MCID: PRS025
MIFTS: 30

Presbyopia malady

Eye diseases category

Summaries for Presbyopia

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Sources:
66Wikipedia, 34MalaCards
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Wikipedia:66 Presbyopia is a condition where, with age, the eye exhibits a progressively diminished ability to focus... more...

MalaCards: Presbyopia is related to refractive error and cataract. An important gene associated with Presbyopia is CRYAA (crystallin, alpha A). Affiliated tissues include eye, testes and cortex, and related mouse phenotype cellular.

Aliases & Classifications for Presbyopia

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Sources:
9Disease Ontology, 11DISEASES, 63UMLS, 59SNOMED-CT, 36MeSH, 28ICD9CM, 26ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases


Aliases & Descriptions:

presbyopia 9 11 63


External Ids:

Disease Ontology9 DOID:11638
MeSH36 D011305
SNOMED-CT59 155135005, 41256004
ICD9CM28 367.4
ICD1026 H52.4

Related Diseases for Presbyopia

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Sources:
18GeneCards, 19GeneDecks
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Diseases related to Presbyopia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 14)
idRelated DiseaseScoreTop Affiliating Genes
1refractive error10.5
2cataract10.5
3astigmatism10.4
4myopia10.4
5hyperopia10.4
6retinitis10.1
7alternating exotropia10.0
8monofixation syndrome10.0
9cycloplegia10.0
10amyloidosis10.0
11esotropia10.0
12exotropia10.0
13eye disease10.0
14strabismus10.0

Graphical network of diseases related to Presbyopia:



Diseases related to presbyopia

Symptoms for Presbyopia

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Drugs & Therapeutics for Presbyopia

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Presbyopia

Search CenterWatch for Presbyopia

Genetic Tests for Presbyopia

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Anatomical Context for Presbyopia

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Sources:
34MalaCards
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MalaCards organs/tissues related to Presbyopia:

34
Eye, Testes, Cortex

Animal Models for Presbyopia or affiliated genes

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Sources:
38MGI
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MGI Mouse Phenotypes related to Presbyopia:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053849.1CRYAA, HIVEP3

Publications for Presbyopia

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Sources:
53PubMed
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Articles related to Presbyopia:

(show top 50)    (show all 346)
idTitleAuthorsYear
1
Prevalence of presbyopia and spectacle coverage in an African population in Durban, South Africa. (24162892)
2013
2
Presbyopia, spectacles use and spectacle correction coverage for near vision among cloth weaving communities in Prakasam district in South India. (23758169)
2013
3
Combined hydrogel inlay and laser in situ keratomileusis to compensate for presbyopia in hyperopic patients: one-year safety and efficacy. (24021565)
2013
4
Reading performance after implantation of a modified corneal inlay design for the surgical correction of presbyopia: 1-year follow-up. (22105801)
2012
5
Pig lenses in a lens stretcher: implications for presbyopia treatment. (22561204)
2012
6
Impact of corneal aberrations on through-focus image quality of presbyopia-correcting intraocular lenses using an adaptive optics bench system. (22902188)
2012
7
Meta-analysis of sex differences in presbyopia. (22531698)
2012
8
Objective evaluation of through-focus optical performance of presbyopia-correcting intraocular lenses using an optical bench system. (21700107)
2011
9
Strehl ratios characterizing optical elements designed for presbyopia compensation. (21643121)
2011
10
Presbyopia and cataract: a question of heat and time. (20472092)
2010
11
Spectacle independence and subjective satisfaction of ReSTOR multifocal intraocular lens after cataract or presbyopia surgery in two European countries. (20234773)
2010
12
Prandial presbyopia. (20182206)
2010
13
IOL Tetraflex, KH 3500--presbyopia treatment. (20361654)
2009
14
Uncorrected refractive errors, presbyopia and spectacle coverage: results from a rapid assessment of refractive error survey. (19874105)
2009
15
Performance of presbyopia-correcting intraocular lenses in distance optical bench tests. (19101440)
2009
16
LASIK for hyperopic astigmatism and presbyopia using micro-monovision with the Carl Zeiss Meditec MEL80 platform. (19244952)
2009
17
Presbyopia correcting intraocular lenses: what do I do? (18358849)
2008
18
Equatorial lens growth predicts the age-related decline in accommodative amplitude that results in presbyopia and the increase in intraocular pressure that occurs with age. (18209552)
2008
19
Presbyopia-correcting intraocular lenses: what retinal surgeons should know. (18398353)
2008
20
Photopic pupillometry-guided laser in situ keratomileusis for hyperopic presbyopia. (18242441)
2008
21
Progress in the spectacle correction of presbyopia. Part 1: Design and development of progressive lenses. (18279415)
2008
22
Analysis of the optical performance of presbyopia treatments with the defocus transfer function. (18041255)
2007
23
Presbyopia correction: managing the complex patient. (17984496)
2007
24
Uncorrected refractive error and presbyopia: accommodating the unmet need. (17576703)
2007
25
Traditional methods for the treatment of presbyopia: spectacles, contact lenses, bifocal contact lenses. (16500526)
2006
26
Presbyopia: perspective on the reality of pseudoaccommodation with LASIK. (16500528)
2006
27
Correction of presbyopia by technovision central multifocal LASIK (presbyLASIK). (16722483)
2006
28
Evidence for delayed presbyopia after photorefractive keratectomy for myopia. (16650666)
2006
29
A population-based assessment of presbyopia in the state of Andhra Pradesh, south India: the Andhra Pradesh Eye Disease Study. (16723440)
2006
30
Optics of conductive keratoplasty: implications for presbyopia management. (17057812)
2005
31
Multifocal IOLs for presbyopia. (16105572)
2005
32
Presbyopia case study. Eye series-20. (15532161)
2004
33
The effects of wearing corrective lenses for presbyopia on distance vision. (12535052)
2003
34
Regarding the surgical reversal of presbyopia (SRP) surgery for presbyopia, vol 108, number 12, December 2001, 2161-2. (12750070)
2003
35
Epidemiology of refractive errors and presbyopia. (14499819)
2003
36
The effect of incipient presbyopia on the correspondence between accommodation and vergence. (12107517)
2002
37
Presbyopia, accommodation, and mature catenary. (12153788)
2002
38
Presbyopia, accommodation, and mature catenary. (12153783)
2002
39
Management of presbyopia with soft contact lenses. (12207121)
2002
40
Aging of the human crystalline lens and presbyopia. (11290918)
2001
41
Monofixation syndrome. Presbyopia monovision followup. (11093080)
2000
42
Zonal photorefractive keratectomy for presbyopia. (9571559)
1998
43
Accommodation and presbyopia in the human eye. Changes in the anterior segment and crystalline lens with focus. (9071209)
1997
44
Induced hyperphoria in anisometropic presbyopia. (1814999)
1991
45
The management of presbyopia with contact lenses: a review. (2407378)
1990
46
Peripheral visual acuity with monovision and other contact lens corrections for presbyopia. (2771322)
1989
47
Monovision and related techniques in the management of presbyopia. (3449300)
1987
48
Forced vergence fixation disparity curves in presbyopia. (3789080)
1986
49
In and out of office communication for more efficient care (presbyopia). (6841880)
1983
50
PRESBYOPIA. (18170829)
1962

Variations for Presbyopia

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Expression for genes affiliated with Presbyopia

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Presbyopia

Search GEO for disease gene expression data for Presbyopia.

Pathways for genes affiliated with Presbyopia

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Compounds for genes affiliated with Presbyopia

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GO Terms for genes affiliated with Presbyopia

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17Gene Ontology
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Cellular components related to Presbyopia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cytoplasmGO:0057379.1CRYAA, HIVEP3

Molecular functions related to Presbyopia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1metal ion bindingGO:0468729.1CRYAA, HIVEP3

Products for genes affiliated with Presbyopia

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Presbyopia

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet