MCID: PRD006
MIFTS: 62

Prader-Willi Syndrome malady

Genetic diseases, Rare diseases, Neuronal diseases, Reproductive diseases, Endocrine diseases, Fetal diseases categories

Aliases & Classifications for Prader-Willi Syndrome

About this section
Sources:
49OMIM, 10Disease Ontology, 11diseasecard, 68Wikipedia, 21GeneReviews, 45NIH Rare Diseases, 22GeneTests, 23Genetics Home Reference, 47Novoseek, 12DISEASES, 51Orphanet, 24GTR, 35MedlinePlus, 36MeSH, 59SNOMED-CT, 42NCIt, 65UMLS, 29ICD9CM, 66UMLS via Orphanet, 28ICD10 via Orphanet, 37MESH via Orphanet
See all sources

Aliases & Descriptions for Prader-Willi Syndrome:

Name: Prader-Willi Syndrome 49 10 11 68 21 45 23 47 12 51 35 36
Prader-Labhart-Willi Syndrome 68 21 45 22 23 51
Willi-Prader Syndrome 45 22 23 51 24
 
Pws 68 21 45 22 23
Prader Willi Syndrome 10


Classifications:



Characteristics (Orphanet epidemiological data):

51
prader-willi syndrome:
Inheritance: Not applicable; Prevalence: 1-9/100000 (Europe); Age of onset: Antenatal,Neonatal; Age of death: normal life expectancy


External Ids:

OMIM49 176270
Disease Ontology10 DOID:11983
NCIt42 C75463
ICD9CM29 759.81
MeSH36 D011218
SNOMED-CT59 89392001, 205794007
Orphanet51 739
UMLS via Orphanet66 C0032897
ICD10 via Orphanet28 Q87.1
MESH via Orphanet37 D011218

Summaries for Prader-Willi Syndrome

About this section
MedlinePlus:35 Prader-willi syndrome (pws) is a rare genetic disorder. it causes poor muscle tone, low levels of sex hormones and a constant feeling of hunger. the part of the brain that controls feelings of fullness or hunger does not work properly in people with pws. they overeat, leading to obesity. babies with pws are usually floppy, with poor muscle tone, and have trouble sucking. boys may have undescended testicles. later, other signs appear. these include short stature poor motor skills weight gain underdeveloped sex organs mild intellectual and learning disabilities there is no cure for pws. growth hormone, exercise, and dietary supervision can help build muscle mass and control weight. other treatments may include sex hormones and behavior therapy. most people with pws will need specialized care and supervision throughout their lives. nih: national institute of child health and human development

MalaCards based summary: Prader-Willi Syndrome, also known as prader-labhart-willi syndrome, is related to obesity and sleep disorder, and has symptoms including hypogonadotrophic hypogonadism, delayed speech and language development and infertility. An important gene associated with Prader-Willi Syndrome is NDN (Necdin, Melanoma Antigen (MAGE) Family Member), and among its related pathways are Synaptic Neurotransmission: GABAergic Inhibition and Adipogenesis. Affiliated tissues include brain, testes and skin, and related mouse phenotypes are adipose tissue and endocrine/exocrine gland.

NIH Rare Diseases:45 Prader-willi syndrome (pws) is a genetic condition that affects many parts of the body. infants with pws have severe hypotonia (low muscle tone), feeding difficulties, and slow growth. in later infancy or early childhood, affected children typically begin to eat excessively and become obese. other signs and symptoms often include short stature, hypogonadism, developmental delays, cognitive impairment, and distinctive behavioral characteristics such as temper tantrums, stubbornness, and obsessive-compulsive tendencies. pws is caused by missing or non-working genes on chromosome 15. most cases are not inherited and occur randomly. rarely, a genetic change responsible for pws can be inherited. in general, management of this condition depends on the affected person's age and symptoms. last updated: 9/30/2015

Genetics Home Reference:23 Prader-Willi syndrome is a complex genetic condition that affects many parts of the body. In infancy, this condition is characterized by weak muscle tone (hypotonia), feeding difficulties, poor growth, and delayed development. Beginning in childhood, affected individuals develop an insatiable appetite, which leads to chronic overeating (hyperphagia) and obesity. Some people with Prader-Willi syndrome, particularly those with obesity, also develop type 2 diabetes mellitus (the most common form of diabetes).

OMIM:49 Prader-Willi syndrome is characterized by diminished fetal activity, obesity, muscular hypotonia, mental retardation,... (176270) more...

Wikipedia:68 Prader–Willi syndrome (/ˈprɑːdər ˈvɪli/; abbreviated PWS) is a rare genetic disorder in which... more...

GeneReviews summary for pws

Related Diseases for Prader-Willi Syndrome

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Diseases in the Prader-Willi Syndrome family:

Prader-Willi Syndrome Due to Paternal Deletion of 15q11q13 Type 1 Prader-Willi Syndrome Due to Paternal Deletion of 15q11q13 Type 2
Prader-Willi Syndrome Due to Translocation Prader-Willi Syndrome Due to Imprinting Mutation
Prader-Willi Syndrome Due to Point Mutation Prader-Willi-Like Syndrome Due to Point Mutation
Prader-Willi Syndrome Due to Paternal 15q11q13 Deletion Prader-Willi Syndrome Due to Maternal Uniparental Disomy of Chromosome 15

Diseases related to Prader-Willi Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 273)
idRelated DiseaseScoreTop Affiliating Genes
1obesity31.5GH1, GHRL, IGF1, LEP, MAGEL2, PYY
2sleep disorder31.3GHRL, IGF1, LEP
3prader-willi syndrome due to paternal deletion of 15q11q13 type 230.9MAGEL2, NDN, OCA2, SNRPN
4prader-willi syndrome due to translocation30.9MAGEL2, NDN, OCA2, SNRPN
5hypersensitivity reaction type ii disease30.3GH1, IGF1
6diabetes mellitus, noninsulin-dependent30.1GH1, GHRL, IGF1, LEP, PYY
7angelman syndrome29.3GABRA5, GABRB3, GH1, GHRL, IGF1, IPW
8intellectual disability11.0
9chromosomal disease11.0
10congenital nervous system abnormality11.0
11nutritional deficiency disease11.0
12overnutrition11.0
13child syndrome11.0
14kid syndrome11.0
15adult syndrome10.9
16hypotonia10.8
17morbid obesity10.8
18scoliosis10.8
19c syndrome10.7
20mass syndrome10.7
21hypogonadism10.7
22developmental disabilities10.7
23growth hormone deficiency10.7
24exfoliation syndrome10.6
25neuronitis10.6
26peeling skin syndrome10.6
27eating disorder10.6
28sleep apnea10.6
29insulin-like growth factor i10.6
30good syndrome10.6
31autism spectrum disorder10.6
32wells syndrome10.6
33obsessive-compulsive disorder10.6
34peeling skin syndrome 210.6
35obstructive sleep apnea10.6
36anemia, sideroblastic, pyridoxine-refractory, autosomal recessive10.5
37peeling skin syndrome 110.5
38miller syndrome10.5
39skin disease10.5
40down syndrome10.5
41adjustment disorder10.5
42bone structure disease10.5
43hypothalamic disease10.5
44thyroiditis10.5
45acdc10.5
46brown syndrome10.5
47rare intellectual disability without developmental anomaly10.5
48hypersomnia10.5
49peeling skin syndrome 310.5
50n syndrome10.5

Graphical network of the top 20 diseases related to Prader-Willi Syndrome:



Diseases related to prader-willi syndrome

Symptoms for Prader-Willi Syndrome

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Symptoms by clinical synopsis from OMIM:

176270

Clinical features from OMIM:

176270

Symptoms:

 51 (show all 29)
  • microcephaly
  • downslanted palpebral fissures/anti-mongoloid slanting palpebral fissures
  • strabismus/squint
  • telecanthus/canthal dystopy
  • downturned mouth
  • high vaulted/narrow palate
  • enamel anomaly
  • ear cartilage deficiency
  • scoliosis
  • short hand/brachydactyly
  • simian crease/transverse/unique palmar crease
  • clinodactyly of fifth finger
  • abnormal implantation of hair
  • renal glomerular defect/glomerulopathy
  • micropenis/small penis/agenesis
  • undescended/ectopic testes/cryptorchidia/unfixed testes
  • insulin-dependent/type 1 diabetes
  • late puberty/hypogonadism/hypogenitalism
  • ataxia/incoordination/trouble of the equilibrium
  • hypotonia
  • seizures/epilepsy/absences/spasms/status epilepticus
  • intellectual deficit/mental/psychomotor retardation/learning disability
  • psychic/behavioural troubles
  • delayed bone age
  • total/partial trisomy/duplication
  • insterstitial/subtelomeric microdeletion/deletion
  • generalized obesity
  • short stature/dwarfism/nanism
  • intrauterine growth retardation

HPO human phenotypes related to Prader-Willi Syndrome:

(show all 100)
id Description Frequency HPO Source Accession
1 hypogonadotrophic hypogonadism hallmark (90%) HP:0000044
2 delayed speech and language development hallmark (90%) HP:0000750
3 infertility hallmark (90%) HP:0000789
4 growth hormone deficiency hallmark (90%) HP:0000824
5 global developmental delay hallmark (90%) HP:0001263
6 motor delay hallmark (90%) HP:0001270
7 generalized hypotonia hallmark (90%) HP:0001290
8 specific learning disability hallmark (90%) HP:0001328
9 obesity hallmark (90%) HP:0001513
10 failure to thrive in infancy hallmark (90%) HP:0001531
11 short foot hallmark (90%) HP:0001773
12 poor suck hallmark (90%) HP:0002033
13 polyphagia hallmark (90%) HP:0002591
14 short palm hallmark (90%) HP:0004279
15 narrow palm hallmark (90%) HP:0004283
16 short stature hallmark (90%) HP:0004322
17 cryptorchidism 85% HP:0000028
18 attention deficit hyperactivity disorder common (75%) HP:0007018
19 scrotal hypoplasia 69% HP:0000046
20 adrenal insufficiency 60% HP:0000846
21 primary amenorrhea 56% HP:0000786
22 micropenis typical (50%) HP:0000054
23 clitoral hypoplasia typical (50%) HP:0000060
24 hypoplastic labia minora typical (50%) HP:0000064
25 thin upper lip vermilion typical (50%) HP:0000219
26 narrow forehead typical (50%) HP:0000341
27 narrow nasal bridge typical (50%) HP:0000446
28 delayed puberty typical (50%) HP:0000823
29 cutaneous photosensitivity typical (50%) HP:0000992
30 nasal speech typical (50%) HP:0001611
31 recurrent respiratory infections typical (50%) HP:0002205
32 scoliosis typical (50%) HP:0002650
33 downturned corners of mouth typical (50%) HP:0002714
34 kyphosis typical (50%) HP:0002808
35 decreased muscle mass typical (50%) HP:0003199
36 almond-shaped palpebral fissure typical (50%) HP:0007874
37 sleep apnea typical (50%) HP:0010535
38 cryptorchidism typical (50%) HP:0000028
39 abnormality of the palate typical (50%) HP:0000174
40 microcephaly typical (50%) HP:0000252
41 strabismus typical (50%) HP:0000486
42 downslanted palpebral fissures typical (50%) HP:0000494
43 telecanthus typical (50%) HP:0000506
44 abnormality of dental enamel typical (50%) HP:0000682
45 behavioral abnormality typical (50%) HP:0000708
46 single transverse palmar crease typical (50%) HP:0000954
47 brachydactyly syndrome typical (50%) HP:0001156
48 seizures typical (50%) HP:0001250
49 muscular hypotonia typical (50%) HP:0001252
50 intrauterine growth retardation typical (50%) HP:0001511
51 obesity typical (50%) HP:0001513
52 incoordination typical (50%) HP:0002311
53 delayed skeletal maturation typical (50%) HP:0002750
54 abnormality of chromosome segregation typical (50%) HP:0002916
55 clinodactyly of the 5th finger typical (50%) HP:0004209
56 short stature typical (50%) HP:0004322
57 hypoplasia of penis typical (50%) HP:0008736
58 cognitive impairment typical (50%) HP:0100543
59 type i diabetes mellitus typical (50%) HP:0100651
60 hypoplasia of the ear cartilage typical (50%) HP:0100720
61 glomerulopathy typical (50%) HP:0100820
62 oligomenorrhea frequent (33%) HP:0000876
63 hypopigmentation of the skin frequent (33%) HP:0001010
64 ventriculomegaly frequent (33%) HP:0002119
65 hypopigmentation of hair frequent (33%) HP:0005599
66 impaired pain sensation frequent (33%) HP:0007328
67 iris hypopigmentation frequent (33%) HP:0007730
68 type ii diabetes mellitus 25% HP:0005978
69 autism 19% HP:0000717
70 psychosis 15% HP:0000709
71 seizures 15% HP:0001250
72 hip dysplasia 10% HP:0001385
73 myopia occasional (7.5%) HP:0000545
74 esotropia occasional (7.5%) HP:0000565
75 upslanted palpebral fissure occasional (7.5%) HP:0000582
76 carious teeth occasional (7.5%) HP:0000670
77 osteopenia occasional (7.5%) HP:0000938
78 osteoporosis occasional (7.5%) HP:0000939
79 syndactyly occasional (7.5%) HP:0001159
80 frontal upsweep of hair occasional (7.5%) HP:0002236
81 temperature instability occasional (7.5%) HP:0005968
82 poor fine motor coordination occasional (7.5%) HP:0007010
83 radial deviation of finger occasional (7.5%) HP:0009466
84 precocious puberty 4% HP:0000826
85 hypogonadism HP:0000135
86 intellectual disability HP:0001249
87 muscular hypotonia HP:0001252
88 truncal obesity HP:0001956
89 feeding difficulties in infancy HP:0008872
90 thin upper lip vermilion HP:0000219
91 dolichocephaly HP:0000268
92 hypermetropia HP:0000540
93 hyperinsulinemia HP:0000842
94 decreased fetal movement HP:0001558
95 hypoventilation HP:0002791
96 sporadic HP:0003745
97 poor gross motor coordination HP:0007015
98 generalized hypopigmentation HP:0007513
99 abdominal obesity HP:0012743
100 clinodactyly HP:0030084

Drugs & Therapeutics for Prader-Willi Syndrome

About this section

Drugs for Prader-Willi Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 26)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
LiraglutideapprovedPhase 4, Phase 3257204656-20-2
Synonyms:
204656-20-2
Arg34Lys26-(N-ε-(γ-Glu(N-α-hexadecanoyl)))-GLP-1[7-37]
C439759
Liraglutida
Liraglutida [INN-Spanish]
Liraglutide
Liraglutide [USAN:INN]
Liraglutidum
Liraglutidum [INN-Latin]
N26-(Hexadecanoyl-gamma-glutamyle)-(34-arginine)GLP-1-(7-37)-peptide
N26-(Hexadecanoyl-gamma-glutamyle)-(34-arginine)glucagon-like-peptide-1-(7-37)-peptide
 
NN 2211
NN-2211
NN2211
NNC 90-1170
N²⁶-(N-Hexadecanoyl-L-gamma-glutamyl)-[34-L-arginine]glucagon-like peptide 1-(7-37)-peptide
N²⁶-(hexadecanoyl-gamma-glutamyle)-[34-arginine]GLP-1-(7-37)-peptide
Saxenda
UNII-839I73S42A
Victoza
nn 2211
nn2211
victoza
2
Octreotideapproved, investigationalPhase 319183150-76-9383414, 6400441
Synonyms:
(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-19-[[(2R)-2-amino-3-phenylpropanoyl]amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
10-(4-Aminobutyl)-19-((2-amino-3-phenylpropanoyl)amino)-16-benzyl-7-(1-hydroxyethyl)-N-(2-hydroxy-1-(hydroxymethyl)propyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaa
10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-(1,3-dihydroxybutan-2-yl)-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
79517-01-4 (acetate salt)
83150-76-9
AC1L1GVU
AC1L8LCD
AC1L9M4X
C07306
C5H12O2.C4H10
CHEBI:427278
CHEBI:611465
CHEMBL1680
CID383414
CID448601
CID54374
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol cyclic (2-7)-disulfide
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2-7)-disulfide
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2->7)-disulfide
D00442
DRG-0115
HMS2090C09
HS-2020
L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L- threonyl-N-(2-hydroxy-1-(hydroxymethyl)propyl)-, cyclic (2->7)-disulfide, (R-(R*
L000453
 
LS-177735
LS-187135
Longastatin
NCGC00181796-01
NCI60_025753
Ocphyl
Octreotida
Octreotida [Spanish]
Octreotide
Octreotide (USAN/INN)
Octreotide Acetate
Octreotide Acetate Salt
Octreotide [USAN:INN:BAN]
Octreotide acetate
Octreotide-LAR
Octreotidum
Octreotidum [Latin]
Octrotide
SAN 201-995
SM 201-995
SMS 201-995
SMS-201-995
Sandostatin
Sandostatine
Sandoz 201-995
UNII-RWM8CCW8GP
nchembio.184-comp3
zacycloicosane-4-carboxamide acetate
3
Rimonabantapproved, investigationalPhase 345168273-06-1, 158681-13-1104850
Synonyms:
168273-06-1
5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide
5-(p-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidinopyrazole-3-carboxamide
A 281
AC-163720
AC-731
AC1L2XM5
Acomplia
Acomplia (TN)
C14319
CHEMBL111
CID104850
D05731
DB06155
I06-0381
L000572
LS-128155
 
MolPort-003-850-185
NCGC00164572-01
Rimonabant
Rimonabant (JAN/USAN/INN)
Rimonabant [USAN:INN]
Rimoslim
Riobant
SR 141716
SR 141716A
SR-141716
SR-141716A
SR141,716A
SR141716
SR141716A
STK642500
Slimona
UNII-RML78EN3XE
ZINC01540228
[3H]SR141716A
nchembio.129-comp21
nchembio.552-comp16
4
SomatostatinPhase 314151110-01-153481605
Synonyms:
growth hormone-inhibiting hormone (GHIH)
 
somatotropin release-inhibiting factor (SRIF)
somatotropin release-inhibiting hormone
5
OxytocinapprovedPhase 2, Phase 133550-56-6439302, 53477758
Synonyms:
(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
(Arg8)-Vasopressin
(Arg8)-Vasotocin
1-({(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-(4-hydroxybenzyl)-13-[(1S)-1-methylpropyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl}carbonyl)-L-prolyl-L-leucylglycinamide
50-56-6
AC1L9735
Argipressin
Argpressin Acetate
BCBcMAP01_000094
Biotinyl-(Arg8)-Vasopressin
C00746
CHEBI:492195
CHEBI:7872
CHEMBL395429
CID439302
Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-NH2
Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2
Cys-Tyr-Ile-Thr-Asn-Cys-Gly-Leu-Gly-NH2
Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2
Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2
D00089
Disulfide bridge Cys1-Cys6
Gly-Leu-Pro-c
HS-2021
L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycinamide cyclic(1-6)-disulfide
MolPort-003-938-941
 
NCGC00167132-01
O3251_SIGMA
O4375_SIGMA
OXT
OXYTOCIN
Ocytocin
Oxitocina
Oxytocic hormone
Oxytocin
Oxytocin (JP15/USP/INN)
Oxytocin (TN)
Oxytocin 10 Usp Units In Dextrose 5%
Oxytocin 20 Usp Units In Dextrose 5%
Oxytocin 5 Usp Units In Dextrose 5%
Oxytocin Acetate
Oxytocin injection
Oxytocine
Oxytocinum
Pitocin
Pitocin (TN)
SID29217903
SID50111741
Syntocinon
Syntocinon (TN)
TI-001
alpha-Hypophamine
nchembio.184-comp2
6methionineNutraceuticalPhase 270
7
DiazoxideapprovedPhase 120364-98-73019
Synonyms:
2H-1,2, 4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide
2H-1,2,4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide
364-98-7
7-Chloro-3-methyl-1lambda~4~,2,4-benzothiadiazin-1-ol 1-oxide
7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
7-Cloro-3-metil-2H-1,2,4-benzotiodiazina-1,1-diossido
7-Cloro-3-metil-2H-1,2,4-benzotiodiazina-1,1-diossido [Italian]
7-chloro-3-methyl-4H-1
AC1L1EZN
Aroglycem
BPBio1_000016
BRD-K73109821-001-05-2
BSPBio_000014
BSPBio_001307
BSPBio_002290
Bio1_000036
Bio1_000525
Bio1_001014
Bio2_000027
Bio2_000507
C06949
C8H7ClN2O2S
CAS-364-98-7
CBiol_001750
CHEBI:4495
CHEMBL181
CID3019
CPD000058392
D 9035
D00294
D003981
D9035_SIGMA
DB01119
Diazossido
Diazossido [DCIT]
Diazossido [Italian]
Diazoxide
Diazoxide (JAN/USP/INN)
Diazoxide [USAN:INN:BAN]
Diazoxido
Diazoxido [INN-Spanish]
Diazoxidum
Diazoxidum [INN-Latin]
Dizoxide
EINECS 206-668-1
EU-0100404
Eudemine
HMS1361B09
HMS1568A16
HMS1791B09
HMS1922L22
HMS1989B09
HMS2051P20
HMS2089L04
HMS2093N12
Hyperstat
Hyperstat (TN)
Hypertonalum
I06-2041
 
IDI1_033777
KBio2_000027
KBio2_002595
KBio2_005163
KBio3_000053
KBio3_000054
KBio3_001510
KBioGR_000027
KBioGR_001776
KBioSS_000027
LS-40410
Lopac-D-9035
Lopac0_000404
MLS000028459
MLS001076071
MolPort-003-666-772
MolPort-003-941-186
Mutabase
NCGC00015380-01
NCGC00015380-02
NCGC00015380-03
NCGC00015380-05
NCGC00015380-12
NCGC00024907-01
NCGC00024907-02
NCGC00024907-03
NCGC00024907-04
NCGC00024907-05
NCGC00024907-06
NCGC00024907-07
NCGC00024907-08
NSC 64198
NSC 76130
NSC-64198
NSC64198
NSC76130
Prestwick0_000087
Prestwick1_000087
Prestwick2_000087
Prestwick3_000087
Prestwick_163
Proglicem
Proglycem
SAM001246872
SMR000058392
SPBio_001953
SPECTRUM2300206
SRG 95213
SRG-95213
Sch 6783
Sch-6783
Spectrum3_000735
Spectrum4_001248
Tocris-0964
UNII-O5CB12L4FN
VU0239714-6
ZINC03872277
diazoxide
nchembio.150-comp49
nchembio.476-comp10
8
Cholineapproved, nutraceuticalPhase 112262-49-7305
Synonyms:
(2-Hydroxyethyl)trimethyl ammonium
(2-Hydroxyethyl)trimethylammonium
(beta-hydroxyethyl)trimethylammonium
2-Hydroxy-N,N,N-trimethyl-ethanaminium
2-Hydroxy-N,N,N-trimethylethanaminium
Bilineurine
Biocolina
Biocoline
Choline
Choline cation
 
Choline ion
Cholinum
Hepacholine
Hormocline
Lipotril
N,N,N-Trimethylethanol-ammonium
N,N,N-Trimethylethanolammonium
N,N,N-trimethylethanol-ammonium
N-trimethylethanolamine
Neocolina
Paresan
trimethylethanolamine
9
Topiramateapproved23097240-79-45284627
Synonyms:
-D-fructopyranose deriv.
.beta.-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate (9CI)
2,3-4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate
2,3:4,5-Bis-O-(1-methylethylidene) .beta.-D-fructopyranose sulfamate
2,3:4,5-Bis-O-(1-methylethylidene)-36-D-fructo-pyranose sulfamate
2,3:4,5-Bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate
2,3:4,5-Di- O -isopropylidene-(beta)-D-fructopyranose sulfamate
2,3:4,5-Di-O-isopropylidene-beta-D-fructopyranose sulfamate
5H-Bis[1,3]dioxolo[4,5-b:4',5'-d]pyran, .beta.
97240-79-4
AKOS000424547
BIDD:GT0854
BIDD:PXR0127
BRN 5988957
BSPBio_002306
C052342
C07502
C12H21NO8S
CBChromo1_000352
CHEBI:129573
CHEMBL220492
CID5284627
CPD000466325
Cilag brand of topiramate
D00537
DB00273
Epitoma
Epitomax
HMS1922H06
HMS2051L09
HMS2093D20
HSDB 7531
Janssen brand of topiramate
KS-1122
KW-6485
LS-187392
LS-69764
MLS000759431
MLS001424070
McN 4853
McN-4853
MolPort-001-615-062
MolPort-002-885-869
NCGC00178714-01
Ortho brand of topiramate
 
Qudexy XR
RWJ 17021
RWJ-17021
RWJ-17021-000
S1438_Selleck
SAM001246601
SMR000466325
SPBio_000995
SPECTRUM1505801
STOCK1N-71037
Spectrum2_001128
T0575_SIGMA
TL8006021
TOR
TPM
Tipiramate
Tipiramate [French]
Tipiramato
Tipiramato [Spanish]
Topamac
Topamax
Topamax (TN)
Topamax Sprinkle
Topamax, Topiramate
Topimax
Topina
Topiramate
Topiramate (JAN/USAN/INN)
Topiramate (TPM)
Topiramate / Placebo
Topiramate [USAN:BAN:INN]
Topiramato
Topiramato [INN-Spanish]
Topiramatum
Topiramatum [INN-Latin]
Topiramic acid
Topomax
Trokendi Xr
UNII-0H73WJJ391
USL-255
[(3aS,5aR,8aR,8bS)-2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-yl]methyl sulfamate
beta-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate
beta.-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, 1-sulfamate
topiramate
topiramate tablet
topiramatum [Latin]
10
Hydrocortisoneapproved55050-23-75754, 657311
Synonyms:
(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione
1 Hydrocortisone maximum strength
11-Hydrocortisone
11-beta-Hydrocortisone
11-beta-Hydroxycortisone
11a-Hydroxycorticosterone
11alpha-Hydroxycorticosterone
11b,17,21-Trihydroxyprogesterone
11b-Hydrocortisone
11b-Hydroxycortisone
11beta,17,21-Trihydroxyprogesterone
11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione
11beta-Hydrocortisone
11beta-Hydroxycortisone
11beta-hydrocortisone
11β-hydrocortisone
17-Hydroxycorticosterone
17a-Hydroxycorticosterone
17alpha-Hydroxycorticosterone
2v95
4-Pregnen-11beta,17alpha,21-triol-3,20-dione
4-Pregnene-11alpha,21-triol 3,20-dione
4-Pregnene-11b,17a,21-triol-3,20-dione
50-23-7
8056-08-4
80562-38-5
8063-42-1
999 Itch Relieving
A-hydrocort
AC-12902
AC1L1L2B
ACETASOL HC
ACETIC ACID W/ HYDROCORTISONE
AI3-25006
AKOS001582651
Acticort
Acticort (TN)
Advanced Hydrocortisone
Aeroseb HC
Aeroseb-HC
Ala-Cort
Ala-Scalp
Alacort
Algicirtis
Alphaderm
Amberin
Anflam
Anti Itch
Anti Itch maximum strength
Anti Itch maximum strength plus
Anti-inflammatory hormone
Anti-itch
Anti-itch Scalp Relief Maximum Strength
Anucort
Anucort-HC
Anusol HC
Anusol HC (TN)
Apres Peel Soothing Balm
Aquacort
Aquanil HC
Atopalm Maximum Strength Anti-itch
Atopalm Moisturizing Hydrocortisone
Aveeno Hydrocortisone Anti Itch
B48448A1-24BA-47CA-8D9E-43E5BC949386
BPBio1_000544
BRD-K93568044-001-03-1
BSPBio_000494
Balneol-hc
Barseb HC
Basan-Corti
Beta-hc
Bio-0648
Bioelements Immediate Comfort Hydrocortisone
Budpak Anti-itch
C00735
C21H30O5
CCRIS 5854
CHEBI:17650
CHEMBL389621
CID5754
COR-OTICIN
CPD000653523
CaldeCORT Spray
Caldecort
Care One Hydrocortisone maximum strength
Cetacort
Chronocort
Cicatricure Ultra Moisturizing
Clear aid
Cleiton
Cobadex
Colocort
Colocort (TN)
Compound F
Compound F (kendall)
Cor-Tar-Quin
Corhydron
Cort-Dome
Cort-Quin
Cortaid 12-hour Advanced Anti-Itch
Cortaid Intensive Therapy Cooling
Cortaid Maximum Strength
Cortanal
Cortef
Cortef (TN)
Cortenema
Cortesal
Corticreme
Cortifair
Cortifan
Cortifoam
Cortiment
Cortisol
Cortisol alcohol
Cortisol, Hydrocortisone
Cortisolonum
Cortisone
Cortisone Cream Intensive Healing
Cortisone Maximum Strength
Cortisone maximum strength
Cortisporin
Cortisporin Otico
Cortispray
Cortizol
Cortizone 10
Cortizone 10 Cooling Cream Anti-itch
Cortizone 10 Cooling Relief
Cortizone 10 Easy Relief
Cortizone 10 Hydratensive Healing Anti Itch
Cortizone 10 Hydratensive Soothing Anti Itch
Cortizone 10 Intensive Healing
Cortizone 10 Intensive Healing Feminine Itch Relief
Cortizone 10 Intensive Healing For Eczema
Cortizone 10 Plus
Cortizone 10 Poison Ivy Relief Pads
Cortolotion
Cortonema
Cortoxide
Cortril
Cremesone
Cremicort-H
Cutisol
Cvs Anti-itch Hydrocortisone
Cvs Cools Itch Fast
Cvs Cortisone
Cvs Pharmacy Anti-itch
Cyclodextrin-encapsulated hydrocortisone
D00088
DB00741
DB07886
Delacort
Derm-Aid
Dermacort
Dermacort Anti-Itch
Dermaquest Skin Therapy Post-skin Resurfacing Balm
Dermarest Eczema Medicated
Dermaspray
Dermil
Dermocortal
Dermolate
Dg Health Hydrocortisone
Dg Health Hydrocortisone Cream Maximum Strength
Dihydrocostisone
Dioderm
Dome-cort
Domolene-HC
Dr. Sheffield Hydrocortisone Anti Itch
Drotic
Duane Reade
Duane Reade hydrocortisone
Duane Reade hydrocortisone plus 12 moisturizers
DuoCort
EINECS 200-020-1
EU-0100594
Ef corlin
Efcorbin
Efcortelan
Efcortelin
Eldecort
Eldercort
Epicort
Epicortisol
Epiderm H
Equaline Anti Itch
Equaline Anti Itch maximum strength
Equate Hydrocortisone
Esiderm H
Evacort
Family Care Hydrocortisone
Family Wellness
Family Wellness Hydrocortisone
Family Wellness Maximum Strength Hydrocortisone
Ficortril
Fiocortril
Fixmyskin Healing Balm Fragrance-free
Fixmyskin Healing Balm Unflavored
Fixmyskin Healing Balm Vanilla Flavor
Fixmyskin Healing Balm Vanilla Fragrance
Flexicort
Foille Insetti
Formu Care Anti Itch maximum strength
Fulton Street Market Anti Itch
Genacort
Genacort (lotion)
Genuine Hydrocortisone
Glycort
Good Neighbor Pharmacy Anti Itch
Good Neighbor Pharmacy Hydrocortisone
Good Neighbor Pharmacy Hydrocortisone Plus 12 Moisturizers
Good Sense Anti Itch
Gyno-Cortisone
H 4001
H-Cort
H-releve Anti-itch
H0135_SIGMA
H0396_SIGMA
H0888_SIGMA
H3160_SIGMA
H4001_SIGMA
H6909_SIGMA
HC
HC #1
HC #4
HC (HYDROCORTISONE)
HMS1569I16
HMS2090M04
HSDB 3339
HYDROCORTISONE AND ACETIC ACID
HYDROCORTISONE IN ABSORBASE
Healerz For Itches
Health Mart Pharmacy Hydrocortisone Maximum Strength Plus 12 Moisturizers
Healthy Accents Cortisone maximum strength
Heb Cort
Heb-Cort
 
Hem-easy Relief Herbal Anti-itch Maximum Itch Relief
Hi-cor
Hidalone
Hidro-Colisona
Hidrocortisona
Hidrocortisona [INN-Spanish]
Hycort
Hycortol
Hycortole
Hydracort
Hydrasson
Hydro Skin
Hydro-Adreson
Hydro-Colisona
Hydro-RX
Hydro-colisona
Hydrocort
Hydrocortal
Hydrocorticosterone
Hydrocortisone
Hydrocortisone (JP15/USP/INN)
Hydrocortisone 1 plus 10
Hydrocortisone Acetate
Hydrocortisone Anti-itch Plus
Hydrocortisone Base
Hydrocortisone Butyrate
Hydrocortisone D
Hydrocortisone HC
Hydrocortisone Intensive Healing Formula
Hydrocortisone Maximum Strength
Hydrocortisone Maximum Strength Plus 12 Moisturizers
Hydrocortisone Plus
Hydrocortisone Plus 12 Moisturizers
Hydrocortisone Probutate
Hydrocortisone Regular Strength
Hydrocortisone Sodium Phosphate
Hydrocortisone Ultra Strength
Hydrocortisone Valerate
Hydrocortisone [INN:BAN:JAN]
Hydrocortisone alcohol
Hydrocortisone anti itch
Hydrocortisone base
Hydrocortisone free alcohol
Hydrocortisone maximum strength
Hydrocortisone solution
Hydrocortisone-Water Soluble
Hydrocortisonum
Hydrocortisonum [INN-Latin]
Hydrocortistab
Hydrocortisyl
Hydrocortone
Hydroskin
Hydroxycortisone
Hysone
Hytisone
Hytone
Hytone (TN)
Hytone lotion
Idrocortisone
Idrocortisone [DCIT]
Incortin-H
Incortin-hydrogen
Intensive Healing Anti Itch
Kaiser Permanente Hydrocortisone
Kendall'S compound F
Kendall's compound F
Kera Hc Hydrocortisone
Kirkland Signature Hydrocortisone Plus maximum strength
Komed HC
Kyypakkaus
LMST02030001
LS-7439
Lacticare HC
Lacticare-HC
Lactisona
Leader Hydrocortisone
Locoid
Loesch Anti-Itch Therapy
Lopac0_000594
Lubricort
Lucky Supersoft MAXIMUM STRENGTH
MLS000069609
MLS001148103
MLS002207135
MLS002222189
Maintasone
Makesense MAXIMUM STRENGTH
Maximum Strength Cortizone 10 Quick Shot 360 Continuous
Maximum Strength Hydrocortisone
Maximum-h
Medicort
Medpride
Meijer Anti Itch
Meijer Anti Itch Cream Plus
Meijer Hydrocortisone
Meijer Hydrocortisone Plus 12 Moisturizers
Members Mark Hydrocortisone
Meusicort
Mildison
Milliderm
MolPort-001-794-637
Monistat Complete Care Instant Itch Relief
NCGC00022848-06
NCGC00022848-07
NCGC00022848-09
NCGC00022848-12
NCI60_000118
NSC 10483
NSC-10483
NSC10483
Natureplex Hydrocortisone Hydro
Neo-Cort-Dome
Neo-Cortef
Neosporin Eczema Essentials Anti Itch
Neosporin-H Ear
Nogenic HC
Nu-derm Tolereen Anti-pruritic
Nutracort
Nystaform-HC
ORLEX HC
Optef
Otalgine
Otic-Neo-Cort-Dome
Otobiotic
Otocort
Otosone-F
Pandel
Pediaderm Hc
Pediotic Suspension
Penecort
Permicort
Piyanping Antiitch
Polcort H
Premier Value Hydrocortisone
Premier Value Hydrocortisone Plus 12 Moisturizers
Preparation H Hydrocortisone
Preparation H Hydrocortisone Cream
Prepcort
Prestwick0_000447
Prestwick1_000447
Prestwick2_000447
Prestwick3_000447
Prestwick_265
Prevex HC
Proactiv Solution Anti-itch Scalp
Procto-pak
Proctocort
Proctocream HC
Proctofoam
Proctosol-hc
Proctozone HC
Procure
Protocort
Publix Hydro
Publix hydro plus
Quadrydern
Quality Choice Hydrocortisone
Quality Choice Hydrocortisone Maximum Strength
Quality Choice Maximum Strength Anti Itch
Racet
Rectasol-HC
Rectoid
Refuge Hc
Reichstein'S substance M
Reichstein's substance M
Remederm HC
Rexall Anti Itch maximum strength relief
Rexall Hydrocortisone 1
Rexall Hydrocortisone plus moisturizers
Rite Aid anti-itch
S1696_Selleck
SAM002264617
SMP1_000156
SMR000059022
SMR000653523
SPBio_002433
Safeway Hydrocortisone Plus 12 Moisturizers
Sanatison
Scalp-Cort
Scalpicin Anti-Itch Maximum Strength
Scalpicin Capilar
Scalpicin Maximum Strength
Scalpicin Scalp Itch Medication Maximum Strength
Schericur
Scheroson F
Shopko Hydrocortisone
Shopko Hydrocortisone Intensive Healing Formula
Shopko Hydrocortisone Maximum Strength
Shopko Hydrocortisone Plus 12 Moisturizers Maximum Strength
Shopko Maximum Strength
Shoprite Hydrocortisone
Sigmacort
Signef
Smart Sense Anti Itch
Smart Sense Anti Itch maximum strength
Smart Sense Hydrocortisone
Solu-cortef
Soothe Rodan Fields
Stie-cort
Stiefcorcil
Sunmark Hydrocortisone
Sunmark Hydrocortisone Plus 12 Moisturizers
Synacort
Systral Hydrocort
Tarcortin
Tecnu Corticool
Texacort
Texacort lotion 25
Thera Plus
Timocort
Topcare Hydrocortisone
Topcare Hydrocortisone Intensive Healing Formula
Topcare Hydrocortisone Plus 12 Moisturizers
Topicort
Transderma H
Traumaide
Truelipids Anti-itch Barrier
U-cort
UNII-WI4X0X7BPJ
UPCMLD-DP133
UPCMLD-DP133:001
Uniderm
Vioform-Hydrocortisone
VoSol HC
Vytone
Walgreens Hydrocortisone Plus 12 Moisturizers
Westcort
Western Family HydroCortisone
Western Family HydroCortisone Plus 12 Moisturizers
Zenoxone
[3H]cortisol
component of Lubricort
component of Neo-Cort-Dome
component of Otalgine
hydrocortisone
11
Metyraponeapproved1154-36-44174
Synonyms:
1,2-Di-3-pyridyl-2-methyl-1-propanone
2-Methyl-1,2-bis(3-pyridyl)-1-propanone
2-Methyl-1,2-di-3-pyridinyl-1-propanone
2-Methyl-1,2-di-3-pyridyl-1-propanone
2-methyl-1,2-dipyridin-3-yl-propan-1-one
2-methyl-1,2-dipyridin-3-ylpropan-1-one
37245-80-0
4885, SU
54-36-4
856525_ALDRICH
AB00513955
AC1L1HKV
AC1Q1LHX
Alliance Brand of Metyrapone
BIDD:PXR0082
BPBio1_000824
BRD-K46862739-001-03-6
BSPBio_000748
C07205
C14H14N2O
CAS-54-36-4
CHEBI:44241
CHEMBL934
CID4174
CPD-7023
CPD000059134
D00410
D008797
DB01011
EINECS 200-206-2
EU-0009322
HMS1570F10
HMS2094I07
HSDB 2500
LS-123097
METOPIRONE (TN)
MLS001066377
MLS001335881
MLS001335882
MYT
 
Mepyrapone
Metapirone
Metapyron
Methapyrapone
Methbipyranone
Methopirapone
Methopyrapone
Methopyrinine
Methopyrone
Metirapona
Metirapona [INN-Spanish]
Metopiron
Metopirone
Metopyrone
Metroprione
Metyrapon
Metyrapone
Metyrapone (JP15/USP/INN)
Metyrapone Alliance Brand
Metyrapone Novartis Brand
Metyrapone [USAN:INN:BAN:JAN]
Metyraponum
Metyraponum [INN-Latin]
MolPort-001-794-644
NCGC00016242-01
NCGC00161837-01
NSC 25265
NSC25265
Novartis Brand of Metyrapone
Prestwick0_000904
Prestwick1_000904
Prestwick2_000904
Prestwick3_000904
SAM002297829
SMR000059134
SPBio_002947
ST51006925
Su 4885
Su-4885
UNII-ZS9KD92H6V
ZINC00001728
metyrapone
12
Exenatideapproved, investigational257141758-74-915991534
Synonyms:
141732-76-5
141758-74-9
286014-72-0
335149-21-8
AC 2993
AC 2993 LAR
AC 2993A
AC-2993
AC002993
AC2993
AC2993a
Bydureon
Byetta
 
C074031
CHEBI:490990
CHEMBL414357
Ex4 peptide
Exenatide
Exenatide Synthetic
Exenatide synthetic
Exendin 4
Exendin 4 (Heloderma suspectum)
Exendin-4
Extendin-4
LY2148568
Synthetic exendin-4
UNII-9P1872D4OL
13
Cosyntropinapproved2416960-16-016129617
Synonyms:
16960-16-0
ATCH (1-24)
Adrenocorticotropic hormone 1-24
COSYNTROPIN
Corticotropin-(1-24)
Corticotropin-(1-24) tetracosapeptide
Cortrosyn
Cortrosyn (TN)
 
Cosyntropin
Cosyntropin (USAN)
D00284
SYSMEHFRWGKPVGKKRRPVKVYP
SerTyrSerMetGluHisPheArgTrpGlyLysProValGlyLysLysArgArgProValLysValTyrPro
Tetracosactide
Tetracosactide (INN)
alpha(1-24)-Corticotrophin
beta(1-24)-Corticotrophin
14
Epinephrineapproved76851-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenaclick
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
Auvi-q
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine bitartrate
Epinephrine chloride
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr
Epipen Jr.
Epipen Jr. Auto-Injector
Epipen jr
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
 
Esphygmogenina
Exadrin
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
Primatene Mist Refill
Prime Asthma Relief
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
15
Anastrozoleapproved, investigational252120511-73-12187
Synonyms:
.alpha.,alpha.,.alpha.',.alpha.'-tetramethyl-5(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
1,3-benzenediacetonitrile, a, a, a', a'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)
120511-73-1
2,2'-(5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene)bis(2-methylpropionitrile)
2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]bis(2-methylpropanenitrile)
2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)benzene-1,3-diyl]bis(2-methylpropanenitrile)
2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile
AC-4234
AC1L1D49
Anastrazole
Anastrole
Anastrozol
Anastrozole
Anastrozole (JAN/USAN/INN)
Anastrozole [USAN:INN:BAN]
Arimidex
Arimidex (TN)
Arimidex (Zeneca)
Arimidex, Anastrozole
Asiolex
Astra brand of anastrozole
AstraZeneca brand of anastrozole
C08159
C090450
C17H19N5
CHEBI:2704
CHEMBL1399
CID2187
CPD000466301
 
D00960
DB01217
HMS2052M11
HMS2089N10
HSDB 7462
I06-0021
ICI D1033
ICI-D 1033
ICI-D1033
LS-29563
MLS000759396
MLS001424217
MolPort-005-933-078
NCGC00164619-01
NSC719344
S1188_Selleck
SAM001246525
SBB066057
SMR000466301
UNII-2Z07MYW1AZ
ZD 1033
ZD-1033
ZD1033
ZINC00000941
Zeneca ZD 1033
Zeneca brand of anastrozole
alpha,alpha,Alpha',alpha'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
alpha,alpha,alpha',alpha'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
anastrazole
anastrozole
16Insulin, Globin Zinc4069
17Hydrocortisone 17-butyrate 21-propionate550
18Hydrocortisone acetate550
19Cortisol succinate550
20Hydrocortisone-17-butyrate550
21insulin4069
22Glucagon-Like Peptide 1652
23Mydriatics470
24Racepinephrine768
25Epinephryl borate768
26PokeNutraceutical3

Interventional clinical trials:

(show top 50)    (show all 54)
idNameStatusNCT IDPhase
1Is There a Sensibility Increased in the Growth Hormone at Child With Prader-Willi Syndrome?CompletedNCT01298180Phase 4
2Liraglutide Use in Prader-Willi SyndromeTerminatedNCT01542242Phase 4
3Study to Assess the Efficacy and Safety of Eutropin in Prader-Willi SyndromeRecruitingNCT02204163Phase 3
4Effect of Rimonabant on Weight Gain and Body Composition in Adults With Prader Willi SyndromeRecruitingNCT00603109Phase 3
5Growth Hormone Use in Adults With Prader-Willi SyndromeRecruitingNCT00444964Phase 3
6Effect of Liraglutide for Weight Management in Paediatric Subjects With Prader-Willi SyndromeRecruitingNCT02527200Phase 3
7Double-Blind, Placebo Controlled, Phase 3 Trial of ZGN-440 (Beloranib) in Obese Subjects With Prader-Willi SyndromeActive, not recruitingNCT02179151Phase 3
8Prader-Willi Syndrome and AppetiteTerminatedNCT00175305Phase 3
9Behavioral Treatment of Obsessive-Compulsive Symptoms in Youth With Prader-Willi Syndrome: A Pilot ProjectCompletedNCT00742664Phase 1, Phase 2
10Treatment of Hyperphagia Behavioral Symptoms in Children and Adults Diagnosed With Prader-Willi SyndromeCompletedNCT01968187Phase 2
11An Efficacy, Safety, and Pharmacokinetics Study of Beloranib in Obese Subjects With Prader-Willi SyndromeCompletedNCT01818921Phase 2
12Comparative Study Between Prader-Willi Patients Who Take Oxytocin Versus PlaceboCompletedNCT01038570Phase 2
13Evaluation of Tolerance, Suckling and Food Intake After Repeated Nasals Administrations of Oxytocin in PWS InfantsCompletedNCT02205034Phase 1, Phase 2
14Tolerance of Intranasal Administration of OT in Prader-Willi Newborn BabiesCompletedNCT01548521Phase 1, Phase 2
15Ph 2 Trial to Evaluate Safety & Efficacy of RM-493 in Obese Patients With Prader-Willi SyndromeRecruitingNCT02311673Phase 2
16Oxytocin vs. Placebo for the Treatment Hyperphagia in Children and Adolescents With Prader-Willi SyndromeRecruitingNCT02629991Phase 2
17Oxytocin Trial in Prader-Willi SyndromeCompletedNCT02013258Phase 1
18Bioequivalence of Two Somatropin Products (Norditropin® Versus Genotropin®) in Healthy Adult VolunteersCompletedNCT01401244Phase 1
19Deep Brain Stimulation for the Treatment of Obesity in Patients With Prader-Willi SyndromeRecruitingNCT02297022Phase 1
20Parents Resources for Decreasing the Incidence of Change Triggered Temper OutburstsRecruitingNCT02567357Phase 1
21Clinical Study of Diazoxide Choline Controlled-Release Tablet (DCCR) in Patients With Prader-Willi SyndromeActive, not recruitingNCT02034071Phase 1
22Hypoglycemia in Prader-Willi SyndromeCompletedNCT01897363
23Characteristics of Prader-Willi Syndrome and Early-onset Morbid ObesityCompletedNCT00375089
24Treatment of Self-Injurious Behavior in Individuals With Prader-Willi SyndromeCompletedNCT00065923
25Plasma Adiponectin Level and Sleep Structures in Children With Prader-Willi SyndromeCompletedNCT01622751
26Plasma Adiponectin Level and Vascular Endothelial and Smooth Muscle Cell Function in Children With Prader-Willi SyndromeCompletedNCT01479322
27Increased Expression of Adiponectin Receptor 2 in the Mononuclear Cells in Children With Prader-Willi SyndromeCompletedNCT00800852
28Retrospective Observational Study on Efficacy and Safety of Norditropin® in Children With Prader-Willi SyndromeCompletedNCT00705172
29Nordic Study on the Effects of Growth Hormone (Norditropin SimpleXx) Treatment in Adults With Prader-Willi SyndromeCompletedNCT00372125
30The Intestinal Function in People With Prader-Willi SyndromeCompletedNCT01523288
31Cortisol Activity in Patients With Prader-Willi Syndrome and Healthy ControlsCompletedNCT00932932
32Sleep Abnormalities in Rare Genetic Disorders: AS, RTT, and PWCompletedNCT02670694
33Correlation of Hyperghrelinemia With Carotid Artery Intima-Media Thickness in Children With Prader-Willi SyndromeCompletedNCT00474643
34Ghrelin Suppression by Octreotide in Prader-WilliCompletedNCT01613495
35Characterization of Transcriptional Regulators of Ghrelin Hormone Which Causes Genetic ObesityCompletedNCT01404624
36Macronutrient Regulation of Ghrelin and Peptide YYCompletedNCT02464514
37Study of Phenotype and Genotype Correlations in Patients With Contiguous Gene Deletion SyndromesCompletedNCT00004351
38Brain-Derived Neurotrophic Factor in Obesity and Brain FunctionCompletedNCT01517048
39Family-based Intervention for Youth With Prader-Willi Syndrome: The Active Play at Home StudyRecruitingNCT02058342
40Pilot Study of Startle-response Test to Assess Transcranial Direct Current Stimulation-induced Modulation of Hyperphagia in Prader-Willi SyndromeRecruitingNCT01863017
41Diagnosis of Central Adrenal Insufficiency in Patients With Prader-Willi SyndromeRecruitingNCT02368379
42Gut Derived Hormones, Body Composition and Metabolism in Prader-Willi SyndromeRecruitingNCT00551343
43PWS European Blood Bank for Infants and Controls From 0 to 48 MonthsRecruitingNCT02529085
44SNP-based Microdeletion and Aneuploidy RegisTry (SMART)RecruitingNCT02381457
45Development of Non-invasive Prenatal Test for Microdeletion and Other Genetic Syndromes Based on Cell Free DNARecruitingNCT02109770
46Development of Non-invasive Prenatal Screening Test for Microdeletions Based on Fetal DNA Isolated From Maternal BloodRecruitingNCT01852708
47Prader-Willi Syndrome Macronutrient StudyActive, not recruitingNCT02011360
48Effects of Exenatide on Overweight Adolescents With Prader-Willi SyndromeActive, not recruitingNCT01444898
49Aromatase Inhibitor in Bone Maturation, Children With Silver Russell or Prader-Willi SyndromeActive, not recruitingNCT01520467
50Experience With Growth Hormone (GH) in Children Under 2 Years With Prader-Willi Syndrome (PWS) in the Pediatric Endocrine Department of the Hospital of SabadellNot yet recruitingNCT02205450

Search NIH Clinical Center for Prader-Willi Syndrome


Cochrane evidence based reviews: Prader-Willi Syndrome

Genetic Tests for Prader-Willi Syndrome

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Genetic tests related to Prader-Willi Syndrome:

id Genetic test Affiliating Genes
1 Prader-Willi Syndrome22 24

Anatomical Context for Prader-Willi Syndrome

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MalaCards organs/tissues related to Prader-Willi Syndrome:

33
Brain, Testes, Skin, Bone, Pituitary, Thyroid, Heart

Animal Models for Prader-Willi Syndrome or affiliated genes

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MGI Mouse Phenotypes related to Prader-Willi Syndrome:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053759.2GH1, GHRL, IGF1, LEP, OCA2, PYY
2MP:00053799.0GH1, GHRL, IGF1, LEP, MAGEL2, OCA2
3MP:00053898.6GABRB3, GH1, IGF1, LEP, MAGEL2, OCA2
4MP:00053868.4GABRA5, GABRB3, GHRL, LEP, MAGEL2, NDN

Publications for Prader-Willi Syndrome

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Articles related to Prader-Willi Syndrome:

(show top 50)    (show all 729)
idTitleAuthorsYear
1
Autism spectrum disorder in Prader-Willi syndrome: A systematic review. (26331980)
2015
2
Dietary Energy Intake, Body Composition and Resting Energy Expenditure in Prepubertal Children with Prader-Willi Syndrome before and during Growth Hormone Treatment: A Randomized Controlled Trial. (25764996)
2015
3
Differential regulation of non-protein coding RNAs from Prader-Willi Syndrome locus. (25246219)
2014
4
Patterns of habitual physical activity in youth with and without Prader-Willi Syndrome. (25129202)
2014
5
Social and emotional processing in Prader-Willi syndrome: genetic subtype differences. (23536992)
2013
6
Divergent structural brain abnormalities between different genetic subtypes of children with Prader-Willi syndrome. (24144356)
2013
7
Impaired theory of mind and symptoms of Autism Spectrum Disorder in children with Prader-Willi syndrome. (23792373)
2013
8
The Mini-Gastric Bypass in the Management of Morbid Obesity in Prader-Willi Syndrome: A Viable Option? (24063639)
2013
9
Prader-Willi syndrome and sleep-disordered breathing. (24126982)
2013
10
Update on body composition and bone density in children with Prader-Willi syndrome. (23615452)
2013
11
Prader-Willi syndrome - care of adults in general practice. (23529462)
2013
12
Good cognitive performances in a child with Prader-Willi syndrome. (24238393)
2013
13
Comparison of body composition, basal metabolic rate and metabolic outcomes of adults with Prader Willi syndrome or lesional hypothalamic disease, with primary obesity. (23318724)
2013
14
Intraoperative adrenal insufficiency in a patient with prader-willi syndrome. (23024738)
2012
15
Unique and atypical deletions in Prader-Willi syndrome reveal distinct phenotypes. (22045295)
2012
16
Experience of severe desaturation during anesthetic induction period in an obese adult patient with Prader-Willi syndrome -A case report-. (22379576)
2012
17
Prader--Willi syndrome: 16-year experience in Hong Kong. (22685788)
2012
18
Prader-Willi Syndrome: Obesity due to Genomic Imprinting. (22043168)
2011
19
Clinical reporta89health supervision for children with Prader-Willi syndrome. (21187304)
2011
20
Assessment of body composition using bioelectrical impedance analysis in Prader-Willi syndrome. (22118318)
2011
21
Trajectory and outcomes of speech language therapy in the Prader-Willi syndrome (PWS): case report. (21552737)
2011
22
Treatment of scoliosis in patients affected with Prader-Willi syndrome using various techniques. (20550681)
2010
23
Normal cortisol response on low-dose synacthen (1 microg) test in children with Prader Willi syndrome. (20810574)
2010
24
Plasma adiponectin level and sleep structures in children with Prader-Willi syndrome. (19912511)
2010
25
Morbid obesity in an adolescent with Prader-Willi syndrome. (19543650)
2009
26
Is scoliosis an issue for giving growth hormone to children with Prader-Willi syndrome? (19028967)
2008
27
Randomized controlled GH trial: effects on anthropometry, body composition and body proportions in a large group of children with Prader-Willi syndrome. (18363884)
2008
28
Interdisciplinary behavioral intervention for life-threatening obesity in an adolescent with Prader-Willi syndrome - a case report. (18408535)
2008
29
Food-related neural circuitry in Prader-Willi syndrome: response to high- versus low-calorie foods. (18311513)
2008
30
The phenomenology and diagnosis of psychiatric illness in people with Prader-Willi syndrome. (18177526)
2008
31
Pituitary abnormalities in Prader-Willi syndrome and early onset morbid obesity. (17431897)
2008
32
Behavior in Prader-Willi syndrome: relationship to genetic subtypes and age. (18665884)
2008
33
Adrenarche in Prader-Willi syndrome appears not related to insulin sensitivity and serum adiponectin. (17085944)
2007
34
Prader-Willi syndrome: medical prevention and behavioral challenges. (17562587)
2007
35
Nutrient intake and body composition variables in Prader-Willi syndrome--effect of growth hormone supplementation and genetic subtype. (17550213)
2007
36
Changing rates of genetic subtypes of Prader-Willi syndrome in the UK. (16957680)
2007
37
Near demise of a child with Prader-Willi syndrome during elective orchidopexy. (16879524)
2006
38
Absence of microdeletions in the Y chromosome in patients with Prader-Willi syndrome with cryptorchidism. (11869370)
2002
39
Evidence for the role of PWCR1/HBII-85 C/D box small nucleolar RNAs in Prader-Willi syndrome. (12154412)
2002
40
Assessment of SNRPN expression as a molecular tool in the diagnosis of Prader-Willi syndrome. (10229769)
1999
41
Serum leptin concentrations in obese women with Down syndrome and Prader-Willi syndrome. (10368796)
1999
42
Growth failure in Prader-Willi syndrome is secondary to growth hormone deficiency. (9568805)
1998
43
The mouse Necdin gene is expressed from the paternal allele only and lies in the 7C region of the mouse chromosome 7, a region of conserved synteny to the human Prader-Willi syndrome region. (9412790)
1997
44
The genetic basis for Prader-Willi syndrome: the importance of imprinted genes. (9401540)
1997
45
Exclusion of SNRPN as a major determinant of Prader-Willi syndrome by a translocation breakpoint. (8630505)
1996
46
Validation studies of SNRPN methylation as a diagnostic test for Prader-Willi syndrome. (8957518)
1996
47
Kleine-Levin syndrome in a boy with Prader-Willi syndrome. (8650457)
1996
48
Difference in methylation patterns within the D15S9 region of chromosome 15q11-13 in first cousins with Angelman syndrome and Prader-Willi syndrome. (8266996)
1993
49
Trimethylaminuria in a girl with Prader-Willi syndrome and del(15)(q11q13). (8434620)
1993
50
Coexistence of Prader-Willi syndrome, congenital ectropion uveae with glaucoma, and factor XI deficiency. (3086578)
1986

Variations for Prader-Willi Syndrome

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Expression for genes affiliated with Prader-Willi Syndrome

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Search GEO for disease gene expression data for Prader-Willi Syndrome.

Pathways for genes affiliated with Prader-Willi Syndrome

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Pathways related to Prader-Willi Syndrome according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.0GABRA5, GABRB3
29.6GH1, IGF1, LEP, NDN
3
Show member pathways
9.6GH1, GHRL, IGF1, LEP

GO Terms for genes affiliated with Prader-Willi Syndrome

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Cellular components related to Prader-Willi Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1GABA-A receptor complexGO:190271110.0GABRA5, GABRB3

Biological processes related to Prader-Willi Syndrome according to GeneCards Suite gene sharing:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of insulin-like growth factor receptor signaling pathwayGO:004356810.4GH1, IGF1
2innervationGO:006038410.4GABRA5, GABRB3
3positive regulation of tyrosine phosphorylation of Stat5 proteinGO:004252310.3GH1, IGF1
4adult feeding behaviorGO:000834310.3GHRL, LEP
5cochlea developmentGO:009010210.2GABRA5, GABRB3
6bone mineralization involved in bone maturationGO:003563010.2IGF1, LEP
7inner ear receptor cell developmentGO:006011910.2GABRA5, GABRB3
8neuron developmentGO:00486669.9GABRA5, GABRB3, NDN
9positive regulation of JAK-STAT cascadeGO:00464279.7GH1, LEP

Molecular functions related to Prader-Willi Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1GABA-A receptor activityGO:000489010.4GABRA5, GABRB3
2hormone activityGO:00051799.4GH1, GHRL, IGF1, LEP, PYY

Sources for Prader-Willi Syndrome

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet