MCID: PRT018
MIFTS: 50

Portal Vein Thrombosis

Categories: Cardiovascular diseases, Blood diseases

Aliases & Classifications for Portal Vein Thrombosis

MalaCards integrated aliases for Portal Vein Thrombosis:

Name: Portal Vein Thrombosis 12 72 28 51 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:11695
ICD10 32 I81
ICD9CM 34 452
NCIt 46 C78565
SNOMED-CT 64 155455003 17920008
UMLS 69 C0155773

Summaries for Portal Vein Thrombosis

Disease Ontology : 12 A vein disease that is characterized by a blood clot that forms within the hepatic portal vein.

MalaCards based summary : Portal Vein Thrombosis is related to liver cirrhosis and hypersplenism. An important gene associated with Portal Vein Thrombosis is F2 (Coagulation Factor II, Thrombin), and among its related pathways/superpathways are Collagen chain trimerization and Response to elevated platelet cytosolic Ca2+. The drugs Benzocaine and Nadroparin have been mentioned in the context of this disorder. Affiliated tissues include liver, spleen and bone, and related phenotypes are homeostasis/metabolism and integument

Wikipedia : 72 Portal vein thrombosis, previously known as Cauchois–Eppinger–Frugoni syndrome, is a form of venous... more...

Related Diseases for Portal Vein Thrombosis

Diseases related to Portal Vein Thrombosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 274)
# Related Disease Score Top Affiliating Genes
1 liver cirrhosis 30.8 AFP F2 SERPINC1
2 hypersplenism 30.3 F2 SERPINC1
3 purpura 30.1 APOH F2 SERPINC1
4 protein c deficiency 30.1 F2 F5 MTHFR SERPINC1
5 splenic infarction 30.1 APOH F2
6 homocystinuria 29.9 F5 MTHFR SERPINC1
7 hepatic infarction 29.7 APOH F2 MTHFR SERPINC1
8 esophageal varix 29.7 AFP F2 SERPINC1
9 hepatic veno-occlusive disease 29.7 SERPINC1 SERPINE1
10 disseminated intravascular coagulation 29.7 F2 F5 SERPINC1 SERPINE1
11 polycythemia vera 29.6 F5 JAK2 SELP
12 hemophilia 29.6 F2 F7
13 hemophilia a 29.6 F5 F7
14 eclampsia 29.6 F2 F5 MTHFR SERPINC1
15 thrombosis 29.6 APOH F2 F5 JAK2 MTHFR SELP
16 thrombocytosis 29.6 F2 JAK2 SELP SERPINC1
17 protein s deficiency 29.5 APOH F2 F5 MTHFR SERPINC1
18 acute myocardial infarction 29.4 SELP SERPINC1 SERPINE1
19 antithrombin iii deficiency 29.4 APOH F2 F5 MTHFR SERPINC1
20 essential thrombocythemia 29.1 F2 JAK2 SELP SERPINE1
21 budd-chiari syndrome 28.8 APOH F2 F5 F7 JAK2 MTHFR
22 antiphospholipid syndrome 28.6 APOH F2 F5 MTHFR SELP SERPINC1
23 pulmonary embolism 28.5 APOH F2 F5 MTHFR SERPINC1 SERPINE1
24 cerebrovascular disease 28.0 F2 F5 F7 MTHFR SELP SERPINE1
25 thrombophilia 27.8 APOH F2 F5 F7 JAK2 MTHFR
26 myocardial infarction 27.7 F2 F5 F7 MTHFR SELP SERPINC1
27 pre-eclampsia 27.3 AFP APOH F2 F5 MTHFR SELP
28 stroke, ischemic 26.9 APOH F2 F5 F7 MTHFR SELP
29 primitive portal vein thrombosis 12.6
30 complement hyperactivation, angiopathic thrombosis, and protein-losing enteropathy 11.2
31 dehydrated hereditary stomatocytosis 1 with or without pseudohyperkalemia and/or perinatal edema 11.0
32 hepatocellular carcinoma 10.7
33 hepatitis 10.6
34 paracetamol poisoning 10.5 F2 F5
35 hemoglobin e disease 10.5 F2 F5
36 pancreatitis 10.4
37 portal hypertension 10.4
38 factor viii deficiency 10.4 F2 F5
39 ischemic neuropathy 10.4 F2 MTHFR
40 intestinal impaction 10.4 F2 SERPINC1
41 fournier gangrene 10.4 F2 SERPINC1
42 leech infestation 10.4 F2 SERPINC1
43 alpha-2-plasmin inhibitor deficiency 10.4 F2 SERPINC1
44 giant hemangioma 10.4 F2 SERPINC1
45 intracranial embolism 10.4 F2 SERPINC1
46 anterior spinal artery syndrome 10.3 F2 SERPINC1
47 neonatal stroke 10.3 MTHFR SERPINE1
48 may-thurner syndrome 10.3 APOH F5
49 purpura fulminans 10.3 F2 SERPINC1
50 korean hemorrhagic fever 10.3 F2 SERPINC1

Comorbidity relations with Portal Vein Thrombosis via Phenotypic Disease Network (PDN):


Active Peptic Ulcer Disease Acute Vascular Insufficiency of Intestine
Hepatic Encephalopathy Portal Hypertension

Graphical network of the top 20 diseases related to Portal Vein Thrombosis:



Diseases related to Portal Vein Thrombosis

Symptoms & Phenotypes for Portal Vein Thrombosis

MGI Mouse Phenotypes related to Portal Vein Thrombosis:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.96 MTHFR SELP SERPINC1 SERPINE1 AFP APOH
2 integument MP:0010771 9.63 JAK2 MTHFR SELP SERPINE1 F2 F5
3 liver/biliary system MP:0005370 9.43 JAK2 SELP SERPINC1 SERPINE1 AFP F5
4 mortality/aging MP:0010768 9.32 MTHFR SELP SERPINC1 SERPINE1 AFP APOH

Drugs & Therapeutics for Portal Vein Thrombosis

Drugs for Portal Vein Thrombosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 100)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Benzocaine Approved, Investigational Phase 4 1994-09-7, 94-09-7 2337
2 Nadroparin Approved, Investigational Phase 4 9041-08-1
3
Warfarin Approved Phase 4,Phase 3 81-81-2 54678486 6691
4
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
5
Dalteparin Approved Phase 4,Phase 3,Phase 2 9005-49-6
6
Dipyridamole Approved Phase 4 58-32-2 3108
7
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2 9005-49-6 46507594 772
8
Cisplatin Approved Phase 4 15663-27-1 2767 441203 84093
9
Ethiodized oil Approved, Investigational Phase 4 8008-53-5
10 tannic acid Approved, Nutraceutical Phase 4
11
Glucosamine Approved, Investigational, Nutraceutical Phase 4 3416-24-8 439213
12 Anticoagulants Phase 4,Phase 3,Phase 2
13 Bone Density Conservation Agents Phase 4
14 Calcium, Dietary Phase 4,Phase 2
15 Fibrinolytic Agents Phase 4,Phase 3,Phase 2
16 Liver Extracts Phase 4,Phase 3,Phase 2,Phase 1
17 Vasodilator Agents Phase 4,Phase 3,Phase 2
18 Antimetabolites Phase 4,Phase 3,Phase 2
19 Analgesics Phase 4
20 Analgesics, Non-Narcotic Phase 4
21 Anti-Inflammatory Agents Phase 4
22 Anti-Inflammatory Agents, Non-Steroidal Phase 4
23 Antipyretics Phase 4
24 Antirheumatic Agents Phase 4
25 calcium heparin Phase 4,Phase 3,Phase 2
26 Cyclooxygenase Inhibitors Phase 4
27 Heparin, Low-Molecular-Weight Phase 4,Phase 3,Phase 2
28 Peripheral Nervous System Agents Phase 4
29 Phosphodiesterase Inhibitors Phase 4
30 Platelet Aggregation Inhibitors Phase 4,Phase 2
31 Pharmaceutical Solutions Phase 4
32 Glucuronyl glucosamine glycan sulfate Phase 4
33 Hypoglycemic Agents Phase 4
34 Hypolipidemic Agents Phase 4,Phase 3
35 Lipid Regulating Agents Phase 4,Phase 3
36
Norfloxacin Approved Phase 3 70458-96-7 4539
37
Propranolol Approved, Investigational Phase 3 525-66-6 4946
38
Simvastatin Approved Phase 3 79902-63-9 54454
39
Rivaroxaban Approved Phase 3 366789-02-8
40
Sorafenib Approved, Investigational Phase 3,Phase 2 284461-73-0 216239 406563
41
Apixaban Approved Phase 3 503612-47-3 10182969
42 Adrenergic Agents Phase 3
43 Adrenergic Antagonists Phase 3
44 Adrenergic beta-Antagonists Phase 3
45 Anti-Arrhythmia Agents Phase 3
46 Anti-Bacterial Agents Phase 3
47 Antihypertensive Agents Phase 3
48 Anti-Infective Agents Phase 3
49 Cytochrome P-450 CYP1A2 Inhibitors Phase 3
50 Cytochrome P-450 Enzyme Inhibitors Phase 3

Interventional clinical trials:

(show top 50) (show all 64)

# Name Status NCT ID Phase Drugs
1 The Effect of Anticoagulation After Endoscopic Therapy in Cirrhotic Patients With Portal Vein Thrombosis Unknown status NCT02398357 Phase 4 Nadroparin Calcium and Warfarin
2 Warfarin Prevents Portal Vein Thrombosis in Patients After Laparoscopic Splenectomy and Azygoportal Disconnection Completed NCT02247414 Phase 4 Warfarin;Dipyridamole;Aspirin;Low Molecular Weight Heparin
3 Outcome of Transarterial Chemo-embolization (TACE) in Hepatocellular Carcinoma Patients With Partial Portal Vein Thrombosis Completed NCT03007212 Phase 4
4 A Clinical Trial of the Vessel Sealing System (LigaSure) in Azygoportal Disconnection and Splenectomy in Patients With Portal Hypertension Completed NCT00965744 Phase 4
5 Warfarin Prevents Portal Vein Thrombosis in Liver Cirrhotic Patients With Hypersplenism After Laparoscopic Splenectomy Recruiting NCT02238444 Phase 4 Warfarin;Dipyridamole;Aspirin;Low Molecular Weight Heparin
6 The Effect of Anticoagulation in Cirrhotic Patients With Portal Vein Thrombosis:A Multicenter RCT Not yet recruiting NCT02630095 Phase 4 Nadroparin Calcium and Warfarin
7 ETOS: Minimal Hepatic Encephalopathy in Childhood and Young Adult: epidemiOlogical Study and Pilot Interventional Study Unknown status NCT01798329 Phase 3
8 Probiotics for Portal Hypertension Unknown status NCT01134692 Phase 3 Propranolol, Norfloxacin, VSL#3
9 Placebo-controlled Study of NPB-06 in Patients With Portal Vein Thrombosis Completed NCT02250391 Phase 3 NPB-06;Placebo
10 Efficacy of Statin Association With Standard Treatment in Prevention of Recurrent Hemorrhage in Patient With Cirrhosis and Variceal Bleeding Completed NCT01095185 Phase 3 Simvastatin;Placebo
11 Xarelto Versus no Treatment for the Prevention of Recurrent Thrombosis in Patients With Chronic Portal Vein Thrombosis. Recruiting NCT02555111 Phase 3 Xarelto
12 Efficacy and Safety of Rivaroxaban in the Management of Acute Non-neoplastic PVT Compensated Cirrhosis Recruiting NCT03193502 Phase 3 rivaroxaban
13 TIPS for Variceal Rebleeding in Cirrhotic Patients With Occlusive Portal Vein Thrombosis and CTPV Recruiting NCT02853526 Phase 3 Propranolol;Warfarin
14 Treatment of Splanchnic Vein Thrombosis With Rivaroxaban. A Pilot, Prospective Cohort Study Recruiting NCT02627053 Phase 3 rivaroxaban
15 Multicenter Prospective Randomized Trial of the Effect of Rivaroxaban on Survival and Development of Complications of Portal Hypertension in Patients With Cirrhosis Recruiting NCT02643212 Phase 3 Rivaroxaban;Placebo
16 Efficacy Evaluation of TheraSphere to Treat Inoperable Liver Cancer With Blockage of the Portal Vein Active, not recruiting NCT01887717 Phase 3 Sorafenib
17 Safety and Efficacy of Bemiparin in the Prevention of Thrombotic Events in Hospitalized Cirrhotic Patients Active, not recruiting NCT02802605 Phase 3 Bemiparin
18 Apixaban or Dalteparin in Reducing Blood Clots in Patients With Cancer Related Venous Thromboembolism Active, not recruiting NCT02585713 Phase 3 Apixaban;Dalteparin
19 TIPS or Anticoagulation in Portal Vein Thrombosis Not yet recruiting NCT03422419 Phase 3 Heparin
20 Role of (LMWH) in Prevention of Thromboembolic Complication After (TACE) in Hepatocellular Carcinoma. Not yet recruiting NCT02715492 Phase 3 LMWH
21 Impact on Morbidity and Mortality of Prophylactic Dosing of Low Molecular Heparin in Child-Pugh B Cirrhotic Patients Suspended NCT02271295 Phase 3 Enoxaparine
22 Islet Transplantation Through an Indwelling Catheter in the Umbilical Vein Completed NCT02367534 Phase 1, Phase 2
23 Radioembolization With Yttrium-90 Microspheres for Intermediate or Advanced Hepatocellular Carcinoma Completed NCT00910572 Phase 2
24 Sorafenib Plus Hepatic Arterial Infusion Versus Sorafenib for HCC With Major Portal Vein Tumor Thrombosis Recruiting NCT03009461 Phase 2 Sorafenib
25 Pneumatic Reversible Portal Vein Diameter Modulation After Major Hepatectomy Recruiting NCT02390713 Phase 1, Phase 2
26 Complement Inhibitor Eculizumab in Clinical Islet Transplantation Recruiting NCT02727608 Phase 2 Eculizumab
27 Safety, Efficacy of Eglandin® in Living Donor Liver Transplanted Patient (PROVISION) Recruiting NCT02350218 Phase 2 Eglandin
28 Anticoagulation Post Laparoscopic Splenectomy Terminated NCT00769873 Phase 2 Enoxaparin
29 Safety Study of Autologous Stem Cell in Liver Cirrhosis Terminated NCT00382278 Phase 1, Phase 2
30 The Safety and Maximum Tolerated Dose of Axitinib in Combination With Radiotherapy for HCC Recruiting NCT02814461 Phase 1 Axitinib
31 Incidence of Venous Thromboembolic Disease and Portal Vein Thrombosis After Hepatectomy. A Cohort Study. Unknown status NCT02597218
32 Circulating Tumor Cell Genome in Peripheral Blood From Hepatocellular Carcinoma Patients Under Radiotherapy Unknown status NCT02066974
33 Liver Transplantation for Hilar Cholangiocarcinoma in Association With Neoadjuvant Radio- and Chemo-therapy Unknown status NCT01549795 Capecitabine
34 Prevalence and Predictive Factors of Portal Vein Thrombosis in Patients With Cirrhosis Completed NCT02069457
35 Efficacy and Safety of Rivaroxaban in Acute Non-neoplastic Portal Vein Thrombosis in HCV Completed NCT03201367 Rivaroxaban
36 TheraSpheres Treatment for Unresectable Hepatocarcinoma and Portal Vein Thrombosis Completed NCT01556282
37 Transjugular Intrahepatic Portosystemic Shunt (TIPS) for Prevention of Variceal Rebleeding in Cirrhotic Patients With Portal Vein Thrombosis Completed NCT01326949
38 Proteomic Analysis of Human Hepatocellular Carcinoma Completed NCT01177631
39 HEMOCC Study. Hemostasis in Cirrhotic Children. Completed NCT03244332
40 Anatomical Resection of the Liver for Hepatocellular Carcinoma: a New Ultrasound Guided Approach Completed NCT00829335
41 TIPS vs Endoscopic Therapy for Variceal Rebleeding in Cirrhotic Patients With Portal Vein Thrombosis Recruiting NCT02485184 Non-selective beta blockers;Anticoagulation
42 ADAMTS-13 LEVEL AS PREDICTIVE BIOMARKER FOR DEVELOPMENT OF PORTAL VEIN THROMBOSIS IN LIVER CIRRHOSIS (ADAPTHRO) Recruiting NCT03322696
43 Screening for Asymptomatic Portal Vein Thrombosis and Portal Hypertension in Patients With Philadelphia Negative Myeloproliferative Neoplasms Recruiting NCT01816256
44 Effect of Portal Vein Thrombosis on the Prognosis of Liver Cirrhosis Recruiting NCT02335580 Somatostatin and its analogs
45 Efficacy and Safety of Acenocoumarol for Treatment of Nontumor Portal Vein Thrombosis in Cirrhosis of Liver Recruiting NCT01631877 Enoxaparin with acenocoumarol
46 Chances in Portal System Flow After Two Bariatric Procedures Recruiting NCT02733770
47 Radiotherapy in Hepatocellular Carcinomas After Hepatectomy With Narrow Margin (<1 cm) or Portal Vein Thrombosis Recruiting NCT02309788
48 Anticoagulation for Advanced Cirrhotic Patients After TIPS Recruiting NCT03005444 Low molecular weight Heparin
49 A Study for Efficacy of Side-by-side Compared to Stent-in-stent Technique in the Endoscopic Management of Malignant Hilar Biliary Obstruction Recruiting NCT02659852
50 Donor Specific HLA Alloantibodies in Liver Transplantation Recruiting NCT02784080

Search NIH Clinical Center for Portal Vein Thrombosis

Genetic Tests for Portal Vein Thrombosis

Genetic tests related to Portal Vein Thrombosis:

# Genetic test Affiliating Genes
1 Portal Vein Thrombosis 28

Anatomical Context for Portal Vein Thrombosis

MalaCards organs/tissues related to Portal Vein Thrombosis:

38
Liver, Spleen, Bone, Colon, Myeloid, Pancreas, Neutrophil

Publications for Portal Vein Thrombosis

Articles related to Portal Vein Thrombosis:

(show top 50) (show all 716)
# Title Authors Year
1
Gastrointestinal: Duodenal variceal bleeding secondary to thrombophilia-related portal vein thrombosis. ( 29372608 )
2018
2
Regenerative nodular hyperplasia, portal vein thrombosis and primary myelofibrosis: An unusual triple association. ( 29368941 )
2018
3
The disseminated intravascular coagulation score is a novel predictor for portal vein thrombosis in cirrhotic patients with hepatitis B. ( 29178991 )
2018
4
The use of nonselective beta blockers is a risk factor for portal vein thrombosis in cirrhotic patients. ( 29451181 )
2018
5
Prospective longitudinal quality of life and survival outcomes in patients with advanced infiltrative hepatocellular carcinoma and portal vein thrombosis treated with Yttrium-90 radioembolization. ( 29329568 )
2018
6
Phase II Study of Sorafenib Combined with Concurrent Hepatic Arterial Infusion of Oxaliplatin, 5-Fluorouracil and Leucovorin for Unresectable Hepatocellular Carcinoma with Major Portal Vein Thrombosis. ( 29327075 )
2018
7
Endoscopic ultrasound-guided fine-needle aspiration of portal vein thrombosis in patients with chronic liver disease and suspicion of hepatocellular carcinoma. ( 29420366 )
2018
8
Response to Portal vein thrombosis after hepatitis C eradication with direct acting antiviral therapy. ( 29272568 )
2018
9
Low-molecular-weight heparin treatment for portal vein thrombosis in liver cirrhosis: Efficacy and the risk of hemorrhagic complications. ( 29407630 )
2018
10
Anticoagulation for Portal Vein Thrombosis in Liver Cirrhosis: Not Only Recanalize the PortalA Vein. ( 29351835 )
2018
11
Liver Atrophy and Regeneration in Non-Cirrhotic Portal Vein Thrombosis: Effect of Surgical Shunts. ( 29377486 )
2018
12
Portal vein thrombosis: yes or no on anticoagulation therapy. ( 29432256 )
2018
13
Portal Vein Thrombosis After Percutaneous Liver Biopsy. ( 28780205 )
2017
14
Liver Transplant in Patients with Portal Vein Thrombosis: Medical and Surgical Requirements. ( 28834305 )
2017
15
Postoperative inflammation as a possible cause of portal vein thrombosis after irreversible electroporation for locally advanced pancreatic cancer. ( 28932093 )
2017
16
Portal Vein Thrombosis in the Setting of Newly Diagnosed Cushing's Syndrome. ( 28491882 )
2017
17
The Epidemiology and Clinical Associations of Portal Vein Thrombosis in Hospitalized Patients With Cirrhosis: A Nationwide Analysis From the National Inpatient Sample. ( 29240852 )
2017
18
Transjugular Intrahepatic Portosystemic Shunt as the Treatment for Refractory Hepatic Hydrothorax with Portal Vein Thrombosis. ( 28776556 )
2017
19
Endovascular treatment of an unusual membranous obstruction of the inferior vena cava in Budd-Chiari syndrome complicated by mural portal vein thrombosis. ( 28483616 )
2017
20
Incidence rates and case fatality rates of portal vein thrombosis and Budd-Chiari Syndrome. ( 28180235 )
2017
21
Call for Caution: Neonatal Portal Vein Thrombosis following Enbucrilate Embolization of Placental Chorioangioma. ( 28796996 )
2017
22
The problem with incidental and chronic portal vein thrombosis. ( 28077255 )
2017
23
Liver Transplantation in Patients With Complete Portal Vein Thrombosis: Renoportal or Varicoportal Anastomosis Using Cryopreserved Vein Grafts. ( 28923632 )
2017
24
Association of Nonmalignant Portal Vein Thrombosis and Outcomes after Transjugular Intrahepatic Portosystemic Shunt in Patients with Cirrhosis. ( 28682164 )
2017
25
Clinical Impact and Risk Factors of Portal Vein Thrombosis for Patients on Wait List for Liver Transplant. ( 28621635 )
2017
26
Portal vein thrombosis after hepatitis C eradication with direct acting antiviral therapy. ( 28782876 )
2017
27
Comparison of radiation therapy modalities for hepatocellular carcinoma with portal vein thrombosis: A meta-analysis and systematic review. ( 29233562 )
2017
28
Hepatic infarction from portal vein thrombosis: A fatal consequence of acute pancreatitis. ( 28421699 )
2017
29
Transjugular local thrombolysis with/without TIPS in patients with acute non-cirrhotic, non-malignant portal vein thrombosis. ( 28733177 )
2017
30
Melioidosis with Portal Vein Thrombosis. ( 28473933 )
2017
31
Effects of Portal Vein Thrombosis on the Outcomes of Liver Cirrhosis: A Mexican Perspective. ( 29340273 )
2017
32
Portal Vein Thrombosis in Adult Omani Patients: A Retrospective Cohort Study. ( 29218132 )
2017
33
Corrigendum: Portal vein thrombosis - a primer for the general physician. ( 28765412 )
2017
34
Down-regulation of metabolic proteins in hepatocellular carcinoma with portal vein thrombosis. ( 28785178 )
2017
35
Portal Vein Thrombosis Due to an Increase in Dose of Testosterone in a Young Man with Klinefelter Syndrome. ( 29321947 )
2017
36
Successful medical management of acute mesenteric ischemia due to superior mesenteric and portal vein thrombosis in a 27-year-old man with protein S deficiency: a case report. ( 29117862 )
2017
37
Risk prediction for portal vein thrombosis in acute pancreatitis using radial basis function. ( 28943487 )
2017
38
Sport-Related Portal Vein Thrombosis: An Unusual Complication. ( 29259831 )
2017
39
Reduced microperfusion due to portal vein thrombosis: Impact on the outcome of percutaneous thermal tumor ablation. ( 28885205 )
2017
40
Reconstruction of Anomalous Portal Venous Branching in Right Lobe Living Donor Liver Transplantation and Portal vein thrombosis. ( 28834220 )
2017
41
Current status of portal vein thrombosis in Japan: Results of a questionnaire survey by the Japan Society for Portal Hypertension. ( 28902450 )
2017
42
Y90 Radioembolization for Locally Advanced Hepatocellular Carcinoma with Portal Vein Thrombosis: Long-Term Outcomes in a 185-Patient Cohort. ( 29217739 )
2017
43
Decreased portal vein velocity is predictive of the development of portal vein thrombosis: A matched case-control study. ( 28632958 )
2017
44
Antithrombin III for portal vein thrombosis in patients with liver disease: A randomized, double-blind, controlled trial. ( 28666312 )
2017
45
Asymptomatic portal vein thrombosis associated to acute cytomegalovirus infection in an immunocompetent patient. ( 28919211 )
2017
46
Portal vein thrombosis after laparoscopic total colectomy for colonic inertia. ( 28928915 )
2017
47
Screening and treatment of portal vein thrombosis in cirrhosis. ( 28081904 )
2016
48
Portal Vein Thrombosis in a Preterm Newborn with Mutation of the MTHFR and PAI-1 Genes and Sepsis by Candida parapsilosis. ( 27603544 )
2016
49
Jack 2 negative essential thrombocytosis with portal vein thrombosis and portal cavernoma formation - A case report. ( 27728317 )
2016
50
Comparison of Systemic Thrombolysis Versus Indirect Thrombolysis via the Superior Mesenteric Artery in Patients with Acute Portal Vein Thrombosis. ( 27671456 )
2016

Variations for Portal Vein Thrombosis

Expression for Portal Vein Thrombosis

Search GEO for disease gene expression data for Portal Vein Thrombosis.

Pathways for Portal Vein Thrombosis

Pathways related to Portal Vein Thrombosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.39 F2 F5 F7 SERPINC1
2
Show member pathways
12.3 APOH F2 F5 F7 JAK2 SELP
3
Show member pathways
11.89 F2 F7 MTHFR SERPINE1
4
Show member pathways
11.76 F2 F5 F7 SERPINC1 SERPINE1
5 11.5 F2 F5 F7 SERPINC1 SERPINE1
6 11.08 AFP F2
7 10.8 JAK2 SELP
8 10.5 F2 F7

GO Terms for Portal Vein Thrombosis

Cellular components related to Portal Vein Thrombosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.7 AFP APOH F2 F5 F7 SERPINC1
2 endoplasmic reticulum lumen GO:0005788 9.35 AFP F2 F5 F7 SERPINC1
3 extracellular space GO:0005615 9.23 AFP APOH F2 F5 F7 SELP

Biological processes related to Portal Vein Thrombosis according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 ER to Golgi vesicle-mediated transport GO:0006888 9.71 F2 F5 F7
2 cellular protein metabolic process GO:0044267 9.71 AFP F2 F5 SERPINC1
3 platelet degranulation GO:0002576 9.67 APOH F5 SELP SERPINE1
4 positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 9.61 F2 JAK2 SELP
5 blood coagulation GO:0007596 9.55 F2 F5 F7 JAK2 SERPINC1
6 fibrinolysis GO:0042730 9.52 F2 SERPINE1
7 signal peptide processing GO:0006465 9.51 F2 F7
8 regulation of blood coagulation GO:0030193 9.5 APOH F2 SERPINC1
9 blood coagulation, intrinsic pathway GO:0007597 9.49 APOH F2
10 negative regulation of blood coagulation GO:0030195 9.48 APOH SERPINE1
11 peptidyl-glutamic acid carboxylation GO:0017187 9.46 F2 F7
12 negative regulation of fibrinolysis GO:0051918 9.43 APOH F2 SERPINE1
13 hemostasis GO:0007599 9.26 F2 F5 F7 SERPINC1
14 positive regulation of blood coagulation GO:0030194 8.92 APOH F2 F7 SERPINE1

Molecular functions related to Portal Vein Thrombosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 receptor binding GO:0005102 9.26 F2 F7 JAK2 SERPINE1
2 lipopolysaccharide binding GO:0001530 9.16 F2 SELP
3 heparin binding GO:0008201 8.92 APOH F2 SELP SERPINC1

Sources for Portal Vein Thrombosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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