MCID: PRS025
MIFTS: 30

Presbyopia malady

Eye diseases category

Summaries for Presbyopia

About this section
Sources:
63Wikipedia, 32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:63 Presbyopia is a condition where, with age, the eye exhibits a progressively diminished ability to focus... more...

MalaCards: Presbyopia is related to cataract and refractive error. An important gene associated with Presbyopia is CRYAA (crystallin, alpha A), and among its related pathways is Non-integrin membrane-ECM interactions. Affiliated tissues include eye, cortex and testes.

Aliases & Classifications for Presbyopia

About this section
Sources:
8Disease Ontology, 10DISEASES, 60UMLS, 27ICD9CM, 56SNOMED-CT, 34MeSH, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Eye diseases


Aliases & Descriptions:

presbyopia 8 10 60


External Ids:

Disease Ontology8 DOID:11638
ICD9CM27 367.4
SNOMED-CT56 41256004, 155135005
MeSH34 D011305
ICD1025 H52.4

Related Diseases for Presbyopia

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Presbyopia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 18)
idRelated DiseaseScoreTop Affiliating Genes
1cataract30.6CRYAA
2refractive error10.5
3astigmatism10.4
4myopia10.4
5retinitis10.1
6epidermolysis bullosa10.0LAMA3
7senile cataract10.0LAMA3, CRYAA
8dermatomyositis10.0FBN1
9glaucoma10.0LAMA3, FBN1
10myopia 610.0LAMA3, FBN1
11alternating exotropia9.9
12monofixation syndrome9.9
13amyloidosis9.9
14corneal deposit9.9
15esotropia9.9
16exotropia9.9
17eye disease9.9
18strabismus9.9

Graphical network of diseases related to Presbyopia:



Diseases related to presbyopia

Clinical Features for Presbyopia

About this section

Drugs & Therapeutics for Presbyopia

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Presbyopia

Drug clinical trials:

Search ClinicalTrials for Presbyopia

Search NIH Clinical Center for Presbyopia

Search CenterWatch for Presbyopia

Genetic Tests for Presbyopia

About this section

Anatomical Context for Presbyopia

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Presbyopia:

32
Eye, Cortex, Testes

Animal Models for Presbyopia or affiliated genes

About this section

Publications for Presbyopia

About this section
Sources:
50PubMed
See all sources

Articles related to Presbyopia:

(show top 50)    (show all 350)
idTitleAuthorsYear
1
One-year experience in presbyopia correction with biaspheric multifocal central presbyopia laser in situ keratomileusis. (23086358)
2013
2
Aspheric spectacles for correcting presbyopia with myopia and astigmatism. (23052068)
2012
3
LASIK for presbyopia correction in emmetropic patients using aspheric ablation profiles and a micro-monovision protocol with the Carl Zeiss Meditec MEL 80 and VisuMax. (22869232)
2012
4
Development of a questionnaire to assess the relative subjective benefits of presbyopia correction. (22078121)
2012
5
Objective evaluation of through-focus optical performance of presbyopia-correcting intraocular lenses using an optical bench system. (21700107)
2011
6
LASIK for Myopic Astigmatism and Presbyopia Using Non-Linear Aspheric Micro-Monovision with the Carl Zeiss Meditec MEL 80 Platform. (20205360)
2011
7
Intracorneal inlay to correct presbyopia: Long-term results. (21570249)
2011
8
An international survey of contact lens prescribing for presbyopia. (21039845)
2011
9
Presbyopia and near-vision impairment in rural northern China. (21212182)
2011
10
Predicting clinical visual acuity of presbyopia treatments. (20199016)
2010
11
Presbyopia corrections with the WaveLight ALLEGRETTO: 3-month results. (20954678)
2010
12
Uncorrected refractive errors, presbyopia and spectacle coverage: results from a rapid assessment of refractive error survey. (19874105)
2009
13
Gender differences in presbyopia. (19888367)
2009
14
Contact lens correction of presbyopia. (19535284)
2009
15
Presbyopia-correcting intraocular lenses. (19077824)
2009
16
Presbyopia correcting intraocular lenses: what do I do? (18358849)
2008
17
Functional presbyopia in Kenya. (18983565)
2008
18
Comparison of Acri. Smart multifocal IOL, crystalens AT-45 accommodative IOL, and Technovision presbyLASIK for correcting presbyopia. (18416265)
2008
19
Refractive lens exchange for presbyopia. (18406656)
2008
20
Refractive enhancement following presbyopia-correcting intraocular lens implantation. (18090892)
2008
21
Presbyopia correction: managing the complex patient. (17984496)
2007
22
Uncorrected refractive error and presbyopia: accommodating the unmet need. (17576703)
2007
23
Presbyopia: prevalence, impact, and interventions. (17971909)
2007
24
Traditional methods for the treatment of presbyopia: spectacles, contact lenses, bifocal contact lenses. (16500526)
2006
25
Evidence for delayed presbyopia after photorefractive keratectomy for myopia. (16650666)
2006
26
Presbyopia compensation with a quartic axicon. (16357650)
2005
27
Is binocular contrast sensitivity at distance compromised with multifocal soft contact lenses used to correct presbyopia? (12858086)
2003
28
A longitudinal study of vergence adaptation in incipient presbyopia. (14622353)
2003
29
Presbyopia among normal individuals. (12605263)
2003
30
Gender-related optical aspects of the onset of presbyopia. (12014486)
2002
31
Theory behind surgical correction of presbyopia. (11406427)
2001
32
A study of racial differences in age at onset and progression of presbyopia. (9109295)
1997
33
The aetiology of presbyopia: a summary of the role of lenticular and extralenticular structures. (8524570)
1995
34
Laser correction of hyperopia and presbyopia. (7896526)
1994
35
Tonic vergence, age and clinical presbyopia. (8265176)
1993
36
Presbyopia isn't just for Presbyterians. (1499820)
1992
37
The increasing sclerosis of the human lens with age and its relevance to accommodation and presbyopia. (1869070)
1991
38
Explanation for good visual acuity in uncorrected residual hyperopia and presbyopia after radial keratotomy. (2387693)
1990
39
Forced vergence fixation disparity curves in presbyopia. (3789080)
1986
40
In and out of office communication for more efficient care (presbyopia). (6841880)
1983
41
The geographic factor in the onset of presbyopia. (545835)
1979
42
Proceedings: Some experimental studies of human accommodation and presbyopia. (4759738)
1973
43
Presbyopia corrected with single vision spectacles or corneal lenses in preference to bifocal corneal lenses. (5991948)
1966
44
The omnifocal lens for presbyopia. (13997765)
1962
45
The amplitude of accommodation in presbyopia. (13283035)
1956
46
Accommodative-convergence in presbyopia. (14799593)
1951
47
Management of early presbyopia and bilateral aphakia. (18120332)
1949
48
A case of latent hypermetropia and suppression with incipient presbyopia. (18883934)
1948
49
A GAS MASK WAFER FOR PRESBYOPIA. (18170047)
1944
50
THE RELATION OF EXOPHORIA IN EARLY PRESBYOPIA TO REFRACTIVE ERRORS. (18168355)
1924

Genetic Variations for Presbyopia

About this section

Expression for genes affiliated with Presbyopia

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Presbyopia

Search GEO for disease gene expression data for Presbyopia.

Pathways for genes affiliated with Presbyopia

About this section
Sources:
53Reactome, 29KEGG
See all sources

Pathways related to Presbyopia according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.5LAMA3, FBN1

Compounds for genes affiliated with Presbyopia

About this section

GO Terms for genes affiliated with Presbyopia

About this section
Sources:
16Gene Ontology
See all sources

Cellular components related to Presbyopia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1basement membraneGO:0056049.2LAMA3, FBN1
2extracellular spaceGO:0056158.5LEFTY1, FBN1, UCN2

Biological processes related to Presbyopia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of gene expressionGO:0106299.4CRYAA, UCN2

Products for genes affiliated with Presbyopia

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Presbyopia

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet