGO:004576510.0FGF2, IL6
15positive regulation of NF-kappaB import into nucleusGO:004234610.0IL1B, TNF
16protein kinase B signalingGO:004349110.0IL1B, TNF
17lipopolysaccharide-mediated signaling pathwayGO:003166310.0IL1B, TNF
18positive regulation of heterotypic cell-cell adhesionGO:003411610.0IL1B, TNF
19negative regulation of lipid storageGO:001088810.0IL6, TNF
20positive regulation of fever generationGO:003162210.0IL1B, TNF
21negative regulation of lipid catabolic processGO:005099510.0IL1B, TNF
22negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:20012409.9IL1B, TNF
23regulation of I-kappaB kinase/NF-kappaB signalingGO:00431229.9IL1B, TNF
24positive regulation of JUN kinase activityGO:00435079.9IL1B, TNF
25positive regulation of interleukin-8 productionGO:00327579.8IL1B, TNF
26positive regulation of phagocytosisGO:00507669.7IL1B, TNF
27positive regulation of cell divisionGO:00517819.7FGF2, IL1B, VEGFA
28positive regulation of epithelial cell proliferationGO:00506799.6FGF2, IL6, VEGFA
29negative regulation of blood vessel endothelial cell migrationGO:00435379.5ANGPT2, FGF2
30positive regulation of NF-kappaB transcription factor activityGO:00510929.5IL1B, IL6, TNF
31positive regulation of smooth muscle cell proliferationGO:00486619.5FGF2, IL6, TNF
32positive regulation of sequence-specific DNA binding transcription factor activityGO:00510919.5IL1B, IL6, TNF
33positive regulation of protein kinase B signalingGO:00518979.5FGF2, IL6, TNF
34positive regulation of interleukin-6 productionGO:00327559.5IL1B, IL6, TNF
35positive regulation of MAP kinase activityGO:00434069.4FGF2, TNF, VEGFA
36positive regulation of nitric oxide biosynthetic processGO:00454299.3IL1B, IL6, TNF
37positive regulation of peptidyl-serine phosphorylationGO:00331389.3IL6, TNF, VEGFA
38wound healingGO:00420609.3FGF2, IL1B, IL6
39agingGO:00075689.3FGF2, IL1B, IL6
40MAPK cascadeGO:00001659.2FGF2, IL1B, TNF
41activation of MAPK activityGO:00001879.1FGF2, IL1B, TNF
42angiogenesisGO:00015259.1ANGPT2, FGF2, VEGFA
43positive regulation of protein phosphorylationGO:00019349.0FGF2, IL1B, TNF, VEGFA
44leukocyte migrationGO:00509008.9ANGPT2, IL1B, TNF
45positive regulation of transcription, DNA-templatedGO:00458938.8FGF2, IL1B, IL6, TNF
46positive regulation of angiogenesisGO:00457668.7ANGPT2, FGF2, IL1B, VEGFA
47response to hypoxiaGO:00016668.7ANGPT2, IL1B, VEGFA
48positive regulation of ERK1 and ERK2 cascadeGO:00703748.2FGF2, IL1B, IL6, TNF
49positive regulation of gene expressionGO:00106288.2FGF2, IL1B, IL6, TNF, VEGFA
50positive regulation of transcription from RNA polymerase II promoterGO:00459448.1FGF2, IL1B, IL6, TNF, VEGFA

Molecular functions related to Poems Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1chemoattractant activityGO:00420569.7FGF2, VEGFA
2growth factor activityGO:00080839.2FGF2, IL6, VEGFA
3cytokine activityGO:00051257.8FGF2, IL1B, IL6, TNF, VEGFA

Sources for Poems Syndrome

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet