MCID: PLY020
MIFTS: 54

Polyradiculoneuropathy malady

Neuronal diseases category

Summaries for Polyradiculoneuropathy

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Wikipedia:64 Polyradiculoneuropathy describes a condition in which polyneuropathy and polyradiculopathy occur... more...

MalaCards based summary: Polyradiculoneuropathy is related to neuropathy and chronic inflammatory demyelinating polyneuropathy. An important gene associated with Polyradiculoneuropathy is PMP22 (peripheral myelin protein 22), and among its related pathways are Interferon Pathway and Type II interferon signaling (IFNG). The compounds gamma globulin and 2,5-oligoadenylate have been mentioned in the context of this disorder. Affiliated tissues include t cells, spinal cord and brain, and related mouse phenotypes are muscle and digestive/alimentary.

Aliases & Classifications for Polyradiculoneuropathy

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Sources:
9Disease Ontology, 44Novoseek, 61UMLS, 34MeSH, 56SNOMED-CT
See all sources

Polyradiculoneuropathy, Aliases & Descriptions:

Name: Polyradiculoneuropathy 9 44 61


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


External Ids:

Disease Ontology9 DOID:4308
SNOMED-CT56 128078004
MeSH34 D011129

Related Diseases for Polyradiculoneuropathy

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Diseases related to Polyradiculoneuropathy via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 178)
idRelated DiseaseScoreTop Affiliating Genes
1neuropathy30.8MPZ, MBP, ALB, PMP22
2chronic inflammatory demyelinating polyneuropathy30.7IFNB1, CCR5, PMP22, MPZ
3hereditary neuropathy with liability to pressure palsies30.7PMP22
4hereditary neuropathies30.5MPZ, PMP22
5hepatitis30.5CD40LG, STAT1, IFNB1, CXCL12
6glomerulonephritis30.4CD40LG, CCR5, ALB
7membranous glomerulonephritis30.4ALB, CCR5
8polyneuropathy30.4PMP22, CD40LG, MBP, MPZ
9viral hepatitis30.3IFNB1, STAT1, HLA-DRB1
10optic neuritis30.3IFNB1, MPZ, MBP
11diabetes mellitus30.2HLA-DRB1, CD40LG, ALB, PMP22
12neuritis30.1MPZ, MBP, PMP22, PMP2
13myasthenia gravis30.1IL2, MBP, CCR5, IFNG
14hepatitis b30.1CCR5, IFNG, ALB, HLA-DRB1
15systemic lupus erythematosus30.0CD40LG, HLA-DRB1, IL2, IFNG, STAT1, IFNB1
16eosinophilia30.0IFNG, IL2, STAT1
17malaria30.0ALB, IFNG, HLA-DRB1
18inflammatory bowel disease29.9STAT3, CCR5, IFNG, STAT1
19influenza29.9IFNB1, CCL19, CCR5, STAT1, IFNG
20guillain-barre syndrome29.9PMP22, CD40LG, MBP, PMP2, MPZ, CCR5
21type 1 diabetes mellitus29.9HLA-DRB1, CCR5, ALB
22connective tissue disease29.8CD40LG, HLA-DRB1, IL2, ALB
23psoriasis29.7IL2, HLA-DRB1, STAT3, IFNG
24graft versus host disease29.7IL2, HLA-DRB1, CXCL12, CCR5, IFNG
25leukemia29.2HLA-DRB1, IFNB1, STAT1, STAT3, CXCL12, IL2
26multiple sclerosis28.7STAT1, CXCL12, MPZ, SH2D2A, HLA-DRB1, IFNB1
27chronic inflammatory demyelinating polyradiculoneuropathy11.1
28periapical granuloma10.5CCR5
29charcot-marie-tooth neuropathy type 1a10.5PMP22, MPZ
30acute disseminated encephalomyelitis10.5MBP
31charcot-marie-tooth disease type 410.5MPZ, PMP22
32aplastic anemia10.5IFNG
33inherited peripheral neuropathy10.5MPZ, PMP22
34brachial plexus neuropathy10.5MPZ, PMP22
35tooth disease10.5MPZ, PMP22
36hemorrhagic fever10.5CD40LG
37charcot-marie-tooth disease type 310.5PMP22, MPZ
38primary immunodeficiency disease10.5CD40LG
39syphilis10.5CCR5
40charcot-marie-tooth neuropathy type 110.5MPZ, PMP22
41pelizaeus-merzbacher disease10.4MBP, MPZ
42myelitis10.4MBP
43capillary leak syndrome10.4IL2
44diabetic neuropathy10.4PMP22, MPZ
45lupus erythematosus10.4
46primary progressive multiple sclerosis10.4IFNB1, MBP
47secondary progressive multiple sclerosis10.4IFNB1, MBP
48encephalitis10.3MBP, CCR5
49neuromyelitis optica10.3MBP, IFNB1
50leprosy10.3IL2, HLA-DRB1

Graphical network of the top 20 diseases related to Polyradiculoneuropathy:



Diseases related to polyradiculoneuropathy

Symptoms for Polyradiculoneuropathy

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Drugs & Therapeutics for Polyradiculoneuropathy

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Drug clinical trials:

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Search NIH Clinical Center for Polyradiculoneuropathy

Genetic Tests for Polyradiculoneuropathy

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Anatomical Context for Polyradiculoneuropathy

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MalaCards organs/tissues related to Polyradiculoneuropathy:

32
T cells, Spinal cord, Brain, Tongue, Kidney, Thyroid, Bone, Thymus, Heart, Liver, Lung, Skin, B cells, Pituitary

Animal Models for Polyradiculoneuropathy or affiliated genes

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Publications for Polyradiculoneuropathy

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Articles related to Polyradiculoneuropathy:

(show top 50)    (show all 440)
idTitleAuthorsYear
1
Progressive bilateral ptosis in a patient with midbrain metastasis and chronic inflammatory demyelinating polyradiculoneuropathy. (24594646)
2014
2
SjAPgren's syndrome associated chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) treated with autologous and subsequently allogeneic haematopoietic SCT (HSCT). (23503533)
2013
3
Chronic inflammatory demyelinating polyradiculoneuropathy in a patient with Crohn's disease. (23291687)
2013
4
Chronic inflammatory demyelinating polyradiculoneuropathy in a patient with systemic lupus erythematosus and good outcome with rituximab treatment. (21922339)
2012
5
CD8+ T-cell immunity in chronic inflammatory demyelinating polyradiculoneuropathy. (22238416)
2012
6
Chronic inflammatory demyelynating polyradiculoneuropathy in childhood and response to IVIg. (24391437)
2011
7
Brachial and lumbar plexuses in chronic inflammatory demyelinating polyradiculoneuropathy: MRI assessment including apparent diffusion coefficient. (20405114)
2011
8
Pulsed high-dose dexamethasone versus standard prednisolone treatment for chronic inflammatory demyelinating polyradiculoneuropathy (PREDICT study): a double-blind, randomised, controlled trial. (20133204)
2010
9
Understanding the consequences of chronic inflammatory demyelinating polyradiculoneuropathy from impairments to activity and participation restrictions and reduced quality of life: the ICE study. (21040143)
2010
10
A case of acute polyradiculoneuropathy, drug-induced hypersensitivity, and HHV-6 infection. (19273829)
2009
11
Acute polyradiculoneuropathy following wasp sting. (19934578)
2009
12
Intravenous immunoglobulin for chronic inflammatory demyelinating polyradiculoneuropathy. (19160200)
2009
13
Chronic inflammatory demyelinating polyradiculoneuropathy: a role for haematopoietic stem cell transplantation? (18958756)
2008
14
Rituximab therapy in chronic inflammatory demyelinating polyradiculoneuropathy with anti-SGPG IgM antibody. (16814550)
2006
15
European Federation of Neurological Societies/Peripheral Nerve Society guideline on management of chronic inflammatory demyelinating polyradiculoneuropathy: report of a joint task force of the European Federation of Neurological Societies and the Peripheral Nerve Society. (16643309)
2006
16
Chronic inflammatory demyelinating polyradiculoneuropathy: new views and guidelines. (16221282)
2005
17
Antibodies to peripheral nerve myelin proteins in chronic inflammatory demyelinating polyradiculoneuropathy. (15958128)
2005
18
T cell reactivity to P0, P2, PMP-22, and myelin basic protein in patients with Guillain-Barre syndrome and chronic inflammatory demyelinating polyradiculoneuropathy. (16170091)
2005
19
Chronic inflammatory demyelinating polyradiculoneuropathy: MRI study of brain and spinal cord. (15753438)
2005
20
Chronic inflammatory demyelinating polyradiculoneuropathy in patients with liver transplantation. (15372442)
2004
21
Diffuse spinal and intercostal nerve involvement in chronic inflammatory demyelinating polyradiculoneuropathy: MRI findings. (16440223)
2003
22
Chronic inflammatory demyelinating polyradiculoneuropathy in diabetic patients. (12661048)
2003
23
Waldenstrom's Macroglobulinaemia Presenting as Demyelinating Polyradiculoneuropathy. (24326654)
2002
24
Proposed revised electrophysiological criteria for chronic inflammatory demyelinating polyradiculoneuropathy. (11754181)
2002
25
Corticosteroids for chronic inflammatory demyelinating polyradiculoneuropathy. (11869620)
2002
26
Randomized controlled trial of IVIg in untreated chronic inflammatory demyelinating polyradiculoneuropathy. (11222785)
2001
27
Inflammatory polyradiculoneuropathy with spinal cord involvement and lethal [correction of letal] outcome after hepatitis B vaccination. (11412876)
2001
28
Chronic inflammatory demyelinating polyradiculoneuropathy with histologically proven optic neuritis. (11484826)
2001
29
Ataxic form of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). (10809947)
2000
30
Chronic inflammatory demyelinating polyradiculoneuropathy and severe peripheral oedema: a renal explanation. (10844803)
2000
31
Chronic inflammatory demyelinating polyradiculoneuropathy: a prevalence study in south east England. (10209187)
1999
32
Acute inflammatory demyelinating polyradiculoneuropathy associated with hyperIgEemia and atopic dermatitis. (9562273)
1998
33
Anti-GQ1b and anti-GT1a IgG antibodies in a patient with acute demyelinating polyradiculoneuropathy without ophthalmoplegia. (9328270)
1997
34
A novel trial design to study the effect of intravenous immunoglobulin in chronic inflammatory demyelinating polyradiculoneuropathy. (8936360)
1996
35
Acute inflammatory demyelinating polyradiculoneuropathy following antirabies vaccine. (9251443)
1996
36
Long-term treatment of chronic inflammatory demyelinating polyradiculoneuropathy with plasma exchange or intravenous immunoglobulin. (7633875)
1995
37
Glomerulonephritis associated with inflammatory demyelinating polyradiculoneuropathy: a case report and review of the literature. (8502319)
1993
38
Nerve root enhancement with MRI in inflammatory demyelinating polyradiculoneuropathy. (8451012)
1993
39
Prognosis in long-term immunosuppressive treatment of refractory chronic inflammatory demyelinating polyradiculoneuropathy. (1738011)
1992
40
Chronic inflammatory demyelinating polyradiculoneuropathy associated with Evans' syndrome. (1341469)
1992
41
Chronic inflammatory demyelinating polyradiculoneuropathy: comparison of patients with and without an associated monoclonal gammopathy. (1603342)
1992
42
Acquired factor VIII deficiency and polyradiculoneuropathy. (1901137)
1991
43
Evoked potentials suggest cranial nerves and CNS involvement in chronic relapsing polyradiculoneuropathy. (2731562)
1989
44
Polyradiculoneuropathy in transfusion-associated AIDS and dorsal root pathology. (2928972)
1989
45
Class and IgG subclass distribution of antibodies against peripheral nerve myelin in sera from patients with inflammatory demyelinating polyradiculoneuropathy. (2464267)
1988
46
Absence of antimyelin antibodies and serum demyelinating factors in most patients with chronic inflammatory demyelinating polyradiculoneuropathy. (3267485)
1988
47
Fulminant leukemic polyradiculoneuropathy in a case of B-cell prolymphocytic leukemia. A clinicopathologic report. (3040217)
1987
48
Idiopathic inflammatory polyradiculoneuropathy: evaluation of clinical and laboratory data and therapeutic considerations. (6862843)
1983
49
British multicentre trial of plasma exchange in acute inflammatory polyradiculoneuropathy (AIP). (6757939)
1982
50
Polyradiculoneuropathy in Addison's disease. Case report and review of literature. (558557)
1977

Variations for Polyradiculoneuropathy

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Expression for genes affiliated with Polyradiculoneuropathy

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Expression patterns in normal tissues for genes affiliated with Polyradiculoneuropathy

Search GEO for disease gene expression data for Polyradiculoneuropathy.

Pathways for genes affiliated with Polyradiculoneuropathy

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Pathways related to Polyradiculoneuropathy according to GeneCards/GeneDecks:

(show top 50)    (show all 58)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.7STAT1, IFNG, IFNB1
29.7IFNG, STAT1, IFNB1
3
Show member pathways
Transcription NF kB signaling pathway59
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response59
9.7STAT1, IFNB1, IFNG
4
Show member pathways
9.6IFNG, STAT3, STAT1
5
Show member pathways
Development Thrombopoetin signaling via JAK STAT pathway59
9.6STAT3, IFNG, STAT1
69.6STAT1, IFNG, STAT3
7
Show member pathways
IFN-gamma pathway37
9.6STAT1, STAT3, IFNG
89.6HLA-DRB1, CXCL12, IFNG
9
Show member pathways
9.5IL2, STAT1, STAT3
109.5IL2, IFNG, IFNB1
119.5CD40LG, IFNG, IL2
129.5STAT1, SH2D2A, STAT3
139.5PRF1, IFNG, STAT3
149.4HLA-DRB1, STAT1, IFNB1, IFNG
159.4STAT1, CXCL12, HLA-DRB1, STAT3
16
Show member pathways
Ras signaling in the CD4+ TCR pathway37
9.4IFNG, PRF1, IL2
17
Show member pathways
9.4CCR5, STAT1, STAT3, IFNG
189.3IL2, TBX21, IFNG, STAT1
19
Show member pathways
Calcium signaling in the CD4+ TCR pathway37
9.3CD40LG, TBX21, IFNG, IL2
20
Show member pathways
9.3CXCL12, STAT1, IL2, STAT3
219.3MPZ, MBP, PMP22
22
Show member pathways
Immune response IL 22 signaling pathway59
G protein signaling N RAS regulation pathway59
9.3STAT1, STAT3, HLA-DRB1, IL2
239.3IFNB1, IL2, HLA-DRB1, IFNG
24
Show member pathways
BCR signaling pathway37
TCR Signaling Pathway37
9.2CD40LG, IL2, IFNG, CCR5
25
Show member pathways
IL-2 Signaling pathway37
9.2IL2, IFNG, STAT1, STAT3
26
Show member pathways
IL23-mediated signaling events37
Immune response IL 10 signaling pathway59
Angiopoietin receptor Tie2-mediated signaling37
Development PDGF signaling via STATs and NF kB59
Development Angiopoietin Tie2 signaling59
9.2STAT1, IFNG, STAT3, IL2
27
Show member pathways
Immune response CD16 signaling in NK cells59
9.2IFNB1, IL2, PRF1, IFNG
28
Show member pathways
MAPK Cascade37
Immune response Oncostatin M signaling via MAPK in human cells59
Oncostatin M Signaling Pathway37
9.1STAT3, STAT1, MBP
29
Show member pathways
Type III interferon signaling37
9.0IFNB1, STAT3, IFNG, IL2, STAT1
30
Show member pathways
Toll-like receptor signaling pathway37
Regulation of toll-like receptor signaling pathway37
9.0IFNB1, STAT3, STAT1, IFNG, IL2
31
Show member pathways
9.0IL2, STAT3, CXCL12, HLA-DRB1, STAT1
32
Show member pathways
IL27-mediated signaling events37
9.0IL2, STAT3, TBX21, STAT1, IFNG
33
Show member pathways
8.9IL2, IFNG, HLA-DRB1, STAT3, STAT1
348.9IFNG, IL2, MBP
358.8CCL21, CD40LG, CCL19, CXCL12
36
Show member pathways
8.8CXCL12, CCR5, CCL19, CCL21
37
Show member pathways
8.7IFNG, STAT1, IL2, IFNB1, STAT3, HLA-DRB1
38
Show member pathways
8.7STAT3, HLA-DRB1, STAT1, IFNB1, IFNG, IL2
39
Show member pathways
Apoptosis and survival Lymphotoxin beta receptor signaling59
8.7IL2, CXCL12, CCL21, CCL19
40
Show member pathways
8.6CXCL12, CD40LG, HLA-DRB1, IL2, IFNG, PRF1
418.6PRF1, TBX21, STAT3, IFNG, HLA-DRB1, IL2
42
Show member pathways
Immune response IL 12 induced IFN gamma production59
8.4TBX21, IL2, IFNG, CCR5, STAT1, STAT3
43
Show member pathways
8.4IL2, CCR5, CXCL12, CCL19, CCL21
44
Show member pathways
8.3CXCL12, CCL21, STAT3, CCL19, STAT1, CCR5
45
Show member pathways
8.3STAT3, CCL21, CXCL12, STAT1, CCR5, CCL19
46
Show member pathways
8.2HLA-DRB1, STAT3, STAT1, CD40LG, TBX21, IL2
47
Show member pathways
7.9CCL19, CXCL12, STAT3, STAT1, IL2, CCR5
48
Show member pathways
7.9STAT3, CXCL12, CCL19, STAT1, IL2, CCL21
49
Show member pathways
7.6STAT1, CXCL12, CCL19, IL2, IFNG, CCL21
50
Show member pathways
7.3CD40LG, IL2, IFNG, CCL19, CCR5, STAT3

Compounds for genes affiliated with Polyradiculoneuropathy

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Compounds related to Polyradiculoneuropathy according to GeneCards/GeneDecks:

(show top 50)    (show all 137)
idCompoundScoreTop Affiliating Genes
1gamma globulin449.9IFNG, ALB, CD40LG
22,5-oligoadenylate449.7STAT1, IFNB1, IL2, IFNG
3retinyl palmitate44 2510.6STAT3, IL2, IFNB1
4il 10449.6IFNB1, CCR5, IL2, IFNG
5neopterin449.6IFNB1, IFNG, IL2, CD40LG
6rituximab44 50 1211.5IL2, CD40LG, CXCL12, STAT3
7mycophenolate mofetil44 50 1211.5IL2, ALB, IFNG, CD40LG
85-aza-2deoxycytidine449.5STAT3, IFNG, IFNB1, STAT1, CXCL12
9gold sodium thiomalate449.5HLA-DRB1, IFNG, IL2
10galactosylceramide449.4MBP, CCR5, CXCL12
11ccl444 2910.4CCR5, CXCL12, IFNB1, CCL21
12polyinosinic-polycytidylic acid449.4IFNB1, STAT3, IL2, IFNG, STAT1
13mezerein449.4MBP, IFNB1, IFNG
14auranofin29 44 60 1212.4IFNG, IL2, ALB
15zidovudine44 50 1211.4ALB, IFNB1, IL2, CCR5, CXCL12
16teck449.3CCL21, CCL19, CXCL12
175fluorouracil449.2IFNB1, IFNG, IL2, STAT3, CXCL12
18herbimycin a44 6010.2IL2, CXCL12, STAT1, IFNB1, IFNG, CD40LG
19larc449.2CCL21, CCL19, CCR5, CXCL12
20ifn-alpha449.2IFNG, IFNB1, STAT1, STAT3, IL2, CXCL12
21ganglioside449.1CD40LG, PMP22, MPZ, MBP
22thalidomide44 50 60 1212.1IFNG, IL2, CD40LG, STAT3
23ribavirin44 50 1210.9CCR5, STAT1, STAT3, IFNG, IL2, CD40LG
24genistein44 29 60 3 25 1213.9CXCL12, STAT3, STAT1, IFNG, IFNB1, CD40LG
25sb 20358044 609.9CXCL12, STAT3, STAT1, IFNB1, IFNG
26rapamycin448.9CCR5, IFNG, IL2, CD40LG, STAT1, STAT3
27tarc448.7CCL21, CXCL12, IFNB1, CCL19, CCR5, IFNG
28ccl344 299.7IFNG, IFNB1, CCR5, CCL19, CCL21, CXCL12
29ivig448.7CD40LG, CCR5, IFNB1, IFNG, MBP, ALB
30cholesterol44 29 25 1211.7MPZ, PRF1, STAT3, STAT1, CCR5, IFNB1
31glatiramer acetate44 129.7MPZ, IFNB1, IFNG, IL2, MBP, HLA-DRB1
32actinomycin d448.7IFNG, IL2, CD40LG, IFNB1, CCR5, STAT1
33dexamethasone44 50 29 1211.6CD40LG, STAT1, IL2, IFNG, CXCL12, STAT3
34cisplatin44 50 60 1211.4CD40LG, STAT3, STAT1, MBP, IFNB1, IL2
35vegf448.4STAT1, IFNB1, IFNG, CD40LG, STAT3, IL2
36glutamate448.4MBP, IFNB1, CCR5, CXCL12, MPZ, HLA-DRB1
37heparin44 29 25 1211.4MBP, ALB, CCR5, STAT3, CXCL12, IFNB1
38thymidine44 259.4MBP, IL2, STAT3, IFNG, CXCL12, IFNB1
39indomethacin44 29 60 1211.3STAT1, IFNB1, IFNG, IL2, MBP, ALB
40aspartate448.3ALB, MBP, CD40LG, CCR5, PMP22, MPZ
41cyclosporin a44 29 6010.3IL2, IFNG, MBP, CCR5, STAT1, STAT3
42retinoic acid44 259.2MBP, STAT3, CD40LG, IFNG, IFNB1, CCR5
43alanine448.2HLA-DRB1, STAT3, IFNB1, ALB, MBP, CD40LG
44cycloheximide448.0MBP, IFNG, PRF1, CXCL12, IFNB1, IL2
45arginine447.8STAT3, CXCL12, CD40LG, MBP, IFNG, CCR5
46cysteine447.8CD40LG, MBP, ALB, IFNG, STAT3, IFNB1
47rantes447.5CCR5, IFNB1, IFNG, CD40LG, CCL19, IL2
48pge2447.5CXCL12, CD40LG, IL2, IFNG, IFNB1, CCL21
49tyrosine447.4MBP, HLA-DRB1, CCR5, SH2D2A, MPZ, CXCL12
50serine447.4PMP22, CXCL12, IL2, IFNB1, MPZ, CD40LG

GO Terms for genes affiliated with Polyradiculoneuropathy

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Cellular components related to Polyradiculoneuropathy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1compact myelinGO:0432189.5MBP, PMP22
2external side of plasma membraneGO:0098979.0CD40LG, IFNG, CCR5, CXCL12, HLA-DRB1
3extracellular spaceGO:0056157.6IFNG, CCL21, IL2, ALB, CD40LG, CCL19
4extracellular regionGO:0055767.1ALB, IL2, IFNG, IFNB1, CCL21, CCL19

Biological processes related to Polyradiculoneuropathy according to GeneCards/GeneDecks:

(show all 29)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of metanephric nephron tubule epithelial cell differentiationGO:07230810.3IFNG, STAT1
2negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesisGO:00334010.3IFNG, STAT1
3positive regulation of monocyte chemotaxisGO:09002610.2CXCL12, CCR5
4regulation of interferon-gamma-mediated signaling pathwayGO:06033410.0IFNG, STAT1
5interferon-gamma-mediated signaling pathwayGO:0603339.9IFNG, STAT1, HLA-DRB1
6positive regulation of isotype switching to IgG isotypesGO:0483049.9IFNG, IL2, TBX21
7positive regulation of peptidyl-serine phosphorylation of STAT proteinGO:0331419.8IFNB1, IFNG
8positive regulation of interleukin-12 productionGO:0327359.7CD40LG, IFNG, CCL19
9defense response to virusGO:0516079.7PRF1, STAT1, IFNB1, IFNG
10cell surface receptor signaling pathwayGO:0071669.7IFNG, IFNB1, CCR5
11positive regulation of glycoprotein biosynthetic processGO:0105609.7CCL21, CCL19
12immunological synapse formationGO:0017719.7CCL21, CCL19
13establishment of T cell polarityGO:0017689.6CCL19, CCL21
14positive regulation of interleukin-1 beta secretionGO:0507189.6CCL19, IFNG
15response to prostaglandin EGO:0346959.6CCL19, CCL21
16positive regulation of dendritic cell antigen processing and presentationGO:0026069.6CCL19, CCL21
17positive regulation of cell motilityGO:20001479.6CCL21, CCL19
18natural killer cell activationGO:0301019.6IFNB1, IL2
19positive regulation of chemotaxisGO:0509219.5CCL19, CCL21
20cytokine-mediated signaling pathwayGO:0192219.5HLA-DRB1, STAT3, STAT1, IFNB1, IFNG
21positive regulation of receptor-mediated endocytosisGO:0482609.5CCL19, CCL21
22negative regulation of leukocyte apoptotic processGO:20001079.5CCL21, CCL19, CXCL12
23dendritic cell chemotaxisGO:0024079.4CCL21, CCL19, CCR5
24positive regulation of neutrophil chemotaxisGO:0900239.4CCL19, CCL21
25response to virusGO:0096159.3CXCL12, CCL19, IFNB1, IFNG, TBX21
26T cell costimulationGO:0312959.3CCL21, CCL19, HLA-DRB1
27positive regulation of transcription from RNA polymerase II promoterGO:0459449.2IL2, IFNG, IFNB1, STAT1, STAT3
28inflammatory responseGO:0069549.1CD40LG, CCL21, CCL19, CCR5
29immune responseGO:0069557.7MBP, IL2, CCL21, CCL19, CCR5, CXCL12

Molecular functions related to Polyradiculoneuropathy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1CCR5 chemokine receptor bindingGO:0317309.6STAT1, STAT3
2fatty acid bindingGO:0055049.6ALB, PMP2
3CCR7 chemokine receptor bindingGO:0317329.4CCL21, CCL19
4cytokine activityGO:0051259.3IFNB1, IFNG, IL2, CD40LG
5chemokine receptor bindingGO:0423799.2CCL21, CCL19, CXCL12
6chemokine activityGO:0080099.0CCL21, CCL19, CXCL12

Products for genes affiliated with Polyradiculoneuropathy

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Sources for Polyradiculoneuropathy

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4CDC
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25HMDB
26ICD10
27ICD10 via Orphanet
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29IUPHAR
30KEGG
34MeSH
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39NCIt
40NDF-RT
43NINDS
44Novoseek
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