Aliases & Classifications for Postherpetic Neuralgia

MalaCards integrated aliases for Postherpetic Neuralgia:

Name: Postherpetic Neuralgia 50 36 69

External Ids:

KEGG 36 H01624
UMLS 69 C0032768

Summaries for Postherpetic Neuralgia

NINDS : 50 Shingles (herpes zoster) is an outbreak of rash or blisters on the skin that is caused by the same virus that causes chickenpox — the varicella-zoster virus. The first sign of shingles is often burning or tingling pain (which can be severe), or sometimes numbness or itch,generally on one side of the body. After several days or a week, a rash of fluid-filled blisters, similar to chickenpox, appears in one area on one side of the body. Shingles pain can be mild or intense.  Some people have mostly itching; some feel pain from the gentlest touch or breeze.  The most common location for shingles is a band, called a dermatome, spanning one side of the trunk around the waistline. Anyone who has had chickenpox is at risk for shingles.  Scientists think that some of the virus particles from the original exposure to the varicella-zoster virus,leave the skin blisters and move into the nervous system.  When the varicella-zoster virus reactivates, the virus moves back down the long nerve fibers that extend from the sensory cell bodies to the skin.  The viruses multiply, the tell-tale rash erupts, and the person now has shingles.

MalaCards based summary : Postherpetic Neuralgia is related to herpes zoster and episodic pain syndrome, familial, 1, and has symptoms including sciatica and neuralgia. An important gene associated with Postherpetic Neuralgia is HLA-B (Major Histocompatibility Complex, Class I, B), and among its related pathways/superpathways are Class I MHC mediated antigen processing and presentation and Cytokine Signaling in Immune system. The drugs Lidocaine and Foscarnet have been mentioned in the context of this disorder. Affiliated tissues include skin, brain and spinal cord, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Wikipedia : 72 Postherpetic neuralgia (PHN) is nerve pain which occurs due to damage to a peripheral nerve caused by... more...

Related Diseases for Postherpetic Neuralgia

Diseases related to Postherpetic Neuralgia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 88)
# Related Disease Score Top Affiliating Genes
1 herpes zoster 11.7
2 episodic pain syndrome, familial, 1 10.9
3 neuropathy 10.6
4 pulmonary hypertension, neonatal 10.4
5 diabetic neuropathy 10.4
6 aging 10.3
7 herpes zoster ophthalmicus 10.2
8 neuronitis 10.2
9 cervicitis 10.2
10 trigeminal neuralgia 10.1
11 spinal cord injury 10.0
12 polyneuropathy 10.0
13 microscopic polyangiitis 10.0 HLA-B HLA-DRB1
14 idiopathic inflammatory myopathy 10.0 HLA-B HLA-DRB1
15 panuveitis 10.0 HLA-B HLA-DRB1
16 echinococcosis 10.0 HLA-B HLA-DRB1
17 sclerosing cholangitis 9.9 HLA-B HLA-DRB1
18 cholangitis 9.9 HLA-B HLA-DRB1
19 spondylitis 9.9
20 traumatic brain injury 9.9
21 axonal neuropathy 9.9
22 rheumatoid arthritis 9.9
23 epidural abscess 9.9
24 peptic ulcer disease 9.9
25 heart disease 9.9
26 galactorrhea 9.9
27 horner's syndrome 9.9
28 ifap syndrome with or without bresheck syndrome 9.9
29 allergic hypersensitivity disease 9.9
30 herpes simplex 9.9
31 paine syndrome 9.9
32 inflammatory spondylopathy 9.9
33 chickenpox 9.9
34 diabetic polyneuropathy 9.9
35 coronary heart disease 1 9.9
36 anxiety 9.9
37 back pain 9.9
38 dermatitis 9.9
39 chronic pain 9.9
40 contact dermatitis 9.9
41 headache 9.9
42 arthritis 9.9
43 vestibular disease 9.9
44 myoclonus 9.9
45 brain injury 9.9
46 cerebritis 9.9
47 chronic kidney failure 9.9
48 radiculopathy 9.9
49 kidney disease 9.9
50 rheumatic disease 9.9 HLA-B HLA-DRB1

Graphical network of the top 20 diseases related to Postherpetic Neuralgia:



Diseases related to Postherpetic Neuralgia

Symptoms & Phenotypes for Postherpetic Neuralgia

UMLS symptoms related to Postherpetic Neuralgia:


sciatica, neuralgia

GenomeRNAi Phenotypes related to Postherpetic Neuralgia according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-103 10.53 HLA-A HLA-B
2 Increased shRNA abundance (Z-score > 2) GR00366-A-110 10.53 HLA-B HLA-A
3 Increased shRNA abundance (Z-score > 2) GR00366-A-118 10.53 HLA-B HLA-A
4 Increased shRNA abundance (Z-score > 2) GR00366-A-156 10.53 HLA-B HLA-A
5 Increased shRNA abundance (Z-score > 2) GR00366-A-178 10.53 HLA-B HLA-A
6 Increased shRNA abundance (Z-score > 2) GR00366-A-19 10.53 HLA-B HLA-A
7 Increased shRNA abundance (Z-score > 2) GR00366-A-31 10.53 HLA-B HLA-A
8 Increased shRNA abundance (Z-score > 2) GR00366-A-7 10.53 HLA-B HLA-A
9 Increased shRNA abundance (Z-score > 2) GR00366-A-74 10.53 HLA-B HLA-A

Drugs & Therapeutics for Postherpetic Neuralgia

Drugs for Postherpetic Neuralgia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 173)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 137-58-6 3676
2
Foscarnet Approved Phase 4 4428-95-9, 63585-09-1 3415
3
Etoricoxib Approved, Investigational Phase 4,Phase 2 202409-33-4 123619
4
Pregabalin Approved, Illicit, Investigational Phase 4,Phase 3,Phase 2,Phase 1 148553-50-8 5486971
5
Gabapentin Approved, Investigational Phase 4,Phase 3,Phase 2 60142-96-3 3446
6
Carbamazepine Approved, Investigational Phase 4 298-46-4 2554
7
Furosemide Approved, Vet_approved Phase 4 54-31-9 3440
8
Acetaminophen Approved Phase 4 103-90-2 1983
9
Celecoxib Approved, Investigational Phase 4 169590-42-5 2662
10
Acetylcholine Approved Phase 4,Phase 2 51-84-3 187
11
Capsaicin Approved Phase 4,Phase 3,Phase 2,Phase 1 404-86-4 1548943
12
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
13
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 2713 9552079
14
Oxcarbazepine Approved Phase 4 28721-07-5 34312
15
gamma-Aminobutyric acid Approved, Investigational Phase 4,Phase 3,Phase 2 56-12-2 119
16
Pitavastatin Approved Phase 4 147511-69-1, 147526-32-7 5282452 6366718
17
Phosphonoacetic Acid Experimental Phase 4 4408-78-0 546
18 Acyclovir Phase 4,Phase 3,Phase 2
19 Analgesics Phase 4,Phase 3,Phase 2,Phase 1
20 calcium channel blockers Phase 4,Phase 3,Phase 2,Phase 1
21 diuretics Phase 4,Phase 1,Phase 2
22 Reverse Transcriptase Inhibitors Phase 4
23 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Phase 1
24 Sodium Channel Blockers Phase 4,Phase 3,Phase 2,Phase 1
25 Narcotics Phase 4,Phase 2,Phase 3
26 Natriuretic Agents Phase 4,Phase 1,Phase 2
27 Tranquilizing Agents Phase 4,Phase 3,Phase 2,Phase 1
28 Cyclooxygenase 2 Inhibitors Phase 4,Phase 2
29 Cyclooxygenase Inhibitors Phase 4,Phase 2,Phase 1
30 Analgesics, Non-Narcotic Phase 4,Phase 2,Phase 1
31 Analgesics, Opioid Phase 4,Phase 2,Phase 3
32 Anesthetics Phase 4,Phase 3,Phase 2,Phase 1
33 Nucleic Acid Synthesis Inhibitors Phase 4
34 Anesthetics, Local Phase 4,Phase 2,Phase 1
35 Diuretics, Potassium Sparing Phase 4,Phase 3,Phase 2,Phase 1
36 Anti-Anxiety Agents Phase 4,Phase 3,Phase 2,Phase 1
37 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
38 Anti-Arrhythmia Agents Phase 4,Phase 2,Phase 1
39 Anticonvulsants Phase 4,Phase 3,Phase 2,Phase 1
40 Anti-Infective Agents Phase 4,Phase 3,Phase 2
41 Anti-Inflammatory Agents Phase 4,Phase 2,Phase 1
42 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 2,Phase 1
43 Anti-Retroviral Agents Phase 4
44 Psychotropic Drugs Phase 4,Phase 3,Phase 2,Phase 1
45 Antirheumatic Agents Phase 4,Phase 2,Phase 1
46 Calcium, Dietary Phase 4,Phase 3,Phase 2,Phase 1
47 Antiviral Agents Phase 4,Phase 3,Phase 2,Phase 1
48 Chlorhexidine gluconate Phase 4
49 abobotulinumtoxinA Phase 4,Phase 2
50 Sodium Potassium Chloride Symporter Inhibitors Phase 4

Interventional clinical trials:

(show top 50) (show all 199)

# Name Status NCT ID Phase Drugs
1 Evaluation of the Efficacy, Tolerability and Safety of Etoricoxib (Arcoxia) in Patients With Neuropathic Pain Unknown status NCT01264237 Phase 4 Etoricoxib;Placebo
2 Efficacy and Safety of Foscarnet Sodium and Sodium Chloride Injection in Patients With Herpes Zoster Unknown status NCT02151240 Phase 4 Foscarnet Sodium;Acyclovir
3 Pregabalin for Treatment of Patients With Postherpetic Neuralgia (PHN) Completed NCT01455428 Phase 4 Lyrica (pregabalin);Placebo
4 A Study of the Efficacy and Safety of Pregabalin for the Treatment of Diabetic Peripheral Neuropathy or Postherpetic Neuralgia Completed NCT00629681 Phase 4 Pregabalin
5 Study of Pregabalin Therapy for Pain Relief in Subjects With Post-Herpetic Neuralgia Completed NCT00159666 Phase 4 pregabalin
6 A Study of the Effectiveness And Safety Of Lidoderm® As Add-On Treatment in Patients With Postherpetic Neuralgia, Diabetic Neuropathy, or Low Back Pain Completed NCT00904020 Phase 4 Lidoderm
7 Pregabalin Treatment Of Peripheral Neuropathic Pain Associated With Diabetic Peripheral NeP (DPN), Postherpetic Neuralgia (PHN), HIV-related NeP (HIV), and Chemotherapy Induced NeP Completed NCT00407511 Phase 4 Pregabalin
8 Efficacy Study of Botox to Treat Neuropathic Pain Completed NCT00527202 Phase 4 botulinum toxin A and saline
9 A Study to Compare QUTENZA With Pregabalin for the Treatment of Peripheral Neuropathic Pain (PNP) After 8 Weeks of Treatment Completed NCT01713426 Phase 4 Qutenza;Pregabalin
10 Botulinum Toxin in Peripheral Neuropathic Pain Completed NCT01251211 Phase 4 botulinum toxin type A
11 LPHP-Philos-PHN Conservative Treatment Completed NCT00205959 Phase 4
12 A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions Completed NCT00904202 Phase 4 Placebo Capsules + Placebo Patch;Placebo capsules + Lidoderm®;Gabapentin + Placebo;Gabapentin + Lidoderm®;Gabapentin 300 mg capsules 1800 mg/day + placebo patch;Gabapentin 1800 mg/day + Lidoderm patch
13 Method of Pre-treatment for Application of QUTENZA Capsaicin 8% Patch Completed NCT01416116 Phase 4 QUTENZA;Lidocaine;Tramadol
14 Oxcarbazepine for the Treatment of Chronic Peripheral Neuropathic Pain Completed NCT01302275 Phase 4 Oxcarbazepine
15 Early Diuresis Following Colorectal Surgery Completed NCT02351934 Phase 4 Furosemide;Celecoxib;Gabapentin
16 Dressing: Frequency of Change and Evaluation of an Antiseptic-Impregnated Catheter Dressing in ICU Patients Completed NCT00417235 Phase 4
17 A Study on Health - Related Quality of Life in Patients With Rheumatic Diseases Taking Tramadol 37.5mg/Acetaminophen 325mg Tablets Completed NCT00642837 Phase 4 Tramadol/acetaminophen;Tramadol/acetaminophen;Tramadol/acetaminophen;Tramadol/acetaminophen;Tramadol/acetaminophen;Tramadol/acetaminophen;Tramadol/acetaminophen;Tramadol/acetaminophen;Tramadol/acetaminophen;Tramadol/acetaminophen
18 Acupuncture in Herpes Zoster Neuralgia (ACUZoster) Recruiting NCT00885586 Phase 4 gabapentine
19 Dyslipidemia of Obesity Intervention in Teens Not yet recruiting NCT02956590 Phase 4 Pitavastatin;Placebo
20 Pilot Study Of Pregabalin And Prediction Of Treatment Response In Patients With Postherpetic Neuralgia Terminated NCT01603394 Phase 4 pregabalin
21 Preemptive Analgesia Following Uterine Artery Embolization Terminated NCT01555073 Phase 4 pregabalin/celecoxib;pregabalin/placebo;celecoxib/placebo;Placebo group
22 Efficacy, Safety, Tolerability and Pharmacokinetics of Concomitant Administration of Tramadol With Duloxetine or Pregabalin Withdrawn NCT01116531 Phase 4 Tramadol;Duloxetine;Pregabalin
23 Efficacy and Safety of Pregabalin Sustained Release Tablet for Postherpetic Neuralgia Unknown status NCT02868801 Phase 3 Placebo;Pregabalin SR tablet 165mg/day;Pregabalin SR tablet 330mg/day;Pregabalin SR tablet 660mg/day
24 Study of PHN131 in Patients After Surgery Unknown status NCT02193620 Phase 2, Phase 3 PHN131 soft capsule with Nalbuphine HCl 60 mg/cap;Placebo soft capsules;Dicofenac
25 Effect of Opioids in Neuropathic Pain in Postherpetic Patients Unknown status NCT01102101 Phase 3 Remifentanil
26 A Novel Non Invasive Brain Stimulation Based Treatment for Chronic Low Back Pain (CLBP) Unknown status NCT02393391 Phase 2, Phase 3
27 Methadone in Post-Herpetic Neuralgia Pain Completed NCT01752699 Phase 3 Methadone;Placebo
28 Safety And Efficacy Study Of Once Daily Controlled Release Pregabalin In The Treatment Of Patients With Postherpetic Neuralgia Completed NCT01270828 Phase 3 Pregabalin;placebo
29 Safety and Efficacy of Gabapentin in Postherpetic Neuralgia Completed NCT00335933 Phase 3 Gabapentin extended-release tablets
30 A Confirmatory Study of Fentanyl in Participants With Post-herpetic Neuralgia, Complex Regional Pain Syndrome or Postoperative Pain Syndrome Completed NCT01008553 Phase 3 Fentanyl;Placebo
31 Safety and Efficacy of Gabapentin in Postherpetic Neuralgia Completed NCT00636636 Phase 3 Gabapentin Extended Release tablets;Placebo
32 DS-5565 Phase III Study for Renal Impairment in Japanese Subjects Completed NCT02607280 Phase 3 DS-5565
33 Study of NGX-4010 for the Treatment of Postherpetic Neuralgia Completed NCT00300222 Phase 3 NGX-4010
34 Study of NGX-4010 for the Treatment of Postherpetic Neuralgia Completed NCT00115310 Phase 3 NGX-4010
35 To Evaluate Long-Term Safety and Efficacy of Pregabalin in Patients With Postherpetic Neuralgia. Completed NCT00150436 Phase 3 Pregabalin
36 A 13-Week, Randomized, Double-Blind, Multicenter, Placebo-Controlled Study Of Pregabalin For Postherpetic Neuralgia Completed NCT00394901 Phase 3 Placebo;Pregabalin;Pregabalin;Pregabalin
37 Efficacy, Safety and Tolerability Study of TAK-583 in Subjects With Postherpetic Neuralgia Completed NCT00377598 Phase 2, Phase 3 TAK-583;TAK-583;TAK-583;TAK-583;Placebo
38 NGX-4010 for the Treatment of Postherpetic Neuralgia Completed NCT00061776 Phase 2, Phase 3 Capsaicin Dermal Patch
39 Evaluating E2007 (Perampanel) in Patients With Painful Diabetic Neuropathy (PDN) or Post-Herpetic Neuralgia (PHN) Completed NCT00592904 Phase 2, Phase 3 E2007
40 Controlled Study of NGX-4010 for the Treatment of Postherpetic Neuralgia Completed NCT00068081 Phase 3 Capsaicin Dermal Patch
41 Efficacy and Safety of Topical Versus Systemic Treatment in Postherpetic Neuralgia and Diabetic Polyneuropathic Pain Completed NCT00414349 Phase 3 Topical analgesic;oral intake;Topical analgesic
42 A Long-Term Study To Evaluate Safety And Efficacy Of Pregabalin For Postherpetic Neuralgia Completed NCT00424372 Phase 3 pregabalin
43 Shingles Prevention Study Completed NCT00007501 Phase 3
44 Phase III Randomized Controlled Study of Morphine and Nortriptyline in the Management of Postherpetic Neuralgia Completed NCT00004390 Phase 3 desipramine;methadone;morphine;nortriptyline
45 Study To Evaluate Efficacy, Safety And Tolerability Of Lyrica In Patients With Painful Diabetic Peripheral Neuropathy Completed NCT01332149 Phase 3 Pregabalin;Placebo matched with pregabalin
46 Efficacy Study Measuring the Impact of Pregabalin on Peripheral Neuropathic Pain. Completed NCT00219544 Phase 3 Pregabalin (Lyrica);Pregabalin (Lyrica);Pregabalin (Lyrica);Placebo
47 Study to Evaluate Efficacy, Safety and Immunogenicity of GlaxoSmithKline (GSK) Biologicals' Herpes Zoster (HZ) Vaccine GSK1437173A in Adults Aged 70 Years and Older Completed NCT01165229 Phase 3
48 Effect of Oral Pregabalin on Spinal Neurotransmitters in Patients Undergoing Knee Replacement Completed NCT00729690 Phase 3 Pregabalin;Pregabalin;Placebo
49 Postoperative Pain and Morphine Consumption After Mastectomy - Lyrica Completed NCT01391858 Phase 3 lyrica
50 Safety and Efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg as an Analgesic for Short-Term Treatment in Female Subjects Suffering From Moderate-to-Severe Pain and Burning Upon Urination Associated With Uncomplicated Urinary Tract Infections ( Completed NCT01650051 Phase 3 Placebo of Phenazopyridine Hydrochloride Tables, USP 200 mg;Phenazopyridine Hydrochloride Tables, USP 200 mg

Search NIH Clinical Center for Postherpetic Neuralgia

Genetic Tests for Postherpetic Neuralgia

Anatomical Context for Postherpetic Neuralgia

MalaCards organs/tissues related to Postherpetic Neuralgia:

38
Skin, Brain, Spinal Cord, Testes, Endothelial, Liver, Dorsal Root Ganglion

Publications for Postherpetic Neuralgia

Articles related to Postherpetic Neuralgia:

(show top 50) (show all 618)
# Title Authors Year
1
Efficacy of Pain Relief in Different Postherpetic Neuralgia Therapies: A Network Meta-Analysis. ( 29357328 )
2018
2
Associations of Perceived Mental Stress, Sense of Purpose in Life, and Negative Life Events With the Risk of Incident Herpes Zoster and Postherpetic Neuralgia: The SHEZ Study. ( 29036443 )
2018
3
Herpes zoster chronification to postherpetic neuralgia induces brain activity and grey matter volume change. ( 29423004 )
2018
4
Sensory symptom profiles differ between trigeminal and thoracolumbar postherpetic neuralgia. ( 29430564 )
2018
5
Incidence and costs of herpes zoster and postherpetic neuralgia in German adults aged a8Y50 years: A prospective study. ( 29428228 )
2018
6
Effectiveness of continuous epidural analgesia on acute herpes zoster and postherpetic neuralgia: A retrospective study. ( 29384888 )
2018
7
Postherpetic Neuralgia: Practical Experiences Return to Traditional Chinese Medicine. ( 28712474 )
2017
8
Association of serum Ninjurin2 levels with neurologic damage and postherpetic neuralgia occurrence: an observational cohort study in chinese herpeszoster patients. ( 29069724 )
2017
9
Treatment Option for Refractory Postherpetic Neuralgia - Transversus Abdominis Plane (TAP) Block: Two Case Reports. ( 28920039 )
2017
10
Herpes Zoster and Postherpetic Neuralgia: Prevention and Management. ( 29431387 )
2017
11
Neuromodulation in Postherpetic Neuralgia: Case Reports and Review of the Literature. ( 29016994 )
2017
12
Postherpetic Neuralgia Presenting as Delusional Parasitosis: A Case Series. ( 28615772 )
2017
13
Abnormal Local Brain Activity Beyond the Pain Matrix in Postherpetic Neuralgia Patients: A Resting-State Functional MRI Study. ( 28158166 )
2017
14
Dose-response of pregabalin for diabetic peripheral neuropathy, postherpetic neuralgia, and fibromyalgia. ( 28967801 )
2017
15
Subcutaneous Injection of Triamcinolone and Lidocaine to Prevent Postherpetic Neuralgia. ( 28727702 )
2017
16
Local Brain Activity Differences Between Herpes Zoster and Postherpetic Neuralgia Patients: A Resting-State Functional MRI Study. ( 28727713 )
2017
17
Effect of Zhuang medicine medicated thread moxibustion on protomics in serum of postherpetic neuralgia patient with Herpes zoster. ( 28671082 )
2017
18
Cost of shingles: population based burden of disease analysis of herpes zoster and postherpetic neuralgia. ( 28086817 )
2017
19
PainVisionAr Apparatus for Assessment of Efficacy of Pulsed Radiofrequency Combined with Pharmacological Therapy in the Treatment of Postherpetic Neuralgia and Correlations with Measurements. ( 28357404 )
2017
20
The Effect of Early Use of Supplemental Therapy on Preventing Postherpetic Neuralgia: A Systematic Review and Meta-analysis. ( 28934778 )
2017
21
Ultrasound-Guided Selective Cervical Root Injection for Postherpetic Neuralgia. ( 28346307 )
2017
22
Glossopharyngeal Postherpetic Neuralgia Palliated With Fluoroscopic-Guided Nerve Block: A Case Report. ( 28925505 )
2017
23
Effect of Concomitant Pain Medications on Response to Pregabalin in Patients with Postherpetic Neuralgia or Spinal Cord Injury-Related Neuropathic Pain. ( 28072797 )
2017
24
Postherpetic neuralgia, diabetic neuropathy, and trigeminal neuralgia - Chronic peripheral neuropathic pain in 58,480 rural Italian primary care patients. ( 29026761 )
2017
25
White matter microstructure degenerates in patients with postherpetic neuralgia. ( 28729077 )
2017
26
Effect of Single Intra-cutaneous Injection for Acute Thoracic Herpes Zoster and Incidence of Postherpetic Neuralgia. ( 29153295 )
2017
27
Comparing serum microRNA levels of acute herpes zoster patients with those of postherpetic neuralgia patients. ( 28225487 )
2017
28
Safety and Efficacy of a Topical Sodium Channel Inhibitor (TV-45070) in Patients With Postherpetic Neuralgia (PHN): A Randomized, Controlled, Proof-of-Concept, Crossover Study, With a Subgroup Analysis of the Nav1.7 R1150W Genotype. ( 28266963 )
2017
29
Earlier treatment improves the chances of complete relief from postherpetic neuralgia. ( 28757922 )
2017
30
Botulinum Toxin A Might Be an Alternative or Adjunct Therapy for the Treatment of Trigeminal and Postherpetic Neuralgia. ( 28865822 )
2017
31
Glucocorticoids - Efficient analgesics against postherpetic neuralgia? ( 28850413 )
2017
32
Subcutaneous Injection of Botulinum Toxin-A in Postherpetic Neuralgia During Pregnancy. ( 29184352 )
2017
33
Treatment patterns of postherpetic neuralgia patients before and after the launch of pregabalin and its effect on medical costs: Analysis of Japanese claims data provided by Japan Medical Data Center. ( 28256737 )
2017
34
Transdermal oxycodone patch for the treatment of postherpetic neuralgia: a randomized, double-blind, controlled trial. ( 28415907 )
2017
35
Postherpetic Neuralgia and Trigeminal Neuralgia. ( 29359044 )
2017
36
Pulsed Radiofrequency to the Dorsal Root Ganglion in Acute Herpes Zoster and Postherpetic Neuralgia. ( 28339440 )
2017
37
Impact of topical 5% lidocaine-medicated plasters on sleep and quality of life in patients with postherpetic neuralgia. ( 26821240 )
2016
38
Association of human leukocyte antigen with postherpetic neuralgia in Koreans. ( 27457498 )
2016
39
Relationship between pain relief, reduction in pain-associated sleep interference, and overall impression of improvement in patients with postherpetic neuralgia treated with extended-release gabapentin. ( 27037091 )
2016
40
Quantification of risk factors for postherpetic neuralgia in herpes zoster patients: A cohort study. ( 27287218 )
2016
41
Price of pain: population-based cohort burden of disease analysis of medication cost of herpes zoster and postherpetic neuralgia. ( 27536159 )
2016
42
Factors Associated with Increased Risk for Clinical Insomnia in Patients with Postherpetic Neuralgia: A Retrospective Cross-Sectional Study. ( 27073226 )
2016
43
Stellate Ganglion Block for Debilitating Photophobia Secondary to Trigeminal, Postherpetic Neuralgia. ( 27378524 )
2016
44
Pigmented Contact Dermatitis Resulting from Self-medication for Postherpetic Neuralgia. ( 27293266 )
2016
45
Efficacy of continuous epidural block in acute herpes zoster: Incidence and predictive factors of postherpetic neuralgia, a retrospective single-center study. ( 27512887 )
2016
46
Early application of low-level laser may reduce the incidence of postherpetic neuralgia (PHN). ( 27543213 )
2016
47
Bipolar High-Voltage, Long-Duration Pulsed Radiofrequency Improves Pain Relief in Postherpetic Neuralgia. ( 27389115 )
2016
48
Microstructural Abnormalities in Gray Matter of Patients with Postherpetic Neuralgia: A Diffusional Kurtosis Imaging Study. ( 27228526 )
2016
49
Systematic Review and Meta-analysis of the Efficacy of Oral Medications Compared with Placebo Treatment in the Management of Postherpetic Neuralgia. ( 27472529 )
2016
50
Efficacy of low dose gabapentin in acute herpes zoster for preventing postherpetic neuralgia: a prospective controlled study. ( 26799145 )
2016

Variations for Postherpetic Neuralgia

Expression for Postherpetic Neuralgia

Search GEO for disease gene expression data for Postherpetic Neuralgia.

Pathways for Postherpetic Neuralgia

Pathways related to Postherpetic Neuralgia according to GeneCards Suite gene sharing:

(show all 19)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.92 HLA-A HLA-B HLA-DRB1
2
Show member pathways
12.83 HLA-A HLA-B HLA-DRB1
3
Show member pathways
12.47 HLA-A HLA-B HLA-DRB1
4
Show member pathways
12.35 HLA-A HLA-B HLA-DRB1
5
Show member pathways
12.27 HLA-A HLA-B HLA-DRB1
6
Show member pathways
12.03 HLA-A HLA-B
7
Show member pathways
11.99 HLA-A HLA-B HLA-DRB1
8 11.96 HLA-A HLA-B
9 11.86 HLA-A HLA-B
10 11.84 HLA-A HLA-B HLA-DRB1
11 11.74 HLA-A HLA-B
12
Show member pathways
11.72 HLA-A HLA-B
13 11.65 HLA-A HLA-B
14 11.64 HLA-A HLA-B HLA-DRB1
15
Show member pathways
11.55 HLA-A HLA-DRB1
16
Show member pathways
11.51 HLA-A HLA-DRB1
17 11.31 HLA-A HLA-B HLA-DRB1
18 10.96 HLA-A HLA-B HLA-DRB1
19 10.77 HLA-A HLA-B

GO Terms for Postherpetic Neuralgia

Cellular components related to Postherpetic Neuralgia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endoplasmic reticulum GO:0005783 9.65 HLA-A HLA-B HLA-DRB1
2 Golgi apparatus GO:0005794 9.63 HLA-A HLA-B HLA-DRB1
3 Golgi membrane GO:0000139 9.5 HLA-A HLA-B HLA-DRB1
4 early endosome membrane GO:0031901 9.43 HLA-A HLA-B
5 cell surface GO:0009986 9.43 HLA-A HLA-B HLA-DRB1
6 phagocytic vesicle membrane GO:0030670 9.4 HLA-A HLA-B
7 recycling endosome membrane GO:0055038 9.37 HLA-A HLA-B
8 MHC class I protein complex GO:0042612 9.16 HLA-A HLA-B
9 ER to Golgi transport vesicle membrane GO:0012507 9.13 HLA-A HLA-B HLA-DRB1
10 integral component of lumenal side of endoplasmic reticulum membrane GO:0071556 8.8 HLA-A HLA-B HLA-DRB1

Biological processes related to Postherpetic Neuralgia according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 immune system process GO:0002376 9.61 HLA-A HLA-B HLA-DRB1
2 immune response GO:0006955 9.58 HLA-A HLA-B HLA-DRB1
3 viral process GO:0016032 9.54 HLA-A HLA-B HLA-DRB1
4 regulation of immune response GO:0050776 9.49 HLA-A HLA-B
5 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent GO:0002479 9.48 HLA-A HLA-B
6 type I interferon signaling pathway GO:0060337 9.46 HLA-A HLA-B
7 antigen processing and presentation of peptide antigen via MHC class I GO:0002474 9.32 HLA-A HLA-B
8 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent GO:0002480 9.26 HLA-A HLA-B
9 protection from natural killer cell mediated cytotoxicity GO:0042270 9.16 HLA-A HLA-B
10 interferon-gamma-mediated signaling pathway GO:0060333 9.13 HLA-A HLA-B HLA-DRB1
11 antigen processing and presentation GO:0019882 8.8 HLA-A HLA-B HLA-DRB1

Molecular functions related to Postherpetic Neuralgia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptide antigen binding GO:0042605 8.8 HLA-A HLA-B HLA-DRB1

Sources for Postherpetic Neuralgia

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