MCID: PLG003
MIFTS: 15

Polg-Related Disorders malady

Genetic diseases (common) category
Download this MalaCard

Summaries for Polg-Related Disorders

About this section
Sources:
19GeneReviews, 33MalaCards
See all sources

Fully expand this MalaCard
MalaCards: Polg-Related Disorders is related to alpers syndrome and chronic progressive external ophthalmoplegia. An important gene associated with Polg-Related Disorders is POLG (polymerase (DNA directed), gamma). Related mouse phenotype embryogenesis.

GeneReviews summary for alpers

Aliases & Classifications for Polg-Related Disorders

About this section
Sources:
19GeneReviews, 20GeneTests
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases (common)


Aliases & Descriptions:

polg-related disorders 19 20


Related Diseases for Polg-Related Disorders

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Polg-Related Disorders via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1alpers syndrome10.0POLG, C10orf2
2chronic progressive external ophthalmoplegia10.0POLG, C10orf2
3neuropathy10.0POLG, C10orf2
4spinocerebellar ataxia10.0C10orf2, POLG
5mitochondrial disorders9.9POLG, C10orf2

Graphical network of diseases related to Polg-Related Disorders:



Diseases related to polg-related disorders

Symptoms for Polg-Related Disorders

About this section

Drugs & Therapeutics for Polg-Related Disorders

About this section
Sources:
42NIH Clinical Center, 6ClinicalTrials
See all sources

Drug clinical trials:

Search ClinicalTrials for Polg-Related Disorders

Search NIH Clinical Center for Polg-Related Disorders

Genetic Tests for Polg-Related Disorders

About this section
Sources:
20GeneTests
See all sources

Genetic tests related to Polg-Related Disorders:

id Genetic test Affiliating Genes
1 Polg-Related Disorders20 POLG

Anatomical Context for Polg-Related Disorders

About this section

Animal Models for Polg-Related Disorders or affiliated genes

About this section
Sources:
37MGI
See all sources

MGI Mouse Phenotypes related to Polg-Related Disorders:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053809.1POLG, C10orf2

Publications for Polg-Related Disorders

About this section
Sources:
52PubMed
See all sources

Articles related to Polg-Related Disorders:

idTitleAuthorsYear
1
POLG-related disorders: defects of the nuclear and mitochondrial genome interaction. (22084276)
2011
2
POLG-Related Disorders (20301791)
1993

Variations for Polg-Related Disorders

About this section

Expression for genes affiliated with Polg-Related Disorders

About this section
Sources:
2BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Polg-Related Disorders

Search GEO for disease gene expression data for Polg-Related Disorders.

Pathways for genes affiliated with Polg-Related Disorders

About this section

Compounds for genes affiliated with Polg-Related Disorders

About this section

GO Terms for genes affiliated with Polg-Related Disorders

About this section
Sources:
16Gene Ontology
See all sources

Cellular components related to Polg-Related Disorders according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1mitochondrial nucleoidGO:0426459.1POLG, C10orf2

Biological processes related to Polg-Related Disorders according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cell deathGO:0082199.1POLG, C10orf2
2mitochondrial DNA replicationGO:0062648.8POLG, C10orf2

Molecular functions related to Polg-Related Disorders according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protease bindingGO:0020209.1POLG, C10orf2

Products for genes affiliated with Polg-Related Disorders

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Polg-Related Disorders

About this section
4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet