MCID: PST028
MIFTS: 55

Post-Traumatic Stress Disorder

Categories: Mental diseases, Neuronal diseases

Aliases & Classifications for Post-Traumatic Stress Disorder

MalaCards integrated aliases for Post-Traumatic Stress Disorder:

Name: Post-Traumatic Stress Disorder 12 29 41 14 69
Stress Disorders, Post-Traumatic 42
Traumatic Neurosis 12
Ptsd 45

Classifications:



External Ids:

Disease Ontology 12 DOID:2055
ICD10 33 F43.1 F43.10
ICD9CM 35 309.81
MeSH 42 D013313
NCIt 47 C3389
SNOMED-CT 64 192415000 47505003
UMLS 69 C0038436

Summaries for Post-Traumatic Stress Disorder

MedlinePlus : 41 post-traumatic stress disorder (ptsd) is a real illness. you can get ptsd after living through or seeing a traumatic event, such as war, a hurricane, sexual assault, physical abuse, or a bad accident. ptsd makes you feel stressed and afraid after the danger is over. it affects your life and the people around you. ptsd can cause problems like flashbacks, or feeling like the event is happening again trouble sleeping or nightmares feeling alone angry outbursts feeling worried, guilty, or sad ptsd starts at different times for different people. signs of ptsd may start soon after a frightening event and then continue. other people develop new or more severe signs months or even years later. ptsd can happen to anyone, even children. treatment may include talk therapy, medicines, or both. treatment might take 6 to 12 weeks. for some people, it takes longer. nih: national institute of mental health

MalaCards based summary : Post-Traumatic Stress Disorder, also known as stress disorders, post-traumatic, is related to heroin dependence and personality disorder, and has symptoms including nervousness An important gene associated with Post-Traumatic Stress Disorder is CRH (Corticotropin Releasing Hormone), and among its related pathways/superpathways are Circadian entrainment and Circadian rythm related genes. The drugs Diazepam and Tramadol have been mentioned in the context of this disorder. Affiliated tissues include brain, eye and heart, and related phenotypes are homeostasis/metabolism and behavior/neurological

Disease Ontology : 12 An anxiety disorder which results from a traumatic experience that results in psychological trauma.

Related Diseases for Post-Traumatic Stress Disorder

Diseases related to Post-Traumatic Stress Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 141)
id Related Disease Score Top Affiliating Genes
1 heroin dependence 29.7 BDNF CNR1 DRD2 MAOA SLC6A4
2 personality disorder 28.6 BDNF CNR1 COMT CRH DRD2 HTR2A
3 schizophrenia 28.2 BDNF CNR1 COMT DRD2 HTR2A MAOA
4 traumatic brain injury 11.4
5 anxiety disorder 11.4
6 acute cervicitis 10.7 CRH NR3C1
7 cold-induced sweating syndrome 2 10.6 CRH DRD2 NR3C1
8 intracranial cavernous angioma 10.6 DRD2 SLC6A4
9 chronic toxic polyneuropathy 10.6 CRP NR3C1
10 rhinoscleroma 10.5 COMT DRD2
11 simple chronic conjunctivitis 10.5 BDNF CNR1
12 splenic abscess 10.5 DRD2 HTR2A SLC6A4
13 hyperthyroxinemia 10.5 DRD2 HTR2A SLC6A4
14 pompholyx 10.4 DRD2 HTR2A SLC6A4
15 ornithosis 10.4 DRD2 MAOA SLC6A4
16 ring chromosome 14 syndrome 10.4 COMT MAOA
17 allergic hypersensitivity disease 10.4 CNR1 DRD2 HTR2A
18 vascular cancer 10.4 CNR1 DRD2 HTR2A
19 ulcerative colitis 10.4 BDNF COMT DRD2
20 brain meningioma 10.4 BDNF COMT DRD2
21 teebi kaurah syndrome 10.4 COMT DRD2 HTR2A
22 autoimmune inner ear disease 10.3 CNR1 FAAH
23 brain injury 10.3
24 acute stress disorder 10.3
25 osteogenesis imperfecta, type ix 10.3 BDNF COMT DRD2
26 neurogenic bladder 10.3 HTR2A MAOA SLC6A4
27 dementia - subcortical 10.3 CNR1 COMT
28 orbit lymphoma 10.3 CNR1 FAAH
29 laryngeal adductor paralysis 10.3 CRH FKBP5 HTR2A SLC6A4
30 uterus intravascular leiomyomatosis 10.3 COMT MAOA SLC6A4
31 renpenning syndrome 10.2 COMT MAOA SLC6A4
32 bladder flat intraepithelial lesion 10.2 BDNF DRD2 HTR2A SLC6A4
33 conjunctival degeneration 10.2 HTR2A SLC6A4
34 c8 deficiency, type ii 10.1 COMT DRD2 FAAH
35 amyloidosis, finnish type 10.1 COMT MAOA MAOB
36 conjunctival pigmentation 10.1 CRH MAOA MAOB SLC6A4
37 hemorrhagic cystitis 10.1 COMT DRD2 MAOA SLC6A4
38 pervasive developmental disorder 10.1 BDNF CNR1 COMT SLC6A4
39 hallucinogen dependence 10.1 BDNF CNR1 CRH DRD2 SLC6A4
40 breast cancer 10.1
41 alcohol dependence 10.1
42 primary angle-closure glaucoma 10.1 BDNF COMT HTR2A SLC6A4
43 carotid stenosis 10.1 COMT DRD2 MAOA SLC6A4
44 giant cell reparative granuloma 10.0 CNR1 COMT FAAH
45 borderline personality disorder 10.0
46 cerebritis 10.0
47 parkinsonism-dystonia, infantile 10.0 COMT DRD2 HTR2A MAOA
48 anosognosia 10.0 COMT CRP DRD2 SLC6A4
49 panic disorder 10.0
50 chronic pain 10.0

Comorbidity relations with Post-Traumatic Stress Disorder via Phenotypic Disease Network (PDN):


Anxiety Disorder Dysthymic Disorder

Graphical network of the top 20 diseases related to Post-Traumatic Stress Disorder:



Diseases related to Post-Traumatic Stress Disorder

Symptoms & Phenotypes for Post-Traumatic Stress Disorder

UMLS symptoms related to Post-Traumatic Stress Disorder:


nervousness

MGI Mouse Phenotypes related to Post-Traumatic Stress Disorder:

44 (show all 13)
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.45 ADCYAP1 ADCYAP1R1 BDNF CNR1 COMT CRH
2 behavior/neurological MP:0005386 10.41 ADCYAP1R1 BDNF CNR1 COMT CRH DRD2
3 mortality/aging MP:0010768 10.25 ADCYAP1 ADCYAP1R1 BDNF CNR1 DRD2 FAAH
4 nervous system MP:0003631 10.24 SLC6A4 ADCYAP1 ADCYAP1R1 BDNF CNR1 COMT
5 immune system MP:0005387 10.22 RORA SKA2 ADCYAP1 ADCYAP1R1 COMT CRH
6 integument MP:0010771 10.11 BDNF CNR1 CRH DRD2 FAAH IL1B
7 adipose tissue MP:0005375 10 ADCYAP1 CNR1 CRH DRD2 NR3C1 PREP
8 muscle MP:0005369 9.95 NR3C1 RORA SLC6A4 ADCYAP1 DRD2 FAAH
9 no phenotypic analysis MP:0003012 9.92 ADCYAP1 ADCYAP1R1 BDNF CNR1 CRH DRD2
10 normal MP:0002873 9.91 FKBP5 NR3C1 SLC6A4 ADCYAP1R1 BDNF CNR1
11 renal/urinary system MP:0005367 9.7 COMT CRH DRD2 FKBP5 MAOB NR3C1
12 reproductive system MP:0005389 9.61 ADCYAP1 ADCYAP1R1 BDNF CNR1 COMT DRD2
13 taste/olfaction MP:0005394 8.92 BDNF CNR1 DRD2 RORA

Drugs & Therapeutics for Post-Traumatic Stress Disorder

Drugs for Post-Traumatic Stress Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 350)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Diazepam Approved, Illicit, Vet_approved Phase 4 439-14-5 3016
2
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
3
Dronabinol Approved, Illicit Phase 4,Phase 2,Phase 1 1972-08-3 16078 2978
4
Fluoxetine Approved, Vet_approved Phase 4,Phase 3,Phase 1 54910-89-3 3386
5
Propranolol Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 525-66-6 4946
6
Sertraline Approved Phase 4,Phase 3,Phase 2,Phase 1 79617-96-2 68617
7
Ethanol Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 64-17-5 702
8
Paroxetine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 61869-08-7 43815
9
Topiramate Approved Phase 4,Phase 2,Phase 3 97240-79-4 5284627
10
Cycloserine Approved Phase 4,Phase 2,Phase 3 68-41-7 401 6234
11
Mifepristone Approved, Investigational Phase 4,Phase 2,Phase 1 84371-65-3 55245
12
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 51-61-6, 62-31-7 681
13
Benzocaine Approved Phase 4,Phase 3 1994-09-7, 94-09-7 2337
14
Oxytocin Approved, Vet_approved Phase 4,Phase 2,Phase 1,Early Phase 1 50-56-6 439302 53477758
15
Citalopram Approved Phase 4,Phase 3,Phase 2 59729-33-8 2771
16
Hydrocortisone Approved, Vet_approved Phase 4,Phase 2,Phase 3 50-23-7 5754 657311
17
Norepinephrine Approved Phase 4,Phase 3,Phase 1,Early Phase 1 51-41-2 439260
18
Prazosin Approved Phase 4,Phase 3,Phase 2,Phase 1 19216-56-9 4893
19
Lorazepam Approved Phase 4 846-49-1 3958
20
Midazolam Approved, Illicit Phase 4,Phase 3,Phase 2 59467-70-8 4192
21
Ketamine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 6740-88-1 3821
22
Naltrexone Approved, Investigational, Vet_approved Phase 4,Phase 2 16590-41-3 5360515
23
Asenapine Approved Phase 4 85650-56-2, 65576-45-6 3001386
24
Clonazepam Approved, Illicit Phase 4 1622-61-3 2802
25
Eszopiclone Approved Phase 4 138729-47-2 969472
26
Ziprasidone Approved Phase 4,Phase 3,Phase 2 146939-27-7 60854
27
Histamine Approved, Investigational Phase 4 75614-87-8, 51-45-6 774
28
Mianserin Approved Phase 4 24219-97-4 4184
29
Mirtazapine Approved Phase 4 85650-52-8, 61337-67-5 4205
30
Memantine Approved, Investigational Phase 4 19982-08-2 4054
31
Risperidone Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 106266-06-2 5073
32
Haloperidol Approved Phase 4,Phase 3 52-86-8 3559
33
Doxazosin Approved Phase 4,Phase 2,Phase 1 74191-85-8 3157
34
Carbon monoxide Approved Phase 4 630-08-0 281
35
Guanfacine Approved, Investigational Phase 4,Phase 1 29110-47-2 3519
36
Valproic Acid Approved, Investigational Phase 4,Phase 3 99-66-1 3121
37
Vortioxetine Approved Phase 4 508233-74-7 9966051
38
Suvorexant Approved Phase 4 1030377-33-3
39
Levodopa Approved Phase 4 59-92-7 6047
40
Lormetazepam Approved Phase 4 848-75-9 13314
41 tannic acid Approved, Nutraceutical Phase 4,Phase 3
42
Melatonin Approved, Nutraceutical, Vet_approved Phase 4 73-31-4 896
43
Caffeine Approved, Nutraceutical Phase 4 58-08-2 2519
44
Butyric Acid Experimental Phase 4,Phase 3,Phase 2 107-92-6 264
45 Adjuvants, Anesthesia Phase 4,Phase 3,Phase 2,Phase 1
46 Anesthetics Phase 4,Phase 3,Phase 2,Phase 1
47 Anesthetics, General Phase 4,Phase 3,Phase 2,Phase 1
48 Anesthetics, Intravenous Phase 4,Phase 3,Phase 2,Phase 1
49 Anti-Anxiety Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
50 Anticonvulsants Phase 4,Phase 2,Phase 3,Phase 1

Interventional clinical trials:

(show top 50) (show all 1224)

id Name Status NCT ID Phase Drugs
1 Transcranial Magnetic Stimulation for Post-Traumatic Stress Disorder Unknown status NCT00134446 Phase 4
2 Prevention of Posttraumatic Stress Disorder (PTSD) With Diazepam Unknown status NCT01221883 Phase 4 Diazepam
3 Tramadol Extended-Release (ER) for Posttraumatic Stress Disorder (PTSD) Unknown status NCT01517711 Phase 4 Tramadol;Placebo
4 Add on Study on Δ9-THC Treatment for Posttraumatic Stress Disorders (PTSD) Unknown status NCT00965809 Phase 4 Tetrahydrocannabinol
5 Predictors of Treatment Response to Fluoxetine in PTSD Following a Recent History of War Zone Stress Exposure Unknown status NCT00633685 Phase 4 Fluoxetine;Placebo
6 A Randomized Cross Over Trial of Two Treatments for Obstructive Sleep Apnea in Veterans With Post Traumatic Stress Disorder Unknown status NCT01535586 Phase 4
7 Effect of Propranolol on Preventing Posttraumatic Stress Disorder Completed NCT00158262 Phase 4 Propranolol;Placebo
8 PROlonGed ExpoSure Sertraline Completed NCT01524133 Phase 4 Sertraline
9 Treatment for Alcoholism and Post-Traumatic Stress Disorder (Naltrexone) Completed NCT00006489 Phase 4 Naltrexone;Placebo
10 An Open Label Pilot Study of Adjunctive Asenapine for the Treatment of Posttraumatic Stress Disorder Completed NCT01587118 Phase 4 Adjunctive asenapine
11 Cognitive Behavioral Therapy Versus Sertraline in the Treatment of Post-Traumatic Stress Disorder Completed NCT00391430 Phase 4 Sertraline
12 Clonazepam and Paroxetine for Rapid Treatment of Post-Traumatic Stress Disorder Completed NCT00025740 Phase 4 clonazepam and paroxetine
13 Eszopiclone for Sleep Disturbance and Nightmares in Post-Traumatic Stress Disorder Completed NCT00120250 Phase 4 Eszopiclone
14 Placebo Controled Clinical Trial Using Topiramate To Treat Posttraumatic Stress Disorder (PTSD) Patients. Completed NCT00725920 Phase 4 Topiramate;placebo control group
15 Eszopiclone for the Treatment of Posttraumatic Stress Disorder Completed NCT01605253 Phase 4 Eszopiclone;Placebo
16 Developing Memory Reconsolidation Blockers as Novel Posttraumatic Stress Disorder (PTSD) Treatments Completed NCT01490697 Phase 4 Mifepristone;d-Cycloserine;Placebo-matching Mifepristone;Placebo-matching d-Cycloserine (DCS)
17 Geodon (Ziprasidone) for Posttraumatic Stress Disorder Completed NCT00208208 Phase 4 Ziprasidone
18 Topiramate in the Treatment of Posttraumatic Stress Disorder in Civilians Completed NCT00208130 Phase 4 Topiramate
19 Brain Markers of Treatment Response in Post-Traumatic Stress Disorder (PTSD) Completed NCT00700999 Phase 4 Paroxetine
20 Secondary Prevention With Paroxetine vs. Placebo in Subthreshold Posttraumatic Stress Disorder (PTSD) Completed NCT00560612 Phase 4 Paroxetine;Placebo
21 Vilazodone for the Treatment of Posttraumatic Stress Disorder Completed NCT01715519 Phase 4 Treatment (Viibryd)
22 Topiramate Treatment of Alcohol Use Disorders in Veterans With Post Traumatic Stress Disorder (PTSD): A Pilot Controlled Trial of Augmentation Therapy Completed NCT01087736 Phase 4 Topiramate
23 Neural Circuits in Women With Abuse and Posttraumatic Stress Disorder Completed NCT01681849 Phase 4 Placebo;Paroxetine
24 Combined Mirtazapine and SSRI Treatment of PTSD: A Placebo-Controlled Trial Completed NCT01178671 Phase 4 Mirtazapine;Sertraline
25 Effects of Paxil CR on Neural Circuits in Posttraumatic Stress Disorder (PTSD) Completed NCT00672776 Phase 4 paroxetine;placebo
26 Topiramate in the Treatment of Post Traumatic Stress Disorder (PTSD) Completed NCT00203463 Phase 4 topiramate
27 A Psychophysiologic Study of Weakening Traumatic Combat Memories With Post-Reactivation Propranolol Completed NCT00709735 Phase 4 Propranolol;Placebo
28 Combination Treatment for Posttraumatic Stress Disorder (PTSD) After the World Trade Center (WTC) Attack Completed NCT01130103 Phase 4 Paroxetine
29 The Effect of Intranasal Oxytocin on Emphatic Abilities in Patients With Post Traumatic Stress Disorder (PTSD) Completed NCT01325168 Phase 4 syntocinon nasal spray;placebo nasal spray
30 Effects of Escitalopram on Autonomic Reactivity in Post Traumatic Stress Disorder Completed NCT01271244 Phase 4 Escitalopram
31 An Open-Label Trial of Memantine for Cognitive Impairment in Patients With Post-Traumatic Stress Disorder Completed NCT02258828 Phase 4 Memantine
32 Telemedicine Outreach for Post Traumatic Stress in CBOCs Completed NCT00821678 Phase 4
33 Veteran Stress and Learning Study Completed NCT00674570 Phase 4 Hydrocortisone;D-Cycloserine;Placebo
34 Risperidone in the Treatment of PTSD in Women Survivors of Domestic Abuse and Rape Trauma Completed NCT00208182 Phase 4 Risperidone
35 The Outcome of Treatment of Traumatised Refugees With Psychotherapy and/or Antidepressants Completed NCT00917397 Phase 4 Sertraline
36 A Study of Sertraline to Prevent PTSD Completed NCT00182078 Phase 4 Placebo;Sertraline
37 Quetiapine Treatment for Post-Traumatic Stress Disorder (PTSD) Completed NCT00237393 Phase 4 Quetiapine;Placebo
38 Evaluation of Stress Disorders Completed NCT00050804 Phase 4 sertraline
39 The Treatment of Traumatised Refugees With Sertraline Versus Venlafaxine in Combination With Psychotherapy Completed NCT01569685 Phase 4 Venlafaxine;Sertraline
40 Prazosin Treatment for Combat Trauma PTSD (Post-Traumatic Stress Disorder) Nightmares and Sleep Disturbance Completed NCT00108420 Phase 4 Prazosin
41 Veterans Individual Placement and Support Towards Advancing Recovery Completed NCT01817712 Phase 4
42 Posttraumatic Symptoms Among Toddlers and Their Parents Following Exposure to Terrorism Completed NCT00447538 Phase 4
43 Primary Care Intervention Strategy for Anxiety Disorders Completed NCT00347269 Phase 4 Psychotropic medication optimization
44 Serotonin Selective Reuptake Inhibitor Treatment of Dual Diagnosis Post-traumatic Stress Disorder and Alcohol Problems Completed NCT02504931 Phase 4 Sertraline;Placebo
45 Pilot Study of Pharmaceutical and Behavioral Interventions to Treat Anxiety Disorders Completed NCT01631682 Phase 4 Propranolol;Mifepristone;Intranasal oxytocin
46 Influence of Hydrocortisone on Immunologic Markers and Health Care Related Quality of Life in Patients After Cardiac Surgery Completed NCT00490828 Phase 4 Hydrocortisone
47 A Placebo-Controlled Study of Mirtazapine for PTSD Completed NCT00302107 Phase 4 Mirtazapine;Placebo
48 Cardiopulmonary Resuscitation Witnessing by a Relative Completed NCT01009606 Phase 4
49 Prazosin Alcohol Dependence IVR Study Completed NCT00167687 Phase 4 prazosin
50 Oral Melatonin in Critically Ill High-risk Patients Completed NCT00470821 Phase 4 Oral melatonin 3mg BID;Placebo

Search NIH Clinical Center for Post-Traumatic Stress Disorder

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: stress disorders, post-traumatic

Genetic Tests for Post-Traumatic Stress Disorder

Genetic tests related to Post-Traumatic Stress Disorder:

id Genetic test Affiliating Genes
1 Post-Traumatic Stress Disorder 29

Anatomical Context for Post-Traumatic Stress Disorder

MalaCards organs/tissues related to Post-Traumatic Stress Disorder:

39
Brain, Eye, Heart, Testes, Cortex, Lung, Prefrontal Cortex

Publications for Post-Traumatic Stress Disorder

Articles related to Post-Traumatic Stress Disorder:

(show top 50) (show all 701)
id Title Authors Year
1
Prolonged exposure therapy for the treatment of patients diagnosed with psychogenic non-epileptic seizures (PNES) and post-traumatic stress disorder (PTSD). ( 28038392 )
2017
2
Effect of oleuropein on cognitive deficits and changes in hippocampal brain-derived neurotrophic factor and cytokine expression in a rat model of post-traumatic stress disorder. ( 28884427 )
2017
3
Trauma exposure and post-traumatic stress disorder in a cohort of pregnant Peruvian women. ( 28905129 )
2017
4
Comorbidity of post-traumatic stress disorder and anxiety in flood survivors: Prevalence and shared risk factors. ( 28885358 )
2017
5
COMT Val(158)Met polymorphism is associated with post-traumatic stress disorder and functional outcome following mild traumatic brain injury. ( 27769642 )
2017
6
Controlled Rhythmic Yogic Breathing as Complementary Treatment for Post-Traumatic Stress Disorder in Military Veterans: A Case Series. ( 28874925 )
2017
7
Six Sessions of Emotional Freedom Techniques Remediate One Veteran's Combat-Related Post-Traumatic Stress Disorder. ( 28874927 )
2017
8
A case of enterobiasis presenting as post-traumatic-stress-disorder (PTSD): a curious case of the infection with predominant mental health symptoms, presenting for the first time in the settings of a refugee camp. ( 28819532 )
2017
9
Risk of relapse after antidepressant discontinuation in anxiety disorders, obsessive-compulsive disorder, and post-traumatic stress disorder: systematic review and meta-analysis of relapse prevention trials. ( 28947609 )
2017
10
Risk Factors for Mild Traumatic Brain Injury and Subsequent Post-traumatic Stress Disorder and Mental Health Disorders among US Army Soldiers. ( 28895451 )
2017
11
Alpha-1 Acid Glycoprotein (orosomucoid): An Overlooked Piece of Post Traumatic Stress Disorder Pathology? ( 28915958 )
2017
12
The effect of Elettaria cardamomum extract on anxiety-like behavior in a rat model of post-traumatic stress disorder. ( 28073098 )
2017
13
Post-traumatic stress disorder symptom duration and remission in relation to cardiovascular disease risk among a large cohort of women. ( 28052776 )
2017
14
A Pilot Study of the Effects of Mindfulness-Based Stress Reduction on Post-traumatic Stress Disorder Symptoms and Brain Response to Traumatic Reminders of Combat in Operation Enduring Freedom/Operation Iraqi Freedom Combat Veterans with Post-traumatic Stress Disorder. ( 28890702 )
2017
15
Secondary psychotic features in refugees diagnosed with post-traumatic stress disorder: a retrospective cohort study. ( 28056884 )
2017
16
Disrupted cortical brain network in post-traumatic stress disorder patients: a resting-state electroencephalographic study. ( 28895942 )
2017
17
Self-esteem and hope mediate the relations between social support and post-traumatic stress disorder and growth in adolescents following the Ya'an earthquake. ( 28882068 )
2017
18
Dissociation between amygdala and bed nucleus of the stria terminalis during threat anticipation in female post-traumatic stress disorder patients. ( 28070973 )
2017
19
Risk of relapse after antidepressant discontinuation in anxiety disorders, obsessive-compulsive disorder, and post-traumatic stress disorder: systematic review and meta-analysis of relapse prevention trials. ( 28903922 )
2017
20
Resveratrol ameliorated the behavioral deficits in a mouse model of post-traumatic stress disorder. ( 28947177 )
2017
21
Childhood adversities and post-traumatic stress disorder: evidence for stress sensitisation in the World Mental Health Surveys. ( 28935660 )
2017
22
Impaired working memory updating affects memory for emotional and non-emotional materials the same way: evidence from post-traumatic stress disorder (PTSD). ( 28929242 )
2017
23
Dissociation between working memory performance and proactive interference control in post-traumatic stress disorder. ( 28077328 )
2017
24
Mind-Body Therapy for Military Veterans with Post-Traumatic Stress Disorder: A Systematic Review. ( 28880607 )
2017
25
Symptom management in complex post-traumatic stress disorder (ICD-11), view and experience of patients and their relatives: a mixed methods approach (Research Proposal). ( 28882157 )
2017
26
A Study of Selected Ethnic Affiliations in the Development of Post-traumatic Stress Disorder and Other Psychopathology After a Terrorist Bombing in Nairobi, Kenya. ( 28925342 )
2017
27
Depression and post-traumatic stress disorder in individuals with hereditary hemorrhagic telangiectasia: A cross-sectional survey. ( 28314138 )
2017
28
Post-traumatic Stress Disorder and Complicated Grief are Common in Caregivers of Neuro-ICU Patients. ( 28054288 )
2017
29
Effects of vagus nerve stimulation on extinction of conditioned fear and post-traumatic stress disorder symptoms in rats. ( 28892066 )
2017
30
Exploring a post-traumatic stress disorder paradigm in Flinders sensitive line rats to model treatment-resistant depression I: bio-behavioural validation and response to imipramine. ( 27573792 )
2016
31
Intervention Efficacy in Engaging Black and White Veterans with Post-traumatic Stress Disorder into Treatment. ( 27210830 )
2016
32
Post-War Research on Post-Traumatic Stress Disorder. Part II - 1989 onwards. ( 27992888 )
2016
33
Charles Darwin's (1809-1882) illness - the role of post-traumatic stress disorder. ( 27635031 )
2016
34
Exercise and Post-Traumatic Stress Disorder in Military Veterans: A Systematic Review. ( 27612337 )
2016
35
A pilot study of the trauma recovery group for veterans with post traumatic stress disorder and co-occurring serious mental illness. ( 27649807 )
2016
36
Breaking down the silos of treatment for post-traumatic stress disorder: integrating mind and body. ( 27169961 )
2016
37
Toward Preventing Post-Traumatic Stress Disorder: Development and Testing of a Pilot Predeployment Stress Inoculation Training Program. ( 27612367 )
2016
38
Genome-wide gene-based analysis suggests an association between Neuroligin 1 (NLGN1) and post-traumatic stress disorder. ( 27219346 )
2016
39
The Anti-Inflammatory Effects of Blueberries in an Animal Model of Post-Traumatic Stress Disorder (PTSD). ( 27603014 )
2016
40
Management of breast cancer in an Asian man with post-traumatic stress disorder: a case report. ( 27113572 )
2016
41
Emergence Delirium With Post-traumatic Stress Disorder Among Military Veterans. ( 28083465 )
2016
42
Exploring the impact of parental post-traumatic stress disorder on military family children: A review of the literature. ( 27189880 )
2016
43
Evidence for the changes of pituitary volumes in patients with post-traumatic stress disorder. ( 28013068 )
2016
44
Post-traumatic Stress Disorder Symptoms Among People Living with HIV/AIDS in Rural China. ( 27990584 )
2016
45
'Everything just seems much more right in nature': How veterans with post-traumatic stress disorder experience nature-based activities in a forest therapy garden. ( 28070397 )
2016
46
Post-traumatic Stress Disorder Symptoms and Mental Health over Time among Low-Income Women at Increased Risk of HIV in the U.S. ( 27180715 )
2016
47
Nature and Treatment of Comorbid Alcohol Problems and Post Traumatic Stress Disorder Among American Military Personnel and Veterans. ( 27159820 )
2016
48
Intergenerational transmission of post-traumatic stress disorder in Australian Vietnam veterans' families. ( 28032331 )
2016
49
Serum brain-derived neurotrophic factor (BDNF) concentrations in pregnant women with post-traumatic stress disorder and comorbid depression. ( 27193345 )
2016
50
Treating Post-traumatic Stress Disorder in Patients with Multiple Sclerosis: A Randomized Controlled Trial Comparing the Efficacy of Eye Movement Desensitization and Reprocessing and Relaxation Therapy. ( 27148134 )
2016

Variations for Post-Traumatic Stress Disorder

Expression for Post-Traumatic Stress Disorder

Search GEO for disease gene expression data for Post-Traumatic Stress Disorder.

Pathways for Post-Traumatic Stress Disorder

Pathways related to Post-Traumatic Stress Disorder according to GeneCards Suite gene sharing:

(show all 14)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.54 ADCYAP1R1 COMT DRD2 MAOA MAOB
3 11.77 IL1B MAOA RORA
4
Show member pathways
11.77 BDNF DRD2 MAOA MAOB
5 11.72 HTR2A MAOA MAOB SLC6A4
6
Show member pathways
11.55 COMT MAOA MAOB
7 11.49 ADCYAP1 ADCYAP1R1 BDNF HTR2A IL1B MAOA
8
Show member pathways
11.24 IL1B MAOA SLC6A4
9 10.94 HTR2A MAOA SLC6A4
10
Show member pathways
10.86 COMT MAOA SLC6A4
11
Show member pathways
10.64 MAOA MAOB
12
Show member pathways
10.55 ADCYAP1 ADCYAP1R1
13 10.48 COMT MAOA MAOB
14
Show member pathways
10.28 COMT MAOA MAOB

GO Terms for Post-Traumatic Stress Disorder

Cellular components related to Post-Traumatic Stress Disorder according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 axon GO:0030424 8.92 CNR1 COMT DRD2 HTR2A

Biological processes related to Post-Traumatic Stress Disorder according to GeneCards Suite gene sharing:

(show all 23)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.88 ADCYAP1 CRH CRP IL1B SLC6A4
2 response to lipopolysaccharide GO:0032496 9.81 CNR1 COMT IL1B MAOB
3 response to toxic substance GO:0009636 9.78 DRD2 MAOB SLC6A4
4 female pregnancy GO:0007565 9.76 ADCYAP1 COMT CRH
5 memory GO:0007613 9.7 CNR1 HTR2A SLC6A4
6 sensory perception of pain GO:0019233 9.67 ADCYAP1 CNR1 HTR2A
7 synaptic transmission, dopaminergic GO:0001963 9.61 CRH DRD2
8 positive regulation of cAMP biosynthetic process GO:0030819 9.61 ADCYAP1 ADCYAP1R1 CRH
9 response to corticosterone GO:0051412 9.6 CRH MAOB
10 negative regulation of synaptic transmission, glutamatergic GO:0051967 9.59 DRD2 HTR2A
11 dopamine metabolic process GO:0042417 9.58 COMT DRD2
12 response to cocaine GO:0042220 9.58 CNR1 CRH DRD2
13 regulation of synaptic transmission, GABAergic GO:0032228 9.57 CNR1 DRD2
14 negative regulation of potassium ion transport GO:0043267 9.56 ADCYAP1 HTR2A
15 catecholamine metabolic process GO:0006584 9.55 COMT MAOA
16 positive regulation of growth hormone secretion GO:0060124 9.54 ADCYAP1 DRD2
17 negative regulation of blood pressure GO:0045776 9.5 CNR1 CRH DRD2
18 response to drug GO:0042493 9.5 ADCYAP1R1 COMT CRH DRD2 HTR2A MAOB
19 positive regulation of fever generation GO:0031622 9.46 CNR1 IL1B
20 neurotransmitter catabolic process GO:0042135 9.43 COMT MAOA MAOB
21 negative regulation of dopamine secretion GO:0033602 9.37 CNR1 DRD2
22 dopamine catabolic process GO:0042420 9.33 COMT MAOA MAOB
23 response to ethanol GO:0045471 9.1 ADCYAP1 ADCYAP1R1 CNR1 CRH DRD2 MAOB

Molecular functions related to Post-Traumatic Stress Disorder according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 drug binding GO:0008144 9.13 CNR1 DRD2 HTR2A
2 primary amine oxidase activity GO:0008131 8.62 MAOA MAOB

Sources for Post-Traumatic Stress Disorder

3 CDC
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