MCID: PRS025
MIFTS: 26

Presbyopia malady

Eye category

Summaries for Presbyopia

Sources:
64Wikipedia, 33MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:64 Presbyopia is a condition where, with age, the eye exhibits a progressively diminished ability to focus... more...

MalaCards: Presbyopia is related to astigmatism and hyperopia. An important gene associated with Presbyopia is CRYAA (crystallin, alpha A), and among its related pathways is Non-integrin membrane-ECM interactions. Affiliated tissues include cortex.

Aliases & Classifications for Presbyopia

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 27ICD9CM, 57SNOMED-CT, 35MeSH, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye


Aliases & Descriptions:

presbyopia 8 10 61


External Ids:

Disease Ontology8 DOID:11638
ICD9CM27 367.4
SNOMED-CT57 41256004, 155135005
MeSH35 D011305
ICD1025 H52.4

Related Diseases for Presbyopia

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Presbyopia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 13)
idRelated DiseaseScoreTop Affiliating Genes
1astigmatism10.4
2hyperopia10.4
3alternating exotropia10.0
4monofixation syndrome10.0
5amyloidosis10.0
6strabismus10.0
7cataract 1910.0
8cataract10.0CRYAA
9epidermolysis bullosa10.0LAMA3
10senile cataract10.0LAMA3, CRYAA
11dermatomyositis10.0FBN1
12glaucoma10.0LAMA3, FBN1
13myopia 610.0LAMA3, FBN1

Graphical network of diseases related to Presbyopia:



Diseases related to presbyopia

Clinical Features for Presbyopia

Drugs & Therapeutics for Presbyopia

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Presbyopia

Drug clinical trials:

Search ClinicalTrials for Presbyopia

Search NIH Clinical Center for Presbyopia

Search CenterWatch for Presbyopia

Genetic Tests for Presbyopia

Anatomical Context for Presbyopia

Sources:
33MalaCards
See all sources

MalaCards organs/tissues related to Presbyopia:

33
Cortex

Animal Models for Presbyopia or affiliated genes

Sources:
28inGenious Targeting Laboratory
See all sources

Publications for Presbyopia

Sources:
51PubMed
See all sources

Articles related to Presbyopia:

(show top 50)    (show all 351)
idTitleAuthorsYear
1
Combined hydrogel inlay and laser in situ keratomileusis to compensate for presbyopia in hyperopic patients: one-year safety and efficacy. (24021565)
2013
2
Corneal inlays for presbyopia correction. (23703461)
2013
3
Impact on stereo-acuity of two presbyopia correction approaches: monovision and small aperture inlay. (23761846)
2013
4
Femtosecond laser-assisted small-aperture corneal inlay implantation for corneal compensation of presbyopia: two-year follow-up. (23245507)
2013
5
Supraciliary contraction segments: A new method for the treatment of presbyopia. (23552349)
2013
6
Intraocular lenses for presbyopia correction: past, present, and future. (22081027)
2012
7
Cataract surgery after previous femtosecond laser intrastromal presbyopia treatment. (22727300)
2012
8
Visual function through 4 contact lens-based pinhole systems for presbyopia. (22424803)
2012
9
Small-aperture contact lenses for presbyopia. (23079328)
2012
10
Visual outcomes of LASIK-induced monovision in myopic patients with presbyopia. (21335110)
2011
11
Aspheric wavefront-guided LASIK to treat hyperopic presbyopia: 12-month results with the VISX platform. (21410083)
2011
12
Reading performance after implantation of a small-aperture corneal inlay for the surgical correction of presbyopia: Two-year follow-up. (21262559)
2011
13
Model of accommodation: contributions of lens geometry and mechanical properties to the development of presbyopia. (21029906)
2010
14
Flexibility and presbyopia intraocular lenses. (21036207)
2010
15
IOL Tetraflex, KH 3500--presbyopia treatment. (20361654)
2009
16
Presbyopia treatment by monocular peripheral presbyLASIK. (19603619)
2009
17
Photopic pupillometry-guided laser in situ keratomileusis for hyperopic presbyopia. (18242441)
2008
18
Contact lens correction of presbyopia. (18201225)
2008
19
Multifocal IOL technology: a successful step on the journey toward presbyopia treatment. (19027536)
2008
20
Anterior ciliary sclerotomy using collagen T-shaped implants for treatment of presbyopia. (19230348)
2008
21
The eye in focus: accommodation and presbyopia. (18336584)
2008
22
Analysis of the optical performance of presbyopia treatments with the defocus transfer function. (18041255)
2007
23
Correction of presbyopia by technovision central multifocal LASIK (presbyLASIK). (16722483)
2006
24
Impact of presbyopia on quality of life in a rural African setting. (16650665)
2006
25
Optical surface optimization for the correction of presbyopia. (16761062)
2006
26
Effectiveness of multifocal intraocular lenses to correct presbyopia after cataract surgery: a randomized controlled trial. (15465543)
2004
27
Surgical treatment of presbyopia: scleral, corneal, and lenticular. (15232478)
2004
28
Myopic astigmatism and presbyopia trial. (12719069)
2003
29
Management of presbyopia with soft contact lenses. (12207121)
2002
30
Implantation of scleral expansion band segments for the treatment of presbyopia. (12470747)
2002
31
Scleral expansion bands for presbyopia. (11733253)
2001
32
The surgical reversal of presbyopia: a new procedure to restore accommodation. (11290927)
2001
33
Anterior ciliary sclerotomy with silicone expansion plug implantation: effect on presbyopia and intraocular pressure. (11290928)
2001
34
Monofixation syndrome. Presbyopia monovision followup. (11093080)
2000
35
Peer review; cursing presbyopia; DUI and dealing with the law; Cadillac II: Robocop. (11093097)
2000
36
Scleral expansion surgery does not restore accommodation in human presbyopia. (10504089)
1999
37
Accommodation and presbyopia in the human eye. Changes in the anterior segment and crystalline lens with focus. (9071209)
1997
38
The AC/A ratio, age and presbyopia. (9390375)
1997
39
Monovision therapy in patients with presbyopia and binocular diplopia. (9258243)
1997
40
Validity of surveys reporting myopia, astigmatism, and presbyopia. (8807648)
1996
41
Presbyopia and velocity of sound in the lens. (8047337)
1994
42
The management of presbyopia with contact lenses: a review. (2407378)
1990
43
Correction of presbyopia with contact lenses: comparative success rates with three systems. (2771342)
1989
44
Presbyopia. (3056352)
1988
45
Correction of presbyopia with contact lenses and management of posterior capsule after cataract extraction. Adapted from the January 13, 1985 meeting of the Contact Lens Association of Ophthalmologists (CLAO). (4042316)
1985
46
Presbyopia in Nigerians. (6671438)
1983
47
Early onset of presbyopia. (7158649)
1982
48
The control of presbyopia without bifocals. (1027810)
1976
49
Further data on presbyopia in different ethnic groups. (5244428)
1968
50
The course of presbyopia in several South African ethnic groups. (13964001)
1963

Genetic Variations for Presbyopia

Expression for genes affiliated with Presbyopia

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Presbyopia

Search GEO for disease gene expression data for Presbyopia.

Pathways for genes affiliated with Presbyopia

Sources:
54Reactome, 30KEGG
See all sources

Pathways related to Presbyopia according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.5LAMA3, FBN1

Compounds for genes affiliated with Presbyopia

GO Terms for genes affiliated with Presbyopia

Sources:
16Gene Ontology
See all sources

Cellular components related to Presbyopia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1basement membraneGO:0056049.2LAMA3, FBN1
2extracellular spaceGO:0056158.5LEFTY1, FBN1, UCN2

Biological processes related to Presbyopia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of gene expressionGO:0106299.4CRYAA, UCN2

Products for genes affiliated with Presbyopia

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Presbyopia

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet