MCID: PRM024
MIFTS: 37

Primary Angle-Closure Glaucoma

Categories: Eye diseases

Aliases & Classifications for Primary Angle-Closure Glaucoma

MalaCards integrated aliases for Primary Angle-Closure Glaucoma:

Name: Primary Angle-Closure Glaucoma 12 52 14 69
Primary Angle Closure Glaucoma 12
Angle Closure Glaucoma 69

Classifications:



External Ids:

Disease Ontology 12 DOID:1405
ICD10 33 H40.2 H40.20
ICD9CM 35 365.2 365.20
NCIt 47 C34640
UMLS 69 C0017606

Summaries for Primary Angle-Closure Glaucoma

MalaCards based summary : Primary Angle-Closure Glaucoma, also known as primary angle closure glaucoma, is related to open-angle glaucoma and cataract. An important gene associated with Primary Angle-Closure Glaucoma is MYOC (Myocilin). The drugs Topiramate and Acetazolamide have been mentioned in the context of this disorder. Affiliated tissues include eye, testes and lung, and related phenotypes are no phenotypic analysis and vision/eye

Related Diseases for Primary Angle-Closure Glaucoma

Diseases related to Primary Angle-Closure Glaucoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 42)
id Related Disease Score Top Affiliating Genes
1 open-angle glaucoma 10.6
2 cataract 10.6
3 familial male-limited precocious puberty 10.5 CYP1B1 MYOC
4 mycobacterium gordonae 10.4 CYP1B1 MMP9
5 intracranial berry aneurysm 10.4 CYP1B1 OPTN
6 amelogenesis imperfecta hypomaturation type 10.4 MMP9 MTHFR
7 multiple cranial nerve palsy 10.4 MFRP OPTN
8 ureter cancer 10.4 COL11A1 OPTN
9 conjunctival folliculosis 10.4 CYP1B1 OPTN
10 monofixation syndrome 10.3 COL11A1 OPTN
11 retinitis 10.3
12 epileptic encephalopathy, early infantile, 7 10.3 COL11A1 MMP9
13 disuse amblyopia 10.2 MFRP OPTN
14 optic atrophy plus syndrome 10.2 MYOC OPTN
15 glaucoma 1a, primary open angle 10.1 CYP1B1 MYOC OPTN
16 opisthorchiasis 10.1 CYP1B1 MYOC OPTN
17 allergic contact dermatitis of eyelid 10.1 MFRP MYOC OPTN
18 secondary corneal edema 10.1 CYP1B1 MYOC OPTN
19 neuropathy 10.1
20 taeniasis 10.1 CYP1B1 MYOC OPTN
21 glaucoma 3a, primary open angle, congenital, juvenile, or adult onset 10.1 CYP1B1 MYOC OPTN
22 lactocele 10.1 CYP1B1 MYOC OPTN
23 amyotrophic lateral sclerosis 12 10.1 CYP1B1 MYOC OPTN
24 nail disorder, nonsyndromic congenital, 1 10.1 CYP1B1 MYOC OPTN
25 separation anxiety disorder 10.1 CYP1B1 MYOC OPTN
26 prostate carcinoma in situ 10.1 MFRP MYOC OPTN
27 intra-abdominal lymph node mast cell malignancy 10.1 MMP9 MTHFR
28 endotheliitis 10.0
29 dental abscess 10.0 KERA MTHFR
30 itpa-related altered drug metabolism 10.0 MFRP VSX2
31 type i ehlers-danlos syndrome 10.0 CYP1B1 OPTN
32 choroiditis 9.9
33 entropion 9.9
34 rubeosis iridis 9.9
35 ocular hypertension 9.9
36 refractive error 9.9
37 retinitis pigmentosa 9.9
38 cornea plana 9.9
39 temple syndrome 9.8 MFRP VSX2
40 myopathy of extraocular muscle 9.8 MYOC OPTN
41 megacolon 9.7 MTHFR VSX2
42 acute poststreptococcal glomerulonephritis 6.0 COL11A1 CYP1B1 HTR3C KERA MFRP MMP9

Comorbidity relations with Primary Angle-Closure Glaucoma via Phenotypic Disease Network (PDN):


Hypertension, Essential

Graphical network of the top 20 diseases related to Primary Angle-Closure Glaucoma:



Diseases related to Primary Angle-Closure Glaucoma

Symptoms & Phenotypes for Primary Angle-Closure Glaucoma

MGI Mouse Phenotypes related to Primary Angle-Closure Glaucoma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 no phenotypic analysis MP:0003012 9.43 MTHFR MYOC OPTN PARL TXNRD2 VSX2
2 vision/eye MP:0005391 9.17 CYP1B1 KERA MFRP MMP9 MTHFR MYOC

Drugs & Therapeutics for Primary Angle-Closure Glaucoma

Drugs for Primary Angle-Closure Glaucoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 83)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Topiramate Approved Phase 4 97240-79-4 5284627
2
Acetazolamide Approved, Vet_approved Phase 4 59-66-5 1986
3
Pilocarpine Approved Phase 4 54-71-7, 92-13-7 5910
4
Travoprost Approved Phase 4,Phase 3 157283-68-6 5282226
5
Latanoprost Approved, Investigational Phase 4,Phase 3 130209-82-4 5282380 5311221
6
Brinzolamide Approved Phase 4,Phase 3 138890-62-7 68844
7
Timolol Approved Phase 4,Phase 3 26839-75-8 33624 5478
8
Maleic acid Experimental Phase 4 110-16-7 444266
9 Anticonvulsants Phase 4
10 Anti-Obesity Agents Phase 4
11 Neuroprotective Agents Phase 4,Phase 3,Phase 2
12 Protective Agents Phase 4,Phase 3,Phase 2
13 Carbonic Anhydrase Inhibitors Phase 4
14 diuretics Phase 4
15 Natriuretic Agents Phase 4
16 Antihypertensive Agents Phase 4,Phase 3,Phase 2
17 Autonomic Agents Phase 4,Phase 2,Phase 3
18 Neurotransmitter Agents Phase 4,Phase 3,Phase 2
19 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3
20 Ophthalmic Solutions Phase 4,Phase 3,Phase 2
21 Pharmaceutical Solutions Phase 4,Phase 2,Phase 3
22 Adrenergic Agents Phase 4,Phase 3,Phase 2
23 Adrenergic Agonists Phase 4,Phase 3,Phase 2
24 Adrenergic alpha-2 Receptor Agonists Phase 4,Phase 3
25 Adrenergic alpha-Agonists Phase 4,Phase 3,Phase 2
26 Adrenergic Antagonists Phase 4,Phase 3
27 Adrenergic beta-Antagonists Phase 4,Phase 3
28 Anti-Arrhythmia Agents Phase 4,Phase 3
29 Brimonidine Tartrate Phase 4,Phase 3 70359-46-5
30 Cholinergic Agents Phase 4
31 Brimonidine Tartrate, Timolol Maleate Drug Combination Phase 4
32
Glatiramer Acetate Approved, Investigational Phase 3 147245-92-9 3081884
33
Triamcinolone Approved, Vet_approved Phase 2, Phase 3 124-94-7 31307
34
Epinephrine Approved, Vet_approved Phase 2, Phase 3 51-43-4 5816
35 Racepinephrine Approved Phase 2, Phase 3
36 Tetrahydrozoline Phase 3
37 Adjuvants, Immunologic Phase 3
38 Antirheumatic Agents Phase 3
39 Immunosuppressive Agents Phase 3,Phase 2
40 Anti-Inflammatory Agents Phase 2, Phase 3
41 glucocorticoids Phase 2, Phase 3
42 Hormone Antagonists Phase 2, Phase 3
43 Hormones Phase 2, Phase 3
44 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2, Phase 3
45 Alkylating Agents Phase 3
46 Anti-Bacterial Agents Phase 3
47 Antibiotics, Antitubercular Phase 3
48 Mitomycins Phase 3
49 Nucleic Acid Synthesis Inhibitors Phase 3
50 triamcinolone acetonide Phase 2, Phase 3

Interventional clinical trials:

(show top 50) (show all 51)

id Name Status NCT ID Phase Drugs
1 Relationship Between Topiramate Use and Ocular Angle Status Unknown status NCT00153699 Phase 4 Topiramate
2 Combined Phacotube vs Phacotrabeculectomy:A Randomized Controlled Trial Unknown status NCT00273221 Phase 4
3 ALPI vs Medical Therapy Effects on Optic Nerve Structure & Function Unknown status NCT00485238 Phase 4 Intravenous acetazolamide
4 Travoprost 0.004% Versus Pilocarpine 1% in Patients With Chronic Angle Closure Glaucoma (CACG) Completed NCT00762645 Phase 4 Travoprost 0.004% (Travatan);Pilocarpine 1%
5 Exploratory Study Comparing Signs and Symptoms in Patients With Ocular Hypertension or Glaucoma Using Xalatan R® or Travatan Z® Completed NCT00799682 Phase 4 Xalatan;Travatan Z
6 Azopt (Brinzolamide 1.0%) Plus Travatan (Travoprost 0.004%) in Treating Patients With Chronic Angle-Closure Glaucoma (CACG) Terminated NCT00758342 Phase 4 Travoprost 0.004% + Brinzolamide 1.0%;Travoprost 0.004% + Tears Natural
7 Study of Brimonidine and Timolol Ophthalmic Solution With Latanoprost Compared With Latanoprost in Glaucoma Patients Terminated NCT01151904 Phase 4 brimonidine 0.2%/timolol 0.5% fixed combination ophthalmic solution;latanoprost
8 Argon Laser Peripheral Iridoplasty for Primary Angle Closure Glaucoma Unknown status NCT00980473 Phase 3 Travatan/ Timolol/Azopt
9 Intraocular Pressure (IOP) Lowering Effect of Selective Laser Trabeculoplasty Versus Prostaglandin Analogues in Angle Closure Glaucoma Unknown status NCT01004900 Phase 3 Travoprost/ Timolol/ Azopt/ Brimonidine
10 Investigating the Neuroprotective Effect of Cop-1 (Copaxone) in Acute Primary Angle Closure Unknown status NCT01936129 Phase 3 Copaxone;Placebo (buffered normal saline w/v)
11 A Safety and Efficacy Study of Travoprost 0.004% Compared to Latanoprost 0.005% in Patients With Chronic Angle-Closure Glaucoma Completed NCT00051181 Phase 3 Travoprost (0.004%);Latanoprost (0.005%)
12 Oculusgen (Ologen) Glaucoma MMC Control in Estonia Completed NCT00524758 Phase 3 MMC in Trabeculectomy
13 Will the Use of Triesence During Glaucoma Surgery Provide Lower Eye Pressure and Improve the Results of the Surgery? Completed NCT00853905 Phase 2, Phase 3 Triesence;balanced salt solution BSS
14 Prophylactic Topical Epinephrine to Reduce Bleeding in Transbronchial Lung Biopsies Recruiting NCT03126968 Phase 2, Phase 3 Topical epinephrine;Placebos
15 A Study to Assess the Effect of Rho-Kinase Inhibitor AR-12286 Ophthalmic Solution 0.5% and 0.7% in Patients With Chronic Angle-closure Glaucoma Unknown status NCT02152774 Phase 2 Rho-Kinase Inhibitor
16 Use of Topical Euphrasia, a Homeopathic Remedy in Ophthalmology Unknown status NCT02416128 Phase 2 Euphrasia;Prednisolone acetate
17 Phase IIA Double-Masked Randomized Sham-Controlled Trial of QPI-1007 Delivered by a Single Intravitreal Injection to Subjects With Acute Primary Angle-Closure Glaucoma (APACG) Completed NCT01965106 Phase 2 QPI-1007 Injection;(including placebo)
18 The Genetic Study of Primary Angle-Closure Glaucoma Unknown status NCT00155857
19 Comparison of Bimatoprost and Latanoprost in Patients With Chronic Angle-Closure Glaucoma: A Randomized Cross-Over Study Unknown status NCT00567788 Latanoprost-Bimatoprost;Bimatoporost-Latanoprost
20 Optical Coherence Tomography Quantitative Analysis of Changes in Anterior Chamber After Laser Peripheral Lridotomy Unknown status NCT02279472
21 Prevalence of Angle Closure in Caucasian Hyperopes Unknown status NCT00823706
22 Angle Closure (Glaucoma) in Caucasians Unknown status NCT02054403
23 Protective Effect of Phenytoin on Glaucoma Unknown status NCT00739154
24 Comparison of Phacotrabeculectomy and Trabeculectomy in the Treatment of Primary Angle-closure Glaucoma (PACG) Completed NCT01298635
25 Comparison of Anterior Chamber Paracentesis and Conventional Mannitol Infusion in Patients With Primary Acute Angle-closure Glaucoma Completed NCT01266343
26 Primary Angle Closure Glaucoma and Aqueous Dynamics Completed NCT00719290
27 Laser Iridotomy Versus Phacoemulsification in Acute Angle Closure Completed NCT00350428
28 An Open Label Study Assessing the 24-hour Intraocular Pressure Pattern in PAC and PACG Patients, Before and After Laser Peripheral Iridotomy Completed NCT01906138
29 Comparison of Gonioscopy With Cirrus and Visante Completed NCT01895686
30 Prospective Evaluation of the Efficacy of Pascal Laser Iridotomy and Pascal Laser Peripheral Iridoplasty: A Pilot Study Completed NCT01020071
31 Dysphotopsia Following Laser Peripheral Iridotomy Completed NCT01758237
32 Water Drinking Test in Patients With Occludable Angle Completed NCT02613533
33 Comparison of Superior vs Nasal/Temporal Laser Peripheral Iridotomy in Primary Angle Closure Completed NCT03187821
34 Short-term Outcomes of Iridoplasty for Persistent Angle Closure Despite Patent Iridotomies Completed NCT02199158
35 Immediate Anterior Chamber Paracentesis With A 30-Gauge Needle for Acute Primary Angle - Closure Completed NCT01923454 Acetazolamide
36 Sequential Laser Iridotomy Using Argon and Q-Switched 532 nm Frequency Doubled Neodymium Yag Laser: A Pilot Study Completed NCT00452998
37 Role of Polymorphisms in the IL-1 Gene Cluster Completed NCT00346541
38 Will Listening to Music Make it Easier to Take a Visual Field Test? Completed NCT01027039
39 Comparing Phaco/IOL Versus Phaco/IOL + Goniosynechialysis in Subjects With PACG Completed NCT02376725
40 The Effect of Ocular Massage on the Management of Elevated Intraocular Pressure After Acute Angle Closure Completed NCT02539758
41 Prevalence of Corneal Astigmatism Before Glaucoma Surgery in Chinese Patients With Primary Angle-closure Glaucoma Recruiting NCT03159780
42 Comparing Nd:YAG Laser and Sequential Double Frequency YAG-Nd:YAG Laser Iridotomy Recruiting NCT02474238
43 Anterior Segment Imaging With Ultrahigh-resolution OCT in Patients With Glaucoma and PEX - a Pilot Study Recruiting NCT02865473 Pilocarpine
44 Laser Peripheral Iridotomy Plus Laser Peripheral Iridoplasty for Primary Angle Closure Recruiting NCT02613013 Pilocarpine;Proparacaine
45 Treatment Outcomes of MicroPulse Trans-scleral Cyclophotocoagulation in Uncontrolled Glaucoma Recruiting NCT03187418
46 Clinical Study of LPI on Different Sites of Iris Active, not recruiting NCT02870504
47 Clinical Study of LPI With Different Laser Wavelengths Active, not recruiting NCT02901730
48 Advanced Glaucoma Progression Study Active, not recruiting NCT01742819
49 Clinical Efficacy and Safety of Minimally Invasive Glaucoma Surgery on Primary Angle Closure Glaucoma Not yet recruiting NCT02964676
50 Patch Graft Material Safety and Effectiveness in Covering Glaucoma Drainage Device Tube Terminated NCT01301378

Search NIH Clinical Center for Primary Angle-Closure Glaucoma

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Genetic Tests for Primary Angle-Closure Glaucoma

Anatomical Context for Primary Angle-Closure Glaucoma

MalaCards organs/tissues related to Primary Angle-Closure Glaucoma:

39
Eye, Testes, Lung, Retina, Endothelial, Brain

Publications for Primary Angle-Closure Glaucoma

Articles related to Primary Angle-Closure Glaucoma:

(show top 50) (show all 382)
id Title Authors Year
1
Early lens extraction with intraocular lens implantation for the treatment of primary angle closure glaucoma: an economic evaluation based on data from the EAGLE trial. ( 28087548 )
2017
2
Long-chain unsaturated fatty acids as possible important metabolites for primary angle-closure glaucoma based on targeted metabolomic analysis. ( 28214354 )
2017
3
Increased aquaporin-1 levels in lens epithelial cells with primary angle-closure glaucoma. ( 28730113 )
2017
4
Association of Plasma Complement C3 Levels With Primary Angle-Closure Glaucoma in Older Women. ( 28134964 )
2017
5
Multiplex Cytokine Analysis of Aqueous Humor from the Patients with Chronic Primary Angle Closure Glaucoma. ( 28937875 )
2017
6
Evaluation of potential risk factors for development of primary angle-closure glaucoma in Bouviers des Flandres. ( 28001106 )
2017
7
Long-Term Evaluation of Specular Microscopic Changes Following Nd: YAG Iridotomy in Chronic Primary Angle-Closure Glaucoma Eyes. ( 28731934 )
2017
8
Re: Narayanaswamy etA al.: Argon laser peripheral iridoplasty for primary angle-closure glaucoma: a randomized controlled trial (Ophthalmology. 2016;123:514-521). ( 28335943 )
2017
9
A new approach for the management of primary angle-closure glaucoma after EAGLE trial. ( 28522116 )
2017
10
Common polymorphisms of the hOGG1, APE1 and XRCC1 genes correlate with the susceptibility and clinicopathological features of primary angle-closure glaucoma. ( 28396513 )
2017
11
Comparison of self-measured diurnal intraocular pressure profiles using rebound tonometry between primary angle closure glaucoma and primary open angle glaucoma patients. ( 28333942 )
2017
12
Long-Term Outcomes of Primary Trabeculectomy in Diabetic Patients without Retinopathy with Primary Angle-Closure Glaucoma. ( 28337343 )
2017
13
Visual Field Progression in Patients with Primary Angle-Closure Glaucoma Using Pointwise Linear Regression Analysis. ( 28372858 )
2017
14
Treatment of primary angle-closure glaucoma: Does early lens extraction help? ( 28816215 )
2017
15
Success rates of 2-site phacoemulsification combined with fornix-based trabeculectomy using mitomycin C for primary angle-closure glaucoma and primary open-angle glaucoma in an Asian population. ( 28188405 )
2017
16
Cost-effectiveness of Phacoemulsification versus Combined Phacotrabeculectomy for Treating Primary Angle Closure Glaucoma. ( 28858162 )
2017
17
Optical Coherence Tomography Angiography of the Peripapillary Retina in Primary Angle-Closure Glaucoma. ( 28797550 )
2017
18
Decision-making Impairments in Primary Angle-closure Glaucoma Patients. ( 28584204 )
2017
19
Phacoemulsification versus laser iridotomy in primary angle closure glaucoma. A difficult decision. ( 28610807 )
2017
20
Trabecular Meshwork Height in Primary Open-Angle Glaucoma Versus Primary Angle-Closure Glaucoma. ( 28887118 )
2017
21
Vessel Density and Structural Measurements of Optical Coherence Tomography in Primary Angle Closure and Primary Angle Closure Glaucoma. ( 28254626 )
2017
22
Genetic Association of the PARL-ABCC5-HTR3D-HTR3C Locus With Primary Angle-Closure Glaucoma in Chinese. ( 28813580 )
2017
23
Anterior segment imaging-based subdivision of subjects with primary angle-closure glaucoma. ( 27935603 )
2016
24
[Association of PLEKHA7, COL11A1 and PCMTD1-ST18 gene polymorphisms with primary angle closure glaucoma in ethnic Han Chinese from Sichuan]. ( 27455018 )
2016
25
Primary angle closure glaucoma: What we know and what we don't know. ( 28039061 )
2016
26
Impact of Socioeconomic Status on the Diagnosis of Primary Open-Angle Glaucoma and Primary Angle Closure Glaucoma: A Nationwide Population-Based Study in Taiwan. ( 26905307 )
2016
27
Selective Laser Trabeculoplasty in Primary Angle-closure Glaucoma After Laser Peripheral Iridotomy: A Case-Control Study. ( 26945310 )
2016
28
Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma. ( 27064256 )
2016
29
Pattern of Visual Field Loss in Primary Angle-Closure Glaucoma Across Different Severity Levels. ( 27423311 )
2016
30
The association between serum uric acid and glaucoma severity in primary angle closure glaucoma: a retrospective case-control study. ( 27926530 )
2016
31
Factors affecting refractive outcome after cataract surgery in primary angle-closure glaucoma. ( 27082207 )
2016
32
Erratum. Lack of Association Between Corneal Hysteresis and Corneal Resistance Factor With Glaucoma Severity in Primary Angle Closure Glaucoma. ( 26943150 )
2016
33
Patient-Reported Vision-Related Quality-of-Life Differences between Primary Angle-Closure Glaucoma and Primary Open-Angle Glaucoma. ( 27690232 )
2016
34
Limbus-insertion distance of superior rectus in primary angle closure glaucoma: an anterior segment OCT study. ( 27938955 )
2016
35
Effectiveness of early lens extraction for the treatment of primary angle-closure glaucoma (EAGLE): a randomised controlled trial. ( 27707497 )
2016
36
Management of Primary Angle-Closure Glaucoma. ( 26886121 )
2016
37
Intra-ocular pressure fluctuation after cataract surgery in primary angle-closure glaucoma eyes medically controlled after laser iridotomy. ( 27040022 )
2016
38
Factors affecting refractive outcome after cataract surgery in primary angle-closure glaucoma: methodological issues of prediction model - response. ( 27526301 )
2016
39
Argon Laser Peripheral Iridoplasty for Primary Angle-Closure Glaucoma: A Randomized Controlled Trial. ( 26707418 )
2016
40
Trabeculectomy and Combined Phacoemulsification-Trabeculectomy: Outcomes and Risk Factors for Failure in Primary Angle Closure Glaucoma. ( 27513900 )
2016
41
Evaluation of Ex-PRESS implantation combined with phacoemulsification in primary angle-closure glaucoma. ( 27603352 )
2016
42
Phacoemulsification versus combined phacotrabeculectomy in the treatment of primary angle-closure glaucoma with cataract: a Meta-analysis. ( 27162736 )
2016
43
Verification of a formula developed to predict the postoperative intraocular pressure after cataract surgery in primary angle-closure glaucoma. ( 27686500 )
2016
44
Re: Narayanaswamy etA al.: Argon laser peripheral iridoplasty for primary angle-closure glaucoma: a randomized controlled trial (Ophthalmology 2016;123:514-21). ( 27450829 )
2016
45
Primary angle-closure glaucoma: A retrospective interventional case series in South India. ( 27013823 )
2016
46
Factors affecting refractive outcome after cataract surgery in primary angle-closure glaucoma: methodological issues of prediction model. ( 27526198 )
2016
47
Trends in Acute Primary Angle-Closure Glaucoma, Peripheral Iridotomy and Cataract Surgery in Scotland, 1998-2012. ( 26751514 )
2016
48
Managing Primary Angle Closure Glaucoma - The Role of Lens Extraction in this Era. ( 27014390 )
2016
49
Association of Matrix Metalloproteinase-9 (MMP9) Variants with Primary Angle Closure and Primary Angle Closure Glaucoma. ( 27272641 )
2016
50
Lack of Association Between Corneal Hysteresis and Corneal Resistance Factor With Glaucoma Severity in Primary Angle Closure Glaucoma. ( 26517405 )
2015

Variations for Primary Angle-Closure Glaucoma

Expression for Primary Angle-Closure Glaucoma

Search GEO for disease gene expression data for Primary Angle-Closure Glaucoma.

Pathways for Primary Angle-Closure Glaucoma

GO Terms for Primary Angle-Closure Glaucoma

Cellular components related to Primary Angle-Closure Glaucoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 proteinaceous extracellular matrix GO:0005578 8.92 COL11A1 KERA MMP9 MYOC

Biological processes related to Primary Angle-Closure Glaucoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 collagen fibril organization GO:0030199 9.26 COL11A1 CYP1B1
2 endodermal cell differentiation GO:0035987 9.16 COL11A1 MMP9
3 visual perception GO:0007601 9.02 COL11A1 CYP1B1 KERA MFRP VSX2
4 regulation of reactive oxygen species metabolic process GO:2000377 8.96 CYP1B1 PARL

Sources for Primary Angle-Closure Glaucoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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