MCID: PRM020
MIFTS: 44

Premenstrual Tension malady

Categories: Reproductive diseases

Aliases & Classifications for Premenstrual Tension

Aliases & Descriptions for Premenstrual Tension:

Name: Premenstrual Tension 12 14 69
Premenstrual Syndrome 42 69

Classifications:



External Ids:

Disease Ontology 12 DOID:727
ICD10 33 N94.3
ICD9CM 35 625.4
MeSH 42 D011293
UMLS 69 C0376356

Summaries for Premenstrual Tension

MalaCards based summary : Premenstrual Tension, also known as premenstrual syndrome, is related to distal monosomy 14q and hypogonadism mitral valve prolapse mental retardation, and has symptoms including pelvic pain, unspecified symptom associated with female genital organs and mittelschmerz. An important gene associated with Premenstrual Tension is GNRH1 (Gonadotropin Releasing Hormone 1), and among its related pathways/superpathways are Nongenotropic Androgen signaling and Glucocorticoid Pathway (HPA Axis), Pharmacodynamics. The drugs Estradiol and Guanfacine have been mentioned in the context of this disorder. Affiliated tissues include breast, and related phenotypes are homeostasis/metabolism and endocrine/exocrine gland

Related Diseases for Premenstrual Tension

Diseases related to Premenstrual Tension via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 98)
id Related Disease Score Top Affiliating Genes
1 distal monosomy 14q 10.3 POMC REN
2 hypogonadism mitral valve prolapse mental retardation 10.3 POMC REN
3 cystitis 10.3 FLCN GNRH1 PGR
4 macular retinal edema 10.3 AVP POMC
5 african histoplasmosis 10.3 GNRH1 POMC PRL
6 vertebral artery occlusion 10.3 GNRH1 POMC PRL
7 extragonadal nonseminomatous germ cell tumor 10.2 GNRH1 POMC PRL
8 olfactory nerve neoplasm 10.2 GNRH1 POMC PRL
9 glossopharyngeal nerve neoplasm 10.2 AVP POMC REN
10 malignant otitis externa 10.2 CRH POMC REN
11 bagassosis 10.2 AVP POMC
12 wheat allergy 10.2 PGR POMC PRL
13 pancreatic colloid cystadenoma 10.2 PGR POMC PRL
14 childhood optic tract astrocytoma 10.2 CRH POMC REN
15 hypogonadism cardiomyopathy 10.2 CRH POMC SHBG
16 skin sarcoma 10.2 PGR PRL
17 loeffler endocarditis 10.2 CRH POMC REN
18 haverhill fever 10.2 GNRH1 PGR PRL
19 nonparalytic poliomyelitis 10.2 CRH POMC PRL
20 endometriosis 10.2 GNRH1 PRL
21 hypermobility syndrome 10.2 CRH POMC REN
22 bile acid synthesis defect, congenital, 4 10.2 GNRH1 POMC PRL
23 dacryoadenitis 10.2 CRH POMC PRL
24 epidural spinal canal meningioma 10.2 GNRH1 PRL SHBG
25 infections, recurrent, with encephalopathy, hepatic dysfunction, and cardiovasuclar malformations 10.2 CRH POMC PRL
26 hemoglobin c disease 10.2 CRH HP PRL
27 adult i blood group with or without congenital cataract 10.2 CRH POMC PRL
28 gaucher's disease 10.2 GNRH1 PRL SHBG
29 bone benign neoplasm 10.2 AVP POMC PRL
30 endometrial mixed adenocarcinoma 10.2 POMC REN
31 congenital tricuspid stenosis 10.2 POMC PRL
32 acute thyroiditis 10.2 PGR PRL SHBG
33 retroperitoneal sarcoma 10.2 GNRH1 PRL SHBG
34 mucopolysaccharidosis type vi 10.2 AVP POMC PRL
35 vestibular gland benign neoplasm 10.2 POMC PRL REN
36 cervix squamous papilloma 10.2 CRH POMC PRL
37 aflatoxins-related hepatocellular carcinoma 10.2 POMC PRL SHBG
38 central nervous system vasculitis 10.2 KANTR REN
39 adamantinous craniopharyngioma 10.2 CRH POMC PRL
40 diverticulitis 10.2 GNRH1 PRL
41 intermittent squint 10.1 CRH GNRH1 POMC PRL
42 adrenal cortical adenocarcinoma 10.1 CRH GNRH1 POMC PRL
43 mechanical entropion 10.1 HP KANTR
44 sphingolipidosis 10.1 GNRH1 POMC PRL SHBG
45 pelvic muscle wasting 10.1 GNRH1 POMC PRL SHBG
46 indian tick typhus 10.1 MGAM POMC REN
47 kindler syndrome 10.1 AVP GNRH1 POMC PRL
48 merkel cell carcinoma 10.1 CRH POMC PRL REN
49 esophagus squamous cell papilloma 10.1 CRH POMC PRL REN
50 hemolytic anemia, cd59-mediated, with or without immune-mediated polyneuropathy 10.1 CRH POMC PRL

Graphical network of the top 20 diseases related to Premenstrual Tension:



Diseases related to Premenstrual Tension

Symptoms & Phenotypes for Premenstrual Tension

UMLS symptoms related to Premenstrual Tension:


pelvic pain, unspecified symptom associated with female genital organs, mittelschmerz, pain and other symptoms associated with female genital organs, other specified symptoms associated with female genital organs, female genital pain and other symptoms

MGI Mouse Phenotypes related to Premenstrual Tension:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.17 OXT PGR PNN POMC PRL REN
2 endocrine/exocrine gland MP:0005379 9.97 CRH GNRH1 LRP5 OXT PGR POMC
3 immune system MP:0005387 9.96 POMC PRL REN CAMP CRH FLCN
4 integument MP:0010771 9.76 CRH GNRH1 OXT PGR PNN POMC
5 neoplasm MP:0002006 9.43 FLCN GNRH1 HP PGR POMC PRL
6 renal/urinary system MP:0005367 9.23 AVP CRH FLCN GNRH1 HP OXT

Drugs & Therapeutics for Premenstrual Tension

Drugs for Premenstrual Tension (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 180)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-28-2 5757 53477783
2
Guanfacine Approved, Investigational Phase 4 29110-47-2 3519
3
Flutamide Approved Phase 4 13311-84-7 3397
4
Hydrocortisone Approved, Vet_approved Phase 4 50-23-7 5754 657311
5
Sumatriptan Approved, Investigational Phase 4,Phase 3 103628-46-2 5358
6
Drospirenone Approved Phase 4,Phase 3,Phase 2 67392-87-4 68873
7
Fluoxetine Approved, Vet_approved Phase 4,Phase 3 54910-89-3 3386
8
Naproxen Approved, Vet_approved Phase 4,Phase 3 22204-53-1 1302 156391
9
Desogestrel Approved Phase 4 54024-22-5 40973
10
Paroxetine Approved, Investigational Phase 4,Phase 3 61869-08-7 43815
11
Sertraline Approved Phase 4,Phase 1,Phase 2 79617-96-2 68617
12
Eletriptan Approved, Investigational Phase 4 143322-58-1 77993
13
Frovatriptan Approved, Investigational Phase 4 158747-02-5 77992
14
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
15
Ethinyl Estradiol Approved Phase 4,Phase 3,Phase 2 57-63-6 5991
16
Dinoprostone Approved Phase 4 363-24-6 5280360
17
Salmon Calcitonin Approved, Investigational Phase 4 47931-85-1 16129616
18
Citalopram Approved Phase 4 59729-33-8 2771
19 Progestins Phase 4,Phase 2
20 Estradiol valerate Phase 4,Phase 3,Phase 2,Phase 1 979-32-8
21 Analgesics Phase 4,Phase 3
22 Adrenergic Agents Phase 4
23 Adrenergic Agonists Phase 4
24 Adrenergic alpha-2 Receptor Agonists Phase 4
25 Adrenergic alpha-Agonists Phase 4
26 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1
27 Contraceptive Agents Phase 4,Phase 3,Phase 2
28 Contraceptives, Oral Phase 4,Phase 3,Phase 2
29 Analgesics, Non-Narcotic Phase 4,Phase 3
30 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
31 Hormones Phase 4,Phase 3,Phase 2,Phase 1
32 Diuretics, Potassium Sparing Phase 4,Phase 3,Phase 2
33 Peripheral Nervous System Agents Phase 4,Phase 3
34 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1
35 Estradiol 17 beta-cypionate Phase 4,Phase 3,Phase 2,Phase 1
36 Estradiol 3-benzoate Phase 4,Phase 3,Phase 2,Phase 1
37 Estrogens Phase 4,Phase 3,Phase 2,Phase 1
38 Polyestradiol phosphate Phase 4,Phase 3,Phase 2,Phase 1
39 Psychotropic Drugs Phase 4,Phase 3,Phase 1,Phase 2
40 Antihypertensive Agents Phase 4
41 Antineoplastic Agents, Hormonal Phase 4,Phase 2,Phase 3,Phase 1
42 Calcitonin Gene-Related Peptide Phase 4
43 calcitonin Phase 4
44 Tezosentan Phase 4
45 diuretics Phase 4,Phase 3,Phase 2
46
Serotonin Phase 4,Phase 3,Phase 1,Phase 2 50-67-9 5202
47 Serotonin 5-HT1 Receptor Agonists Phase 4,Phase 3
48 Serotonin Agents Phase 4,Phase 3,Phase 1,Phase 2
49 Serotonin Uptake Inhibitors Phase 4,Phase 3,Phase 1,Phase 2
50 Natriuretic Agents Phase 4,Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 105)
id Name Status NCT ID Phase
1 Prevention of Menstrual Migraines: Effects of Estrogen Add-back During the HFI in Patients Using Continuous Oral Contraceptives. Unknown status NCT01251263 Phase 4
2 Intuniv vs Placebo in the Treatment of Childhood Intermittent Explosive Disorder Unknown status NCT02048241 Phase 4
3 Short-Term Versus Long-Term Treatment for Severe Premenstrual Syndrome (PMS) Completed NCT00318773 Phase 4
4 Premenstrual Symptoms Treatment Comparing Between Oral Contraceptives Containing Desogestrel and Drospirenone Completed NCT01482338 Phase 4
5 Effectiveness of Flutamide in Treating Women With Premenstrual Dysphoric Disorder Completed NCT00611923 Phase 4
6 A Placebo-Controlled Study to Investigate the Onset of Action of Paroxetine in Premenstrual Dysphoria Completed NCT00516113 Phase 4
7 The Role of GABA and Neurosteroids in Premenstrual Dysphoric Disorder Completed NCT00678574 Phase 4
8 Evaluating the Effectiveness of Sertraline in Treating Women With Premenstrual Dysphoric Disorder Completed NCT00536198 Phase 4
9 An Investigation of the Safety and Utility of Treximet in the Treatment of Menstrual Migraine Completed NCT01578941 Phase 4
10 CGRP, Estrogen, Cortisol, VIP, α-Amylase, PGE2, PGI2 and ß-Endorphin Levels in Menstrual Migraine Before and After Treximet Completed NCT01329562 Phase 4
11 Prospective Survey of Menstrual Migraine & Prevention With Eletriptan Completed NCT00259649 Phase 4
12 Chances for Success of CavatermTM Surgery as a Function of Uterus Probe Length Completed NCT01436903 Phase 4
13 Effectiveness And Safety Of Frovatriptan For The Management (Acute Treatment) Of Menstrual Migraine Completed NCT00904098 Phase 4
14 Continuous Oral Contraceptive Treatment in Premenstrual Dysphoric Disorder (PMDD) Completed NCT00927095 Phase 4
15 Athena Pelvic Muscle Trainer - DUETS Trial Completed NCT01073878 Phase 4
16 Atomoxetine, Placebo and Parent Management Training in Autism Completed NCT00844753 Phase 4
17 Ultrasound Plus Nerve Stimulator Versus Nerve Stimulator Guided Lumbar Plexus Block Completed NCT02020096 Phase 4
18 Outcome of Percutaneous Mechanical Thrombectomy to Treat Acute Deep Venous Thrombosis Recruiting NCT02959801 Phase 4
19 Escitalopram for Premenstrual Syndrome (PMS) in Teens: A Pilot Study Terminated NCT00523705 Phase 4
20 Homeopathic Treatment of Premenstrual Syndrome Unknown status NCT02402049 Phase 3
21 GAMALINE®+HIPERICIN® for PMS Treatment and Vasomotor Symptoms Unknown status NCT01365676 Phase 3
22 Understanding Experimentally Induced Hot Flushes Unknown status NCT00455689 Phase 2, Phase 3
23 Comparison Between Oral Contraceptive Pills and Calcium Supplements in Treatment of Premenstrual Syndrome Completed NCT02089620 Phase 3
24 Dose-dependent Effects of VAC BNO 1095 on Cyclic Mastodynia and Premenstrual Syndrome Completed NCT01309113 Phase 3
25 Study Evaluating Combination of Levonorgestrel (LNG) and Ethinyl Estradiol (EE) in Premenstrual Dysphoric Disorder Completed NCT00128934 Phase 3
26 Study Evaluating Levonorgestrel/Ethinyl Estradiol (LNG/EE) in PMS Completed NCT00161681 Phase 3
27 Study Evaluating Combination of Levonorgestrel and Ethinyl Estradiol in Pre-Menstrual Dysphoric Disorder Completed NCT00195559 Phase 3
28 The Effect of Toremifene Treatment to the Magnetic Resonance Imaging (MRI) Findings in Premenstrual Mastalgia Completed NCT00534846 Phase 3
29 Treximet (Sumatriptan/Naproxen Sodium), Formerly Known as TREXIMA, for Menstrual Migraine in Women With Dysmenorrhea Completed NCT00329459 Phase 3
30 Menstrual Migraine Treatment With TREXIMET (Formerly Known as TREXIMA) Completed NCT00329355 Phase 3
31 Clinical Research Study to Evaluate Selegiline in the Treatment of Borderline Personality Disorder Completed NCT01912391 Phase 3
32 Diindolylmethane in Treating Patients With Abnormal Cervical Cells Completed NCT00462813 Phase 3
33 YAZ Premenstrual Dysphoric Disorder (PMDD) in China Completed NCT00824187 Phase 3
34 Luteal Phase Administration of Paroxetine for the Treatment of PMDD Completed NCT00620581 Phase 3
35 Operations and Pelvic Muscle Training in the Management of Apical Support Loss: The OPTIMAL Trial Completed NCT00597935 Phase 3
36 Dienogest Versus Luteal Phase Fluoxetine in the Management of Premenstrual Syndrome Recruiting NCT02427334 Phase 3
37 Combined Oral Contraceptives and Fluoxetine Versus Combined Oral Contraceptives in Severe Premenstrual Syndrome Recruiting NCT02488538 Phase 3
38 Does Adding Oral Contraceptives to Fluoxetine Improve the Management of Premenstrual Syndrome? Recruiting NCT02562053 Phase 3
39 Emotional Processing and Oxytocin Mechanisms in Premenstrual Dysphoric Disorder: A Pilot Study Active, not recruiting NCT02508103 Phase 2, Phase 3
40 Intranasal PH80 Spray for Acute Management of the Symptoms of Premenstrual Dysphoric Disorder Not yet recruiting NCT01217775 Phase 3
41 Efficacy and Safety of 20 mg (2 Tablets of 10mg)VAC BNO 1095 FCT on Cyclic Mastodynia and PMS Terminated NCT01870687 Phase 3
42 Evaluation of Safety/Efficacy of Diagnostic Skin Test Panel and Desensitization Hormone Kit for Treatment of Premenstrual Syndrome (PMS) Unknown status NCT00873262 Phase 2
43 Evaluation of Efficacy/Safety of EVE-PMS Skin Test Panel Unknown status NCT00866437 Phase 2
44 Auriculotherapy in the Cares to the Premenstrual Syndrome Completed NCT01782040 Phase 2
45 Antidepressant Treatment for Premenstrual Syndrome and Premenstrual Dysphoric Disorder Completed NCT00048854 Phase 1, Phase 2
46 The Effect of Individualised Homoeopathic Treatment Using the Grant Bentley Method in Premenstrual Syndrome Completed NCT02481973 Phase 2
47 An Observational Study on the Efficacy of Individualised Homoeopathic Treatment on Premenstrual Syndrome Completed NCT02467088 Phase 2
48 a Clinical Trial to Evaluate the Efficacy and Safety of Agnucaston Tablets in the Treatment of Premenstrual Syndrome (PMS) Completed NCT00672607 Phase 2
49 Role of Ginkgo Biloba Extract in IUGR Completed NCT02425436 Phase 2
50 A Phase I/II Study to Evaluate UC1010 Treatment in Premenstrual Dysphoric Disorder (PMDD) Completed NCT01875718 Phase 1, Phase 2

Search NIH Clinical Center for Premenstrual Tension

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: premenstrual syndrome

Genetic Tests for Premenstrual Tension

Anatomical Context for Premenstrual Tension

MalaCards organs/tissues related to Premenstrual Tension:

39
Breast

Publications for Premenstrual Tension

Articles related to Premenstrual Tension:

(show top 50) (show all 202)
id Title Authors Year
1
The premenstrual tension syndrome rating scales: an updated version. ( 21802738 )
2011
2
Characterization of headaches in the premenstrual tension syndrome. ( 19330208 )
2009
3
Role of bromocriptine and pyridoxine in premenstrual tension syndrome. ( 18476391 )
2007
4
Cerazette for premenstrual tension. ( 16105314 )
2005
5
A psychoanalytical approach to premenstrual tension syndrome. ( 15194524 )
2004
6
Historical studies of premenstrual tension up to 30 years ago: implications for future research. ( 12441020 )
2002
7
Women's perceptions of phenomena they label premenstrual tension: normal experiences reflecting ordinary behaviour. ( 10520105 )
1999
8
Relationship between premenstrual tension syndrome and anxiety in Chinese adolescents. ( 9502014 )
1998
9
Treatment of premenstrual tension syndrome with Vitex agnus castus controlled, double-blind study versus pyridoxine. ( 23195474 )
1997
10
Premenstrual tension among hysterectomized women. ( 8528381 )
1995
11
Plasma copper, zinc and magnesium levels in patients with premenstrual tension syndrome. ( 8042455 )
1994
12
Ovarian suppression with the gonadotrophin-releasing hormone agonist goserelin (Zoladex) in management of the premenstrual tension syndrome. ( 7962376 )
1994
13
Premenstrual tension among nurses in Nairobi, Kenya. ( 8306911 )
1993
14
Premenstrual tension as mitigation in a criminal case. ( 1431801 )
1992
15
Premenstrual tension syndrome with periodic bulimia nervosa: report of a case and review of the literature. ( 1360302 )
1992
16
Premenstrual tension: a placebo-controlled efficacy study with spironolactone and medroxyprogesterone acetate. ( 1673942 )
1991
17
Pre-eclampsia, hypertension and the premenstrual tension syndrome. ( 1972097 )
1990
18
Danazol, premenstrual tension, and uveitis. Case report. ( 2730393 )
1989
19
Assessment of the significance and severity of premenstrual tension--II. Comparison of methods. ( 2795504 )
1989
20
Assessment of the significance and severity of premenstrual tension--I. A new model. ( 2795503 )
1989
21
Induced anovulation as treatment of premenstrual tension syndrome. A double-blind cross-over study with GnRH-agonist versus placebo. ( 3140572 )
1988
22
Impaired reception of nonverbal cues in women with premenstrual tension syndrome. ( 3230535 )
1988
23
Plasma beta-endorphin immunoreactivity in premenstrual tension. ( 2949774 )
1987
24
Role of nutrition in managing the premenstrual tension syndromes. ( 2956416 )
1987
25
Platelet serotonin uptake and effects of vitamin B6-treatment in premenstrual tension. ( 3330183 )
1987
26
A clinical trial using danazol for the treatment of premenstrual tension. ( 3545282 )
1987
27
Premenstrual tension syndrome symptom clusters. Statistical evaluation of the subsyndromes. ( 3612634 )
1987
28
Vitamin B6 (pyridoxine) and the premenstrual tension syndrome. ( 3454904 )
1987
29
The premenstrual tension syndromes: an update. ( 3612633 )
1987
30
Evaluation of psychiatric symptoms in patients presenting with symptoms of premenstrual tension syndrome. ( 3301138 )
1987
31
Diagnosing premenstrual tension syndrome. ( 3943794 )
1986
32
Premenstrual tension syndrome in rapid-cycling bipolar affective disorder. ( 2874129 )
1986
33
Premenstrual tension, expectancy, and mother-child relations. ( 3746897 )
1986
34
Comparison of depressed and nondepressed women with severe premenstrual tension syndrome. ( 3823355 )
1986
35
Biochemical hypotheses of premenstrual tension syndrome. ( 2859626 )
1985
36
No effect of vitamin B-6 against premenstrual tension. A controlled clinical study. ( 3914180 )
1985
37
Pseudocholinesterase and trait anxiety in premenstrual tension syndrome. ( 4038979 )
1985
38
Hyperphagia in premenstrual tension syndrome. ( 2931423 )
1985
39
Cyclical mood changes as in the premenstrual tension syndrome during sequential estrogen-progestagen postmenopausal replacement therapy. ( 4061059 )
1985
40
Premenstrual tension syndrome. ( 3920591 )
1985
41
Hormonal studies in women with premenstrual tension. ( 4038882 )
1985
42
Premenstrual tension syndrome. ( 3906055 )
1985
43
Prolonged follicular phase and depressed gonadotrophins following hysterectomy and corpus lute-ectomy in women with premenstrual tension syndrome. ( 3926350 )
1985
44
Progesterone treatment of premenstrual tension--a double blind study. ( 3906106 )
1985
45
Premenstrual tension. ( 6542351 )
1984
46
beta-Endorphin withdrawal: a possible cause of premenstrual tension syndrome. ( 6094401 )
1984
47
A psychoendocrine study of premenstrual tension syndrome. A model for endogenous depression? ( 6233351 )
1984
48
Plasma prolactin and severe premenstrual tension. ( 6539925 )
1984
49
Premenstrual tension and dysmenorrhoea. ( 6538256 )
1984
50
Premenstrual tension. ( 6541695 )
1984

Variations for Premenstrual Tension

Expression for Premenstrual Tension

Search GEO for disease gene expression data for Premenstrual Tension.

Pathways for Premenstrual Tension

Pathways related to Premenstrual Tension according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.21 GNRH1 SHBG
2 9.47 CRH POMC

GO Terms for Premenstrual Tension

Cellular components related to Premenstrual Tension according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.76 AVP CAMP CRH GNRH1 HP OXT
2 extracellular region GO:0005576 9.4 AVP CAMP CRH GNRH1 HP LIPN
3 secretory granule GO:0030141 9.26 AVP OXT POMC PRL

Biological processes related to Premenstrual Tension according to GeneCards Suite gene sharing:

(show all 16)
id Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 9.86 AVP GNRH1 PGR POMC
2 regulation of blood pressure GO:0008217 9.67 LRP5 POMC REN
3 response to peptide hormone GO:0043434 9.58 GNRH1 LRP5 OXT
4 response to organic cyclic compound GO:0014070 9.56 AVP GNRH1 OXT PRL
5 maternal behavior GO:0042711 9.55 AVP OXT
6 grooming behavior GO:0007625 9.54 AVP OXT
7 parturition GO:0007567 9.52 CRH PRL
8 ovulation cycle GO:0042698 9.51 GNRH1 PRL
9 response to prostaglandin E GO:0034695 9.48 GNRH1 OXT
10 hyperosmotic salinity response GO:0042538 9.46 AVP OXT
11 response to ethanol GO:0045471 9.46 AVP CRH GNRH1 PRL
12 drinking behavior GO:0042756 9.43 OXT REN
13 positive regulation of cell proliferation GO:0008284 9.43 AVP CAMP CRH LRP5 PRL SP6
14 response to ether GO:0045472 9.37 CRH OXT
15 maternal aggressive behavior GO:0002125 9.32 AVP OXT
16 female pregnancy GO:0007565 8.92 CRH GNRH1 OXT PRL

Molecular functions related to Premenstrual Tension according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 neuropeptide hormone activity GO:0005184 9.33 AVP CRH OXT
2 hormone activity GO:0005179 9.1 AVP CRH GNRH1 OXT POMC PRL
3 neurohypophyseal hormone activity GO:0005185 8.96 AVP OXT

Sources for Premenstrual Tension

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
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42 MeSH
43 MESH via Orphanet
44 MGI
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48 NDF-RT
51 NINDS
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54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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