Aliases & Classifications for Presbyopia

Aliases & Descriptions for Presbyopia:

Name: Presbyopia 12 42 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:11638
ICD10 33 H52.4
ICD9CM 35 367.4
MeSH 42 D011305
SNOMED-CT 64 155135005 41256004
UMLS 69 C0033075

Summaries for Presbyopia

MalaCards based summary : Presbyopia is related to refractive error and cycloplegia, and has symptoms including aniseikonia An important gene associated with Presbyopia is CRYAA (Crystallin Alpha A). The drugs Dipivefrin and Alkylating Agents have been mentioned in the context of this disorder. Affiliated tissues include eye, testes and cortex, and related phenotype is vision/eye.

Wikipedia : 71 Presbyopia is a condition associated with aging of the eye that results in progressively worsening... more...

Related Diseases for Presbyopia

Graphical network of the top 20 diseases related to Presbyopia:



Diseases related to Presbyopia

Symptoms & Phenotypes for Presbyopia

UMLS symptoms related to Presbyopia:


aniseikonia

MGI Mouse Phenotypes related to Presbyopia:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 vision/eye MP:0005391 8.92 BFSP1 BFSP2 MIP RP1L1

Drugs & Therapeutics for Presbyopia

Drugs for Presbyopia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 36)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dipivefrin Approved Phase 4 52365-63-6 3105
2 Alkylating Agents Phase 4
3 Anti-Bacterial Agents Phase 4
4 Antibiotics, Antitubercular Phase 4
5 Mitomycins Phase 4
6 Nucleic Acid Synthesis Inhibitors Phase 4
7 Vitamins Phase 4
8 Omega 3 Fatty Acid Nutraceutical Phase 4
9
Tropicamide Approved Phase 2 1508-75-4 5593
10 Ophthalmic Solutions Phase 1, Phase 2
11 Pharmaceutical Solutions Phase 1, Phase 2
12
Pilocarpine Approved 54-71-7, 92-13-7 5910
13
Miconazole Approved, Investigational, Vet_approved 22916-47-8 4189
14
Salicylic acid Approved, Vet_approved 69-72-7 338
15
Dopamine Approved 51-61-6, 62-31-7 681
16
Menthol Approved 2216-51-5 16666
17
Methamphetamine Approved, Illicit 537-46-2 10836
18 Autonomic Agents
19 Cholinergic Agents
20
Meclocycline 2013-58-3 5480760
21 Neurotransmitter Agents
22 Peripheral Nervous System Agents
23 Anti-Infective Agents
24 Contact Lens Solutions
25 Disinfectants
26
Hydrogen peroxide 7722-84-1 784
27 Anesthetics
28 Antifungal Agents
29 Dermatologic Agents
30 Keratolytic Agents
31 Adrenergic Agents
32 Central Nervous System Stimulants
33 Dopamine Agents
34 Dopamine Uptake Inhibitors
35 Neurotransmitter Uptake Inhibitors
36 Polymethyl Methacrylate

Interventional clinical trials:

(show top 50) (show all 111)
id Name Status NCT ID Phase
1 A Prospective Safety and Effectiveness Study of a New High Repetition Rate Excimer Laser Using LASIK for the Correction of Ammetropia and Presbyopia Unknown status NCT02112968 Phase 4
2 Prospective Investigation of SUPRACOR Visual Outcomes of Presbyopic Hyperopic Patients With and Without Astigmatism Unknown status NCT01628146 Phase 4
3 A Prospective Safety and Effectiveness Study of the 500 Hz Technolas Perfect Vision Excimer Laser in Asian Eyes Using LASIK Unknown status NCT01977807 Phase 4
4 Presbyopia-Correcting Intraocular Lenses (IOLs) Completed NCT00963560 Phase 4
5 A Comparison of Visual Function After Bilateral Implantation of Presbyopia-correcting Intraocular Lenses (IOLs) Completed NCT01166971 Phase 4
6 Clinical Evaluation of Biofinity Multifocal Compared With Air Optix Aqua Multifocal and With PureVision Multifocal Completed NCT01591499 Phase 4
7 Presbyopic Supracor Treatment for Near Myopic/Hyperopic Pseudophakic Eyes Completed NCT01387360 Phase 4
8 Evaluation of the Tecnis™ Multifocal and Crystalens™ Accommodating Intraocular Lenses Completed NCT01061281 Phase 4
9 Comparison of Postoperative Visual Acuity and Spectacle Independence Between the Tecnis Multifocal Intraoculer Lens (IOL) and the Crystalens Accommodating IOL Completed NCT01275118 Phase 4
10 Visual Performance After RESTOR Implantation Completed NCT01065064 Phase 4
11 A Prospective Study to Evaluate the Raindrop Near Vision Inlay in Presbyopic Patients With Treatments to Optimize the Ocular Surface Before Implantation Recruiting NCT03126877 Phase 4
12 A Prospective Study To Evaluate The Raindrop Near Vision Inlay In Presybopic Patients Treated With Mitomycin C Following Femtosecond Flap Creation. Recruiting NCT03101501 Phase 4
13 LaserACE® Procedure Restore Visual Function and Range of Accommodation LaserACE® Procedure Unknown status NCT01491360 Phase 3
14 SUPRACOR for Myopia and Myopic Astigmatism Unknown status NCT01404884 Phase 3
15 Intrastromal Correction of Ametropia by a Femtosecond Laser Unknown status NCT00928122 Phase 3
16 Intrastromal Presbyopia Correction by Means of a Femtosecond Laser Completed NCT01025050 Phase 3
17 Multicenter Evaluation of Safety and Effectiveness of Presbyopic LASIK for Hyperopes Completed NCT00910403 Phase 3
18 A Clinical Trial to Evaluate a Corneal Inlay for the Improvement of Near Vision in Presbyopic Patients Completed NCT01373580 Phase 3
19 Safety and Efficacy Study to Evaluate the Treatment of Both Near and Distance Vision in a Simultaneous Laser Procedure Completed NCT01322919 Phase 3
20 A Clinical Trial to Evaluate a Corneal Inlay for the Improvement of Near and Intermediate Vision in Pseudophakic Presbyopic Subjects Recruiting NCT02668523 Phase 3
21 Clinical Evaluation of the Lenstec SBL-3 Multifocal Intraocular Lens Recruiting NCT02487160 Phase 2, Phase 3
22 Evaluation of the FluidVision Accommodating Lens Active, not recruiting NCT02049567 Phase 2, Phase 3
23 Evaluation of the FluidVisionTM AIOL With an Improved Injector Active, not recruiting NCT02418871 Phase 3
24 Investigation of the Presbia Flexivue Microlens™ Active, not recruiting NCT02110472 Phase 3
25 Randomized Clinical Trial of Bifocal Lenses Versus Computer-specific Progressive Addition Lenses Terminated NCT00585026 Phase 3
26 A Study to Evaluate the Safety and Efficacy of EV06 Ophthalmic Solution in Improving Vision in Subjects With Presbyopia Completed NCT02516306 Phase 1, Phase 2
27 Evaluation of the Efficacy and Safety of PRX-100 in the Treatment of Early to Moderate Presbyopia Completed NCT02554396 Phase 2
28 Safety and Efficacy of AGN-199201 and AGN-190584 in Patients With Presbyopia Completed NCT02197806 Phase 2
29 A Study of the Concurrent Use of AGN-190584 and AGN-199201 in Participants With Presbyopia Recruiting NCT02595528 Phase 2
30 A Safety, Efficacy and Pharmacokinetic Study of AGN-199201 and AGN-190584 in Patients With Presbyopia Recruiting NCT02780115 Phase 2
31 Safety, Tolerability, and Efficacy of PresbiDrops (CSF-1) , a Topical Ophthalmic Drug for Presbyopia Recruiting NCT02745223 Phase 2
32 Safety, Tolerability and Efficacy of PresbiDrops (CSF-1) in Presbyopic Subjects Recruiting NCT02965664 Phase 2
33 A Clinical Trial to Evaluate the Safety and Effectiveness of the Raindrop Near Vision Inlay for Pseudophakic Subjects Terminated NCT03017612 Phase 1
34 Presbyopia Compensation: Looking for Electrophysiological Predictors Unknown status NCT02444130
35 The Effect of Cataract Extraction on the Contractility of Ciliary Muscle Unknown status NCT00624039
36 Functional Assessment of Activities of Daily Living (ADL) in Patients Who Underwent Mini-monovision Correction Unknown status NCT02431156
37 Visual and Economic Profits of ReSTOR® Multifocal Intraocular Lenses (IOL) on Public Health Patients in Spain Unknown status NCT01088282
38 Clinical Evaluation of a Progressive Addition Lens (PAL) Unknown status NCT01443585
39 Development of a Validated Chart for Intermediate Vision Assessment Unknown status NCT02279446
40 Study to Evaluate the Clinical Performance of SynergEyes A2 Hybrid Contact Lenses Unknown status NCT01058629
41 Presbyopia Screening by Community Health Worker in Bangladesh Completed NCT03001258
42 The VEPRO Trial: A Cross-Over Randomised Controlled Trial Comparing 2 Corrective Lenses for Patients With Presbyopia Completed NCT00635115
43 A Comparison of Visual Function After Bilateral Implantation of Presbyopia-Correcting Intraocular Lenses (IOLs) Completed NCT01257217
44 Multifocal Lens Centration and Its Effect on Visual Performance in a Presbyopic Population Completed NCT02228109
45 Trial of the PresView Implant for the Improvement of Near Vision in Patients With Presbyopia Completed NCT01166568
46 A Comparison of Visual Function After Bilateral Implantation of Presbyopia Correcting Intraocular Lenses Completed NCT01299155
47 Performance of a Multifocal Contact Lens - Presbyopia Study Completed NCT02450747
48 Safety and Effectiveness Study of the AcuFocus Corneal Inlay ACI 7000PDT in Presbyopes Completed NCT00850031
49 Safety and Effectiveness of the AcuFocus Corneal Inlay ACI7000PDT in Presbyopes Completed NCT01352442
50 A Continuation Study To Monitor The Long Term Safety Of Patients Completing Protocols ACU-P08-020/020A Completed NCT01895088

Search NIH Clinical Center for Presbyopia

Cochrane evidence based reviews: presbyopia

Genetic Tests for Presbyopia

Anatomical Context for Presbyopia

MalaCards organs/tissues related to Presbyopia:

39
Eye, Testes, Cortex

Publications for Presbyopia

Articles related to Presbyopia:

(show top 50) (show all 425)
id Title Authors Year
1
Correcting presbyopia: the problem of pupil size. ( 28030880 )
2017
2
The Quest for Spectacle Independence: A Comparison of Multifocal Intraocular Lens Implants and Pseudophakic Monovision for Patients with Presbyopia. ( 27792408 )
2017
3
Effect of the Femtosecond Laser on an Intracorneal Inlay for Surgical Compensation of Presbyopia during Cataract Surgery: Scanning Electron Microscope Imaging. ( 27260475 )
2016
4
Protein Disulfide Levels and Lens Elasticity Modulation: Applications for Presbyopia. ( 27233034 )
2016
5
Compensation of Presbyopia With the Light Sword Lens. ( 28002561 )
2016
6
Clinical outcomes of combined versus separate carbachol and brimonidine drops in correcting presbyopia. ( 27981057 )
2016
7
Prevalence of presbyopia in a semi-urban population of southwest, Nigeria: a community-based survey. ( 26874695 )
2016
8
Treatment of Presbyopia in Emmetropes Using a Shape-Changing Corneal Inlay: One-Year Clinical Outcomes. ( 26804761 )
2016
9
Prevalence, Correlates, and Impact of Uncorrected Presbyopia in a Multiethnic Asian Population. ( 27246256 )
2016
10
Functional Visual Acuity of Early Presbyopia. ( 26959362 )
2016
11
Re: Whitman etA al.: Treatment of presbyopia in emmetropes using a shape-changing corneal inlay: one-year clinical outcomes (Ophthalmology 2016;123:466-75). ( 27871403 )
2016
12
Short-term visual performance of soft multifocal contact lenses for presbyopia. ( 27224066 )
2016
13
A decrease in the permeability of aquaporin zero as a possible cause for presbyopia. ( 26615967 )
2016
14
Visual and Refractive Outcomes of a Toric Presbyopia-Correcting Intraocular Lens. ( 26885382 )
2016
15
Contrast Sensitivity in Patients With Emmetropic Presbyopia Before and After Small-Aperture Inlay Implantation. ( 27304602 )
2016
16
AcuFocus Corneal Inlay to Correct Presbyopia Using Femto-LASIK. One Year Results of a Prospective Cohort Study. ( 27116483 )
2016
17
Long-term outcomes of intrastromal femtosecond laser presbyopia correction: 3-year results. ( 26903524 )
2016
18
Causes and correction of dissatisfaction after implantation of presbyopia-correcting intraocular lenses. ( 27784985 )
2016
19
Pharmacological Treatment of Presbyopia by Novel Binocularly Instilled Eye Drops: A Pilot Study. ( 27168149 )
2016
20
Presbyopia: physiology, prevention and pathways to correction. ( 26769325 )
2016
21
Aspheric Micro-monovision LASIK in Correction of Presbyopia and Myopic Astigmatism: Early Clinical Outcomes in a Chinese Population. ( 27722755 )
2016
22
Six-month visual outcomes for the correction of presbyopia using a small-aperture corneal inlay: single-site experience. ( 27843289 )
2016
23
Keratectasia After Presbyopia Treatment With INTRACOR. ( 27755289 )
2016
24
Finding routes towards understanding and the successful correction of presbyopia. ( 27863717 )
2016
25
Population-based study of presbyopia in Nicaragua. ( 27397616 )
2016
26
Presbyopia and near spectacle correction coverage among public school teachers in Ifo Township, South-West Nigeria. ( 27623724 )
2016
27
Multifocal corneal ablation (Supracor) in hyperopic presbyopia: 1-year results in a cross-sectional study. ( 28009399 )
2016
28
Apparent Corneal Ectasia After Bilateral Intrastromal Femtosecond Laser Treatment for Presbyopia. ( 27362883 )
2016
29
Presbyopia compensation: looking for cortical predictors. ( 27107029 )
2016
30
Surgical Correction of Presbyopia: Lenticular, Corneal, and Scleral Approaches. ( 27257729 )
2016
31
Bilateral cataract surgery in a 56-year-old man following presbyopia laser in situ keratomileusis: A case report. ( 28003790 )
2016
32
Surgical correction of presbyopia. ( 27373400 )
2016
33
Evaluating Three Different Methods of Determining Addition in Presbyopia. ( 27621785 )
2016
34
Patient experience of laser in situ keratomileusis and monocular small-aperture corneal inlay implantation for the surgical compensation of presbyopia and additional ametropia. ( 27059801 )
2016
35
Surgical treatment of presbyopia with central presbyopic keratomileusis: One-year results. ( 27839595 )
2016
36
Near vision examination in presbyopia patients: Do we need good homologated near vision charts? ( 27844022 )
2016
37
Hydrogel Inlay for Presbyopia: Objective and Subjective Visual Outcomes. ( 26158925 )
2015
38
Prevalence of presbyopia and spectacle correction coverage in a rural population of North West Nigeria. ( 26170613 )
2015
39
Towards better estimates of uncorrected presbyopia. ( 26600605 )
2015
40
Safety and effectiveness of a new toric presbyopia-correcting posterior chamber silicone intraocular lens. ( 25661122 )
2015
41
Implantable inlay devices for presbyopia: the evidence to date. ( 25609913 )
2015
42
Multifocal Intraocular Lens Results in Correcting Presbyopia in Eyes After Radial Keratotomy. ( 26625851 )
2015
43
One-year results of simultaneous laser in situ keratomileusis and small-aperture corneal inlay implantation for hyperopic presbyopia: comparison by age. ( 25532642 )
2015
44
Computer-animated model of accommodation and presbyopia. ( 25661140 )
2015
45
A review of the surgical options for the correction of presbyopia. ( 25908836 )
2015
46
Correlation between ocular biometry and amplitude of accommodation in early presbyopia. ( 25633619 )
2015
47
The Global Burden of Potential Productivity Loss from Uncorrected Presbyopia. ( 26190438 )
2015
48
Simulated prototype of posterior chamber phakic intraocular lens for presbyopia correction. ( 26703304 )
2015
49
Central PresbyLASIK for Hyperopia and Presbyopia Using Micro-monovision With the Technolas 217P Platform and SUPRACOR Algorithm. ( 26248347 )
2015
50
The role of sensory ocular dominance on through-focus visual performance in monovision presbyopia corrections. ( 26024464 )
2015

Variations for Presbyopia

Expression for Presbyopia

Search GEO for disease gene expression data for Presbyopia.

Pathways for Presbyopia

GO Terms for Presbyopia

Cellular components related to Presbyopia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 intermediate filament GO:0005882 8.96 BFSP1 BFSP2
2 cell cortex GO:0005938 8.62 BFSP1 BFSP2

Biological processes related to Presbyopia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 response to stimulus GO:0050896 9.43 BFSP2 CRYAA MIP
2 cytoskeleton organization GO:0007010 9.32 BFSP1 BFSP2
3 cell maturation GO:0048469 9.16 BFSP1 BFSP2
4 lens fiber cell development GO:0070307 8.96 BFSP1 BFSP2
5 visual perception GO:0007601 8.92 BFSP2 CRYAA MIP RP1L1

Molecular functions related to Presbyopia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 8.96 BFSP1 BFSP2
2 structural constituent of eye lens GO:0005212 8.92 BFSP1 BFSP2 CRYAA MIP

Sources for Presbyopia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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