MCID: PRM032
MIFTS: 27

Primary Congenital Glaucoma malady

Categories: Genetic diseases, Rare diseases, Eye diseases, Fetal diseases

Aliases & Classifications for Primary Congenital Glaucoma

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Aliases & Descriptions for Primary Congenital Glaucoma:

Name: Primary Congenital Glaucoma 22 23 66

Classifications:



Summaries for Primary Congenital Glaucoma

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MalaCards based summary: Primary Congenital Glaucoma is related to glaucoma 3a, primary open angle, congenital, juvenile, or adult onset and peters anomaly. An important gene associated with Primary Congenital Glaucoma is LTBP2 (Latent Transforming Growth Factor Beta Binding Protein 2). Affiliated tissues include eye, testes and brain, and related mouse phenotype vision/eye.

GeneReviews summary for NBK1135

Related Diseases for Primary Congenital Glaucoma

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Diseases in the Juvenile Glaucoma family:

Glaucoma 3, Primary Infantile, B Glaucoma 3, Primary Congenital, D
Glaucoma 3, Primary Congenital, C primary congenital glaucoma
Glaucoma Type 1c Glaucoma, Hereditary
Glaucoma, Hereditary Adult Type 1a Glaucoma, Hereditary Juvenile Type 1b
Glaucoma, Primary Infantile Type 3a Cyp1b1-Related Primary Congenital Glaucoma
Ltbp2-Related Primary Congenital Glaucoma Early-Onset Glaucoma

Diseases related to Primary Congenital Glaucoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 35)
idRelated DiseaseScoreTop Affiliating Genes
1glaucoma 3a, primary open angle, congenital, juvenile, or adult onset31.3CYP1B1, FOXC1, LTBP2, MYOC
2peters anomaly29.2CYP1B1, FOXC1, MYOC
3cyp1b1-related primary congenital glaucoma12.1
4ltbp2-related primary congenital glaucoma12.0
5glaucoma 3, primary congenital, d11.3
6glaucoma 3, primary infantile, b11.2
7glaucoma 1a, primary open angle10.3CYP1B1, MYOC
8familial hyperaldosteronism10.1CYP1B1, MYOC
9open-angle glaucoma10.1
10buphthalmos10.1
11clonorchiasis10.0FOXC1, LTBP2
12hypogonadotropic hypogonadism 24 without anosmia10.0CYP1B1, FOXC1
13retinitis9.9
14paranasal sinus lymphoma9.9MYOC, WDR36
15larsen-like syndrome9.9CYP1B1, FOXC1
16cataract9.9
17secondary corneal edema9.9CYP1B1, LTBP2, MYOC
18iritis9.8CYP1B1, MYOC
19chronic tympanitis9.8CYP1B1, FOXC1, LTBP2
20amyotrophic lateral sclerosis 129.7CYP1B1, MYOC, WDR36
21megalocornea9.7
22lens subluxation9.7
23patau syndrome9.7
24myopia9.7
25peripheral retinal degeneration9.7
26anisometropia9.7
27down syndrome9.7
28corneal dystrophy9.7
29retinal detachment9.7
30retinal degeneration9.7
31neurofibromatosis9.7
32separation anxiety disorder9.7CYP1B1, MYOC, WDR36
33acute contagious conjunctivitis9.4CYP1B1, FOXC1, LTBP2, MYOC
34lactocele9.3CYP1B1, FOXC1, MYOC, WDR36
35primary trimethylaminuria7.5CYP1B1, FOXC1, GLC3B, GLC3C, LTBP2, MYOC

Graphical network of the top 20 diseases related to Primary Congenital Glaucoma:



Diseases related to primary congenital glaucoma

Symptoms for Primary Congenital Glaucoma

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Drugs & Therapeutics for Primary Congenital Glaucoma

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Drugs for Primary Congenital Glaucoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
BevacizumabPhase 41938216974-75-3
Synonyms:
216974-75-3
Avastin
Avastin (TN)
Bevacizumab
Bevacizumab (genetical recombination)
 
Bevacizumab (genetical recombination) (JAN)
D06409
R-435
anti-VEGF monoclonal antibody
antiVEGF
bevacizumab
2
TimololPhase 225126839-75-833624, 5478
Synonyms:
(-)-3-Morpholino-4-(3-tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole
(2S)-1-((1,1-dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-2-propanol
(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
(2S)-1-[(1,1-dimethylethyl)amino]-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
(S)-1-(1,1-(Dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-2-propanol
(S)-1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol
(S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
(S)-timolol
131628-37-0
194288-09-0
26839-75-8
26921-17-5 (maleate (1:1) salt)
AB00513729
AC1L1PYN
AC1Q59QM
Apo-Timol
Apo-Timop
Aquanil
BIDD:GT0073
BPBio1_001008
BRD-K08806317-050-03-6
BSPBio_000916
Betim
Betimol
Betimol (TN)
Blocadren
C07141
C13H24N4O3S
CAS-26921-17-5
CHEBI:9599
CHEMBL499
CID33624
CPD001456519
D08600
DB00373
DB08625
EINECS 248-032-6
HMS2089I11
HSDB 6533
Istalol
L-714,465
LS-122231
Lopac-T-6394
Lopac0_001189
MK-950
NCGC00016038-01
 
NCGC00016038-02
NCGC00016798-01
NCGC00016798-07
NCGC00022033-02
NCGC00022033-04
NCGC00022033-05
Novo-Timol
Nu-Timolol
Oprea1_640981
Optimol
Phoxal-timolol
Prestwick0_000948
Prestwick1_000948
Prestwick2_000948
Prestwick3_000948
Proflax
S(-)-Timolol maleate
S-(-)-3-(3-tert-Butylamino-2-hydroxypropoxy)-4-morpholino-1,2,5-thiadiazole
SAM002564238
SPBio_003075
ST072193
TIM
Temserin
Tenopt
Tim-AK
Timacar
Timacor
Timolol
Timolol (INN)
Timolol (TN)
Timolol GFS
Timolol Maleate, (1:1) Salt
Timolol [USAN]
Timolol anhydrous
Timolol maleate
Timololo
Timololum
Timololum [INN-Latin]
Timopic
Timoptic
Timoptic OcuDose
Timoptic in Ocudose
Timoptic-XE
Timoptol
Tocris-0649
UNII-817W3C6175
timolol
3
Menthol21842216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Caswell No. 540
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
DivK1c_000820
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
FEMA No. 2665
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
HMS1922G13
HMS2092L14
HMS502I22
 
HSDB 5662
HSDB 593
Headache crystals
Hexahydrothymol
I06-1216
I14-7371
IDI1_000820
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Menthomenthol
Menthyl alcohol
MolPort-000-849-729
MolPort-001-793-392
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Neoisomenthol
Peppermint camphor
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
ZINC01482164
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol
4
protease inhibitors5157
Synonyms:
 
protease inhibitors
5Dexamethasone acetate20011177-87-3
6
Dexamethasone200150-02-25743
Synonyms:
(3H)-Dexamethasone
.delta.(sup 1)-9-.alpha.-Fluoro-16-.alpha.-methylcortisol
.gamma.corten
1-Dehydro-16.alpha.-methyl-9.alpha.-fluorohydrocortisone
1-Dehydro-16alpha -methyl-9alpha -fluorohydrocortisone
1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone
1-Dehydro-16α-methyl-9α-fluorohydrocortisone
137098-19-2
16-alpha-Methyl-9-alpha-fluoro-1-dehydrocortisol
16-alpha-Methyl-9-alpha-fluoro-delta(sup 1)-hydrocortisone
16-alpha-Methyl-9-alpha-fluoro-delta1-hydrocortisone
16-alpha-Methyl-9-alpha-fluoroprednisolone
16.alpha.-Methyl-9.alpha.-fluoro-1-dehydrocortisol
16.alpha.-Methyl-9.alpha.-fluoroprednisolone
16alpha -Methyl-9alpha -fluoro-1-dehydrocortisol
16alpha -Methyl-9alpha -fluoroprednisolone
16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol
16alpha-Methyl-9alpha-fluoro-delta(sup 1)-hydrocortisone
16alpha-Methyl-9alpha-fluoroprednisolone
16α-Methyl-9α-fluoro-1-dehydrocortisol
23495-06-9
31375_FLUKA
46165_FLUKA
46165_RIEDEL
50-02-2
8054-59-9
9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11alpha -methylpregna-1,4-diene-3,20-dione
9-Fluoro-16-methylprednisolone
9-alpha-Fluoro-16-alpha-methylprednisolone
9.alpha.-Fluoro-16.alpha.-methylprednisolone
906422-84-2
9A-FLUORO-16BETA-METHYLPREDNISOLONE
9alpha -Fluoro-16alpha -methylprednisolone
9alpha-Fluoro-16alpha-methylprednisolone
9alpha-fluoro-16alpha-methyl-Prednisolone
9α-Fluoro-16α-methylprednisolone
AC-11056
AC1L1L1H
AC1Q29DM
AI3-50934
Adexone
Aeroseb-D
Aeroseb-Dex
Aeroseb-dex
Ak Dex Oph Otic Soln 0.1%
Alcon Brand of Dexamethasone
Anaflogistico
Aphtasolon
Aphthasolone
Apo-dexamethasone
Auxiron
Azimycin (veterinary)
Azium
Azium (Veterinary)
Azium (veterinary)
BIDD:ER0494
BIDD:PXR0060
BRD-K38775274-001-02-3
BRD-K38775274-001-06-4
BSPBio_000995
Bisu DS
Bisu Ds
C15643
C22H29FO5
CCRIS 7067
CHEBI:41879
CHEMBL384467
CID5743
CPD-10549
CPD001227192
Calonat
Corson
Corsone
Cortisumman
D00292
D003907
D1756_SIGMA
D4902_SIGMA
D6645_SIGMA
D8893_SIGMA
D9184_SIGMA
DB01234
DEX
DEXA
DEXONE 0.5
DEXONE 0.75
DEXONE 1.5
DEXONE 4
DXM
DXMS
Decacort
Decacortin
Decaderm
Decadron
Decadron (TN)
Decadron Tablets, Elixir
Decadron, Dexamethasone
Decadron-LA
Decadron-La
Decagel
Decaject
Decaject L.A.
Decaject-L.A.
Decalix
Decameth
Decasone
Decaspray
Dectancyl
Dekacort
Delta1-9alpha-Fluoro-16alpha-methylcortisol
Deltafluorene
Dergramin
Deronil
Desadrene
Desametasone
Desametasone [DCIT]
Desametasone [Dcit]
Desamethasone
Desameton
Deseronil
Dex-Ide
Dex-ide
Dexa
Dexa Mamallet
Dexa mamallet
Dexa-Cortidelt
Dexa-Cortisyl
Dexa-Mamallet
Dexa-Scheroson
Dexa-Sine
Dexa-cortidelt
Dexa-cortisyl
Dexa-scheroson
Dexa-sine
Dexacen-4
Dexacidin
Dexacort
Dexacortal
Dexacortin
Dexadeltone
Dexafarma
Dexair
Dexalona
Dexaltin
Dexametasona
Dexametasona [INN-Spanish]
Dexametasone
 
Dexameth
Dexamethansone
Dexamethasone
Dexamethasone (JP15/USP/INN)
Dexamethasone Acetate
Dexamethasone Alcohol
Dexamethasone Base
Dexamethasone Intensol
Dexamethasone Sodium Phosphate
Dexamethasone [INN:BAN:JAN]
Dexamethasone alcohol
Dexamethasone base
Dexamethasone intensol
Dexamethasone-omega
Dexamethasonum
Dexamethasonum [INN-Latin]
Dexamethazone
Dexamonozon
Dexapolcort
Dexapos
Dexaprol
Dexason
Dexasone
Dexasone 0.5mg
Dexasone 0.75mg
Dexasone 4mg
Dexasporin
Dexinolon
Dexinoral
Dexone
Dexone 0.5
Dexone 0.75
Dexone 1.5
Dexone 4
Dexonium
Dexpak
Dextelan
Dezone
Dinormon
Dxms
ECR Brand of Dexamethasone
EINECS 200-003-9
FT-0080377
Fluormethylprednisolone
Fluormone
Fluorocort
Fortecortin
Foy Brand of Dexamethasone
Gammacorten
HL-dex
HMS1792A17
HMS1990A17
HMS2089N13
HSDB 3053
Hexadecadrol
Hexadrol
Hexadrol Elixir
Hexadrol Tablets
Hexadrol elixir
Hl-Dex
Hl-dex
I06-1196
ICN Brand of Dexamethasone
IontoDex
Isopto-Dex
Isopto-dex
LS-7300
Lokalison F
Lokalison f
Loverine
Luxazone
MK 125
MLS001055412
MLS001332507
MLS001332508
Maxidex
Maxidex Ont 0.1%
Maxidex Sus 0.1%
Maxitrol
Mediamethasone
Merck Brand of Dexamethasone
Merz Brand 1 of Dexamethasone
Merz Brand 2 of Dexamethasone
Methylfluorprednisolone
Mexidex
Millicorten
MolMap_000018
MolPort-003-846-433
Mymethasone
NCGC00091019-01
NCGC00091019-02
NCGC00091019-03
NCGC00091019-04
NCGC00091019-05
NCI60_003067
NSC 34521
NSC34521
Naquasone (veterinary)
Neomycin and polymyxin b sulfates and dexamethasone
Neomycin and polymyxin b sulphates and dexamethasone
OTO-104
Ocu-Trol
Ocu-trol
Oradexon
PHL-dexamethasone
PMS-dexamethasone
Pet Derm III
Pet Derm Iii
Pet derm III
Pet-Derm Iii
Pms Dexamethasone Elixir 0.5mg/5ml
Policort
Posurdex
Prednisolon F
Prednisolon f
Prednisolone F
Prednisolone f
Prodex
S1322_Selleck
SAM002548948
SGCUT00126
SK-Dexamethasone
SK-dexamethasone
SMP1_000092
SMR000857119
SMR001227192
ST50307091
Sandoz dexamethasone
Sk-Dexamethasone
Spectrum5_002019
Spoloven
Sunia Sol D
Sunia sol D
Superprednol
TL8003317
Tobradex
Tobramycin and dexamethasone
Tresaderm (veterinary)
Turbinaire
UNII-7S5I7G3JQL
Visumetazone
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ G1
ZINC03875332
alpha -Fluoro-16-alpha -methylcortisol
delta(Sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta(sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta1-9alpha-Fluoro-16alpha-methylcortisol
dexamethasone
nchembio809-comp2
to_000038
7glucocorticoids4756

Interventional clinical trials:

(show all 17)
idNameStatusNCT IDPhase
1Aphakia Versus Pseudophakia in Children Under 2 Years Undergoing Bilateral Congenital Cataract SurgeryCompletedNCT01297153Phase 4
2Use of Bevacizumab in Trabeculectomy SurgeryCompletedNCT01166594Phase 4
3Comparison of the Ahmed Glaucoma Valve FP7 and FP8 in Pediatric GlaucomaRecruitingNCT01494974Phase 4
4Efficacy of a Timolol Nasal Spray as a Treatment for Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT) - Randomized Trial Versus PlaceboRecruitingNCT02484716Phase 2
5Combined Trab+Trab Versus Combined Trab+Trab With Subconjunctival Implantation of Ologen for Primary Congenital GlaucomaActive, not recruitingNCT02121171Phase 1
6Comparison Between Deep Sclerectomy and Traditional Trabeculotomy & Trabeculectomy in Congenital GlaucomaNot yet recruitingNCT01460017Phase 1
7Endoscopic Goniotomy for Infantile GlaucomaCompletedNCT00338533
8Quality of Life in Children Glaucoma and CataractCompletedNCT02490267
9Mechanism of Aphakic and Pseudophakic Glaucoma in Pediatric PatientsCompletedNCT01136473
10Effect of the Timing of Cataract Surgery on Complications in Patients With Bilateral Congenital CataractsCompletedNCT02581046
11Incidence of Ocular Antibodies in Patients With Sturge - Weber Syndrome (SWS)CompletedNCT00610402
12The Genetic Characteristics in South Korean Patients With Primary Congenital GlaucomaRecruitingNCT01020721
13Genetic Testing in Primary Congenital Glaucoma PatientsRecruitingNCT01136460
14Aqueous Humor Dynamics and Biometric Parameters in Eyes of ChildrenRecruitingNCT01290588
15OCT-guided LALAK in ChildrenRecruitingNCT01579643
16Study of an Intervention to Improve Problem List Accuracy and UseActive, not recruitingNCT01105923
17Repository for Inherited Eye DiseasesSuspendedNCT00378742

Search NIH Clinical Center for Primary Congenital Glaucoma

Genetic Tests for Primary Congenital Glaucoma

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Genetic tests related to Primary Congenital Glaucoma:

id Genetic test Affiliating Genes
1 Primary Congenital Glaucoma23 LTBP2

Anatomical Context for Primary Congenital Glaucoma

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MalaCards organs/tissues related to Primary Congenital Glaucoma:

34
Eye, Testes, Brain

Animal Models for Primary Congenital Glaucoma or affiliated genes

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MGI Mouse Phenotypes related to Primary Congenital Glaucoma:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053918.7CYP1B1, FOXC1, LTBP2, MYOC

Publications for Primary Congenital Glaucoma

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Articles related to Primary Congenital Glaucoma:

(show top 50)    (show all 233)
idTitleAuthorsYear
1
Screening of the LTBP2 gene in 214 Chinese sporadic CYP1B1-negative patients with primary congenital glaucoma. (27293371)
2016
2
Surgical Outcomes of Trabeculotomy in Newborns with Primary Congenital Glaucoma. (27625089)
2016
3
CYP1B1 mutational screening in a Portuguese cohort of primary congenital glaucoma patients. (27268095)
2016
4
Construction of CYP1B1 gene haplotypes predisposing to primary congenital glaucoma through allele-specific PCR/restriction fragment length polymorphism analysis]. (26663047)
2015
5
Surgical interventions for primary congenital glaucoma. (25636153)
2015
6
Genotype-Phenotype Correlations in CYP1B1-Associated Primary Congenital Glaucoma Patients Representing Two Large Cohorts from India and Brazil. (25978063)
2015
7
Mitochondrial transfer RNA variants and primary congenital glaucoma. (25835039)
2015
8
Combined trabeculotomy-trabeculectomy with antimetabolite and releasable suture: outcome with primary congenital glaucoma in a north Indian population. (26695601)
2015
9
CYP1B1 copy number variation is not a major contributor to primary congenital glaucoma. (25750510)
2015
10
The Genetics and the Genomics of Primary Congenital Glaucoma. (26451367)
2015
11
Intraocular pressure measurement by three different tonometers in primary congenital glaucoma. (26005552)
2015
12
Surgical results of trabeculectomy and ahmed valve implantation following a previous failed trabeculectomy in primary congenital glaucoma patients. (25829827)
2015
13
Mutational spectrum of the CYP1B1 gene in Pakistani patients with primary congenital glaucoma: novel variants and genotype-phenotype correlations. (25018621)
2014
14
Long-term efficacy of latanoprost in primary congenital glaucoma. (24158022)
2014
15
Molecular Karyotyping of a Dysmorphic Girl from Saudi Arabia with CYP1B1-negative Primary Congenital Glaucoma. (24911043)
2014
16
Corneal sensitivity and morphology of the corneal subbasal nerve plexus in primary congenital glaucoma. (24480838)
2014
17
Contribution of GLC3A locus to Primary Congenital Glaucoma in Pakistani population. (25674135)
2014
18
Ultrasound biomicroscopy as a diagnostic tool in infants with primary congenital glaucoma. (25228789)
2014
19
Correlations between different tonometries and ocular biometric parameters in patients with primary congenital glaucoma. (24510082)
2013
20
CYP1B1, MYOC, and LTBP2 mutations in primary congenital glaucoma patients in the United States. (23218701)
2013
21
Retinal intrinsic optical signals in a cat model of primary congenital glaucoma. (22395886)
2012
22
Confirmation and further mapping of the GLC3C locus in primary congenital glaucoma. (21622161)
2011
23
Screening of CYP1B1 and LTBP2 genes in Saudi families with primary congenital glaucoma: genotype-phenotype correlation. (22128238)
2011
24
Effects of unilateral topical administration of 0.5% tropicamide on anterior segment morphology and intraocular pressure in normal cats and cats with primary congenital glaucoma. (21923827)
2011
25
Genotype/phenotype correlation in primary congenital glaucoma patients from different ethnic groups of the Israeli population. (21168818)
2011
26
A polymorphism in the CYP1B1 promoter is functionally associated with primary congenital glaucoma. (20660114)
2010
27
Variable expressivity and high penetrance of CYP1B1 mutations associated with primary congenital glaucoma. (19744731)
2009
28
Investigation of CYP1B1 mutations in Chinese patients with primary congenital glaucoma. (19247456)
2009
29
Chronic newborn primary congenital glaucoma with secondary lens subluxation. (19645394)
2009
30
A novel mutation of CYP1B1 gene in primary congenital glaucoma]. (20137445)
2009
31
Exploring the basis of sex bias in primary congenital glaucoma. (23198050)
2009
32
Characterization of the biochemical and structural phenotypes of four CYP1B1 mutations observed in individuals with primary congenital glaucoma. (18622259)
2008
33
Contribution of CYP1B1 mutations and founder effect to primary congenital glaucoma in Mexico. (18414103)
2008
34
Ultrasound biomicroscopic characteristics of the anterior segment in primary congenital glaucoma. (17720567)
2007
35
CYP1B1 mutation profile of Iranian primary congenital glaucoma patients and associated haplotypes. (17591938)
2007
36
A case of primary congenital glaucoma: a diagnostic dilemma. (17400138)
2007
37
Combined trabeculotomy-trabeculectomy as a first surgical procedure for primary congenital glaucoma. (17200580)
2006
38
Gene symbol: CYP1B1. Disease: Primary congenital glaucoma. Accession #Hd0515. (17297684)
2006
39
Correlations of genotype with phenotype in Indian patients with primary congenital glaucoma. (15037581)
2004
40
Results of the Susanna implant in patients with refractory primary congenital glaucoma. (15616507)
2004
41
Identification of R368H as a predominant CYP1B1 allele causing primary congenital glaucoma in Indian patients. (14507861)
2003
42
Molecular genetics of primary congenital glaucoma in Brazil. (12036985)
2002
43
Primary congenital glaucoma: three case reports on novel mutations and combinations of mutations in the GLC3A (CYP1B1) gene. (11558822)
2001
44
Primary congenital glaucoma and erupted teeth (natal teeth) in the newborn: a report of two cases. (11563786)
2001
45
Molecular genetics of primary congenital glaucoma. (11026969)
2000
46
Mutations in CYP1B1, the gene for cytochrome P4501B1, are the predominant cause of primary congenital glaucoma in Saudi Arabia. (9463332)
1998
47
Sequence analysis and homology modeling suggest that primary congenital glaucoma on 2p21 results from mutations disrupting either the hinge region or the conserved core structures of cytochrome P4501B1. (9497261)
1998
48
Evidence of HLA-linked susceptibility gene(s) in primary congenital glaucoma. (2088635)
1990
49
External trabeculotomy in the treatment of primary congenital glaucoma in Ghana. (6644642)
1983
50
Corneal changes in primary congenital glaucoma. (7257054)
1980

Variations for Primary Congenital Glaucoma

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Expression for genes affiliated with Primary Congenital Glaucoma

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Search GEO for disease gene expression data for Primary Congenital Glaucoma.

Pathways for genes affiliated with Primary Congenital Glaucoma

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GO Terms for genes affiliated with Primary Congenital Glaucoma

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Biological processes related to Primary Congenital Glaucoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1collagen fibril organizationGO:00301999.5CYP1B1, FOXC1

Sources for Primary Congenital Glaucoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet