PMA
MCID: PRG001
MIFTS: 39

Progressive Muscular Atrophy (PMA) malady

Categories: Neuronal diseases, Rare diseases, Muscle diseases, Bone diseases

Aliases & Classifications for Progressive Muscular Atrophy

About this section
Sources:
11Disease Ontology, 13DISEASES, 30ICD10, 31ICD10 via Orphanet, 32ICD9CM, 39MeSH, 45NCIt, 50Novoseek, 54Orphanet, 62SNOMED-CT, 68UMLS
See all MalaCards sources

Aliases & Descriptions for Progressive Muscular Atrophy:

Name: Progressive Muscular Atrophy 11 54 50 13 68
Progressive Spinal Muscular Atrophy 11
 
Pure Progressive Muscular Atrophy 11
Pma 54

Characteristics:

Orphanet epidemiological data:

54
progressive muscular atrophy:
Inheritance: Not applicable; Age of onset: Adult; Age of death: adult,elderly

Classifications:



External Ids:

Disease Ontology11 DOID:318
ICD1030 G12.21
ICD9CM32 335.21
MeSH39 D009134
SNOMED-CT62 88923002
NCIt45 C85027
Orphanet54 ORPHA454706
ICD10 via Orphanet31 G12.2

Summaries for Progressive Muscular Atrophy

About this section
Wikipedia:71 Progressive muscular atrophy (PMA), also known as Duchenne-Aran muscular atrophy and by various other... more...

MalaCards based summary: Progressive Muscular Atrophy, also known as progressive spinal muscular atrophy, is related to adult progressive spinal muscular atrophy aran duchenne type and motor neuron disease. An important gene associated with Progressive Muscular Atrophy is SMN1 (Survival Of Motor Neuron 1, Telomeric). Affiliated tissues include spinal cord and brain, and related mouse phenotypes are muscle and cellular.

Related Diseases for Progressive Muscular Atrophy

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Diseases in the Muscular Atrophy family:

progressive muscular atrophy

Diseases related to Progressive Muscular Atrophy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 55)
idRelated DiseaseScoreTop Affiliating Genes
1adult progressive spinal muscular atrophy aran duchenne type12.1
2motor neuron disease11.1
3spinal muscular atrophy11.1
4spinal atrophy ophthalmoplegia pyramidal syndrome11.1
5spinal muscular atrophy-110.9
6myopathy, distal, tateyama type10.7
7spinal muscular atrophy, distal, congenital nonprogressive10.7
8muscular atrophy10.6
9posterior polar cataract10.2SMN1, SMN2
10shigellosis10.2SMN1, SMN2
11pigmented nodular adrenocortical disease, primary, 310.2SMN1, SMN2
12spinal muscular atrophy-410.2SMN1, SMN2
13bipolar ll disorder10.2SMN1, SMN2
14cardiac tuberculosis10.2SMN1, SMN2
15sandhoff disease, infantile, juvenile, and adult forms10.1SMN1, SMN2
16pseudohermaphrodism anorectal anomalies10.1SMN1, SMN2
17lateral sclerosis10.1
18spinal muscular atrophy-310.1SMN1, SMN2
19phototoxic dermatitis10.1SMN1, SMN2, TRPV4
20bladder urachal adenocarcinoma10.1SMN1, SMN2, TRPV4
21spondylolisthesis10.0SMN1, SMN2, TRPV4
22neuronitis10.0
23cerebral angioma10.0CAV3, SMN1, SMN2
24osteogenesis imperfecta, type vi10.0C9orf72, TARDBP
25sting-associated vasculopathy, infantile-onset9.9C9orf72, TARDBP
26severe congenital nemaline myopathy9.9C9orf72, TARDBP
27andersen syndrome9.9C9orf72, TARDBP
28chorioamnionitis9.9C9orf72, TARDBP
29multifocal motor neuropathy9.9
30poliomyelitis9.9
31neuropathy9.9
32adult mesenchymal chondrosarcoma9.9C9orf72, TARDBP
33colorado tick fever9.9SMN1, SMN2, TARDBP
34mitochondrial dna depletion syndrome 39.9C9orf72, TARDBP
35pancreatic solid pseudopapillary carcinoma9.8C9orf72, TARDBP
36hypoproteinemia, hypercatabolic9.8C9orf72, SMN1, TARDBP
37muscular dystrophy9.8
38lissencephaly 6, with microcephaly9.8LMNB1, TARDBP
39pancreatic cancer/melanoma syndrome9.8C9orf72, TARDBP
40autoimmune disease of urogenital tract9.7C9orf72, TARDBP
41mucopolysaccharidosis iv9.7C9orf72, SMN1, SMN2, TARDBP
42substance-induced psychosis9.7C9orf72, SMN1, SMN2, TARDBP
43charcot-marie-tooth disease9.7
44myasthenia gravis9.7
45tooth disease9.7
46porphyria9.7
47addison's disease9.7
48candidiasis9.7
49klinefelter's syndrome9.7
50encephalitis9.7

Graphical network of the top 20 diseases related to Progressive Muscular Atrophy:



Diseases related to progressive muscular atrophy

Symptoms & Phenotypes for Progressive Muscular Atrophy

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MGI Mouse Phenotypes related to Progressive Muscular Atrophy according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053698.8CAV3, LMNB1, SMN2, TARDBP, TRPV4
2MP:00053848.0AIRE, C9orf72, CAV3, LMNB1, SMN2, TARDBP
3MP:00053767.5AIRE, C9orf72, CAV3, LMNB1, SMN2, TARDBP
4MP:00036317.3AIRE, C9orf72, LMNB1, SMN2, TARDBP, TRPV4

Drugs & Therapeutics for Progressive Muscular Atrophy

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Drugs for Progressive Muscular Atrophy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 113)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
MethyltestosteroneapprovedPhase 4, Phase 3, Phase 256358-18-46010
Synonyms:
17(alpha)-Methyl-delta(4)-androsten-17(beta)-ol-3-one
17-Methyltestosterone
17-beta-Hydroxy-17-methylandrost-4-en-3-one
17-methyltestosterone
17alpha-Methyl-3-oxo-4-androsten-17beta-ol
17alpha-Methyl-delta(4)-androsten-17beta-ol-3-one
17alpha-Methyltestosterone
17alpha-methyl-delta-androsten-17beta-ol-3-one
17alpha-methyltestosterone
 
17beta-Hydroxy-17-methylandrost-4-en-3-one
17α-methyl-Δ4-androsten-17β-ol-3-one
17α-methyltestosterone
4-Androstene-17alpha-methyl-17beta-ol-3-one
Android
Methyltestosterone
Methyltestosteronum
Metiltestosterona
NSC-9701
Testred
Virilon
2
Testosteroneapproved, investigationalPhase 4, Phase 3, Phase 256358-22-06013
Synonyms:
(+)-testosterone
(+-)-8-iso-testosterone
(+-)-retrotestosterone
(+-)-testosterone
(17b)-17-hydroxy-androst-4-en-3-one
(17beta)-17-Hydroxyandrost-4-en-3-one
(8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
13-Iso-testosterone
17-Hydroxy-(17-beta)-androst-4-en-3-one
17-Hydroxy-(17beta)-androst-4-en-3-one
17-Hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one
17-Hydroxy-D4-androsten-3-one
17-Hydroxy-androst-4-en-3-one
17-beta-Hydroxy-delta(sup 4)-androsten-3-one
17-beta-Hydroxyandrost-4-en-3-one
17?-Hydroxy-4-androsten-3-one
17a-Hydroxy-(13a)-androst-4-en-3-one
17a-Hydroxy-13a-androst-4-en-3-one
17a-Hydroxy-14b-androst-4-en-3-one
17a-Hydroxy-androst-4-en-3-one
17b-Hydroxy-(10a)-androst-4-en-3-one
17b-Hydroxy-(13a)-androst-4-en-3-one
17b-Hydroxy-(8a)-androst-4-en-3-one
17b-Hydroxy-(8a,10a)-androst-4-en-3-one
17b-Hydroxy-(9b)-androst-4-en-3-one
17b-Hydroxy-(9b,10a)-androst-4-en-3-one
17b-Hydroxy-13a-androst-4-en-3-one
17b-Hydroxy-8a-androst-4-en-3-one
17b-Hydroxy-D4-androsten-3-one
17b-Hydroxy-androst-4-en-3-on
17b-Hydroxy-androst-4-en-3-one
17b-Hydroxyandrost-4-en-3-one
17b-Hydroxyandrost-4-ene-3-one
17b-Testosterone
17b-hydroxy-4-androsten-3-one
17beta-Hydroxy-3-oxo-4-androstene
17beta-Hydroxy-4-androsten-3-one
17beta-Hydroxy-delta(sup4)-androsten-3-one
17beta-Hydroxyandrost-4-en-3-one
17beta-Hydroxyandrost-4-ene-3-one
17beta-hydroxy-4-androsten-3-one
4-Androsten-17?-ol-3-one
4-Androsten-17beta-ol-3-one
4-Androsten-3-one-17b-ol
4-androsten-17β-ol-3-one
4-androstene-17beta-ol-3-one
46923_FLUKA
46923_RIEDEL
58-22-0
7-beta-Hydroxyandrost-4-en-3-one
8-Iso-testosterone
9b,10a-Testosterone
9b-Testosterone
AA 2500
AC-14899
AC1L1LM0
Andriol
Andro
Andro 100
Andro L.A. 200
AndroGel
Androderm
Androderm (TN)
Androgel
Androgel (TN)
Android 10
Android 25
Android 5
Androlin
Andronaq
Andronate 100
Andronate 200
Andropatch
Andropository 200
Androsorb
Androst-4-en-17b-ol-3-one
Androst-4-en-17beta-ol-3-one
Androst-4-ene-17b-ol-3-one
Andrusol
Andryl 200
B5DEE83F-632B-48A1-A0ED-A51E7F13DF2E
BIDD:ER0555
BIM-0061761.0001
Beta Testosterone
Bio-0678
Bio-T-Gel
C00535
CCRIS 574
CDB 111C
CHEBI:17347
CHEMBL386630
CID6013
CMC_13449
COL 1621
CP 601B
CPD000058344
Cristerona T
Cristerone T
D00075
D4-Androsten-17b-ol-3-one
DB00624
Dea No. 4000
Delatest
Delatestryl
Depo-Testadiol
Depo-Testosterone
Depo-Testosterone Cypionate
Depotest
EINECS 200-370-5
Epitestosteron
Everone 200
Geno-Cristaux Gremy
Geno-cristaux Gremy
Geno-cristaux gremy
HMS2052N11
HSDB 3398
Halotensin
Homosteron
Homosterone
 
Intrinsa
LMST02020002
LS-148813
LibiGel
Libigel
Lumitestosteron
MLS000563091
MLS001032098
MLS001306401
MLS002174283
Malerone
Malestrone
Malestrone (amps)
Malogen in Oil
Malogen, Aquaspension Injection
Malogen, aquaspension injection
Mertestate
Metandren
Methyltestosterone
MolPort-002-506-901
NCGC00091018-01
NSC 9700
Neo-Hombreol F
Neo-Testis
Neo-testis
Neotestis
Oreton
Oreton F
Oreton Methyl
Oreton-F
Orquisteron
Perandren
Percutacrine Androgenique
Percutacrine androgenique
Primotest
Primoteston
Rac-17b-hydroxy-(13a)androst-4-en-3-one
Rac-17b-hydroxy-(8a)-androst-4-en-3-one
Rac-17b-hydroxy-(9b,10a)androst-4-en-3-one
Rac-17b-hydroxy-androst-4-en-3-one
Relibra
Retrotestosterone
S00309
S2033_Selleck
SAM001246921
SMR000058344
SMR001261453
Scheinpharm Testone-Cyp
Striant
Striant (TN)
Sustanon
Sustanone
Sustason 250
Synandrol F
T-Cypionate
T1500_SIGMA
T5411_FLUKA
T5411_SIGMA
TES
Teslen
Testamone 100
Testandrone
Testaqua
Testiculosterone
Testim
Testim (TN)
Testobase
Testoderm
Testoderm Tts
Testogel
Testoject-50
Testolent
Testolin
Testopel Pellets
Testopropon
Testosteroid
Testosteron
Testosterona
Testosterona [INN-Spanish]
Testosterone
Testosterone (JAN/USP)
Testosterone Cypionate
Testosterone Enanthate
Testosterone Hydrate
Testosterone [Androgenic steroids, anabolic]
Testosterone [INN:BAN]
Testosterone and its esters
Testosterone hydrate
Testosterone solution
Testosteronum
Testosteronum [INN-Latin]
Testostosterone
Testostérone
Testoviron
Testoviron Schering
Testoviron T
Testoxyl
Testred
Testred Cypionate 200
Testrin-P.A
Testro AQ
Testro Aq
Testrone
Testryl
Tostrelle
Tostrex
Trans-Testosterone
UNII-3XMK78S47O
Viatrel
Virilon
Virilon IM
Virormone
Virosterone
ZINC06500184
beta testosterone
delta(sup 4)-Androsten-17(beta)-ol-3-one
delta4-Androsten-17beta-ol-3-one
delta4-androsten-17b-ol-3-one
testosterone
trans-Testosterone
3Testosterone 17 beta-cypionatePhase 4, Phase 3, Phase 2563
4
Testosterone enanthatePhase 4, Phase 3, Phase 2563315-37-79416
Synonyms:
17-((1-Oxoheptyl)oxy)androst-4-en-3-one
17-Hydroxyandrost-4-en-3-one, 17-heptanoate
17-Hydroxyandrost-4-en-3-one, 17-heptanoic acid
17beta-Enanthoxyandrost-4-en-3-one
17beta-Hydroxyandrost-4-en-3-one enanthate
4-Androsten-17beta-ol-3-one 17-enanthate
4-Androsten-3-one 17beta-enanthate
Androgyn L.A.
Andropository
Androtardyl
Atlatest
DEA No. 4000
DePatestrye
Delatest
Delatestryl
Depo-Testro Med
Ditate
Durathate
Everone
 
Exten test
Malogen L.A.
Malogen L.A.200
Orquisteron-E
Primotestone
Reposo TMD
Testanthate
Testate
Testenate
Testinon
Testoenant
Testonenant
Testosterone 17-enanthate
Testosterone 17beta-heptanoate
Testosterone 17beta-heptanoic acid
Testosterone enantate
Testosterone heptoate
Testosterone heptoic acid
Testosterone heptylate
Testosterone oenanthate
Testostroval
5Anabolic AgentsPhase 4, Phase 3, Phase 2513
6Testosterone undecanoatePhase 4, Phase 3, Phase 2563
7AndrogensPhase 4, Phase 3, Phase 21321
8Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 3, Phase 2, Phase 113168
9Antineoplastic Agents, HormonalPhase 4, Phase 3, Phase 2, Phase 15592
10HormonesPhase 4, Phase 3, Phase 2, Phase 114415
11Hormone AntagonistsPhase 4, Phase 3, Phase 2, Phase 113180
12
HydroxyureaapprovedPhase 2, Phase 3, Phase 1223127-07-13657
Synonyms:
1-HYDROXYUREA
127-07-1
4-03-00-00170 (Beilstein Handbook Reference)
55291_FLUKA
AC1L1GF8
AC1Q4ZXK
AI3-51139
BB_SC-7256
BRN 1741548
BSPBio_002164
Bio1_000451
Bio1_000940
Bio1_001429
Biosupressin
C07044
CCRIS 958
CHEBI:44423
CHEMBL467
CID3657
Carbamohydroxamic Acid
Carbamohydroxamic acid
Carbamohydroximic Acid
Carbamohydroximic acid
Carbamohydroxyamic Acid
Carbamohydroxyamic acid
Carbamoyl Oxime
Carbamoyl oxime
Carbamyl Hydroxamate
Carbamyl hydroxamate
Carrbamoyl Oxime
D00341
D006918
DB01005
DRG-0253
DivK1c_000556
Droxia
Droxia (TM)
Droxia (TN)
E0723DBA-5AF3-49D1-B5F6-59420AB87AC9
EINECS 204-821-7
EU-0100596
FT-0083575
H 8627
H0310
H20210
H8627_SIGMA
HMS1920F09
HMS2091L17
HMS501L18
HSDB 6887
HU
HYDREA (TN)
HYDROXY-UREA
Hidrix
Hidroxicarbamida
Hidroxicarbamida [INN-Spanish]
Hydrea
Hydrea (TM)
Hydrea, Biosupressin, Cytodrox, Hydroxyurea
Hydreia
Hydroxicarbamidum
Hydroxycarbamid
Hydroxycarbamide
Hydroxycarbamide (JAN/INN)
Hydroxycarbamidum
Hydroxycarbamidum [INN-Latin]
Hydroxycarbamine
Hydroxyharnstoff
Hydroxyharnstoff [German]
Hydroxylurea
Hydroxyurea
Hydroxyurea (D4)
Hydroxyurea (USP)
Hydroxyurea [USAN:BAN]
Hydroxyurea(d4)
 
Hydura
Hydurea
I05-0250
IDI1_000556
Idrossicarbamide
Idrossicarbamide [DCIT]
Idrossicarbamide [Dcit]
KBio1_000556
KBio2_001389
KBio2_003957
KBio2_006525
KBio3_001384
KBioGR_000383
KBioSS_001389
LS-709
Litaler
Litalir
Lopac-H-8627
Lopac0_000596
MLS001332381
MLS001332382
MLS002153389
MolMap_000029
MolPort-000-003-971
Mylocel
N-(Aminocarbonyl) Hydroxyamine
N-Carbamoylhydroxylamine
N-HYDROXY UREA
N-Hydroxymocovina
N-Hydroxymocovina [Czech]
N-Hydroxyurea
NCGC00015520-01
NCGC00015520-02
NCGC00015520-07
NCGC00093974-01
NCGC00093974-02
NCGC00093974-03
NCGC00093974-04
NCGC00093974-05
NCI C04831
NCI-C04831
NCI60_002773
NCIMech_000139
NHY
NINDS_000556
NSC 32065
NSC32065
Onco-Carbide
Onco-carbide
Oncocarbide
Oxyurea
S-phase/G-1 interface inhibitor
S1896_Selleck
SK 22591
SMR000059149
SPBio_000247
SPECTRUM1500344
SQ 1089
SQ-1089
Siklos
Spectrum2_000064
Spectrum3_000462
Spectrum4_000012
Spectrum5_000836
Spectrum_000909
Sterile Urea
TL8000673
UNII-X6Q56QN5QC
Ureaphil
WLN: ZVMQ
carbamide oxide
hydroxyaminomethanamide
hydroxyurea
nchembio.573-comp3
nchembio.90-comp4
nchembio749-comp3
tetratogen: inhibits ribonucleoside diphosphate reductase
13
Valproic Acidapproved, investigationalPhase 3, Phase 2, Phase 132799-66-13121
Synonyms:
(N-C3H7)2CHCOOH
(S)-2-propyl-4-pentanoate
(S)-2-propyl-4-pentanoic acid
2 PP (base)
2-N-Propyl-N-valeric acid
2-Propyl-Pentanoate
2-Propyl-Pentanoic acid
2-Propylpentanoate
2-Propylpentanoic Acid
2-Propylpentanoic acid
2-Propylvaleric Acid
2-Propylvaleric acid
2-n-Propyl-n-valeric acid
2-n-propyl-n-valeric acid
2-propyl-pentanoic acid
2-propylvaleric acid
4-Heptanecarboxylic acid
4-heptanecarboxylic acid
76584-70-8 (hydrochloride salt (2:1))
99-66-1
AC1L1F7T
AC1Q2ULA
AI3-10500
APO-divalproex
Abbott 44090
Acide valproique
Acide valproique [INN-French]
Acide valproique [inn-french]
Acido valproico
Acido valproico [INN-Spanish]
Acido valproico [inn-spanish]
Acidum valproicum
Acidum valproicum [INN-Latin]
Acidum valproicum [inn-latin]
Alti-Valproic
Alti-valproic
Apo-valproic
Apo-valproic syrup
Avugane
BIDD:GT0858
BRN 1750447
Baceca
C07185
CHEBI:39867
CHEMBL109
CID3121
CPD000499581
Convulex
Convulsofin
D00399
DB00313
DOM-divalproex
DOM-valproic
DOM-valproic acid E.C.
DPA
Delepsine
Depacon
Depakene
Depakene (TN)
Depakin
Depakin chrono
Depakine
Depakine chrono
Depakote
Depakote (TM)
Deproic
Di-N-propylacetic acid
Di-N-propylessigsaure
Di-N-propylessigsaure [german]
Di-n-propylacetic acid
Di-n-propylessigsaeure
Di-n-propylessigsaure
Di-n-propylessigsaure [German]
Di-n-propylessigsäure
Dipropyl Acetate
Dipropylacetate
Dipropylacetic acid
DivK1c_000273
Divalproex
Dom-Valproic
Dom-valproate
Dom-valproic acid
Dom-valproic acid syrup
EINECS 202-777-3
Epiject I.V.
Epilex
Epilim
Epival
Epival er
Ergenyl
G2M-777
Gen-divalproex
HMS2089J06
HSDB 3582
I04-0211
InChI=1/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10)
KBio1_000273
KBio2_001001
KBio2_002277
KBio2_003569
KBio2_004845
 
KBio2_006137
KBio2_007413
KBio3_002626
KBio3_002757
KBioGR_000871
KBioGR_002277
KBioSS_001001
KBioSS_002278
Kyselina 2-propylvalerova
Kyselina 2-propylvalerova [Czech]
LS-161170
LS-2068
MLS001076682
MLS001335927
MLS001335928
MLS002415770
Med Valproic
Med valproic
MolPort-001-791-895
Mylproin
Myproate
Myproic Acid
Myproic acid
N-DPA
N-Dipropylacetic acid
NCGC00091149-01
NCGC00091149-02
NCGC00091149-03
NCGC00091149-04
NINDS_000273
NSC 93819
NSC93819
Novo-Valproic
Novo-Valproic - ECC
Novo-divalproex
Novo-valproic
Novo-valproic soft gel cap
Nu-Valproic
Nu-valproic
P0823
P6273_SIGMA
PEAC
PHL-valproate
PHL-valproic acid
PHL-valproic acid E.C.
PMS-Divalproex
PMS-Valproic Acid
PMS-valproate
PMS-valproic acid
PMS-valproic acid E.C.
Penta-Valproic
Penta-valproic
Propylvaleric acid
Ratio-Valproic - ECC
S(-)-4-En-valproate
S(-)-4-En-valproic acid
S-2-N-Propyl-4-pentenoate
S-2-N-Propyl-4-pentenoic acid
SAM002564230
SBB065764
SMR000499581
SPBio_000912
Sandoz valproic
Savicol
Semisodium Valproate
Sodium hydrogen divalproate
Spectrum2_000946
Spectrum3_001733
Spectrum4_000376
Spectrum_000521
Sprinkle
Stavzor
UNII-614OI1Z5WI
VALPROIC ACID
VPA
Valcote
Valparin
Valproate
Valproate semisodique [French]
Valproate semisodium
Valproato semisodico [Spanish]
Valproatum seminatricum [Latin]
Valproic Acid, Sodium Salt (2:1)
Valproic acid
Valproic acid (USP)
Valproic acid USP
Valproic acid USP24
Valproic acid [USAN:INN:BAN]
Valproic acid [usan:ban:inn]
Valproinsaeure
Valproinsäure
Vupral
WLN: QVY3 & 3
acide valproïque
acidum valproicum
di-n-propylacetic acid
n-DPA
n-Dipropylacetic acid
nchembio.79-comp4
nchembio815-comp21
valproate
valproic acid
ácido valproico
14
4-AminopyridineapprovedPhase 2, Phase 369504-24-51727
Synonyms:
.gamma.-Aminopyridine
275875_ALDRICH
36687_FLUKA
36687_RIEDEL
4 AP
4 Aminopyridine
4 Aminopyridine Sustained Release
4-AP
4-Aminopyridine
4-Aminopyridine 10
4-Aminopyridine Sustained Release
4-Pyridinamine
4-Pyridylamine
4-aminopyridine
5-22-09-00106 (Beilstein Handbook Reference)
504-24-5
A 0152
A0414
A78403_ALDRICH
AB1004971
AC-907/25014071
AC1L1C3R
AC1Q52BM
AI3-52547
AKOS000119896
Amaya
Amino-4 pyridine
Amino-4-Pyridine
Ampydin
Ampyra
Avitrol
Avitrol 200
BB_SC-6974
BRN 0105782
BSPBio_001562
Bio1_000353
Bio1_000842
Bio1_001331
Bio2_000282
Bio2_000762
C13728
C5H6N2
CHEBI:34385
CHEMBL284348
CID1727
Caswell No. 038
Compound 1861
D015761
D04127
Dalfampridine
DivK1c_000572
EINECS 207-987-9
EL-970
EPA Pesticide Chemical Code 069201
EU-0100032
FT-0083754
Fampridina
Fampridine
Fampridine (USAN/INN)
Fampridine SR
Fampridine [USAN:INN]
Fampridine-PR
Fampridine-SR
Fampridinum
HC150041
HMS1361O04
HMS1791O04
HMS1921H15
HMS1989O04
HMS2092F05
HMS501M14
HSDB 6037
IDI1_000572
IDI1_034032
InChI=1/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7
KBio1_000572
 
KBio2_000282
KBio2_000635
KBio2_002850
KBio2_003203
KBio2_005418
KBio2_005771
KBio3_000563
KBio3_000564
KBio3_001888
KBioGR_000282
KBioGR_001505
KBioSS_000282
KBioSS_000635
LS-130202
Lopac-A-0152
Lopac0_000032
MLS000069400
Mi-W-3
MolPort-000-146-022
N07XX07
NCGC00015009-01
NCGC00015009-03
NCGC00015009-12
NCGC00024890-01
NCGC00024890-02
NCGC00024890-03
NCGC00024890-04
NCGC00024890-05
NCGC00024890-06
NCGC00024890-07
NCGC00024890-08
NCGC00024890-09
NCGC00024890-10
NINDS_000572
NSC 15041
NSC15041
Neurelan
Neurelan (TN)
P-Aminopyridine
PYRIDINE,4-AMINO
Philips 1861
Phillips 1861
Pimadin (free base)
Prc 1237
Pymadin
Pymadine
RCRA waste no. P008
SDCCGMLS-0066228.P001
SMR000058211
SPBio_001486
SPECTRUM1501130
STK298717
Spectrum2_001413
Spectrum3_000914
Spectrum4_001013
Spectrum5_001501
Spectrum_000155
Sustained Release, 4-Aminopyridine
TL8003344
Tocris-0940
UNII-BH3B64OKL9
UPCMLD-DP125
UPCMLD-DP125:001
VMI 10-3
VMI 103
VMI-10-3
VMI-103
VMI103
WLN: T6NJ DZ
[J.Pharmacol.Exp.Ther. 275:864 (1995)]
gamma-Aminopyridine
nchem.892-comp4
p-Aminopyridine
p-Aminopyridine [UN2671] [Poison]
p-Aminopyridine [UN2671] [Poison]
pyridin-4-amine
pyridin-4-ylamine
15
Riluzoleapproved, investigationalPhase 2, Phase 3651744-22-55070
Synonyms:
1744-22-5
2-Amino-6-(trifluoromethoxy)-benzothiazole
2-Amino-6-(trifluoromethoxy)benzothiazole
2-Amino-6-trifluoro- methoxybenzothiazole
2-amino-6-(trifluoromethoxy)-1,3-benzothiazole
2-amino-6-(trifluoromethoxy)benzo[d]thiazole
2-amino-6-(trifluoromethoxyl)benzothiazole
2-amino-6-trifluoromethoxybenzothiazole
6-(trifluoromethoxy)-1,3-benzothiazol-2-amine
6-(trifluoromethoxy)benzo[d]thiazol-2-amine
6-Trifluoromethoxy-benzothiazol-2-ylamine
6-trifluoromethoxybenzothiazole-2-yl-amine
AC-730
AC1L1JJL
AC1Q530H
AKOS000265071
ALBB-006046
Amino-2 trifluoromethoxy-6 benzothiazole
Amino-2 trifluoromethoxy-6 benzothiazole [French]
BB_SC-4839
BF-37
BIDD:GT0055
BPBio1_000037
BPBio1_000837
BRD-K21283037-001-02-5
BRD-K21283037-003-03-9
BSPBio_000033
Bio1_000416
Bio1_000905
Bio1_001394
Biomol-NT_000245
C07937
C8H5F3N2OS
CHEMBL744
CID5070
D00775
DB00740
EU-0101064
FT-0082997
HMS1773G08
HMS2089O19
HMS2094G07
I01-2084
LS-40688
 
Lopac-R-116
Lopac0_001064
MLS000069369
MolPort-000-151-262
NCGC00015882-01
NCGC00015882-02
NCGC00015882-03
NCGC00015882-07
NCGC00015882-11
NCGC00023141-02
NCGC00023141-04
NCGC00023141-05
NCGC00023141-06
PK-26124
PK-26124, RP-54274, Rilutek, Riluzole
Prestwick-03A08
Prestwick0_000167
Prestwick1_000167
Prestwick2_000167
Prestwick3_000167
R-116
R116_SIGMA
RP 54274
RP-54274
Rilutek
Rilutek (TN)
Riluzol
Riluzol [INN-Spanish]
Riluzole
Riluzole (JAN/USAN/INN)
Riluzole HCl
Riluzole [USAN:INN]
Riluzolum
Riluzolum [INN-Latin]
S1614_Selleck
SMR000058231
SPBio_000599
SPBio_001954
STK503686
Spectrum2_000550
Tocris-0768
UNII-7LJ087RS6F
ZERO/001785
ZINC00006481
riluzole
16Nucleic Acid Synthesis InhibitorsPhase 2, Phase 3, Phase 14962
17Antimanic AgentsPhase 3, Phase 2, Phase 1814
18Central Nervous System DepressantsPhase 3, Phase 2, Phase 113403
19Psychotropic DrugsPhase 3, Phase 2, Phase 16430
20Tranquilizing AgentsPhase 3, Phase 2, Phase 14265
21GABA AgentsPhase 3, Phase 2, Phase 11684
22Excitatory Amino Acid AntagonistsPhase 2, Phase 31347
23Excitatory Amino AcidsPhase 2, Phase 31362
24AnticonvulsantsPhase 2, Phase 3, Phase 12695
25Potassium Channel BlockersPhase 2, Phase 3180
26Neurotransmitter AgentsPhase 2, Phase 3, Phase 118340
27Neuroprotective AgentsPhase 2, Phase 31716
28Protective AgentsPhase 2, Phase 37443
29Omega 3 Fatty AcidNutraceuticalPhase 31018
30carnitineNutraceuticalPhase 3, Phase 2, Phase 1162
31FlaxNutraceuticalPhase 398
32PiracetamapprovedPhase 21757491-74-9
33
Leuprolideapproved, investigationalPhase 229953714-56-03911, 657181
Synonyms:
(D-Leu(6),des-gly-NH2(10),pro-ethylamide(9))-gonadotropin-releasing hormone
5-oxoPro-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-ProNHC2H5 dihydrate
5-oxoprolylhistidyltryptophylseryltyrosylleucylleucyl-n5-(diaminomethylidene)ornithyl-n-ethylprolinamide
AC1L1GZK
AC1L9B44
AC1Q5OPO
AR-1G9354
C07612
CID3911
CID441410
D00989
D08113
Enantone
Enantone (TN)
I04-0109
L-Pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-L-proline ethylamide
L001094
 
L002030
Leuprolide
Leuprolide acetate
Leuprolide acetate (USAN)
Leuprorelin
Leuprorelin (INN)
Leuprorelin acetate (JAN)
Leuprorelina
Leuproreline
Leuprorelinum
Lupron (TN)
N-[1-[[1-[[1-[[1-[[1-[[1-[[5-(diaminomethylideneamino)-1-[2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
NSC377526
NSC746847
PGlu-his-trp-ser-tyr-D-leu-leu-arg-pro-NHC2H5
PGlu-his-trp-ser-tyr-D-leu-leu-arg-pro-nhet
acetic acid
leuprolide
34
Celecoxibapproved, investigationalPhase 2444169590-42-52662
Synonyms:
169590-42-5
184007-95-2
1oq5
4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide
4-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE
4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1Hpyrazol-1-yl] benzenesulfonamide
4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
AC-4228
AC1L1E6K
AI-525
BIDD:GT0408
BRD-K02637541-001-02-4
BSPBio_003596
Benzenesulfonamide,4-(5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)
C07589
C105934
C17H14F3N3O2S
CCRIS 8679
CEL
CEP-33222
CHEBI:41423
CHEMBL118
CID2662
CPD000550473
Celebra
Celebrex
Celebrex (TN)
Celebrex, Celebra, Celecoxib
Celecox
Celecoxi
Celecoxib
Celecoxib (JAN/USAN/INN)
Celecoxib (SC-58635)
Celecoxib [Old RN]
Celecoxib [USAN]
Celecoxibum
Celocoxib
Célécoxib
D00567
DB00482
DivK1c_000893
Eurocox
FT-0080064
HMS1922G14
HMS2089L18
HMS2093I07
HMS502M15
HSDB 7038
I01-1033
IDI1_000893
KBio1_000893
KBio2_000912
 
KBio2_002351
KBio2_003480
KBio2_004919
KBio2_006048
KBio2_007487
KBio3_002830
KBio3_003037
KBioGR_000723
KBioGR_002351
KBioSS_000912
KBioSS_002354
LS-31667
MLS001165684
MLS001195656
MLS001304708
Medicoxib
MolPort-002-885-815
NCGC00091455-01
NCGC00091455-02
NCGC00091455-03
NCGC00091455-04
NCI60_041049
NINDS_000893
NSC719627
Onsenal
P-(5-P-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide
Pfizer brand of celecoxib
S1261_Selleck
SAM002589995
SC 58635
SC-58553, SC-58635
SC-58635
SC58635
SMR000550473
SPBio_001512
SPECTRUM1503678
Solexa
Spectrum2_001576
Spectrum3_001996
Spectrum4_000182
Spectrum5_001324
Spectrum_000432
TL8001323
TPI-336
UNM-0000305813
Xilebao
YM 177
YM-177
YM177
ZINC02570895
cMAP_000027
celecoxib
p-(5-p-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide
35Antirheumatic AgentsPhase 210956
36Interleukin 1 Receptor Antagonist ProteinPhase 299
37Pharmaceutical SolutionsPhase 2, Phase 1, Early Phase 18192
38Nootropic AgentsPhase 2716
39AnalgesicsPhase 211733
40Analgesics, Non-NarcoticPhase 26501
41EtiracetamPhase 2207
42Fertility AgentsPhase 2505
43Peripheral Nervous System AgentsPhase 2, Early Phase 123689
444-phenylbutyric acidPhase 1, Phase 248
45Cholinesterase InhibitorsPhase 2592
46BromidesPhase 2642
47Cholinergic AgentsPhase 23992
48Pyridostigmine BromidePhase 227101-26-8
49Cyclooxygenase 2 InhibitorsPhase 2624
50Cyclooxygenase InhibitorsPhase 22870

Interventional clinical trials:

(show top 50)    (show all 172)
idNameStatusNCT IDPhase
1Physiologic Effects of PRMS & Testosterone in the Debilitated ElderlyCompletedNCT00018356Phase 4
2A Study to Assess the Efficacy and Safety of Nusinersen (ISIS 396443) in Participants With Later-onset Spinal Muscular Atrophy (SMA)CompletedNCT02292537Phase 3
3A Trial of Hydroxyurea in Spinal Muscular AtrophyCompletedNCT00485511Phase 2, Phase 3
4A Study to Assess the Efficacy and Safety of Nusinersen (ISIS 396443) in Infants With Spinal Muscular AtrophyCompletedNCT02193074Phase 3
5Short and Long Term Treatment With 4-AP in Ambulatory SMA PatientsCompletedNCT01645787Phase 2, Phase 3
6Study to Evaluate the Efficacy of Riluzole in Children and Young Adults With Spinal Muscular Atrophy (SMA)CompletedNCT00774423Phase 2, Phase 3
7The Combined Effects of Resistance Training and Flax Oil Supplementation Upon Inflammation in Older AdultsCompletedNCT00465153Phase 3
8Valproate and Levocarnitine in Children With Spinal Muscular AtrophyRecruitingNCT01671384Phase 3
9A Study for Participants With Spinal Muscular Atrophy (SMA) Who Previously Participated in Nusinersen (ISIS 396443) Investigational Studies.Enrolling by invitationNCT02594124Phase 3
10Combining Testosterone Therapy and Exercise to Improve Function Post Hip FractureNot yet recruitingNCT02938923Phase 3
11A Pilot Therapeutic Trial Using Hydroxyurea in Type II and Type III Spinal Muscular Atrophy PatientsUnknown statusNCT00568802Phase 1, Phase 2
12Safety and Tolerability of Anakinra in Combination With Riluzol in Amyotrophic Lateral SclerosisUnknown statusNCT01277315Phase 2
13Transcranial Direct Current Stimulation as a Novel Therapeutic Approach in Amyotrophic Lateral SclerosisUnknown statusNCT01569958Phase 2
14Ghrelin Plus Strength Training in Frail Elderly StudyUnknown statusNCT01898611Phase 2
15Efficacy of Umbilical Cord Mesenchymal Stem Cells in Duchenne Muscular DystrophyUnknown statusNCT02285673Phase 1, Phase 2
16Valproic Acid and Carnitine in Patients With Spinal Muscular AtrophyCompletedNCT00227266Phase 2
17Valproic Acid in Ambulant Adults With Spinal Muscular AtrophyCompletedNCT00481013Phase 2
18Study to Evaluate Sodium Phenylbutyrate in Pre-symptomatic Infants With Spinal Muscular AtrophyCompletedNCT00528268Phase 1, Phase 2
19CARNIVAL Type I: Valproic Acid and Carnitine in Infants With Spinal Muscular Atrophy (SMA) Type ICompletedNCT00661453Phase 1, Phase 2
20An Open-label Safety, Tolerability and Dose-Range Finding Study of Multiple Doses of Nusinersen (ISIS 396443) in Participants With Spinal Muscular AtrophyCompletedNCT01703988Phase 1, Phase 2
21A Pilot Therapeutic Trial Using Hydroxyurea in Type I Spinal Muscular Atrophy PatientsCompletedNCT00568698Phase 1, Phase 2
22Safety and Efficacy of Olesoxime (TRO19622) in 3-25 Years SMA Patients.CompletedNCT01302600Phase 2
23Pilot Study of Growth Hormon to Treat SMA Typ II and IIICompletedNCT00533221Phase 2
24Levetiracetam for Cramps, Spasticity and Neuroprotection in Motor Neuron DiseaseCompletedNCT00324454Phase 2
25Phase II Study of Leuprolide and Testosterone for Men With Kennedy's Disease or Other Motor Neuron DiseaseCompletedNCT00004771Phase 2
26Effects of Power Mobility on Young Children With Severe Motor ImpairmentsCompletedNCT01028833Phase 2
27Investigating Modes of Progressive MobilityCompletedNCT00787098Phase 2
28Effect of Functional Exercise in Patients With Spinal Bulbar Muscular AtrophyCompletedNCT01369901Phase 1, Phase 2
29Musculoskeletal Effects of BicarbonateCompletedNCT01475214Phase 2
30Treatment of Dysphagia in Oculopharyngeal Muscular Dystrophy by Autologous Transplantation of MyoblastsCompletedNCT00773227Phase 2
31A Phase 2 Study to Evaluate the Dose and Pharmacodynamic Efficacy of Sialic Acid-Extended Release (SA-ER) Tablets in Patients With GNE Myopathy or Hereditary Inclusion Body MyopathyCompletedNCT01517880Phase 2
32A Study of CK-2127107 in Patients With Spinal Muscular AtrophyRecruitingNCT02644668Phase 2
33A Study of RO7034067 in Adult and Pediatric Participants With Spinal Muscular AtrophyRecruitingNCT03032172Phase 2
34Safety and Efficacy Study of Pyridostigmine on Patients With Spinal Muscular Atrophy Type 3RecruitingNCT02227823Phase 2
35A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of RO7034067 in Infants With Type1 Spinal Muscular Atrophy (Firefish)RecruitingNCT02913482Phase 2
36A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of RO7034067 in Type 2 and 3 Spinal Muscular Atrophy Participants (Sunfish)RecruitingNCT02908685Phase 2
37SPACE Trial: Pyridostigmine vs Placebo in SMA Types 2, 3 and 4RecruitingNCT02941328Phase 2
38Allogeneic Adipose Derived Stem Cells for Werdnig Hoffman PatientsRecruitingNCT02855112Phase 1, Phase 2
39Use of (-)-Epicatechin in the Treatment of Becker Muscular Dystrophy (Pilot Study)RecruitingNCT01856868Phase 1, Phase 2
40Task-oriented Upper Limb Training in MSRecruitingNCT02688231Phase 2
41An Open Label Study of LMI070 in Type 1 Spinal Muscular Atrophy (SMA)Active, not recruitingNCT02268552Phase 1, Phase 2
42A Study to Assess the Efficacy, Safety and Pharmacokinetics of Nusinersen (ISIS 396443) in Infants With Spinal Muscular Atrophy (SMA)Active, not recruitingNCT01839656Phase 2
43A Study of Multiple Doses of Nusinersen (ISIS 396443) Delivered to Infants With Genetically Diagnosed and Presymptomatic Spinal Muscular AtrophyActive, not recruitingNCT02386553Phase 2
44A Study to Assess the Safety and Tolerability of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA).Active, not recruitingNCT02462759Phase 2
45A Study to Evaluate Long Term Safety, Tolerability, and Effectiveness of Olesoxime in Participants With Spinal Muscular Atrophy (SMA)Active, not recruitingNCT02628743Phase 2
46Autologous Bone Marrow-Derived Stem Cell Therapy for Motor Neuron DiseaseActive, not recruitingNCT03067857Phase 1, Phase 2
47Effect of Low-Dose Celecoxib on SMN2 in Patients With Spinal Muscular AtrophyNot yet recruitingNCT02876094Phase 2
48Postacute Sarcopenia: Supplementation With β-hydroxyMethylbutyrate After Resistance TrainingNot yet recruitingNCT02679742Phase 2
49Clinical Trial of Sodium Phenylbutyrate in Children With Spinal Muscular Atrophy Type ITerminatedNCT00439218Phase 1, Phase 2
50Clinical Trial of Sodium Phenylbutyrate in Children With Spinal Muscular Atrophy Types II or IIITerminatedNCT00439569Phase 1, Phase 2

Search NIH Clinical Center for Progressive Muscular Atrophy

Genetic Tests for Progressive Muscular Atrophy

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Anatomical Context for Progressive Muscular Atrophy

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MalaCards organs/tissues related to Progressive Muscular Atrophy:

36
Spinal cord, Brain

Publications for Progressive Muscular Atrophy

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Articles related to Progressive Muscular Atrophy:

(show top 50)    (show all 89)
idTitleAuthorsYear
1
Unilateral progressive muscular atrophy with fast symptoms progression. (26851691)
2016
2
Association of IgM monoclonal gammopathy with progressive muscular atrophy and multifocal motor neuropathy: a case-control study. (25549972)
2015
3
CSF cytokine profile distinguishes multifocal motor neuropathy from progressive muscular atrophy. (26280014)
2015
4
The diagnostic dilemma of progressive muscular atrophy. (25703763)
2015
5
Cytokine profiles in multifocal motor neuropathy and progressive muscular atrophy. (26298317)
2015
6
Progressive Muscular Atrophy. (26515620)
2015
7
Neuropsychological investigation in Chinese patients with progressive muscular atrophy. (26042930)
2015
8
Progressive muscular atrophy: A patient with confirmatory postmortem findings. (25598220)
2015
9
Acute intermittent porphyria presenting as progressive muscular atrophy in a young black man. (25118551)
2014
10
Prefrontal involvement related to cognitive impairment in progressive muscular atrophy. (25080518)
2014
11
Differential motor neuron involvement in progressive muscular atrophy: a comparative study with amyotrophic lateral sclerosis. (24833696)
2014
12
SMN1 gene duplications are more frequent in patients with progressive muscular atrophy. (23477310)
2013
13
Klinefelter's syndrome associated with progressive muscular atrophy simulating Kennedy's disease. (22919202)
2012
14
Mutations in the TRPV4 gene are not associated with sporadic progressive muscular atrophy. (22689196)
2012
15
Cognitive dysfunction in lower motor neuron disease: executive and memory deficits in progressive muscular atrophy. (20562407)
2011
16
Study of 962 patients indicates progressive muscular atrophy is a form of ALS. (20530332)
2010
17
Motor neuron disease: progressive muscular atrophy in the ALS spectrum. (20379201)
2010
18
Progressive muscular atrophy and other lower motor neuron syndromes of adults. (20082312)
2010
19
Study of 962 patients indicates progressive muscular atrophy is a form of ALS. (20530331)
2010
20
Study of 962 patients indicates progressive muscular atrophy is a form of ALS. (19917992)
2009
21
Interpretation of electrodiagnostic findings in sporadic progressive muscular atrophy. (18484238)
2008
22
The history of progressive muscular atrophy: syndrome or disease? (18299524)
2008
23
Clinical patterns in progressive muscular atrophy (PMA): a prospective study. (17852011)
2007
24
Disease course and prognostic factors of progressive muscular atrophy. (17420313)
2007
25
Anti-Ma2 associated paraneoplastic neurological syndrome presenting as encephalitis and progressive muscular atrophy. (16361608)
2006
26
Absence of cognitive, behavioral, or emotional dysfunction in progressive muscular atrophy. (17101922)
2006
27
Diffusion-tensor MR imaging of corticospinal tract in amyotrophic lateral sclerosis and progressive muscular atrophy. (16183935)
2005
28
Myasthenia gravis with anti-MuSK antibody, showing progressive muscular atrophy without blepharoptosis. (16020904)
2005
29
Proximal myotonic dystrophy mimicking progressive muscular atrophy. (15679706)
2005
30
Sporadic amyotrophic lateral sclerosis of long duration mimicking spinal progressive muscular atrophy exists: additional autopsy case with a clinical course of 19 years. (15484701)
2004
31
Abrupt onset of progressive muscular atrophy. (15204026)
2004
32
Corticospinal tract degeneration in the progressive muscular atrophy variant of ALS. (12707426)
2003
33
Mitral valve surgery in a patient with spinal progressive muscular atrophy: report of a case. (14506997)
2003
34
A novel missense mutation of AIRE gene in a patient with autoimmune polyendocrinopathy, candidiasis and ectodermal dystrophy (APECED), accompanied with progressive muscular atrophy: case report and review of the literature in Japan. (12625412)
2002
35
Progressive muscular atrophy variant of familial amyotrophic lateral sclerosis (PMA/ALS). (10980308)
2000
36
Sporadic amyotrophic lateral sclerosis of long duration mimicking spinal progressive muscular atrophy: a clinicopathological study. (10202983)
1999
37
Cortical function in progressive muscular atrophy and amyotrophic lateral sclerosis. (7807149)
1994
38
Nemaline bodies in spinal progressive muscular atrophy. An autopsy case. (2821729)
1987
39
A survival analysis of 155 cases of progressive muscular atrophy. (4082906)
1985
40
Progressive muscular atrophy and posterior dislocation of the humerus following electric shock. (6709547)
1984
41
Late progressive muscular atrophy and antecedent poliomyelitis. (6983825)
1982
42
Adult GM2 gangliosidosis masquerading as slowly progressive muscular atrophy: motor neuron disease phenotype. (7166018)
1982
43
CSF viral antibodies. Evaluation in amyotrophic lateral sclerosis and late-onset postpoliomyelitis progressive muscular atrophy. (220938)
1979
44
Hereditary myoclonus and progressive muscular atrophy: a new syndrome. (757033)
1978
45
A modern method of the spectral analysis of the electromyogram in the spinal progressive muscular atrophy. (802629)
1976
46
The case of the saltimbanque Prosper Lecomte. A contribution to the study of the history of progressive muscular atrophy (Aran-Duchenne) and amyotrophic lateral sclerosis (Charcot). (782762)
1975
47
Werdnig-Hoffman's disease--infantile progressive muscular atrophy report of case. (1089112)
1975
48
A case of spinal progressive muscular atrophy of lumbosacral leg thigh type. (5562105)
1971
49
Two early infantile hereditary cases of progressive muscular atrophy simulating dystrophy, but on a neural basis. 1891. (4952838)
1971
50
Electromyographic analysis in spinal progressive muscular atrophy, juvenile unilateral muscular atrophy, neural progressive muscular atrophy and myeloradiculoneuritis. (5984523)
1966

Variations for Progressive Muscular Atrophy

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Expression for genes affiliated with Progressive Muscular Atrophy

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Search GEO for disease gene expression data for Progressive Muscular Atrophy.

Pathways for genes affiliated with Progressive Muscular Atrophy

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GO Terms for genes affiliated with Progressive Muscular Atrophy

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Cellular components related to Progressive Muscular Atrophy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1Cajal bodyGO:001503010.3SMN1, SMN2
2cytoplasmic ribonucleoprotein granuleGO:003646410.3SMN1, SMN2
3Gemini of coiled bodiesGO:009750410.3SMN1, SMN2
4SMN complexGO:003279710.3SMN1, SMN2
5SMN-Sm protein complexGO:003471910.3SMN1, SMN2
6Z discGO:00300189.2CAV3, SMN1, SMN2

Biological processes related to Progressive Muscular Atrophy according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1DNA-templated transcription, terminationGO:000635310.4SMN1, SMN2
2nuclear importGO:005117010.4SMN1, SMN2
3actin filament organizationGO:000701510.2CAV3, TRPV4
4spliceosomal complex assemblyGO:000024510.1SMN1, SMN2
5mRNA processingGO:00063979.8SMN1, SMN2, TARDBP
6spliceosomal snRNP assemblyGO:00003879.8SMN1, SMN2
7RNA splicingGO:00083809.6SMN1, SMN2, TARDBP

Molecular functions related to Progressive Muscular Atrophy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1alpha-tubulin bindingGO:004301410.2CAV3, TRPV4
2identical protein bindingGO:00428028.7AIRE, SMN1, SMN2, TARDBP

Sources for Progressive Muscular Atrophy

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2CDC
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