MCID: PRL009
MIFTS: 63

Prolactinoma malady

Categories: Genetic diseases, Rare diseases, Reproductive diseases, Endocrine diseases, Cancer diseases

Aliases & Classifications for Prolactinoma

About this section
Sources:
11Disease Ontology, 13DISEASES, 52Orphanet, 48Novoseek, 37MeSH, 66UMLS, 46NIH Rare Diseases, 25GTR, 43NCIt, 29ICD10 via Orphanet, 38MESH via Orphanet, 67UMLS via Orphanet, 60SNOMED-CT
See all MalaCards sources

Aliases & Descriptions for Prolactinoma:

Name: Prolactinoma 11 13 52 48 37 66
Prolactinoma, Familial 46 25
Pituitary Adenoma, Prolactin-Secreting 11
Prolactin-Secreting Pituitary Adenoma 52
Prl-Secreting Pituitary Adenoma 52
 
Prolactinoma of Pituitary Gland 11
Pituitary Lactotrophic Adenoma 52
Familial Prolactinoma 11
Lactotroph Adenoma 52
Prloma 52

Characteristics:

Orphanet epidemiological data:

52
prolactinoma:
Inheritance: Not applicable; Prevalence: 1-5/10000 (United Kingdom),6-9/10000 (Belgium),1-5/10000 (Switzerland),1-9/100000 (Malta); Age of onset: Adolescent,Adult,Childhood,Elderly; Age of death: normal life expectancy

Classifications:



External Ids:

Disease Ontology11 DOID:5394
MeSH37 D015175
NCIt43 C3342
Orphanet52 ORPHA2965
ICD10 via Orphanet29 D35.2, E22.1
MESH via Orphanet38 D015175
UMLS via Orphanet67 C0033375

Summaries for Prolactinoma

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NIH Rare Diseases:46 A prolactinoma is a tumor of the pituitary gland, which controls production of many hormones.  a prolactinoma causes increased levels of the hormone prolactin.  the symptoms of prolactinoma may include unusual milk production (galactorrhea) or no menstrual cycles (amenorrhea) in women or decreased sex drive in men.  most prolactinomas occur by chance (sporadically); in a small number of cases, prolactinoma may be associated with an inherited condition such as multiple endocrine neoplasia type 1 (men1) or other genetic factors. last updated: 4/5/2015

MalaCards based summary: Prolactinoma, also known as prolactinoma, familial, is related to pituitary adenoma, prolactin-secreting and diabetes insipidus, and has symptoms including Array, Array and Array. An important gene associated with Prolactinoma is MEN1 (Menin 1), and among its related pathways are Nongenotropic Androgen signaling and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include pituitary, bone and thyroid, and related mouse phenotypes are adipose tissue and limbs/digits/tail.

Wikipedia:69 A prolactinoma is a benign tumor (adenoma) of the pituitary gland that produces a hormone called... more...

Related Diseases for Prolactinoma

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Diseases related to Prolactinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 192)
idRelated DiseaseScoreTop Affiliating Genes
1pituitary adenoma, prolactin-secreting31.8AIP, IGF1, PRL, SST, SSTR5
2diabetes insipidus30.0GNRH1, IGF1, PRL
3leukemia30.0BMP4, IGF1, TGFB1
4lateral sclerosis29.5ESR1, GNRH1, PRL, SHBG
5gastrinoma29.3SST, VIP
6prolactin producing pituitary tumor24.1AIP, BMP4, DRD2, ESR1, FGF2, GNRH1
7prolactinoma10.7IGF1, SST
8ovarian mucinous malignant adenofibroma10.7PRL, SST
9hyperprolactinemia10.7
10pearson syndrome10.7MEN1, SST
11isolated levocardia10.7MEN1, SST
12erysipelas10.6DRD2, PRL
13benign prostate phyllodes tumor10.6GNRH1, PRL
14strabismus10.6DRD2, PRL, SST
15ossifying fibroma10.6SST, SSTR5
16fallopian tube clear cell adenocarcinoma10.6IGF1, PRL, SST
17carcinoma of the vocal tract10.6IGF1, MEN1, SST
18lung large cell carcinoma10.6NGFR, SST
19lethal arteriopathy syndrome due to fibulin-4 deficiency10.6AIP, MEN1
20medich giant platelet syndrome10.6AIP, MEN1
21lipid-rich carcinoma10.5GNRH1, PRL, SST
22sost-related sclerosing bone dysplasia10.5IGF1, PRL, SST
23fibrosclerosis of breast10.5IGF1, PRL, TGFB1
24retinal dystrophies primarily involving bruch's membrane10.5ESR1, IGF1, PRL
25thrombocytosis10.5FGF2, TGFB1
26pericardial mesothelioma10.5FGF2, TGFB1
27adrenal carcinoma10.5GNRH1, PRL, SST
28medullary thyroid carcinoma, familial10.5MEN1, SST, SSTR5
29asthma susceptibility 510.4ESR1, GNRH1
30riedel's fibrosing thyroiditis10.4ESR1, PRL, SHBG
31symmastia10.4DRD2, PRL
32neuropathy, hereditary sensory and autonomic, type vi10.4FGF2, IGF1, SST
33myoclonic cerebellar dyssynergia10.4ESR1, PRL, SHBG
34central nervous system hemangioma10.4IGF1, PRL, SHBG
35lymphedema10.4IGF1, SST, TGFB1
36dysostosis10.4ESR1, IGF1, TGFB1
37botulism10.3ESR1, SHBG
38gaucher's disease10.3GNRH1, PRL, SHBG
39pancreatic gastrinoma10.3MEN1, SST, VIP
40cetp-related hyperalphalipoproteinemia10.3GNRH1, IGF1
41hematocele of tunica vaginalis testis10.3IGF1, SHBG
42hypothalamic neoplasm10.3GNRH1, PRL
43gender identity disorder10.3GNRH1, PRL, SHBG
44scrotum paget's disease10.3FGF2, TGFB1
45gestational choriocarcinoma10.3IGF1, SHBG, SST
46short bowel syndrome10.3IGF1, SHBG, SST
47glaucoma iridogoniodysgenesia10.3AIP, IGF1, SST
48benign paroxysmal positional nystagmus10.3GNRH1, PRL, SHBG
49kartagener syndrome10.3IGF1, SST, VIP
50naegeli-franceschetti-jadassohn syndrome/dermatopathia pigmentosa reticularis10.3FGF2, NGFR, TGFB1

Graphical network of the top 20 diseases related to Prolactinoma:



Diseases related to prolactinoma

Symptoms for Prolactinoma

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Symptoms:

 52 (show all 51)
  • male hypogonadism
  • hypogonadotrophic hypogonadism
  • amenorrhea
  • female hypogonadism
  • hypogonadism
  • abnormality of the menstrual cycle
  • ptosis
  • progressive visual loss
  • blindness
  • diplopia
  • gynecomastia
  • impotence
  • delayed puberty
  • anterior hypopituitarism
  • growth hormone excess
  • menstrual irregularities
  • decreased fertility in females
  • osteopenia
  • osteoporosis
  • pallor
  • sudden central visual loss
  • seizures
  • headache
  • cranial nerve paralysis
  • vomiting
  • nausea and vomiting
  • vertigo
  • hypotension
  • decreased circulating acth level
  • low gonadotropins (secondary hypogonadism)
  • easy fatigability
  • cranial nerve vi palsy
  • fourth cranial nerve palsy
  • internal ophthalmoplegia
  • secondary growth hormone deficiency
  • pituitary hypothyroidism
  • abnormality of hair density
  • central adrenal insufficiency
  • adrenocorticotropin (acth) deficient adrenal insufficiency
  • adrenocorticotropic hormone deficiency
  • decreased fertility in males
  • oculomotor nerve palsy
  • hemianopsia
  • fatigue
  • abnormality of the pituitary gland
  • decreased female libido
  • dyspareunia
  • heteronymous hemianopia
  • bitemporal hemianopia
  • erectile abnormalities
  • galactorrhea

Drugs & Therapeutics for Prolactinoma

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Drugs for Prolactinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 16)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
CabergolinePhase 4, Phase 2, Phase 34681409-90-754746
Synonyms:
(8R)-6-Allyl-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)ergoline-8-carboxamide
(8R)-6-allyl-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)ergoline-8-carboxamide
(8beta)-N-[3-(dimethylamino)Propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)-ergoline-8-carboxamide
(8beta)-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-6-(prop-2-en-1-yl)ergoline-8-carboxamide
(8beta)-N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)-ergoline-8-carboxamide
(8beta)-N-[3-(dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-prop-2-en-1-ylergoline-8-carboxamide
1-((6-Allylergolin-8beta-yl)carbonyl)-1-(3-(dimethylamino)propyl)-3-ethylurea
1-Ethyl-3-(3'-dimethylamionpropyl)-2-(6'-allylergoline-8'beta-carbonyl)urea
1-[(6-Allylergoline-8beta-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea
1-[(6-allylergoline-8beta-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea
1-ethyl-2-(3'-dimethylaminopropyl)-3-(6'-allylergoline-8'-beta-carbonyl)urea diphosphate
1-ethyl-3-(3'-dimethylamionpropyl)-2-(6'-allylergoline-8'beta-carbonyl)urea
81409-90-7
85329-89-1 (diphosphate)
AC-14150
AC1L1HO0
AC1Q5OQ0
BIDD:GT0775
BRD-K86882815-001-01-6
BRN 6020775
C08187
C26H37N5O2
CG-101
CHEBI:3286
 
CHEMBL1201087
CID54746
Cabaser
Cabaser (TN)
Cabaseril
Cabergolina
Cabergolina [Spanish]
Cabergoline
Cabergoline (JAN/USAN/INN)
Cabergoline [USAN:BAN:INN]
Cabergolinum
Cabergolinum [Latin]
D00987
DB00248
Dostinex
Dostinex (TN)
FCE-21336
FT-0081285
Galastop
HMS2090A09
LS-64370
MolPort-003-845-557
Sogilen
UNII-LL60K9J05T
cabergoline
2Dopamine agonistsPhase 4, Phase 2, Phase 3611
3
DopaminePhase 4, Phase 2, Phase 3367851-61-6, 62-31-7681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
KBio1_000780
 
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
4
SomatostatinPhase 2, Phase 321238916-34-6, 51110-01-153481605
Synonyms:
growth hormone-inhibiting hormone (GHIH)
 
somatotropin release-inhibiting factor (SRIF)
somatotropin release-inhibiting hormone
5
LapatinibApproved March 2007Phase 2296231277-92-2, 388082-78-8208908, 9941095
Synonyms:
1xkk
231277-92-2
388082-78-8
4-[[3-Chloro-4-(3-fluorobenzyloxy)phenyl]amino]-6-[5-[[(2-methanesulfonylethyl)amino]methyl]furan-2-yl]quinazoline
AB1004631
AC-1314
AC1L4LL4
AKOS005145766
CHEBI:49603
CHEMBL1201179
CHEMBL554
CID11557040
CID208908
D04024
D08108
DB01259
DB02584
EN002712
FMM
GSK 572016
GSK572016
GW 572016
GW 572016X
GW-2016
GW-572016
GW-572016F
GW2016
GW572016
HMS2089H10
I01-1247
 
Kinome_3684
Kinome_3685
LAPATINIB DITOSYLATE MONOHYDRATE
LS-187029
LS-187771
Lapatinib
Lapatinib (INN)
Lapatinib Ditosylate
Lapatinib [INN]
Lapatinib ditosylate
Lapatinib ditosylate (USAN)
Lapatinib tosilate hydrate
Lapatinib tosilate hydrate (JAN)
Lapatinib, Tykerb, GW572016
N-(3-Chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-((2-methylsulfonylethylamino)methyl)-2-furyl)quinazolin-4-amine
N-(3-Chloro-4-{[(3-fluorophenyl)methyl]oxy}phenyl)-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furanyl]-4-quinazolinamine
N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine
N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine
N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE
N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine
NCGC00167507-01
NSC745750
TL80090051
Tycerb
Tykerb
Tykerb (TN)
Tyverb
UNII-0VUA21238F
lapatinib
lapatinib ditosylate
nchembio866-comp20
6CLOMIPHENEPhase 2161
7
EnclomiphenePhase 216115690-57-0
Synonyms:
 
Clomiphene trans-form
8
Citric AcidPhase 2106377-92-9311
Synonyms:
2-Hydroxy-1,2,3-propanetricarboxylate
2-Hydroxy-1,2,3-propanetricarboxylic acid
2-Hydroxytricarballylic acid
3-Carboxy-3-hydroxypentane-1,5-dioate
3-Carboxy-3-hydroxypentane-1,5-dioic acid
Aciletten
Anhydrous citrate
Anhydrous citric acid
Chemfill
Citraclean
 
Citrate
Citretten
Citric acid
Citro
Citronensäure
E 330
Hydrocerol A
Kyselina citronova
Suby G
Uro-trainer
beta-Hydroxytricarballylate
beta-Hydroxytricarballylic acid
9
BromocriptinePhase 23025614-03-331101
Synonyms:
(5'alpha)-2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-3',6',18-trioxoergotaman
(5'alpha)-2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)ergotaman-3',6',18-trione
(5'alpha)-2-bromo-12'-hydroxy-5'-(2-methylpropyl)-2'-(propan-2-yl)-3',6',18-trioxoergotaman
(5'alpha)-2-bromo-12'-hydroxy-5'-isobutyl-2'-isopropyl-3',6',18-trioxoergotaman
(6aR,9R)-5-Bromo-N-((2R,5S,10aS,10bS)-10b-hydroxy-5-isobutyl-2-isopropyl-3,6-dioxooctahydro-2H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
2-Bromo-12'-hydroxy-2'-(1-methylethyl)-5'-alpha-(2-methylpropyl)ergotamin-3',6',18-trione
2-Bromo-alpha-ergocryptine
2-Bromo-alpha-ergokryptin
2-Bromo-alpha-ergokryptine
2-Bromoergocryptine Methanesulfonate
2-Bromoergokryptine
2-bromo-α-ergocryptine
2-bromo-α-ergokryptin
2-bromo-α-ergokryptine
22260-51-1 (mesylate (salt))
25614-03-3
AC-13601
AC1L1KXS
AC1Q2716
Alti-Bromocriptine
Apo-Bromocriptine
BIDD:GT0464
BPBio1_001131
BRD-K14496212-001-01-1
Bagren
Biomol-NT_000005
Bromergocryptine
Bromocriptin
Bromocriptina
Bromocriptina [INN-Spanish]
Bromocriptine (USAN/INN)
Bromocriptine Methanesulfonate
Bromocriptine [BAN]
Bromocriptine [USAN:BAN:INN]
 
Bromocriptine methanesulfonate
Bromocriptinum
Bromocriptinum [INN-Latin]
Bromocryptin
Bromocryptine
Bromoergocriptine
Bromoergocryptine
C06856
C32H40BrN5O5
CB-154
CCRIS 3244
CHEBI:3181
CHEMBL493
CID31101
D03165
DB01200
EINECS 247-128-5
Ergocryptine, 2-bromo- (8CI)
Ergoset
LS-64540
Lopac0_000171
MolPort-002-512-064
NCGC00024584-04
NCI60_001365
NSC169774
PDSP2_001500
Parlodel
Parlodel Snaptabs
Prestwick0_000121
Prestwick1_000121
Prestwick2_000121
SPBio_002101
UNII-3A64E3G5ZO
bromocriptine
nchembio873-comp18
10CitrateNutraceuticalPhase 21063
11
CurcuminPhase 1131458-37-7969516
Synonyms:
1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
1,9-Bis(4-hydroxy-3-methoxyphenyl)-2,7-nonadiene-4,6-dione
C.I. Natural Yellow 3
CI Natural Yellow 3
Cucurmin
Curcuma
Curcumin
Curcumin I
Diferaloylmethane
Diferuloylmethane
Gelbwurz
Golden seal
Haidr
Halad
Haldar
Halud
Hydrastis
 
Indian saffron
Indian turmeric
Kacha haldi
Kurkumin [czech]
Merita earth
Natural yellow 3
Orange root
Safran D'inde
Souchet
Terra merita
Tumeric yellow
Turmeric
Turmeric (>98% curcurmin)
Turmeric oleoresin (79%-85% curcumin)
Turmeric yellow
Yellow ginger
Yellow puccoon
Yellow root
Yo-kin
Zlut prirodni 3 [Czech]
12
protease inhibitorsPhase 15157
Synonyms:
 
protease inhibitors
13glucocorticoidsPhase 14756
14
DexamethasonePhase 1200150-02-25743
Synonyms:
(3H)-Dexamethasone
.delta.(sup 1)-9-.alpha.-Fluoro-16-.alpha.-methylcortisol
.gamma.corten
1-Dehydro-16.alpha.-methyl-9.alpha.-fluorohydrocortisone
1-Dehydro-16alpha -methyl-9alpha -fluorohydrocortisone
1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone
1-Dehydro-16α-methyl-9α-fluorohydrocortisone
137098-19-2
16-alpha-Methyl-9-alpha-fluoro-1-dehydrocortisol
16-alpha-Methyl-9-alpha-fluoro-delta(sup 1)-hydrocortisone
16-alpha-Methyl-9-alpha-fluoro-delta1-hydrocortisone
16-alpha-Methyl-9-alpha-fluoroprednisolone
16.alpha.-Methyl-9.alpha.-fluoro-1-dehydrocortisol
16.alpha.-Methyl-9.alpha.-fluoroprednisolone
16alpha -Methyl-9alpha -fluoro-1-dehydrocortisol
16alpha -Methyl-9alpha -fluoroprednisolone
16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol
16alpha-Methyl-9alpha-fluoro-delta(sup 1)-hydrocortisone
16alpha-Methyl-9alpha-fluoroprednisolone
16α-Methyl-9α-fluoro-1-dehydrocortisol
23495-06-9
31375_FLUKA
46165_FLUKA
46165_RIEDEL
50-02-2
8054-59-9
9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11alpha -methylpregna-1,4-diene-3,20-dione
9-Fluoro-16-methylprednisolone
9-alpha-Fluoro-16-alpha-methylprednisolone
9.alpha.-Fluoro-16.alpha.-methylprednisolone
906422-84-2
9A-FLUORO-16BETA-METHYLPREDNISOLONE
9alpha -Fluoro-16alpha -methylprednisolone
9alpha-Fluoro-16alpha-methylprednisolone
9alpha-fluoro-16alpha-methyl-Prednisolone
9α-Fluoro-16α-methylprednisolone
AC-11056
AC1L1L1H
AC1Q29DM
AI3-50934
Adexone
Aeroseb-D
Aeroseb-Dex
Aeroseb-dex
Ak Dex Oph Otic Soln 0.1%
Alcon Brand of Dexamethasone
Anaflogistico
Aphtasolon
Aphthasolone
Apo-dexamethasone
Auxiron
Azimycin (veterinary)
Azium
Azium (Veterinary)
Azium (veterinary)
BIDD:ER0494
BIDD:PXR0060
BRD-K38775274-001-02-3
BRD-K38775274-001-06-4
BSPBio_000995
Bisu DS
Bisu Ds
C15643
C22H29FO5
CCRIS 7067
CHEBI:41879
CHEMBL384467
CID5743
CPD-10549
CPD001227192
Calonat
Corson
Corsone
Cortisumman
D00292
D003907
D1756_SIGMA
D4902_SIGMA
D6645_SIGMA
D8893_SIGMA
D9184_SIGMA
DB01234
DEX
DEXA
DEXONE 0.5
DEXONE 0.75
DEXONE 1.5
DEXONE 4
DXM
DXMS
Decacort
Decacortin
Decaderm
Decadron
Decadron (TN)
Decadron Tablets, Elixir
Decadron, Dexamethasone
Decadron-LA
Decadron-La
Decagel
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Decaject L.A.
Decaject-L.A.
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Decameth
Decasone
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Dectancyl
Dekacort
Delta1-9alpha-Fluoro-16alpha-methylcortisol
Deltafluorene
Dergramin
Deronil
Desadrene
Desametasone
Desametasone [DCIT]
Desametasone [Dcit]
Desamethasone
Desameton
Deseronil
Dex-Ide
Dex-ide
Dexa
Dexa Mamallet
Dexa mamallet
Dexa-Cortidelt
Dexa-Cortisyl
Dexa-Mamallet
Dexa-Scheroson
Dexa-Sine
Dexa-cortidelt
Dexa-cortisyl
Dexa-scheroson
Dexa-sine
Dexacen-4
Dexacidin
Dexacort
Dexacortal
Dexacortin
Dexadeltone
Dexafarma
Dexair
Dexalona
Dexaltin
Dexametasona
Dexametasona [INN-Spanish]
Dexametasone
 
Dexameth
Dexamethansone
Dexamethasone
Dexamethasone (JP15/USP/INN)
Dexamethasone Acetate
Dexamethasone Alcohol
Dexamethasone Base
Dexamethasone Intensol
Dexamethasone Sodium Phosphate
Dexamethasone [INN:BAN:JAN]
Dexamethasone alcohol
Dexamethasone base
Dexamethasone intensol
Dexamethasone-omega
Dexamethasonum
Dexamethasonum [INN-Latin]
Dexamethazone
Dexamonozon
Dexapolcort
Dexapos
Dexaprol
Dexason
Dexasone
Dexasone 0.5mg
Dexasone 0.75mg
Dexasone 4mg
Dexasporin
Dexinolon
Dexinoral
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Dexone 0.5
Dexone 0.75
Dexone 1.5
Dexone 4
Dexonium
Dexpak
Dextelan
Dezone
Dinormon
Dxms
ECR Brand of Dexamethasone
EINECS 200-003-9
FT-0080377
Fluormethylprednisolone
Fluormone
Fluorocort
Fortecortin
Foy Brand of Dexamethasone
Gammacorten
HL-dex
HMS1792A17
HMS1990A17
HMS2089N13
HSDB 3053
Hexadecadrol
Hexadrol
Hexadrol Elixir
Hexadrol Tablets
Hexadrol elixir
Hl-Dex
Hl-dex
I06-1196
ICN Brand of Dexamethasone
IontoDex
Isopto-Dex
Isopto-dex
LS-7300
Lokalison F
Lokalison f
Loverine
Luxazone
MK 125
MLS001055412
MLS001332507
MLS001332508
Maxidex
Maxidex Ont 0.1%
Maxidex Sus 0.1%
Maxitrol
Mediamethasone
Merck Brand of Dexamethasone
Merz Brand 1 of Dexamethasone
Merz Brand 2 of Dexamethasone
Methylfluorprednisolone
Mexidex
Millicorten
MolMap_000018
MolPort-003-846-433
Mymethasone
NCGC00091019-01
NCGC00091019-02
NCGC00091019-03
NCGC00091019-04
NCGC00091019-05
NCI60_003067
NSC 34521
NSC34521
Naquasone (veterinary)
Neomycin and polymyxin b sulfates and dexamethasone
Neomycin and polymyxin b sulphates and dexamethasone
OTO-104
Ocu-Trol
Ocu-trol
Oradexon
PHL-dexamethasone
PMS-dexamethasone
Pet Derm III
Pet Derm Iii
Pet derm III
Pet-Derm Iii
Pms Dexamethasone Elixir 0.5mg/5ml
Policort
Posurdex
Prednisolon F
Prednisolon f
Prednisolone F
Prednisolone f
Prodex
S1322_Selleck
SAM002548948
SGCUT00126
SK-Dexamethasone
SK-dexamethasone
SMP1_000092
SMR000857119
SMR001227192
ST50307091
Sandoz dexamethasone
Sk-Dexamethasone
Spectrum5_002019
Spoloven
Sunia Sol D
Sunia sol D
Superprednol
TL8003317
Tobradex
Tobramycin and dexamethasone
Tresaderm (veterinary)
Turbinaire
UNII-7S5I7G3JQL
Visumetazone
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ G1
ZINC03875332
alpha -Fluoro-16-alpha -methylcortisol
delta(Sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta(sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta1-9alpha-Fluoro-16alpha-methylcortisol
dexamethasone
nchembio809-comp2
to_000038
15Dexamethasone acetatePhase 120011177-87-3
16insulin4401

Interventional clinical trials:

(show all 16)
idNameStatusNCT IDPhase
1Cardiac Valve Complications in Prolactinomas Treated With CabergolineCompletedNCT00460616Phase 4
2Response to Cabergoline and Pasireotide in Non-functioning Pituitary Adenomas and Resistant ProlactinomasCompletedNCT01620138Phase 2, Phase 3
3Clomiphene in Males With Prolactinomas and Persistent HypogonadismCompletedNCT00697814Phase 2
4Targeted Therapy With Lapatinib in Patients With Recurrent Pituitary Tumors Resistant to Standard TherapyRecruitingNCT00939523Phase 2
5Bromocriptine Quick Release (BCQR) as Adjunct Therapy in Type 1 DiabetesRecruitingNCT02544321Phase 2
6Temozolomide in Treating Patients With Invasive Pituitary TumorsWithdrawnNCT00601289Phase 2
7Turmeric Effect on Reduction of Serum Prolactin and Related Hormonal Change and Adenoma Size in Prolactinoma PatientsRecruitingNCT01344291Phase 1
8Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell LeukemiaTerminatedNCT01088763Phase 1
9Insulin Resistance in Women With ProlactinomaCompletedNCT00481299
10Dopamine Agonists Withdrawal Study of Invasive Prolactinomas Involving the Cavernous SinusRecruitingNCT02536261
11Interdisciplinary Pituitary Disorders Centre of Excellence: Assessment of Patient Education ToolsRecruitingNCT01775332
12PITUItary Carcinoma or Aggressive Tumors REgistry -LyonRecruitingNCT02854228
13Prevalence of Pituitary Incidentaloma in Relatives of Patients With Pituitary AdenomaRecruitingNCT00598949
14Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPARecruitingNCT00461188
15Efficacy of Rapid Escalation of Cabergoline in Comparison to Conventional Dosing in Prolactin Secreting Macroadenomas.RecruitingNCT01143584
16Rhinological Outcomes in Endonasal Pituitary SurgeryActive, not recruitingNCT01504399

Search NIH Clinical Center for Prolactinoma


Cochrane evidence based reviews: prolactinoma

Genetic Tests for Prolactinoma

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Genetic tests related to Prolactinoma:

id Genetic test Affiliating Genes
1 Prolactinoma, Familial25

Anatomical Context for Prolactinoma

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MalaCards organs/tissues related to Prolactinoma:

34
Pituitary, Bone, Thyroid, T cells, Breast, Brain, Heart

Animal Models for Prolactinoma or affiliated genes

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MGI Mouse Phenotypes related to Prolactinoma:

39 (show all 21)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053758.3DRD2, ESR1, IGF1, NGFR, PRKAR1A, TGFB1
2MP:00053717.5BMP4, DRD2, ESR1, IGF1, NGFR, THBS1
3MP:00028737.3BMP4, DRD2, ESR1, GNRH1, IGF1, NGFR
4MP:00053707.2AIP, BMP4, DRD2, ESR1, GNRH1, MEN1
5MP:00107717.1AIP, BMP4, DRD2, ESR1, GNRH1, IGF1
6MP:00053677.1BMP4, DRD2, ESR1, GNRH1, IGF1, NGFR
7MP:00036317.0BMP4, DRD2, ESR1, FGF2, GNRH1, IGF1
8MP:00020066.9AIP, DRD2, ESR1, FGF2, GNRH1, IGF1
9MP:00053886.8BMP4, DRD2, ESR1, IGF1, NGFR, PRKAR1A
10MP:00053696.6BMP4, DRD2, ESR1, FGF2, IGF1, MEN1
11MP:00053816.6BMP4, DRD2, ESR1, GNRH1, MEN1, NGFR
12MP:00053976.5BMP4, DRD2, ESR1, FGF2, GNRH1, IGF1
13MP:00053846.4AIP, BMP4, DRD2, ESR1, FGF2, IGF1
14MP:00053896.4BMP4, DRD2, ESR1, FGF2, GNRH1, IGF1
15MP:00053876.2DRD2, ESR1, GNRH1, IGF1, MEN1, NGFR
16MP:00053905.9BMP4, DRD2, ESR1, FGF2, GNRH1, IGF1
17MP:00053795.9AIP, BMP4, DRD2, ESR1, GNRH1, IGF1
18MP:00053855.8AIP, BMP4, DRD2, ESR1, FGF2, IGF1
19MP:00107685.6AIP, BMP4, DRD2, ESR1, FGF2, IGF1
20MP:00053785.6AIP, BMP4, DRD2, ESR1, GNRH1, IGF1
21MP:00053764.5AIP, BMP4, DRD2, ESR1, FGF2, GNRH1

Publications for Prolactinoma

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Articles related to Prolactinoma:

(show top 50)    (show all 680)
idTitleAuthorsYear
1
Hypopituitarism patterns among adult males with prolactinomas. (27038873)
2016
2
Predictive Factor of Surgical Efficacy in Male Patients with Prolactinoma. (27594148)
2016
3
Pituitary Prolactinoma Imaged by 99mTc-Sestamibi SPECT/CT in a Multiple Endocrine Neoplasia Type 1 Patient. (26828146)
2016
4
Successful treatment of a prolactinoma with the antipsychotic drug aripiprazole. (27284453)
2016
5
Pineal Diffuse Large B-Cell Lymphoma Concomitant With Pituitary Prolactinoma: Possible Correlation Between 2 Distinguished Pathologies: A Case Report. (26937937)
2016
6
Are there any causes for increased thyroid volume in women with prolactinoma? (26067294)
2015
7
ENDOCRINOLOGY IN PREGNANCY: Management of the pregnant patient with a prolactinoma. (25805896)
2015
8
Rapid improvement in visual loss with cabergoline treatment in a giant prolactinoma case: 5 years survey. (25789596)
2015
9
Endoscopic transsphenoidal treatment of a prolactinoma patient with brain and optic chiasmal herniations. (24820730)
2014
10
Differential effects of estrogen and estrogen receptor antagonist, ICI 182 780, on the expression of calbindin-D9k in rat pituitary prolactinoma GHa88 cells. (25674214)
2014
11
Giant prolactinoma presenting as a skull base tumor with erosion of the cervical vertebrae: pronounced responsiveness to dopamine agonist treatment. (25162753)
2014
12
Preclinical Atherosclerosis in Patients with Prolactinoma. (24325995)
2013
13
The expression of AIB1 correlates with cellular proliferation in human prolactinomas. (23433587)
2013
14
Thrombospondin-1 (TSP-1) analogs ABT-510 and ABT-898 inhibit prolactinoma growth and recover active pituitary transforming growth factor-I^1 (TGF-I^1). (22700773)
2012
15
A Case Report and Review of Hyperprolactinemia that is not Prolactinoma. (21672707)
2011
16
Proteomic analysis of prolactinoma cells by immuno-laser capture microdissection combined with online two-dimensional nano-scale liquid chromatography/mass spectrometry. (20205839)
2010
17
Double pituitary prolactinoma. (21051581)
2010
18
Aggressive prolactinoma in a child related to germline mutation in the ARYL hydrocarbon receptor interacting protein (AIP) gene. (21340166)
2010
19
Valvular heart disease and the use of cabergoline for the treatment of prolactinoma. (19128367)
2009
20
Hyperprolactinemia and prolactinomas. (18226731)
2008
21
Inhibitory effect of thalidomide on the growth, secretory function and angiogenesis of estrogen-induced prolactinoma in Fischer 344 rats. (16846617)
2006
22
Transsphenoidal approach to prolactinomas]. (16855780)
2006
23
Metastatic prolactinoma: case report with immunohistochemical assessment for p53 and Ki-67 antigens. (16258673)
2005
24
Long-term efficacy of bromocriptine in macroprolactinomas and giant prolactinomas in men. (16379032)
2005
25
Squash smear findings of spherical amyloid in pituitary prolactinoma. A case report. (15192968)
2004
26
Prevalence of MEN 1 in patients with prolactinoma. MEN1 Study Group of the Hospital de la Santa Creu i Sant Pau of Barcelona. (10396374)
1999
27
Prolactin decrease and shift to a normal-like isoform profile during treatment with quinagolide in a patient affected by an invasive prolactinoma. (9258810)
1997
28
The outcome of hypophysectomy for prolactinomas in the era of dopamine agonist therapy. (8759184)
1996
29
Arrested puberty associated with apoplectic prolactinoma in a male adolescent. (7758013)
1995
30
Eruptive skin tags and keratoacanthomas in a patient with prolactinoma and colonic polyposis. (8075462)
1994
31
Circulating fibroblast growth factor-like autoantibodies in two patients with multiple endocrine neoplasia type 1 and prolactinoma. (7989454)
1994
32
Clinical application of 11C-NMSP to the patients with pituitary adenoma other than prolactinoma]. (8345693)
1993
33
Increased plasma VIP concentration in patients with prolactinoma. (1345563)
1992
34
Influence of pregnancy on the serum prolactin level following prolactinoma surgery. (1950339)
1991
35
Enlarged adenomectomy for enclosed prolactinomas: a preliminary study of 26 cases. (2399846)
1990
36
Human pituitary somatotroph adenoma and prolactinoma: an ultrastructural and immunoelectron microscopical study. (2213957)
1990
37
Prolactinoma in a middle-aged man with an osteoporotic fracture. (2763547)
1989
38
Ultrastructural study of prolactinoma after bromocriptine therapy. (3251048)
1988
39
Successful treatment of infertility in a man with a bromocriptine-resistant prolactinoma. (3117595)
1987
40
Transient intrasellar collection of air during bromocriptine treatment of a prolactinoma. (3762918)
1986
41
Effect of hyperprolactinemia induced by prolactinoma (MtT/F84) on the accessory sexual organs of male rat. (3570843)
1986
42
Prolactinoma and bromocriptine therapy. (3528940)
1986
43
Pharmacokinetics of oral terguride in patients with a prolactinoma. (3732377)
1986
44
Asymptomatic hyperprolactinaemia and prolactinoma in the general population--mass screening by paired assays of serum prolactin. (3621622)
1986
45
Ultrastructural localization of prolactin in estrogen-induced prolactinoma of the rat pituitary. Experimental models for the human prolactinomas and the effects of bromocriptine. (3776530)
1986
46
Subarachnoid metastases from a prolactinoma. (4080058)
1985
47
Visual function in prolactinoma patients treated with bromocriptine. (4069600)
1985
48
Recurrence of hyperprolactinemia after selective transsphenoidal adenomectomy in women with prolactinoma. (6866052)
1983
49
Restoration of oestrogen-positive feedback effect on LH release in women with prolactinoma by transsphenoidal surgery. (6289583)
1982
50
Rapid changes of prolactinoma volume after withdrawal and reinstitution of bromocriptine. (7263835)
1981

Variations for Prolactinoma

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Cosmic variations for Prolactinoma:

8
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA Conf
1COSM771PIK3CApituitary,NS,adenoma,PRLc.3073A>Gp.T1025A0
2COSM483HRASpituitary,NS,adenoma,PRLc.35G>Tp.G12V0
3COSM482HRASpituitary,NS,adenoma,PRLc.34G>Cp.G12R0
4COSM760PIK3CApituitary,NS,adenoma,PRLc.1624G>Ap.E542K0

Expression for genes affiliated with Prolactinoma

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Search GEO for disease gene expression data for Prolactinoma.

Pathways for genes affiliated with Prolactinoma

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Pathways related to Prolactinoma according to GeneCards Suite gene sharing:

(show all 26)
idSuper pathwaysScoreTop Affiliating Genes
19.7GNRH1, SHBG
29.5BMP4, FGF2, IGF1
39.4FGF2, IGF1, TGFB1
49.4FGF2, IGF1, TGFB1
59.0BMP4, FGF2, IGF1, TGFB1
68.9IGF1, TGFB1, THBS1
7
Show member pathways
8.9FGF2, TGFB1, THBS1
8
Show member pathways
8.9FGF2, TGFB1, THBS1
9
Show member pathways
8.8BMP4, TGFB1, THBS1
108.8BMP4, TGFB1, THBS1
118.4BMP4, FGF2, IGF1, NGFR, TGFB1
128.4BMP4, FGF2, IGF1, NGFR, TGFB1
138.2ESR1, FGF2, IGF1, TGFB1, THBS1
148.2ESR1, FGF2, IGF1, TGFB1, THBS1
158.2BMP4, FGF2, GNRH1, IGF1, PRKAR1A, TGFB1
168.2FGF2, IGF1, NGFR, PRL, THBS1
17
Show member pathways
8.2DRD2, FGF2, IGF1, NGFR, THBS1
18
Show member pathways
8.1BMP4, FGF2, GNRH1, IGF1, NGFR, TGFB1
19
Show member pathways
8.1BMP4, FGF2, GNRH1, IGF1, NGFR, TGFB1
20
Show member pathways
7.9BMP4, FGF2, GNRH1, IGF1, NGFR, PRL
21
Show member pathways
7.9BMP4, ESR1, FGF2, GNRH1, IGF1, PRKAR1A
22
Show member pathways
7.6BMP4, FGF2, GNRH1, IGF1, NGFR, PRKAR1A
23
Show member pathways
7.6BMP4, FGF2, GNRH1, IGF1, NGFR, PRKAR1A
24
Show member pathways
7.6BMP4, FGF2, GNRH1, IGF1, NGFR, PRKAR1A
25
Show member pathways
7.6BMP4, FGF2, GNRH1, IGF1, NGFR, PRKAR1A
26
Show member pathways
5.2DRD2, ESR1, FGF2, GNRH1, IGF1, MEN1

GO Terms for genes affiliated with Prolactinoma

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Cellular components related to Prolactinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1platelet alpha granule lumenGO:00310939.5IGF1, TGFB1, THBS1
2perikaryonGO:00432049.0DRD2, ESR1, GNRH1, NGFR
3extracellular spaceGO:00056157.4BMP4, FGF2, GNRH1, IGF1, SST, TGFB1
4extracellular regionGO:00055765.8BMP4, FGF2, GNRH1, IGF1, NGFR, PRL

Biological processes related to Prolactinoma according to GeneCards Suite gene sharing:

(show all 45)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of phospholipase C activityGO:001086310.6ESR1, FGF2
2osteoblast developmentGO:000207610.5ESR1, MEN1
3organ inductionGO:000175910.5BMP4, FGF2
4positive regulation of transcription regulatory region DNA bindingGO:200067910.4IGF1, TGFB1
5regulation of branching involved in prostate gland morphogenesisGO:006068710.4BMP4, ESR1
6embryonic morphogenesisGO:004859810.4BMP4, FGF2
7negative regulation of production of miRNAs involved in gene silencing by miRNAGO:190379910.4ESR1, TGFB1
8hyaluronan catabolic processGO:003021410.3FGF2, TGFB1
9common-partner SMAD protein phosphorylationGO:000718210.3BMP4, TGFB1
10regulation of cartilage developmentGO:006103510.3BMP4, TGFB1
11regulation of protein import into nucleusGO:004230610.3BMP4, TGFB1
12cell activationGO:000177510.3IGF1, TGFB1
13positive regulation of pri-miRNA transcription from RNA polymerase II promoterGO:190289510.3BMP4, TGFB1
14positive regulation of SMAD protein import into nucleusGO:006039110.2BMP4, TGFB1
15positive regulation of smooth muscle cell proliferationGO:004866110.1BMP4, FGF2, IGF1
16negative regulation of cell cycleGO:004578610.1BMP4, MEN1, TGFB1
17positive regulation of endothelial cell proliferationGO:00019389.9BMP4, FGF2, VIP
18positive regulation of endothelial cell apoptotic processGO:20003539.9BMP4, THBS1
19positive regulation of fibroblast proliferationGO:00481469.9ESR1, IGF1, TGFB1
20positive regulation of osteoblast differentiationGO:00456699.9BMP4, FGF2, IGF1
21negative regulation of epithelial cell proliferationGO:00506809.9BMP4, MEN1, TGFB1
22positive regulation of chemotaxisGO:00509219.9TGFB1, THBS1
23positive regulation of fibroblast migrationGO:00107639.7TGFB1, THBS1
24female pregnancyGO:00075659.6GNRH1, IGF1, PRL, TGFB1
25positive regulation of endothelial cell migrationGO:00105959.6BMP4, FGF2, THBS1
26positive regulation of blood vessel endothelial cell migrationGO:00435369.6FGF2, TGFB1, THBS1
27negative regulation of extrinsic apoptotic signaling pathwayGO:20012379.6BMP4, IGF1, THBS1
28platelet degranulationGO:00025769.5IGF1, TGFB1, THBS1
29agingGO:00075689.4FGF2, GNRH1, IGF1, TGFB1
30regulation of gene expressionGO:00104689.4BMP4, GNRH1, IGF1, TGFB1
31response to testosteroneGO:00335749.4BMP4, GNRH1, THBS1
32wound healingGO:00420609.3BMP4, FGF2, TGFB1
33negative regulation of blood vessel endothelial cell migrationGO:00435379.3FGF2, TGFB1, THBS1
34cellular response to growth factor stimulusGO:00713639.3BMP4, TGFB1, THBS1
35positive regulation of ERK1 and ERK2 cascadeGO:00703749.3BMP4, DRD2, ESR1, FGF2
36positive regulation of transcription, DNA-templatedGO:00458939.1BMP4, ESR1, FGF2, IGF1, TGFB1
37positive regulation of epithelial cell proliferationGO:00506799.0BMP4, ESR1, FGF2, IGF1, TGFB1
38response to hypoxiaGO:00016668.8DRD2, IGF1, TGFB1, THBS1
39positive regulation of protein kinase B signalingGO:00518978.8FGF2, NGFR, TGFB1, THBS1
40positive regulation of cell migrationGO:00303358.8BMP4, IGF1, TGFB1, THBS1
41activation of MAPK activityGO:00001878.8FGF2, IGF1, THBS1
42positive regulation of cell proliferationGO:00082848.6BMP4, FGF2, IGF1, TGFB1, VIP
43negative regulation of cell proliferationGO:00082858.2BMP4, DRD2, FGF2, GNRH1, MEN1, SST
44positive regulation of transcription from RNA polymerase II promoterGO:00459448.1BMP4, DRD2, ESR1, FGF2, IGF1, MEN1
45negative regulation of apoptotic processGO:00430667.9BMP4, GNRH1, IGF1, NGFR, THBS1, VIP

Molecular functions related to Prolactinoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:00051799.2GNRH1, IGF1, PRL, SST, VIP
2growth factor activityGO:00080839.0BMP4, FGF2, IGF1, TGFB1
3steroid bindingGO:00054969.0ESR1, IGF1, SHBG

Sources for Prolactinoma

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet