PTSD
MCID: PST028
MIFTS: 57

Post-Traumatic Stress Disorder (PTSD) malady

Categories: Mental diseases, Neuronal diseases

Aliases & Classifications for Post-Traumatic Stress Disorder

Aliases & Descriptions for Post-Traumatic Stress Disorder:

Name: Post-Traumatic Stress Disorder 12 29 41 14 69
Stress Disorders, Post-Traumatic 42
Posttraumatic Stress Disorder 14
Traumatic Neurosis 12
Ptsd 45

Classifications:



External Ids:

Disease Ontology 12 DOID:2055
ICD10 33 F43.1 F43.10
ICD9CM 35 309.81
MeSH 42 D013313
NCIt 47 C3389
SNOMED-CT 64 192415000 47505003
UMLS 69 C0038436

Summaries for Post-Traumatic Stress Disorder

MedlinePlus : 41 post-traumatic stress disorder (ptsd) is a real illness. you can get ptsd after living through or seeing a traumatic event, such as war, a hurricane, sexual assault, physical abuse, or a bad accident. ptsd makes you feel stressed and afraid after the danger is over. it affects your life and the people around you. ptsd can cause problems like flashbacks, or feeling like the event is happening again trouble sleeping or nightmares feeling alone angry outbursts feeling worried, guilty, or sad ptsd starts at different times for different people. signs of ptsd may start soon after a frightening event and then continue. other people develop new or more severe signs months or even years later. ptsd can happen to anyone, even children. treatment may include talk therapy, medicines, or both. treatment might take 6 to 12 weeks. for some people, it takes longer. nih: national institute of mental health

MalaCards based summary : Post-Traumatic Stress Disorder, also known as stress disorders, post-traumatic, is related to schizophrenia and personality disorder, and has symptoms including nervousness An important gene associated with Post-Traumatic Stress Disorder is CRH (Corticotropin Releasing Hormone), and among its related pathways/superpathways are Peptide ligand-binding receptors and G-Beta Gamma Signaling. The drugs Diazepam and Tramadol have been mentioned in the context of this disorder. Affiliated tissues include brain, cortex and heart, and related phenotypes are behavior/neurological and homeostasis/metabolism

Disease Ontology : 12 An anxiety disorder which results from a traumatic experience that results in psychological trauma.

Wikipedia : 71 Posttraumatic stress disorder (PTSD)[note 1] is a mental disorder that can develop after a person is... more...

Related Diseases for Post-Traumatic Stress Disorder

Diseases related to Post-Traumatic Stress Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 130)
id Related Disease Score Top Affiliating Genes
1 schizophrenia 29.3 BDNF CNR1 COMT DRD2 HTR2A MAOA
2 personality disorder 29.1 BDNF CNR1 COMT CRH DRD2 HTR2A
3 traumatic brain injury 11.4
4 anxiety disorder 11.4
5 dissociative seizures 10.9
6 persian gulf syndrome 10.9
7 acute stress disorder 10.3
8 brain injury 10.3
9 teratoma with malignant transformation 10.2 BDNF DRD2 HTR2A
10 apperceptive agnosia 10.2 COMT DRD2 SLC6A4
11 conjunctival pigmentation 10.2 CRH MAOA SLC6A4
12 splenic abscess 10.2 DRD2 HTR2A SLC6A4
13 euthyroid sick syndrome 10.2 DRD2 HTR2A SLC6A4
14 nephronophthisis 13 10.2 COMT HTR2A SLC6A4
15 ornithosis 10.2 DRD2 MAOA SLC6A4
16 waardenburg's syndrome 10.1 DRD2 HTR2A SLC6A4
17 renpenning syndrome 10.1 COMT MAOA SLC6A4
18 allergic hypersensitivity disease 10.1 CNR1 DRD2 HTR2A
19 vascular cancer 10.1 CNR1 DRD2 HTR2A
20 alzheimer disease 17 10.1 CRH FKBP5 HTR2A SLC6A4
21 alopecia 10.1 BDNF CNR1 DRD2 SLC6A4
22 neurogenic bladder 10.1 HTR2A MAOA SLC6A4
23 breast cancer 10.1
24 alcohol dependence 10.1
25 colorectal adenocarcinoma 10.1 COMT DRD2 MAOA SLC6A4
26 strongyloidiasis 10.1 COMT DRD2 MAOA SLC6A4
27 deafness, autosomal recessive 20 10.1 CRH CRHR1 SLC6A4
28 primary angle-closure glaucoma 10.1 BDNF COMT HTR2A SLC6A4
29 urea cycle disorder 10.1 BDNF COMT DRD2 IL1B
30 breast reconstruction 10.1 BDNF COMT DRD2 IL1B
31 pyromania 10.1 DRD2 HTR2A MAOA SLC6A4
32 hemochromatosis, type 2a 10.0 BDNF COMT DRD2 MAOA
33 basal cell carcinoma 3 10.0 COMT DRD2 HTR2A MAOA
34 cerebritis 10.0
35 borderline personality disorder 10.0
36 nonparalytic poliomyelitis 10.0 CRH NR3C1 POMC
37 tuberculous peritonitis 10.0 CRH CRHR1 SLC6A4
38 kashin-beck disease 10.0 BDNF CNR1 NPY
39 hepatitis b reinfection following liver transplantation 10.0 HTR2A MAOA SLC6A4
40 chronic eosinophilic pneumonia 10.0 BDNF COMT CRH MAOA SLC6A4
41 brain glioblastoma multiforme 10.0 BDNF COMT DRD2 HTR2A SLC6A4
42 merkel cell carcinoma 10.0 CRH NR3C1 POMC
43 cocaine dependence 10.0
44 alexithymia 10.0
45 panic disorder 10.0
46 chronic pain 10.0
47 neuronitis 10.0
48 infections, recurrent, with encephalopathy, hepatic dysfunction, and cardiovasuclar malformations 10.0 CRH DRD2 NR3C1 POMC
49 esophagus squamous cell papilloma 10.0 CRH NR3C1 POMC
50 cecal benign neoplasm 10.0 COMT DRD2 HTR2A MAOA SLC6A4

Comorbidity relations with Post-Traumatic Stress Disorder via Phenotypic Disease Network (PDN):


Anxiety Disorder Dysthymic Disorder

Graphical network of the top 20 diseases related to Post-Traumatic Stress Disorder:



Diseases related to Post-Traumatic Stress Disorder

Symptoms & Phenotypes for Post-Traumatic Stress Disorder

UMLS symptoms related to Post-Traumatic Stress Disorder:


nervousness

MGI Mouse Phenotypes related to Post-Traumatic Stress Disorder:

44 (show all 18)
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.5 COMT CRH CRHR1 DRD2 FKBP5 HTR2A
2 homeostasis/metabolism MP:0005376 10.46 RORA SKA2 SLC6A4 ADCYAP1 ADCYAP1R1 BDNF
3 growth/size/body region MP:0005378 10.31 ADCYAP1 ADCYAP1R1 BDNF CNR1 CRH DRD2
4 nervous system MP:0003631 10.31 ADCYAP1 ADCYAP1R1 BDNF CNR1 COMT CRH
5 mortality/aging MP:0010768 10.28 PREP RORA SKA2 SLC6A4 ADCYAP1 ADCYAP1R1
6 endocrine/exocrine gland MP:0005379 10.25 BDNF COMT CRH CRHR1 DRD2 HTR2A
7 immune system MP:0005387 10.24 ADCYAP1 ADCYAP1R1 COMT CRH DRD2 IL1B
8 hematopoietic system MP:0005397 10.22 DRD2 IL1B NR3C1 POMC PREP RORA
9 cardiovascular system MP:0005385 10.21 COMT CRHR1 DRD2 IL1B MAOA NR3C1
10 adipose tissue MP:0005375 10.18 ADCYAP1 CNR1 CRH DRD2 NPY NR3C1
11 integument MP:0010771 10.13 POMC RORA SLC6A4 CNR1 CRH DRD2
12 no phenotypic analysis MP:0003012 10.07 ADCYAP1 ADCYAP1R1 BDNF CNR1 CRH RORA
13 normal MP:0002873 10.02 ADCYAP1R1 BDNF CNR1 CRH CRHR1 DRD2
14 liver/biliary system MP:0005370 10 ADCYAP1 CRH DRD2 NPY NR3C1 POMC
15 renal/urinary system MP:0005367 9.86 COMT CRH DRD2 FKBP5 NPY NR3C1
16 reproductive system MP:0005389 9.81 ADCYAP1 ADCYAP1R1 BDNF CNR1 COMT DRD2
17 respiratory system MP:0005388 9.5 BDNF COMT CRH CRHR1 DRD2 NR3C1
18 taste/olfaction MP:0005394 8.92 DRD2 RORA BDNF CNR1

Drugs & Therapeutics for Post-Traumatic Stress Disorder

Drugs for Post-Traumatic Stress Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 350)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Diazepam Approved, Illicit, Vet_approved Phase 4 439-14-5 3016
2
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
3
Dronabinol Approved, Illicit Phase 4,Phase 2 1972-08-3 16078 2978
4
Fluoxetine Approved, Vet_approved Phase 4,Phase 3,Phase 1 54910-89-3 3386
5
Amantadine Approved Phase 4 768-94-5 2130
6
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 51-61-6, 62-31-7 681
7
Propranolol Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 525-66-6 4946
8
Paroxetine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 61869-08-7 43815
9
Ethanol Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 64-17-5 702
10
Sertraline Approved Phase 4,Phase 3,Phase 2,Phase 1 79617-96-2 68617
11
Topiramate Approved Phase 4,Phase 2,Phase 3 97240-79-4 5284627
12
Prazosin Approved Phase 4,Phase 3,Phase 2,Phase 1 19216-56-9 4893
13
Benzocaine Approved Phase 4,Phase 3 1994-09-7, 94-09-7 2337
14
Cycloserine Approved Phase 4,Phase 2,Phase 3 68-41-7 401 6234
15
Mifepristone Approved, Investigational Phase 4,Phase 2,Phase 1 84371-65-3 55245
16
Oxytocin Approved, Vet_approved Phase 4,Phase 2,Phase 1,Early Phase 1 50-56-6 439302 53477758
17
Citalopram Approved Phase 4,Phase 3,Phase 2 59729-33-8 2771
18
Norepinephrine Approved Phase 4,Phase 3,Phase 1,Early Phase 1 51-41-2 439260
19
Hydrocortisone Approved, Vet_approved Phase 4,Phase 2,Phase 3 50-23-7 5754 657311
20
Lorazepam Approved Phase 4 846-49-1 3958
21
Midazolam Approved, Illicit Phase 4,Phase 3,Phase 2 59467-70-8 4192
22
Ketamine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 6740-88-1 3821
23
Naltrexone Approved, Investigational, Vet_approved Phase 4,Phase 2 16590-41-3 5360515
24
Asenapine Approved Phase 4 85650-56-2, 65576-45-6 3001386
25
Clonazepam Approved, Illicit Phase 4 1622-61-3 2802
26
Eszopiclone Approved Phase 4 138729-47-2 969472
27
Ziprasidone Approved Phase 4,Phase 3,Phase 2 146939-27-7 60854
28
Histamine Approved, Investigational Phase 4 75614-87-8, 51-45-6 774
29
Mianserin Approved Phase 4 24219-97-4 4184
30
Mirtazapine Approved Phase 4 85650-52-8, 61337-67-5 4205
31
Memantine Approved, Investigational Phase 4 19982-08-2 4054
32
Doxazosin Approved Phase 4,Phase 2,Phase 1 74191-85-8 3157
33
Risperidone Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 106266-06-2 5073
34
Haloperidol Approved Phase 4,Phase 3 52-86-8 3559
35
Hydroxyzine Approved Phase 4 68-88-2 3658
36
Morphine Approved, Investigational Phase 4,Phase 2 57-27-2 5288826
37
Valproic Acid Approved, Investigational Phase 4,Phase 3 99-66-1 3121
38
Vortioxetine Approved Phase 4 508233-74-7 9966051
39
Suvorexant Approved Phase 4 1030377-33-3
40
Levodopa Approved Phase 4 59-92-7 6047
41
Carbon monoxide Approved Phase 4 630-08-0 281
42 tannic acid Approved, Nutraceutical Phase 4,Phase 3
43
Melatonin Approved, Nutraceutical, Vet_approved Phase 4 73-31-4 896
44
Caffeine Approved, Nutraceutical Phase 4 58-08-2 2519
45
Butyric Acid Experimental Phase 4,Phase 3,Phase 2 107-92-6 264
46
decanoic acid Experimental Phase 4,Phase 3 334-48-5 2969
47 Adjuvants, Anesthesia Phase 4,Phase 3,Phase 2,Phase 1
48 Anesthetics Phase 4,Phase 3,Phase 2,Phase 1
49 Anesthetics, General Phase 4,Phase 3,Phase 2,Phase 1
50 Anesthetics, Intravenous Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 1234)
id Name Status NCT ID Phase
1 Transcranial Magnetic Stimulation for Post-Traumatic Stress Disorder Unknown status NCT00134446 Phase 4
2 Prevention of Posttraumatic Stress Disorder (PTSD) With Diazepam Unknown status NCT01221883 Phase 4
3 Tramadol Extended-Release (ER) for Posttraumatic Stress Disorder (PTSD) Unknown status NCT01517711 Phase 4
4 Add on Study on Δ9-THC Treatment for Posttraumatic Stress Disorders (PTSD) Unknown status NCT00965809 Phase 4
5 Predictors of Treatment Response to Fluoxetine in PTSD Following a Recent History of War Zone Stress Exposure Unknown status NCT00633685 Phase 4
6 A Randomized Cross Over Trial of Two Treatments for Obstructive Sleep Apnea in Veterans With Post Traumatic Stress Disorder Unknown status NCT01535586 Phase 4
7 Amantadine for Treatment of Symptoms of the Post-Traumatic Confusional State Unknown status NCT00693121 Phase 4
8 Effect of Propranolol on Preventing Posttraumatic Stress Disorder Completed NCT00158262 Phase 4
9 Secondary Prevention With Paroxetine vs. Placebo in Subthreshold Posttraumatic Stress Disorder (PTSD) Completed NCT00560612 Phase 4
10 Treatment for Alcoholism and Post-Traumatic Stress Disorder (Naltrexone) Completed NCT00006489 Phase 4
11 An Open Label Pilot Study of Adjunctive Asenapine for the Treatment of Posttraumatic Stress Disorder Completed NCT01587118 Phase 4
12 Cognitive Behavioral Therapy Versus Sertraline in the Treatment of Post-Traumatic Stress Disorder Completed NCT00391430 Phase 4
13 Clonazepam and Paroxetine for Rapid Treatment of Post-Traumatic Stress Disorder Completed NCT00025740 Phase 4
14 Eszopiclone for the Treatment of Posttraumatic Stress Disorder Completed NCT01605253 Phase 4
15 Placebo Controled Clinical Trial Using Topiramate To Treat Posttraumatic Stress Disorder (PTSD) Patients. Completed NCT00725920 Phase 4
16 Eszopiclone for Sleep Disturbance and Nightmares in Post-Traumatic Stress Disorder Completed NCT00120250 Phase 4
17 Prazosin Treatment for Combat Trauma PTSD (Post-Traumatic Stress Disorder) Nightmares and Sleep Disturbance Completed NCT00108420 Phase 4
18 Geodon (Ziprasidone) for Posttraumatic Stress Disorder Completed NCT00208208 Phase 4
19 Topiramate in the Treatment of Posttraumatic Stress Disorder in Civilians Completed NCT00208130 Phase 4
20 Brain Markers of Treatment Response in Post-Traumatic Stress Disorder (PTSD) Completed NCT00700999 Phase 4
21 Topiramate Treatment of Alcohol Use Disorders in Veterans With Post Traumatic Stress Disorder (PTSD): A Pilot Controlled Trial of Augmentation Therapy Completed NCT01087736 Phase 4
22 Developing Memory Reconsolidation Blockers as Novel Post-traumatic Stress Disorder (PTSD) Treatments Completed NCT01490697 Phase 4
23 Combined Mirtazapine and SSRI Treatment of PTSD: A Placebo-Controlled Trial Completed NCT01178671 Phase 4
24 Vilazodone for the Treatment of Posttraumatic Stress Disorder Completed NCT01715519 Phase 4
25 Effects of Paxil CR on Neural Circuits in Posttraumatic Stress Disorder (PTSD) Completed NCT00672776 Phase 4
26 Topiramate in the Treatment of Post Traumatic Stress Disorder (PTSD) Completed NCT00203463 Phase 4
27 A Psychophysiologic Study of Weakening Traumatic Combat Memories With Post-Reactivation Propranolol Completed NCT00709735 Phase 4
28 Combination Treatment for Posttraumatic Stress Disorder (PTSD) After the World Trade Center (WTC) Attack Completed NCT01130103 Phase 4
29 The Effect of Intranasal Oxytocin on Emphatic Abilities in Patients With Post Traumatic Stress Disorder (PTSD) Completed NCT01325168 Phase 4
30 Effects of Escitalopram on Autonomic Reactivity in Post Traumatic Stress Disorder Completed NCT01271244 Phase 4
31 An Open-Label Trial of Memantine for Cognitive Impairment in Patients With Post-Traumatic Stress Disorder Completed NCT02258828 Phase 4
32 Telemedicine Outreach for Post Traumatic Stress in CBOCs Completed NCT00821678 Phase 4
33 A Pilot Study to Assess the Effects of Doxazosin on Polysomnography in PTSD Completed NCT01959022 Phase 4
34 Risperidone in the Treatment of PTSD in Women Survivors of Domestic Abuse and Rape Trauma Completed NCT00208182 Phase 4
35 The Outcome of Treatment of Traumatised Refugees With Psychotherapy and/or Antidepressants Completed NCT00917397 Phase 4
36 Quetiapine Treatment for Post-Traumatic Stress Disorder (PTSD) Completed NCT00237393 Phase 4
37 A Study of Sertraline to Prevent PTSD Completed NCT00182078 Phase 4
38 Evaluation of Stress Disorders Completed NCT00050804 Phase 4
39 Veterans Individual Placement and Support Towards Advancing Recovery Completed NCT01817712 Phase 4
40 The Treatment of Traumatised Refugees With Sertraline Versus Venlafaxine in Combination With Psychotherapy Completed NCT01569685 Phase 4
41 Posttraumatic Symptoms Among Toddlers and Their Parents Following Exposure to Terrorism Completed NCT00447538 Phase 4
42 Quetiapine Augmentation for Treatment-resistant PTSD Completed NCT00292370 Phase 4
43 Primary Care Intervention Strategy for Anxiety Disorders Completed NCT00347269 Phase 4
44 Influence of Hydrocortisone on Immunologic Markers and Health Care Related Quality of Life in Patients After Cardiac Surgery Completed NCT00490828 Phase 4
45 Pilot Study of Pharmaceutical and Behavioral Interventions to Treat Anxiety Disorders Completed NCT01631682 Phase 4
46 Serotonin Selective Reuptake Inhibitor Treatment of Dual Diagnosis Post-traumatic Stress Disorder and Alcohol Problems Completed NCT02504931 Phase 4
47 A Placebo-Controlled Study of Mirtazapine for PTSD Completed NCT00302107 Phase 4
48 Cardiopulmonary Resuscitation Witnessing by a Relative Completed NCT01009606 Phase 4
49 Treatments for Psychogenic Nonepileptic Seizures (NES) Completed NCT00159965 Phase 4
50 Preventing Post-Operative Delirium in Patients Undergoing a Pneumonectomy, Esophagectomy or Thoracotomy Completed NCT02213900 Phase 4

Search NIH Clinical Center for Post-Traumatic Stress Disorder

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: stress disorders, post-traumatic

Genetic Tests for Post-Traumatic Stress Disorder

Genetic tests related to Post-Traumatic Stress Disorder:

id Genetic test Affiliating Genes
1 Post-Traumatic Stress Disorder 29

Anatomical Context for Post-Traumatic Stress Disorder

MalaCards organs/tissues related to Post-Traumatic Stress Disorder:

39
Brain, Cortex, Heart, Eye, Prefrontal Cortex, Breast, Amygdala

Publications for Post-Traumatic Stress Disorder

Articles related to Post-Traumatic Stress Disorder:

(show top 50) (show all 677)
id Title Authors Year
1
COMT Val(158)Met polymorphism is associated with post-traumatic stress disorder and functional outcome following mild traumatic brain injury. ( 27769642 )
2017
2
Secondary psychotic features in refugees diagnosed with post-traumatic stress disorder: a retrospective cohort study. ( 28056884 )
2017
3
Prolonged exposure therapy for the treatment of patients diagnosed with psychogenic non-epileptic seizures (PNES) and post-traumatic stress disorder (PTSD). ( 28038392 )
2017
4
Dissociation between working memory performance and proactive interference control in post-traumatic stress disorder. ( 28077328 )
2017
5
Dissociation between amygdala and bed nucleus of the stria terminalis during threat anticipation in female post-traumatic stress disorder patients. ( 28070973 )
2017
6
Post-traumatic Stress Disorder and Complicated Grief are Common in Caregivers of Neuro-ICU Patients. ( 28054288 )
2017
7
Post-traumatic stress disorder symptom duration and remission in relation to cardiovascular disease risk among a large cohort of women. ( 28052776 )
2017
8
The effect of Elettaria cardamomum extract on anxiety-like behavior in a rat model of post-traumatic stress disorder. ( 28073098 )
2017
9
Depression and post-traumatic stress disorder in individuals with hereditary hemorrhagic telangiectasia: A cross-sectional survey. ( 28314138 )
2017
10
Exploring a post-traumatic stress disorder paradigm in Flinders sensitive line rats to model treatment-resistant depression I: bio-behavioural validation and response to imipramine. ( 27573792 )
2016
11
Neuroinflammatory genes associated with post-traumatic stress disorder: implications for comorbidity. ( 27635478 )
2016
12
'Everything just seems much more right in nature': How veterans with post-traumatic stress disorder experience nature-based activities in a forest therapy garden. ( 28070397 )
2016
13
Nature and Treatment of Comorbid Alcohol Problems and Post Traumatic Stress Disorder Among American Military Personnel and Veterans. ( 27159820 )
2016
14
Is plasma GABA level a biomarker of Post-Traumatic Stress Disorder (PTSD) severity? A preliminary study. ( 27208514 )
2016
15
Post-traumatic Stress Disorder Symptoms Among People Living with HIV/AIDS in Rural China. ( 27990584 )
2016
16
Serotonin Syndrome Following an Uncomplicated Orthopedic Surgery in a Patient With Post-Traumatic Stress Disorder. ( 27612381 )
2016
17
The Emerging Role of Mindfulness Meditation as Effective Self-Management Strategy, Part 1: Clinical Implications for Depression, Post-Traumatic Stress Disorder, and Anxiety. ( 27612338 )
2016
18
Emergence Delirium With Post-traumatic Stress Disorder Among Military Veterans. ( 28083465 )
2016
19
Treatment of Post-Traumatic Stress Disorder Nightmares at a Veterans Affairs Medical Center. ( 27999253 )
2016
20
Post-traumatic stress disorder associated with natural and human-made disasters in the World Mental Health Surveys. ( 27573281 )
2016
21
Cognitive therapy as an early treatment for post-traumatic stress disorder in children and adolescents: a randomized controlled trial addressing preliminary efficacy and mechanisms of action. ( 27976374 )
2016
22
Platelet monoamine oxidase type B, MAOB intron 13 and MAOA-uVNTR polymorphism and symptoms of post-traumatic stress disorder. ( 27112218 )
2016
23
Exploring the impact of parental post-traumatic stress disorder on military family children: A review of the literature. ( 27189880 )
2016
24
Role of the Endoplasmic Reticulum Pathway in the Medial Prefrontal Cortex in Post-Traumatic Stress Disorder Model Rats. ( 27112439 )
2016
25
Treating Post-traumatic Stress Disorder in Patients with Multiple Sclerosis: A Randomized Controlled Trial Comparing the Efficacy of Eye Movement Desensitization and Reprocessing and Relaxation Therapy. ( 27148134 )
2016
26
The feeling of discomfort during vaginal examinations, history of abuse and sexual abuse and post-traumatic stress disorder in women. ( 27603931 )
2016
27
Reliability and Validity of the Korean Version of the Symptom Checklist-Post-Traumatic Stress Disorder Scale. ( 27134501 )
2016
28
Rescaling the Post-Traumatic Stress Disorder Checklist for Use in Primary Care. ( 27612344 )
2016
29
Serum brain-derived neurotrophic factor (BDNF) concentrations in pregnant women with post-traumatic stress disorder and comorbid depression. ( 27193345 )
2016
30
Evidence for the changes of pituitary volumes in patients with post-traumatic stress disorder. ( 28013068 )
2016
31
Effect of Stellate Ganglion Block on Specific Symptom Clusters for Treatment of Post-Traumatic Stress Disorder. ( 27612365 )
2016
32
Integrated Exposure-Based Therapy for Co-Occurring Post Traumatic Stress Disorder (PTSD) and Substance Dependence: Predictors of Change in PTSD Symptom Severity. ( 27854264 )
2016
33
Management of breast cancer in an Asian man with post-traumatic stress disorder: a case report. ( 27113572 )
2016
34
Military veterans and canine assistance for post-traumatic stress disorder: A narrative review of the literature. ( 27179660 )
2016
35
Intergenerational transmission of post-traumatic stress disorder in Australian Vietnam veterans' families. ( 28032331 )
2016
36
Toward Preventing Post-Traumatic Stress Disorder: Development and Testing of a Pilot Predeployment Stress Inoculation Training Program. ( 27612367 )
2016
37
The latent structure of post-traumatic stress disorder among Arabic-speaking refugees receiving psychiatric treatment in Denmark. ( 27596249 )
2016
38
Genome-wide gene-based analysis suggests an association between Neuroligin 1 (NLGN1) and post-traumatic stress disorder. ( 27219346 )
2016
39
Post-traumatic Stress Disorder Symptoms and Mental Health over Time among Low-Income Women at Increased Risk of HIV in the U.S. ( 27180715 )
2016
40
Iron-induced neuronal damage in a rat model of post-traumatic stress disorder. ( 27208615 )
2016
41
Chronic Pain Types Differ in Their Reported Prevalence of Post -Traumatic Stress Disorder (PTSD) and There Is Consistent Evidence That Chronic Pain Is Associated with PTSD: An Evidence-Based Structured Systematic Review. ( 27188666 )
2016
42
Post-War Research on Post-Traumatic Stress Disorder. Part I. Research before 1989. ( 27992887 )
2016
43
Perfusion Deficits and Functional Connectivity Alterations in Memory-Related Regions of Patients with Post-Traumatic Stress Disorder. ( 27213610 )
2016
44
Growing older with post-traumatic stress disorder. ( 27170071 )
2016
45
General practitioners knowledge and management of whiplash associated disorders and post-traumatic stress disorder: implications for patient care. ( 27440111 )
2016
46
Trauma memory characteristics and the development of acute stress disorder and post-traumatic stress disorder in youth. ( 27467024 )
2016
47
Post-traumatic Stress Disorder and Cardiovascular Disease. ( 27566327 )
2016
48
Post-Traumatic Stress Disorder and It's Predictors Among Tibetan Adolescents 3Years After the High-Altitude Earthquake in China. ( 27654243 )
2016
49
Post-traumatic stress disorder and depression among adult survivors 8 years after the 2008 Wenchuan earthquake in China. ( 28006696 )
2016
50
Breaking down the silos of treatment for post-traumatic stress disorder: integrating mind and body. ( 27169961 )
2016

Variations for Post-Traumatic Stress Disorder

Expression for Post-Traumatic Stress Disorder

Search GEO for disease gene expression data for Post-Traumatic Stress Disorder.

Pathways for Post-Traumatic Stress Disorder

Pathways related to Post-Traumatic Stress Disorder according to GeneCards Suite gene sharing:

(show all 19)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.23 ADCYAP1 ADCYAP1R1 CNR1 CRH CRHR1 DRD2
2
Show member pathways
12.73 BDNF CNR1 CRH CRHR1 POMC
3
Show member pathways
12.22 ADCYAP1 ADCYAP1R1 CRH CRHR1
5
Show member pathways
12.06 ADCYAP1R1 BDNF DRD2 NPY
6
Show member pathways
11.83 BDNF DRD2 MAOA
7 11.81 HTR2A MAOA SLC6A4
8 11.76 IL1B MAOA POMC RORA
9 11.72 ADCYAP1 ADCYAP1R1 CRH CRHR1 POMC
10 11.68 CRH CRHR1 POMC
11 11.6 FKBP5 NR3C1 POMC
12 11.49 ADCYAP1 ADCYAP1R1 BDNF HTR2A IL1B MAOA
13
Show member pathways
11.24 IL1B MAOA SLC6A4
14 10.99 HTR2A MAOA SLC6A4
15
Show member pathways
10.93 COMT MAOA SLC6A4
16 10.7 COMT MAOA
17
Show member pathways
10.69 COMT MAOA
18
Show member pathways
10.54 ADCYAP1 ADCYAP1R1
19 9.98 CRH CRHR1 POMC

GO Terms for Post-Traumatic Stress Disorder

Cellular components related to Post-Traumatic Stress Disorder according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 axon GO:0030424 8.92 CNR1 COMT DRD2 HTR2A

Biological processes related to Post-Traumatic Stress Disorder according to GeneCards Suite gene sharing:

(show all 28)
id Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 9.93 ADCYAP1 BDNF IL1B POMC
2 neuropeptide signaling pathway GO:0007218 9.8 ADCYAP1 NPY POMC
3 memory GO:0007613 9.69 CNR1 HTR2A SLC6A4
4 sensory perception of pain GO:0019233 9.65 ADCYAP1 CNR1 HTR2A
5 synaptic transmission, dopaminergic GO:0001963 9.63 CRH DRD2
6 negative regulation of synaptic transmission, glutamatergic GO:0051967 9.62 DRD2 HTR2A
7 dopamine metabolic process GO:0042417 9.61 COMT DRD2
8 negative regulation of voltage-gated calcium channel activity GO:1901386 9.61 CRHR1 DRD2
9 regulation of synaptic transmission, GABAergic GO:0032228 9.6 CNR1 DRD2
10 parturition GO:0007567 9.59 CRH CRHR1
11 behavior GO:0007610 9.58 HTR2A NPY
12 neurotransmitter catabolic process GO:0042135 9.58 COMT MAOA
13 positive regulation of cAMP biosynthetic process GO:0030819 9.58 ADCYAP1 ADCYAP1R1 CRH
14 negative regulation of potassium ion transport GO:0043267 9.57 ADCYAP1 HTR2A
15 catecholamine metabolic process GO:0006584 9.56 COMT MAOA
16 regulation of appetite GO:0032098 9.55 NPY POMC
17 positive regulation of growth hormone secretion GO:0060124 9.54 ADCYAP1 DRD2
18 response to cocaine GO:0042220 9.54 CNR1 CRH DRD2
19 positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway GO:0010579 9.52 ADCYAP1 CRHR1
20 dopamine catabolic process GO:0042420 9.49 COMT MAOA
21 female pregnancy GO:0007565 9.46 ADCYAP1 COMT CRH CRHR1
22 positive regulation of fever generation GO:0031622 9.43 CNR1 IL1B
23 negative regulation of blood pressure GO:0045776 9.43 CNR1 CRH DRD2
24 response to drug GO:0042493 9.43 ADCYAP1R1 COMT CRH DRD2 HTR2A SLC6A4
25 negative regulation of dopamine secretion GO:0033602 9.32 CNR1 DRD2
26 response to ethanol GO:0045471 9.02 ADCYAP1 ADCYAP1R1 CNR1 CRH DRD2
27 positive regulation of transcription from RNA polymerase II promoter GO:0045944 10.11 ADCYAP1 DRD2 IL1B NR3C1 POMC RORA
28 signal transduction GO:0007165 10.11 ADCYAP1R1 CNR1 CRH CRHR1 DRD2 HTR2A

Molecular functions related to Post-Traumatic Stress Disorder according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 G-protein coupled receptor activity GO:0004930 9.8 ADCYAP1R1 CNR1 CRHR1 DRD2 HTR2A NPY
2 receptor binding GO:0005102 9.55 ADCYAP1 CRH DRD2 NPY POMC
3 drug binding GO:0008144 9.43 CNR1 DRD2 HTR2A
4 neuropeptide hormone activity GO:0005184 9.13 ADCYAP1 CRH NPY
5 hormone activity GO:0005179 8.92 ADCYAP1 CRH NPY POMC

Sources for Post-Traumatic Stress Disorder

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