MCID: PRD004
MIFTS: 23

Prediabetes Syndrome malady

Summaries for Prediabetes Syndrome

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33MedlinePlus, 32MalaCards
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MedlinePlus:33 Prediabetes means you have blood glucose, or blood sugar, levels that are higher than normal but not high enough to be called diabetes. glucose comes from the foods you eat. too much glucose in your blood can damage your body over time. if you have prediabetes, you are more likely to develop type 2 diabetes, heart disease, and stroke. most people with prediabetes don't have any symptoms. your doctor can test your blood to find out if your blood glucose levels are higher than normal. if you are 45 years old or older, your doctor may recommend that you be tested for prediabetes, especially if you are overweight. losing weight - at least 5 to 10 percent of your starting weight - can prevent or delay diabetes or even reverse prediabetes. that's 10 to 20 pounds for someone who weighs 200 pounds. you can lose weight by cutting down on the amount of calories and fat you eat and being physically active at least 30 minutes a day. being physically active makes your body's insulin work better. your doctor may also prescribe medicine to help control the amount of glucose in your blood. nih: national institute of diabetes and digestive and kidney diseases

MalaCards: Prediabetes Syndrome, also known as prediabetic state, is related to obesity and diabetes mellitus. An important gene associated with Prediabetes Syndrome is SERPINE1 (serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1). Affiliated tissues include testes, kidney and heart.

Aliases & Classifications for Prediabetes Syndrome

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 33MedlinePlus, 60UMLS, 56SNOMED-CT, 34MeSH
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Aliases & Descriptions:

prediabetes syndrome 8 10 60
prediabetic state 8 44
prediabetes 8 33


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Disease Ontology8 DOID:11716
SNOMED-CT56 15777000, 9414007
MeSH34 D011236

Related Diseases for Prediabetes Syndrome

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Prediabetes Syndrome:



Diseases related to prediabetes syndrome

Clinical Features for Prediabetes Syndrome

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Drugs & Therapeutics for Prediabetes Syndrome

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Prediabetes Syndrome

Drug clinical trials:

Search ClinicalTrials for Prediabetes Syndrome

Search NIH Clinical Center for Prediabetes Syndrome

Search CenterWatch for Prediabetes Syndrome

Genetic Tests for Prediabetes Syndrome

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Anatomical Context for Prediabetes Syndrome

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32MalaCards
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MalaCards organs/tissues related to Prediabetes Syndrome:

32
Testes, Kidney, Heart

Animal Models for Prediabetes Syndrome or affiliated genes

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Publications for Prediabetes Syndrome

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50PubMed
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Articles related to Prediabetes Syndrome:

idTitleAuthorsYear
1
Correction: Prediabetes Is Associated with an Increased Risk of Testosterone Deficiency, Independent of Obesity and Metabolic Syndrome. (24348968)
2013
2
Soluble CD40 ligand, soluble P-selectin and von Willebrand factor levels in subjects with prediabetes: the impact of metabolic syndrome. (22100896)
2012
3
Effect of rosiglitazone on plasma adiponectin levels and arterial stiffness in subjects with prediabetes or non-diabetic metabolic syndrome. (16498057)
2006
4
Role of hypoadiponectinemia in the metabolic syndrome and its association with post-glucose challenge hyper-free fatty acidemia: a study in prediabetic Japanese males. (16785613)
2006
5
Soluble P-selectin and CD40L levels in subjects with prediabetes, diabetes mellitus, and metabolic syndrome--the Chennai Urban Rural Epidemiology Study. (16423632)
2006
6
Prediabetes in obese youth: a syndrome of impaired glucose tolerance, severe insulin resistance, and altered myocellular and abdominal fat partitioning. (14511928)
2003
7
Cardiovascular risk factors and the prediabetic syndrome. (8862692)
1996

Genetic Variations for Prediabetes Syndrome

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Expression for genes affiliated with Prediabetes Syndrome

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Prediabetes Syndrome

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Pathways for genes affiliated with Prediabetes Syndrome

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Compounds for genes affiliated with Prediabetes Syndrome

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GO Terms for genes affiliated with Prediabetes Syndrome

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16Gene Ontology
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Biological processes related to Prediabetes Syndrome according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1transcription, DNA-dependentGO:0063519.1SERPINE1, HSF5

Products for genes affiliated with Prediabetes Syndrome

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Prediabetes Syndrome

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet