MCID: PRM089
MIFTS: 12

Premature Ovarian Failure 3 malady

Genetic diseases, Rare diseases categories

Aliases & Classifications for Premature Ovarian Failure 3

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Premature Ovarian Failure 3, Aliases & Descriptions:

Name: Premature Ovarian Failure 3 45 10 22 60


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases, Rare diseases


External Ids:

OMIM45 608996

Summaries for Premature Ovarian Failure 3

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MalaCards based summary: Premature Ovarian Failure 3 is related to premature ovarian failure, and has symptoms including autosomal dominant inheritanceand premature ovarian failure. An important gene associated with Premature Ovarian Failure 3 is FOXL2 (forkhead box L2).

Description from OMIM:45 608996

Related Diseases for Premature Ovarian Failure 3

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Diseases in the Premature Ovarian Failure family:

Premature Ovarian Failure 9 Premature Ovarian Failure 6
premature ovarian failure 3 Premature Ovarian Failure 8
Premature Ovarian Failure 5 Premature Ovarian Failure 7
Premature Ovarian Failure 2b Premature Ovarian Failure 1
Premature Ovarian Failure, Familial

Diseases related to Premature Ovarian Failure 3 via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1premature ovarian failure10.4

Symptoms for Premature Ovarian Failure 3

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Clinical features from OMIM:

608996

HPO human phenotypes related to Premature Ovarian Failure 3:

id Description Frequency HPO Source Accession
1 autosomal dominant inheritance HP:0000006
2 premature ovarian failure HP:0008209

Drugs & Therapeutics for Premature Ovarian Failure 3

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Drug clinical trials:

Search ClinicalTrials for Premature Ovarian Failure 3

Search NIH Clinical Center for Premature Ovarian Failure 3

Genetic Tests for Premature Ovarian Failure 3

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Genetic tests related to Premature Ovarian Failure 3:

id Genetic test Affiliating Genes
1 Premature Ovarian Failure 322

Anatomical Context for Premature Ovarian Failure 3

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Animal Models for Premature Ovarian Failure 3 or affiliated genes

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Publications for Premature Ovarian Failure 3

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Articles related to Premature Ovarian Failure 3:

idTitleAuthorsYear
1
Premature ovarian failure 3 years after menarche in a 16-year-old girl following human papillomavirus vaccination. (23035167)
2012

Variations for Premature Ovarian Failure 3

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UniProtKB/Swiss-Prot genetic disease variations for Premature Ovarian Failure 3:

62
id Symbol AA change Variation ID SNP ID
1FOXL2p.Gly187AspVAR_015181
2FOXL2p.Tyr258AsnVAR_021204rs28937885

Clinvar genetic disease variations for Premature Ovarian Failure 3:

6
id Gene Variation Type Significance SNP ID Assembly Location
1FOXL2FOXL2, 30-BP DEL, NT898deletionPathogenic
2FOXL2NM_023067.3(FOXL2): c.772T> A (p.Tyr258Asn)single nucleotide variantPathogenicrs28937885GRCh37Chr 3, 138664793: 138664793
3FOXL2NM_023067.3(FOXL2): c.560G> A (p.Gly187Asp)single nucleotide variantPathogenicrs121908359GRCh37Chr 3, 138665005: 138665005

Expression for genes affiliated with Premature Ovarian Failure 3

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Search GEO for disease gene expression data for Premature Ovarian Failure 3.

Pathways for genes affiliated with Premature Ovarian Failure 3

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Compounds for genes affiliated with Premature Ovarian Failure 3

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GO Terms for genes affiliated with Premature Ovarian Failure 3

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Products for genes affiliated with Premature Ovarian Failure 3

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Premature Ovarian Failure 3

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet