MCID: PST028
MIFTS: 59

Post-Traumatic Stress Disorder

Categories: Mental diseases, Neuronal diseases

Aliases & Classifications for Post-Traumatic Stress Disorder

MalaCards integrated aliases for Post-Traumatic Stress Disorder:

Name: Post-Traumatic Stress Disorder 12 28 40 14 69
Stress Disorders, Post-Traumatic 41
Post Traumatic Stress Disorder 72
Traumatic Neurosis 12
Ptsd 44

Classifications:



External Ids:

Disease Ontology 12 DOID:2055
ICD10 32 F43.1 F43.10
ICD9CM 34 309.81
MeSH 41 D013313
NCIt 46 C3389
SNOMED-CT 64 192415000 47505003
UMLS 69 C0038436

Summaries for Post-Traumatic Stress Disorder

MedlinePlus : 40 Post-traumatic stress disorder (PTSD) is a real illness. You can get PTSD after living through or seeing a traumatic event, such as war, a hurricane, sexual assault, physical abuse, or a bad accident. PTSD makes you feel stressed and afraid after the danger is over. It affects your life and the people around you. PTSD can cause problems like Flashbacks, or feeling like the event is happening again Trouble sleeping or nightmares Feeling alone Angry outbursts Feeling worried, guilty, or sad PTSD starts at different times for different people. Signs of PTSD may start soon after a frightening event and then continue. Other people develop new or more severe signs months or even years later. PTSD can happen to anyone, even children. Treatment may include talk therapy, medicines, or both. Treatment might take 6 to 12 weeks. For some people, it takes longer. NIH: National Institute of Mental Health

MalaCards based summary : Post-Traumatic Stress Disorder, also known as stress disorders, post-traumatic, is related to traumatic brain injury and anxiety, and has symptoms including nervousness An important gene associated with Post-Traumatic Stress Disorder is CRH (Corticotropin Releasing Hormone), and among its related pathways/superpathways are Circadian entrainment and Amphetamine addiction. The drugs Diazepam and Tramadol have been mentioned in the context of this disorder. Affiliated tissues include brain, eye and heart, and related phenotypes are homeostasis/metabolism and behavior/neurological

Disease Ontology : 12 An anxiety disorder which results from a traumatic experience that results in psychological trauma.

Wikipedia : 72 Posttraumatic stress disorder (PTSD)[note 1] is a mental disorder that can develop after a person is... more...

Related Diseases for Post-Traumatic Stress Disorder

Diseases related to Post-Traumatic Stress Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 141)
# Related Disease Score Top Affiliating Genes
1 traumatic brain injury 32.8 BDNF COMT DRD2
2 anxiety 31.3 BDNF CNR1 COMT CRH HTR2A MAOA
3 brain injury 31.1 BDNF COMT DRD2
4 chronic pain 30.4 CNR1 COMT
5 burns 30.3 CRH IL1B
6 alexithymia 30.1 COMT CRP DRD2 SLC6A4
7 drug dependence 29.9 BDNF CNR1 CRH DRD2 SLC6A4
8 generalized anxiety disorder 29.7 BDNF DRD2 HTR2A MAOA SLC6A4
9 panic disorder 29.6 BDNF COMT CRH HTR2A MAOA SLC6A4
10 substance abuse 29.6 BDNF COMT DRD2 MAOA SLC6A4
11 substance dependence 29.5 BDNF CNR1 DRD2 MAOA SLC6A4
12 borderline personality disorder 29.5 BDNF COMT FKBP5 HTR2A MAOA NR3C1
13 paranoid schizophrenia 29.5 BDNF COMT HTR2A MAOA SLC6A4
14 serotonin syndrome 29.5 HTR2A MAOA MAOB SLC6A4
15 obsessive-compulsive disorder 29.5 BDNF COMT DRD2 HTR2A MAOA SLC6A4
16 psychotic disorder 29.4 BDNF COMT DRD2 HTR2A MAOB SLC6A4
17 chronic fatigue syndrome 29.4 COMT CRH IL1B MAOA NR3C1 SLC6A4
18 personality disorder 29.2 BDNF COMT DRD2 HTR2A MAOA MAOB
19 autism 29.1 BDNF COMT DRD2 HTR2A MAOA SLC6A4
20 body mass index quantitative trait locus 11 29.1 CNR1 CRH CRP DRD2 FAAH NR3C1
21 attention deficit-hyperactivity disorder 29.0 BDNF COMT DRD2 HTR2A MAOA MAOB
22 migraine with or without aura 1 28.9 ADCYAP1 CNR1 COMT DRD2 HTR2A MAOA
23 schizophrenia 28.8 BDNF CNR1 COMT DRD2 HTR2A MAOA
24 bipolar disorder 28.8 BDNF COMT CRH DRD2 HTR2A MAOA
25 major depressive disorder 28.6 BDNF COMT CRH DRD2 FKBP5 HTR2A
26 mood disorder 28.4 BDNF COMT CRH DRD2 HTR2A MAOA
27 alcohol dependence 28.4 BDNF CNR1 COMT DRD2 FAAH HTR2A
28 multiple personality disorder 11.2
29 allergic urticaria 10.5 CRH NR3C1
30 alcohol use disorder 10.4 DRD2 SLC6A4
31 schizophreniform disorder 10.4 COMT DRD2
32 acute stress disorder 10.4
33 renal infectious disease 10.4 CRP NR3C1
34 alcohol-induced mental disorder 10.3 DRD2 SLC6A4
35 alzheimer disease 5 10.3 HTR2A SLC6A4
36 phobia, specific 10.3 COMT MAOA
37 aging 10.3
38 gilles de la tourette syndrome 10.3 BDNF COMT DRD2
39 tardive dyskinesia 10.3 COMT DRD2 HTR2A
40 cannabis abuse 10.3 BDNF CNR1
41 alcoholic psychosis 10.3 DRD2 HTR2A SLC6A4
42 episodic pain syndrome, familial, 1 10.3
43 periodic limb movement disorder 10.2 DRD2 HTR2A SLC6A4
44 bruxism 10.2 DRD2 HTR2A SLC6A4
45 social phobia 10.2 DRD2 MAOA SLC6A4
46 drug-induced mental disorder 10.2 CNR1 DRD2 HTR2A
47 drug psychosis 10.2 CNR1 DRD2 HTR2A
48 phobic disorder 10.2 COMT MAOA SLC6A4
49 brunner syndrome 10.2 COMT MAOA SLC6A4
50 toxic encephalopathy 10.2 BDNF IL1B MAOB

Comorbidity relations with Post-Traumatic Stress Disorder via Phenotypic Disease Network (PDN):


Anxiety Dysthymic Disorder
Major Depressive Disorder

Graphical network of the top 20 diseases related to Post-Traumatic Stress Disorder:



Diseases related to Post-Traumatic Stress Disorder

Symptoms & Phenotypes for Post-Traumatic Stress Disorder

UMLS symptoms related to Post-Traumatic Stress Disorder:


nervousness

MGI Mouse Phenotypes related to Post-Traumatic Stress Disorder:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.3 FAAH CNR1 FKBP5 COMT IL1B CRH
2 behavior/neurological MP:0005386 10.28 FAAH CNR1 FKBP5 COMT HTR2A CRH
3 nervous system MP:0003631 10.1 FAAH CNR1 COMT IL1B CRH ADCYAP1
4 integument MP:0010771 9.92 FAAH CNR1 CRH DRD2 BDNF SLC6A4
5 adipose tissue MP:0005375 9.91 CNR1 ADCYAP1 CRH DRD2 PREP NR3C1
6 no phenotypic analysis MP:0003012 9.7 CNR1 ADCYAP1 CRH ADCYAP1R1 DRD2 BDNF
7 normal MP:0002873 9.61 FAAH CNR1 FKBP5 CRH ADCYAP1R1 DRD2
8 renal/urinary system MP:0005367 9.17 FKBP5 COMT CRH DRD2 PREP MAOB

Drugs & Therapeutics for Post-Traumatic Stress Disorder

Drugs for Post-Traumatic Stress Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 363)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Diazepam Approved, Illicit, Investigational, Vet_approved Phase 4 439-14-5 3016
2
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
3
Dronabinol Approved, Illicit Phase 4,Phase 2,Phase 1 1972-08-3 16078 2978
4
Oxytocin Approved, Vet_approved Phase 4,Phase 2,Phase 1,Early Phase 1 50-56-6 53477758 439302
5
Fluoxetine Approved, Vet_approved Phase 4,Phase 3,Phase 1 54910-89-3 3386
6
Propranolol Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 525-66-6 4946
7
Sertraline Approved Phase 4,Phase 3,Phase 2,Phase 1 79617-96-2 68617
8
Ethanol Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 64-17-5 702
9
Topiramate Approved Phase 4,Phase 2,Phase 3 97240-79-4 5284627
10
Paroxetine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 61869-08-7 43815
11
Cycloserine Approved Phase 4,Phase 2,Phase 3 68-41-7 6234 401
12
Mifepristone Approved, Investigational Phase 4,Phase 2,Phase 1 84371-65-3 55245
13
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 51-61-6, 62-31-7 681
14
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2 1994-09-7, 94-09-7 2337
15
Citalopram Approved Phase 4,Phase 3,Phase 2 59729-33-8 2771
16
Hydrocortisone Approved, Vet_approved Phase 4,Phase 2,Phase 3 50-23-7 657311 5754
17
Norepinephrine Approved Phase 4,Phase 3,Phase 1,Early Phase 1 51-41-2 439260
18
Prazosin Approved Phase 4,Phase 3,Phase 2,Phase 1 19216-56-9 4893
19
Lorazepam Approved Phase 4 846-49-1 3958
20
Midazolam Approved, Illicit Phase 4,Phase 3,Phase 2 59467-70-8 4192
21
Ketamine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 6740-88-1 3821
22
Asenapine Approved Phase 4 85650-56-2, 65576-45-6 3001386
23
Eszopiclone Approved, Investigational Phase 4 138729-47-2 969472
24
Naltrexone Approved, Investigational, Vet_approved Phase 4,Phase 2 16590-41-3 5360515
25
Clonazepam Approved, Illicit Phase 4 1622-61-3 2802
26
Ziprasidone Approved Phase 4,Phase 3,Phase 2 146939-27-7 60854
27
Histamine Approved, Investigational Phase 4 51-45-6, 75614-87-8 774
28
Mianserin Approved, Investigational Phase 4 24219-97-4 4184
29
Mirtazapine Approved Phase 4 85650-52-8, 61337-67-5 4205
30
Memantine Approved, Investigational Phase 4 19982-08-2 4054
31
Risperidone Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 106266-06-2 5073
32
Haloperidol Approved Phase 4,Phase 3 52-86-8 3559
33
Carbon monoxide Approved, Investigational Phase 4 630-08-0 281
34
Doxazosin Approved Phase 4,Phase 2,Phase 1 74191-85-8 3157
35
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 3 437-38-7 3345
36
Guanfacine Approved, Investigational Phase 4,Phase 1 29110-47-2 3519
37
Valproic Acid Approved, Investigational Phase 4,Phase 3 99-66-1 3121
38
Vortioxetine Approved, Investigational Phase 4 508233-74-7 9966051
39
Suvorexant Approved, Investigational Phase 4 1030377-33-3
40
Minocycline Approved, Investigational Phase 4 10118-90-8 5281021
41
Levodopa Approved Phase 4 59-92-7 6047
42
Estradiol Approved, Investigational, Vet_approved Phase 4 50-28-2 5757
43
Lormetazepam Approved Phase 4 848-75-9 13314
44 tannic acid Approved, Nutraceutical Phase 4,Phase 3,Phase 2
45
Melatonin Approved, Nutraceutical, Vet_approved Phase 4 73-31-4 896
46
Butyric Acid Experimental, Investigational Phase 4,Phase 3,Phase 2 107-92-6 264
47 Adjuvants, Anesthesia Phase 4,Phase 3,Phase 2,Phase 1
48 Anesthetics Phase 4,Phase 3,Phase 2,Phase 1
49 Anesthetics, General Phase 4,Phase 3,Phase 2,Phase 1
50 Anesthetics, Intravenous Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 1218)

# Name Status NCT ID Phase Drugs
1 Transcranial Magnetic Stimulation for Post-Traumatic Stress Disorder Unknown status NCT00134446 Phase 4
2 Prevention of Posttraumatic Stress Disorder (PTSD) With Diazepam Unknown status NCT01221883 Phase 4 Diazepam
3 Tramadol Extended-Release (ER) for Posttraumatic Stress Disorder (PTSD) Unknown status NCT01517711 Phase 4 Tramadol;Placebo
4 Add on Study on Δ9-THC Treatment for Posttraumatic Stress Disorders (PTSD) Unknown status NCT00965809 Phase 4 Tetrahydrocannabinol
5 The Effect of 21-Days Intranasal Oxytocin on Patients With Post Traumatic Stress Disorder (PTSD) Unknown status NCT02336568 Phase 4 Oxytoine;PLACEBO
6 Predictors of Treatment Response to Fluoxetine in PTSD Following a Recent History of War Zone Stress Exposure Unknown status NCT00633685 Phase 4 Fluoxetine;Placebo
7 A Randomized Cross Over Trial of Two Treatments for Obstructive Sleep Apnea in Veterans With Post Traumatic Stress Disorder Unknown status NCT01535586 Phase 4
8 Effect of Propranolol on Preventing Posttraumatic Stress Disorder Completed NCT00158262 Phase 4 Propranolol;Placebo
9 An Open Label Pilot Study of Adjunctive Asenapine for the Treatment of Posttraumatic Stress Disorder Completed NCT01587118 Phase 4 Adjunctive asenapine
10 Cognitive Behavioral Therapy Versus Sertraline in the Treatment of Post-Traumatic Stress Disorder Completed NCT00391430 Phase 4 Sertraline
11 Eszopiclone for the Treatment of Posttraumatic Stress Disorder Completed NCT01605253 Phase 4 Eszopiclone;Placebo
12 Treatment for Alcoholism and Post-Traumatic Stress Disorder (Naltrexone) Completed NCT00006489 Phase 4 Naltrexone;Placebo
13 PROlonGed ExpoSure Sertraline Completed NCT01524133 Phase 4 Sertraline
14 Placebo Controled Clinical Trial Using Topiramate To Treat Posttraumatic Stress Disorder (PTSD) Patients. Completed NCT00725920 Phase 4 Topiramate;placebo control group
15 Eszopiclone for Sleep Disturbance and Nightmares in Post-Traumatic Stress Disorder Completed NCT00120250 Phase 4 Eszopiclone
16 Clonazepam and Paroxetine for Rapid Treatment of Post-Traumatic Stress Disorder Completed NCT00025740 Phase 4 clonazepam and paroxetine
17 Developing Memory Reconsolidation Blockers as Novel Posttraumatic Stress Disorder (PTSD) Treatments Completed NCT01490697 Phase 4 Mifepristone;d-Cycloserine;Placebo-matching Mifepristone;Placebo-matching d-Cycloserine (DCS)
18 Geodon (Ziprasidone) for Posttraumatic Stress Disorder Completed NCT00208208 Phase 4 Ziprasidone
19 Topiramate in the Treatment of Posttraumatic Stress Disorder in Civilians Completed NCT00208130 Phase 4 Topiramate
20 Brain Markers of Treatment Response in Post-Traumatic Stress Disorder (PTSD) Completed NCT00700999 Phase 4 Paroxetine
21 Vilazodone for the Treatment of Posttraumatic Stress Disorder Completed NCT01715519 Phase 4 Treatment (Viibryd)
22 Neural Circuits in Women With Abuse and Posttraumatic Stress Disorder Completed NCT01681849 Phase 4 Placebo;Paroxetine
23 Topiramate Treatment of Alcohol Use Disorders in Veterans With Post Traumatic Stress Disorder (PTSD): A Pilot Controlled Trial of Augmentation Therapy Completed NCT01087736 Phase 4 Topiramate
24 Combined Mirtazapine and SSRI Treatment of PTSD: A Placebo-Controlled Trial Completed NCT01178671 Phase 4 Mirtazapine;Sertraline
25 Secondary Prevention With Paroxetine vs. Placebo in Subthreshold Posttraumatic Stress Disorder (PTSD) Completed NCT00560612 Phase 4 Paroxetine;Placebo
26 Effects of Paxil CR on Neural Circuits in Posttraumatic Stress Disorder (PTSD) Completed NCT00672776 Phase 4 paroxetine;placebo
27 Topiramate in the Treatment of Post Traumatic Stress Disorder (PTSD) Completed NCT00203463 Phase 4 topiramate
28 A Psychophysiologic Study of Weakening Traumatic Combat Memories With Post-Reactivation Propranolol Completed NCT00709735 Phase 4 Propranolol;Placebo
29 Combination Treatment for Posttraumatic Stress Disorder (PTSD) After the World Trade Center (WTC) Attack Completed NCT01130103 Phase 4 Paroxetine
30 The Effect of Intranasal Oxytocin on Emphatic Abilities in Patients With Post Traumatic Stress Disorder (PTSD) Completed NCT01325168 Phase 4 syntocinon nasal spray;placebo nasal spray
31 An Open-Label Trial of Memantine for Cognitive Impairment in Patients With Post-Traumatic Stress Disorder Completed NCT02258828 Phase 4 Memantine
32 Effects of Escitalopram on Autonomic Reactivity in Post Traumatic Stress Disorder Completed NCT01271244 Phase 4 Escitalopram
33 Serotonin Selective Reuptake Inhibitor Treatment of Dual Diagnosis Post-traumatic Stress Disorder and Alcohol Problems Completed NCT02504931 Phase 4 Sertraline;Placebo
34 The Outcome of Treatment of Traumatised Refugees With Psychotherapy and/or Antidepressants Completed NCT00917397 Phase 4 Sertraline
35 Risperidone in the Treatment of PTSD in Women Survivors of Domestic Abuse and Rape Trauma Completed NCT00208182 Phase 4 Risperidone
36 Telemedicine Outreach for Post Traumatic Stress in CBOCs Completed NCT00821678 Phase 4
37 Veteran Stress and Learning Study Completed NCT00674570 Phase 4 Hydrocortisone;D-Cycloserine;Placebo
38 A Study of Sertraline to Prevent PTSD Completed NCT00182078 Phase 4 Placebo;Sertraline
39 Quetiapine Treatment for Post-Traumatic Stress Disorder (PTSD) Completed NCT00237393 Phase 4 Quetiapine;Placebo
40 The Treatment of Traumatised Refugees With Sertraline Versus Venlafaxine in Combination With Psychotherapy Completed NCT01569685 Phase 4 Venlafaxine;Sertraline
41 Evaluation of Stress Disorders Completed NCT00050804 Phase 4 sertraline
42 Veterans Individual Placement and Support Towards Advancing Recovery Completed NCT01817712 Phase 4
43 Posttraumatic Symptoms Among Toddlers and Their Parents Following Exposure to Terrorism Completed NCT00447538 Phase 4
44 Primary Care Intervention Strategy for Anxiety Disorders Completed NCT00347269 Phase 4 Psychotropic medication optimization
45 Prazosin Treatment for Combat Trauma PTSD (Post-Traumatic Stress Disorder) Nightmares and Sleep Disturbance Completed NCT00108420 Phase 4 Prazosin
46 Pilot Study of Pharmaceutical and Behavioral Interventions to Treat Anxiety Disorders Completed NCT01631682 Phase 4 Propranolol;Mifepristone;Intranasal oxytocin
47 Influence of Hydrocortisone on Immunologic Markers and Health Care Related Quality of Life in Patients After Cardiac Surgery Completed NCT00490828 Phase 4 Hydrocortisone
48 A Placebo-Controlled Study of Mirtazapine for PTSD Completed NCT00302107 Phase 4 Mirtazapine;Placebo
49 Cardiopulmonary Resuscitation Witnessing by a Relative Completed NCT01009606 Phase 4
50 Prazosin Alcohol Dependence IVR Study Completed NCT00167687 Phase 4 prazosin

Search NIH Clinical Center for Post-Traumatic Stress Disorder

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cochrane evidence based reviews: stress disorders, post-traumatic

Genetic Tests for Post-Traumatic Stress Disorder

Genetic tests related to Post-Traumatic Stress Disorder:

# Genetic test Affiliating Genes
1 Post-Traumatic Stress Disorder 28

Anatomical Context for Post-Traumatic Stress Disorder

MalaCards organs/tissues related to Post-Traumatic Stress Disorder:

38
Brain, Eye, Heart, Testes, Cortex, Lung, Prefrontal Cortex

Publications for Post-Traumatic Stress Disorder

Articles related to Post-Traumatic Stress Disorder:

(show top 50) (show all 726)
# Title Authors Year
1
Influence of early stress on memory reconsolidation: Implications for post-traumatic stress disorder treatment. ( 29352277 )
2018
2
Familial risk for psychiatric disorders in military veterans who have post-traumatic stress disorder with psychosis: a retrospective electronic record review. ( 29384891 )
2018
3
A Systematic Review of Interleukin-1I^ in Post-Traumatic Stress Disorder: Evidence from Human and Animal Studies. ( 29328883 )
2018
4
The Transcendental Meditation Program's Impact on the Symptoms of Post-traumatic Stress Disorder of Veterans: An Uncontrolled Pilot Study. ( 29401353 )
2018
5
Animal-Assisted Therapy for Post-traumatic Stress Disorder: Lessons from "Case Reports" in Media Stories. ( 29401355 )
2018
6
Cotinine: A Therapy for Memory Extinction in Post-traumatic Stress Disorder. ( 29335846 )
2018
7
Regulation of threat in post-traumatic stress disorder: Associations between inhibitory control and dissociative symptoms. ( 29409740 )
2018
8
Severe and protracted sleep disruptions in mouse model of post-traumatic stress disorder. ( 29346627 )
2018
9
Effect of Post-Traumatic Stress Disorder on Cognitive Function and Covert Hepatic Encephalopathy Diagnosis in Cirrhotic Veterans. ( 29313245 )
2018
10
Undetected post-traumatic stress disorder in secondary-care mental health services: systematic review. ( 29433609 )
2018
11
Trial of Prazosin for Post-Traumatic Stress Disorder in Military Veterans. ( 29414272 )
2018
12
Military-Tailored Yoga for Veterans with Post-traumatic Stress Disorder. ( 29415222 )
2018
13
trans-Resveratrol ameliorates anxiety-like behaviors and fear memory deficits in a rat model of post-traumatic stress disorder. ( 29373817 )
2018
14
DBS in Treatment of Post-Traumatic Stress Disorder. ( 29361705 )
2018
15
The role of negative cognitions, emotion regulation strategies, and attachment style in complex post-traumatic stress disorder: Implications for new and existing therapies. ( 29355986 )
2018
16
Comorbid insomnia and sleep apnea in Veterans with post-traumatic stress disorder. ( 29330769 )
2018
17
Cortical surface area reduction in identification of subjects at high risk for post-traumatic stress disorder: A pilot study. ( 29361837 )
2018
18
Longitudinal trajectories of post-traumatic stress disorder (PTSD) after birth and associated risk factors. ( 29331697 )
2018
19
Epigenetic alterations of the BDNF gene in combat-related post-traumatic stress disorder. ( 27886370 )
2017
20
A Study of Selected Ethnic Affiliations in the Development of Post-traumatic Stress Disorder and Other Psychopathology After a Terrorist Bombing in Nairobi, Kenya. ( 28925342 )
2017
21
Childhood adversities and post-traumatic stress disorder: evidence for stress sensitisation in the World Mental Health Surveys. ( 28935660 )
2017
22
Six Sessions of Emotional Freedom Techniques Remediate One Veteran's Combat-Related Post-Traumatic Stress Disorder. ( 28874927 )
2017
23
Comorbidity of post-traumatic stress disorder and anxiety in flood survivors: Prevalence and shared risk factors. ( 28885358 )
2017
24
A case of enterobiasis presenting as post-traumatic-stress-disorder (PTSD): a curious case of the infection with predominant mental health symptoms, presenting for the first time in the settings of a refugee camp. ( 28819532 )
2017
25
The MCP-4/MCP-1 ratio in plasma is a candidate circadian biomarker for chronic post-traumatic stress disorder. ( 28170001 )
2017
26
Secondary psychotic features in refugees diagnosed with post-traumatic stress disorder: a retrospective cohort study. ( 28056884 )
2017
27
The effect of Elettaria cardamomum extract on anxiety-like behavior in a rat model of post-traumatic stress disorder. ( 28073098 )
2017
28
Alpha-1 Acid Glycoprotein (orosomucoid): An Overlooked Piece of Post Traumatic Stress Disorder Pathology? ( 28915958 )
2017
29
Post-Traumatic Stress Disorder (PTSD) in Sexually Abused Children and Educational Status in Kenya: A Longitudinal Study. ( 29399634 )
2017
30
Dissociation between amygdala and bed nucleus of the stria terminalis during threat anticipation in female post-traumatic stress disorder patients. ( 28070973 )
2017
31
Trauma exposure and post-traumatic stress disorder in a cohort of pregnant Peruvian women. ( 28905129 )
2017
32
Impaired working memory updating affects memory for emotional and non-emotional materials the same way: evidence from post-traumatic stress disorder (PTSD). ( 28929242 )
2017
33
Effect of oleuropein on cognitive deficits and changes in hippocampal brain-derived neurotrophic factor and cytokine expression in a rat model of post-traumatic stress disorder. ( 28884427 )
2017
34
Dissociation between working memory performance and proactive interference control in post-traumatic stress disorder. ( 28077328 )
2017
35
Risk of relapse after antidepressant discontinuation in anxiety disorders, obsessive-compulsive disorder, and post-traumatic stress disorder: systematic review and meta-analysis of relapse prevention trials. ( 28903922 )
2017
36
Depression and post-traumatic stress disorder in individuals with hereditary hemorrhagic telangiectasia: A cross-sectional survey. ( 28314138 )
2017
37
Tensor decomposition-based unsupervised feature extraction identifies candidate genes that induce post-traumatic stress disorder-mediated heart diseases. ( 29322921 )
2017
38
Prolonged exposure therapy for the treatment of patients diagnosed with psychogenic non-epileptic seizures (PNES) and post-traumatic stress disorder (PTSD). ( 28038392 )
2017
39
Disrupted cortical brain network in post-traumatic stress disorder patients: a resting-state electroencephalographic study. ( 28895942 )
2017
40
Effects of vagus nerve stimulation on extinction of conditioned fear and post-traumatic stress disorder symptoms in rats. ( 28892066 )
2017
41
Mind-Body Therapy for Military Veterans with Post-Traumatic Stress Disorder: A Systematic Review. ( 28880607 )
2017
42
Risk of relapse after antidepressant discontinuation in anxiety disorders, obsessive-compulsive disorder, and post-traumatic stress disorder: systematic review and meta-analysis of relapse prevention trials. ( 28947609 )
2017
43
Risk Factors for Mild Traumatic Brain Injury and Subsequent Post-traumatic Stress Disorder and Mental Health Disorders among US Army Soldiers. ( 28895451 )
2017
44
A Pilot Study of the Effects of Mindfulness-Based Stress Reduction on Post-traumatic Stress Disorder Symptoms and Brain Response to Traumatic Reminders of Combat in Operation Enduring Freedom/Operation Iraqi Freedom Combat Veterans with Post-traumatic Stress Disorder. ( 28890702 )
2017
45
Post-traumatic stress disorder symptom duration and remission in relation to cardiovascular disease risk among a large cohort of women. ( 28052776 )
2017
46
Controlled Rhythmic Yogic Breathing as Complementary Treatment for Post-Traumatic Stress Disorder in Military Veterans: A Case Series. ( 28874925 )
2017
47
COMT Val(158)Met polymorphism is associated with post-traumatic stress disorder and functional outcome following mild traumatic brain injury. ( 27769642 )
2017
48
Symptom management in complex post-traumatic stress disorder (ICD-11), view and experience of patients and their relatives: a mixed methods approach (Research Proposal). ( 28882157 )
2017
49
Resveratrol ameliorated the behavioral deficits in a mouse model of post-traumatic stress disorder. ( 28947177 )
2017
50
Genetic variability of interleukin-1 beta as prospective factor from developing post-traumatic stress disorder. ( 28681202 )
2017

Variations for Post-Traumatic Stress Disorder

Expression for Post-Traumatic Stress Disorder

Search GEO for disease gene expression data for Post-Traumatic Stress Disorder.

Pathways for Post-Traumatic Stress Disorder

Pathways related to Post-Traumatic Stress Disorder according to GeneCards Suite gene sharing:

(show all 12)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.52 ADCYAP1R1 COMT DRD2 MAOA MAOB
2
Show member pathways
11.77 BDNF DRD2 MAOA MAOB
3 11.72 HTR2A MAOA MAOB SLC6A4
4
Show member pathways
11.53 COMT MAOA MAOB
5 11.44 ADCYAP1 ADCYAP1R1 BDNF HTR2A IL1B MAOA
6
Show member pathways
11.24 IL1B MAOA SLC6A4
7 10.94 HTR2A MAOA SLC6A4
8
Show member pathways
10.85 COMT MAOA SLC6A4
9
Show member pathways
10.62 MAOA MAOB
10
Show member pathways
10.54 ADCYAP1 ADCYAP1R1
11
Show member pathways
10.51 COMT MAOA MAOB
12 10.28 COMT MAOA MAOB

GO Terms for Post-Traumatic Stress Disorder

Biological processes related to Post-Traumatic Stress Disorder according to GeneCards Suite gene sharing:

(show all 22)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.89 ADCYAP1 CRH CRP IL1B SLC6A4
2 response to lipopolysaccharide GO:0032496 9.81 CNR1 COMT IL1B MAOB
3 response to toxic substance GO:0009636 9.78 DRD2 MAOB SLC6A4
4 female pregnancy GO:0007565 9.76 ADCYAP1 COMT CRH
5 memory GO:0007613 9.7 CNR1 HTR2A SLC6A4
6 sensory perception of pain GO:0019233 9.65 ADCYAP1 CNR1 HTR2A
7 positive regulation of cAMP biosynthetic process GO:0030819 9.63 ADCYAP1 ADCYAP1R1 CRH
8 response to corticosterone GO:0051412 9.6 CRH MAOB
9 negative regulation of synaptic transmission, glutamatergic GO:0051967 9.59 DRD2 HTR2A
10 dopamine metabolic process GO:0042417 9.58 COMT DRD2
11 response to cocaine GO:0042220 9.58 CNR1 CRH DRD2
12 regulation of synaptic transmission, GABAergic GO:0032228 9.57 CNR1 DRD2
13 negative regulation of potassium ion transport GO:0043267 9.56 ADCYAP1 HTR2A
14 catecholamine metabolic process GO:0006584 9.55 COMT MAOA
15 positive regulation of growth hormone secretion GO:0060124 9.54 ADCYAP1 DRD2
16 negative regulation of blood pressure GO:0045776 9.5 CNR1 CRH DRD2
17 response to drug GO:0042493 9.5 ADCYAP1R1 COMT CRH DRD2 HTR2A MAOB
18 positive regulation of fever generation GO:0031622 9.43 CNR1 IL1B
19 neurotransmitter catabolic process GO:0042135 9.43 COMT MAOA MAOB
20 negative regulation of dopamine secretion GO:0033602 9.37 CNR1 DRD2
21 dopamine catabolic process GO:0042420 9.33 COMT MAOA MAOB
22 response to ethanol GO:0045471 9.1 ADCYAP1 ADCYAP1R1 CNR1 CRH DRD2 MAOB

Molecular functions related to Post-Traumatic Stress Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 drug binding GO:0008144 9.13 CNR1 DRD2 HTR2A
2 primary amine oxidase activity GO:0008131 8.62 MAOA MAOB

Sources for Post-Traumatic Stress Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....