MCID: PLG003
MIFTS: 13

Polg-Related Disorders malady

Genetic diseases (common) category

Summaries for Polg-Related Disorders

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MalaCards based summary: Polg-Related Disorders is related to mitochondrial dna depletion syndrome 4a and childhood myocerebrohepatopathy spectrum disorders. An important gene associated with Polg-Related Disorders is POLG (polymerase (DNA directed), gamma). Related mouse phenotype embryogenesis.

GeneReviews summary for alpers

Aliases & Classifications for Polg-Related Disorders

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Polg-Related Disorders, Aliases & Descriptions:

Name: Polg-Related Disorders 19 20


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases (common)


Related Diseases for Polg-Related Disorders

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Graphical network of diseases related to Polg-Related Disorders:



Diseases related to polg-related disorders

Symptoms for Polg-Related Disorders

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Drugs & Therapeutics for Polg-Related Disorders

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Drug clinical trials:

Search ClinicalTrials for Polg-Related Disorders

Search NIH Clinical Center for Polg-Related Disorders

Genetic Tests for Polg-Related Disorders

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Genetic tests related to Polg-Related Disorders:

id Genetic test Affiliating Genes
1 Polg-Related Disorders20 POLG

Anatomical Context for Polg-Related Disorders

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Animal Models for Polg-Related Disorders or affiliated genes

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MGI Mouse Phenotypes related to Polg-Related Disorders:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053809.1POLG, C10orf2

Publications for Polg-Related Disorders

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Articles related to Polg-Related Disorders:

idTitleAuthorsYear
1
POLG-related disorders: defects of the nuclear and mitochondrial genome interaction. (22084276)
2011
2
POLG-Related Disorders (20301791)
1993

Variations for Polg-Related Disorders

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Expression for genes affiliated with Polg-Related Disorders

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Search GEO for disease gene expression data for Polg-Related Disorders.

Pathways for genes affiliated with Polg-Related Disorders

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Compounds for genes affiliated with Polg-Related Disorders

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GO Terms for genes affiliated with Polg-Related Disorders

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Cellular components related to Polg-Related Disorders according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1mitochondrial nucleoidGO:00426459.1POLG, C10orf2

Biological processes related to Polg-Related Disorders according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cell deathGO:00082199.1POLG, C10orf2
2mitochondrial DNA replicationGO:00062648.8POLG, C10orf2

Molecular functions related to Polg-Related Disorders according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protease bindingGO:00020209.1POLG, C10orf2

Products for genes affiliated with Polg-Related Disorders

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Polg-Related Disorders

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet