MCID: PLY017
MIFTS: 49

Polyarteritis Nodosa malady

Rare diseases, Neuronal diseases, Cardiovascular diseases, Nephrological diseases, Bone diseases categories

Aliases & Classifications for Polyarteritis Nodosa

About this section
Sources:
10Disease Ontology, 45NIH Rare Diseases, 47Novoseek, 12DISEASES, 51Orphanet, 65UMLS, 36MeSH, 59SNOMED-CT, 29ICD9CM, 42NCIt, 66UMLS via Orphanet, 28ICD10 via Orphanet, 37MESH via Orphanet, 27ICD10
See all sources

Aliases & Descriptions for Polyarteritis Nodosa:

Name: Polyarteritis Nodosa 10 45 47 12 51 65 36
Pan 45 51
 
Küssmaul-Maier Disease 51
Periarteritis Nodosa 51


Classifications:



Characteristics (Orphanet epidemiological data):

51
polyarteritis nodosa:
Inheritance: Autosomal recessive,Not applicable; Prevalence: 1-9/100000 (Europe); Age of onset: All ages; Age of death: normal life expectancy


External Ids:

Disease Ontology10 DOID:9810
MeSH36 D010488
ICD9CM29 446.0
NCIt42 C26847
Orphanet51 767
UMLS via Orphanet66 C0031036
ICD10 via Orphanet28 M30.0
MESH via Orphanet37 D010488
ICD1027 M30.0

Summaries for Polyarteritis Nodosa

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NIH Rare Diseases:45 Polyarteritis nodosa is a serious blood vessel disease in which medium-sized arteries become swollen and damaged. it occurs when certain immune cells attack the affected arteries preventing vital oxygen and nourishment. signs and symptoms may include fever, fatigue, weakness, loss of appetite, weight loss, muscle and joint aches, and abdominal pain. the skin may show rashes, swelling, ulcers, and lumps. when nerve cells are involved numbness, pain, burning, and weakness may be present. polyarteritis nodosa can cause serious health complications including strokes, seizures, and kidney failure. treatment often includes steroids and other drugs to suppress the immune system. last updated: 1/16/2012

MalaCards based summary: Polyarteritis Nodosa, also known as pan, is related to retinitis and ischemic optic neuropathy, and has symptoms including renal insufficiency, nephropathy and cutis marmorata. An important gene associated with Polyarteritis Nodosa is CECR1 (Cat Eye Syndrome Chromosome Region, Candidate 1), and among its related pathways are African trypanosomiasis and Cell adhesion_Cell-matrix glycoconjugates. Affiliated tissues include skin, kidney and bone, and related mouse phenotypes are immune system and homeostasis/metabolism.

Related Diseases for Polyarteritis Nodosa

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Diseases in the Polyarteritis Nodosa family:

Systemic Polyarteritis Nodosa Secondary Polyarteritis Nodosa
Primary Polyarteritis Nodosa

Diseases related to Polyarteritis Nodosa via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 388)
idRelated DiseaseScoreTop Affiliating Genes
1retinitis31.0APOH, IL6
2ischemic optic neuropathy30.8CRP, IL6
3arthropathy30.5CRP, IL6, SELE
4artery disease30.5CRP, IL6, SELE
5myocardial infarction30.4CRP, IL6, MPO, SELL
6wegener granulomatosis30.2CRP, IL6, MPO, PRTN3, SELE
7hyperthyroidism30.2CRP, MEFV, MPO, PRTN3
8systemic lupus erythematosus30.0APOH, CRP, IL6, PRTN3
9rheumatoid arthritis29.9CRP, IL6, PRTN3, SELE
10asthma29.7IL6, MPO, SELE, SELL
11cutaneous polyarteritis nodosa11.3
12hepatitis11.1
13vasculitis11.0
14hepatitis b10.9
15microscopic polyangiitis10.9
16aneurysm10.9
17systemic polyarteritis nodosa10.9
18churg-strauss syndrome10.8
19antiphospholipid syndrome10.6
20hepatitis c10.6
21arthritis10.6
22purpura10.6
23primary polyarteritis nodosa10.6
24hepatitis c virus10.6
25kawasaki disease10.6
26polyarteritis nodosa, childhood-onset10.6
27crohn's disease10.6
28cerebritis10.6
29colitis10.6
30mononeuritis10.6
31mononeuritis multiplex10.5
32encephalopathy10.5
33leukemia10.5
34nephrosclerosis10.5
35sneddon syndrome10.5
36acute myocardial infarction10.5
37ulcerative colitis10.5
38temporal arteritis10.5
39retinal vasculitis10.5
40coronary aneurysm10.5
41intestinal perforation10.5
42intracranial aneurysm10.5
43ischemia10.5
44periostitis10.5
45periarteritis nodosa10.5
46autoimmune hepatitis10.4
47skin conditions10.4
48skin disease10.4
49central retinal artery occlusion10.4
50perinephritis10.4

Graphical network of the top 20 diseases related to Polyarteritis Nodosa:



Diseases related to polyarteritis nodosa

Symptoms for Polyarteritis Nodosa

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Symptoms:

 51 (show all 60)
  • cutis marmorata/marbled skin/livedo
  • cutaneous rash
  • purpura/petichiae
  • acute abdominal pain/colic
  • asthma/bronchospasm
  • cardiomyopathy/hypertrophic/dilated
  • acute arterial hypertension/hypertensive crisis
  • arterial stenosis/occlusion
  • edema of the legs/lower limbs
  • arterial aneurism (excluding aorta)
  • vascularitis/vasculitides/arteritis
  • acute ischemia of the lower limbs
  • renal disease/nephropathy
  • renal failure
  • testes inflammation/orchitis
  • peripheral neuropathy
  • neuritis/polyneuritis/multineuritis
  • facial pain/cephalalgia/migraine
  • pyramidal syndrome
  • hemiplegia/diplegia/hemiparesia/limb palsy
  • paresthesia/dysesthesia/hypoesthesia/anesthesia/numbness
  • myalgia/muscular pain
  • articular/joint pain/arthralgia
  • weight loss/loss of appetite/break in weight curve/general health alteration
  • fever/chilling
  • biological inflammatory syndrome/increased erythrocyte sedimentation rate/crp
  • chronic skin infection/ulcerations/ulcers/cancrum
  • urticaria
  • follicular/erythematous/edematous papules/milium
  • gastrointestinal bleeding/hemorrhage/hematemesis/melena/rectorrhagia
  • intestinal perforation
  • hepatitis/icterus/cholestasis
  • cardiac rhythm disorder/arrhythmia
  • angor pectoris/myocardial infarction
  • mesenteric/intestinal infarction
  • gangrena/necrosis
  • seizures/epilepsy/absences/spasms/status epilepticus
  • psychic/behavioural troubles
  • hyperleukocytosis/leukocytosis
  • chronic uveitis/blepharitis/episcleritis/scleritis/conjonctivitis/keratitis
  • retinal detachment
  • retinal vascular anomalies/retinal telangiectasia
  • ascitis
  • malabsorption/chronic diarrhea/steatorrhea
  • biliary/gallbladder stones/lithiasis/cholecystitis
  • hemobilia
  • pancreatitis
  • pericardium anomalies/pericarditis/absence/cysts/pericardial effusion
  • heart/cardiac failure
  • acrocyanosis/raynaud's phenomenon/vasomotor disorders
  • arterial embolism/thrombosis
  • acute ischemic syndrome
  • ureteral stenosis/narrowing
  • encephalitis
  • extrapyramidal syndrome
  • myositis
  • osteolysis/osteoclasia/bone destruction/erosions
  • osteomyelitis/osteitis/periostitis/spondylodisciitis
  • arthritis/synovitis/synovial proliferation
  • autoimmunity/autoimmune reaction/autoantibodies

HPO human phenotypes related to Polyarteritis Nodosa:

(show all 51)
id Description Frequency HPO Source Accession
1 renal insufficiency hallmark (90%) HP:0000083
2 nephropathy hallmark (90%) HP:0000112
3 cutis marmorata hallmark (90%) HP:0000965
4 skin rash hallmark (90%) HP:0000988
5 polyneuropathy hallmark (90%) HP:0001271
6 hypertrophic cardiomyopathy hallmark (90%) HP:0001639
7 weight loss hallmark (90%) HP:0001824
8 subcutaneous hemorrhage hallmark (90%) HP:0001933
9 abdominal pain hallmark (90%) HP:0002027
10 migraine hallmark (90%) HP:0002076
11 asthma hallmark (90%) HP:0002099
12 aneurysm hallmark (90%) HP:0002617
13 vasculitis hallmark (90%) HP:0002633
14 arthralgia hallmark (90%) HP:0002829
15 myalgia hallmark (90%) HP:0003326
16 paresthesia hallmark (90%) HP:0003401
17 abnormality of temperature regulation hallmark (90%) HP:0004370
18 hemiplegia/hemiparesis hallmark (90%) HP:0004374
19 abnormal pyramidal signs hallmark (90%) HP:0007256
20 edema of the lower limbs hallmark (90%) HP:0010741
21 hypertensive crisis hallmark (90%) HP:0100735
22 orchitis hallmark (90%) HP:0100796
23 behavioral abnormality typical (50%) HP:0000708
24 urticaria typical (50%) HP:0001025
25 seizures typical (50%) HP:0001250
26 coronary artery disease typical (50%) HP:0001677
27 leukocytosis typical (50%) HP:0001974
28 gastrointestinal hemorrhage typical (50%) HP:0002239
29 gastrointestinal infarctions typical (50%) HP:0005244
30 arrhythmia typical (50%) HP:0011675
31 gangrene typical (50%) HP:0100758
32 skin ulcer typical (50%) HP:0200042
33 ureteral stenosis occasional (7.5%) HP:0000071
34 retinal detachment occasional (7.5%) HP:0000541
35 acrocyanosis occasional (7.5%) HP:0001063
36 arthritis occasional (7.5%) HP:0001369
37 ascites occasional (7.5%) HP:0001541
38 congestive heart failure occasional (7.5%) HP:0001635
39 abnormality of the pericardium occasional (7.5%) HP:0001697
40 pancreatitis occasional (7.5%) HP:0001733
41 malabsorption occasional (7.5%) HP:0002024
42 abnormality of extrapyramidal motor function occasional (7.5%) HP:0002071
43 encephalitis occasional (7.5%) HP:0002383
44 osteomyelitis occasional (7.5%) HP:0002754
45 osteolysis occasional (7.5%) HP:0002797
46 autoimmunity occasional (7.5%) HP:0002960
47 arterial thrombosis occasional (7.5%) HP:0004420
48 abnormality of the retinal vasculature occasional (7.5%) HP:0008046
49 inflammatory abnormality of the eye occasional (7.5%) HP:0100533
50 myositis occasional (7.5%) HP:0100614
51 hemobilia occasional (7.5%) HP:0100762

Drugs & Therapeutics for Polyarteritis Nodosa

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Drugs for Polyarteritis Nodosa (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 22)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Mycophenolate mofetilapproved, investigationalPhase 4864128794-94-55281078
Synonyms:
115007-34-6
128794-94-5
140401-05-4
2-Morpholinoethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (e)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-morpholin-4-ylethyl (4E)-6-[4-hydroxy-7-methyl-6-(methyloxy)-3-oxo-1,3-dihydro-2-benzofuran-5-yl]-4-methylhex-4-enoate
2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl -3-oxo-5-isobenzofuranyl)-4-methyl-, 2-(4-morpholinyl)ethyl ester, (4E)
AC-1562
AC1NQXZW
AC1Q6O6X
AR-1J6939
BB_NC-2566
C07908
C23H31NO7
CHEMBL1456
CID5281078
CellCept
CellCept, RS 61443, TM-MMF, Mycophenolate mofetil
Cellcept
Cellcept (TN)
D00752
DB00688
HMS2090A03
 
HSDB 7436
I01-0898
I06-1947
LS-172272
LS-75572
ME-MPA
MMF
MMF CellCept(TM)
MolPort-000-883-800
Munoloc
Mycophenolate Mofetil
Mycophenolate mofetil (JAN/USAN)
Mycophenolic acid morpholinoethyl ester
Mycophenylate mofetil
NCGC00159459-02
NCGC00159459-03
NSC724229
R-99
RS 61443
RS-61443
RS-61443-190
S1501_Selleck
TL8000648
TM-MMF
UNII-9242ECW6R0
ZINC21297660
mycophenolate mofetil
2
Mycophenolic acidapprovedPhase 486424280-93-1446541
Synonyms:
(e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
Acide mycophenolique
Acido micofenolico
Acidum mycophenolicum
Melbex
 
Micofenolico acido
Mycophenoic acid
Mycophenolate
Mycophenolic Acid
Mycophenolsaeure
Myfortic
3
PrednisoloneapprovedPhase 4103350-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
Flo-pred
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
MLS001304083
 
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
Millipred
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Omnipred
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
4
AzathioprineapprovedPhase 4, Phase 3145446-86-62265
Synonyms:
446-86-6
55774-33-9 (hydrochloride salt)
6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine
6-((1-Methyl-4-nitroimidazol-5-yl)thio)purine
6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine
6-(1'-Methyl-4'-nitro-5'-imidazolyl)mercaptopurine
6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine
6-(1-Methyl-4-nitroimidazol-5-ylthio)purin
6-(1-Methyl-4-nitroimidazol-5-ylthio)purin [Czech]
6-(1-Methyl-p-nitro-5-imidazolyl)-thiopurine
6-(1-Methyl-p-nitro-5-imidazolyl)thiopurine
6-(3-Methyl-5-nitro-3H-imidazol-4-ylsulfanyl)-7H-purine
6-(3-methyl-5-nitroimidazol-4-yl)sulfanyl-7H-purine
6-(Methyl-p-nitro-5-imidazolyl)-thiopurine
6-(Methyl-p-nitro-5-imidazolyl)thiopurine
6-({4-nitro-1-methyl-1H-imidazol-5-yl}sulfanyl)-7H-purine
6-1'-Methyl,4'-nitro,5'-imidazolyl mercaptopurine
6-[(1-Methyl-4-nitroimidazol-5-yl)- thio] purine
6-[(1-Methyl-4-nitroimidazol-5-yl)thio]purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-Purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-7H-purine
6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-9H-purine
A 4638
A2593_SIAL
A4638_SIAL
A4638_SIGMA
AB00443544
AB00443544-03
AC-4230
AC1L1DAL
AC1Q3Z1F
AI-981/34845012
AI3-50290
Azamun
Azamun [Czech]
Azanin
Azasan
Azasan (TN)
Azasan, Imuran, Azamun, BW-57-322, NSC-39084, Azathioprine
Azathioprin
Azathioprine
Azathioprine (JP15/USP/INN)
Azathioprine Sodium
Azathioprine [USAN:INN:BAN:JAN]
Azathioprine sodium
Azathioprinum
Azathioprinum [INN-Latin]
Azathiopurine
Azatioprin
Azatioprina
Azatioprina [INN-Spanish]
Azothioprine
B. W. 57-322
BPBio1_000054
BRD-K32821942-001-05-6
BRD-K60324116-001-01-5
BSPBio_000048
BSPBio_001876
BW 57-322
BW 57322
BW-57-322
C06837
C9H7N7O2S
CAS-446-86-6
CBDivE_013132
CCRIS 62
CHEBI:2948
CHEMBL1542
CID2265
CPD000427366
Ccucol
ChemDiv1_002659
Cytostatics
D00238
DB00993
DivK1c_000586
EINECS 207-175-4
EU-0100027
FT-0083532
HMS1568C10
 
HMS1920E17
HMS2091K19
HMS501N08
HMS594I19
HSDB 7084
IDI1_000586
Immuran
Imuran
Imuran (TN)
Imuran (tn)
Imurek
Imurel
KBio1_000586
KBio2_000464
KBio2_002427
KBio2_003032
KBio2_004995
KBio2_005600
KBio2_007563
KBio3_001376
KBio3_002906
KBioGR_000646
KBioGR_002427
KBioSS_000464
KBioSS_002433
LS-123
Lopac-A-4638
Lopac0_000027
MLS001049307
Methylnitroimidazolylmercaptopurine
MolPort-000-745-914
MolPort-000-764-262
MolPort-003-665-485
Muran
NCGC00015060-01
NCGC00015060-02
NCGC00015060-04
NCGC00015060-12
NCGC00090836-01
NCGC00090836-02
NCGC00090836-03
NCGC00090836-04
NCGC00090836-05
NCGC00090836-06
NCGC00094593-01
NCGC00094593-02
NCGC00094593-03
NCI-C03474
NINDS_000586
NSC 39084
NSC-39084
NSC39084
Oprea1_375441
Oprea1_533384
Oprea1_633462
Prestwick0_000094
Prestwick1_000094
Prestwick2_000094
Prestwick3_000094
Prestwick_41
S1721_Selleck
SAM002589938
SDCCGMLS-0065415.P001
SMR000427366
SPBio_000255
SPBio_001987
SPECTRUM1500133
STK831906
STOCK1S-20293
STOCK1S-27186
Spectrum2_000068
Spectrum3_000308
Spectrum4_000243
Spectrum5_000848
Spectrum_000064
Thiopurine 6-(1-methyl-4-nitroimidazol-5-yl)
UNII-MRK240IY2L
WLN: T56 BM DN FN HNJ IS- ET5N CNJ A1 DNW
ZINC04258316
[Methyl(nitroimidazolyl)mercaptopurine]
azathioprine
azatiopr in
cMAP_000046
5
PrednisoneapprovedPhase 4, Phase 2120853-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
Juvason
 
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Perrigo Prednisone
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rayos
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone
6
Cyclophosphamideapproved, investigationalPhase 4, Phase 2252550-18-0, 6055-19-22907
Synonyms:
(+-)-Cyclophosphamide
(-)-Cyclophosphamide
(RS)-Cyclophosphamide
1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine
1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin
2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
4-Hydroxy-cyclophosphan-mamophosphatide
50-18-0
60007-95-6
6055-19-2 (monohydrate)
75526-90-8
AC1L1EQQ
AI3-26198
ASTA
ASTA B518
Asta B 518
B 518
B-518
BRN 0011744
BSPBio_002099
Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
C 0768
C07888
C7H15Cl2N2O2P
CB 4564
CB-4564
CCRIS 188
CHEBI:4027
CHEMBL32520
CHEMBL88
CID2907
CP
CPA
CTX
CY
Ciclofosfamida
Ciclofosfamida [INN-Spanish]
Ciclofosfamide
Ciclophosphamide
Ciclophosphamide [INN]
Clafen
Claphene
Cycloblastin
Cyclophosphamid
Cyclophosphamide
Cyclophosphamide (INN)
Cyclophosphamide (TN)
Cyclophosphamide (anhydrous form)
Cyclophosphamide (anhydrous)
Cyclophosphamide Monohydrate
Cyclophosphamide Sterile
Cyclophosphamide anhydrous
Cyclophosphamide, (+-)-Isomer
Cyclophosphamides
Cyclophosphamidum
Cyclophosphamidum [INN-Latin]
Cyclophosphan
Cyclophosphane
Cyclophosphanum
Cyclophosphoramide
Cyclostin
Cyklofosfamid
Cyklofosfamid [Czech]
Cytophosphan
Cytophosphane
Cytoxan
Cytoxan (TN)
Cytoxan Lyoph
D,L-Cyclophosphamide
D07760
DB00531
 
DivK1c_000246
EINECS 200-015-4
EU-0100238
Endoxan
Endoxan R
Endoxan-Asta
Endoxana
Endoxanal
Endoxane
Enduxan
Genoxal
HMS2090A12
HSDB 3047
Hexadrin
IDI1_000246
KBio1_000246
KBio2_001338
KBio2_003906
KBio2_006474
KBio3_001319
KBioGR_000888
KBioSS_001338
LS-1302
LS-99787
Ledoxina
Lopac-C-0768
Lopac0_000238
Lyophilized Cytoxan
Mitoxan
MolPort-001-783-420
N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
NCGC00015209-01
NCGC00015209-03
NCGC00015209-06
NCGC00091741-02
NCGC00091741-03
NCI-C04900
NCI60_002097
NINDS_000246
NSC 26271
NSC-26271
NSC26271
NSC273033
NSC273034
Neosar
Occupation, cyclophosphamide exposure
Procytox
RCRA waste no. U058
Rcra Waste Number U058
Rcra waste number U058
Revimmune
S1217_Selleck
SK 20501
SPBio_001071
STK177249
STOCK2S-91217
Semdoxan
Sendoxan
Senduxan
Spectrum2_001146
Spectrum3_000370
Spectrum4_000304
Spectrum5_000795
Spectrum_000858
UNII-6UXW23996M
WLN: T6MPOTJ BO BN2G2G
Zyklophosphamid
Zyklophosphamid [German]
bis(2-Chloroethyl)phosphami de cyclic propanolamide
bis(2-Chloroethyl)phosphamide cyclic propanolamide ester
cyclophosphamide
7
MethotrexateapprovedPhase 4, Phase 213871959-05-2, 59-05-2126941
Synonyms:
4-amino-10-methylfolic acid
4-amino-N(10)-Methylpteroylglutamic acid
Abitrexate
Amethopterin
Amethopterine
Antifolan
Arbitrexate
Emtexate
Folex
HDMTX
L-Amethopterin
Ledertrexate
MTX
Metatrexan
Methopterin
Methotextrate
 
Methotrate
Methotrexat
Methotrexate
Methotrexate Sodium
Methotrexatum
Methylaminopterin
Methylaminopterinum
Metoject
Metotrexato
Mexate
Méthotrexate
N-Bismethylpteroylglutamic Acid
N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
Otrexup
Rasuvo
Rheumatrex
Rheumatrex Dose Pack
Trexall
8
MethylprednisoloneapprovedPhase 4103383-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
A-methapred
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Depo-medrol
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Solu-medrol
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
9Prednisolone phosphatePhase 41033
10Prednisolone hemisuccinatePhase 41033
11Methylprednisolone acetatePhase 41033
12Methylprednisolone HemisuccinatePhase 41033
13Prednisolone acetatePhase 41033
14
Lamivudineapproved, investigationalPhase 2575134678-17-460825
Synonyms:
(+/-) (Cis)-1-[2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
(+/-)-3TC
(+/-)-BCH-189
(+/-)-SddC
(-)-(2'R,5'S)-1-[2'-Hydroxymethyl-5'-(1,3-oxathiolanyl)]cytosine
(-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine
(-)-1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
(-)-2'-Deoxy-3'-thiacytidine
(-)-BCH 189
(-)-BCH-189
(-)-SddC
(-)-beta-L-2',3'-Dideoxy-3'-thiacytidine
(-)NGPB-21
(2R,cis)-4-amino-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one
.beta.-L-(-)-2',3'-dideoxy-3'-thiacytidine & Sho-Saiko-To
134678-17-4
2',3' Dideoxy 3' thiacytidine
2',3'-Dideoxy-3'-thiacytidine
2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (+/-) (Cis)
2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S)
2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S) & Galanthus Nivalis Agglutinin (GNA)
2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S) & Hippeastrum hybrid agglutinin( HHA)
3'-Thia-2',3'-dideoxycytidine
3-TC
3TC
3TC & GNA
3TC & SST
3TC (AIDS INITIATIVE) (AIDS INITIATIVE)
3TC and NV-01
3TC, Zeffix, Heptovir, Epivir, Epivir-HBV, Lamivudine
4-Amino-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone
4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
480434-79-5
AC-1416
AC1L1TZZ
AC1Q6C34
BCH 189
BCH-189
BCH-790
BCH189
BIDD:GT0033
Bio-0652
C07065
C8H11N3O3S
CCRIS 9274
CHEBI:133986
CHEMBL141
CID60825
CPD000466319
D00353
D019259
DB00709
 
DRG-0126
DTHC
Epivir
Epivir (TN)
Epivir HBV
Epivir(TM)
Epivir-HBV
Epzicom
FT-0082667
GG-714
GR 109714 X
GR 109714X
GR-109714X
GR109714X
HHA & 3TC
HHA & Lamivudine
HMS2051D21
HSDB 7155
Hepitec
Heptivir
Heptodin
Heptovir
L0217
LMV
LS-2107
Lamivir
Lamivudin
Lamivudina
Lamivudine
Lamivudine & GNA
Lamivudine (JAN/USP/INN)
Lamivudine [USAN:BAN:INN]
Lamivudine [USAN:INN:BAN]
Lamivudine [Usan:Ban:Inn]
Lamivudine, (2S-cis)-Isomer
Lamivudinum
MLS000759424
MLS001424097
MolPort-002-507-347
NCGC00159341-03
NCGC00159341-04
NSC620753
S1706_Selleck
SAM001246582
SAM002589994
SMR000466319
STK801940
UNII-2T8Q726O95
ZINC00012346
Zeffix
Zefix
beta-L-2',3'-Dideoxy-3'-thiacytidine
beta-L-3'-Thia-2',3'-dideoxycytidine
lamivudine
15
Folic Acidapproved, nutraceuticalPhase 2285159-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic Acid
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
 
Folsaeure
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
16Vitamin B ComplexPhase 22775
17FolateNutraceuticalPhase 22851
18Vitamin B9NutraceuticalPhase 22851
19Folinic AcidNutraceuticalPhase 22498
20lenograstim1108
21Antilymphocyte Serum376
22Cyclosporins849

Interventional clinical trials:

(show all 20)
idNameStatusNCT IDPhase
1Treatment of Necrotizing Vasculitides for Patients Older Than 65 YearsCompletedNCT00307671Phase 4
2CHUSPAN PAN BP Treatment of Polyarteritis Nodosa and Microscopic Polyangiitis Without Poor-Prognosis FactorsActive, not recruitingNCT00400075Phase 4
3Association Corticosteroid/Azathioprine in Microscopic Polyangiitis/ Polyarteritis Nodosa or Eosinophilic Granulomatosis With Polyangiitis (Churg Strauss Syndrome)CompletedNCT00647166Phase 3
4Lamivudine for Chronic Hepatitis BCompletedNCT00001457Phase 2
5Steroids and Methotrexate to Treat Systemic VasculitisCompletedNCT00001256Phase 2
6Cyclophosphamide Versus Methotrexate for Remission Maintenance in Systemic Necrotizing VasculitidesActive, not recruitingNCT00751517Phase 2
7Hematopoietic Stem Cell Support in VasculitisRecruitingNCT00278512Phase 1
8Educational Needs of Patients With Systemic VasculitisCompletedNCT02190929
9Vasculitis Illness Perception (VIP) StudyCompletedNCT02190916
10Reproductive Health in Men and Women With VasculitisCompletedNCT02176070
11Impact of Vasculitis on Employment and IncomeCompletedNCT02476292
12Cyclophosphamide and Prednisone Followed by Methotrexate To Treat VasculitidesCompletedNCT00001473
13Determining Disease Activity Biomarkers in Individuals With Polyarteritis NodosaRecruitingNCT00315406
14American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) Diagnostic and Classification Criteria for Primary Systemic VasculitisRecruitingNCT01066208
15Pediatric Vasculitis InitiativeRecruitingNCT02006134
16One-Time DNA Study for VasculitisRecruitingNCT01241305
17Vasculitis Pregnancy RegistryRecruitingNCT02593565
18Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune DiseasesActive, not recruitingNCT00006055
19Steroid-Induced Osteoporosis in the Pediatric Population - Canadian Incidence StudyActive, not recruitingNCT01663129
20VCRC Patient Contact Registry Patient-Reported Data Validation StudyEnrolling by invitationNCT02190942

Search NIH Clinical Center for Polyarteritis Nodosa


Cochrane evidence based reviews: Polyarteritis Nodosa

Genetic Tests for Polyarteritis Nodosa

About this section

Anatomical Context for Polyarteritis Nodosa

About this section

MalaCards organs/tissues related to Polyarteritis Nodosa:

33
Skin, Kidney, Bone, Heart, Liver, Eye, Testes

Animal Models for Polyarteritis Nodosa or affiliated genes

About this section

MGI Mouse Phenotypes related to Polyarteritis Nodosa:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053877.2CRP, IL6, MEFV, MPO, PRTN3, SELE
2MP:00053766.5APOH, CRP, IL6, MEFV, MPO, SELE

Publications for Polyarteritis Nodosa

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Articles related to Polyarteritis Nodosa:

(show top 50)    (show all 671)
idTitleAuthorsYear
1
Flow diversion in vasculitic intracranial aneurysms? Repair of giant complex cavernous carotid aneurysm in polyarteritis nodosa using Pipeline embolization devices: first reported case. (26041095)
2015
2
Ureteric vasculitis, an unusual presentation of polyarteritis nodosa: a case report. (25925589)
2015
3
Polyarteritis nodosa presented as a dilatation of the intrahepatic bile duct. (25368854)
2014
4
Abdominal pain developing from a polyarteritis nodosa-induced hepatic aneurysm. (25599794)
2014
5
Young male patient diagnosed with cutaneous polyarteritis nodosa successfully treated with etanercept. (24981320)
2014
6
Mutant adenosine deaminase 2 in a polyarteritis nodosa vasculopathy. (24552285)
2014
7
Polyarteritis nodosa in childhood: recognition of early dermatologic signs may prevent morbidity. (23937359)
2014
8
Polyarteritis nodosa complicated by posterior reversible encephalopathy syndrome: a case report. (25349926)
2014
9
Necrosis of the tongue as first symptom of Polyarteritis Nodosa (PAN): unusual presentation of a rare disease in children. (21136262)
2013
10
Coronary Artery Bypass Grafting in a Patient with Polyarteritis Nodosa Presenting with Acute Myocardial Infarction and Multiple Coronary Aneurysms. (23995351)
2013
11
Macular arteritis: a pole of the spectrum of cutaneous polyarteritis nodosa? (22995948)
2013
12
Polyarteritis nodosa presenting as acute myocardial infarction in a young man: importance of invasive angiography. (23661639)
2013
13
Remission induced by infliximab in a childhood polyarteritis nodosa refractory to conventional immunosuppression and rituximab. (24388782)
2013
14
Comments on sudden death due to polyarteritis nodosa. (22052059)
2012
15
The usefulness of 3D-CT angiography in polyarteritis nodosa. (22687865)
2012
16
Cutaneous polyarteritis nodosa associated with HLA-B39-positive undifferentiated spondyloarthritis in a Japanese patient. (22270344)
2012
17
Polyarteritis nodosa and SjAPgren's syndrome: overlap syndrome. (20480165)
2012
18
Cutaneous polyarteritis nodosa induced by Mycobacterium tuberculosis. (22035185)
2012
19
A case of systemic polyarteritis nodosa involving bronchial artery. (21319600)
2010
20
Classic polyarteritis nodosa presenting with rapidly progressive renal insufficiency. (20875386)
2010
21
Acute Myocardial Infarction due to Polyarteritis Nodosa in a Young Female Patient. (20421961)
2010
22
Fulminant polyarteritis nodosa associated with acute myeloid leukaemia resulted in bilateral lower leg amputation. (19553374)
2009
23
Hepatobiliary scintigraphy in vasculitis of the gallbladder as a manifestation of polyarteritis nodosa: a case report. (20062624)
2009
24
Cutaneous polyarteritis nodosa treated with intravenous immunoglobulins. (18031500)
2008
25
SIR 2006 annual meeting film panel case: polyarteritis nodosa in upper extremity arteries. (17804766)
2007
26
A case of polyarteritis nodosa complicated by left central retinal artery occlusion, ischemic optic neuropathy, and retinal vasculitis. (16575492)
2007
27
A case of recurrent abdominal bleeding due to polyarteritis nodosa despite immunosuppressive therapy. (18092276)
2007
28
Lymphoplasmacytic lymphoma associated with polyradiculoneuritis and cryoglobulinemia mimicking polyarteritis nodosa. (17287105)
2007
29
Polyarteritis nodosa: successful diagnostic imaging utilizing pulsed and color Doppler ultrasonography and computed tomography angiography. (16222527)
2006
30
Hemobilia from ruptured hepatic artery aneurysm in polyarteritis nodosa. (16646571)
2006
31
Polyarteritis nodosa and cryoglobulinemic glomerulonephritis related to chronic hepatitis C. (16775442)
2006
32
Successful pregnancy complicated by microscopic polyarteritis nodosa. (15960155)
2005
33
Short-term corticosteroids then lamivudine and plasma exchanges to treat hepatitis B virus-related polyarteritis nodosa. (15188337)
2004
34
Successful response to infliximab in a patient with undifferentiated spondyloarthropathy coexisting with polyarteritis nodosa-like cutaneous vasculitis. (14740443)
2003
35
Vasculitis: Wegener granulomatosis, Churg-Strauss syndrome, microscopic polyangiitis, polyarteritis nodosa, and Takayasu arteritis. (12418444)
2002
36
Duodenal necrosis as the presenting manifestation of polyarteritis nodosa. (12189461)
2002
37
Transient and partial effect of high-dose intravenous immunoglobulin in polyarteritis nodosa. (11586025)
2001
38
Treatment of polyarteritis nodosa, microscopic polyangiitis, and Churg-Strauss syndrome: where do we stand? (11263763)
2001
39
Hepatitis B-related polyarteritis nodosa complicated by pulmonary hemorrhage. (11348978)
2001
40
Spontaneous perirenal hematoma as the initial manifestation of polyarteritis nodosa and long-term follow-up without treatment. (10867546)
2000
41
Sensory ataxic dominant neuropathy associated with polyarteritis nodosa. (11030213)
2000
42
Childhood polyarteritis nodosa presenting as a relapsing movement disorder. (10685835)
2000
43
A case of cutaneous polyarteritis nodosa associated with ulcerative colitis. (10777260)
2000
44
Dynamic pattern of endothelial cell adhesion molecule expression in muscle and perineural vessels from patients with classic polyarteritis nodosa. (9506571)
1998
45
Antineutrophil cytoplasm antibodies in systemic polyarteritis nodosa with and without hepatitis B virus infection and Churg-Strauss syndrome--62 patients. (7901412)
1993
46
Distinct responses of interleukin-6 and other laboratory parameters to treatment in a patient with polyarteritis nodosa--a case report. (1350713)
1992
47
Giant cell (temporal) arteritis following polyarteritis nodosa. (2567193)
1989
48
Cutaneous polyarteritis nodosa. Report of a case associated with Crohn's disease. (6132589)
1983
49
MONONEURITIS MULTIPLEX IN POLYARTERITIS NODOSA. (14144116)
1964
50
MONONEURITIS MULTIPLEX IN POLYARTERITIS NODOSA. (14045124)
1963

Variations for Polyarteritis Nodosa

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Clinvar genetic disease variations for Polyarteritis Nodosa:

5
id Gene Variation Type Significance SNP ID Assembly Location
1CECR1NM_001282227.1(CECR1): c.1232A> G (p.Tyr411Cys)single nucleotide variantPathogenicrs376785840GRCh37Chr 22, 17662794: 17662794
2CECR1NM_001282227.1(CECR1): c.200C> A (p.Ala67Asp)single nucleotide variantPathogenicrs587777240GRCh37Chr 22, 17688177: 17688177
3CECR1NM_001282227.1(CECR1): c.14G> C (p.Gly5Ala)single nucleotide variantPathogenicrs200930463GRCh37Chr 22, 17690428: 17690428
4CECR1NM_001282227.1(CECR1): c.210C> G (p.His70Gln)single nucleotide variantPathogenicrs587777241GRCh37Chr 22, 17688167: 17688167
5CECR1NM_001282227.1(CECR1): c.380G> A (p.Arg127Gln)single nucleotide variantPathogenicrs77563738GRCh37Chr 22, 17687997: 17687997
6CECR1NM_001282227.1(CECR1): c.13G> A (p.Gly5Arg)single nucleotide variantPathogenicrs202134424GRCh37Chr 22, 17690429: 17690429
7CECR1NM_001282227.1(CECR1): c.626C> T (p.Pro209Leu)single nucleotide variantPathogenicrs148936893GRCh38Chr 22, 17203564: 17203564
8CECR1NM_001282227.1(CECR1): c.14G> T (p.Gly5Val)single nucleotide variantPathogenicrs200930463GRCh37Chr 22, 17690428: 17690428
9CECR1NM_001282227.1(CECR1): c.665G> C (p.Trp222Ser)single nucleotide variantPathogenicrs587777242GRCh37Chr 22, 17672663: 17672663

Expression for genes affiliated with Polyarteritis Nodosa

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Search GEO for disease gene expression data for Polyarteritis Nodosa.

Pathways for genes affiliated with Polyarteritis Nodosa

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Pathways related to Polyarteritis Nodosa according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3IL6, SELE
29.3SELE, SELL
3
Show member pathways
9.1CRP, IL6, MPO
4
Show member pathways
8.1IFNA2, IL6, PRTN3, SELE, SELL

GO Terms for genes affiliated with Polyarteritis Nodosa

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Cellular components related to Polyarteritis Nodosa according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056156.6APOH, CECR1, CRP, IFNA2, IL6, MPO

Biological processes related to Polyarteritis Nodosa according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of lipid storageGO:001088810.1CRP, IL6
2acute-phase responseGO:000695310.0CRP, IL6
3positive regulation of tyrosine phosphorylation of Stat3 proteinGO:00425179.9IFNA2, IL6
4response to yeastGO:00018789.9IL6, MPO
5inflammatory responseGO:00069548.5CRP, IFNA2, IL6, MEFV, SELE
6blood coagulationGO:00075967.8APOH, IFNA2, PRTN3, SELE, SELL

Molecular functions related to Polyarteritis Nodosa according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1heparin bindingGO:00082018.4APOH, CECR1, MPO, SELL

Sources for Polyarteritis Nodosa

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet