MCID: PLG003
MIFTS: 15

Polg-Related Disorders malady

Genetic diseases (common) category

Summaries for Polg-Related Disorders

About this section
Sources:
20GeneReviews, 34MalaCards
See all sources

Fully expand this MalaCard

Download this MalaCard
MalaCards: Polg-Related Disorders is related to alpers syndrome and chronic progressive external ophthalmoplegia. An important gene associated with Polg-Related Disorders is POLG (polymerase (DNA directed), gamma). Related mouse phenotype embryogenesis.

GeneReviews summary for alpers

Aliases & Classifications for Polg-Related Disorders

About this section
Sources:
20GeneReviews, 21GeneTests
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases (common)


Aliases & Descriptions:

polg-related disorders 20 21


Related Diseases for Polg-Related Disorders

About this section
Sources:
18GeneCards, 19GeneDecks
See all sources

Diseases related to Polg-Related Disorders via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1alpers syndrome10.0POLG, C10orf2
2chronic progressive external ophthalmoplegia10.0POLG, C10orf2
3neuropathy10.0POLG, C10orf2
4spinocerebellar ataxia10.0C10orf2, POLG
5mitochondrial disorders9.9POLG, C10orf2

Graphical network of diseases related to Polg-Related Disorders:



Diseases related to polg-related disorders

Symptoms for Polg-Related Disorders

About this section

Drugs & Therapeutics for Polg-Related Disorders

About this section
Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Polg-Related Disorders

Drug clinical trials:

Search ClinicalTrials for Polg-Related Disorders

Search NIH Clinical Center for Polg-Related Disorders

Search CenterWatch for Polg-Related Disorders

Genetic Tests for Polg-Related Disorders

About this section
Sources:
21GeneTests
See all sources

Genetic tests related to Polg-Related Disorders:

id Genetic test Affiliating Genes
1 Polg-Related Disorders21 POLG

Anatomical Context for Polg-Related Disorders

About this section

Animal Models for Polg-Related Disorders or affiliated genes

About this section
Sources:
38MGI
See all sources

MGI Mouse Phenotypes related to Polg-Related Disorders:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053809.1POLG, C10orf2

Publications for Polg-Related Disorders

About this section
Sources:
53PubMed
See all sources

Articles related to Polg-Related Disorders:

idTitleAuthorsYear
1
POLG-related disorders: defects of the nuclear and mitochondrial genome interaction. (22084276)
2011
2
POLG-Related Disorders (20301791)
1993

Variations for Polg-Related Disorders

About this section

Expression for genes affiliated with Polg-Related Disorders

About this section
Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Polg-Related Disorders

Search GEO for disease gene expression data for Polg-Related Disorders.

Pathways for genes affiliated with Polg-Related Disorders

About this section

Compounds for genes affiliated with Polg-Related Disorders

About this section

GO Terms for genes affiliated with Polg-Related Disorders

About this section
Sources:
17Gene Ontology
See all sources

Cellular components related to Polg-Related Disorders according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1mitochondrial nucleoidGO:0426459.1POLG, C10orf2

Biological processes related to Polg-Related Disorders according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cell deathGO:0082199.1POLG, C10orf2
2mitochondrial DNA replicationGO:0062648.8POLG, C10orf2

Molecular functions related to Polg-Related Disorders according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protease bindingGO:0020209.1POLG, C10orf2

Products for genes affiliated with Polg-Related Disorders

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Polg-Related Disorders

About this section
4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet