MCID: PLY062
MIFTS: 11

Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy malady

Summaries for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

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46OMIM, 32MalaCards
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MalaCards: Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy is related to polyhydramnios and peutz-jeghers syndrome. An important gene associated with Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy is STRADA (STE20-related kinase adaptor alpha), and among its related pathways are Integrated Pancreatic Cancer Pathway and Translation Insulin regulation of translation.

Description from OMIM:46 611087

Aliases & Classifications for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

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Aliases & Descriptions:

polyhydramnios, megalencephaly, and symptomatic epilepsy 46


Related Diseases for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

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17GeneCards, 18GeneDecks
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Diseases related to Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1polyhydramnios30.5STRADA
2peutz-jeghers syndrome10.0STRADA, STK11

Clinical Features for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

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46OMIM
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Clinical features from OMIM:

611087

Drugs & Therapeutics for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

Drug clinical trials:

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Search NIH Clinical Center for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

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Genetic Tests for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

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Anatomical Context for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

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Animal Models for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy or affiliated genes

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Publications for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

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Genetic Variations for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

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Expression for genes affiliated with Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

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Pathways for genes affiliated with Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

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37NCBI BioSystems Database, 29KEGG, 53Reactome
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Compounds for genes affiliated with Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

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GO Terms for genes affiliated with Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

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16Gene Ontology
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Biological processes related to Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1activation of protein kinase activityGO:0321479.1STRADA, STK11
2protein phosphorylationGO:0064689.1STRADA, STK11
3cell cycle arrestGO:0070509.0STRADA, STK11
4insulin receptor signaling pathwayGO:0082868.8STRADA, STK11

Molecular functions related to Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein serine/threonine kinase activityGO:0046749.1STRADA, STK11
2protein kinase activator activityGO:0302958.8STRADA, STK11

Products for genes affiliated with Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

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Sources for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet