Aliases & Classifications for Pouchitis

About this section
Sources:
39MESH via Orphanet, 49Novoseek, 53Orphanet, 67UMLS, 68UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Pouchitis:

Name: Pouchitis 53 49 67

Characteristics:

Orphanet epidemiological data:

53
pouchitis:
Prevalence: 1-5/10000 (Europe)

Classifications:



External Ids:

Orphanet53 ORPHA217067
MESH via Orphanet39 D019449
UMLS via Orphanet68 C0376620

Summaries for Pouchitis

About this section
Wikipedia:70 Pouchitis is inflammation of the ileal pouch (an artificial rectum surgically created out of ileal gut... more...

MalaCards based summary: Pouchitis is related to microscopic colitis and colitis, and has symptoms including peripancreatic fluid collection and post procedural diarrhea. An important gene associated with Pouchitis is NOD2 (Nucleotide Binding Oligomerization Domain Containing 2), and among its related pathways are Shigellosis and Legionellosis. Affiliated tissues include small intestine, liver and endothelial, and related mouse phenotypes are hematopoietic system and immune system.

Related Diseases for Pouchitis

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Diseases related to Pouchitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 144)
idRelated DiseaseScoreTop Affiliating Genes
1microscopic colitis28.1CXCL8, IL10, NOD2, TLR4
2colitis10.6
3ulcerative colitis10.6
4lacrimal system cancer10.3IL1RN, NOD2
5spondylohypoplasia, arthrogryposis and popliteal pterygium10.3NOD2, TLR4
6gastroduodenal crohn's disease10.3NOD2, TLR4
7benign lymphoepithelial lesion of salivary gland10.2LTF, TLR4
8senile cataract10.2IL10, IL1RN
9askin's tumor10.2IL10, IL1RN
10psoriasis susceptibility 110.2IL1RN, NOD2
11pernicious anemia10.1IL10, TLR4
12bartonellosis10.1IL10, TLR4
13binocular vision disease10.1IL10, TLR4
14corneal intraepithelial neoplasm10.1IL10, TLR4
15melioidosis10.1IL10, TLR4
16prostate calculus10.1CXCL8, NOD2
17oropharynx cancer10.1CXCL8, NOD2
18crohn's disease10.1
19uterine corpus endometrial stromal sarcoma10.0CXCL8, NOD2
20dengue disease10.0IL10, TLR4
21gastric ulcer10.0IL10, TLR4
22neurofibroma of the esophagus10.0CXCL8, IL1RN
23sternum lymphoma10.0IL10, IL1RN
24oral candidiasis10.0CXCL8, IL1RN
25variola minor10.0IL10, TLR4
26ileitis10.0
27tibialis tendinitis10.0CXCL8, IL1RN
28lymphangiectasia, intestinal10.0CXCL8, LTF
293-alpha hydroxyacyl-coa dehydrogenase deficiency10.0CXCL8, LTF
30subglottis neoplasm10.0CXCL8, TLR4
31meibomian cyst10.0CXCL8, TLR4
32gastric hemangioma10.0CXCL8, TLR4
33paraneoplastic polyneuropathy10.0CXCL8, TLR4
34arthritis10.0
35cytomegalovirus infection10.0
36sinusitis9.9CXCL8, IL1RN
37abducens nerve neoplasm9.9CXCL8, TLR4
38inner ear cancer9.9CXCL8, TLR4
39gallbladder lymphoma9.9CXCL8, TLR4
40partial of retinal vein occlusion9.9CXCL8, IL1RN
41tinea barbae9.9CXCL8, TLR4
42basidiobolomycosis9.9CXCL8, IL10
43gonadal disease9.9CXCL8, IL10
44acute interstitial pneumonia9.9CXCL8, IL10
45benign adult familial myoclonic epilepsy9.9CXCL8, IL10
46infancy electroclinical syndrome9.9CXCL8, IL10
47addison's disease9.9CXCL8, IL10
48marchiafava bignami disease9.9CXCL8, IL10
49burns9.9CXCL8, IL10
50gastric tubular adenocarcinoma9.9IL10, IL1RN

Graphical network of the top 20 diseases related to Pouchitis:



Diseases related to pouchitis

Symptoms for Pouchitis

About this section

UMLS symptoms related to Pouchitis:


peripancreatic fluid collection, post procedural diarrhea

Drugs & Therapeutics for Pouchitis

About this section

Drugs for Pouchitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 21)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
VedolizumabapprovedPhase 449943609-66-3
Synonyms:
 
Entyvio
2
Ciprofloxacinapproved, investigationalPhase 422985721-33-12764
Synonyms:
1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID
1-CYCLOPROPYL-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydroquinoline-3-carboxylic acid
1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperzinyl)-3-quinolinecarboxylic acid HCl H2O
1-Cyclopropyl-6-fluoro-1,4-dihydro-7-(1-piperazinyl)-4-oxo-3-quinoline carboxylic acid
1-Cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid
1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid
1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
1-Cyclopropyl-6-fluoro-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid
1-Cyclopropyl-6-fluoro-7-hexahydro-1-pyrazinyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
1-cyclopropyl-6-fluoro-7-hexahydro-1-pyrazinyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
17850_FLUKA
3-Quinolinecarboxylic acid,1,4-dihydro-1-cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)
33434_FLUKA
33434_RIEDEL
85721-33-1
AC-7613
AC1L1EEW
AKOS000269653
ARONIS020379
Alcon Cilox
BAS 06989041
BAY q 3939
BAY-Q-3939
BAYQ3939
BIDD:GT0205
BPBio1_000140
BRD-K04804440-311-02-3
BRN 3568352
BSPBio_000126
BSPBio_003344
Bacquinor
Baflox
Bay o 9867
Bay o 9867 (*Hydrochloride*)
Bay-09867
Baycip
Bernoflox
Bi-Cipro
Bio-0540
C05349
C17H18FN3O3
CAS-93107-08-5
CBMicro_048498
CCRIS 5241
CHEBI:100241
CHEMBL8
CID2764
CIPRO IN DEXTROSE 5% IN PLASTIC CONTAINER
CIPRO IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
CPF
CPFX
CRL-1605 & Ciprofloxacin
Ciflox
Cifloxin
Cilab
Ciloxan
Ciloxan (*Hydrochloride*)
Ciplus
Ciprecu
Ciprinol
Cipro
Cipro (*Hydrochloride*)
Cipro (TN)
Cipro I.V.
Cipro IV
Cipro XL
Cipro XR
Ciprobay
Ciprobay Uro
Ciprocinol
Ciprodar
Ciproflox
Ciprofloxacin
Ciprofloxacin (JAN/USP/INN)
Ciprofloxacin HCl
Ciprofloxacin Hydrchloride
Ciprofloxacin [USAN:INN:BAN]
Ciprofloxacin dihydrochloride
Ciprofloxacin hydrochloride
Ciprofloxacin monohydrochloride
Ciprofloxacina
Ciprofloxacine
Ciprofloxacine [INN-French]
Ciprofloxacino
 
Ciprofloxacino [INN-Spanish]
Ciprofloxacinum
Ciprofloxacinum [INN-Latin]
Ciprogis
Ciprolin
Ciprolon
Cipromycin
Ciproquinol
Ciprowin
Ciproxan
Ciproxin
Ciproxina
Ciproxine
Ciriax
Citopcin
Cixan
Corsacin
Cycin
Cyprobay
D00186
DB00537
DivK1c_000095
Eni
Fimoflox
Flociprin
Floxin
HMS1922E18
HMS2090O07
HMS2093I03
HMS500E17
HSDB 6987
IDI1_000095
Ipiflox
Italnik
KBio1_000095
KBio2_000642
KBio2_003210
KBio2_005778
KBio3_002846
KBioGR_001567
KBioSS_000642
LS-141563
Liposomal-ciprofloxacin
Loxan
MLS001336035
MolPort-000-819-654
NCGC00016959-01
NCGC00095058-01
NCGC00095058-02
NCGC00178128-01
NINDS_000095
NSC620634
Ocuflox
Oprea1_008239
Oprea1_313572
Prestwick0_000113
Prestwick1_000113
Prestwick2_000113
Prestwick3_000113
Probiox
Proflaxin
Proflox
Proksi 250
Proksi 500
Proquin XR
Quinolid
Quintor
Rancif
Roxytal
SMP1_000125
SMR000471901
SPBio_001474
SPBio_002065
SPECTRUM1503614
STK021082
Septicide
Sophixin Ofteno
Spectrum2_001567
Spectrum3_001872
Spectrum4_000874
Spectrum5_001089
Spectrum_000162
Spitacin
Superocin
UNII-5E8K9I0O4U
Unex
Velomonit
Zumaflox
ciprofloxacin
nchembio820-comp1
3
Certolizumab pegolapprovedPhase 4122428863-50-7
Synonyms:
428863-50-7
CDP870
Certolizumab pegol
 
Certolizumab pegol (USAN/INN)
Certolizumab pegol (genetical recombination)
Certolizumab pegol (genetical recombination) (JAN)
D03441
cimzia
4Antirheumatic AgentsPhase 4, Phase 310627
5Anti-Bacterial AgentsPhase 4, Phase 3, Phase 1, Phase 210884
6Topoisomerase InhibitorsPhase 44945
7Immunosuppressive AgentsPhase 4, Phase 312770
8Gastrointestinal AgentsPhase 4, Phase 38109
9Cytochrome P-450 CYP1A2 InhibitorsPhase 4553
10Anti-Infective AgentsPhase 4, Phase 3, Phase 1, Phase 221402
11Cytochrome P-450 Enzyme InhibitorsPhase 43822
12
AdalimumabapprovedPhase 3478331731-18-116219006
Synonyms:
331731-18-1
Adalimumab
Adalimumab (USAN/INN)
Adalimumab (genetical recombination)
 
Adalimumab (genetical recombination) (JAN)
D02597
Humira
Humira (TN)
Humira Pen
Ig gamma-1 chain C region
13Anti-Inflammatory AgentsPhase 310355
14Antibiotics, AntitubercularPhase 3, Phase 1, Phase 26972
15
AlicaforsenPhase 35185229-68-916197724
Synonyms:
185229-68-9
Alicaforsen
Alicaforsen [INN]
DNA, d((R)-P-thio)(G-C-C-A-A-G-C-T-G-G-C-A-T-C-C-G-T-C-A)
 
Deoxyribonucleic acid, d((R)-P-thio)(G-C-C-C-A-A-G-C-T-G-G-C-A-T-C-C-G-T-C-A)
ISIS 2302
ISIS-2302
Intercellular adhesion molecule-1 antisense oligodeoxynucleotide
LS-63362
16
MentholapprovedPhase 223532216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Caswell No. 540
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
DivK1c_000820
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
FEMA No. 2665
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
HMS1922G13
HMS2092L14
HMS502I22
 
HSDB 5662
HSDB 593
Headache crystals
Hexahydrothymol
I06-1216
I14-7371
IDI1_000820
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Menthomenthol
Menthyl alcohol
MolPort-000-849-729
MolPort-001-793-392
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Neoisomenthol
Peppermint camphor
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
ZINC01482164
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol
17
Clotrimazoleapproved, vet_approvedPhase 1, Phase 23523593-75-12812
Synonyms:
(Chlorotrityl)imidazole
1-((2-Chlorophenyl)diphenylmethyl)-1H-imidazole
1-(O-Chloro-alpha,alpha-diphenylbenzyl)imidazole
1-(O-Chlorotrityl)imidazole
1-(alpha-(2-Chlorophenyl)benzhydryl)imidazole
1-(o-Chloro-α,α-diphenylbenzyl)imidazole
1-(o-Chlorotrityl)imidazole
1-(α-(2-Chlorophenyl)benzhydryl)imidazole
117829-71-7
23593-75-1
33894_FLUKA
33894_RIEDEL
3ACDFDF8-38E3-4368-85D0-BDF8AE1E6591
AB00051951
AC-279
AC1L1EIW
B 5097
BAY 5097
BAY b 5097
BAY b5097
BAY-5097
BAYb 5097
BIDD:GT0450
BIDD:PXR0036
BPBio1_000126
BRN 0622318
BSPBio_000114
BSPBio_002057
Bay b 9057
Bay-B 5097
Bayer Brand 1 of Clotrimazole
Bayer Brand 2 of Clotrimazole
Bio-0442
C 6019
C06922
C22H17ClN2
C6019_SIGMA
CAS-23593-75-1
CCRIS 6245
CHEBI:3764
CHEMBL104
CID2812
CPD-8926
CPD000058306
Canesten
Canesten 1-Day Cream Combi-Pak
Canesten 1-Day Therapy
Canesten 3-Day Therapy
Canesten 6-Day Therapy
Canesten Combi-Pak 1-Day Therapy
Canesten Combi-Pak 3-Day Therapy
Canesten Cream
Canesten Solution
Canestene
Canestine
Canifug
Chlotrimazole
Cimitidine
Clomatin
Clotrimaderm
Clotrimaderm Cream
Clotrimazol
Clotrimazol [INN-Spanish]
Clotrimazole
Clotrimazole (JP15/USP/INN)
Clotrimazole Schering Brand
Clotrimazole [USAN:INN:BAN:JAN]
Clotrimazolum
Clotrimazolum [INN-Latin]
Cutistad
D00282
D003022
DB00257
DRG-0072
Desamix F
DivK1c_000665
EINECS 245-764-8
EU-0100315
Empecid
Esparol
FB 5097
FB b 5097
Fem Care
FemCare
Gino-Lotremine
Gyne lotrimin
Gyne-Lotrimin
Gyne-Lotrimin 3
Gyne-Lotrimin 3 Combination Pack
Gyne-Lotrimin Combination Pack
Gyne-Lotrimin3
Gyne-Lotrimin3 Combination Pack
Gyne-lotrimin
Gynix
HMS1568F16
HMS1920O21
HMS2051E11
HMS2091G10
HMS502B07
HSDB 3266
I01-3474
IDI1_000665
 
KBio1_000665
KBio2_001823
KBio2_004391
KBio2_006959
KBio3_001277
KBioGR_000850
KBioSS_001823
Kanesten
Klotrimazole
LS-78271
Lopac-C-6019
Lopac0_000315
Lotrimax
Lotrimin
Lotrimin (TN)
Lotrimin (tn)
Lotrimin AF
Lotrimin AF Cream
Lotrimin AF Jock-Itch Cream
Lotrimin AF Lotion
Lotrimin AF Solution
Lotrimin Af
Lotrimin Cream
Lotrimin Lotion
Lotrimin Solution
Lotrisone
MLS000028502
MLS000758243
MLS001423972
MolPort-002-557-756
Mono-baycuten
Monobaycuten
Mycelax
Mycelex
Mycelex (TN)
Mycelex (tn)
Mycelex 7
Mycelex Cream
Mycelex G
Mycelex OTC
Mycelex Solution
Mycelex Troches
Mycelex Twin Pack
Mycelex-7
Mycelex-7 Combination Pack
Mycelex-G
Mycelex: MycosporinRimazole
Myclo Cream
Myclo Solution
Myclo Spray Solution
Myclo-Gyne
Mycofug
Mycosporin
Mykosporin
NCGC00015251-01
NCGC00015251-02
NCGC00015251-03
NCGC00015251-09
NCGC00093761-01
NCGC00093761-02
NCGC00093761-03
NCGC00093761-04
NCGC00093761-05
NCGC00093761-06
NCIMech_000609
NINDS_000665
NSC 257473
NSC257473
Nalbix
Neo-Zol Cream
Otomax
Pan-Fungex
Pedisafe
Prestwick0_000267
Prestwick1_000267
Prestwick2_000267
Prestwick3_000267
Prestwick_120
QTL1_000024
Rimazole
S1606_Selleck
SAM001247056
SMR000058306
SPBio_000176
SPBio_002333
SPECTRUM1500200
STK700023
Schering Brand of Clotrimazole
Spectrum2_000128
Spectrum3_000359
Spectrum4_000295
Spectrum5_000781
Spectrum_001343
Stiemazol
Tibatin
Trimysten
Trivagizole 3
UNII-G07GZ97H65
Veltrim
ZINC03807804
clotrimazole
clotrimeizol
nchembio.65-comp9
nchembio790-comp30
18Antitubercular AgentsPhase 21272
19Defensins7
20Immunoglobulins6045
21Antibodies6045

Interventional clinical trials:

(show all 20)
idNameStatusNCT IDPhase
1VSL#3 Treatment in Children With Crohn's DiseaseUnknown statusNCT00367705Phase 4
2Phase 4 Study to Evaluate the Efficacy and Safety of Vedolizumab in the Treatment of Chronic PouchitisRecruitingNCT02790138Phase 4
3EUS Evaluation of Perianal and Peri-rectal Fistulizing Crohn's Disease With CERTOLIZUMAB TreatmentTerminatedNCT01582568Phase 4
4Adalimumab in the Treatment of Chronic PouchitisCompletedNCT01670240Phase 3
5Clinical Approaches to Ileal Pouch DysfunctionCompletedNCT00293553Phase 3
6Randomized Study of Topical Alicaforsen Enema in Antibiotic Refractory PouchitisRecruitingNCT02525523Phase 3
7To Determine the Effect of Honey Enema in the Treatment of Patients With Acute PouchitisUnknown statusNCT02201186Phase 2
8Safety and Efficacy of AST-120 in the Treatment of PouchitisCompletedNCT00583076Phase 2
9FMT in Ulcerative Colitis-Associated PouchitisRecruitingNCT02049502Phase 2
10Safety and Efficacy of Fecal Microbiome Transplantation (FMT) in the Treatment of Antibiotic Dependent Pouchitis (ADP)Not yet recruitingNCT02782325Phase 1, Phase 2
11Clotrimazole Enemas for Pouchitis in Children and AdultsSuspendedNCT00061282Phase 1, Phase 2
12Safety and Efficacy of AST-120 in the Treatment of Antibiotic-Refractory PouchitisTerminatedNCT00583531Phase 2
13Study of Sc-FOS for Pouchitis PreventionRecruitingNCT02203955Phase 1
14The Interaction Between Intestinal Microbiota, Innate Defense and Epithelial Integrity in the Development of PouchitisUnknown statusNCT01202396
15Clinical Outcome After Close Rectal Ileo Pouch Anal Anastomosis for Colitis Ulcerosa(CU)Unknown statusNCT01111708
16Surgical Reconstruction in Ulcerative Colitis With Primary Sclerosing CholangitisCompletedNCT01798953
17Characterization of Disease Related Changes in Inflammatory Bowel Disease Using Fecal Metabolite ProfilingCompletedNCT01666717
18Fecal Microbiota Transplant (FMT) for PouchitisRecruitingNCT02428361Early Phase 1
19Nutritional Impact of Serum-Derived Bovine Immunoglobulin Protein Isolate in Subjects With IPAARecruitingNCT02828410
20MRI in Normal Ileal Pouches, and a Feasibility Study of Dynamic MRI Enema and Defaecating MRI PouchographyNot yet recruitingNCT02925260

Search NIH Clinical Center for Pouchitis

Genetic Tests for Pouchitis

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Anatomical Context for Pouchitis

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MalaCards organs/tissues related to Pouchitis:

35
Small intestine, Liver, Endothelial, Neutrophil, T cells, Prostate, Colon

Animal Models for Pouchitis or affiliated genes

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MGI Mouse Phenotypes related to Pouchitis:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053978.4IL10, IL1RN, LTF, NOD2, TLR4
2MP:00053877.6IL10, IL1RN, LTF, NOD2, TLR4

Publications for Pouchitis

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Articles related to Pouchitis:

(show top 50)    (show all 392)
idTitleAuthorsYear
1
The prevalence of chronic peri-pouch sepsis in patients treated for antibiotic-dependent or refractory primary idiopathic pouchitis. (27688067)
2016
2
Methodological Quality Assessment of Meta-Analyses and Systematic Reviews of Probiotics in Inflammatory Bowel Disease and Pouchitis. (28005973)
2016
3
Predictors of Pouchitis After Ileal Pouch-Anal Anastomosis in Children. (27243421)
2016
4
Fecal microbiota in pouchitis and ulcerative colitis. (27833384)
2016
5
DOP086. Enteric micriobiota alterations in patients with a normal ileal pouch may be predictive of pouchitis. (25718302)
2015
6
Variable alterations of the microbiota, without metabolic or immunological change, following faecal microbiota transplantation in patients with chronic pouchitis. (26264409)
2015
7
A treatment strategy for preventing pouchitis as a postoperative complication of ulcerative colitis: the significance of the management of cuffitis. (25022954)
2014
8
The association between autoimmunity and pouchitis. (24374879)
2014
9
Cytomegalovirus pouchitis in a patient with Crohn's disease. (25035450)
2014
10
Infliximab for the treatment of pouchitis. (24303499)
2013
11
Meta-analysis: serological markers and the risk of acute and chronic pouchitis. (23480145)
2013
12
Characteristics of extremely early-onset pouchitis after proctocolectomy with ileal pouch-anal anastomosis. (23254315)
2013
13
Commentary: The effects of probiotics on barrier function and mucosal pouch microbiota during maintenance treatment for severe pouchitis in patients with ulcerative colitis. (24206372)
2013
14
Stricture of ileo-anal J pouch anastomosis increased the intensity of pouchitis in an experimental rat model. (23018348)
2012
15
An open study of maintenance antibiotic therapy for chronic antibiotic-dependent pouchitis: efficacy, complications and outcome. (20041929)
2011
16
Pharmacotherapy for acute pouchitis. (21775695)
2011
17
Pouchitis and pouch dysfunction. (19944799)
2010
18
Secondary pouchitis: those with identifiable etiopathogenetic or triggering factors. (19755972)
2010
19
Re: Adenocarcinoma arising in a background of chronic atrophic pouchitis in an ileoanal pouch for ulcerative colitis. (19302532)
2009
20
Predictors of pouchitis after ileal pouch-anal anastomosis: a retrospective review. (19273980)
2009
21
Leukocytapheresis for the treatment of active pouchitis: a pilot study. (18648745)
2008
22
On the benefit of probiotics in the management of pouchitis in patients underwent ileal pouch anal anastomosis: a meta-analysis of controlled clinical trials. (17940902)
2008
23
Pouchitis and pre-pouch ileitis developed after restorative proctocolectomy for ulcerative colitis: a case report. (17278237)
2007
24
Chronic pouchitis after ileal pouch-anal anastomosis for ulcerative colitis: effect on quality of life. (16627228)
2006
25
Adenocarcinoma of the ileoanal pouch for ulcerative colitis--a complication of severe chronic atrophic pouchitis? (16365680)
2006
26
Inflammatory bowel disease: a new combination therapy for pouchitis. (15976743)
2005
27
Fecal pyruvate kinase (M2-PK): a new predictor for inflammation and severity of pouchitis. (16293562)
2005
28
Diagnostic difficulties in pouchitis--experience from a single institution. (15469209)
2004
29
Human lymphocyte stimulation with pouchitis flora is greater than with flora from a healthy pouch but is suppressed by metronidazole. (15542518)
2004
30
Histologic predictors of pouchitis in patients with chronic ulcerative colitis. (15252305)
2004
31
Prevention is the best defense: surgical prophylaxis of pouchitis. (14753221)
2004
32
Diagnosis and management of pouchitis. (12761722)
2003
33
Long-term follow-up after ileoanal pouch procedure: algorithm for diagnosis, classification, and management of pouchitis. (11330575)
2001
34
Increase in cyclooxygenase-2 and nitric oxide-synthase-2 mRNAs in pouchitis without modification of inducible isoenzyme heme-oxygenase-1. (11467644)
2001
35
Association of decreased perfusion of the ileoanal pouch mucosa with early postoperative pouchitis and local septic complications. (11585503)
2001
36
The interleukin 1 receptor antagonist gene allele 2 as a predictor of pouchitis following colectomy and IPAA in ulcerative colitis. (11606494)
2001
37
Colectomy and ileal pouch. Transport and barrier in pouchitis. (11193590)
2000
38
Pouchitis: pathogenesis, diagnosis, and management. (8792143)
1996
39
Severe pouchitis successfully treated with short-chain fatty acids. (8769932)
1996
40
Antineutrophil cytoplasmic antibody correlates with chronic pouchitis after ileal pouch-anal anastomosis. (7733080)
1995
41
p-ANCA and development of pouchitis in ulcerative colitis patients after proctocolectomy and ileoanal pouch anastomosis. (7916418)
1994
42
Pouchitis: result of microbial imbalance? (8200561)
1994
43
Pouchitis--recurrence of the inflammatory bowel disease? (8307476)
1994
44
Topical metronidazole treatment in pouchitis. (8036463)
1994
45
Pouchitis following ileal pouch-anal anastomosis: definition, pathogenesis, and treatment. (7958702)
1994
46
The pull-through procedure: technical factors in influencing outcome, with emphasis on pouchitis. (8211701)
1993
47
Cyclosporin A retention enemas in refractory distal ulcerative colitis and 'pouchitis'. (8210986)
1993
48
Results of pouch surgery after ileo-anal anastomosis: the implications of pouchitis. (1462623)
1992
49
The pelvic ileal reservoir: pathology and pouchitis. (2172847)
1990
50
Pouchitis. (3058838)
1988

Variations for Pouchitis

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Expression for genes affiliated with Pouchitis

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Search GEO for disease gene expression data for Pouchitis.

Pathways for genes affiliated with Pouchitis

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GO Terms for genes affiliated with Pouchitis

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Cellular components related to Pouchitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056158.1CXCL8, IL10, IL1RN, LTF

Biological processes related to Pouchitis according to GeneCards Suite gene sharing:

(show all 19)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of stress-activated MAPK cascadeGO:003287410.2NOD2, TLR4
2positive regulation of nitric-oxide synthase biosynthetic processGO:005177010.1NOD2, TLR4
3positive regulation of interleukin-10 productionGO:003273310.1NOD2, TLR4
4positive regulation of tumor necrosis factor productionGO:003276010.1NOD2, TLR4
5positive regulation of JNK cascadeGO:004633010.1NOD2, TLR4
6positive regulation of interleukin-6 productionGO:00327559.8NOD2, TLR4
7negative regulation of interferon-gamma productionGO:00326899.7IL10, TLR4
8negative regulation of tumor necrosis factor productionGO:00327209.7IL10, TLR4
9positive regulation of MHC class II biosynthetic processGO:00453489.7IL10, TLR4
10response to molecule of bacterial originGO:00022379.6CXCL8, IL10
11negative regulation of interleukin-6 productionGO:00327159.6IL10, TLR4
12positive regulation of I-kappaB kinase/NF-kappaB signalingGO:00431239.6LTF, NOD2, TLR4
13positive regulation of interleukin-8 productionGO:00327579.5NOD2, TLR4
14regulation of inflammatory responseGO:00507279.5NOD2, TLR4
15positive regulation of NF-kappaB transcription factor activityGO:00510929.4LTF, NOD2, TLR4
16cellular response to lipopolysaccharideGO:00712229.1CXCL8, IL10, TLR4
17defense response to bacteriumGO:00427428.9IL10, NOD2, TLR4
18inflammatory responseGO:00069548.5CXCL8, IL10, TLR4
19immune responseGO:00069557.7CXCL8, IL10, IL1RN, TLR4

Sources for Pouchitis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet