PTGC
MCID: PRG036
MIFTS: 12

Progressive Transformation of Germinal Centers (PTGC) malady

Categories: Rare diseases

Aliases & Classifications for Progressive Transformation of Germinal Centers

Aliases & Descriptions for Progressive Transformation of Germinal Centers:

Name: Progressive Transformation of Germinal Centers 50
Ptgc 50

Classifications:



Summaries for Progressive Transformation of Germinal Centers

NIH Rare Diseases : 50 progressive transformation of germinal centers is a condition in which a lymph node becomes very enlarged (lymphadenopathy).  typically, only one lymph node is affected, though ptgc can involve multiple lymph nodes.  the neck is the most common location of affected lymph nodes, but ptgc may also affect lymph nodes in the groin and armpits.  adults are more frequently affected than children, but children have a higher chance of developing ptgc multiple times (recurrence).  ptgc is not considered a precancerous condition, though it has been associated with hodgkin lymphoma. last updated: 4/24/2013

MalaCards based summary : Progressive Transformation of Germinal Centers, also known as ptgc, is related to lymphoma and hodgkin lymphoma. Affiliated tissues include lymph node and thyroid.

Related Diseases for Progressive Transformation of Germinal Centers

Diseases related to Progressive Transformation of Germinal Centers via text searches within MalaCards or GeneCards Suite gene sharing:

id Related Disease Score Top Affiliating Genes
1 lymphoma 10.2
2 hodgkin lymphoma 10.1
3 follicular lymphoma 10.0
4 thyroid cancer 9.8
5 cervicitis 9.8
6 thyroiditis 9.8
7 nodular lymphocyte predominant hodgkin lymphoma 9.8

Graphical network of the top 20 diseases related to Progressive Transformation of Germinal Centers:



Diseases related to Progressive Transformation of Germinal Centers

Symptoms & Phenotypes for Progressive Transformation of Germinal Centers

Drugs & Therapeutics for Progressive Transformation of Germinal Centers

Search Clinical Trials , NIH Clinical Center for Progressive Transformation of Germinal Centers

Genetic Tests for Progressive Transformation of Germinal Centers

Anatomical Context for Progressive Transformation of Germinal Centers

MalaCards organs/tissues related to Progressive Transformation of Germinal Centers:

39
Lymph Node, Thyroid

Publications for Progressive Transformation of Germinal Centers

Articles related to Progressive Transformation of Germinal Centers:

(show all 25)
id Title Authors Year
1
Progressive Transformation of Germinal Centers: Single-Center Experience of 33 Turkish Patients. ( 27133958 )
2016
2
Papillary Thyroid Cancer in a Child with Progressive Transformation of Germinal Centers. ( 27069706 )
2016
3
Immunoarchitectural patterns of progressive transformation of germinal centers with and without nodular lymphocyte-predominant Hodgkin lymphoma. ( 26410017 )
2015
4
A pediatric translational perspective on the entity "progressive transformation of germinal centers (PTGC)". ( 22976884 )
2013
5
Progressive transformation of germinal centers in children and adolescents: an intriguing cause of lymphadenopathy. ( 22707034 )
2013
6
Progressive transformation of germinal centers and Hodgkin lymphoma: more insights but maybe more confusion? ( 21888616 )
2011
7
Efficacy and safety of rituximab treatment in patients with progressive transformation of germinal centers after Hodgkin lymphoma in complete remission post-induction chemotherapy and radiotherapy. ( 21663508 )
2011
8
In situ follicular lymphoma associated with progressive transformation of germinal centers. ( 19948639 )
2011
9
Progressive transformation of germinal centers in a pediatric patient: initial evaluation and follow-up with serial F-18 FDG PET/CT imaging. ( 21892026 )
2011
10
Progressive transformation of germinal centers (PTGC) in the head and neck. ( 21225766 )
2010
11
PET positive progressive transformation of germinal centers masquerading as relapsed Hodgkin lymphoma post-autograft. ( 16886280 )
2006
12
Progressive transformation of germinal centers: an uncommon cause of pediatric cervical lymphadenopathy. ( 16847193 )
2006
13
Progressive transformation of germinal center presenting with histological features of hyaline-vascular type of Castleman's disease. ( 15865611 )
2005
14
Progressive transformation of germinal centers: a clinicopathological study of 42 Japanese patients. ( 12754626 )
2003
15
Follicular hyperplasia, follicular lysis, and progressive transformation of germinal centers. A sequential spectrum of morphologic evolution in lymphoid hyperplasia. ( 14502795 )
2003
16
Progressive transformation of germinal centers. Report of 2 cases and review of the literature. ( 12145465 )
2002
17
Progressive transformation of germinal centers: review of histopathologic and clinical features. ( 12242134 )
2002
18
Progressive transformation of germinal centers and nodular lymphocyte predominance Hodgkin's disease: a comparative immunohistochemical study. ( 9888701 )
1999
19
Florid progressive transformation of germinal centers. A syndrome affecting young men, without early progression to nodular lymphocyte predominance Hodgkin's disease. ( 1599017 )
1992
20
Progressive transformation of germinal centers: comparison of 23 pediatric patients to the adult population. ( 1574490 )
1992
21
Progressive transformation of germinal centers with and without association to Hodgkin's disease. ( 2405631 )
1990
22
Follicular lymphoma mimicking progressive transformation of germinal centers: immunologic analysis of a case. ( 3052020 )
1988
23
Follicular lymphoma mimicking progressive transformation of germinal centers. ( 3307374 )
1987
24
Clinical implications of progressive transformation of germinal centers. ( 6496841 )
1984
25
Differential diagnostic features of nodular L & H Hodgkin's disease, including progressive transformation of germinal centers. ( 6369997 )
1984

Variations for Progressive Transformation of Germinal Centers

Expression for Progressive Transformation of Germinal Centers

Search GEO for disease gene expression data for Progressive Transformation of Germinal Centers.

Pathways for Progressive Transformation of Germinal Centers

GO Terms for Progressive Transformation of Germinal Centers

Sources for Progressive Transformation of Germinal Centers

3 CDC
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48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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