PCOS
MCID: PLY011
MIFTS: 68

Polycystic Ovary Syndrome (PCOS) malady

Endocrine diseases category

Summaries for Polycystic Ovary Syndrome

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42NIH Rare Diseases, 33MedlinePlus, 63Wikipedia, 46OMIM, 32MalaCards
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MedlinePlus:33 Polycystic ovary syndrome (pcos) happens when a woman's ovaries or adrenal glands produce more male hormones than normal. one result is that cysts (fluid-filled sacs) develop on the ovaries. women who are obese are more likely to have polycystic ovary syndrome. symptoms of pcos include: infertility pelvic pain excess hair growth on the face, chest, stomach, thumbs, or toes baldness or thinning hair acne, oily skin, or dandruff patches of thickened dark brown or black skin women with pcos are at higher risk of diabetes, metabolic syndrome, heart disease, and high blood pressure. medicines can help control the symptoms. birth control pills help women have normal periods, reduce male hormone levels, and clear acne. other medicines can reduce hair growth and control blood pressure and cholesterol. there is no cure. nih: national institute of child health and human development

MalaCards: Polycystic Ovary Syndrome, also known as polycystic ovaries, is related to obesity and hyperandrogenism. An important gene associated with Polycystic Ovary Syndrome is SULT2A1 (sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1), and among its related pathways are Ovarian steroidogenesis and Adipogenesis. The drug urofollitropin and the compounds testosterone and cholesterol have been mentioned in the context of this disorder. Affiliated tissues include ovary, heart and skin, and related mouse phenotypes are homeostasis/metabolism and endocrine/exocrine gland.

NIH Rare Diseases:42 Polycystic ovarian syndrome (pcos) is a health problem that can affect a woman's menstrual cycle, ability to have children, hormones, heart, blood vessels, and appearance. women with this condition typically have high levels of  hormones called androgens, missed or irregular periods, and many small cysts in their ovaries. the cause of pcos is unknown, but probably involves a combination of genetic and environmental factors. treatment for pcos may involve birth control pills and medications for diabetes and infertility. medicines called anti-androgens are also used to speed the growth of hair and clear acne. last updated: 11/10/2008

Wikipedia:63 Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders among females. PCOS has a... more...

Description from OMIM:46 184700

Aliases & Classifications for Polycystic Ovary Syndrome

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8Disease Ontology, 10DISEASES, 44Novoseek, 33MedlinePlus, 60UMLS, 42NIH Rare Diseases, 56SNOMED-CT, 39NCIt, 46OMIM, 27ICD9CM, 34MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Endocrine diseases


Aliases & Descriptions:

polycystic ovary syndrome 8 10 44 33 60
polycystic ovaries 8 44
pcos 8 42
polycystic ovarian syndrome 42
polycystic ovarian disease 8
stein-leventhal syndrome 8
stein-leventhal synd. 8
multicystic ovaries 8
polycystic ovary 8


External Ids:

Disease Ontology8 DOID:11612
NCIt39 C26862
OMIM46 184700
ICD9CM27 256.4
MeSH34 D011085
ICD1025 E28.2

Related Diseases for Polycystic Ovary Syndrome

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17GeneCards, 18GeneDecks
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Diseases in the Polycystic Ovary Syndrome family:

Polycystic Ovary Syndrome 1

Diseases related to Polycystic Ovary Syndrome via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 245)
idRelated DiseaseScoreTop Affiliating Genes
1obesity31.9CAPN10, LSL, RBP4, GHRL, SHBG, IGFBP1
2hyperandrogenism31.7SHBG, IGFBP1, CYP17A1, CYP11A1, RETN, INS
3infertility31.3LSL, GNRH1, BMP15, SHBG, IGFBP1, CYP11A1
4anovulation31.1IGFBP1, INS, LEP, SULT2A1, SHBG, GHRL
5glucose intolerance31.0CAPN10, LSL, RBP4, GHRL, SHBG, IGFBP1
6diabetes mellitus31.0CAPN10, LSL, RBP4, GHRL, SHBG, IGFBP1
7hyperinsulinism30.9LSL, GNRH1, GHRL, SHBG, IGFBP1, RETN
8hypertension30.9CYP17A1, RETN, INS, LEP
9acanthosis nigricans30.9SHBG, INS, LEP, ADIPOQ
10gestational diabetes30.9LSL, RBP4, SHBG, IGFBP1, RETN, NAMPT
11ovarian hyperstimulation syndrome30.8GNRH1
12premature ovarian failure30.8GNRH1, BMP15, SHBG, CYP11A1, GDF9
13amenorrhea30.8AMH, GNRH1, BMP15, SHBG, INS, LEP
14type 2 diabetes mellitus30.7CAPN10, LSL, RBP4, GHRL, SHBG, IGFBP1
15atherosclerosis30.7CAPN10, LSL, RBP4, GHRL, SHBG, RETN
16hyperprolactinemia30.6SHBG, GNRH1
17hepatitis30.6IGFBP1
18acne30.6SHBG
19fatty liver disease30.5RBP4, CYP17A1, RETN, INS, LEP, ADIPOQ
20down syndrome30.5FST
21hyperglycemia30.4LSL, GHRL, IGFBP1, RETN, NAMPT, INS
22cushing's syndrome30.4INS, SULT2A1
23coronary artery disease30.4GHRL, IGFBP1, RETN, NAMPT, INS, ADIPOQ
24congenital adrenal hyperplasia30.4CYP11A1, CYP17A1, GNRH1, LSL
25vascular disease30.4ADIPOQ, INS, NAMPT, RETN
26ovarian disease30.4GNRH1, SHBG, IGFBP1
27pancreatitis30.4INS
28graves' disease30.3SHBG
29hypogonadism30.3GNRH1, GHRL, SHBG, INS, LEP, ADIPOQ
30pituitary adenoma30.3GNRH1, GHRL, LEP, FST
31adrenal adenoma30.2CYP17A1, CYP11A1, SULT2A1
32acromegaly30.1ADIPOQ, LSL, GNRH1, GHRL, SHBG, IGFBP1
33adenoma30.1GNRH1, GHRL, SHBG, IGFBP1, CYP17A1, CYP11A1
34pre-eclampsia30.1LSL, SHBG, IGFBP1, RETN, LEP, FST
35morbid obesity30.1LSL, GHRL, RETN, INS, LEP, ADIPOQ
36hypothyroidism30.1LSL, GHRL, SHBG, RETN, LEP, ADIPOQ
37lipodystrophy30.1ADIPOQ, LEP, INS, RETN, LSL
38metabolic syndrome x30.1LSL, IGFBP1, INS, LEP, ADIPOQ
39eating disorder30.1LSL, GHRL, RETN, LEP
40proteinuria30.1LSL, RBP4, INS, ADIPOQ
41adenocarcinoma30.1IGFBP1, GHRL
42prolactinoma30.1GNRH1
43anorexia nervosa30.1LSL, GHRL, SHBG, IGFBP1, RETN, LEP
44ovarian cancer30.1GNRH1, RBP4, CYP17A1, FST
45klinefelter's syndrome30.1SHBG, GNRH1
46endometrial carcinoma30.1GNRH1, IGFBP1, CYP17A1, FST
47congenital generalized lipodystrophy type 230.0LSL, INS, LEP, ADIPOQ
48turner syndrome30.0IGFBP1, SHBG, BMP15
49diabetic retinopathy30.0IGFBP1, INS
50hypogonadotropism30.0GNRH1

Graphical network of the top 20 diseases related to Polycystic Ovary Syndrome:



Diseases related to polycystic ovary syndrome

Clinical Features for Polycystic Ovary Syndrome

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46OMIM
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Clinical features from OMIM:

184700

Drugs & Therapeutics for Polycystic Ovary Syndrome

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Polycystic Ovary Syndrome

Drug clinical trials:

Search ClinicalTrials for Polycystic Ovary Syndrome

Search NIH Clinical Center for Polycystic Ovary Syndrome

Search CenterWatch for Polycystic Ovary Syndrome

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Polycystic Ovary Syndrome

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Anatomical Context for Polycystic Ovary Syndrome

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32MalaCards
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MalaCards organs/tissues related to Polycystic Ovary Syndrome:

32
Ovary, Heart, Skin, Adrenal gland, Endothelial, Adipocyte, Testes, Pituitary, Thyroid, Skeletal muscle, Bone, Liver, Monocytes, Brain, Prostate, Breast, Tongue, Adrenal cortex, Kidney, Whole blood, Placenta, Cortex, Pancreas, Eye

Animal Models for Polycystic Ovary Syndrome or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Polycystic Ovary Syndrome:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000537611.9CYP17A1, GHRL, RBP4, GNRH1, CAPN10, AMH
2MP:000537911.3FST, AMH, CAPN10, BMP15, RBP4, CYP11A1
3MP:000538911.0AMH, GNRH1, BMP15, RBP4, CYP11A1, GDF9
4MP:000537010.9CAPN10, GNRH1, IGFBP1, RETN, INS, LEP
5MP:000537510.7RETN, CAPN10

Publications for Polycystic Ovary Syndrome

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50PubMed
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Articles related to Polycystic Ovary Syndrome:

(show top 50)    (show all 1963)
idTitleAuthorsYear
1
Plasminogen Activator Inhibitor-1 -675 4G/5G Polymorphism and Polycystic Ovary Syndrome Risk: A Meta Analysis. (24435452)
2014
2
Cardiovascular disease in polycystic ovary syndrome. (23362921)
2013
3
Metformin inhibits follicle-stimulating hormone (FSH) action in human granulosa cells: relevance to polycystic ovary syndrome. (23846817)
2013
4
Adverse effects of the common treatments for polycystic ovary syndrome: a systematic review and meta-analysis. (24092830)
2013
5
Subclinical hypothyroidism in young women with polycystic ovary syndrome: an analysis of clinical, hormonal, and metabolic parameters. (23103018)
2013
6
The contribution of diet, physical activity and sedentary behaviour to body mass index in women with and without polycystic ovary syndrome. (23771201)
2013
7
Polycystic ovary syndrome and nonalcoholic fatty liver in obese adolescents: association with metabolic risk profile. (24034940)
2013
8
Differences in the skin-surface laser-Doppler signals between polycystic-ovary-syndrome and normal subjects. (24118419)
2013
9
The use of berberine for women with polycystic ovary syndrome undergoing IVF treatment. (23869585)
2013
10
Relationship of QT dispersion with sex hormones and insulin in young women with polycystic ovary syndrome: an observational study. (24172835)
2013
11
Interventions for the metabolic dysfunction in polycystic ovary syndrome. (23624033)
2013
12
Polycystic ovary syndrome: a review of treatment options with a focus on pharmacological approaches. (23946629)
2013
13
Increased mean glucose levels in patients with polycystic ovary syndrome and hyperandrogenemia as determined by continuous glucose monitoring. (23072215)
2013
14
Increased epicardial fat thickness is related with body mass index in women with polycystic ovary syndrome. (23884834)
2013
15
Metformin decreases serum 8-hydroxy-2'-deoxyguanosine levels in polycystic ovary syndrome. (23122829)
2013
16
SNP rs2470152 in CYP19 is correlated to aromatase activity in Chinese polycystic ovary syndrome patients. (21972004)
2012
17
Polymorphisms of FEM1A gene in patients with polycystic ovary syndrome]. (22678803)
2012
18
Serum visfatin is elevated in Chinese women with polycystic ovary syndrome, but might not be a reliable predictor of their glucose intolerance. (22824749)
2012
19
Association of genetic variants in the two isoforms of 5I+-reductase, SRD5A1 and SRD5A2, in lean patients with polycystic ovary syndrome. (21530059)
2011
20
Role of decreased circulating hepcidin concentrations in the iron excess of women with the polycystic ovary syndrome. (21209031)
2011
21
Sex hormone-binding globulin concentrations before conception as a predictor for gestational diabetes in women with polycystic ovary syndrome. (20943702)
2010
22
Adiponectin and resistin concentrations after glucose load in adolescents with polycystic ovary syndrome. (19639497)
2010
23
Flexible GnRH antagonist protocol versus GnRH agonist long protocol in patients with polycystic ovary syndrome treated for IVF: a prospective randomised controlled trial (RCT). (20008886)
2010
24
Genetic variations of solute carrier family 30 (zinc transporter) member 8 (SLC30A8) are not associated with polycystic ovary syndrome. (19108828)
2009
25
The expression of resistin in adipose tissues of patients with polycystic ovary syndrome and insulin resistance. (19821101)
2009
26
Central-to-peripheral fat ratio, but not peripheral body fat, is related to insulin resistance and androgen markers in polycystic ovary syndrome. (19905998)
2009
27
Adiponectin levels reflect the different phenotypes of polycystic ovary syndrome: study in normal weight, normoinsulinemic patients. (19700156)
2009
28
Regulation of catechol O-methyltransferase expression in granulosa cells: a potential role for follicular arrest in polycystic ovary syndrome. (17612537)
2008
29
Increased serum advanced glycation end-products is a distinct finding in lean women with polycystic ovary syndrome (PCOS). (18363886)
2008
30
Disparate genetic influences on polycystic ovary syndrome (PCOS) and type 2 diabetes revealed by a lack of association between common variants within the TCF7L2 gene and PCOS. (17805508)
2007
31
Serum anti-mullerian hormone concentrations are not altered by acute administration of follicle stimulating hormone in polycystic ovary syndrome and normal women. (17299061)
2007
32
Calpain-10 variants and haplotypes are associated with polycystic ovary syndrome in Caucasians. (17106059)
2007
33
Investigation of hypothalamo-pituitary-gonadal axis and glucose intolerance among the first-degree female relatives of women with polycystic ovary syndrome. (17336975)
2007
34
Relation of nutrients and hormones in polycystic ovary syndrome. (17344488)
2007
35
Mutation analysis of the WNT-4 gene in patients with polycystic ovary syndrome. (17071531)
2006
36
Use of yasmin in the treatment of women with polycystic ovary syndrome]. (16889184)
2006
37
Mutations in the hereditary hemochromatosis gene are not associated with the increased body iron stores observed in overweight and obese women with polycystic ovary syndrome. (17065702)
2006
38
A randomized controlled trial of the efficacy of rosiglitazone and clomiphene citrate versus metformin and clomiphene citrate in women with clomiphene citrate-resistant polycystic ovary syndrome. (16595222)
2006
39
The CC genotype of the GNAS T393C polymorphism is associated with obesity and insulin resistance in women with polycystic ovary syndrome. (17062894)
2006
40
Genetic determinants of insulin action in polycystic ovary syndrome. (15926113)
2005
41
Prevalence of CYP21 mutations and IRS1 variant among women with polycystic ovary syndrome and adrenal androgen excess. (15705377)
2005
42
Leptin and its association with polycystic ovary syndrome: a twin study. (15497495)
2004
43
Genetic and environmental aspect of polycystic ovary syndrome. (15008257)
2003
44
Polycystic ovary syndrome: the new millenium. (11694344)
2001
45
Effect of long-term treatment with metformin added to hypocaloric diet on body composition, fat distribution, and androgen and insulin levels in abdominally obese women with and without the polycystic ovary syndrome. (10946879)
2000
46
Impact of insulin and body mass index on metabolic and endocrine variables in polycystic ovary syndrome. (10024076)
1999
47
Serum total renin levels after ovarian electrocautery in women with polycystic ovary syndrome. (9859025)
1998
48
Early polycystic ovary-like syndrome in girls with central precocious puberty and exaggerated adrenal response. (7581961)
1995
49
The relation between clinical manifestations of polycystic ovary syndrome and beta-cell function. (8458101)
1993
50
Glycosaminoglycan deposition in the acanthosis nigricans lesions of the polycystic ovary syndrome. (6344826)
1983

Genetic Variations for Polycystic Ovary Syndrome

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Expression for genes affiliated with Polycystic Ovary Syndrome

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Polycystic Ovary Syndrome

Search GEO for disease gene expression data for Polycystic Ovary Syndrome.

Pathways for genes affiliated with Polycystic Ovary Syndrome

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Sources:
29KEGG, 37NCBI BioSystems Database, 52R&D Systems, 12EMD Millipore, 53Reactome
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Compounds for genes affiliated with Polycystic Ovary Syndrome

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44Novoseek, 59Tocris Bioscience, 11DrugBank, 24HMDB, 28IUPHAR, 49PharmGKB, 2BitterDB
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Compounds related to Polycystic Ovary Syndrome according to GeneCards/GeneDecks:

(show top 50)    (show all 150)
idCompoundScoreTop Affiliating Genes
1testosterone44 59 11 2415.4GHRL, ADIPOQ, SULT2A1, SHBG, IGFBP1, CYP17A1
2cholesterol44 28 11 2415.3SULT2A1, LEP, INS, NAMPT, RETN, CYP11A1
3lipid4412.3GHRL, SHBG, RETN, IGFBP1, CYP17A1, NAMPT
4progesterone44 59 28 11 2416.2AMH, FST, SULT2A1, LEP, RETN, BMP15
5creatinine4412.1LSL, GNRH1, RBP4, GHRL, NAMPT, SHBG
6metformin44 49 1114.1CYP17A1, SHBG, GHRL, CYP11A1, RETN, NAMPT
7dexamethasone44 49 28 1115.1FST, INS, NAMPT, RETN, CYP11A1, CYP17A1
8dhea4412.0CYP11A1, ADIPOQ, SULT2A1, LEP, INS, RETN
9rosiglitazone44 49 28 11 2416.0CYP17A1, RETN, NAMPT, INS, LEP, ADIPOQ
10androstenedione44 2413.0LSL, GNRH1, RBP4, SHBG, IGFBP1, CYP17A1
11steroid4411.9SHBG, IGFBP1, RBP4, GNRH1, CYP17A1, LEP
12thyroxine44 2412.9LSL, GNRH1, ADIPOQ, LEP, INS, RETN
13pioglitazone44 49 28 1114.9SHBG, IGFBP1, CYP17A1, RETN, NAMPT, INS
14acth4411.8SULT2A1, FST, LEP, CYP11A1, IGFBP1, GHRL
15arginine4411.8CYP17A1, ADIPOQ, LEP, INS, SHBG, GHRL
16ribonucleic acid4411.8FST, CYP17A1, NAMPT, GDF9, GNRH1, RBP4
17fatty acid4411.7GHRL, IGFBP1, RETN, INS, ADIPOQ, NAMPT
18lactate4411.7FST, IGFBP1, GNRH1, GHRL, LSL, SHBG
19c-peptide4411.7SHBG, GHRL, IGFBP1, RETN, LEP, ADIPOQ
20estrone44 28 11 2414.7ADIPOQ, IGFBP1, CYP17A1, LSL, GNRH1, SHBG
21dihydrotestosterone44 28 11 2414.7IGFBP1, SHBG, GNRH1, CYP17A1, CYP11A1, LEP
22estradiol44 11 2413.6AMH, GNRH1, SHBG, CYP17A1, CYP11A1, FST
23dehydroepiandrosterone sulfate4411.6GNRH1, RBP4, SHBG, IGFBP1, CYP11A1, SULT2A1
24gnrh4411.6GNRH1, GHRL, CYP11A1, CYP17A1, IGFBP1, SHBG
25tamoxifen44 49 28 1114.6LSL, GNRH1, SHBG, IGFBP1, SULT2A1, AMH
2617-hydroxyprogesterone44 2412.6GNRH1, ADIPOQ, RETN, CYP11A1, CYP17A1, IGFBP1
27triiodothyronine4411.6GHRL, SULT2A1, LEP, IGFBP1, SHBG, RBP4
28carbohydrates4411.5ADIPOQ, LEP, INS, IGFBP1, GHRL, LSL
29vitamin a44 11 2413.4CYP17A1, FST, ADIPOQ, RETN, LEP, IGFBP1
30octreotide44 59 28 1114.4LSL, GNRH1, IGFBP1, INS, ADIPOQ, GHRL
31triacylglycerol4411.4LSL, LEP, RBP4, GHRL, INS, ADIPOQ
32epinephrine44 11 2413.4INS, LEP, SHBG, LSL, GNRH1, GHRL
33progestin4411.4CYP11A1, GNRH1, SHBG, IGFBP1, ADIPOQ, CYP17A1
34glucose4411.3NAMPT, LSL, GHRL, FST, RBP4
35acipimox44 2812.3GHRL, INS, LSL, LEP, ADIPOQ
36nash4411.3INS, LEP, RETN, LSL, ADIPOQ
37corticosterone44 59 2413.3IGFBP1, GHRL, CYP11A1, LEP, LSL, CYP17A1
38orlistat44 59 1113.3LEP, ADIPOQ, LSL, INS, GHRL
39p0024411.3RBP4, LSL, IGFBP1, RETN, LEP, ADIPOQ
40thiazolidinedione4411.3LEP, RETN, INS, CYP17A1, ADIPOQ
41hydrocortisone44 2 59 1114.2ADIPOQ, LSL, INS, GHRL, IGFBP1, SHBG
4211beta-hydroxysteroid4411.2RETN, ADIPOQ, LEP, CYP11A1, CYP17A1
43alanine4411.2LSL, RBP4, ADIPOQ, SHBG, RETN, INS
44nifedipine44 49 28 1114.1CYP17A1, GHRL, GNRH1, ADIPOQ, LEP, CYP11A1
45valproate4411.1SHBG, IGFBP1, LSL, CYP17A1, CYP11A1
46norepinephrine44 11 2413.1RETN, GNRH1
47sibutramine44 1112.0INS, LEP, LSL, ADIPOQ
48beta-hydroxybutyrate4410.9INS, LEP, IGFBP1, LSL
49olanzapine49 44 28 11 2414.9LEP, ADIPOQ, INS, GHRL, LSL
50fibrinogen4410.9RETN, ADIPOQ, LEP, IGFBP1, INS, NAMPT

GO Terms for genes affiliated with Polycystic Ovary Syndrome

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16Gene Ontology
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Cellular components related to Polycystic Ovary Syndrome according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00561511.5ADIPOQ, AMH, GNRH1, BMP15, RBP4, GHRL
2extracellular regionGO:00557611.3GHRL, RBP4, GNRH1, AMH, SHBG, IGFBP1
3secretory granule lumenGO:03477410.7INS, GHRL

Biological processes related to Polycystic Ovary Syndrome according to GeneCards/GeneDecks:

(show all 23)
idNameGO IDScoreTop Affiliating Genes
1glucose metabolic processGO:00600611.2ADIPOQ, LEP, INS, GHRL
2positive regulation of glucose importGO:04632611.1ADIPOQ, INS, CAPN10
3positive regulation of insulin secretionGO:03202411.1CAPN10, RBP4, GHRL
4cell-cell signalingGO:00726711.1AMH, GNRH1, NAMPT, INS
5response to insulin stimulusGO:03286811.1LEP, RETN, RBP4
6steroid metabolic processGO:00820211.0SULT2A1, CYP11A1, CYP17A1
7response to fungicideGO:06099211.0CYP17A1, CYP11A1
8dibenzo-p-dioxin metabolic processGO:01889411.0CYP17A1, CYP11A1
9biphenyl metabolic processGO:01887911.0CYP17A1, CYP11A1
10response to insecticideGO:01708511.0CYP17A1, CYP11A1
11phthalate metabolic processGO:01896311.0CYP17A1, CYP11A1
12phenol-containing compound metabolic processGO:01895811.0CYP17A1, CYP11A1
13response to ethanolGO:04547111.0ADIPOQ, RBP4, GNRH1
14positive regulation of insulin receptor signaling pathwayGO:04662810.9INS, LEP
15glucose homeostasisGO:04259310.9RBP4, INS, ADIPOQ
16negative regulation of gluconeogenesisGO:04572110.9ADIPOQ, INS
17cellular response to antibioticGO:07123610.9CYP11A1, CYP17A1
18adult feeding behaviorGO:00834310.8LEP, GHRL
19response to vitamin EGO:03319710.7LEP, CYP11A1
20Leydig cell differentiationGO:03332710.7CYP17A1, CYP11A1
21sterol metabolic processGO:01612510.7CYP11A1, CYP17A1
22positive regulation of cellular protein metabolic processGO:03227010.6INS, ADIPOQ
23sex differentiationGO:00754810.4CYP17A1, AMH

Molecular functions related to Polycystic Ovary Syndrome according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:00517911.0ADIPOQ, LEP, INS, RETN, GNRH1, AMH
2cytokine activityGO:00512510.9ADIPOQ, NAMPT, GDF9, BMP15
3growth factor activityGO:00808310.6AMH, BMP15, GDF9, LEP

Products for genes affiliated with Polycystic Ovary Syndrome

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Sources for Polycystic Ovary Syndrome

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
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39NCIt
40NDF-RT
43NINDS
44Novoseek
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47OMIM via Orphanet
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