MCID: PRM013
MIFTS: 41

Premature Menopause malady

Categories: Reproductive diseases

Aliases & Classifications for Premature Menopause

Aliases & Descriptions for Premature Menopause:

Name: Premature Menopause 12 14 69
Menopause - Premature 12
Menopause, Premature 42
Menopause Premature 52
Menopause Praecox 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10787
ICD10 33 E28.31 E28.319
ICD9CM 35 256.31
MeSH 42 D008594
NCIt 47 C80099
UMLS 69 C0025322

Summaries for Premature Menopause

MalaCards based summary : Premature Menopause, also known as menopause - premature, is related to polyneuropathy mental retardation acromicria premature menopause and polyneuropathy-intellectual disability-acromicria-premature menopause syndrome. An important gene associated with Premature Menopause is BRCA1 (BRCA1, DNA Repair Associated), and among its related pathways/superpathways are Chks in Checkpoint Regulation and DNA Damage. The drugs Cyclophosphamide and Doxorubicin have been mentioned in the context of this disorder. Affiliated tissues include breast, bone and ovary, and related phenotypes are Decreased viability with cisplatin and Synthetic lethal with cisplatin

Related Diseases for Premature Menopause

Diseases related to Premature Menopause via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 84)
id Related Disease Score Top Affiliating Genes
1 polyneuropathy mental retardation acromicria premature menopause 12.1
2 polyneuropathy-intellectual disability-acromicria-premature menopause syndrome 12.0
3 premature ovarian failure 11.9
4 aorto-ventricular tunnel 10.3 BRCA1 BRCA2
5 burn scar 10.3 BRCA1 BRCA2
6 kunjin encephalitis 10.3 BRCA1 BRCA2
7 lethal congenital contracture syndrome 7 10.3 BRCA1 BRCA2
8 autoimmune disease of cardiovascular system 10.3 BRCA1 BRCA2
9 heart malignant hemangiopericytoma 10.3 BRCA1 BRCA2
10 bronchogenic cyst 10.3 BRCA1 BRCA2
11 lung clear cell-sugar-tumor 10.3 BRCA1 BRCA2
12 bronchiectasis oligospermia 10.3 BRCA1 BRCA2
13 chronic endophthalmitis 10.2 BRCA1 BRCA2
14 neuropathy, distal hereditary motor, type viib 10.2 BRCA1 BRCA2
15 breast pericanalicular fibroadenoma 10.2 BRCA1 BRCA2
16 eccrine sweat gland neoplasm 10.2 BRCA1 BRCA2
17 villoglandular endometrial endometrioid adenocarcinoma 10.2 BRCA1 BRCA2
18 paraphimosis 10.2 BRCA1 BRCA2
19 bladder colloid adenocarcinoma 10.2 BRCA1 BRCA2
20 bacteremia 10.2 BRCA1 BRCA2
21 syndromic x-linked intellectual disability 14 10.2 BRCA1 BRCA2
22 polyembryoma of the ovary 10.2 BRCA1 BRCA2
23 nemaline myopathy 8, autosomal recessive 10.2 BRCA1 BRCA2
24 mediastinum synovial sarcoma 10.2 BRCA1 BRCA2
25 fallopian tube carcinosarcoma 10.2 BRCA1 BRCA2
26 immunodeficiency due to a late component of complement deficiency 10.2 BRCA1 BRCA2
27 pneumonia 10.2 BRCA1 BRCA2
28 mycobacterium kansasii 10.2 BRCA1 BRCA2
29 estrogen-receptor positive breast cancer 10.2 BRCA1 BRCA2
30 pyomyositis 10.2 BRCA1 BRCA2
31 metagonimiasis 10.2 BRCA1 BRCA2
32 fibrous meningioma 10.2 TG TPO
33 neuhauser daly magnelli syndrome 10.2 TG TPO
34 premature closure of the arterial duct 10.2 TG TPO
35 background diabetic retinopathy 10.1 TG TPO
36 krabbe disease 10.1 TG TPO
37 nasal cavity adenocarcinoma 10.1 BRCA2 TG
38 tick paralysis 10.1 TG TPO
39 dental caries 10.1 BRCA1 BRCA2
40 conjunctival deposit 10.1 TG TPO
41 endemic goiter 10.1 TG TPO
42 mixed eosinophil-basophil adenoma 10.1 TG TPO
43 caudal regression syndrome 10.1 TG TPO
44 color blindness 10.1 TG TPO
45 hypothyroidism, congenital, nongoitrous, 1 10.1 TG TPO
46 nasal cavity disease 10.1 BRCA1 BRCA2
47 broad ligament malignant neoplasm 10.1 TG TPO
48 dysautonomia, familial 10.1 TG TPO
49 nodular prostate 10.1 TG TPO
50 exanthema subitum 10.1 TG TPO

Graphical network of the top 20 diseases related to Premature Menopause:



Diseases related to Premature Menopause

Symptoms & Phenotypes for Premature Menopause

GenomeRNAi Phenotypes related to Premature Menopause according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability with cisplatin GR00101-A-4 8.96 BRCA1 BRCA2
2 Synthetic lethal with cisplatin GR00101-A-1 8.62 BRCA1 BRCA2

MGI Mouse Phenotypes related to Premature Menopause:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.8 AMH BRCA1 BRCA2 POLG SYCE1 TG
2 homeostasis/metabolism MP:0005376 9.7 BRCA1 BRCA2 POLG SYCE1 TG TPO
3 neoplasm MP:0002006 9.26 AMH BRCA1 BRCA2 POLG
4 reproductive system MP:0005389 9.02 AMH BRCA1 BRCA2 POLG SYCE1

Drugs & Therapeutics for Premature Menopause

Drugs for Premature Menopause (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 186)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cyclophosphamide Approved, Investigational Phase 4,Phase 3,Phase 2 50-18-0, 6055-19-2 2907
2
Doxorubicin Approved, Investigational Phase 4,Phase 3 23214-92-8 31703
3
Progesterone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 57-83-0 5994
4
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 50-28-2 5757 53477783
5
Ethinyl Estradiol Approved Phase 4,Phase 3 57-63-6 5991
6
Norethindrone Approved Phase 4,Phase 2,Phase 3 68-22-4 6230
7
Ganirelix Approved Phase 4,Phase 2,Phase 3 123246-29-7, 124904-93-4 25081094
8
Cetrorelix Approved, Investigational Phase 4,Phase 2,Phase 3 120287-85-6 16129715 25074887
9
Menotropins Approved Phase 4 61489-71-2 5360545
10
Leuprolide Approved, Investigational Phase 4,Phase 2 53714-56-0 3911 657181
11
Lenograstim Approved Phase 4 135968-09-1
12
Doxil Approved June 1999 Phase 4,Phase 3 31703
13 Alkylating Agents Phase 4,Phase 3,Phase 2
14 Anti-Bacterial Agents Phase 4,Phase 3
15 Antibiotics, Antitubercular Phase 4,Phase 3
16 Antineoplastic Agents, Alkylating Phase 4,Phase 3,Phase 2
17 Antirheumatic Agents Phase 4,Phase 3,Phase 2
18 Immunosuppressive Agents Phase 4,Phase 3,Phase 2
19 Topoisomerase Inhibitors Phase 4,Phase 3
20 Estrogens Phase 4,Phase 3,Phase 2,Early Phase 1
21 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
22 Hormones Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
23 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
24 Follicle Stimulating Hormone Phase 4,Phase 1,Phase 2,Early Phase 1
25 Contraceptive Agents Phase 4,Phase 3,Phase 2
26 Contraceptives, Oral Phase 4,Phase 2,Phase 3
27 Estradiol 17 beta-cypionate Phase 4,Phase 3,Phase 2,Early Phase 1
28 Estradiol 3-benzoate Phase 4,Phase 3,Phase 2,Early Phase 1
29 Estradiol valerate Phase 4,Phase 3,Phase 2,Early Phase 1 979-32-8
30
Lactitol Phase 4 585-86-4 3871
31 Norethindrone acetate Phase 4,Phase 2,Phase 3
32 Norethindrone acetate, ethinyl estradiol, ferrous fumarate drug combination Phase 4
33 Norinyl Phase 4
34 Polyestradiol phosphate Phase 4,Phase 3,Phase 2,Early Phase 1
35 Progestins Phase 4,Phase 3,Phase 2,Early Phase 1
36 Chorionic Gonadotropin Phase 4
37 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2
38 Deslorelin Phase 4,Phase 2,Phase 3
39 Luteolytic Agents Phase 4,Phase 3,Phase 2
40 Triptorelin Pamoate Phase 4,Phase 3,Phase 2
41 Fertility Agents Phase 4,Phase 2
42
s 1 (combination) Phase 4
43 Adjuvants, Immunologic Phase 4,Phase 2,Phase 3,Early Phase 1
44
Goserelin Approved Phase 3 65807-02-5 47725 5311128
45
Epirubicin Approved Phase 3 56420-45-2 41867
46
Fluorouracil Approved Phase 3 51-21-8 3385
47
Methotrexate Approved Phase 3 1959-05-2, 59-05-2 126941
48
Paclitaxel Approved, Vet_approved Phase 3 33069-62-4 36314
49
Triamcinolone Approved, Vet_approved Phase 3 124-94-7 31307
50
Gabapentin Approved, Investigational Phase 3 60142-96-3 3446

Interventional clinical trials:

(show top 50) (show all 102)
id Name Status NCT ID Phase
1 Effects of ADSC Therapy in Women With POF Unknown status NCT01853501 Phase 4
2 Pharmacogenetics as a Predictor of Toxicity in Pre-Menopausal Women Receiving Doxorubicin and Cyclophosphamide in Early Breast Cancer Unknown status NCT00352872 Phase 4
3 Evaluation of Physiologic and Standard Sex Steroid Replacement Regimens in Women With Premature Ovarian Failure Completed NCT00732693 Phase 4
4 Modified Natural Cycle Offers a Chance of Pregnancy in Patients With Poor Response and High Basal FSH Completed NCT00417157 Phase 4
5 Flexible GnRH Antagonist vs Flare up GnRH Agonist Protocol in Poor Responders Completed NCT00417066 Phase 4
6 Estrogen Dosing in Turner Syndrome: Pharmacology and Metabolism Completed NCT00837616 Phase 4
7 A Study to Compare the Safety and Efficacy of Cetrotide® 3 Milligram (mg) Versus Antagon™ in Women Undergoing Ovarian Stimulation Completed NCT00298025 Phase 4
8 Randomized Controlled Trial Comparing Embryonic Quality in rFSH Versus hMG in IVF Protocol With GnRH Antagonist Completed NCT02412904 Phase 4
9 Filgrastim for Premature Ovarian Insufficiency Active, not recruiting NCT02783937 Phase 4
10 Effect of Cetrorelex Acetate on Ovarian Function in Women Undergoing Chemotherapy Withdrawn NCT00507780 Phase 4
11 Cognitive Behavioral Therapy (CBT) and Physical Exercise for Climacteric Symptoms in Breast Cancer Patients Experiencing Treatment-Induced Menopause: a Multicenter Randomized Trial Unknown status NCT00582244 Phase 3
12 Goserelin in Preventing Early Menopause in Premenopausal Women Undergoing Chemotherapy for Stage I, Stage II, or Stage III Breast Cancer Completed NCT00427245 Phase 3
13 Triptorelin in Preventing Early Menopause in Premenopausal Women Who Are Receiving Chemotherapy for Stage I, Stage II, or Stage III Breast Cancer That Has Been Removed By Surgery Completed NCT00311636 Phase 3
14 Efficiency of Gonadotropin-releasing Hormone (GnRH) Agonist in Preventing Chemotherapy Induced Ovarian Failure Completed NCT01160315 Phase 2, Phase 3
15 S0230 Goserelin in Preventing Ovarian Failure in Women Receiving Chemotherapy for Breast Cancer Completed NCT00068601 Phase 3
16 Estrogen Treatment (Oral vs. Patches) in Turner Syndrome Completed NCT00140998 Phase 3
17 Administration During Chemotherapy to Reduce Ovarian Failure Following Chemotherapy in Early Stage, Hormone-Receptor Negative Breast Cancer Completed NCT01530607 Phase 3
18 Pilot Study Comparing Hypnotherapy and Gabapentin for Hot Flashes. Completed NCT00711529 Phase 3
19 Combination Chemotherapy in Treating Young Patients With Hodgkin's Lymphoma Completed NCT00433459 Phase 3
20 Endometrial Injury and IVF Outcome Parameters in Patients With Failed IVF Cycles Completed NCT01798862 Phase 2, Phase 3
21 Hormone Replacement for Premature Ovarian Insufficiency Recruiting NCT02922348 Phase 3
22 Dehydroepiandrosterone (DHEA) Treatment and Premature Ovarian Failure (POF) Terminated NCT00948857 Phase 2, Phase 3
23 Effect of Exercise and Phytoestrogen on Bone, Metabolic Syndrome Criteria and Complaints of the Early Menopause Terminated NCT00663104 Phase 3
24 Goserelin Acetate Study for Ovarian Function in Patients With Primary Breast Cancer Terminated NCT00429403 Phase 3
25 Stem Cell Therapy Combined Hormone Replacement Therapy in Patients With Premature Ovarian Failure Unknown status NCT01742533 Phase 1, Phase 2
26 Autologous Mesenchymal Stem Cells Transplantation In Women With Premature Ovarian Failure Unknown status NCT02062931 Phase 1, Phase 2
27 Autologous Stem Cells Transplantation in Patients With Idiopathic and Drug Induced Premature Ovarian Failure Unknown status NCT02043743 Phase 1, Phase 2
28 Pregnancy After Stem Cell Transplantation in Premature Ovarian Failure Completed NCT02151890 Phase 1, Phase 2
29 Hormone Replacement in Young Women With Premature Ovarian Failure Completed NCT00001951 Phase 2
30 "It is a Real" The First Baby Of Autologous Stem Cell Therapy in Premature Ovarian Failure Completed NCT02372474 Phase 1, Phase 2
31 Bioidentical 'Natural' Hormone Evaluation in Early Menopause Completed NCT00302731 Phase 2
32 GnRH Analogue for Ovarian Function Preservation in Hematopoietic Stem Cell Transplantation Patients Completed NCT00429494 Phase 2
33 Red Blood Cell (RBC) Survival Following Transfusion in Infants Completed NCT00731588 Phase 2
34 Autologous Adipose Derived Mesenchymal Stromal Cells Transplantation in Women With Premature Ovarian Failure (POF) Recruiting NCT02603744 Phase 1, Phase 2
35 Transplantation of HUC-MSCs With Injectable Collagen Scaffold for POF Recruiting NCT02644447 Phase 1, Phase 2
36 Project 1, Study 2: Extended Exposure to Low Nicotine Content Cigarettes in Childbearing Age Women Recruiting NCT02250534 Phase 1, Phase 2
37 Autologous Bone Marrow-Derived Stem Cell Transplantation in Patients With Premature Ovarian Failure (POF) Active, not recruiting NCT03069209 Phase 1, Phase 2
38 Rituximab and Belimumab for Lupus Nephritis Active, not recruiting NCT02260934 Phase 2
39 Human Growth Hormone Pre-treatment for 6 Weeks Prior to Ovulation Induction for IVF Enrolling by invitation NCT02179255 Phase 1, Phase 2
40 Aromatase Inhibitors in Premenopausal Breast Cancer Patients With Chemotherapy-Induced Ovarian Failure Terminated NCT00555477 Phase 2
41 Use of a Calcium Channel Blocker to Prevent Premature Luteinizing Hormone Surges in Infertility Patients Terminated NCT01551368 Phase 2
42 Effects of an Estrogen Replacement Therapy Skin Patch on Ovulation in Women With Premature Ovarian Failure Withdrawn NCT00370019 Phase 2
43 The Role of Vitamin D in Menopause: Relationship to Menopausal Symptoms in Body Composition Completed NCT01141972 Phase 1
44 A Therapeutic Trial of Human Amniotic Epithelial Cells Transplantation for Primary Ovarian Insufficiency Patients Recruiting NCT02912104 Phase 1
45 Inovium Ovarian Rejuvenation Trials Not yet recruiting NCT03178695 Phase 1
46 Premature Ovarian Failure (Genetic and Physiopathologic Analysis) Unknown status NCT00780897
47 Inactive FSH in Galactosemia Unknown status NCT00619333
48 Perception and Attitude Toward Estrogen Therapy Among Surgically Menopausal Women Unknown status NCT00173550
49 In Vitro Activation of Dormant Follicles for Patients With Primary Ovarian Insufficiency Unknown status NCT02322060
50 'SPRING'-Study: "Subfertility Guidelines: Patient Related Implementation in the Netherlands Among Gynaecologists" Unknown status NCT00119925

Search NIH Clinical Center for Premature Menopause

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: menopause, premature

Genetic Tests for Premature Menopause

Anatomical Context for Premature Menopause

MalaCards organs/tissues related to Premature Menopause:

39
Breast, Bone, Ovary, Thyroid

Publications for Premature Menopause

Articles related to Premature Menopause:

(show top 50) (show all 118)
id Title Authors Year
1
Dealing with premature menopause in women at high-risk for hereditary genital and breast cancer. ( 26928421 )
2016
2
Prevention of Premature Menopause and Preservation of Fertility in Young Cancer Survivors: Hopeful Though Modest Long-term Results. ( 26720024 )
2015
3
Spanish consensus on premature menopause. ( 25578643 )
2015
4
Autosomal Translocation Patient Who Experienced Premature Menopause: A Case Report. ( 26356509 )
2015
5
Hormone treatment may help prevent premature menopause in cancer patients. ( 26702070 )
2015
6
Managing premature menopause and sexual dysfunction. ( 26155020 )
2015
7
Premature Menopause. ( 26316242 )
2015
8
Symptoms, health behavior and understanding of menopause therapy in women with premature menopause. ( 24742007 )
2014
9
Risk of premature menopause after treatment for Hodgkin's lymphoma. ( 25139688 )
2014
10
Risk of premature menopause after treatment for Hodgkin's lymphoma. ( 25139687 )
2014
11
Premature menopause - Meeting the needs. ( 24879744 )
2014
12
Impact of a premature menopause on cognitive function in later life. ( 24802975 )
2014
13
Premature menopause and risk of neurological disease: basic mechanisms and clinical implications. ( 24462786 )
2014
14
An interpretive description of chemotherapy-induced premature menopause among Latinas with breast cancer. ( 25158665 )
2014
15
Premature menopause. ( 23634337 )
2013
16
Frequency of premature menopause in women who carry a BRCA1 or BRCA2 mutation. ( 23414920 )
2013
17
Premature menopause in young breast cancer: effects on quality of life and treatment interventions. ( 23819028 )
2013
18
A nationwide study on reproductive function, ovarian reserve, and risk of premature menopause in female survivors of childhood cancer: design and methodological challenges. ( 22917040 )
2012
19
Psychosocial adjustment in women with premature menopause: a cross-sectional survey. ( 22335389 )
2012
20
Ovarian suppression for prevention of premature menopause and infertility: empty promise or effective therapy? ( 22231046 )
2012
21
Premature menopause or early menopause and risk of ischemic stroke. ( 21993082 )
2012
22
Premature menopause: a comprehensive understanding of psychosocial aspects. ( 21854296 )
2011
23
Premature menopause and severity of coronary artery disease. ( 22279478 )
2011
24
Hormone replacement therapy and women with premature menopause--a cancer survivorship issue. ( 21561765 )
2011
25
Menopause and sexuality: key issues in premature menopause and beyond. ( 20840281 )
2010
26
Premature menopause is associated with increased risk of cerebral infarction in Japanese women. ( 20042893 )
2010
27
Premature menopause linked to CVD and osteoporosis. ( 20408329 )
2010
28
Premature menopause or early menopause: long-term health consequences. ( 19733988 )
2010
29
The concept and treatment methodology for inducing ovulation in women in apparent premature menopause. ( 19688943 )
2009
30
Premature menopause: exploring the experience through online communication. ( 19298304 )
2009
31
Successful pregnancy with frozen embryo transfer into a gestational carrier from eggs obtained from a woman in premature menopause. ( 19860356 )
2009
32
Premature menopause increases cardiovascular risk. ( 19811237 )
2009
33
Treatment-related risk factors for premature menopause following Hodgkin lymphoma. ( 17890454 )
2008
34
Premature menopause: Hormone replacement therapy is indeed indicated. ( 18497386 )
2008
35
"Coming to grips" with chemotherapy-induced premature menopause. ( 18389434 )
2008
36
Ovulation induction and pregnancy in a woman with premature menopause following gonadotropin suppression with the gonadotropin releasing hormone antagonist, cetrorelix--a case report. ( 18404830 )
2008
37
Suspected premature menopause. ( 18403549 )
2008
38
HRT in premature menopause. ( 18796482 )
2008
39
Premature menopause: Article's recommendation of HRT is highly questionable. ( 18467384 )
2008
40
Management of premature menopause. ( 17448268 )
2007
41
Treatment of premature menopause in breast cancer patients. ( 17685250 )
2007
42
Effect of premature menopause on sexuality. ( 19804022 )
2007
43
Do survivors of childhood cancer have increased incidence of premature menopause? ( 17259929 )
2007
44
Reproductive and hormonal sequelae of chemotherapy in women. Premature menopause and impaired fertility can result, effects that are especially disturbing to young women. ( 16481857 )
2006
45
Premature menopause in survivors of childhood cancer: a report from the childhood cancer survivor study. ( 16818852 )
2006
46
Premature menopause in patients with BRCA1 gene mutation. ( 16773440 )
2006
47
Premature menopause in association with blepharophimosis, ptosis, and epicanthus inversus. ( 16147759 )
2005
48
Premature menopause: management challenges after the Women's Health Initiative. ( 16354460 )
2005
49
Maintenance of ovarian function and risk of premature menopause related to cancer treatment. ( 15784817 )
2005
50
Mechanisms of premature menopause. ( 16310631 )
2005

Variations for Premature Menopause

Expression for Premature Menopause

Search GEO for disease gene expression data for Premature Menopause.

Pathways for Premature Menopause

Pathways related to Premature Menopause according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.04 BRCA1 BRCA2 POLG
2 11.8 BRCA1 BRCA2 POLG
3
Show member pathways
11.6 BRCA1 BRCA2 SYCE1
4 9.4 TG TPO

GO Terms for Premature Menopause

Cellular components related to Premature Menopause according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 lateral element GO:0000800 8.62 BRCA1 BRCA2

Biological processes related to Premature Menopause according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 double-strand break repair GO:0006302 9.43 BRCA1 BRCA2
2 intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 9.4 BRCA1 BRCA2
3 DNA synthesis involved in DNA repair GO:0000731 9.37 BRCA1 BRCA2
4 response to gamma radiation GO:0010332 9.32 BRCA2 POLG
5 strand displacement GO:0000732 9.26 BRCA1 BRCA2
6 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 9.16 BRCA1 BRCA2
7 hormone biosynthetic process GO:0042446 8.96 TG TPO
8 chordate embryonic development GO:0043009 8.62 BRCA1 BRCA2

Sources for Premature Menopause

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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