MCID: PLY062
MIFTS: 11

Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy malady

Summaries for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

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47OMIM, 33MalaCards
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MalaCards: Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy is related to polyhydramnios and megalencephaly. An important gene associated with Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy is STRADA (STE20-related kinase adaptor alpha), and among its related pathways are Integrated Pancreatic Cancer Pathway and Translation Insulin regulation of translation.

Description from OMIM:47 611087

Aliases & Classifications for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

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47OMIM
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Aliases & Descriptions:

polyhydramnios, megalencephaly, and symptomatic epilepsy 47


Related Diseases for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

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17GeneCards, 18GeneDecks
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Diseases related to Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1polyhydramnios30.6STRADA
2megalencephaly10.4
3peutz-jeghers syndrome10.0STRADA, STK11

Clinical Features for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

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47OMIM
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Clinical features from OMIM:

611087

Drugs & Therapeutics for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

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5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

Drug clinical trials:

Search ClinicalTrials for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

Search NIH Clinical Center for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

Search CenterWatch for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

Genetic Tests for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

Anatomical Context for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

Animal Models for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy or affiliated genes

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28inGenious Targeting Laboratory
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Publications for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

Genetic Variations for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

Expression for genes affiliated with Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

Search GEO for disease gene expression data for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy.

Pathways for genes affiliated with Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

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38NCBI BioSystems Database, 30KEGG, 54Reactome
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Compounds for genes affiliated with Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

GO Terms for genes affiliated with Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

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16Gene Ontology
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Biological processes related to Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1activation of protein kinase activityGO:0321479.1STRADA, STK11
2protein phosphorylationGO:0064689.1STRADA, STK11
3cell cycle arrestGO:0070509.0STRADA, STK11
4insulin receptor signaling pathwayGO:0082868.8STRADA, STK11

Molecular functions related to Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein serine/threonine kinase activityGO:0046749.1STRADA, STK11
2protein kinase activator activityGO:0302958.8STRADA, STK11

Products for genes affiliated with Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Polyhydramnios, Megalencephaly, and Symptomatic Epilepsy

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet