MCID: PLY020
MIFTS: 46

Polyradiculoneuropathy malady

Summaries for Polyradiculoneuropathy

About this section


Wikipedia:63 Polyradiculoneuropathy describes a condition in which polyneuropathy and polyradiculopathy occur... more...

MalaCards based summary: Polyradiculoneuropathy is related to chronic inflammatory demyelinating polyradiculoneuropathy and neuropathy. An important gene associated with Polyradiculoneuropathy is PMP22 (peripheral myelin protein 22), and among its related pathways are Interferon Pathway and Immune response Bacterial infections in normal airways. The compounds gamma globulin and mdms have been mentioned in the context of this disorder. Affiliated tissues include t cells, brain and spinal cord, and related mouse phenotypes are muscle and digestive/alimentary.

Aliases & Classifications for Polyradiculoneuropathy

About this section
Sources:
9Disease Ontology, 43Novoseek, 60UMLS, 33MeSH, 55SNOMED-CT
See all sources

Polyradiculoneuropathy, Aliases & Descriptions:

Name: Polyradiculoneuropathy 9 43 60


External Ids:

Disease Ontology9 DOID:4308
SNOMED-CT55 128078004
MeSH33 D011129

Related Diseases for Polyradiculoneuropathy

About this section

Diseases related to Polyradiculoneuropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 174)
idRelated DiseaseScoreTop Affiliating Genes
1chronic inflammatory demyelinating polyradiculoneuropathy32.1PMP22, MPZ, CCR5, IFNB1
2neuropathy30.8PMP22, MPZ, ALB, MBP
3hereditary neuropathies30.5PMP22, MPZ
4hepatitis30.5CXCL12, STAT1, IFNB1, CD40LG
5glomerulonephritis30.4CCR5, ALB, CD40LG
6polyneuropathy30.4PMP22, MPZ, MBP, CD40LG
7viral hepatitis30.3HLA-DRB1, STAT1, IFNB1
8optic neuritis30.3MPZ, IFNB1, MBP
9neuritis30.1PMP2, PMP22, MPZ, MBP
10myasthenia gravis30.1CCR5, IFNG, IL2, MBP
11hepatitis b30.1HLA-DRB1, CCR5, IFNG, ALB
12systemic lupus erythematosus30.0HLA-DRB1, STAT1, CCR5, IFNB1, IFNG, IL2
13eosinophilia30.0STAT1, IFNG, IL2
14malaria30.0HLA-DRB1, IFNG, ALB
15inflammatory bowel disease29.9STAT3, STAT1, CCR5, IFNG
16influenza29.9STAT1, CCR5, CCL19, IFNB1, IFNG
17guillain-barre syndrome29.9PMP2, PMP22, MPZ, CCR5, MBP, CD40LG
18connective tissue disease29.8HLA-DRB1, IL2, ALB, CD40LG
19psoriasis29.7IL2, IFNG, STAT3, HLA-DRB1
20hepatocellular carcinoma29.4HLA-DRB1, CXCL12, STAT3, CCL19, CCL21, IFNB1
21leukemia29.2HLA-DRB1, CXCL12, STAT3, STAT1, IFNB1, IFNG
22neuropathy, recurrent, with pressure palsies10.6PMP22
23periapical granuloma10.5CCR5
24charcot-marie-tooth disease, type 1a10.5PMP22, MPZ
25motor peripheral neuropathy10.5PMP22, MPZ
26acute disseminated encephalomyelitis10.5MBP
27roussy-levy syndrome10.5PMP22, MPZ
28neuropathy, congenital hypomyelinating10.5PMP22, MPZ
29aplastic anemia10.5IFNG
30tooth disease10.5MPZ, PMP22
31brachial plexus neuropathy10.5MPZ, PMP22
32primary immunodeficiency disease10.5CD40LG
33dejerine-sottas disease10.5PMP22, MPZ
34syphilis10.5CCR5
35hemorrhagic fever10.5CD40LG
36charcot-marie-tooth neuropathy type 110.5PMP22, MPZ
37myelitis10.4MBP
38pelizaeus-merzbacher disease10.4MBP, MPZ
39capillary leak syndrome10.4IL2
40diabetic neuropathy10.4PMP22, MPZ
41lupus erythematosus10.4
42primary progressive multiple sclerosis10.4IFNB1, MBP
43secondary progressive multiple sclerosis10.3IFNB1, MBP
44encephalitis10.3MBP, CCR5
45neuromyelitis optica10.3IFNB1, MBP
46leprosy10.3HLA-DRB1, IL2
47hyper-ige recurrent infection syndrome10.3IFNG, STAT3
48charcot-marie-tooth disease10.3PMP22, MPZ, MBP
49neurilemmoma10.3PMP22, MPZ, MBP
50dengue disease10.3IFNB1, CD40LG

Graphical network of the top 20 diseases related to Polyradiculoneuropathy:



Diseases related to polyradiculoneuropathy

Symptoms for Polyradiculoneuropathy

About this section

Drugs & Therapeutics for Polyradiculoneuropathy

About this section

Drug clinical trials:

Search ClinicalTrials for Polyradiculoneuropathy

Search NIH Clinical Center for Polyradiculoneuropathy

Genetic Tests for Polyradiculoneuropathy

About this section

Anatomical Context for Polyradiculoneuropathy

About this section

MalaCards organs/tissues related to Polyradiculoneuropathy:

31
T cells, Brain, Spinal cord, Thyroid, Tongue, Kidney, Bone, Thymus, Heart, Liver, Lung, Skin, B cells, Pituitary

Animal Models for Polyradiculoneuropathy or affiliated genes

About this section

Publications for Polyradiculoneuropathy

About this section

Articles related to Polyradiculoneuropathy:

(show top 50)    (show all 449)
idTitleAuthorsYear
1
Long-term Immunoglobulin therapy for chronic inflammatory demyelinating polyradiculoneuropathy. (25556954)
2015
2
Triple-stimulation technique improves the diagnosis of chronic inflammatory demyelinating polyradiculoneuropathy. (25571892)
2015
3
Progressive bilateral ptosis in a patient with midbrain metastasis and chronic inflammatory demyelinating polyradiculoneuropathy. (24594646)
2014
4
SjAPgren's syndrome associated chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) treated with autologous and subsequently allogeneic haematopoietic SCT (HSCT). (23503533)
2013
5
Chronic inflammatory demyelinating polyradiculoneuropathy in a patient with Crohn's disease. (23291687)
2013
6
Chronic inflammatory demyelinating polyradiculoneuropathy in a patient with systemic lupus erythematosus and good outcome with rituximab treatment. (21922339)
2012
7
CD8+ T-cell immunity in chronic inflammatory demyelinating polyradiculoneuropathy. (22238416)
2012
8
Chronic inflammatory demyelynating polyradiculoneuropathy in childhood and response to IVIg. (24391437)
2011
9
Brachial and lumbar plexuses in chronic inflammatory demyelinating polyradiculoneuropathy: MRI assessment including apparent diffusion coefficient. (20405114)
2011
10
Pulsed high-dose dexamethasone versus standard prednisolone treatment for chronic inflammatory demyelinating polyradiculoneuropathy (PREDICT study): a double-blind, randomised, controlled trial. (20133204)
2010
11
Understanding the consequences of chronic inflammatory demyelinating polyradiculoneuropathy from impairments to activity and participation restrictions and reduced quality of life: the ICE study. (21040143)
2010
12
A case of acute polyradiculoneuropathy, drug-induced hypersensitivity, and HHV-6 infection. (19273829)
2009
13
Acute polyradiculoneuropathy following wasp sting. (19934578)
2009
14
Chronic inflammatory demyelinating polyradiculoneuropathy: a role for haematopoietic stem cell transplantation? (18958756)
2008
15
Rituximab therapy in chronic inflammatory demyelinating polyradiculoneuropathy with anti-SGPG IgM antibody. (16814550)
2006
16
European Federation of Neurological Societies/Peripheral Nerve Society guideline on management of chronic inflammatory demyelinating polyradiculoneuropathy: report of a joint task force of the European Federation of Neurological Societies and the Peripheral Nerve Society. (16643309)
2006
17
Chronic inflammatory demyelinating polyradiculoneuropathy: new views and guidelines. (16221282)
2005
18
Antibodies to peripheral nerve myelin proteins in chronic inflammatory demyelinating polyradiculoneuropathy. (15958128)
2005
19
T cell reactivity to P0, P2, PMP-22, and myelin basic protein in patients with Guillain-Barre syndrome and chronic inflammatory demyelinating polyradiculoneuropathy. (16170091)
2005
20
Chronic inflammatory demyelinating polyradiculoneuropathy in patients with liver transplantation. (15372442)
2004
21
Diffuse spinal and intercostal nerve involvement in chronic inflammatory demyelinating polyradiculoneuropathy: MRI findings. (16440223)
2003
22
Chronic inflammatory demyelinating polyradiculoneuropathy in diabetic patients. (12661048)
2003
23
Waldenstrom's Macroglobulinaemia Presenting as Demyelinating Polyradiculoneuropathy. (24326654)
2002
24
Proposed revised electrophysiological criteria for chronic inflammatory demyelinating polyradiculoneuropathy. (11754181)
2002
25
Corticosteroids for chronic inflammatory demyelinating polyradiculoneuropathy. (11869620)
2002
26
Randomized controlled trial of IVIg in untreated chronic inflammatory demyelinating polyradiculoneuropathy. (11222785)
2001
27
Inflammatory polyradiculoneuropathy with spinal cord involvement and lethal [correction of letal] outcome after hepatitis B vaccination. (11412876)
2001
28
Chronic inflammatory demyelinating polyradiculoneuropathy with histologically proven optic neuritis. (11484826)
2001
29
Ataxic form of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). (10809947)
2000
30
Chronic inflammatory demyelinating polyradiculoneuropathy and severe peripheral oedema: a renal explanation. (10844803)
2000
31
Chronic inflammatory demyelinating polyradiculoneuropathy: a prevalence study in south east England. (10209187)
1999
32
Acute inflammatory demyelinating polyradiculoneuropathy associated with hyperIgEemia and atopic dermatitis. (9562273)
1998
33
Anti-GQ1b and anti-GT1a IgG antibodies in a patient with acute demyelinating polyradiculoneuropathy without ophthalmoplegia. (9328270)
1997
34
A novel trial design to study the effect of intravenous immunoglobulin in chronic inflammatory demyelinating polyradiculoneuropathy. (8936360)
1996
35
Acute inflammatory demyelinating polyradiculoneuropathy following antirabies vaccine. (9251443)
1996
36
Long-term treatment of chronic inflammatory demyelinating polyradiculoneuropathy with plasma exchange or intravenous immunoglobulin. (7633875)
1995
37
Glomerulonephritis associated with inflammatory demyelinating polyradiculoneuropathy: a case report and review of the literature. (8502319)
1993
38
Nerve root enhancement with MRI in inflammatory demyelinating polyradiculoneuropathy. (8451012)
1993
39
Prognosis in long-term immunosuppressive treatment of refractory chronic inflammatory demyelinating polyradiculoneuropathy. (1738011)
1992
40
Chronic inflammatory demyelinating polyradiculoneuropathy associated with Evans' syndrome. (1341469)
1992
41
Chronic inflammatory demyelinating polyradiculoneuropathy: comparison of patients with and without an associated monoclonal gammopathy. (1603342)
1992
42
Acquired factor VIII deficiency and polyradiculoneuropathy. (1901137)
1991
43
Evoked potentials suggest cranial nerves and CNS involvement in chronic relapsing polyradiculoneuropathy. (2731562)
1989
44
Polyradiculoneuropathy in transfusion-associated AIDS and dorsal root pathology. (2928972)
1989
45
Class and IgG subclass distribution of antibodies against peripheral nerve myelin in sera from patients with inflammatory demyelinating polyradiculoneuropathy. (2464267)
1988
46
Absence of antimyelin antibodies and serum demyelinating factors in most patients with chronic inflammatory demyelinating polyradiculoneuropathy. (3267485)
1988
47
Fulminant leukemic polyradiculoneuropathy in a case of B-cell prolymphocytic leukemia. A clinicopathologic report. (3040217)
1987
48
Idiopathic inflammatory polyradiculoneuropathy: evaluation of clinical and laboratory data and therapeutic considerations. (6862843)
1983
49
British multicentre trial of plasma exchange in acute inflammatory polyradiculoneuropathy (AIP). (6757939)
1982
50
Polyradiculoneuropathy in Addison's disease. Case report and review of literature. (558557)
1977

Variations for Polyradiculoneuropathy

About this section

Expression for genes affiliated with Polyradiculoneuropathy

About this section
Search GEO for disease gene expression data for Polyradiculoneuropathy.

Pathways for genes affiliated with Polyradiculoneuropathy

About this section

Pathways related to Polyradiculoneuropathy according to GeneCards Suite gene sharing:

(show top 50)    (show all 58)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.7STAT1, IFNB1, IFNG
2
Show member pathways
Transcription NF kB signaling pathway58
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response58
9.7IFNG, IFNB1, STAT1
39.7STAT1, IFNB1, IFNG
49.6IFNG, STAT1, STAT3
5
Show member pathways
Development Thrombopoetin signaling via JAK STAT pathway58
9.6IFNG, STAT1, STAT3
6
Show member pathways
9.6IFNG, STAT1, STAT3
7
Show member pathways
IFN-gamma pathway36
9.6STAT3, STAT1, IFNG
89.6HLA-DRB1, CXCL12, IFNG
9
Show member pathways
9.5STAT3, STAT1, IL2
109.5IL2, IFNG, IFNB1
119.5IFNG, IL2, CD40LG
129.5STAT1, STAT3, SH2D2A
139.5IFNG, STAT3, PRF1
149.4HLA-DRB1, STAT1, IFNB1, IFNG
159.4STAT1, STAT3, CXCL12, HLA-DRB1
16
Show member pathways
Ras signaling in the CD4+ TCR pathway36
9.4IL2, IFNG, PRF1
17
Show member pathways
9.4STAT3, STAT1, CCR5, IFNG
189.3STAT1, IFNG, IL2, TBX21
19
Show member pathways
Calcium signaling in the CD4+ TCR pathway36
9.3IFNG, IL2, TBX21, CD40LG
20
Show member pathways
9.3CXCL12, STAT3, STAT1, IL2
219.3PMP22, MPZ, MBP
22
Show member pathways
Immune response IL 22 signaling pathway58
G protein signaling N RAS regulation pathway58
9.3HLA-DRB1, STAT3, STAT1, IL2
239.3HLA-DRB1, IFNB1, IFNG, IL2
24
Show member pathways
BCR signaling pathway36
TCR Signaling Pathway36
9.2CD40LG, IL2, IFNG, CCR5
25
Show member pathways
IL23-mediated signaling events36
Immune response IL 10 signaling pathway58
Angiopoietin receptor Tie2-mediated signaling36
Development PDGF signaling via STATs and NF kB58
Development Angiopoietin Tie2 signaling58
9.2IL2, IFNG, STAT1, STAT3
26
Show member pathways
IL-2 Signaling pathway36
9.2STAT3, STAT1, IFNG, IL2
27
Show member pathways
Immune response CD16 signaling in NK cells58
9.2PRF1, IFNB1, IFNG, IL2
28
Show member pathways
MAPK Cascade36
Immune response Oncostatin M signaling via MAPK in human cells58
Oncostatin M Signaling Pathway36
9.1MBP, STAT1, STAT3
29
Show member pathways
Type III interferon signaling36
9.0STAT3, STAT1, IFNB1, IFNG, IL2
30
Show member pathways
Toll-like receptor signaling pathway36
Regulation of toll-like receptor signaling pathway36
9.0STAT3, STAT1, IFNB1, IFNG, IL2
31
Show member pathways
9.0HLA-DRB1, CXCL12, STAT3, STAT1, IL2
32
Show member pathways
IL27-mediated signaling events36
9.0STAT3, STAT1, IFNG, IL2, TBX21
33
Show member pathways
8.9HLA-DRB1, STAT3, STAT1, IFNG, IL2
348.9MBP, IL2, IFNG
358.8CD40LG, CCL21, CCL19, CXCL12
36
Show member pathways
8.8CXCL12, CCR5, CCL19, CCL21
37
Show member pathways
8.7HLA-DRB1, STAT3, STAT1, IFNB1, IFNG, IL2
38
Show member pathways
8.7HLA-DRB1, STAT3, STAT1, IFNB1, IFNG, IL2
39
Show member pathways
Apoptosis and survival Lymphotoxin beta receptor signaling58
8.7CXCL12, CCL19, CCL21, IL2
40
Show member pathways
8.6HLA-DRB1, PRF1, CXCL12, IFNG, IL2, CD40LG
418.6TBX21, IL2, IFNG, STAT3, PRF1, HLA-DRB1
42
Show member pathways
Immune response IL 12 induced IFN gamma production58
8.4HLA-DRB1, STAT3, STAT1, CCR5, IFNG, IL2
43
Show member pathways
8.4IL2, CCL21, CCL19, CCR5, CXCL12
44
Show member pathways
8.3CXCL12, STAT3, STAT1, CCR5, CCL19, CCL21
45
Show member pathways
8.3CXCL12, STAT3, STAT1, CCR5, CCL19, CCL21
46
Show member pathways
8.2HLA-DRB1, STAT3, STAT1, CCR5, IFNG, IL2
47
Show member pathways
7.9CXCL12, STAT3, STAT1, CCR5, CCL19, CCL21
48
Show member pathways
7.9CXCL12, STAT3, STAT1, CCR5, CCL19, CCL21
49
Show member pathways
7.6CXCL12, STAT3, STAT1, CCL19, CCL21, IFNB1
50
Show member pathways
7.3CXCL12, STAT3, CCR5, CCL19, CCL21, IFNB1

Compounds for genes affiliated with Polyradiculoneuropathy

About this section

Compounds related to Polyradiculoneuropathy according to GeneCards Suite gene sharing:

(show top 50)    (show all 137)
idCompoundScoreTop Affiliating Genes
1gamma globulin439.9ALB, IFNG, CD40LG
2mdms439.7CCR5, STAT1, CXCL12
32,5-oligoadenylate439.7IFNB1, IFNG, STAT1, IL2
4retinyl palmitate43 2410.6IL2, IFNB1, STAT3
5il 10439.6IFNG, CCR5, IL2, IFNB1
6neopterin439.6IFNG, CD40LG, IFNB1, IL2
7rituximab43 49 1211.5IL2, STAT3, CXCL12, CD40LG
8mycophenolate mofetil43 49 1211.5ALB, IFNG, IL2, CD40LG
95-aza-2deoxycytidine439.5CXCL12, STAT1, IFNB1, IFNG, STAT3
10gold sodium thiomalate439.5IL2, HLA-DRB1, IFNG
11galactosylceramide439.4MBP, CCR5, CXCL12
12ccl443 2810.4IFNB1, CCL21, CCR5, CXCL12
13polyinosinic-polycytidylic acid439.4IFNG, IFNB1, IL2, STAT3, STAT1
14mezerein439.4IFNB1, IFNG, MBP
15zidovudine43 49 1211.4IL2, ALB, CXCL12, CCR5, IFNB1
16teck439.3CCL19, CCL21, CXCL12
175fluorouracil439.2IL2, IFNG, CXCL12, IFNB1, STAT3
18herbimycin a43 5910.2IFNB1, STAT1, IFNG, CD40LG, CXCL12, IL2
19larc439.2CCR5, CCL21, CCL19, CXCL12
20ifn-alpha439.2IFNB1, IL2, STAT1, STAT3, IFNG, CXCL12
21ganglioside439.1MPZ, CD40LG, MBP, PMP22
22thalidomide43 49 59 1212.1STAT3, IFNG, IL2, CD40LG
23ribavirin43 49 1210.9CCR5, STAT1, STAT3, IFNG, IL2, CD40LG
24genistein43 28 59 2 24 1213.9IFNG, IFNB1, STAT3, CD40LG, IL2, STAT1
25sb 20358043 599.9IFNB1, STAT1, STAT3, CXCL12, IFNG
26rapamycin438.9STAT3, CD40LG, IL2, IFNG, CCR5, CXCL12
27tarc438.7CCL19, IFNG, IFNB1, CCL21, CCR5, CXCL12
28ccl343 289.7CCL21, CCL19, IFNG, CXCL12, IFNB1, CCR5
29ivig438.7CCR5, IFNB1, CD40LG, MBP, ALB, IFNG
30cholesterol43 28 24 1211.7ALB, CCR5, MPZ, PRF1, CXCL12, IFNB1
31glatiramer acetate43 129.7MPZ, IFNB1, HLA-DRB1, IFNG, IL2, MBP
32actinomycin d438.7IL2, IFNG, IFNB1, CCR5, STAT1, STAT3
33dexamethasone43 49 28 1211.6IFNG, IFNB1, IL2, CCR5, STAT1, STAT3
34cisplatin43 49 59 1211.4CD40LG, MBP, STAT3, STAT1, IL2, IFNB1
35vegf438.4STAT1, CXCL12, IFNB1, IL2, CD40LG, SH2D2A
36glutamate438.4CXCL12, MPZ, HLA-DRB1, IFNB1, MBP, CCR5
37heparin43 28 24 1211.4ALB, MBP, IFNB1, CCR5, STAT3, CXCL12
38thymidine43 249.4IFNB1, CXCL12, IFNG, IL2, STAT3, MBP
39indomethacin43 28 59 1211.3IFNG, IL2, CD40LG, MBP, ALB, STAT1
40aspartate438.3IFNB1, CCR5, STAT3, PMP22, MPZ, MBP
41cyclosporin a43 28 5910.3CD40LG, IL2, IFNG, CCR5, STAT1, STAT3
42retinoic acid43 249.2PMP22, STAT3, STAT1, CCR5, IFNB1, IFNG
43alanine438.2CD40LG, HLA-DRB1, STAT3, MBP, CCR5, IFNB1
44cycloheximide438.0STAT1, MBP, IL2, IFNG, STAT3, PRF1
45arginine437.8STAT3, HLA-DRB1, CD40LG, MBP, IFNG, CCR5
46cysteine437.8IFNG, IFNB1, STAT1, ALB, MBP, CD40LG
47rantes437.5CCR5, IFNB1, IFNG, CD40LG, IL2, CCL19
48pge2437.5STAT3, CD40LG, IL2, IFNG, IFNB1, CCL21
49tyrosine437.4STAT3, CCR5, CXCL12, STAT1, MPZ, SH2D2A
50serine437.4CXCL12, PRF1, MPZ, STAT3, CD40LG, MBP

GO Terms for genes affiliated with Polyradiculoneuropathy

About this section

Cellular components related to Polyradiculoneuropathy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1compact myelinGO:00432189.5MBP, PMP22
2external side of plasma membraneGO:00098979.0HLA-DRB1, CXCL12, CCR5, IFNG, CD40LG
3extracellular spaceGO:00056157.6CD40LG, CXCL12, CCL19, CCL21, IFNB1, IFNG
4extracellular regionGO:00055767.1PRF1, CXCL12, CCL19, CCL21, IFNB1, IFNG

Biological processes related to Polyradiculoneuropathy according to GeneCards Suite gene sharing:

(show all 29)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of metanephric nephron tubule epithelial cell differentiationGO:007230810.3IFNG, STAT1
2negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesisGO:000334010.3IFNG, STAT1
3positive regulation of monocyte chemotaxisGO:009002610.2CXCL12, CCR5
4regulation of interferon-gamma-mediated signaling pathwayGO:006033410.0IFNG, STAT1
5interferon-gamma-mediated signaling pathwayGO:00603339.9IFNG, STAT1, HLA-DRB1
6positive regulation of isotype switching to IgG isotypesGO:00483049.9IFNG, IL2, TBX21
7positive regulation of peptidyl-serine phosphorylation of STAT proteinGO:00331419.8IFNB1, IFNG
8positive regulation of interleukin-12 productionGO:00327359.7CD40LG, IFNG, CCL19
9defense response to virusGO:00516079.7PRF1, STAT1, IFNB1, IFNG
10cell surface receptor signaling pathwayGO:00071669.7IFNG, IFNB1, CCR5
11positive regulation of glycoprotein biosynthetic processGO:00105609.7CCL21, CCL19
12immunological synapse formationGO:00017719.7CCL21, CCL19
13establishment of T cell polarityGO:00017689.6CCL19, CCL21
14positive regulation of interleukin-1 beta secretionGO:00507189.6CCL19, IFNG
15response to prostaglandin EGO:00346959.6CCL19, CCL21
16positive regulation of dendritic cell antigen processing and presentationGO:00026069.6CCL19, CCL21
17positive regulation of cell motilityGO:020001479.6CCL21, CCL19
18natural killer cell activationGO:00301019.6IFNB1, IL2
19positive regulation of chemotaxisGO:00509219.5CCL19, CCL21
20cytokine-mediated signaling pathwayGO:00192219.5HLA-DRB1, STAT3, STAT1, IFNB1, IFNG
21positive regulation of receptor-mediated endocytosisGO:00482609.5CCL19, CCL21
22negative regulation of leukocyte apoptotic processGO:020001079.5CCL21, CCL19, CXCL12
23dendritic cell chemotaxisGO:00024079.4CCL21, CCL19, CCR5
24positive regulation of neutrophil chemotaxisGO:00900239.4CCL19, CCL21
25response to virusGO:00096159.3CXCL12, CCL19, IFNB1, IFNG, TBX21
26T cell costimulationGO:00312959.3CCL21, CCL19, HLA-DRB1
27positive regulation of transcription from RNA polymerase II promoterGO:00459449.2IL2, IFNG, IFNB1, STAT1, STAT3
28inflammatory responseGO:00069549.1CD40LG, CCL21, CCL19, CCR5
29immune responseGO:00069557.7MBP, IL2, CCL21, CCL19, CCR5, CXCL12

Molecular functions related to Polyradiculoneuropathy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1CCR5 chemokine receptor bindingGO:00317309.6STAT1, STAT3
2fatty acid bindingGO:00055049.6ALB, PMP2
3CCR7 chemokine receptor bindingGO:00317329.4CCL21, CCL19
4cytokine activityGO:00051259.3IFNB1, IFNG, IL2, CD40LG
5chemokine receptor bindingGO:00423799.2CCL21, CCL19, CXCL12
6chemokine activityGO:00080099.0CCL21, CCL19, CXCL12

Products for genes affiliated with Polyradiculoneuropathy

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Polyradiculoneuropathy

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet