Aliases & Classifications for Postpartum Depression

MalaCards integrated aliases for Postpartum Depression:

Name: Postpartum Depression 12 40 14
Depression, Postpartum 41 69
Maternity Blues 12 69
Post-Partum Depression 72
Depression Postpartum 51
Postnatal Depression 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9478
ICD10 32 F53
MeSH 41 D019052
NCIt 46 C92852

Summaries for Postpartum Depression

MedlinePlus : 40 Many women have the baby blues after childbirth. If you have the baby blues, you may have mood swings, feel sad, anxious or overwhelmed, have crying spells, lose your appetite, or have trouble sleeping. The baby blues most often go away within a few days or a week. The symptoms are not severe and do not need treatment. The symptoms of postpartum depression last longer and are more severe. You may also feel hopeless and worthless, and lose interest in the baby. You may have thoughts of hurting yourself or the baby. Very rarely, new mothers develop something even more serious. They may have hallucinations or try to hurt themselves or the baby. They need to get treatment right away, often in the hospital. Postpartum depression can begin anytime within the first year after childbirth. The cause is not known. Hormonal and physical changes after birth and the stress of caring for a new baby may play a role. Women who have had depression are at higher risk. If you think you have postpartum depression, tell your health care provider. Medicines, including antidepressants and talk therapy can help you get well. Dept. of Health and Human Services Office on Women's Health

MalaCards based summary : Postpartum Depression, also known as depression, postpartum, is related to trigeminal neuralgia and alexithymia, and has symptoms including mental and behavioral signs and symptoms and pelvic pain. An important gene associated with Postpartum Depression is CRH (Corticotropin Releasing Hormone), and among its related pathways/superpathways are cAMP signaling pathway and Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. The drugs Estradiol and Copper have been mentioned in the context of this disorder. Affiliated tissues include thyroid, colon and bone, and related phenotypes are behavior/neurological and endocrine/exocrine gland

Disease Ontology : 12 An endogenous depression that involves intense, sustained and sometimes disabling depression experienced by women after giving birth.

Wikipedia : 72 Postpartum depression (PPD), also called postnatal depression, is a type of mood disorder associated... more...

Related Diseases for Postpartum Depression

Diseases related to Postpartum Depression via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 128)
# Related Disease Score Top Affiliating Genes
1 trigeminal neuralgia 29.8 ESR1 SLC6A4
2 alexithymia 29.4 COMT HTR1A OXTR SLC6A4
3 anxiety 29.3 BDNF COMT CRH HTR1A MAOA SLC6A4
4 personality disorder 29.1 BDNF COMT HTR1A MAOA SLC6A4
5 mood disorder 28.4 BDNF COMT CRH HTR1A MAOA SLC6A4
6 schizophrenia 28.3 BDNF COMT HTR1A MAOA PRL SLC6A4
7 bipolar disorder 28.1 BDNF COMT CRH HTR1A MAOA PRL
8 major depressive disorder 27.9 BDNF COMT CRH HTR1A MAOA OXTR
9 migraine with or without aura 1 27.9 CALCA COMT ESR1 HTR1A MAOA SLC6A4
10 hypothalamic disease 10.5 CRH PRL
11 melancholia 10.5 CRH PRL
12 nelson syndrome 10.4 CRH PRL
13 sheehan syndrome 10.4 CRH PRL
14 schizophreniform disorder 10.4 COMT PRL
15 childhood-onset schizophrenia 10.4 COMT PRL
16 acth-secreting pituitary adenoma 10.4 CRH PRL
17 hypothyroidism, congenital, nongoitrous, 4 10.4 PRL TPO
18 dysthymic disorder 10.3 MAOA SLC6A4
19 phobia, specific 10.3 COMT MAOA
20 adrenal cortex disease 10.3 CRH PRL
21 traumatic brain injury 10.3 BDNF COMT
22 adrenal gland disease 10.3 CRH PRL
23 pathological gambling 10.3 MAOA SLC6A4
24 prolactin producing pituitary tumor 10.3 CALCA PRL
25 alcohol abuse 10.3 BDNF PRL SLC6A4
26 drug dependence 10.3 BDNF CRH SLC6A4
27 hypoadrenalism 10.3 CALCA CRH
28 avoidant personality disorder 10.2 CRH MAOA
29 retinitis pigmentosa 20 10.2 ESR1 SLC6A4
30 dystonia 1, torsion, autosomal dominant 10.2 COMT MAOA
31 specific developmental disorder 10.2 BDNF COMT SLC6A4
32 social phobia 10.2 MAOA PRL SLC6A4
33 atypical depressive disorder 10.2 CRH MAOA SLC6A4
34 endemic goiter 10.2 CALCA TPO
35 psychosexual disorder 10.2 HTR1A SLC6A4
36 pervasive developmental disorder 10.2 BDNF OXTR SLC6A4
37 oppositional defiant disorder 10.2 COMT MAOA SLC6A4
38 antisocial personality disorder 10.2 COMT MAOA SLC6A4
39 periodic limb movement disorder 10.2 HTR1A SLC6A4
40 premenstrual tension 10.2 CRH PRL
41 substance dependence 10.2 BDNF MAOA SLC6A4
42 nontoxic goiter 10.2 CALCA TPO
43 toxic diffuse goiter 10.2 CALCA TPO
44 ovarian cystic teratoma 10.1 CALCA PRL
45 mammographic density 10.1 COMT ESR1 PRL
46 metaphyseal chondrodysplasia, jansen type 10.1 CALCA CRH
47 schizoaffective disorder 10.1 BDNF COMT PRL SLC6A4
48 breast disease 10.1 COMT ESR1 PRL
49 intermittent explosive disorder 10.1 HTR1A PRL SLC6A4
50 thyroid gland disease 10.1 CALCA PRL TPO

Graphical network of the top 20 diseases related to Postpartum Depression:



Diseases related to Postpartum Depression

Symptoms & Phenotypes for Postpartum Depression

UMLS symptoms related to Postpartum Depression:


mental and behavioral signs and symptoms, pelvic pain

MGI Mouse Phenotypes related to Postpartum Depression:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.02 MAOA BDNF OXTR COMT PRL CRH
2 endocrine/exocrine gland MP:0005379 9.91 BDNF OXTR COMT PRL CRH SLC6A4
3 homeostasis/metabolism MP:0005376 9.85 HTR1A MAOA BDNF COMT PRL CRH
4 integument MP:0010771 9.5 BDNF OXTR PRL CRH SLC6A4 ESR1
5 nervous system MP:0003631 9.32 MAOA BDNF OXTR COMT PRL CRH

Drugs & Therapeutics for Postpartum Depression

Drugs for Postpartum Depression (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 191)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 2 50-28-2 5757
2
Copper Approved, Investigational Phase 4 7440-50-8 27099
3
Oxytocin Approved, Vet_approved Phase 4,Phase 2 50-56-6 53477758 439302
4
Ropivacaine Approved Phase 4,Phase 3,Phase 2 84057-95-4 175805 71273
5
Norethindrone Approved Phase 4 68-22-4 6230
6
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
7
Calcium Carbonate Approved, Investigational Phase 4 471-34-1
8
Citalopram Approved Phase 4 59729-33-8 2771
9
Sertraline Approved Phase 4,Phase 3,Phase 2 79617-96-2 68617
10
Medroxyprogesterone acetate Approved, Investigational Phase 4 71-58-9
11
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
12
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
13
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
14
Hydromorphone Approved, Illicit Phase 4 466-99-9 5284570
15
Carbetocin Approved, Investigational Phase 4 37025-55-1 16681432 71715
16 Estradiol valerate Phase 4,Phase 2 979-32-8
17
Serotonin Phase 4,Phase 3,Phase 2 50-67-9 5202
18 Central Nervous System Depressants Phase 4,Phase 3,Phase 2
19 Serotonin Agents Phase 4,Phase 3,Phase 2
20 Spermatocidal Agents Phase 4
21 Neurotransmitter Agents Phase 4,Phase 3,Phase 2
22 Contraceptive Agents Phase 4,Phase 2
23 Contraceptives, Oral Phase 4
24 Norethindrone acetate Phase 4
25 Anesthetics Phase 4,Phase 3,Phase 2
26 Hormone Antagonists Phase 4,Phase 2
27 Oxytocics Phase 4,Phase 2
28 Anesthetics, Local Phase 4,Phase 3,Phase 2
29 Hormones Phase 4,Phase 2
30 Disinfectants Phase 4
31 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2
32 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
33 Antidepressive Agents Phase 4,Phase 3,Phase 2,Early Phase 1
34 Estradiol 17 beta-cypionate Phase 4,Phase 2
35 Estradiol 3-benzoate Phase 4,Phase 2
36 Estrogens Phase 4,Phase 2
37 Polyestradiol phosphate Phase 4,Phase 2
38 Antirheumatic Agents Phase 4,Phase 3
39 Progestins Phase 4
40
Medroxyprogesterone Phase 4 520-85-4 10631
41 Analgesics Phase 4,Phase 2,Phase 3
42 Serotonin Uptake Inhibitors Phase 4,Phase 3,Phase 2
43 Muscarinic Antagonists Phase 4
44 Cholinergic Agents Phase 4
45 Narcotics Phase 4,Phase 2,Phase 3
46 Cholinergic Antagonists Phase 4
47 Gastrointestinal Agents Phase 4
48 Contraceptive Agents, Male Phase 4
49 Neurotransmitter Uptake Inhibitors Phase 4,Phase 3,Phase 2
50 Analgesics, Non-Narcotic Phase 4,Phase 2,Phase 3

Interventional clinical trials:

(show top 50) (show all 282)

# Name Status NCT ID Phase Drugs
1 Oral Contraceptive Ethinyl Estradiol Dose Effect on Postpartum Depression and Sexual Functioning Scales Unknown status NCT02210702 Phase 4 Ethinyl Estradiol 35mcg/Norethindrone 1mg;Ethinyl Estradiol 20mcg/Norethindrone 1mg
2 The Influence of Antenatal Classes on Pregnancy, Birth and Parenthood Unknown status NCT00323401 Phase 4
3 Escitalopram (Lexapro) for the Treatment of Postpartum Depression Completed NCT00833469 Phase 4 Escitalopram
4 Effectiveness of Supplemental Calcium in Preventing Postpartum Depression Completed NCT00228033 Phase 4 Elemental calcium (as carbonate)
5 Timing of Postpartum Depot Medroxyprogesterone Acetate Administration on Breastfeeding, Contraceptive Continuation, and Depression Completed NCT01463202 Phase 4 Depot medroxyprogesterone acetate;Depot medroxyprogesterone acetate
6 NEOBIFI: Clinical Trial for the Prevention and/or Reduction of the Incidence of Colics in Infants Completed NCT03219931 Phase 4 Bifidobacterium breve BR03 and Bifidobacterium breve B632;Placebos
7 Low-dose Ketamine and Postpartum Depression in Parturients With Prenatal Depression Recruiting NCT03336541 Phase 4 Ketamine;Placebo
8 Effect of Tramadol in Prevention of Postpartum Depression Recruiting NCT03309163 Phase 4 Tramadol;Hydromorphone;Ropivacaine (Epidural analgesia)
9 Impact of Local Anesthetic Wound Infiltration on Postoperative Pain Following Cesarean Delivery Recruiting NCT02829944 Phase 4 Ropivacaine;Ketorolac;Placebo
10 Effect of the Uterotonic Carbetocin on Acute Post Cesarean-Section Pain Not yet recruiting NCT02642263 Phase 4 Carbetocin
11 Oxytocin Dosing at Planned Cesarean Section and Anemia Not yet recruiting NCT03361124 Phase 4 Oxytocin
12 Postpartum Depression: Transdermal Estradiol Versus Sertraline Terminated NCT00744328 Phase 4 Transdermal Estradiol;Sertraline
13 Outcome of Postnatal Depression Screening Using Edinburgh Postnatal Depression Scale Unknown status NCT00251342 Phase 2, Phase 3
14 Postoperative Analgesia After Caesarean Section Under ALR: TAP Block Versus Catheter Scar Infiltration Unknown status NCT02184559 Phase 3 Ropivacaine
15 A Study to Evaluate SAGE-547 in Patients With Severe Postpartum Depression Completed NCT02942004 Phase 3 SAGE-547;Placebo
16 A Study to Evaluate SAGE-547 in Patients With Moderate Postpartum Depression Completed NCT02942017 Phase 3 SAGE-547;Placebo
17 Aripiprazole and Resistant Postpartum Depression Completed NCT01386086 Phase 3 aripiprazole
18 Identification and Therapy of Postpartum Depression Completed NCT00282776 Phase 3
19 Sertraline for the Prevention of Recurrent Postpartum Depression Completed NCT00276900 Phase 3 Sertraline
20 Functional Outcome in Postpartum Depression in Women Treated With Desvenlafaxine Completed NCT01527786 Phase 3 Desvenlafaxine
21 A Randomised Trial of Sertraline, Cognitive Behaviour Therapy & Combined Therapy for Postnatal Depression Completed NCT02122393 Phase 3 Sertraline
22 Effect of the 'Mother and Baby' Program on Well-Being Completed NCT00361478 Phase 3
23 Mother-Infant Psychoanalysis Project of Stockholm Completed NCT00923559 Phase 3
24 Does Fish Oil Prevent Depression in Pregnancy and Postpartum? Completed NCT00711971 Phase 2, Phase 3 EPA-rich fish oil supplement;DHA-rich fish oil supplement;placebo
25 Improving Health Outcomes for New Mothers and Babies Completed NCT00360204 Phase 3
26 Gestational Diabetes: Insulin or Oral Hypoglycemic Agents? Completed NCT01215331 Phase 3 Insulin;Metformin, glyburide and insulin
27 Vitamin B12 Supplementation During Pregnancy Completed NCT01795131 Phase 2, Phase 3
28 Treatment of Women After Severe Postpartum Haemorrhage Completed NCT01895205 Phase 3 Iron isomaltoside 1000;Red blood cell transfusion
29 Treatment of Women After Postpartum Haemorrhage Completed NCT01895218 Phase 3 Iron isomaltoside 1000
30 Hypnosis Antenatal Training for Childbirth (HATCh): a Randomised Controlled Trial Completed NCT00282204 Phase 2, Phase 3
31 The Synchronized Trial on Expectant Mothers With Depressive Symptoms by Omega-3 PUFAs (SYNCHRO) Completed NCT02166424 Phase 3
32 CODEPAD (Collaborative Outcomes of DEpression and Pain Associated With Delivery) Recruiting NCT03167905 Phase 2, Phase 3 Entonox;Meperidine;Ultiva;Fentanyl;Ropivacaine
33 A Randomized Trial of Docosahexaenoic Acid Supplementation During Pregnancy to Prevent Deep Placentation Disorders Recruiting NCT02336243 Phase 3
34 Adjunctive Use of Celecoxib in the Treatment of Bipolar Postpartum Depression Not yet recruiting NCT02726659 Phase 3 Celecoxib;Placebo
35 Oral Probiotic Supplementation in Pregnancy to Reduce Group B Streptococcus Colonization Not yet recruiting NCT03407157 Phase 3
36 Controlled Randomised Trial of Ferric Carboxymaltose and Oral Iron to Treat Postpartum Anemia Terminated NCT00929409 Phase 2, Phase 3 Ferric carboxymaltose;Ferrous sulfate tablets
37 Pilot Trial of CenteringPregnancy With Mindfulness Skills Unknown status NCT01646463 Phase 1, Phase 2
38 Evaluate SAGE-547 in Female Patients With Severe Postpartum Depression Completed NCT02285504 Phase 2 SAGE-547
39 Mom: Managing Our Mood, Part of The Family Help Program Completed NCT00795652 Phase 2
40 A Study to Evaluate SAGE-547 in Patients With Severe Postpartum Depression Completed NCT02614547 Phase 2 SAGE-547;Placebo
41 The Effect of Exercise on Preventing PostPartum Depression Completed NCT00961402 Phase 2
42 Repetitive Transcranial Magnetic Stimulation in Postpartum Depression Completed NCT01452321 Phase 2
43 Change Your Life With Seven Sheets of Paper Completed NCT02532504 Phase 2
44 Effectiveness of Sertraline Alone and Interpersonal Psychotherapy Alone in Treating Women With Postpartum Depression Completed NCT00602355 Phase 2 Sertraline;Placebo
45 Randomised Control Trial of a Complex Intervention for Postnatal Depression Completed NCT01309516 Phase 2
46 Preventing Postpartum Depression in African American Home Visiting Clients Completed NCT01175603 Phase 2
47 Depression Prevention for Pregnant Women on Public Assistance Completed NCT00601757 Phase 2
48 Acupuncture and Massage for Depression During Pregnancy Completed NCT00186654 Phase 2
49 Impact of Women's Empowerment Program for Abused Pregnant Women Completed NCT01933555 Phase 2
50 Prevention of Gestational Diabetes Through Lifestyle Modification Completed NCT01698385 Phase 2

Search NIH Clinical Center for Postpartum Depression

Cochrane evidence based reviews: depression, postpartum

Genetic Tests for Postpartum Depression

Anatomical Context for Postpartum Depression

MalaCards organs/tissues related to Postpartum Depression:

38
Thyroid, Colon, Bone, Heart, Amygdala, Testes, Cortex

Publications for Postpartum Depression

Articles related to Postpartum Depression:

(show top 50) (show all 668)
# Title Authors Year
1
Treatment of Postpartum Depression: Recommendations for the Clinician. ( 29351116 )
2018
2
Coping strategies of women with postpartum depression symptoms in rural Ethiopia: a cross-sectional community study. ( 29422037 )
2018
3
Postpartum depression and vitamin D: A systematic review. ( 29393662 )
2018
4
Relationship Between Postpartum Depression and Psychological and Biological Variables in the Initial Postpartum Period. ( 29423586 )
2018
5
Prevalence and factors associated with postpartum depression in women from single-child families. ( 29412451 )
2018
6
Preliminary Psychometric Testing of the Postpartum Depression Predictors Inventory-Revised (PDPI-R) in Portuguese Women. ( 29327321 )
2018
7
Adverse Childhood Experiences and Postpartum Depression in Home Visiting Programs: Prevalence, Association, and Mediating Mechanisms. ( 29435785 )
2018
8
Postpartum Depression and Its Long-term Impact on Children: Many New Questions. ( 29387871 )
2018
9
The role of tryptophan metabolism in postpartum depression. ( 29307018 )
2018
10
Adverse childhood experiences and intimate partner violence during pregnancy and their association to postpartum depression. ( 29310065 )
2018
11
Developing a Postpartum Depression Screening and Referral Procedure in Pediatric Primary Care. ( 29305113 )
2018
12
Incidence of and social-demographic and obstetric factors associated with postpartum depression: differences among ethnic Han and Kazak women of Northwestern China. ( 29404223 )
2018
13
Thyroid peroxidase antibodies during early gestation and the subsequent risk of first-onset postpartum depression: A prospective cohort study. ( 28850854 )
2018
14
Postpartum depression in older women. ( 29401116 )
2018
15
Digital Peer-Support Platform (7Cups) as an Adjunct Treatment for Women With Postpartum Depression: Feasibility, Acceptability, and Preliminary Efficacy Study. ( 29439944 )
2018
16
Anaemia and depletion of iron stores as risk factors for postpartum depression: a literature review. ( 29363366 )
2018
17
Comments on: insomnia, postpartum depression and estradiol in women after delivery. ( 29340844 )
2018
18
Injection of oxytocin into paraventricular nucleus reverses depressive-like behaviors in the postpartum depression rat model. ( 28889022 )
2018
19
Social Support and Postpartum Depression Revisited: The Traditional Female Role as Moderator among Mexican Women. ( 28936028 )
2017
20
Hair cortisol levels, psychological stress and psychopathological symptoms as predictors of postpartum depression. ( 28846691 )
2017
21
The effectiveness of mindfulness training on reducing the symptoms of postpartum depression. ( 28894531 )
2017
22
Economic and Health Predictors of National Postpartum Depression Prevalence: A Systematic Review, Meta-analysis, and Meta-Regression of 291 Studies from 56 Countries. ( 29449816 )
2017
23
Associations between a polymorphism in the hydroxysteroid (11-beta) dehydrogenase 1 gene, neuroticism and postpartum depression. ( 27721188 )
2017
24
Pacifiers and Exclusive Breastfeeding: Does Risk for Postpartum Depression Modify the Association? ( 28841401 )
2017
25
Antepartum Services and Symptoms of Postpartum Depression in At-Risk Women. ( 28797653 )
2017
26
Expression of Disrupted-in-schizophrenia 1 in Hippocampus in Postpartum Depression Animal Models Induced by Pre-pregnancy Stress. ( 28483022 )
2017
27
Refugee and Immigrant Women's Experience of Postpartum Depression: A Meta-Synthesis. ( 28826328 )
2017
28
Effects of traditional practices in the postpartum period on postpartum depression. ( 28850320 )
2017
29
Postpartum depression risk factors: A narrative review. ( 28852652 )
2017
30
Frequency of postpartum depression and its association with breastfeeding: A cross-sectional survey at immunization clinics in Islamabad, Pakistan. ( 28839296 )
2017
31
Psychological treatment is one of the several important components to the effective management of postpartum depression. ( 27934641 )
2017
32
Antidepressant-Like Effect of Selected Egyptian Cultivars of Flaxseed Oil on a Rodent Model of Postpartum Depression. ( 29333185 )
2017
33
Maternal touch in caregiving behavior of mothers with and without postpartum depression. ( 28946023 )
2017
34
Insomnia, postpartum depression and estradiol in women after delivery. ( 28791548 )
2017
35
Postpartum Depression Screening Tools: A Review. ( 29396166 )
2017
36
The perception of fairness in infant care and mothers' postpartum depression. ( 28866473 )
2017
37
A neuro-immune, neuro-oxidative and neuro-nitrosative model of prenatal and postpartum depression. ( 28941769 )
2017
38
The Relationship Between Women's Intention to Request a Labor Epidural Analgesia, Actually Delivering With Labor Epidural Analgesia, and Postpartum Depression at 6 Weeks: A Prospective Observational Study. ( 28930940 )
2017
39
Post-Up Study: Postpartum Depression Screening in Well-Child Care and Maternal Outcomes. ( 28882876 )
2017
40
Psychoeducational preventive treatment for women at risk of postpartum depression: study protocol for a randomized controlled trial, PROGEA. ( 28086766 )
2017
41
Telephone delivery of interpersonal psychotherapy by certified nurse-midwives may help reduce symptoms of postpartum depression. ( 27879285 )
2017
42
Adverse life events, psychiatric history, and biological predictors of postpartum depression in an ethnically diverse sample of postpartum women. ( 28950923 )
2017
43
Postpartum depression and associated factors after emergency peripartum hysterectomy. ( 28065954 )
2017
44
A closer look at the preventative effect of antidepressants in postpartum depression. ( 28050649 )
2017
45
Predictors of Postpartum Depression in Dubai, a Rapidly Growing Multicultural Society in the United Arab Emirates. ( 28953784 )
2017
46
Genetic variants of the kynurenine-3-monooxygenase and postpartum depressive symptoms after cesarean section in Chinese women. ( 28319697 )
2017
47
Negative caregiving representations and Postpartum Depression The Mediating Roles of Parenting Efficacy and Relationship Satisfaction. ( 28850324 )
2017
48
Positive postpartum depression screening practices and subsequent mental health treatment for low-income women in Western countries: a systematic literature review. ( 29450075 )
2017
49
Oxytocin receptor DNA methylation in postpartum depression. ( 27108164 )
2016
50
Screening for Postpartum Depression and Associated Factors Among Women in China: A Cross-Sectional Study. ( 27847483 )
2016

Variations for Postpartum Depression

Expression for Postpartum Depression

Search GEO for disease gene expression data for Postpartum Depression.

Pathways for Postpartum Depression

GO Terms for Postpartum Depression

Biological processes related to Postpartum Depression according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 response to drug GO:0042493 9.8 COMT CRH OXTR SLC6A4
2 positive regulation of cytosolic calcium ion concentration GO:0007204 9.7 CALCA ESR1 OXTR
3 response to estradiol GO:0032355 9.65 ESR1 OXTR SLC6A4
4 negative regulation of blood pressure GO:0045776 9.54 CALCA CRH
5 vasoconstriction GO:0042310 9.51 HTR1A SLC6A4
6 response to estrogen GO:0043627 9.5 COMT CRH ESR1
7 neurotransmitter catabolic process GO:0042135 9.46 COMT MAOA
8 catecholamine metabolic process GO:0006584 9.43 COMT MAOA
9 dopamine catabolic process GO:0042420 9.4 COMT MAOA
10 glucocorticoid biosynthetic process GO:0006704 9.37 CRH HSD11B1
11 sperm ejaculation GO:0042713 9.26 OXTR SLC6A4
12 female pregnancy GO:0007565 9.26 COMT CRH OXTR PRL
13 regulation of serotonin secretion GO:0014062 9.16 CRH HTR1A
14 response to pain GO:0048265 8.8 CALCA COMT CRH

Molecular functions related to Postpartum Depression according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.8 CALCA CRH PRL

Sources for Postpartum Depression

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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