MCID: PLN006
MIFTS: 54

Poland Syndrome malady

Categories: Rare diseases, Reproductive diseases, Bone diseases, Fetal diseases, Oral diseases

Aliases & Classifications for Poland Syndrome

Aliases & Descriptions for Poland Syndrome:

Name: Poland Syndrome 54 12 50 25 56 42 14 69
Poland Sequence 12 50 25 56
Poland Anomaly 12 50 25 56
Poland Syndactyly 50 25
Poland's Syndrome 50 25
Unilateral Defect of Pectoralis Muscle and Syndactyly of the Hand 50
Unilateral Defect of Pectoralis Major and Syndactyly of the Hand 25
Poland's Syndactyly 12
Poland's Anomaly 25

Characteristics:

Orphanet epidemiological data:

56
poland syndrome
Inheritance: Autosomal dominant,Not applicable; Prevalence: 1-9/100000 (Europe); Age of onset: Infancy,Neonatal; Age of death: normal life expectancy;

HPO:

32
poland syndrome:
Inheritance autosomal dominant inheritance


Classifications:



External Ids:

OMIM 54 173800
Disease Ontology 12 DOID:12961
ICD10 33 Q79.8
MeSH 42 D011045
NCIt 47 C85017
SNOMED-CT 64 205524002 38371006
Orphanet 56 ORPHA2911
MESH via Orphanet 43 D011045
UMLS via Orphanet 70 C0032357
ICD10 via Orphanet 34 Q79.8
UMLS 69 C0032357

Summaries for Poland Syndrome

NIH Rare Diseases : 50 poland syndrome is characterized by an underdeveloped or absent chest muscle on one side of the body, absence of the breastbone portion (sternal) of the chest muscle, and webbing of the fingers of the hand on the same side. the cause of poland syndrome is not known. this syndrome is nearly always sporadic. it tends to occur on the right side and is more common in boys than girls. treatment typically involves surgical correction of the chest wall deformities. last updated: 10/5/2016

MalaCards based summary : Poland Syndrome, also known as poland sequence, is related to oliver syndrome and webster deming syndrome, and has symptoms including short neck, finger syndactyly and scoliosis. An important gene associated with Poland Syndrome is REV3L (REV3 Like, DNA Directed Polymerase Zeta Catalytic Subunit), and among its related pathways/superpathways are Acyl chain remodelling of PE and Defective CSF2RA causes pulmonary surfactant metabolism dysfunction 4 (SMDP4). The drugs Beractant and Poractant alfa have been mentioned in the context of this disorder. Affiliated tissues include breast, bone and liver, and related phenotypes are cellular and craniofacial

Genetics Home Reference : 25 Poland syndrome is a disorder in which affected individuals are born with missing or underdeveloped muscles on one side of the body, resulting in abnormalities that can affect the chest, shoulder, arm, and hand. The extent and severity of the abnormalities vary among affected individuals.

OMIM : 54 Poland syndrome consists of unilateral absence or hypoplasia of the pectoralis muscle, most frequently involving the... (173800) more...

Wikipedia : 71 Poland syndrome, named after British surgeon Alfred Poland, is a rare birth defect characterized by... more...

Related Diseases for Poland Syndrome

Diseases related to Poland Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 43)
id Related Disease Score Top Affiliating Genes
1 oliver syndrome 26.1 ALX3 CHN1 HK1 HOXA2 HRASLS2 HRASLS5
2 webster deming syndrome 11.1
3 breasts and/or nipples, aplasia or hypoplasia of, 2 10.8
4 idiopathic interstitial pneumonia 10.2 SFTPA1 SFTPA2
5 cranial nerve malignant neoplasm 10.2 SFTPA1 SFTPA2
6 glomangiomatosis 10.1 ALX3 HOXA2
7 infant gynecomastia 10.1 NF1 PAX6
8 scn9a-related inherited erythromelalgia 10.1 SFTPA1 SFTPA2
9 interstitial keratitis 10.1 CHN1 PLA2G16
10 amyotrophic neuralgia 10.0 CHN1 PAX6 TUBB3
11 folic acid deficiency anemia 10.0 NF1 SFTPA1 SFTPA2
12 pontocerebellar hypoplasia 10.0 CHN1 PAX6 TUBB3
13 dextrocardia 10.0
14 alopecia areata 9.9 CHN1 NF1 TUBB3
15 tubulointerstitial nephritis with uveitis 9.9 CHN1 TUBB3
16 breast reconstruction 9.7
17 adams-oliver syndrome 9.6
18 muscular atrophy 9.6
19 breast cancer 9.6
20 klippel-feil syndrome 9.6
21 syndactyly 9.6
22 craniofrontonasal dysplasia 9.6
23 hydranencephaly 9.6
24 spinal muscular atrophy 9.4
25 ductal carcinoma in situ 9.4
26 aberrant subclavian artery 9.4
27 myelomeningocele 9.4
28 cavernous malformation 9.4
29 neuroblastoma 9.4
30 transsexualism 9.4
31 pericardial effusion 9.4
32 moebius syndrome 9.4
33 pernicious anemia 9.4
34 lipoma 9.4
35 mitral valve stenosis 9.4
36 hypogonadism 9.4
37 hyperinsulinism 9.4
38 pulmonary hypertension 9.4
39 thoracic outlet syndrome 9.4
40 hemangioma 9.4
41 hypogonadotropism 9.4
42 leukemia 9.4
43 situs inversus 9.4

Graphical network of the top 20 diseases related to Poland Syndrome:



Diseases related to Poland Syndrome

Symptoms & Phenotypes for Poland Syndrome

Symptoms by clinical synopsis from OMIM:

173800

Clinical features from OMIM:

173800

Human phenotypes related to Poland Syndrome:

56 32 (show all 44)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 short neck 56 32 Occasional (29-5%) HP:0000470
2 finger syndactyly 56 32 Frequent (79-30%) HP:0006101
3 scoliosis 56 32 Occasional (29-5%) HP:0002650
4 abnormality of the ulna 56 32 Occasional (29-5%) HP:0002997
5 microcephaly 56 32 Occasional (29-5%) HP:0000252
6 cone-shaped epiphysis 56 32 Occasional (29-5%) HP:0010579
7 reduced bone mineral density 56 32 Occasional (29-5%) HP:0004349
8 low posterior hairline 56 32 Occasional (29-5%) HP:0002162
9 aplasia/hypoplasia of the nipples 56 32 Very frequent (99-80%) HP:0006709
10 abnormal dermatoglyphics 56 32 Occasional (29-5%) HP:0007477
11 small hand 56 32 Frequent (79-30%) HP:0200055
12 renal hypoplasia/aplasia 56 32 Occasional (29-5%) HP:0008678
13 split hand 56 32 Frequent (79-30%) HP:0001171
14 acute leukemia 56 32 Occasional (29-5%) HP:0002488
15 hemivertebrae 56 32 Occasional (29-5%) HP:0002937
16 abnormality of the liver 56 32 Occasional (29-5%) HP:0001392
17 neoplasm of the breast 56 32 Occasional (29-5%) HP:0100013
18 dextrocardia 56 32 Occasional (29-5%) HP:0001651
19 congenital diaphragmatic hernia 56 32 Occasional (29-5%) HP:0000776
20 aplasia/hypoplasia of the thumb 56 32 Occasional (29-5%) HP:0009601
21 abnormality of the lower limb 56 32 Occasional (29-5%) HP:0002814
22 absent hand 56 32 Occasional (29-5%) HP:0004050
23 asymmetry of the thorax 56 32 Very frequent (99-80%) HP:0001555
24 retinal hamartoma 56 32 Occasional (29-5%) HP:0009594
25 abnormality of the humerus 56 32 Occasional (29-5%) HP:0003063
26 aplasia/hypoplasia of the breasts 56 32 Very frequent (99-80%) HP:0010311
27 short ribs 56 32 Occasional (29-5%) HP:0000773
28 unilateral brachydactyly 56 32 Frequent (79-30%) HP:0006008
29 aplasia/hypoplasia of the sternum 56 32 Occasional (29-5%) HP:0006714
30 lack of subcutaneous fatty tissue 56 32 Very frequent (99-80%) HP:0007519
31 sprengel anomaly 32 HP:0000912
32 abnormality of the ribs 56 Occasional (29-5%)
33 abnormality of the hand 56 Frequent (79-30%)
34 rib fusion 32 HP:0000902
35 abnormality of the sternum 56 Occasional (29-5%)
36 syndactyly 32 HP:0001159
37 abnormality of the breast 32 HP:0000769
38 hypoplasia of deltoid muscle 32 HP:0030241
39 absence of pectoralis minor muscle 32 HP:0005255
40 unilateral absence of pectoralis major muscle 32 HP:0005256
41 unilateral oligodactyly 32 HP:0006230
42 hypoplasia of serratus anterior muscle 32 HP:0009011
43 hypoplasia of latissimus dorsi muscle 32 HP:0009026
44 unilateral hypoplasia of pectoralis major muscle 32 HP:0011959

MGI Mouse Phenotypes related to Poland Syndrome:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10 PAX6 PLA2G16 PRTN3 REV3L TUBB3 ALX3
2 craniofacial MP:0005382 9.7 ALX3 HOXA2 LRP4 NF1 NOTCH1 PAX6
3 embryo MP:0005380 9.56 ALX3 HOXA2 LRP4 NF1 NOTCH1 PAX6
4 respiratory system MP:0005388 9.23 ALX3 HOXA2 LRP4 NF1 NOTCH1 PAX6

Drugs & Therapeutics for Poland Syndrome

Drugs for Poland Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 441)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Beractant Approved Phase 4 108778-82-1
2 Poractant alfa Approved Phase 4 129069-19-8
3
Cyproterone Acetate Approved, Investigational Phase 4 427-51-0
4
Ethinyl Estradiol Approved Phase 4,Phase 3 57-63-6 5991
5
Metformin Approved Phase 4,Phase 3,Phase 2 657-24-9 14219 4091
6
Simvastatin Approved Phase 4,Phase 3 79902-63-9 54454
7
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-78-2 2244
8
Eptifibatide Approved, Investigational Phase 4,Phase 3,Phase 2 188627-80-7 123610
9
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2 9005-49-6 772 46507594
10
Alverine Approved Phase 4 150-59-4 3678
11 Simethicone Approved Phase 4
12
Ritonavir Approved, Investigational Phase 4,Phase 3,Phase 2 155213-67-5 392622
13
Denileukin diftitox Approved, Investigational Phase 4 173146-27-5
14
Insulin Glargine Approved Phase 4 160337-95-1
15
Insulin Lispro Approved Phase 4 133107-64-9
16
Zinc Approved Phase 4,Phase 3 7440-66-6 32051 23994
17
Everolimus Approved Phase 4,Phase 3 159351-69-6 6442177
18
Paclitaxel Approved, Vet_approved Phase 4 33069-62-4 36314
19
Sirolimus Approved, Investigational Phase 4,Phase 3 53123-88-9 5284616 6436030 46835353
20
Interferon beta-1b Approved Phase 4,Phase 3 145155-23-3
21
Pancrelipase Approved Phase 4,Phase 3 53608-75-6
22
Abacavir Approved, Investigational Phase 4,Phase 3 136470-78-5 65140 441300
23
Tenofovir Approved, Investigational Phase 4,Phase 3,Phase 2 147127-20-6 464205
24
Apixaban Approved Phase 4,Phase 3,Phase 2 503612-47-3 10182969
25
Somatostatin Approved Phase 4,Phase 3,Phase 2 38916-34-6, 51110-01-1 53481605
26
Ticlopidine Approved Phase 4,Phase 3,Phase 2 55142-85-3 5472
27
Darunavir Approved Phase 4,Phase 3 635728-49-3, 206361-99-1 213039
28
Maraviroc Approved, Investigational Phase 4,Phase 2,Phase 3 376348-65-1 3002977
29
Amiodarone Approved, Investigational Phase 4 1951-25-3 2157
30
Propafenone Approved Phase 4 54063-53-5 4932
31
Clopidogrel Approved, Nutraceutical Phase 4,Phase 3,Phase 2 120202-66-6, 113665-84-2 60606
32
Menadione Approved, Nutraceutical Phase 4,Phase 3 58-27-5 4055
33
Phytonadione Approved, Nutraceutical Phase 4,Phase 3 84-80-0 4812 5284607
34
Resveratrol Experimental, Investigational Phase 4 501-36-0, 955365-80-7 24856436 445154
35 Pulmonary Surfactants Phase 4
36 Respiratory System Agents Phase 4
37 Androgen Antagonists Phase 4
38 Androgens Phase 4
39 Contraceptive Agents Phase 4,Phase 3
40 Contraceptive Agents, Male Phase 4
41 Contraceptives, Oral Phase 4,Phase 3
42
Cyproterone Phase 4 2098-66-0 5284537
43 Hormone Antagonists Phase 4,Phase 3,Phase 2
44 Hormones Phase 4,Phase 3,Phase 2
45 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2
46 Hypoglycemic Agents Phase 4,Phase 3,Phase 2
47 Liver Extracts Phase 4,Phase 3
48 pancreatic polypeptide Phase 4
49 Anticholesteremic Agents Phase 4,Phase 3
50 Antimetabolites Phase 4,Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 319)
id Name Status NCT ID Phase
1 Brain Oxygenation and Function of Preterm Newborns During Administration of Two Different Surfactant Preparations Unknown status NCT01941524 Phase 4
2 PCOS, Therapy and Markers of Cardiovascular Risk Unknown status NCT01798875 Phase 4
3 Omega-3 Fatty Acids Efficacy in First-episode of Schizophrenia Unknown status NCT02210962 Phase 4
4 Disease-Specific Questionnaire in Assessing Quality of Life in Patients With Gastrointestinal-Related Neuroendocrine Tumors Unknown status NCT00454376 Phase 4
5 Endothelial Progenitor Cells-capture Stents in Acute Coronary Syndromes Completed NCT00494247 Phase 4
6 INFLACOR - Clinical and Genetic Predictors of Inflammation Related Complications After Heart Surgery Completed NCT01020409 Phase 4
7 Safety and Clinical Outcomes in Hunter Syndrome Patients 5 Years of Age and Younger Receiving Idursulfase Therapy Completed NCT00607386 Phase 4
8 Salusin-alpha - a New Factor in the Pathogenesis of Lipid Abnormalities in Hemodialysis Patients Completed NCT01448174 Phase 4
9 Clinical Effects of Eptifibatide Administration in High Risk Patients Presenting With Non-ST Segment Elevation Acute Coronary Syndrome (NSTE-ACS) Requiring Urgent Coronary Artery Bypass Graft Surgery in Short- and Long-Term Follow-up Completed NCT01863134 Phase 4
10 Randomized Clinical Trial of Posterior Retroperitoneoscopic Adrenalectomy Versus Lateral Laparoscopic Adrenalectomy Completed NCT01959711 Phase 4
11 Efficacy and Safety of Meteospasmyl® in Irritable Bowel Syndrome Completed NCT00542295 Phase 4
12 Fondaparinux Trial With Unfractionated Heparin (UFH) During Revascularization in Acute Coronary Syndromes (ACS) Completed NCT00790907 Phase 4
13 Study of Reyataz in HIV-infected Patients With Lipodystrophy Syndrome Completed NCT00135356 Phase 4
14 Glucomannan for the Treatment of Abdominal Pain-related Functional Gastrointestinal Disorders in Childhood Completed NCT01495806 Phase 4
15 Study of ONTAK (Denileukin Diftitox) in Previously Treated Cutaneous T-Cell Lymphoma Patients Completed NCT00051012 Phase 4
16 Study of ONTAK (Denileukin Diftitox) in Cutaneous T-Cell Lymphoma (CTCL) Patients Completed NCT00050999 Phase 4
17 Hyperglycemia and Cardiovascular Outcomes With Type 2 Diabetes Completed NCT00191282 Phase 4
18 The Dual Antiplatelet Therapy Study (DAPT Study) Completed NCT00977938 Phase 4
19 Safety and Efficacy of Cerezyme® Infusions Every 4 Weeks Versus Every 2 Weeks in Type 1 Gaucher Disease Completed NCT00364858 Phase 4
20 Adult Bipolar Mania Completed NCT00931723 Phase 4
21 Follow-up Study After 11 Years of Patients Who Were Included in the BENEFIT Trial (304747) With a First Demyelinating Event Suggestive of Multiple Sclerosis Completed NCT01795872 Phase 4
22 Control of Steatorrhea in Participants With Cystic Fibrosis and Exocrine Pancreatic Insufficiency Completed NCT01327703 Phase 4
23 Clinical Utility Of Genetic Screening For HLA-B*5701, On Susceptibility To Abacavir Hypersensitivity Completed NCT00340080 Phase 4
24 A Phase 4 Cross-Sectional Study of Bone Mineral Density in HIV-1 Infected Subjects Completed NCT01850212 Phase 4
25 The Use of DPP-4 Inhibitors in Short Bowel Syndrome Recruiting NCT02653131 Phase 4
26 Effects of Simvastatin and Micronized Trans-resveratrol Treatment on Polycystic Ovary Syndrome (PCOS) Patients Recruiting NCT02766803 Phase 4
27 A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart Recruiting NCT02415400 Phase 4
28 Study to Allow Access to Pasireotide for Patients Benefiting From Pasireotide Treatment in a Novartis-sponsored Study. Recruiting NCT01794793 Phase 4
29 A Rollover Study to Provide Continued Treatment With Eltrombopag Recruiting NCT01957176 Phase 4
30 Testing Responsiveness to Platelet Inhibition on Chronic Antiplatelet Treatment For Acute Coronary Syndromes Trial Active, not recruiting NCT01959451 Phase 4
31 Early Treatment of Atrial Fibrillation for Stroke Prevention Trial Active, not recruiting NCT01288352 Phase 4
32 Strategic Timing of Antiretroviral Treatment Active, not recruiting NCT00867048 Phase 4
33 Maraviroc Versus Etravirine In Combination With Antiretroviral Therapy In Drug Experienced HIV And Hepatitis Co-Infected Patients Withdrawn NCT00782301 Phase 4
34 A Study of GSK1349572 Versus Raltegravir (RAL) With Investigator Selected Background Regimen in Antiretroviral-Experienced, Integrase Inhibitor-Naive Adults Unknown status NCT01231516 Phase 3
35 Chemotherapy Plus Surgery in Treating Children at Risk of or With Stage I Wilms' Tumor Unknown status NCT00003804 Phase 3
36 Evaluation of Cardiovascular Outcomes in Patients With Type 2 Diabetes After Acute Coronary Syndrome During Treatment With AVE0010 (Lixisenatide) Completed NCT01147250 Phase 3
37 Influenza Vaccination in Prevention From Acute Coronary Events in Coronary Artery Disease - FLUCAD Study Completed NCT00371098 Phase 2, Phase 3
38 A Comparison of Ticagrelor (AZD6140) and Clopidogrel in Patients With Acute Coronary Syndrome Completed NCT00391872 Phase 3
39 12-Week Efficacy and Safety Study of Ibodutant in Women With Irritable Bowel Syndrome With Diarrhea (IBS-D) Completed NCT02107196 Phase 3
40 Study of Teduglutide Effectiveness in Parenteral Nutrition (PN)-Dependent Short Bowel Syndrome (SBS) Subjects Completed NCT00798967 Phase 3
41 A Survival Study in Patients With High Risk Myelodysplastic Syndromes Comparing Azacitidine Versus Conventional Care Completed NCT00071799 Phase 3
42 A Comparison of Prasugrel and Clopidogrel in Acute Coronary Syndrome Subjects Completed NCT00699998 Phase 3
43 A Phase 3 Clinical Outcomes Study to Compare the Incidence of Major Adverse Cardiovascular Events in Subjects Presenting With Acute Coronary Syndrome Treated With Losmapimod Compared to Placebo (LATITUDE-TIMI 60) Completed NCT02145468 Phase 3
44 Study of Rufinamide in Pediatric Subjects 1 to Less Than 4 Years of Age With Lennox-Gastaut Syndrome Inadequately Controlled With Other Anti-epileptic Drugs Completed NCT01405053 Phase 3
45 Cardiovascular Outcomes Study of Alogliptin in Patients With Type 2 Diabetes and Acute Coronary Syndrome Completed NCT00968708 Phase 3
46 Open-Label Study of Teduglutide for Subjects With PN-Dependent Short Bowel Syndrome (SBS) Completed NCT00930644 Phase 3
47 A Study of RO4607381 in Stable Coronary Heart Disease Patients With Recent Acute Coronary Syndrome Completed NCT00658515 Phase 3
48 Study Evaluating Combination of Levonorgestrel and Ethinyl Estradiol in Pre-Menstrual Dysphoric Disorder Completed NCT00195559 Phase 3
49 Safety and Efficacy Study of Teduglutide in Subjects With Short Bowel Syndrome Completed NCT00081458 Phase 3
50 An Efficacy and Safety Study for Rivaroxaban in Patients With Acute Coronary Syndrome Completed NCT00809965 Phase 3

Search NIH Clinical Center for Poland Syndrome

Cochrane evidence based reviews: poland syndrome

Genetic Tests for Poland Syndrome

Anatomical Context for Poland Syndrome

MalaCards organs/tissues related to Poland Syndrome:

39
Breast, Bone, Liver, Spleen, Retina

Publications for Poland Syndrome

Articles related to Poland Syndrome:

(show top 50) (show all 131)
id Title Authors Year
1
Congenital hyperinsulinism and Poland syndrome in association with 10p13-14 duplication. ( 28458900 )
2017
2
Free gracilis flap for chest wall reconstruction in male patient with Poland syndrome after implant failure. ( 27833290 )
2016
3
Body Image Disorders and Surgical Timing in Patients Affected by Poland Syndrome: Data Analysis of 58 Case Studies. ( 27018681 )
2016
4
Assessment of copy number variations in 120 patients with Poland syndrome. ( 27884122 )
2016
5
Proposal of the TBN Classification of Thoracic Anomalies and Treatment Algorithm for Poland Syndrome. ( 27348639 )
2016
6
Bipolar Latissimus Dorsi Transfer through a Single Incision: First Key-Step in Poland Syndrome Chest Deformity. ( 27622115 )
2016
7
Isolated left pectoralis major muscle hypoplasia in Poland syndrome. ( 26823450 )
2016
8
Unilateral hypertransparency on chest radiograph: the congenital Poland Syndrome. ( 28009035 )
2016
9
Previous Information About Poland Syndrome Should Be Reviewed. ( 26522562 )
2015
10
Clinical analysis of 113 patients with Poland syndrome. ( 25633462 )
2015
11
Integrated algorithm for reconstruction of complex forms of Poland syndrome: 20-year outcomes. ( 26159469 )
2015
12
Mobius syndrome and poland syndrome presenting together in a single patient. ( 25834693 )
2015
13
eComment. Could this be a first depiction of Poland syndrome? ( 25791966 )
2015
14
SPINAL MUSCULAR ATROPHY TYPE 1 AND POLAND SYNDROME: A NOVEL ASSOCIATION IN A MEXICAN FEMALE INFANT. ( 26625666 )
2015
15
Bipolar Latissimus Dorsi Transfer for Restoration of Pectoralis Major Function in Poland Syndrome. ( 25046677 )
2014
16
Poland syndrome. ( 24959021 )
2014
17
Articulated endoscopic linear cutter stapler facilitates minimal access harvest of the latissimus dorsi muscle flap for chest wall reconstruction in poland syndrome. ( 25347672 )
2014
18
Clinical application of Nuss procedure for chest wall deformity in Poland syndrome. ( 26336460 )
2014
19
Poland syndrome coexisting with blaschkolinear congenital melanocytic nevi. ( 25007065 )
2014
20
De novo deletion of chromosome 11q12.3 in monozygotic twins affected by Poland Syndrome. ( 24885342 )
2014
21
Hybrid procedure for Poland syndrome associated with a Gerbode-type defect. ( 24854181 )
2014
22
Poland syndrome: an algorithm to select the appropriate chest wall surgical reconstructive treatment. ( 25074240 )
2014
23
Customized Titanium Implant for Chest Wall Reconstruction in Complex Poland Syndrome. ( 25243105 )
2014
24
Poland syndrome involving the left hemithorax with dextrocardia and herniation of the spleen. ( 24567179 )
2014
25
Autologous Reconstruction of a Complex Form of Poland Syndrome Using 2 Abdominal Perforator Free Flaps. ( 24322640 )
2013
26
Laparoscopically harvested omental flap for breast reconstruction in Poland syndrome. ( 23972535 )
2013
27
A hyperlucent hemithorax on a chest radiograph: Poland syndrome as an uncommon extrapulmonic source. ( 23841253 )
2013
28
A case of spontaneous chylous pericardial effusion in Poland syndrome. ( 23918317 )
2013
29
Optic Disc Dysplasia in Poland Syndrome. ( 23647425 )
2013
30
A rare association of pulmonary hypertension and dextrocardia with Poland syndrome. ( 24054492 )
2013
31
Poland syndrome: from embryological basis to plastic surgery. ( 23420344 )
2013
32
Chest wall reconstruction with methacrylate prosthesis in Poland syndrome. ( 23453291 )
2013
33
Poland syndrome a rare congenital anomaly. ( 24339551 )
2013
34
A unique case of right-sided Poland syndrome with true dextrocardia and total situs inversus. ( 23011746 )
2013
35
Hand and upper limb anomalies in Poland syndrome: a new proposal of classification. ( 22955538 )
2012
36
Rare combination of dextrocardia with right-sided Poland syndrome. ( 23006716 )
2012
37
Poland syndrome associated with pernicious anemia and gastric dysplasia. ( 24385744 )
2012
38
Poland syndrome and breast tumor: a case report and review of the literature. ( 22231415 )
2012
39
Poland syndrome with extracorporeal intercostal liver herniation and thoracic myelomeningocele. ( 22244430 )
2012
40
Poland syndrome with a rare association. ( 23547414 )
2012
41
Poland syndrome with Mullerian agenesis: a rare occurrence. ( 22226538 )
2012
42
Chest wall repair in Poland syndrome: complex single-stage surgery including Vertical Expandable Prosthetic Titanium Rib stabilization--a case report. ( 22424369 )
2012
43
Breast and chest wall reconstruction with the transverse musculocutaneous gracilis flap in Poland syndrome. ( 23018691 )
2012
44
Pleural damage during capsulectomy and exchange of long-standing breast implants in Poland syndrome: a cautionary tale. ( 21750456 )
2012
45
Poland syndrome. ( 23409420 )
2012
46
Multimodality imaging of Poland syndrome with dextrocardia and limb anomalies. ( 22785521 )
2012
47
A rare poland syndrome deformity: humero-pectoral band. ( 22654415 )
2011
48
Successful use of squeezed-fat grafts to correct a breast affected by Poland syndrome. ( 20953956 )
2011
49
Poland syndrome associated with ipsilateral lipoma and dextrocardia. ( 22115239 )
2011
50
Right-sided chest pain in Poland syndrome. ( 21959638 )
2011

Variations for Poland Syndrome

Copy number variations for Poland Syndrome from CNVD:

7
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1 35927 1 69500000 84700000 Deletion Poland''s syndrome
2 104857 16 73300000 78200000 Duplication Poland''s syndrome
3 263628 X 49700000 54700000 Duplication Poland''s syndrome

Expression for Poland Syndrome

Search GEO for disease gene expression data for Poland Syndrome.

Pathways for Poland Syndrome

GO Terms for Poland Syndrome

Cellular components related to Poland Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 clathrin-coated endocytic vesicle GO:0045334 8.96 SFTPA1 SFTPA2
2 lamellar body GO:0042599 8.62 SFTPA1 SFTPA2

Biological processes related to Poland Syndrome according to GeneCards Suite gene sharing:

(show all 12)
id Name GO ID Score Top Affiliating Genes
1 lipid catabolic process GO:0016042 9.63 HRASLS2 PLA2G16 RARRES3
2 motor neuron axon guidance GO:0008045 9.51 CHN1 HOXA2
3 negative regulation of ossification GO:0030279 9.49 LRP4 NOTCH1
4 positive regulation of neuroblast proliferation GO:0002052 9.48 NOTCH1 PAX6
5 negative regulation of neurogenesis GO:0050768 9.43 NOTCH1 PAX6
6 negative regulation of neuron differentiation GO:0045665 9.43 HOXA2 NOTCH1 PAX6
7 cell fate determination GO:0001709 9.4 HOXA2 PAX6
8 negative regulation of oligodendrocyte differentiation GO:0048715 9.37 NF1 NOTCH1
9 cell fate commitment GO:0045165 9.33 HOXA2 NOTCH1 PAX6
10 astrocyte differentiation GO:0048708 9.32 NOTCH1 PAX6
11 dorsal/ventral pattern formation GO:0009953 9.13 HOXA2 LRP4 PAX6
12 phosphatidylethanolamine acyl-chain remodeling GO:0036152 8.8 HRASLS2 PLA2G16 RARRES3

Molecular functions related to Poland Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 transferase activity, transferring acyl groups GO:0016746 8.92 HRASLS2 HRASLS5 PLA2G16 RARRES3

Sources for Poland Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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