PDR
MCID: PRL007
MIFTS: 57

Proliferative Diabetic Retinopathy (PDR) malady

Summaries for Proliferative Diabetic Retinopathy

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MalaCards: Proliferative Diabetic Retinopathy, also known as pigmentary disorder, reticulate, with systemic manifestations, is related to diabetic retinopathy and proliferative vitreoretinopathy. An important gene associated with Proliferative Diabetic Retinopathy is SERPINF1 (serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1), and among its related pathways are Rho Family GTPases and Akt Signaling. The compounds vegf and tyrosine have been mentioned in the context of this disorder. Affiliated tissues include endothelial, eye and monocytes, and related mouse phenotypes are immune system and cardiovascular system.

Aliases & Classifications for Proliferative Diabetic Retinopathy

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8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 56SNOMED-CT, 27ICD9CM, 39NCIt
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Aliases & Descriptions:

proliferative diabetic retinopathy 8 10 44 60
pigmentary disorder, reticulate, with systemic manifestations 60
pdr 8


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Disease Ontology8 DOID:13207
ICD9CM27 362.02
SNOMED-CT56 154679002, 59276001
NCIt39 C84457

Related Diseases for Proliferative Diabetic Retinopathy

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17GeneCards, 18GeneDecks
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Diseases related to Proliferative Diabetic Retinopathy via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 225)
idRelated DiseaseScoreTop Affiliating Genes
1diabetic retinopathy32.3TGFB2, ADM, VTN, SERPINF1, VCAM1, CXCL12
2proliferative vitreoretinopathy31.1TGFB2, ADM, VTN, CTGF, CCL2, HGF
3retinal detachment31.1TGFB2, SERPINF1, VEGFA
4diabetic macular edema31.1SERPINF1, VEGFA
5diabetes mellitus30.9VTN, VCAM1, IGFBP1, SST, ANGPT2, VEGFA
6glaucoma30.8TGFB2, SERPINF1, CTGF, TIMP2
7neovascular glaucoma30.8VEGFA
8macular holes30.7TGFB2, ADM, SERPINF1, PTGDS, MIF, ANGPT2
9diabetic nephropathy30.6ADM, SERPINF1, MIF, CTGF, CCL2, TIMP3
10type 2 diabetes mellitus30.6ADM, VCAM1, CXCL10, IGFBP1, GAD1, CCL2
11proteinuria30.4ADM, VTN, ANGPT2, VEGFA, CTGF, CCL2
12ischemia30.2TGFB2, ADM, VTN, CXCL12, EPHB4, ANGPT2
13retinal disease30.2ADM, SERPINF1, VCAM1, EPHB4, IGFBP1, ANGPT2
14osteoarthritis30.2TGFB2, VCAM1, CXCL12, CXCL10, ANGPT2, CTGF
15leukemia30.2SERPINF1, CXCL12, IGFBP1, ANGPT2
16uveitis30.2TGFB2, SERPINF1, CXCL10, CCL2
17macular retinal edema30.2SERPINF1, CXCL12, VEGFA
18coronary artery disease30.2VTN, VCAM1, IGFBP1, CCL2
19encephalitis30.1VCAM1, CXCL10, CCL2
20malaria29.9MIF
21meningitis29.9CXCL10
22hepatitis29.9CXCL10, HGF, TIMP2
23retinitis11.0
24background diabetic retinopathy10.4
25severe nonproliferative diabetic retinopathy10.4
26vitreous detachment10.4
27diabetic cataract10.4
28cataract10.4
29acromegaly10.3
30type 1 diabetes mellitus10.3
31rubeosis iridis10.3
32retinoschisis10.3
33sleep disorder10.3
34vitreous disease10.3
35paragonimiasis10.2
36amyloidosis10.2
37ischemic retinopathy10.2
38carotid stenosis10.2
39choroiditis10.2
40retinal ischemia10.2
41maturity-onset diabetes of the young10.2
42retinitis pigmentosa10.2
43hemochromatosis10.2
44gestational diabetes10.2
45carotid artery disease10.2
46hypothyroidism10.2
47optic atrophy10.2
48retinal degeneration10.2
49hemochromatosis type 210.2
50autosomal dominant neovascular inflammatory vitreoretinopathy10.2

Graphical network of the top 20 diseases related to Proliferative Diabetic Retinopathy:



Diseases related to proliferative diabetic retinopathy

Clinical Features for Proliferative Diabetic Retinopathy

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Drugs & Therapeutics for Proliferative Diabetic Retinopathy

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Genetic Tests for Proliferative Diabetic Retinopathy

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Anatomical Context for Proliferative Diabetic Retinopathy

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32MalaCards
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MalaCards organs/tissues related to Proliferative Diabetic Retinopathy:

32
Endothelial, Eye, Monocytes, Placenta, Retina, Myeloid, T cells, Tongue

Animal Models for Proliferative Diabetic Retinopathy or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Proliferative Diabetic Retinopathy:

36 (show all 16)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000538710.9SST, ANGPT2, VEGFA, CCL2, TIMP3, TIMP2
2MP:000538510.9TGFB2, HGF, CCL2, CTGF, ANGPT2, EPHB4
3MP:000538410.8GAD1, CTGF, CCL2, HGF, TIMP3, VEGFA
4MP:001076810.8VEGFA, GAD1, CTGF, CCL2, HGF, TIMP3
5MP:000537610.8TIMP3, CCL2, CTGF, GAD1, CXCL10, VCAM1
6MP:000539710.8TIMP2, TIMP3, HGF, CCL2, VEGFA, MIF
7MP:000538110.8CCL2, CTGF, GAD1, VEGFA, ANGPT2, SST
8MP:000287310.7TIMP2, CCL2, CTGF, GAD1, VEGFA, SST
9MP:000537010.7TIMP3, HGF, CCL2, VEGFA, IGFBP1, CXCL12
10MP:000538010.7CTGF, GAD1, EPHB4, VCAM1, ADM, TGFB2
11MP:000301210.6PTGDS, GAD1
12MP:000536910.5EPHB4, CXCL12, TGFB2
13MP:000539110.5TIMP3, ANGPT2, SERPINF1, TGFB2
14MP:000363110.5SERPINF1, GAD1, TIMP2
15MP:000537810.4TIMP3, HGF, CCL2, CTGF, GAD1, VEGFA
16MP:001077110.2TIMP3, CTGF, VEGFA, ANGPT2, PTGDS

Publications for Proliferative Diabetic Retinopathy

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50PubMed
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Articles related to Proliferative Diabetic Retinopathy:

(show top 50)    (show all 574)
idTitleAuthorsYear
1
Gene Expression of IGF1, IGF1R, and IGFBP3 in Epiretinal Membranes of Patients with Proliferative Diabetic Retinopathy: Preliminary Study. (24379526)
2013
2
Randomized clinical trial evaluating intravitreal ranibizumab or saline for vitreous hemorrhage from proliferative diabetic retinopathy. (23370902)
2013
3
Neural Constraints on Visual Acuity in Proliferative Diabetic Retinopathy. (24317136)
2013
4
The outcomes of pars plana vitrectomy without endotamponade for tractional retinal detachment secondary to proliferative diabetic retinopathy. (24195047)
2013
5
Detecting Diabetes Mellitus and Non-Proliferative Diabetic Retinopathy using Tongue Color, Texture, and Geometry Features. (24058014)
2013
6
Association of monocyte chemoattractant protein-1 (MCP-1) 2518A/G polymorphism with proliferative diabetic retinopathy in Korean type 2 diabetes. (23549806)
2013
7
Soluble vascular adhesion protein-1 accumulates in proliferative diabetic retinopathy. (22618595)
2012
8
Intraocular VEGF level as a risk factor for postoperative complications after vitrectomy for proliferative diabetic retinopathy. (22899753)
2012
9
Axial length and proliferative diabetic retinopathy. (22426176)
2012
10
Distribution, reabsorption, and complications of preretinal blood under silicone oil after vitrectomy for severe proliferative diabetic retinopathy. (22222267)
2012
11
Expression of promyelocytic leukemia protein and vascular endothelial growth factor in aqueous humor and vitreous fluid in patients with proliferative diabetic retinopathy. (23092969)
2012
12
Increased IL-6 levels are not related to NF-I_B or HIF-1I+ transcription factors activity in the vitreous of proliferative diabetic retinopathy. (21813290)
2011
13
Treatment of proliferative diabetic retinopathy with anti-VEGF agents. (21294854)
2011
14
Vitreous and plasma concentrations of apelin and vascular endothelial growth factor after intravitreal bevacizumab in eyes with proliferative diabetic retinopathy. (20890241)
2011
15
Metabolic fingerprints of proliferative diabetic retinopathy: an 1H-NMR-based metabonomic approach using vitreous humor. (20375324)
2010
16
Association of preoperative vitreous IL-8 and VEGF levels with visual acuity after vitrectomy in proliferative diabetic retinopathy. (21073666)
2010
17
Entry site treatment to prevent late recurrent postoperative vitreous cavity haemorrhage after vitrectomy for proliferative diabetic retinopathy. (19955203)
2010
18
LSFG findings of proliferative diabetic retinopathy after intravitreal injection of bevacizumab. (22785537)
2010
19
Experience with intravitreal bevacizumab as a preoperative adjunct in 23-G vitrectomy for advanced proliferative diabetic retinopathy. (20491044)
2010
20
Intravitreal bevacizumab for surgical treatment of severe proliferative diabetic retinopathy. (20135139)
2010
21
Roles of endothelin-1 and selected proinflammatory cytokines in the pathogenesis of proliferative diabetic retinopathy: Analysis of vitreous samples. (20015663)
2010
22
Anticardiolipin antibodies in proliferative diabetic retinopathy: An additional risk factor. (23960854)
2009
23
Genetic variations and plasma levels of gelatinase A (matrix metalloproteinase-2) and gelatinase B (matrix metalloproteinase-9) in proliferative diabetic retinopathy. (18552985)
2008
24
Erythropoietin as a retinal angiogenic factor in proliferative diabetic retinopathy]. (18051819)
2007
25
Comparison of vitrectomy alone and combined vitrectomy, phacoemulsification and intraocular lens implantation for proliferative diabetic retinopathy. (17606428)
2007
26
Functional vascular endothelial growth factor -634G>C SNP is associated with proliferative diabetic retinopathy: a case-control study in a Brazilian population of European ancestry. (17259494)
2007
27
The therapeutic effects of angiotensin-converting enzyme inhibitors in severe non-proliferative diabetic retinopathy. (17460429)
2007
28
Rapid resolution of severe disc new vessels in proliferative diabetic retinopathy following a single intravitreal injection of bevacizumab (Avastin). (17073910)
2006
29
Role of monocyte chemotactic protein-1 and nuclear factor kappa B in the pathogenesis of proliferative diabetic retinopathy. (16730843)
2006
30
Elevated intravitreal interleukin-6 levels in patients with proliferative diabetic retinopathy. (17224958)
2006
31
Glial cell line-derived neurotrophic factor in the vitreous of patients with proliferative diabetic retinopathy. (16186306)
2005
32
Immunohistochemical study of extracellular matrix components in epiretinal membranes of vitreoproliferative retinopathy and proliferative diabetic retinopathy. (15945009)
2005
33
Erythropoietin as a retinal angiogenic factor in proliferative diabetic retinopathy. (16120858)
2005
34
Somatostatin molecular variants in the vitreous fluid: a comparative study between diabetic patients with proliferative diabetic retinopathy and nondiabetic control subjects. (16043736)
2005
35
Intravitreous levels of hepatocyte growth factor/scatter factor and vascular cell adhesion molecule-1 in the vitreous fluid of diabetic patients with proliferative retinopathy. (15525877)
2004
36
CD4-CD8 and CD28 expression in T cells infiltrating the vitreous fluid in patients with proliferative diabetic retinopathy: a flow cytometric analysis. (15136323)
2004
37
Diverse NF-kappaB expression in epiretinal membranes after human diabetic retinopathy and proliferative vitreoretinopathy. (14737065)
2004
38
Incidence of proliferative retinopathy and sex-related differences in death rate among patients with diabetes mellitus and sight impairment treated with insulin (according to the data from national diabetic registry)]. (15724607)
2004
39
Production and activation of matrix metalloproteinase-2 in proliferative diabetic retinopathy. (12714657)
2003
40
Interleukin-8, nitric oxide and glutathione status in proliferative vitreoretinopathy and proliferative diabetic retinopathy. (12920337)
2003
41
Free insulin-like growth factor 1 in the vitreous fluid of diabetic patients with proliferative diabetic retinopathy: a case-control study. (12605576)
2003
42
Aggravation of proliferative diabetic retinopathy after laser in situ keratomileusis. (14670438)
2003
43
Membrane conductance of MA1ller glial cells in proliferative diabetic retinopathy. (12095095)
2002
44
Angiotensin converting enzyme inhibiting therapy is associated with lower vitreous vascular endothelial growth factor concentrations in patients with proliferative diabetic retinopathy. (11935151)
2002
45
Proliferative diabetic retinopathy. (11677510)
2001
46
Vitreous levels of insulin-like growth factor-I in patients with proliferative diabetic retinopathy. (11910526)
2001
47
Suppressed expression of tubedown-1 in retinal neovascularization of proliferative diabetic retinopathy. (11687548)
2001
48
Increased vitreous concentrations of human hepatocyte growth factor in proliferative diabetic retinopathy. (10022434)
1999
49
Corneal sensation in insulin dependent and non-insulin dependent diabetics with proliferative retinopathy. (7887155)
1994
50
Asymmetric proliferative diabetic retinopathy and carotid artery disease. (2381700)
1990

Genetic Variations for Proliferative Diabetic Retinopathy

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Expression for genes affiliated with Proliferative Diabetic Retinopathy

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Proliferative Diabetic Retinopathy

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Pathways for genes affiliated with Proliferative Diabetic Retinopathy

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51QIAGEN, 53Reactome, 29KEGG, 37NCBI BioSystems Database, 12EMD Millipore, 4Cell Signaling Technology
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Pathways related to Proliferative Diabetic Retinopathy according to GeneCards/GeneDecks:

(show all 24)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
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10.5TIMP2, TIMP3, HGF, CCL2, CTGF, ANGPT2
2
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10.5TIMP2, TIMP3, HGF, CCL2, CTGF, ANGPT2
3
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10.5CCL2, VEGFA, SST, CXCL10, CXCL12, VCAM1
4
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10.5TIMP2, TIMP3, HGF, CTGF, ANGPT2, CXCL10
5
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10.5TIMP2, TIMP3, HGF, CCL2, CTGF, ANGPT2
610.5TIMP3, HGF, VEGFA, VTN
7
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10.5HGF, ANGPT2, EPHB4, CXCL10, CXCL12, SERPINF1
8
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10.5TIMP2, TIMP3, HGF, CTGF, CXCL12, VTN
9
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10.5CCL2, CXCL10, CXCL12, VCAM1, VTN
10
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10.5TIMP2, TIMP3, HGF, CTGF, EPHB4, CXCL12
11
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10.5TIMP2, TIMP3, HGF, CTGF, CXCL12
12
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10.5TIMP2, TIMP3, HGF, CTGF, EPHB4, CXCL12
13
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10.5CTGF, HGF, TIMP3
14
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10.5EPHB4, CTGF, HGF, TIMP3
1510.5VEGFA, TIMP3, TIMP2
16
Cell adhesion ECM remodeling
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10.5VTN, TIMP3, TIMP2
1710.5TGFB2, ANGPT2, TIMP3, TIMP2
18
Hide members
10.5TIMP2, HGF, CTGF, EPHB4, CXCL12
1910.5VEGFA, IGFBP1, CXCL12, ADM
2010.5CCL2, CXCL10, CXCL12
21
Hide members
10.5VEGFA
2210.5TIMP3
23
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10.5EPHB4, TIMP3
24
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10.5IGFBP1, CCL2

Compounds for genes affiliated with Proliferative Diabetic Retinopathy

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44Novoseek, 24HMDB, 28IUPHAR, 59Tocris Bioscience, 2BitterDB, 11DrugBank, 49PharmGKB
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Compounds related to Proliferative Diabetic Retinopathy according to GeneCards/GeneDecks:

(show top 50)    (show all 135)
idCompoundScoreTop Affiliating Genes
1vegf4411.0TGFB2, ANGPT2, VEGFA, CTGF, CCL2, HGF
2tyrosine4411.0ANGPT2, VEGFA, GAD1, CTGF, HGF, TIMP3
3retinoic acid44 2412.0TIMP2, TIMP3, PTGDS, CXCL10, MIF, IGFBP1
4genistein44 28 59 2 11 2416.0TGFB2, VCAM1, CXCL12, CXCL10, MIF, IGFBP1
5dexamethasone44 49 28 1114.0TGFB2, VTN, SERPINF1, CXCL12, ANGPT2, VEGFA
6calcium44 49 11 2414.0GAD1, CTGF, CCL2, HGF, TIMP3, TIMP2
7glucose4411.0TIMP2, TIMP3, CTGF, TGFB2, ADM, SERPINF1
8phosphatidylinositol4411.0ANGPT2, CTGF, CCL2, HGF, TIMP3, IGFBP1
9lipid4411.0CTGF, CCL2, HGF, TIMP3, TIMP2, IGFBP1
10heparin44 28 11 2414.0TIMP2, TIMP3, CTGF, VEGFA, CXCL12, VCAM1
11ly2940024411.0TIMP2, TIMP3, HGF, CCL2, CTGF, VEGFA
12oxygen44 2412.0TIMP2, TIMP3, HGF, CCL2, GAD1, ANGPT2
13paraffin4411.0TIMP2, TIMP3, HGF, CCL2, VEGFA, ANGPT2
14cycloheximide4411.0PTGDS, CXCL12, CXCL10, IGFBP1, HGF
15thymidine44 2412.0TIMP2, HGF, CTGF, ANGPT2, IGFBP1, MIF
16cysteine4411.0ANGPT2, GAD1, CTGF, TIMP3, TIMP2, IGFBP1
17creatinine4411.0CXCL10, IGFBP1, ANGPT2, GAD1, TIMP2, PTGDS
18matrigel4411.0CXCL10, TGFB2, VTN, CXCL12
19nitric oxide44 11 2413.0CTGF, ANGPT2, IGFBP1, MIF, CXCL10, VCAM1
20pge24411.0VTN, SST, VEGFA
21wortmannin4410.9TIMP3, HGF, CCL2, ANGPT2, CXCL10, CXCL12
22herbimycin a44 5911.9TIMP2, HGF, CCL2, IGFBP1, MIF, CXCL12
23glycosaminoglycan4410.9TIMP2, TIMP3, CXCL10, CXCL12, SERPINF1, VTN
24cholesterol44 28 11 2413.9TIMP2, CCL2, GAD1, IGFBP1, CXCL10, CXCL12
25lactate4410.9TIMP2, HGF, CTGF, SST, IGFBP1, MIF
26ribonucleic acid4410.9TIMP2, TIMP3, CCL2, CTGF, ANGPT2, IGFBP1
27streptozotocin4410.9GAD1, SST, SERPINF1, ADM
28sb 20358044 5911.9TIMP2, HGF, CCL2, CTGF, VEGFA, MIF
29ccl444 2811.9HGF, CCL2, CXCL10, CXCL12
30hyaluronic acid44 2411.9TIMP2, HGF, VEGFA, CXCL12, VCAM1, VTN
31hydrocortisone44 2 59 1113.9ADM, IGFBP1
32arginine4410.9TIMP3, HGF, CCL2, GAD1, SST, IGFBP1
33fibrinogen4410.8TIMP2, CCL2, CTGF, ANGPT2, IGFBP1, CXCL12
34tamoxifen44 49 28 1113.8IGFBP1, CXCL12, VCAM1, VTN
35pioglitazone44 49 28 1113.8TIMP2, CCL2, CTGF, VEGFA, IGFBP1, VCAM1
36prostacyclin4410.8HGF, CCL2, CTGF, VEGFA, VCAM1, VTN
37losartan44 49 28 1113.8TIMP2, HGF, CCL2, CTGF, VCAM1, ADM
38pd 98,0594410.8TIMP2, TIMP3, HGF, CCL2, CTGF, CXCL12
39serine4410.8TIMP2, CCL2, CTGF, MIF, SERPINF1, VTN
405fluorouracil4410.7TIMP2, HGF, CCL2, VEGFA, SST, CXCL12
41testosterone44 59 11 2413.7TIMP3, HGF, CCL2, SST, IGFBP1, PTGDS
42estradiol44 11 2412.7TIMP3, GAD1, TGFB2
43steroid4410.7TIMP2, TIMP3, GAD1, ANGPT2, IGFBP1, MIF
44n acetylcysteine4410.7HGF, CCL2, CTGF, VEGFA, VCAM1, SERPINF1
45cytochalasin d44 5911.6TIMP2, CCL2, CTGF, CXCL12, VCAM1, VTN
46tgf beta14410.6TIMP3, HGF, CCL2, CTGF, VCAM1, TGFB2
47cyclophosphamide44 49 1112.5HGF, SST, MIF, CXCL12
48glutamate4410.5GAD1
49norepinephrine44 11 2412.4ADM
50histamine44 28 2412.2HGF, CCL2, SST, CXCL10, PTGDS, VCAM1

GO Terms for genes affiliated with Proliferative Diabetic Retinopathy

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16Gene Ontology
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Cellular components related to Proliferative Diabetic Retinopathy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00557610.7TIMP2, ADM, VTN, SERPINF1, PTGDS, CXCL12
2extracellular spaceGO:00561510.7TIMP2, HGF, TGFB2, ADM, VTN, SERPINF1
3cell surfaceGO:00998610.5TIMP2, VEGFA, MIF, EPHB4, VCAM1
4neuronal cell bodyGO:04302510.5TGFB2, SST, CCL2, TIMP2
5extracellular matrixGO:03101210.4TGFB2, VTN, SERPINF1, TIMP3
6platelet alpha granule lumenGO:03109310.2HGF, VEGFA, TGFB2

Biological processes related to Proliferative Diabetic Retinopathy according to GeneCards/GeneDecks:

(show all 20)
idNameGO IDScoreTop Affiliating Genes
1response to hypoxiaGO:00166610.9TGFB2, ADM, VCAM1, ANGPT2, VEGFA, CCL2
2angiogenesisGO:00152510.8CCL2, CTGF, VEGFA, ANGPT2, EPHB4, TGFB2
3organ regenerationGO:03110010.8HGF, CCL2, ANGPT2, ADM
4negative regulation of angiogenesisGO:01652510.8SERPINF1, CXCL10, ANGPT2, CCL2
5positive regulation of peptidyl-tyrosine phosphorylationGO:05073110.8HGF, VEGFA, MIF, VTN
6positive chemotaxisGO:05091810.8MIF, VEGFA, HGF
7agingGO:00756810.8TIMP2, CCL2, VCAM1, ADM
8response to amino acid stimulusGO:04320010.8CCL2, CTGF, SST
9response to drugGO:04249310.8TGFB2, SST, GAD1, CCL2, TIMP2
10heart morphogenesisGO:00300710.7VEGFA, EPHB4, TGFB2
11blood circulationGO:00801510.7ADM, CXCL12, CXCL10
12cell surface receptor signaling pathwayGO:00716610.7CXCL10, MIF, SST, CCL2
13response to woundingGO:00961110.7CTGF, ADM, TGFB2
14positive regulation of cell proliferationGO:00828410.7TGFB2, ADM, CXCL10, VEGFA, CTGF
15cell adhesionGO:00715510.6CCL2, EPHB4, CXCL12, VCAM1, VTN
16response to glucocorticoid stimulusGO:05138410.6ADM, PTGDS, CCL2
17positive regulation of angiogenesisGO:04576610.5ADM, ANGPT2, VEGFA
18cell-cell signalingGO:00726710.5SST, CXCL10, ADM, TGFB2
19platelet degranulationGO:00257610.4HGF, VEGFA, TGFB2
20signal transductionGO:00716510.2CCL2, ANGPT2, IGFBP1, CXCL10, CXCL12, ADM

Molecular functions related to Proliferative Diabetic Retinopathy according to GeneCards/GeneDecks:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1receptor bindingGO:00510210.7TGFB2, ADM, CXCL12, CXCL10, MIF, ANGPT2
2growth factor activityGO:00808310.6HGF, CTGF, VEGFA, CXCL12, TGFB2
3integrin bindingGO:00517810.6TIMP2, CTGF, VCAM1, VTN
4chemoattractant activityGO:04205610.5MIF, VEGFA, HGF
5metalloendopeptidase inhibitor activityGO:00819110.5TIMP3, TIMP2
6heparin bindingGO:00820110.4CCL2, CTGF, VEGFA, VTN
7chemokine activityGO:00800910.2CXCL12, CXCL10, CCL2

Products for genes affiliated with Proliferative Diabetic Retinopathy

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Sources for Proliferative Diabetic Retinopathy

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet