MCID: PRG036
MIFTS: 11

Progressive Transformation of Germinal Centers malady

Rare diseases category

Aliases & Classifications for Progressive Transformation of Germinal Centers

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Progressive Transformation of Germinal Centers, Aliases & Descriptions:

Name: Progressive Transformation of Germinal Centers 41
 
Ptgc 41


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


Summaries for Progressive Transformation of Germinal Centers

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NIH Rare Diseases:41 Progressive transformation of germinal centers is a condition in which a lymph node becomes very enlarged (lymphadenopathy).  typically, only one lymph node is affected, though ptgc can involve multiple lymph nodes.  the neck is the most common location of affected lymph nodes, but ptgc may also affect lymph nodes in the groin and armpits.  adults are more frequently affected than children, but children have a higher chance of developing ptgc multiple times (recurrence).  ptgc is not considered a precancerous condition, though it has been associated with hodgkin lymphoma. last updated: 4/24/2013

MalaCards based summary: Progressive Transformation of Germinal Centers, also known as ptgc, is related to hodgkin lymphoma and follicular lymphoma. Affiliated tissues include lymph node.

Related Diseases for Progressive Transformation of Germinal Centers

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Diseases related to Progressive Transformation of Germinal Centers via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1hodgkin lymphoma10.6
2follicular lymphoma10.5
3cervicitis10.3
4castleman's disease10.3

Symptoms for Progressive Transformation of Germinal Centers

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Drugs & Therapeutics for Progressive Transformation of Germinal Centers

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Drug clinical trials:

Search ClinicalTrials for Progressive Transformation of Germinal Centers

Search NIH Clinical Center for Progressive Transformation of Germinal Centers

Genetic Tests for Progressive Transformation of Germinal Centers

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Anatomical Context for Progressive Transformation of Germinal Centers

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MalaCards organs/tissues related to Progressive Transformation of Germinal Centers:

31
Lymph node

Animal Models for Progressive Transformation of Germinal Centers or affiliated genes

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Publications for Progressive Transformation of Germinal Centers

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Articles related to Progressive Transformation of Germinal Centers:

(show all 21)
idTitleAuthorsYear
1
Progressive transformation of germinal centers in children and adolescents: an intriguing cause of lymphadenopathy. (22707034)
2013
2
A pediatric translational perspective on the entity "progressive transformation of germinal centers (PTGC)". (22976884)
2013
3
Progressive transformation of germinal centers and Hodgkin lymphoma: more insights but maybe more confusion? (21888616)
2011
4
Efficacy and safety of rituximab treatment in patients with progressive transformation of germinal centers after Hodgkin lymphoma in complete remission post-induction chemotherapy and radiotherapy. (21663508)
2011
5
Progressive transformation of germinal centers in a pediatric patient: initial evaluation and follow-up with serial F-18 FDG PET/CT imaging. (21892026)
2011
6
Progressive transformation of germinal centers (PTGC) in the head and neck. (21225766)
2010
7
PET positive progressive transformation of germinal centers masquerading as relapsed Hodgkin lymphoma post-autograft. (16886280)
2006
8
Progressive transformation of germinal centers: an uncommon cause of pediatric cervical lymphadenopathy. (16847193)
2006
9
Progressive transformation of germinal center presenting with histological features of hyaline-vascular type of Castleman's disease. (15865611)
2005
10
Progressive transformation of germinal centers: a clinicopathological study of 42 Japanese patients. (12754626)
2003
11
Follicular hyperplasia, follicular lysis, and progressive transformation of germinal centers. A sequential spectrum of morphologic evolution in lymphoid hyperplasia. (14502795)
2003
12
Progressive transformation of germinal centers. Report of 2 cases and review of the literature. (12145465)
2002
13
Progressive transformation of germinal centers: review of histopathologic and clinical features. (12242134)
2002
14
Progressive transformation of germinal centers and nodular lymphocyte predominance Hodgkin's disease: a comparative immunohistochemical study. (9888701)
1999
15
Florid progressive transformation of germinal centers. A syndrome affecting young men, without early progression to nodular lymphocyte predominance Hodgkin's disease. (1599017)
1992
16
Progressive transformation of germinal centers: comparison of 23 pediatric patients to the adult population. (1574490)
1992
17
Progressive transformation of germinal centers with and without association to Hodgkin's disease. (2405631)
1990
18
Follicular lymphoma mimicking progressive transformation of germinal centers: immunologic analysis of a case. (3052020)
1988
19
Follicular lymphoma mimicking progressive transformation of germinal centers. (3307374)
1987
20
Differential diagnostic features of nodular L & H Hodgkin's disease, including progressive transformation of germinal centers. (6369997)
1984
21
Clinical implications of progressive transformation of germinal centers. (6496841)
1984

Variations for Progressive Transformation of Germinal Centers

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Expression for genes affiliated with Progressive Transformation of Germinal Centers

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Search GEO for disease gene expression data for Progressive Transformation of Germinal Centers.

Pathways for genes affiliated with Progressive Transformation of Germinal Centers

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Compounds for genes affiliated with Progressive Transformation of Germinal Centers

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GO Terms for genes affiliated with Progressive Transformation of Germinal Centers

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Products for genes affiliated with Progressive Transformation of Germinal Centers

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Progressive Transformation of Germinal Centers

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet