Poland Syndrome malady
Rare diseases, Reproductive diseases, Bone diseases, Fetal diseases, Oral diseases categories
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21Genetics Home Reference, 42NIH Rare Diseases, 65Wikipedia, 46OMIM, 32MalaCards
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Genetics Home Reference:21 Poland syndrome is a disorder in which affected individuals are born with missing or abnormal muscles on one side of the chest wall. Most individuals with Poland syndrome also have abnormalities of the hand, which often involve shortened fingers, partial fusion of the fingers, or both. The hand abnormalities usually affect the same (ipsilateral) side of the body as those of the chest. Poland syndrome affects the right side of the body more often than the left side.
MalaCards based summary: Poland Syndrome, also known as poland anomaly, is related to dextrocardia and adams oliver syndrome, and has symptoms including asymmetric rib cage/thorax, breast tissue/mammary gland absence/aplasia and hypoplastic/absent nipples. Affiliated tissues include breast, bone and liver.
NIH Rare Diseases:42 Poland syndrome is characterized byÂ an underdevelopedÂ or absentÂ chest muscleÂ on one side of the body, absence of the breastbone portion (sternal) of theÂ chest muscle,Â and webbing of the fingersÂ of the hand on the same side. the cause of poland syndrome is not known. this syndrome is nearly always sporadic. it tends to be right sided and isÂ more common inÂ boys than girls. last updated: 6/25/2011
Wikipedia:65 Poland syndrome (also Poland\'s syndrome, Poland\'s syndactyly, Poland sequence, and Poland\'s anomaly)... more...
Description from OMIM:46 173800
Poland Syndrome, Aliases & Descriptions:
Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Fetal diseases
Anatomical: Reproductive diseases, Bone diseases, Oral diseases
Rare gynaecological and obstetric diseases
Rare bone diseases
Developmental anomalies during embryogenesis
Characteristics (Orphanet epidemiological data):48
Inheritance: Autosomal dominant,Sporadic; Prevalence: 1-9/100000; Age of onset: Neonatal/infancy; Age of death: Normal
Symptoms by clinical synopsis from OMIM:173800
Clinical features from OMIM:173800
Symptoms:48 (show all 33)
HPO human phenotypes related to Poland Syndrome:(show all 45)
MalaCards organs/tissues related to Poland Syndrome:32
Breast, Bone, Liver, Heart, Kidney, Skin, Spleen, Retina
Articles related to Poland Syndrome:(show top 50) (show all 116)
Search GEO for disease gene expression data for Poland Syndrome.
26ICD10 via Orphanet
35MESH via Orphanet
47OMIM via Orphanet
58SNOMED-CT via Orphanet
63UMLS via Orphanet