MCID: PRD004
MIFTS: 43

Prediabetes Syndrome malady

Categories: Metabolic diseases

Aliases & Classifications for Prediabetes Syndrome

Aliases & Descriptions for Prediabetes Syndrome:

Name: Prediabetes Syndrome 12 14 69
Prediabetic State 12 52 42
Prediabetes 12 41 14

Classifications:



External Ids:

Disease Ontology 12 DOID:11716
ICD10 33 R73.09
MeSH 42 D011236
NCIt 47 C122685
UMLS 69 C0362046

Summaries for Prediabetes Syndrome

MedlinePlus : 41 prediabetes means you have blood glucose, or blood sugar, levels that are higher than normal but not high enough to be called diabetes. glucose comes from the foods you eat. too much glucose in your blood can damage your body over time. if you have prediabetes, you are more likely to develop type 2 diabetes, heart disease, and stroke. most people with prediabetes don't have any symptoms. your doctor can use an a1c test or another blood test to find out if your blood glucose levels are higher than normal. if you are 45 years old or older, your doctor may recommend that you be tested for prediabetes, especially if you are overweight. losing weight - at least 5 to 10 percent of your starting weight - can prevent or delay diabetes or even reverse prediabetes. that's 10 to 20 pounds for someone who weighs 200 pounds. you can lose weight by cutting down on the amount of calories and fat you eat and being physically active at least 30 minutes a day. being physically active makes your body's insulin work better. your doctor may also prescribe medicine to help control the amount of glucose in your blood. nih: national institute of diabetes and digestive and kidney diseases

MalaCards based summary : Prediabetes Syndrome, also known as prediabetic state, is related to myocardial infarction and fatty liver disease. An important gene associated with Prediabetes Syndrome is INS (Insulin), and among its related pathways/superpathways are Common Cytokine Receptor Gamma-Chain Family Signaling Pathways and Glucose / Energy Metabolism. The drugs Metformin and Saxagliptin have been mentioned in the context of this disorder. Affiliated tissues include testes, heart and kidney, and related phenotypes are homeostasis/metabolism and growth/size/body region

Wikipedia : 71 Prediabetes is the precursor stage before diabetes mellitus in which not all of the symptoms required to... more...

Related Diseases for Prediabetes Syndrome

Diseases related to Prediabetes Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 138)
id Related Disease Score Top Affiliating Genes
1 myocardial infarction 28.5 ADIPOQ ALB APOB COG2 CRP IL6
2 fatty liver disease 11.1
3 diabetes mellitus, noninsulin-dependent 10.9
4 diabetes mellitus, insulin-dependent 10.9
5 nonalcoholic steatohepatitis 10.8
6 acquired angioedema 10.3 ADIPOQ PPARG
7 acute infection of pinna 10.3 CRP INS
8 acrocephalopolydactyly 10.3 ADIPOQ LEP
9 iida kannari syndrome 10.2 ADIPOQ INS PPARG
10 triphalangeal thumbs and dislocation of patella 10.2 GAD1 INS
11 autosomal recessive congenital ichthyosis 10.2 INS LEP PPARG
12 leg dermatosis 10.2 ADIPOQ INS LEP
13 not otherwise specified 3-mga-uria type 10.2 ADIPOQ INS LEP
14 hyperphosphatemia 10.2 INS LEP PPARG
15 coloboma of iris 10.2 CRP IL6
16 cataract 10.2 ALB CRP INS
17 malignant perineurioma 10.2 ADIPOQ LEP
18 autoimmune disease 1 10.2 CRP INS TCF7L2
19 exophthalmic ophthalmoplegia 10.2 ADIPOQ ALB LEP
20 mucinoses 10.2 ADIPOQ IL6 LEP
21 cholesteatoma 10.1 ADIPOQ ALB LEP
22 cutaneous sclerosis 10.1 CRP IL6
23 neurogenic arthropathy 10.1 ADIPOQ DPP4 INS LEP
24 submucous uterine fibroid 10.1 ALB INS
25 hypersensitivity syndrome, carbamazepine-induced 10.1 ALB INS
26 shoulder impingement syndrome 10.1 ALB CRP IL6
27 thymus clear cell carcinoma 10.1 ADIPOQ INS LEP PPARG
28 fallopian tube serous adenocarcinoma 10.1 ALB CRP IL6
29 breast hemangiopericytoma 10.1 CRP IL6 LEP
30 bile duct mucoepidermoid carcinoma 10.1 ALB CRP LEP
31 plummer's disease 10.1 ALB CRP IL6
32 allergic bronchopulmonary aspergillosis 10.1 ALB CRP IL6
33 ischemic optic neuropathy 10.1 ALB CRP IL6
34 bladder sarcoma 10.1 ALB IL6 LEP
35 chordoid meningioma 10.1 ALB CRP IL6
36 choroiditis 10.1 ALB CRP IL6
37 chronic tic disorder 10.1 ADIPOQ ALB LEP
38 rift valley fever 10.1 ALB CRP IL6
39 amelogenesis imperfecta 10.1 ALB CRP IL6
40 colon adenocarcinoma 10.1 ALB CRP IL6
41 antidepressant type abuse 10.1 ADIPOQ INS LEP TCF7L2
42 asbestosis 10.1 ALB CRP IL6
43 bacterial meningitis 10.1 ALB CRP IL6
44 sclerosing adenosis of breast 10.1 ALB CRP IL6
45 bare lymphocyte syndrome, type i 10.1 ADIPOQ CRP IL6 PPARG
46 meningitis 10.1 ADIPOQ IL6 INS LEP
47 foodborne botulism 10.1 ALB CRP IL6
48 uterine ligament clear cell adenocarcinoma 10.1 ALB CRP IL6
49 hyperuricemia, pulmonary hypertension, renal failure, and alkalosis 10.1 ALB CRP IL6
50 pulmonary eosinophilia 10.1 ALB CRP IL6

Graphical network of the top 20 diseases related to Prediabetes Syndrome:



Diseases related to Prediabetes Syndrome

Symptoms & Phenotypes for Prediabetes Syndrome

MGI Mouse Phenotypes related to Prediabetes Syndrome:

44 (show all 11)
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.24 COG2 CRP DPP4 GAD1 IL6 INS
2 growth/size/body region MP:0005378 10.22 IL6 INS LEP PPARG PRKAA2 SLC30A8
3 endocrine/exocrine gland MP:0005379 10.17 ADIPOQ ALB DPP4 GAD1 IL6 INS
4 cellular MP:0005384 10.16 ADIPOQ ALB APOB GAD1 IL6 INS
5 behavior/neurological MP:0005386 10.13 AMPD2 GAD1 IL6 INS LEP PPARG
6 adipose tissue MP:0005375 10.04 ADIPOQ IL6 INS LEP PPARG PRKAA2
7 liver/biliary system MP:0005370 9.97 ADIPOQ ALB APOB IL6 INS LEP
8 muscle MP:0005369 9.91 ADIPOQ ALB APOB IL6 INS LEP
9 neoplasm MP:0002006 9.63 ADIPOQ ALB IL6 LEP PPARG TCF7L2
10 nervous system MP:0003631 9.61 AMPD2 APOB GAD1 IL6 INS LEP
11 renal/urinary system MP:0005367 9.23 IL6 INS LEP PPARG PRKAA2 ADIPOQ

Drugs & Therapeutics for Prediabetes Syndrome

Drugs for Prediabetes Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 444)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Metformin Approved Phase 4,Phase 3,Phase 2,Phase 1 657-24-9 14219 4091
2
Saxagliptin Approved Phase 4,Phase 3 361442-04-8 11243969
3
Insulin Glargine Approved Phase 4,Phase 3,Phase 1 160337-95-1
4
Zinc Approved Phase 4,Phase 2,Phase 3,Phase 1 7440-66-6 32051 23994
5
Rosiglitazone Approved, Investigational Phase 4,Phase 3,Phase 2 122320-73-4 77999
6
Ethanol Approved Phase 4,Phase 3 64-17-5 702
7
Benzocaine Approved Phase 4,Phase 3,Phase 2 1994-09-7, 94-09-7 2337
8
Acarbose Approved, Investigational Phase 4,Phase 3 56180-94-0 441184
9
Methyltestosterone Approved Phase 4,Phase 3 58-18-4 6010
10
Testosterone Approved, Investigational Phase 4,Phase 3 58-22-0 6013
11
Exenatide Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 141758-74-9 15991534
12
Hydroxychloroquine Approved Phase 4 118-42-3 3652
13
Aripiprazole Approved, Investigational Phase 4 129722-12-9 60795
14
Olanzapine Approved, Investigational Phase 4,Phase 3 132539-06-1 4585
15
Pioglitazone Approved, Investigational Phase 4,Phase 2,Phase 1 111025-46-8 4829
16
Hydrochlorothiazide Approved, Vet_approved Phase 4,Phase 2,Early Phase 1 58-93-5 3639
17
Losartan Approved Phase 4,Phase 2 114798-26-4 3961
18
Trandolapril Approved Phase 4 87679-37-6 5484727
19
Verapamil Approved Phase 4 52-53-9 2520
20
Abacavir Approved, Investigational Phase 4 136470-78-5 65140 441300
21
Lamivudine Approved, Investigational Phase 4,Phase 3 134678-17-4 60825
22
Lopinavir Approved Phase 4 192725-17-0 92727
23
Ritonavir Approved, Investigational Phase 4 155213-67-5 392622
24
Zidovudine Approved Phase 4,Phase 3 30516-87-1 35370
25
Liraglutide Approved Phase 4,Phase 3,Phase 2 204656-20-2
26
Dopamine Approved Phase 4,Phase 3 51-61-6, 62-31-7 681
27
Ziprasidone Approved Phase 4,Phase 3 146939-27-7 60854
28
Linagliptin Approved Phase 4 668270-12-0 10096344
29
Fluspirilene Approved Phase 4 1841-19-6 3396
30
Pravastatin Approved Phase 4 81093-37-0 54687
31
Heparin Approved, Investigational Phase 4 9005-49-6 772 46507594
32
Ticagrelor Approved Phase 4 274693-27-5 9871419
33
Ticlopidine Approved Phase 4 55142-85-3 5472
34
Leuprolide Approved, Investigational Phase 4,Phase 2 53714-56-0 3911 657181
35
Progesterone Approved, Vet_approved Phase 4 57-83-0 5994
36
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 2,Phase 3 59-30-3 6037
37 tannic acid Approved, Nutraceutical Phase 4,Phase 3,Phase 2
38
Cholecalciferol Approved, Nutraceutical Phase 4,Phase 2,Phase 3,Phase 1 67-97-0 6221 10883523 5280795
39
Ergocalciferol Approved, Nutraceutical Phase 4,Phase 2,Phase 3,Phase 1 50-14-6 5280793
40
Menadione Approved, Nutraceutical Phase 4,Phase 1,Phase 2 58-27-5 4055
41
Phytonadione Approved, Nutraceutical Phase 4,Phase 1,Phase 2 84-80-0 4812 5284607
42
Niacin Approved, Investigational, Nutraceutical Phase 4 59-67-6 938
43
Nicotinamide Approved, Nutraceutical Phase 4 98-92-0 936
44
Pyridoxal Approved, Nutraceutical Phase 4 66-72-8 1050
45
Pyridoxine Approved, Nutraceutical, Vet_approved Phase 4 65-23-6 1054
46
Clopidogrel Approved, Nutraceutical Phase 4 120202-66-6, 113665-84-2 60606
47 Dipeptidyl-Peptidase IV Inhibitors Phase 4,Phase 3,Phase 2
48 HIV Protease Inhibitors Phase 4,Phase 3,Phase 2,Early Phase 1
49 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
50 Hormones Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 717)
id Name Status NCT ID Phase
1 Effect of Saxagliptin on Pre-Diabetes Mellitus and Obesity Unknown status NCT01960205 Phase 4
2 Curcumin Therapy in Patients With Impaired Glucose Tolerance and Insulin Resistance Unknown status NCT01052025 Phase 4
3 Intensity of Exercise and Glucose Metabolism Unknown status NCT01649219 Phase 4
4 Can Insulin Glargine Improve Myocardial Function in Patients With T2D and Coronary Artery Disease (CAD) Unknown status NCT01035528 Phase 4
5 Clinical Study to Evaluate the Efficacy of Anakinra in Patients With Rheumatoid Arthritis and Diabetes Unknown status NCT02236481 Phase 4
6 Comparing a Nucleoside-Analogue-Sparing Regimen and a Protease-Inhibitor-Sparing Regimen in HIV Infected Patients Unknown status NCT00135460 Phase 4
7 Effect of Atorvastatin on Glycemic Control in Prediabetic Patients Completed NCT02470455 Phase 4
8 Effect of Dapagliflozin on Insulin Secretion and Insulin Sensitivity in Patients With Prediabetes Completed NCT02700334 Phase 4
9 Effects of Antidiabetic Medications on the Postprandial State in Prediabetes Completed NCT02104739 Phase 4
10 Effect of Rubus Occidentalis Extract on Plasma Glucose Levels in Subject With Prediabetes Completed NCT01964703 Phase 4
11 Metformin and Longevity Genes in Prediabetes Completed NCT01765946 Phase 4
12 Evaluating the Effects of a Diet and Exercise Program in People With Type 2 Diabetes or Prediabetes: (The SHAPE3 Study) Completed NCT00928005 Phase 4
13 Oral Cholecalciferol in Prevention of Type 2 Diabetes Mellitus Completed NCT01436916 Phase 4
14 Effect of Anthocyanins on Metabolic Profiles in Subjects With Pre-diabetes Completed NCT02689765 Phase 4
15 Effects of Vitamin D on Beta Cell Function and Insulin Sensitivity in Pre-diabetes and Diabetes Mellitus Type 2 Completed NCT01497132 Phase 4
16 Evaluation of the Translation of the DE-PLAN Program for the Primary Prevention of Type 2 Diabetes in Routine Primary Care Completed NCT01365013 Phase 4
17 Reducing Risk of Type 2 Diabetes: Hydroxychloroquine Use in Pre-Diabetes Completed NCT01326533 Phase 4
18 Physical Exercise Versus Rosiglitazone in CAD and Prediabetes Completed NCT00675740 Phase 4
19 Acute Impact of Intramuscular (IM) Aripiprazole and Olanzapine on Insulin Resistance in High Risk Prediabetics Completed NCT01411930 Phase 4
20 The Effect of Vitamin K Supplementation on Glucose Metabolism Completed NCT00960973 Phase 4
21 Study to Determine the Effects of Human Growth Hormone and Pioglitazone in Overweight, Prediabetic Adults Completed NCT00352287 Phase 4
22 The Vascular Effects of Exenatide Versus Metformin in Patients With Pre-Diabetes Completed NCT00546728 Phase 4
23 Incretins in Impaired Fasting Glucose Completed NCT00364377 Phase 4
24 Mechanisms Underlying Metabolic Syndrome in Obesity Completed NCT00579813 Phase 4
25 The Effect of A-lipoic Acid (ALA) on Fatty Acid-induced Impairment of Glucose-stimulated Insulin Secretion Completed NCT01056497 Phase 4
26 The Study of Exenatide Action on Vessel Function in Type 2 Diabetes and Prediabetes Completed NCT01181986 Phase 4
27 Metformin and Corus CAD Completed NCT02440893 Phase 4
28 Metformin in Insulin Resistant Left Ventricular (LV) Dysfunction (TAYSIDE Trial) Completed NCT00473876 Phase 4
29 Niacin, N-3 Fatty Acids and Insulin Resistance Completed NCT00286234 Phase 4
30 University of Texas H.S.C. San Antonio Pioglitazone in Non-Alcoholic Steatohepatitis Trial (UTHSCSA NASH Trial) Completed NCT00994682 Phase 4
31 Treatment With Sitagliptin for Reactive Hypoglycemia Secondary to Dysinsulinism Completed NCT00847080 Phase 4
32 Sitagliptin Improved Beta Cell Function and Prevented a Conversion Rate to Impaired Glucose Tolerance and Type 2 Diabetes in Metformin Intolerant Obese Women With Polycystic Ovary Syndrome Completed NCT03122041 Phase 4
33 Tarka vs. Hyzaar in Patients With Metabolic Syndrome (STAR) Completed NCT00234858 Phase 4
34 The Effects of Vitamin D on Transforming Growth Factor-beta1 in Polycystic Ovary Syndrome Completed NCT02460380 Phase 4
35 Effect of Prolonged PDE-5 Inhibition on Insulin Signaling in Skeletal Muscle. Completed NCT02129725 Phase 4
36 Effect of 5 Years of GH Replacement on Atherosclerosis Completed NCT00462475 Phase 4
37 Metabolic Effects of Antihypertensive Drugs on People With Metabolic Syndrome (The MEAD Study) Completed NCT00887510 Phase 4
38 Switching From Zidovudine to an NNRTI or Lopinavir/Ritonavir in Patients Treated With Zidovudine/ Lamivudine/Abacavir. Completed NCT00139178 Phase 4
39 Free Fatty Acid-Induced Hypertension in Obese Subjects With Type 2 Diabetes Completed NCT00738023 Phase 4
40 Effect of Vitamin D Supplementation on Fasting Glucose and Interleukin-10 (IL-10) in Arab Women With Impaired Fasting Glucose Completed NCT00877123 Phase 4
41 Effect of Linagliptin + Metformin vs Metformin Alone in Patients With Prediabetes Recruiting NCT03004612 Phase 4
42 Coronary Artery Disease Progression in Patients With Prediabetes Recruiting NCT02744976 Phase 4
43 Effect of Berberine Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Prediabetes Recruiting NCT03029390 Phase 4
44 Improving Beta Cell Function in Mexican American Women With Prediabetes Recruiting NCT02488057 Phase 4
45 Effect of Pravastatin in the Subjects With Prediabetes or Early Diabetes Recruiting NCT02754739 Phase 4
46 Effect of Dapagliflozin on Blood Pressure Variability in Prediabetes and Prehypertension Recruiting NCT03006471 Phase 4
47 Dapagliflozin in Type 2 Diabetes or Pre-diabetes, and PRESERVED Ejection Fraction Heart Failure Recruiting NCT03030235 Phase 4
48 Development of Pre-pregnancy Intervention to Reduce the Risk of Diabetes and Prediabetes Recruiting NCT02617693 Phase 4
49 Metformin in Co-morbid Diabetes or Prediabetes and Serious Mental Illness Recruiting NCT02167620 Phase 4
50 Effect of Metadoxine on Oxidative Stress in Non-alcoholic Hepatic Steatosis Recruiting NCT02051842 Phase 4

Search NIH Clinical Center for Prediabetes Syndrome

Cochrane evidence based reviews: prediabetic state

Genetic Tests for Prediabetes Syndrome

Anatomical Context for Prediabetes Syndrome

MalaCards organs/tissues related to Prediabetes Syndrome:

39
Testes, Heart, Kidney

Publications for Prediabetes Syndrome

Articles related to Prediabetes Syndrome:

id Title Authors Year
1
Cardiovascular risk factors and the prediabetic syndrome. ( 8862692 )
1996

Variations for Prediabetes Syndrome

Expression for Prediabetes Syndrome

Search GEO for disease gene expression data for Prediabetes Syndrome.

Pathways for Prediabetes Syndrome

Pathways related to Prediabetes Syndrome according to GeneCards Suite gene sharing:

(show all 18)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.58 ADIPOQ IL6 INS LEP PRKAA2
2 12.3 ADIPOQ INS PPARG PRKAA2
3
Show member pathways
12.22 ADIPOQ INS LEP PPARG PRKAA2
4
Show member pathways
12.1 ALB APOB CRP IL6 INS
6
Show member pathways
11.94 ADIPOQ INS PPARG PRKAA2
7
Show member pathways
11.91 DPP4 INS LEP SLC30A8 TCF7L2
8
Show member pathways
11.89 IL6 INS PRKAA2
9 11.87 ALB IL6 INS
10
Show member pathways
11.76 IL6 INS PRKAA2
11 11.67 ADIPOQ IL6 INS LEP PPARG
12 11.56 INS PPARG PRKAA2
13 11.53 ADIPOQ LEP PRKAA2
14
Show member pathways
11.4 DPP4 LEP TCF7L2
15 11.34 ADIPOQ IL6 INS LEP PPARG
16 11.01 ADIPOQ LEP PPARG
17 10.84 CRP IL6
18 10.27 ADIPOQ IL6 LEP PPARG

GO Terms for Prediabetes Syndrome

Cellular components related to Prediabetes Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.76 ADIPOQ ALB APOB CRP DPP4 IL6
2 endosome lumen GO:0031904 9.26 APOB INS
3 endoplasmic reticulum lumen GO:0005788 9.26 ALB APOB IL6 INS
4 extracellular space GO:0005615 9.17 ADIPOQ ALB APOB CRP IL6 INS

Biological processes related to Prediabetes Syndrome according to GeneCards Suite gene sharing:

(show all 35)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.96 APOB CRP IL6 INS
2 response to drug GO:0042493 9.95 ADIPOQ GAD1 IL6 PPARG
3 cellular protein metabolic process GO:0044267 9.81 ALB APOB IL6 INS
4 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.78 ADIPOQ IL6 INS
5 cholesterol metabolic process GO:0008203 9.77 APOB LEP PRKAA2
6 positive regulation of MAPK cascade GO:0043410 9.76 IL6 INS LEP
7 response to nutrient GO:0007584 9.75 ADIPOQ LEP PPARG
8 response to glucose GO:0009749 9.72 ADIPOQ SLC30A8 TCF7L2
9 glucose metabolic process GO:0006006 9.7 ADIPOQ INS LEP
10 positive regulation of JAK-STAT cascade GO:0046427 9.67 IL6 LEP
11 cellular response to prostaglandin E stimulus GO:0071380 9.66 PPARG PRKAA2
12 positive regulation of cellular protein metabolic process GO:0032270 9.65 ADIPOQ INS
13 regulation of fat cell differentiation GO:0045598 9.65 LEP PPARG
14 fatty acid oxidation GO:0019395 9.64 ADIPOQ PPARG
15 lipoprotein transport GO:0042953 9.64 APOB PPARG
16 positive regulation of glycolytic process GO:0045821 9.63 INS PRKAA2
17 positive regulation of insulin receptor signaling pathway GO:0046628 9.63 INS LEP
18 response to nutrient levels GO:0031667 9.63 ADIPOQ IL6 LEP
19 locomotory exploration behavior GO:0035641 9.62 DPP4 GAD1
20 fatty acid homeostasis GO:0055089 9.62 INS PRKAA2
21 positive regulation of protein kinase B signaling GO:0051897 9.62 IL6 INS LEP TCF7L2
22 cellular response to nutrient levels GO:0031669 9.61 IL6 PRKAA2
23 negative regulation of hormone secretion GO:0046888 9.59 ADIPOQ IL6
24 response to caffeine GO:0031000 9.57 IL6 PPARG
25 regulation of fatty acid biosynthetic process GO:0042304 9.56 ADIPOQ PRKAA2
26 negative regulation of acute inflammatory response GO:0002674 9.54 INS PPARG
27 acute-phase response GO:0006953 9.54 CRP IL6 INS
28 negative regulation of collagen biosynthetic process GO:0032966 9.49 IL6 PPARG
29 negative regulation of vasodilation GO:0045908 9.48 CRP INS
30 positive regulation of STAT protein import into nucleus GO:2000366 9.43 IL6 LEP
31 negative regulation of gluconeogenesis GO:0045721 9.43 ADIPOQ IL6 INS
32 cellular response to prostaglandin stimulus GO:0071379 9.4 APOB PPARG
33 negative regulation of macrophage derived foam cell differentiation GO:0010745 9.33 ADIPOQ CRP PPARG
34 glucose homeostasis GO:0042593 9.23 ADIPOQ IL6 INS LEP PPARG PRKAA2
35 negative regulation of lipid storage GO:0010888 9.13 CRP IL6 LEP

Molecular functions related to Prediabetes Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.47 ADIPOQ ALB AMPD2 APOB COG2 CRP
2 low-density lipoprotein particle receptor binding GO:0050750 9.16 APOB CRP
3 hormone activity GO:0005179 9.13 ADIPOQ INS LEP

Sources for Prediabetes Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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