MCID: PRM032
MIFTS: 29

Primary Congenital Glaucoma malady

Categories: Genetic diseases, Rare diseases, Eye diseases, Fetal diseases

Aliases & Classifications for Primary Congenital Glaucoma

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Aliases & Descriptions for Primary Congenital Glaucoma:

Name: Primary Congenital Glaucoma 23 24 68

Classifications:



Summaries for Primary Congenital Glaucoma

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MalaCards based summary: Primary Congenital Glaucoma is related to glaucoma 3a, primary open angle, congenital, juvenile, or adult onset and peters anomaly. An important gene associated with Primary Congenital Glaucoma is LTBP2 (Latent Transforming Growth Factor Beta Binding Protein 2). Affiliated tissues include eye, testes and brain, and related mouse phenotype vision/eye.

GeneReviews for NBK1135

Related Diseases for Primary Congenital Glaucoma

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Diseases in the Juvenile Glaucoma family:

Glaucoma 3, Primary Infantile, B Glaucoma 3, Primary Congenital, D
Glaucoma 3, Primary Congenital, C primary congenital glaucoma
Glaucoma Type 1c Glaucoma, Hereditary
Glaucoma, Hereditary Adult Type 1a Glaucoma, Hereditary Juvenile Type 1b
Glaucoma, Primary Infantile Type 3a Cyp1b1-Related Primary Congenital Glaucoma
Ltbp2-Related Primary Congenital Glaucoma Early-Onset Glaucoma

Diseases related to Primary Congenital Glaucoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 35)
idRelated DiseaseScoreTop Affiliating Genes
1glaucoma 3a, primary open angle, congenital, juvenile, or adult onset31.7CYP1B1, FOXC1, LTBP2, MYOC
2peters anomaly29.1CYP1B1, FOXC1, MYOC
3cyp1b1-related primary congenital glaucoma12.0
4ltbp2-related primary congenital glaucoma11.9
5glaucoma 3, primary congenital, d11.5
6glaucoma 3, primary infantile, b11.1
7glaucoma 1a, primary open angle10.2CYP1B1, MYOC
8familial hyperaldosteronism10.1CYP1B1, MYOC
9open-angle glaucoma10.0
10clonorchiasis10.0FOXC1, LTBP2
11buphthalmos10.0
12hypogonadotropic hypogonadism 24 without anosmia9.9CYP1B1, FOXC1
13paranasal sinus lymphoma9.9MYOC, WDR36
14larsen-like syndrome9.9CYP1B1, FOXC1
15secondary corneal edema9.8CYP1B1, LTBP2, MYOC
16retinitis9.8
17iritis9.8CYP1B1, MYOC
18chronic tympanitis9.8CYP1B1, FOXC1, LTBP2
19cataract9.8
20amyotrophic lateral sclerosis 129.7CYP1B1, MYOC, WDR36
21separation anxiety disorder9.7CYP1B1, MYOC, WDR36
22megalocornea9.6
23corneal edema9.6
24lens subluxation9.6
25patau syndrome9.6
26myopia9.6
27peripheral retinal degeneration9.6
28anisometropia9.6
29down syndrome9.6
30corneal dystrophy9.6
31retinal detachment9.6
32retinal degeneration9.6
33acute contagious conjunctivitis9.4CYP1B1, FOXC1, LTBP2, MYOC
34lactocele9.4CYP1B1, FOXC1, MYOC, WDR36
35primary trimethylaminuria7.7CYP1B1, FOXC1, GLC3B, GLC3C, LTBP2, MYOC

Graphical network of the top 20 diseases related to Primary Congenital Glaucoma:



Diseases related to primary congenital glaucoma

Symptoms & Phenotypes for Primary Congenital Glaucoma

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MGI Mouse Phenotypes related to Primary Congenital Glaucoma according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053918.7CYP1B1, FOXC1, LTBP2, MYOC

Drugs & Therapeutics for Primary Congenital Glaucoma

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Drugs for Primary Congenital Glaucoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 36)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Bevacizumabapproved, investigationalPhase 41968216974-75-3
Synonyms:
216974-75-3
Avastin
Avastin (TN)
Bevacizumab
Bevacizumab (genetical recombination)
 
Bevacizumab (genetical recombination) (JAN)
D06409
R-435
anti-VEGF monoclonal antibody
antiVEGF
bevacizumab
2Angiogenesis InhibitorsPhase 4, Phase 24143
3Angiogenesis Modulating AgentsPhase 44072
4
TimololapprovedPhase 225226839-75-833624, 5478
Synonyms:
(-)-3-Morpholino-4-(3-tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole
(2S)-1-((1,1-dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-2-propanol
(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
(2S)-1-[(1,1-dimethylethyl)amino]-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
(S)-1-(1,1-(Dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-2-propanol
(S)-1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol
(S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
(S)-timolol
131628-37-0
194288-09-0
26839-75-8
26921-17-5 (maleate (1:1) salt)
AB00513729
AC1L1PYN
AC1Q59QM
Apo-Timol
Apo-Timop
Aquanil
BIDD:GT0073
BPBio1_001008
BRD-K08806317-050-03-6
BSPBio_000916
Betim
Betimol
Betimol (TN)
Blocadren
C07141
C13H24N4O3S
CAS-26921-17-5
CHEBI:9599
CHEMBL499
CID33624
CPD001456519
D08600
DB00373
DB08625
EINECS 248-032-6
HMS2089I11
HSDB 6533
Istalol
L-714,465
LS-122231
Lopac-T-6394
Lopac0_001189
MK-950
NCGC00016038-01
 
NCGC00016038-02
NCGC00016798-01
NCGC00016798-07
NCGC00022033-02
NCGC00022033-04
NCGC00022033-05
Novo-Timol
Nu-Timolol
Oprea1_640981
Optimol
Phoxal-timolol
Prestwick0_000948
Prestwick1_000948
Prestwick2_000948
Prestwick3_000948
Proflax
S(-)-Timolol maleate
S-(-)-3-(3-tert-Butylamino-2-hydroxypropoxy)-4-morpholino-1,2,5-thiadiazole
SAM002564238
SPBio_003075
ST072193
TIM
Temserin
Tenopt
Tim-AK
Timacar
Timacor
Timolol
Timolol (INN)
Timolol (TN)
Timolol GFS
Timolol Maleate, (1:1) Salt
Timolol [USAN]
Timolol anhydrous
Timolol maleate
Timololo
Timololum
Timololum [INN-Latin]
Timopic
Timoptic
Timoptic OcuDose
Timoptic in Ocudose
Timoptic-XE
Timoptol
Tocris-0649
UNII-817W3C6175
timolol
5Ophthalmic SolutionsPhase 21092
6Pharmaceutical SolutionsPhase 27793
7TetrahydrozolinePhase 2593
8Neurotransmitter AgentsPhase 217734
9TEMPOPhase 227
10Adrenergic AntagonistsPhase 21535
11Antihypertensive AgentsPhase 24095
12Adrenergic beta-AntagonistsPhase 21154
13Adrenergic AgentsPhase 25140
14Anti-Arrhythmia AgentsPhase 22969
15Aluminum hydroxide, magnesium hydroxide, simethicone drug combinationPhase 227
16
Dexamethasoneapproved, investigational, vet_approved208450-02-25743
Synonyms:
(3H)-Dexamethasone
.delta.(sup 1)-9-.alpha.-Fluoro-16-.alpha.-methylcortisol
.gamma.corten
1-Dehydro-16.alpha.-methyl-9.alpha.-fluorohydrocortisone
1-Dehydro-16alpha -methyl-9alpha -fluorohydrocortisone
1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone
1-Dehydro-16α-methyl-9α-fluorohydrocortisone
137098-19-2
16-alpha-Methyl-9-alpha-fluoro-1-dehydrocortisol
16-alpha-Methyl-9-alpha-fluoro-delta(sup 1)-hydrocortisone
16-alpha-Methyl-9-alpha-fluoro-delta1-hydrocortisone
16-alpha-Methyl-9-alpha-fluoroprednisolone
16.alpha.-Methyl-9.alpha.-fluoro-1-dehydrocortisol
16.alpha.-Methyl-9.alpha.-fluoroprednisolone
16alpha -Methyl-9alpha -fluoro-1-dehydrocortisol
16alpha -Methyl-9alpha -fluoroprednisolone
16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol
16alpha-Methyl-9alpha-fluoro-delta(sup 1)-hydrocortisone
16alpha-Methyl-9alpha-fluoroprednisolone
16α-Methyl-9α-fluoro-1-dehydrocortisol
23495-06-9
31375_FLUKA
46165_FLUKA
46165_RIEDEL
50-02-2
8054-59-9
9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11alpha -methylpregna-1,4-diene-3,20-dione
9-Fluoro-16-methylprednisolone
9-alpha-Fluoro-16-alpha-methylprednisolone
9.alpha.-Fluoro-16.alpha.-methylprednisolone
906422-84-2
9A-FLUORO-16BETA-METHYLPREDNISOLONE
9alpha -Fluoro-16alpha -methylprednisolone
9alpha-Fluoro-16alpha-methylprednisolone
9alpha-fluoro-16alpha-methyl-Prednisolone
9α-Fluoro-16α-methylprednisolone
AC-11056
AC1L1L1H
AC1Q29DM
AI3-50934
Adexone
Aeroseb-D
Aeroseb-Dex
Aeroseb-dex
Ak Dex Oph Otic Soln 0.1%
Alcon Brand of Dexamethasone
Anaflogistico
Aphtasolon
Aphthasolone
Apo-dexamethasone
Auxiron
Azimycin (veterinary)
Azium
Azium (Veterinary)
Azium (veterinary)
BIDD:ER0494
BIDD:PXR0060
BRD-K38775274-001-02-3
BRD-K38775274-001-06-4
BSPBio_000995
Bisu DS
Bisu Ds
C15643
C22H29FO5
CCRIS 7067
CHEBI:41879
CHEMBL384467
CID5743
CPD-10549
CPD001227192
Calonat
Corson
Corsone
Cortisumman
D00292
D003907
D1756_SIGMA
D4902_SIGMA
D6645_SIGMA
D8893_SIGMA
D9184_SIGMA
DB01234
DEX
DEXA
DEXONE 0.5
DEXONE 0.75
DEXONE 1.5
DEXONE 4
DXM
DXMS
Decacort
Decacortin
Decaderm
Decadron
Decadron (TN)
Decadron Tablets, Elixir
Decadron, Dexamethasone
Decadron-LA
Decadron-La
Decagel
Decaject
Decaject L.A.
Decaject-L.A.
Decalix
Decameth
Decasone
Decaspray
Dectancyl
Dekacort
Delta1-9alpha-Fluoro-16alpha-methylcortisol
Deltafluorene
Dergramin
Deronil
Desadrene
Desametasone
Desametasone [DCIT]
Desametasone [Dcit]
Desamethasone
Desameton
Deseronil
Dex-Ide
Dex-ide
Dexa
Dexa Mamallet
Dexa mamallet
Dexa-Cortidelt
Dexa-Cortisyl
Dexa-Mamallet
Dexa-Scheroson
Dexa-Sine
Dexa-cortidelt
Dexa-cortisyl
Dexa-scheroson
Dexa-sine
Dexacen-4
Dexacidin
Dexacort
Dexacortal
Dexacortin
Dexadeltone
Dexafarma
Dexair
Dexalona
Dexaltin
Dexametasona
Dexametasona [INN-Spanish]
Dexametasone
 
Dexameth
Dexamethansone
Dexamethasone
Dexamethasone (JP15/USP/INN)
Dexamethasone Acetate
Dexamethasone Alcohol
Dexamethasone Base
Dexamethasone Intensol
Dexamethasone Sodium Phosphate
Dexamethasone [INN:BAN:JAN]
Dexamethasone alcohol
Dexamethasone base
Dexamethasone intensol
Dexamethasone-omega
Dexamethasonum
Dexamethasonum [INN-Latin]
Dexamethazone
Dexamonozon
Dexapolcort
Dexapos
Dexaprol
Dexason
Dexasone
Dexasone 0.5mg
Dexasone 0.75mg
Dexasone 4mg
Dexasporin
Dexinolon
Dexinoral
Dexone
Dexone 0.5
Dexone 0.75
Dexone 1.5
Dexone 4
Dexonium
Dexpak
Dextelan
Dezone
Dinormon
Dxms
ECR Brand of Dexamethasone
EINECS 200-003-9
FT-0080377
Fluormethylprednisolone
Fluormone
Fluorocort
Fortecortin
Foy Brand of Dexamethasone
Gammacorten
HL-dex
HMS1792A17
HMS1990A17
HMS2089N13
HSDB 3053
Hexadecadrol
Hexadrol
Hexadrol Elixir
Hexadrol Tablets
Hexadrol elixir
Hl-Dex
Hl-dex
I06-1196
ICN Brand of Dexamethasone
IontoDex
Isopto-Dex
Isopto-dex
LS-7300
Lokalison F
Lokalison f
Loverine
Luxazone
MK 125
MLS001055412
MLS001332507
MLS001332508
Maxidex
Maxidex Ont 0.1%
Maxidex Sus 0.1%
Maxitrol
Mediamethasone
Merck Brand of Dexamethasone
Merz Brand 1 of Dexamethasone
Merz Brand 2 of Dexamethasone
Methylfluorprednisolone
Mexidex
Millicorten
MolMap_000018
MolPort-003-846-433
Mymethasone
NCGC00091019-01
NCGC00091019-02
NCGC00091019-03
NCGC00091019-04
NCGC00091019-05
NCI60_003067
NSC 34521
NSC34521
Naquasone (veterinary)
Neomycin and polymyxin b sulfates and dexamethasone
Neomycin and polymyxin b sulphates and dexamethasone
OTO-104
Ocu-Trol
Ocu-trol
Oradexon
PHL-dexamethasone
PMS-dexamethasone
Pet Derm III
Pet Derm Iii
Pet derm III
Pet-Derm Iii
Pms Dexamethasone Elixir 0.5mg/5ml
Policort
Posurdex
Prednisolon F
Prednisolon f
Prednisolone F
Prednisolone f
Prodex
S1322_Selleck
SAM002548948
SGCUT00126
SK-Dexamethasone
SK-dexamethasone
SMP1_000092
SMR000857119
SMR001227192
ST50307091
Sandoz dexamethasone
Sk-Dexamethasone
Spectrum5_002019
Spoloven
Sunia Sol D
Sunia sol D
Superprednol
TL8003317
Tobradex
Tobramycin and dexamethasone
Tresaderm (veterinary)
Turbinaire
UNII-7S5I7G3JQL
Visumetazone
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ G1
ZINC03875332
alpha -Fluoro-16-alpha -methylcortisol
delta(Sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta(sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta1-9alpha-Fluoro-16alpha-methylcortisol
dexamethasone
nchembio809-comp2
to_000038
17
Mentholapproved23532216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Caswell No. 540
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
DivK1c_000820
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
FEMA No. 2665
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
HMS1922G13
HMS2092L14
HMS502I22
 
HSDB 5662
HSDB 593
Headache crystals
Hexahydrothymol
I06-1216
I14-7371
IDI1_000820
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Menthomenthol
Menthyl alcohol
MolPort-000-849-729
MolPort-001-793-392
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Neoisomenthol
Peppermint camphor
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
ZINC01482164
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol
18Hormones13979
19Hormone Antagonists12778
20HIV Protease Inhibitors5319
21Hormones, Hormone Substitutes, and Hormone Antagonists12767
22Peripheral Nervous System Agents22776
23Immunoglobulins6045
24Antibodies6045
25
protease inhibitors5320
Synonyms:
 
protease inhibitors
26glucocorticoids4920
27Anti-Inflammatory Agents10355
28Antineoplastic Agents, Hormonal5407
29Antiemetics3888
30Anesthetics9001
31Autonomic Agents9774
32BB 11012084
33Dexamethasone acetate20841177-87-3
34Dexamethasone 21-phosphate2084
35Central Nervous System Depressants12806
36Gastrointestinal Agents8109

Interventional clinical trials:

(show all 21)
idNameStatusNCT IDPhase
1Comparison of the Ahmed Glaucoma Valve FP7 and FP8 in Pediatric GlaucomaUnknown statusNCT01494974Phase 4
2Use of Bevacizumab in Trabeculectomy SurgeryCompletedNCT01166594Phase 4
3Aphakia Versus Pseudophakia in Children Under 2 Years Undergoing Bilateral Congenital Cataract SurgeryCompletedNCT01297153Phase 4
4Efficacy of a Timolol Nasal Spray as a Treatment for Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT) - (TEMPO)RecruitingNCT02484716Phase 2
5Comparison Between Deep Sclerectomy and Traditional Trabeculotomy & Trabeculectomy in Congenital GlaucomaUnknown statusNCT01460017Phase 1
6Combined Trab+Trab Versus Combined Trab+Trab With Subconjunctival Implantation of Ologen for Primary Congenital GlaucomaActive, not recruitingNCT02121171Phase 1
7The Genetic Characteristics in South Korean Patients With Primary Congenital GlaucomaUnknown statusNCT01020721
8Endoscopic Goniotomy for Infantile GlaucomaCompletedNCT00338533
9Mechanism of Aphakic and Pseudophakic Glaucoma in Pediatric PatientsCompletedNCT01136473
10Quality of Life in Children Glaucoma and CataractCompletedNCT02490267
11Long-term Postoperative Outcomes After Bilateral Congenital Cataract Surgery in Eyes With MicrophthalmosCompletedNCT01818037
12Effect of the Timing of Cataract Surgery on Complications in Patients With Bilateral Congenital CataractsCompletedNCT02581046
13Incidence of Ocular Antibodies in Patients With Sturge - Weber Syndrome (SWS)CompletedNCT00610402
14Clinical Trial : Complications of in the Bag IOL Versus Optic Capture of IOL in Pediatric Cataract SurgeryCompletedNCT02491918
15Genetic Testing in Primary Congenital Glaucoma PatientsRecruitingNCT01136460
16Aqueous Humor Dynamics and Biometric Parameters in Eyes of ChildrenRecruitingNCT01290588
17OCT-guided LALAK in ChildrenRecruitingNCT01579643
18Safety and Performance Study of the ARGOS-IO System in Patients Undergoing Boston Keratoprosthesis ImplantationActive, not recruitingNCT02945176
19Study of an Intervention to Improve Problem List Accuracy and UseActive, not recruitingNCT01105923
20Determination of the Sensitivity and Specificity of a Smartphone Application to Detect RetinoblastomaNot yet recruitingNCT03016156
21Repository for Inherited Eye DiseasesSuspendedNCT00378742

Search NIH Clinical Center for Primary Congenital Glaucoma

Genetic Tests for Primary Congenital Glaucoma

About this section

Genetic tests related to Primary Congenital Glaucoma:

id Genetic test Affiliating Genes
1 Primary Congenital Glaucoma24 LTBP2

Anatomical Context for Primary Congenital Glaucoma

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MalaCards organs/tissues related to Primary Congenital Glaucoma:

36
Eye, Testes, Brain

Publications for Primary Congenital Glaucoma

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Articles related to Primary Congenital Glaucoma:

(show top 50)    (show all 236)
idTitleAuthorsYear
1
Outcomes of microcatheter-assisted trabeculotomy following failed angle surgeries in primary congenital glaucoma. (27740616)
2017
2
Screening of the LTBP2 gene in 214 Chinese sporadic CYP1B1-negative patients with primary congenital glaucoma. (27293371)
2016
3
Surgical Outcomes of Trabeculotomy in Newborns with Primary Congenital Glaucoma. (27625089)
2016
4
CYP1B1 mutational screening in a Portuguese cohort of primary congenital glaucoma patients. (27268095)
2016
5
CYP1B1 Mutations in Individuals With Primary Congenital Glaucoma and Residing in Denmark. (27820421)
2016
6
Corneal Haze as Prognostic Indicator of Intraocular Pressure in Primary Congenital Glaucoma. (27367136)
2016
7
Persistent Corneal Edema Associated With Subconjunctival 5-fluorouracil in an Infant With Primary Congenital Glaucoma. (27783089)
2016
8
A spectrum of CYP1B1 mutations associated with primary congenital glaucoma in families of Pakistani descent. (27508083)
2016
9
Primary Congenital Glaucoma versus Glaucoma Following Congenital Cataract Surgery: Comparative Clinical Features and Long-term Outcomes. (27544478)
2016
10
Combined trabeculotomy-trabeculectomy versus Ahmed valve implantation for refractory primary congenital glaucoma in Egyptian patients: a long-term follow-up. (27053995)
2016
11
A case of spontaneously resolved primary congenital glaucoma. (27050360)
2016
12
Structural and biomechanical corneal differences between patients suffering from primary congenital glaucoma and healthy volunteers. (27573413)
2016
13
Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity. (27270174)
2016
14
Fiberoptic Microcatheter-assisted 360-Degree Trabeculotomy Ab Externo After Unsuccessful Trabeculotome Trabeculotomy in Primary Congenital Glaucoma: A Case Report. (27367133)
2016
15
Observations regarding gender and response to initial angle surgery in CYP1B1-related primary congenital glaucoma. (27438756)
2016
16
Surgical outcomes in children with primary congenital glaucoma: a 20-year experience. (27033964)
2016
17
Pathological and Immunohistochemical Alterations of the Cornea in Congenital Corneal Opacification Secondary to Primary Congenital Glaucoma and Peters Anomaly. (26684044)
2016
18
Construction of CYP1B1 gene haplotypes predisposing to primary congenital glaucoma through allele-specific PCR/restriction fragment length polymorphism analysis]. (26663047)
2015
19
Surgical interventions for primary congenital glaucoma. (25636153)
2015
20
Genotype-Phenotype Correlations in CYP1B1-Associated Primary Congenital Glaucoma Patients Representing Two Large Cohorts from India and Brazil. (25978063)
2015
21
Mitochondrial transfer RNA variants and primary congenital glaucoma. (25835039)
2015
22
Combined trabeculotomy-trabeculectomy with antimetabolite and releasable suture: outcome with primary congenital glaucoma in a north Indian population. (26695601)
2015
23
CYP1B1 copy number variation is not a major contributor to primary congenital glaucoma. (25750510)
2015
24
The Genetics and the Genomics of Primary Congenital Glaucoma. (26451367)
2015
25
Intraocular pressure measurement by three different tonometers in primary congenital glaucoma. (26005552)
2015
26
Surgical results of trabeculectomy and ahmed valve implantation following a previous failed trabeculectomy in primary congenital glaucoma patients. (25829827)
2015
27
CYP1B1 and MYOC Mutations in Vietnamese Primary Congenital Glaucoma Patients. (26550974)
2015
28
A case of spontaneously resolved primary congenital glaucoma. (26458483)
2015
29
Outcomes of Ahmed glaucoma valve implantation in advanced primary congenital glaucoma with previous surgical failure. (26082610)
2015
30
Clinical Variability of Primary Congenital Glaucoma in a Spanish Family With Cyp1b1 Gene Mutations. (25836661)
2015
31
Primary Congenital Glaucoma with Delayed Suprachoroidal Hemorrhage following Combined Trabeculotomy Trabeculectomy and 5-Fluorouracil. (26819790)
2015
32
CYP1B1-mediated Pathobiology of Primary Congenital Glaucoma. (26997841)
2015
33
Primary congenital glaucoma. (26518078)
2015
34
CYP1B1 gene mutations with incomplete penetrance in a Chinese pedigree with primary congenital glaucoma: a case report and review of literatures. (26550445)
2015
35
Outcomes of Ahmed valve implant following a failed initial trabeculotomy and trabeculectomy in refractory primary congenital glaucoma. (25624676)
2015
36
PERIPHERAL RETINAL DEGENERATIONS AND RHEGMATOGENOUS DETACHMENT IN PRIMARY CONGENITAL GLAUCOMA. (26200515)
2015
37
Gonioscopy assisted transluminal trabeculotomy: an ab interno circumferential trabeculotomy for the treatment of primary congenital glaucoma and juvenile open angle glaucoma. (25677669)
2015
38
Long-term outcome of primary congenital glaucoma in South Korea. (26361375)
2015
39
CYP1B1 gene analysis and phenotypic correlation in Portuguese children with primary congenital glaucoma. (25952714)
2015
40
Homozygous p.G61E mutation in a consanguineous Pakistani family with co-existence of juvenile-onset open angle glaucoma and primary congenital glaucoma. (26164761)
2015
41
Genotype-phenotype correlation in moroccan patients with primary congenital glaucoma. (25826643)
2015
42
Long-term Surgical Outcomes of 180-Degree Suture Trabeculotomy in Korean Patients With Primary Congenital Glaucoma. (26550978)
2015
43
Phenotype and Genotype Correlation in Iranian Primary Congenital Glaucoma Patients. (25580891)
2015
44
Illuminated microcatheter circumferential trabeculotomy versus combined trabeculotomy-trabeculectomy for primary congenital glaucoma: a randomized controlled trial. (25486542)
2015
45
Primary Congenital Glaucoma Outcomes: Lessons From 23 Years of Follow-up. (25634533)
2015
46
A rare case of primary congenital glaucoma in combination with neurofibromatosis 1: a case report. (26514695)
2015
47
Boston type 1 keratoprosthesis for primary congenital glaucoma. (26206789)
2015
48
Results of Ahmed glaucoma valve implantation in primary congenital glaucoma. (26198016)
2015
49
Review on the Management of Primary Congenital Glaucoma. (26997844)
2015
50
Intraocular pressure and biomechanical corneal properties measure by ocular response analyser in patients with primary congenital glaucoma. (26647905)
2015

Variations for Primary Congenital Glaucoma

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Expression for genes affiliated with Primary Congenital Glaucoma

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Search GEO for disease gene expression data for Primary Congenital Glaucoma.

Pathways for genes affiliated with Primary Congenital Glaucoma

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GO Terms for genes affiliated with Primary Congenital Glaucoma

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Biological processes related to Primary Congenital Glaucoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1collagen fibril organizationGO:00301999.5CYP1B1, FOXC1

Sources for Primary Congenital Glaucoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet