MCID: PLY020
MIFTS: 45

Polyradiculoneuropathy

Categories: Neuronal diseases

Aliases & Classifications for Polyradiculoneuropathy

MalaCards integrated aliases for Polyradiculoneuropathy:

Name: Polyradiculoneuropathy 12 52 42 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:4308
MeSH 42 D011129
SNOMED-CT 64 128078004
UMLS 69 C0032587

Summaries for Polyradiculoneuropathy

MalaCards based summary : Polyradiculoneuropathy is related to hepatitis b and lymphoma. An important gene associated with Polyradiculoneuropathy is PMP22 (Peripheral Myelin Protein 22), and among its related pathways/superpathways are TGF-Beta Pathway and Cytokine Signaling in Immune system. The drugs Antibodies and gamma-Globulins have been mentioned in the context of this disorder. Affiliated tissues include brain, skin and t cells, and related phenotypes are behavior/neurological and cellular

Wikipedia : 72 Polyradiculoneuropathy describes a condition in which polyneuropathy and polyradiculopathy occur... more...

Related Diseases for Polyradiculoneuropathy

Diseases related to Polyradiculoneuropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 222)
id Related Disease Score Top Affiliating Genes
1 hepatitis b 30.1 IFNG IL10 PRF1
2 lymphoma 29.9 ALB IFNG IL10 IL17A
3 churg-strauss syndrome 29.8 IFNG IL10 IL17A
4 dysphagia 29.1 CCL5 IFNG IL10
5 intracranial hypertension 28.6 CCL5 IFNG IL10 IL17A
6 systemic lupus erythematosus 28.2 ALB CCL5 HLA-DRB1 IFNG IL10 IL17A
7 malaria 27.5 ALB CCL5 HLA-DRB1 IFNG IL10 IL17A
8 rheumatoid arthritis 27.0 CCL5 HLA-DRB1 IFNG IL10 IL17A TNFRSF1A
9 chronic inflammatory demyelinating polyradiculoneuropathy 12.1
10 polyradiculoneuropathy associated with igg/iga/igm monoclonal gammopathy without known antibodies 11.8
11 chronic inflammatory demyelinating polyneuropathy 11.5
12 neuropathy, inflammatory demyelinating 11.1
13 guillain-barre syndrome 11.1
14 hereditary proximal myopathy with early respiratory failure 10.8 MPZ PMP22
15 chronic polyradiculoneuritis 10.8
16 conotruncal heart malformations 10.8 MPZ PMP22
17 hemiplegia alterans 10.8 MPZ PMP22
18 charcot-marie-tooth neuropathy type 4j 10.8 MPZ PMP22
19 chronic inflammatory demyelinating polyneuritis 10.8
20 subacute inflammatory demyelinating polyneuropathy 10.8
21 mental retardation, x-linked, syndromic 34 10.7 MPZ PMP22
22 eye accommodation disease 10.7 IFNG IL10
23 charcot-marie-tooth disease, type 1b 10.7 MPZ PMP22
24 charcot-marie-tooth neuropathy x 10.7 MPZ PMP22
25 primary systemic mycosis 10.6 IFNG IL17A
26 congestive heart failure 10.6 MBP MPZ PMP22
27 graft-versus-host disease, protection against 10.6 IFNG IL10
28 thelaziasis 10.6 IFNG IL10
29 neuropathy, recurrent, with pressure palsies 10.6 MBP MPZ PMP22
30 anthracosilicosis 10.6 HLA-DRB1 IFNG
31 hypoxia 10.6 MBP MPZ PMP22
32 dumping syndrome 10.6 IFNG IL10
33 mohr-tranebjaerg syndrome 10.6 MBP MPZ PMP22
34 mosaic trisomy 1 10.6 HLA-DRB1 IFNG
35 neutrophil-specific granule deficiency 10.6 IL10 IL17A
36 niemann-pick disease, type b 10.5 MBP MPZ
37 white piedra 10.5 MBP MPZ PMP22
38 hypereosinophilic syndrome 10.4 HLA-DRB1 IFNG
39 chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids 10.4 ALB IFNG IL10
40 tonsil cancer 10.4 ALB IFNG IL10
41 plantar wart 10.4 IFNG IL10
42 pulmonary hemosiderosis 10.4 HLA-DRB1 MBP MPZ
43 ethmoid sinus cancer 10.4 IFNG STAT1
44 retinal cancer 10.4 IFNG STAT3
45 gerstmann syndrome 10.4 IFNG IL10
46 combined cellular and humoral immune defects with granulomas 10.4 IFNG IL10 IL17A
47 loiasis 10.4 IFNG IL10 IL17A
48 orbital osteomyelitis 10.4 IFNG IL10 IL17A
49 balkan nephropathy 10.4 ALB IFNG IL10
50 cornea cancer 10.4 IFNG IL10 IL17A

Graphical network of the top 20 diseases related to Polyradiculoneuropathy:



Diseases related to Polyradiculoneuropathy

Symptoms & Phenotypes for Polyradiculoneuropathy

MGI Mouse Phenotypes related to Polyradiculoneuropathy:

44 (show all 15)
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.25 IFNG IL10 MBP MPZ PMP2 PMP22
2 cellular MP:0005384 10.24 ALB IFNG IL10 MBP MPZ PMP22
3 homeostasis/metabolism MP:0005376 10.22 ALB IFNG IL10 IL17A MBP MPZ
4 hematopoietic system MP:0005397 10.19 CCL5 IFNG IL10 IL17A MBP MPZ
5 immune system MP:0005387 10.16 STAT3 TNFRSF1A CCL5 IFNG IL10 IL17A
6 mortality/aging MP:0010768 10.14 ALB IFNG IL10 IL17A MBP MPZ
7 endocrine/exocrine gland MP:0005379 10.11 IL17A ALB IFNG IL10 PRF1 STAT1
8 digestive/alimentary MP:0005381 10.07 ALB IFNG IL10 IL17A STAT1 STAT3
9 liver/biliary system MP:0005370 9.98 ALB IFNG IL10 PRF1 STAT1 STAT3
10 nervous system MP:0003631 9.96 IFNG IL10 MBP MPZ PMP2 PMP22
11 muscle MP:0005369 9.91 ALB IFNG IL10 PMP22 STAT1 STAT3
12 neoplasm MP:0002006 9.87 TNFRSF1A ALB IFNG IL10 PRF1 STAT1
13 normal MP:0002873 9.7 ALB IFNG IL10 MBP PRF1 STAT1
14 reproductive system MP:0005389 9.56 IFNG IL10 MBP MPZ PMP22 PRF1
15 vision/eye MP:0005391 9.17 IFNG IL10 MBP PMP22 STAT1 STAT3

Drugs & Therapeutics for Polyradiculoneuropathy

Drugs for Polyradiculoneuropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 48)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antibodies Phase 4,Phase 3,Phase 2
2 gamma-Globulins Phase 4,Phase 3,Phase 2
3 Immunoglobulins Phase 4,Phase 3,Phase 2
4 Immunoglobulins, Intravenous Phase 4,Phase 3,Phase 2
5 Rho(D) Immune Globulin Phase 4,Phase 3,Phase 2
6
Prednisone Approved, Vet_approved Phase 3,Phase 2 53-03-2 5865
7
Mycophenolate mofetil Approved, Investigational Phase 3 128794-94-5 5281078
8
Mycophenolic acid Approved Phase 3 24280-93-1 446541
9
Glycine Approved, Nutraceutical, Vet_approved Phase 3 56-40-6 750
10 Fingolimod Hydrochloride Phase 3
11 Immunosuppressive Agents Phase 3,Phase 2
12 3,4-diaminopyridine Phase 3
13 Potassium Channel Blockers Phase 3,Phase 2
14 Anti-Inflammatory Agents Phase 3,Phase 2
15 Antineoplastic Agents, Hormonal Phase 3,Phase 2
16 glucocorticoids Phase 3,Phase 2
17 Hormone Antagonists Phase 3,Phase 2
18 Hormones Phase 3,Phase 2
19 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2
20 Pharmaceutical Solutions Phase 3,Phase 2
21 Anti-Bacterial Agents Phase 3
22 Antibiotics, Antitubercular Phase 3
23
Interferon beta-1a Approved, Investigational Phase 2 145258-61-3 6438354
24
4-Aminopyridine Approved Phase 2 504-24-5 1727
25
Folic Acid Approved, Nutraceutical, Vet_approved Phase 2 59-30-3 6037
26 Complement System Proteins Phase 2
27 Adjuvants, Immunologic Phase 2
28 Anti-Infective Agents Phase 2
29 Antiviral Agents Phase 2
30 Interferon-beta Phase 2
31 interferons Phase 2
32 Antioxidants Phase 2
33 Micronutrients Phase 2
34 Protective Agents Phase 2
35 Thioctic Acid Phase 2
36 Trace Elements Phase 2
37 Vitamin B Complex Phase 2
38 Vitamins Phase 2
39 Alpha-lipoic Acid Nutraceutical Phase 2
40 Folate Nutraceutical Phase 2
41 Vitamin B9 Nutraceutical Phase 2
42 Vaccines
43 Anticoagulants
44 Calcium, Dietary
45 Chelating Agents
46 Antibodies, Anti-Idiotypic
47 Citrate Nutraceutical
48
Citric Acid Nutraceutical, Vet_approved 77-92-9 311

Interventional clinical trials:

(show top 50) (show all 67)

id Name Status NCT ID Phase Drugs
1 IVIg for Demyelination in Diabetes Mellitus Recruiting NCT02372149 Phase 4 10% intravenous immunoglobulin (IVIg);0.9% sodium chloride
2 Alemtuzumab in Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIPD) Withdrawn NCT01757574 Phase 4 Alemtuzumab infusion
3 Evaluate Efficacy and Safety of Fingolimod 0.5 mg Orally Once Daily Versus Placebo in Chronic Inflammatory Demyelinating Polyradiculoneuropathy Patients. Completed NCT01625182 Phase 3 Fingolimod;Placebo Comparator
4 Phase III Randomized, Double-Blind, Placebo-Controlled Study of 3,4-Diaminopyridine for Demyelinating Polyneuropathy Completed NCT00004939 Phase 3 ,4-diaminopyridine
5 Phase III Multicenter Double Blind Controlled Trial of Human Immune Globulin Therapy in Previously Untreated Patients With Chronic Inflammatory Demyelinating Neuropathy Completed NCT00004286 Phase 3 immune globulin
6 Phase III Randomized, Double-Blind, Placebo-Controlled Study of Intravenous Immune Globulin for Chronic Inflammatory Demyelinating Polyneuropathy Completed NCT00004772 Phase 3 Immune globulin
7 Immune Globulin Intravenous (IGIV) For Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) Completed NCT00220740 Phase 3 Immune Globulin IV (Human), 10% Caprylate/Chromatography Purified;Albumin (Human) 25%, United States Pharmacopeia (USP)
8 Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) and Treatment With Subcutaneous Immunoglobulin (IgPro20) Completed NCT01545076 Phase 3
9 Extension Study of Maintenance Treatment With Subcutaneous Immunoglobulin (IgPro20) for Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) Completed NCT02027701 Phase 3
10 Phase III Clinical Trial of NPB-01maintenance Therapy in Patients With Chronic Inflammatory Demyelinating Polyneuropathy. Completed NCT01824251 Phase 3 NPB-01
11 Randomized Open-label Trial to Compare Efficacy and Tolerance of Corticosteroids and IVIg Completed NCT01349270 Phase 3 Immunoglobulin perfusion;Prednisone
12 Study of Efficacy and Safety of Privigen in Subjects With Chronic Inflammatory Demyelinating Polyneuropathy Completed NCT01184846 Phase 3
13 Efficacy and Safety Study of GB-0998 for Guillain-Barré Syndrome Completed NCT02342184 Phase 3 GB-0998
14 Phase III Clinical Trial of NPB-01 in Patients With Guillain-Barré Syndrome Completed NCT02221271 Phase 3 NPB-01
15 Long-Term Tolerability and Safety of HYQVIA/HyQvia in CIDP Recruiting NCT02955355 Phase 3
16 Phase III Efficacy, Safety, and Tolerability Study of HYQVIA/HyQvia and GAMMAGARD LIQUID/KIOVIG in CIDP Recruiting NCT02549170 Phase 3
17 Efficacy and Safety Study of I10E in Treatment of Patients With CIDP Recruiting NCT02293460 Phase 3 I10E
18 Efficacy and Safety Study of I10E in the Maintenance Treatment of Patients With CIDP: Extension of PRISM Study I10E-1302 Recruiting NCT02317562 Phase 3 I10E
19 Interest of Mycophenolate for CIDP Weaning Active, not recruiting NCT02494505 Phase 3 Mycophenolate Mofetil;placebo
20 Panzyga in CIDP Administered at Different Infusion Rates Not yet recruiting NCT03166527 Phase 3 Immune Globulin 10% Intravenous Solution
21 Safety and Efficacy Study of Three Different Dosages of NewGam in Patients With CIDP Terminated NCT01225276 Phase 2, Phase 3 NewGam 10%;Placebo;NewGam 10%;NewGam 10%
22 Inhibition of Complement Activation (Eculizumab) in Guillain-Barre Syndrome Study Unknown status NCT02029378 Phase 2 Eculizumab
23 Subcutaneous Immunoglobulin Treatment of Patients With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) Completed NCT01017159 Phase 2 Subcutaneous immunoglobulin
24 Safety and Efficacy of Avonex in Subjects With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) Completed NCT00099489 Phase 2 Interferon Beta-1a
25 Lipoic Acid to Treat Chronic Inflammatory Demyelinating Polyneuropathy Completed NCT00962429 Phase 2 lipoic acid
26 Intravenous Immunoglobulin (IVIg) for the Treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) Completed NCT00001287 Phase 2 intravenous immunoglobulin (IVIg)
27 Small Volume Plasma Exchange (SVPE) for Guillain-Barré Syndrome (GBS) Patients Completed NCT02780570 Phase 2
28 Assessment of Chronic Guillain-Barre Syndrome Improvement With Use of 4-aminopyridine Completed NCT00056810 Phase 2 4-aminopyridine (4-AP)
29 Prednisone Treatment for Vestibular Neuronitis Completed NCT00271791 Phase 2 Prednisone;Prednisone
30 Early Mechanical Ventilation for Guillain Barré Syndrome Completed NCT00167622 Phase 2
31 SERENDEM : MD1003 in Patients Suffering From Demyelinating Neuropathies, an Open Label Pilot Study Recruiting NCT02967679 Phase 1, Phase 2 MD1003
32 Hematopoietic Stem Cell Transplantation in Chronic Inflammatory Demyelinating Polyneuropathy Active, not recruiting NCT00278629 Phase 2
33 Pilot Study of Acthar® Gel in Chronic Inflammatory Demyelinating Neuropathy Withdrawn NCT02574962 Phase 2 H.P. Acthar® Gel
34 High-dose Cyclophosphamide for Moderate to Severe Refractory Chronic Inflammatory Demyelinating Polyneuropathy Withdrawn NCT01236456 Phase 2 Cyclophosphamide
35 A First in HumanTrial to Evaluate The Safety, Tolerability, And Pharmacokinetics Of PF-06755347 Suspended NCT03275740 Phase 1 PF-06755347;Placebo comparator
36 sCD163 & CD19 as Candidate Biomarkers in CIDP and MMN Unknown status NCT02271724
37 Prevalence of Decreased Corneal Sensation in Patients With Chronic Inflammatory Demyelinating Polyneuropathy Unknown status NCT01379833
38 Perception and Multisensory Integration in Neurological Patients Using fMRI Unknown status NCT01469858
39 Change of Nerve Conduction Properties in IVIg Dependent Neuropathies Unknown status NCT01655394
40 The Changes of Cytokines in Guillain Barré Syndrome: the Correlation With Clinical Manifestations and Skin Innervation Unknown status NCT00173199
41 Study of CIDP Patients During IVIG Treatment Completed NCT00305266 intravenous gammaglobulin
42 MRI in Diagnosing and Monitoring CIDP Completed NCT02017769
43 Effect of Resistance and Aerobic Exercise in CIDP or MMN Completed NCT02121678
44 Immunoglobulin Dosage and Administration Form in CIDP and MMN Completed NCT02111590 Immunoglobulins
45 Magnetic Resonance Diagnostics of Diabetic Peripheral Neuropathy Completed NCT01847937
46 Effects of Robotic-assisted Gait Training In Non-Ambulatory Patients After Guillain-Barré Syndrome Completed NCT02883270
47 Intravenous Immunoglobulin (IVIG) Versus Plasma Exchange (PE) for Ventilated Children With Guillain Barre Syndrome (GBS) Completed NCT01306578 IVIG
48 Safety Study of GBS Following Menactra Meningococcal Vaccination Completed NCT00575653
49 Regional Citrate Anticoagulation in Plasma Exchange Treatment Completed NCT01370200
50 Brain Computer Interface for Communication in ICU: a Feasibility Study Completed NCT01005524

Search NIH Clinical Center for Polyradiculoneuropathy

Cochrane evidence based reviews: polyradiculoneuropathy

Genetic Tests for Polyradiculoneuropathy

Anatomical Context for Polyradiculoneuropathy

MalaCards organs/tissues related to Polyradiculoneuropathy:

39
Brain, Skin, T Cells, Spinal Cord, Thyroid, Tongue, Kidney

Publications for Polyradiculoneuropathy

Articles related to Polyradiculoneuropathy:

(show top 50) (show all 509)
id Title Authors Year
1
Immunomodulatory treatment other than corticosteroids, immunoglobulin and plasma exchange for chronic inflammatory demyelinating polyradiculoneuropathy. ( 28481421 )
2017
2
Blink R1 latency utility in diagnosis and treatment assessment of polyradiculoneuropathy-organomegaly-endocrinopathy-monoclonal protein-skin changes and chronic inflammatory demyelinating polyradiculoneuropathy. ( 28646568 )
2017
3
Chronic inflammatory demyelinating polyradiculoneuropathy and anesthesia: a case series. ( 28936613 )
2017
4
Subacute demyelinating polyradiculoneuropathy complicating Epstein-Barr virus infection in GATA2 haploinsufficiency. ( 28093780 )
2017
5
Two years' long-term follow up in chronic inflammatory demyelinating polyradiculoneuropathy: efficacy of intravenous immunoglobulin treatment. ( 28382108 )
2017
6
Rituximab in refractory chronic inflammatory demyelinating polyradiculoneuropathy: report of four cases. ( 28337614 )
2017
7
Demyelinating polyradiculoneuropathy under combined BRAF/MEK inhibitors. ( 28432982 )
2017
8
Fibronectin connecting segment-1 peptide inhibits pathogenic leukocyte trafficking and inflammatory demyelination in experimental models of chronic inflammatory demyelinating polyradiculoneuropathy. ( 28215575 )
2017
9
Treatments for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): an overview of systematic reviews. ( 28084646 )
2017
10
Acute Inflammatory Demyelinating Polyradiculoneuropathy Secondary to Ifosfamide. ( 28816726 )
2017
11
Multiple Sites Ultrasonography of Peripheral Nerves in Differentiating Charcot-Marie-Tooth Type 1A from Chronic Inflammatory Demyelinating Polyradiculoneuropathy. ( 28522988 )
2017
12
Chronic inflammatory demyelinating polyradiculoneuropathy-causing myelopathy. ( 28786217 )
2017
13
Lewis-Sumner syndrome in a patient with rheumatoid arthritis: Link between rheumatoid arthritis and demyelinating polyradiculoneuropathies. ( 28363822 )
2017
14
Multiple Myeloma Associated Chronic Inflammatory Demyelinating Polyradiculoneuropathy: The Importance of Continued Surveillance. ( 28070468 )
2016
15
A case of severe chronic inflammatory demyelinating polyradiculoneuropathy with monoclonal gammopathy of undetermined significance with alternating immunoglobulin class to IgM from IgA. ( 27580763 )
2016
16
Fatigue, Pain, Anxiety and Depression in Guillain-BarrAc Syndrome and Chronic Inflammatory Demyelinating Polyradiculoneuropathy. ( 27077919 )
2016
17
Improving the management of chronic inflammatory demyelinating polyradiculoneuropathy. ( 27230584 )
2016
18
Motor unit number index (MUNIX): Is it relevant in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)? ( 26750580 )
2016
19
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP): Clinical Features, Diagnosis, and Current Treatment Strategies. ( 27902997 )
2016
20
A Bodybuilder With Weak Hands and Feet: Corticosteroid-Responsive Pure Motor Chronic Inflammatory Demyelinating Polyradiculoneuropathy Following Anabolic Steroid Use. ( 27438336 )
2016
21
Stance Postural Strategies in Patients with Chronic Inflammatory Demyelinating Polyradiculoneuropathy. ( 26977594 )
2016
22
Transcriptome Analysis of Peripheral Blood in Chronic Inflammatory Demyelinating Polyradiculoneuropathy Patients Identifies TNFR1 and TLR Pathways in the IVIg Response. ( 27175635 )
2016
23
Chronic inflammatory demyelinating polyradiculoneuropathy occurring after autologous haematopoietic stem cell transplantation for multiple sclerosis. ( 28607734 )
2016
24
Immunomodulation of inflammatory leukocyte markers during intravenous immunoglobulin treatment associated with clinical efficacy in chronic inflammatory demyelinating polyradiculoneuropathy. ( 27781132 )
2016
25
Nivolumab-induced chronic inflammatory demyelinating polyradiculoneuropathy mimicking rapid-onset Guillain-BarrAc syndrome: a case report. ( 27380808 )
2016
26
A case of chronic inflammatory demyelinating polyradiculoneuropathy after treatment with pegylated interferon I+-2a in a patient with chronic hepatitis B virus infection. ( 27680223 )
2016
27
Intravenous Immunoglobulins Lower Inflammatory Gene Expression in Skin Biopsies of Chronic Inflammatory Demyelinating Polyradiculoneuropathy Patients. ( 27286956 )
2016
28
Acute inflammatory demyelinating polyradiculoneuropathy in a newborn infant. ( 27238765 )
2016
29
Cerebral infarction following subcutaneous immunoglobulin therapy for chronic inflammatory demyelinating polyradiculoneuropathy. ( 26873805 )
2016
30
Human Endogenous Retrovirus and Neuroinflammation in Chronic Inflammatory Demyelinating Polyradiculoneuropathy. ( 27211560 )
2016
31
Pembrolizumab-Induced Demyelinating Polyradiculoneuropathy. ( 27468083 )
2016
32
Economic Evaluation of Intravenous Immunoglobulin plus Corticosteroids for the Treatment of Steroid-Resistant Chronic Inflammatory Demyelinating Polyradiculoneuropathy in Thailand. ( 27113227 )
2016
33
Giant nerves in chronic inflammatory polyradiculoneuropathy. ( 27463360 )
2016
34
Evolution of hepatitis E virus-associated meningo-polyradiculoneuropathy on ribavirin. ( 27470489 )
2016
35
Peripheral Nerve Ultrasonography in Chronic Inflammatory Demyelinating Polyradiculoneuropathy and Multifocal Motor Neuropathy: Correlations with Clinical and Neurophysiological Data. ( 27313890 )
2016
36
Chronic inflammatory demyelinating polyradiculoneuropathy: A new animal model for new therapeutic targets. ( 27838091 )
2016
37
Intravenous immunoglobulin treatment in chronic inflammatory demyelinating polyradiculoneuropathy, a time to start and a time to stop. ( 27241239 )
2016
38
A case of a 17-year-old male with neurofascin-155 antibody-positive chronic inflammatory demyelinating polyradiculoneuropathy presenting with tremor and ataxia. ( 27580761 )
2016
39
IgG4 anti-neurofascin155 antibodies in chronic inflammatory demyelinating polyradiculoneuropathy: Clinical significance and diagnostic utility of a conventional assay. ( 27852440 )
2016
40
Primary Neurolymphomatosis Presenting With Polyradiculoneuropathy Affecting One Lower Limb. ( 26301373 )
2015
41
Chronic inflammatory demyelinating polyradiculoneuropathy with cholesterol deposits in a dog. ( 26450833 )
2015
42
Acute myeloid leucaemia presenting as a rapidly progressive polyradiculoneuropathy. ( 26581698 )
2015
43
Triple-stimulation technique improves the diagnosis of chronic inflammatory demyelinating polyradiculoneuropathy. ( 25571892 )
2015
44
Maintenace therapy in chronic inflammatory demyelinating polyradiculoneuropathy. ( 26088325 )
2015
45
Plasma exchange for chronic inflammatory demyelinating polyradiculoneuropathy. ( 26305459 )
2015
46
Long-term Immunoglobulin therapy for chronic inflammatory demyelinating polyradiculoneuropathy. ( 25556954 )
2015
47
Corticosteroids for chronic inflammatory demyelinating polyradiculoneuropathy. ( 25561247 )
2015
48
Which criteria for research in chronic inflammatory demyelinating polyradiculoneuropathy? an analysis of current practice. ( 25354388 )
2015
49
Characteristic MRI features of chronic inflammatory demyelinating polyradiculoneuropathy. ( 25687202 )
2015
50
The diagnostic value of MRI in pediatric chronic inflammatory demyelinating polyradiculoneuropathy. ( 25972306 )
2015

Variations for Polyradiculoneuropathy

Expression for Polyradiculoneuropathy

Search GEO for disease gene expression data for Polyradiculoneuropathy.

Pathways for Polyradiculoneuropathy

Pathways related to Polyradiculoneuropathy according to GeneCards Suite gene sharing:

(show all 36)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.43 CCL5 IFNG IL10 IL17A STAT1 STAT3
2
Show member pathways
13.15 CCL5 HLA-DRB1 IFNG IL10 IL17A STAT1
3
Show member pathways
12.79 CCL5 IFNG IL10 STAT1 TNFRSF1A
4
Show member pathways
12.73 HLA-DRB1 IFNG IL10 IL17A PRF1 STAT1
5
Show member pathways
12.66 CCL5 HLA-DRB1 IFNG STAT1 STAT3 TNFRSF1A
6
Show member pathways
12.55 IFNG STAT1 STAT3 TNFRSF1A
7
Show member pathways
12.53 HLA-DRB1 IFNG IL10 TNFRSF1A
8
Show member pathways
12.51 IFNG IL10 IL17A STAT1 STAT3
9
Show member pathways
12.38 HLA-DRB1 IFNG IL10 IL17A STAT1 STAT3
10 12.23 HLA-DRB1 IFNG IL10 STAT3
11
Show member pathways
12.15 IFNG IL10 STAT1 STAT3
12 12.12 IFNG STAT1 STAT3 TNFRSF1A
13
Show member pathways
12.08 IFNG IL10 IL17A STAT1
14 12.05 HLA-DRB1 IFNG IL10 STAT1 TNFRSF1A
15
Show member pathways
11.97 IFNG STAT1 STAT3
16 11.96 STAT1 STAT3 TNFRSF1A
17 11.94 IFNG STAT1 TNFRSF1A
18 11.91 IL10 IL17A STAT1 STAT3
19
Show member pathways
11.89 HLA-DRB1 IFNG STAT1 STAT3
20 11.83 MBP MPZ PMP22
21 11.83 IFNG IL10 STAT1 STAT3
22
Show member pathways
11.79 IFNG STAT1 STAT3
23
Show member pathways
11.79 IFNG IL17A STAT1 STAT3
24 11.72 IFNG IL10 IL17A
25 11.71 CCL5 HLA-DRB1 IFNG IL17A
26
Show member pathways
11.7 HLA-DRB1 IFNG IL10 STAT1 STAT3 TNFRSF1A
27 11.69 HLA-DRB1 STAT1 STAT3
28
Show member pathways
11.68 IFNG IL10 IL17A STAT1 STAT3
29 11.66 CCL5 IFNG IL10 IL17A STAT1 STAT3
30 11.57 IFNG STAT1 STAT3
31
Show member pathways
11.37 IFNG IL10 TNFRSF1A
32 11.31 CCL5 IL10 STAT3 TNFRSF1A
33 11.21 HLA-DRB1 IFNG IL10
34
Show member pathways
11.16 IFNG PRF1 STAT3
35 10.94 STAT1 STAT3
36 10.9 HLA-DRB1 IFNG PRF1 STAT3

GO Terms for Polyradiculoneuropathy

Cellular components related to Polyradiculoneuropathy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 myelin sheath GO:0043209 8.92 ALB MBP MPZ PMP2
2 compact myelin GO:0043218 8.65 PMP22

Biological processes related to Polyradiculoneuropathy according to GeneCards Suite gene sharing:

(show all 18)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription from RNA polymerase II promoter GO:0045944 9.99 IFNG IL10 IL17A STAT1 STAT3 TNFRSF1A
2 apoptotic process GO:0006915 9.93 IFNG IL17A PRF1 STAT1 TNFRSF1A
3 interferon-gamma-mediated signaling pathway GO:0060333 9.61 HLA-DRB1 IFNG STAT1
4 positive regulation of interleukin-6 secretion GO:2000778 9.58 IL17A MBP
5 response to cytokine GO:0034097 9.58 CCL5 STAT1 STAT3
6 defense response to protozoan GO:0042832 9.57 IFNG IL10
7 positive regulation of osteoclast differentiation GO:0045672 9.56 IFNG IL17A
8 negative regulation of growth of symbiont in host GO:0044130 9.55 IFNG IL10
9 inflammatory response GO:0006954 9.55 CCL5 IL10 IL17A STAT3 TNFRSF1A
10 regulation of interferon-gamma-mediated signaling pathway GO:0060334 9.52 IFNG STAT1
11 myelination GO:0042552 9.5 MBP MPZ PMP22
12 negative regulation of heterotypic cell-cell adhesion GO:0034115 9.49 IL10 MBP
13 positive regulation of metalloendopeptidase activity GO:1904685 9.48 MBP STAT3
14 positive regulation of MHC class II biosynthetic process GO:0045348 9.46 IFNG IL10
15 positive regulation of interleukin-23 production GO:0032747 9.37 IFNG IL17A
16 positive regulation of killing of cells of other organism GO:0051712 9.26 IFNG PRF1
17 immune response GO:0006955 9.17 CCL5 HLA-DRB1 IFNG IL10 IL17A MBP
18 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.13 CCL5 IFNG TNFRSF1A

Molecular functions related to Polyradiculoneuropathy according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.26 CCL5 IFNG IL10 IL17A
2 fatty acid binding GO:0005504 9.16 ALB PMP2
3 CCR5 chemokine receptor binding GO:0031730 8.62 CCL5 STAT3

Sources for Polyradiculoneuropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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