MCID: PRL003
MIFTS: 43

Proliferative Glomerulonephritis malady

Categories: Nephrological diseases

Aliases & Classifications for Proliferative Glomerulonephritis

Aliases & Descriptions for Proliferative Glomerulonephritis:

Name: Proliferative Glomerulonephritis 12 52 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:4778
NCIt 47 C35281
SNOMED-CT 64 441815006
UMLS 69 C0235618

Summaries for Proliferative Glomerulonephritis

MalaCards based summary : Proliferative Glomerulonephritis is related to membranoproliferative glomerulonephritis and rheumatoid arthritis. An important gene associated with Proliferative Glomerulonephritis is CCL2 (C-C Motif Chemokine Ligand 2), and among its related pathways/superpathways are Innate Immune System and Allograft rejection. The drugs Cyclophosphamide and Methylprednisolone have been mentioned in the context of this disorder. Affiliated tissues include kidney, t cells and endothelial, and related phenotypes are Increased shRNA abundance (Z-score > 2) and hematopoietic system

Related Diseases for Proliferative Glomerulonephritis

Diseases in the Proliferative Glomerulonephritis family:

Acute Proliferative Glomerulonephritis

Diseases related to Proliferative Glomerulonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 217)
id Related Disease Score Top Affiliating Genes
1 membranoproliferative glomerulonephritis 29.5 CD79A IL4 IL6
2 rheumatoid arthritis 29.2 CCL2 CD79A IFNG IL4 IL6
3 immune-complex glomerulonephritis 27.7 C3 CCL2 CD79A CFH CR1 CXCR3
4 mesangial proliferative glomerulonephritis 12.4
5 acute proliferative glomerulonephritis 12.4
6 c1q deficiency 11.1
7 glomerulonephritis 10.9
8 malignant renovascular hypertension 10.3 CD79A IFNG
9 generalized atherosclerosis 10.3 CD79A IL6
10 schwannoma of ureter 10.3 CCL2 IL6
11 congenital nystagmus 10.2 C3 CD79A
12 supratentorial primitive neuroectodermal tumor 10.2 CCL2 CD79A IL6
13 lateral cystocele 10.2 CCL2 CD79A IL6
14 metachronous kidney wilms' tumor 10.2 C3 CD79A
15 pediatric meningioma 10.2 CD79A MPO
16 dancing eyes-dancing feet syndrome 10.2 CCL2 MPO
17 mixed mineral dust pneumoconiosis 10.2 CCL2 IFNG IL6
18 desmoplastic small round cell tumor 10.2 C3 CFH
19 chronic mucocutaneous candidiasis 10.2 C3 CD79A
20 stiff-person syndrome 10.2 CCL2 IFNG IL6
21 spastic diplegia 10.2 CD79A IFNG
22 sclerosing adenosis of breast 10.2 CCL2 IFNG IL6
23 rhizomelic chondrodysplasia punctata 10.2 C3 CFH
24 disease of mental health 10.2 CD79A IFNG IL6
25 calcinosis 10.2 CCL2 CD79A IL6
26 follicular adenoma 10.2 CD79A IFNG IL6
27 detrusor sphincter dyssynergia 10.2 CCL2 IFNG IL6
28 pulmonary eosinophilia 10.2 CCL2 IFNG IL6
29 anterior foramen magnum meningioma 10.2 CD79A IFNG IL6
30 anus leiomyosarcoma 10.2 CD79A IFNG IL6
31 vulvar disease 10.2 CD79A MPO
32 dengue disease 10.1 CD79A IFNG IL6
33 angiomatosis, diffuse corticomeningeal, of divry and van bogaert 10.1 IL6 MPO
34 nephrotic syndrome 10.1
35 smooth muscle tumor 10.1 CCL2 CXCR3 IL6
36 uveitis 10.1 CCL2 CD79A MPO
37 malignant oculomotor nerve tumor 10.1 CCL2 CXCR3 IFNG
38 bronchiolitis 10.1 C3 CD79A CFH
39 cyclosporiasis 10.1 CXCR3 IFNG IL6
40 strawberry gallbladder 10.1 CCL2 IFNG MPO
41 uterine adnexa cancer 10.1 C3 CFH IL6
42 macular degeneration, age-related, 13 10.1 C3 CR1
43 retinal ischemia 10.1 CCL2 CXCR3 IFNG
44 venezuelan hemorrhagic fever 10.1 CD79A CXCR3 IFNG
45 causalgia 10.1 CXCR3 IFNG IL6
46 chronic progressive external ophthalmoplegia 10.1 C3 CD79A CFH
47 myoglobinuria recurrent 10.1 IFNG IL4
48 burns 10.1 CXCR3 IFNG IL6
49 cyclotropia 10.1 C3 CD79A MPO
50 eating disorder 10.1 CCL2 CD79A MPO

Graphical network of the top 20 diseases related to Proliferative Glomerulonephritis:



Diseases related to Proliferative Glomerulonephritis

Symptoms & Phenotypes for Proliferative Glomerulonephritis

GenomeRNAi Phenotypes related to Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-100 9.62 MPO
2 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.62 IL4
3 Increased shRNA abundance (Z-score > 2) GR00366-A-11 9.62 CD79A
4 Increased shRNA abundance (Z-score > 2) GR00366-A-126 9.62 MPO
5 Increased shRNA abundance (Z-score > 2) GR00366-A-157 9.62 MPO
6 Increased shRNA abundance (Z-score > 2) GR00366-A-176 9.62 MPO
7 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.62 CD79A
8 Increased shRNA abundance (Z-score > 2) GR00366-A-185 9.62 IL4
9 Increased shRNA abundance (Z-score > 2) GR00366-A-186 9.62 MPO
10 Increased shRNA abundance (Z-score > 2) GR00366-A-22 9.62 IL4
11 Increased shRNA abundance (Z-score > 2) GR00366-A-29 9.62 MPO
12 Increased shRNA abundance (Z-score > 2) GR00366-A-36 9.62 MPO
13 Increased shRNA abundance (Z-score > 2) GR00366-A-42 9.62 IL4
14 Increased shRNA abundance (Z-score > 2) GR00366-A-57 9.62 MPO
15 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.62 CD79A
16 Increased shRNA abundance (Z-score > 2) GR00366-A-7 9.62 MPO
17 Increased shRNA abundance (Z-score > 2) GR00366-A-70 9.62 CD79A IL4 MPO
18 Increased shRNA abundance (Z-score > 2) GR00366-A-74 9.62 CD79A

MGI Mouse Phenotypes related to Proliferative Glomerulonephritis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.91 IFNG IL4 IL6 MPO C3 SIGLEC1
2 homeostasis/metabolism MP:0005376 9.81 CXCR3 IFNG IL4 IL6 MPO C3
3 immune system MP:0005387 9.65 IFNG IL4 IL6 C3 MPO SIGLEC1
4 renal/urinary system MP:0005367 9.17 IFNG IL4 IL6 C3 CD79A CFH

Drugs & Therapeutics for Proliferative Glomerulonephritis

Drugs for Proliferative Glomerulonephritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 77)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cyclophosphamide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 50-18-0, 6055-19-2 2907
2
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 83-43-2 6741
3
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-24-8 5755
4
Azathioprine Approved Phase 4,Phase 3,Phase 1 446-86-6 2265
5
Benzocaine Approved Phase 4,Phase 3 1994-09-7, 94-09-7 2337
6
Mycophenolate mofetil Approved, Investigational Phase 4,Phase 3,Phase 2 128794-94-5 5281078
7
Mycophenolic acid Approved Phase 4,Phase 3,Phase 2 24280-93-1 446541
8
Enalapril Approved, Vet_approved Phase 4 75847-73-3 5362032 40466924
9
Enalaprilat Approved Phase 4 76420-72-9 6917719
10
rituximab Approved Phase 4,Phase 3 174722-31-7 10201696
11
Calcitriol Approved, Nutraceutical Phase 4 32222-06-3 134070 5280453
12 tannic acid Approved, Nutraceutical Phase 4,Phase 3
13 Antibodies Phase 4,Phase 3,Phase 2,Phase 1
14 Bone Density Conservation Agents Phase 4,Phase 3
15 Calcium, Dietary Phase 4
16 Immunoglobulin A Phase 4,Phase 3
17 Immunoglobulins Phase 4,Phase 3,Phase 2,Phase 1
18 Micronutrients Phase 4,Phase 3
19 Trace Elements Phase 4,Phase 3
20 Vasoconstrictor Agents Phase 4
21 Vitamins Phase 4,Phase 3
22 Alkylating Agents Phase 4,Phase 3,Phase 2,Phase 1
23 Antineoplastic Agents, Alkylating Phase 4,Phase 3,Phase 2,Phase 1
24 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Phase 1
25 Immunosuppressive Agents Phase 4,Phase 3,Phase 2,Phase 1
26 Methylprednisolone acetate Phase 4,Phase 3,Phase 2
27 Methylprednisolone Hemisuccinate Phase 4,Phase 3,Phase 2
28 Prednisolone acetate Phase 4,Phase 3,Phase 2
29 Prednisolone hemisuccinate Phase 4,Phase 3,Phase 2
30 Prednisolone phosphate Phase 4,Phase 3,Phase 2
31 Antiemetics Phase 4,Phase 3,Phase 2
32 Anti-Inflammatory Agents Phase 4,Phase 2,Phase 3,Phase 1
33 Antimetabolites Phase 4,Phase 3,Phase 1
34 Antimetabolites, Antineoplastic Phase 4,Phase 3,Phase 1
35 Antineoplastic Agents, Hormonal Phase 4,Phase 2,Phase 3,Phase 1
36 Autonomic Agents Phase 4,Phase 3,Phase 2
37 Gastrointestinal Agents Phase 4,Phase 3,Phase 2
38 glucocorticoids Phase 4,Phase 2,Phase 3,Phase 1
39 Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1
40 Hormones Phase 4,Phase 2,Phase 3,Phase 1
41 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1
42 Neuroprotective Agents Phase 4,Phase 3,Phase 2
43 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
44 Protective Agents Phase 4,Phase 3,Phase 2
45 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2
46 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2
47 Adrenocorticotropic Hormone Phase 4
48 beta-endorphin Phase 4
49 Melanocyte-Stimulating Hormones Phase 4
50 Angiotensin-Converting Enzyme Inhibitors Phase 4,Phase 2

Interventional clinical trials:

(show all 33)
id Name Status NCT ID Phase
1 Calcitriol in the Treatment of Immunoglobulin A Nephropathy Unknown status NCT00862693 Phase 4
2 Calcitriol in the Treatment of Immunoglobulin A (IgA) Nephropathy Completed NCT00319761 Phase 4
3 Comparison of Low Dose Versus High Dose Cyclophosphamide as Induction Therapy in the Treatment of Lupus Nephritis Completed NCT02645565 Phase 4
4 ACTHAR GEL in Patients With Membranous (Class V) Lupus Nephritis Recruiting NCT01926054 Phase 4
5 Rituximab in Recurrent IgA Nephropathy Recruiting NCT02571842 Phase 4
6 ACTHar in the Treatment of Lupus Nephritis Recruiting NCT02226341 Phase 4
7 Velcade for Proliferative Lupus Nephritis Withdrawn NCT01169857 Phase 4
8 Mycophenolate Mofetil Versus Azathioprine for Maintenance Therapy of Lupus Nephritis. Completed NCT00204022 Phase 3
9 Induction Treatment of Proliferative Lupus Nephritis With Leflunomide Combined With Prednisone Completed NCT00268567 Phase 2, Phase 3
10 Concentration-controlled Therapy of Mycophenolate Mofetil (MMF) in Proliferative Lupus Nephritis Completed NCT01042457 Phase 3
11 Trial of Rituximab and Mycophenolate Mofetil Without Oral Steroids for Lupus Nephritis Suspended NCT01773616 Phase 3
12 Efficacy and Safety Study of Abatacept to Treat Lupus Nephritis Terminated NCT00430677 Phase 2, Phase 3
13 The Efficacy of Enteric-coated Mycophenolate Sodium (EC-MPS) (Myfortic) in The Treatment of Relapse or Resistant Proliferative Lupus Nephritis Terminated NCT01015456 Phase 3
14 Paricalcitol for the Treatment of Immunoglobulin A Nephropathy Withdrawn NCT00599963 Phase 3
15 Steroids in the Maintenance of Remission of Proliferative Lupus Nephritis Withdrawn NCT00539799 Phase 3
16 A Pilot Study for the Efficacy and Safety of Tacrolimus in the Treatment of Refractory Lupus Nephritis Unknown status NCT00569101 Phase 2
17 Phase 2 Study of Human Umbilical Cord Derived Mesenchymal Stem Cell for the Treatment of Lupus Nephritis Unknown status NCT01539902 Phase 2
18 BG9588 (Anti-CD40L Antibody) to Treat Lupus Nephritis Completed NCT00001789 Phase 2
19 Cyclosporine A or Intravenous Cyclophosphamide for Lupus Nephritis: The Cyclofa-Lune Study Completed NCT00976300 Phase 2
20 Retinoids for Minimal Change Disease and Focal Segmental Glomerulosclerosis Completed NCT00098020 Phase 1, Phase 2
21 ACE-inhibitors in Extracapillary Glomerulonephritis Recruiting NCT02682459 Phase 2
22 Safety and Efficacy of Two Doses of Anifrolumab Compared to Placebo in Adult Subjects With Active Proliferative Lupus Nephritis Recruiting NCT02547922 Phase 2
23 A Study to Evaluate the Safety and Efficacy of Obinutuzumab Compared With Placebo in Participants With Lupus Nephritis (LN) Recruiting NCT02550652 Phase 2
24 Daratumumab in Treatment of PGNIMD and C3 GN Not yet recruiting NCT03095118 Phase 2
25 Cyclophosphamide and Fludarabine to Treat Lupus Nephritis Completed NCT00001676 Phase 1
26 Tacrolimus Versus Cyclophosphamide as Treatment for Lupus Nephritis Completed NCT01207297 Phase 1
27 An Multi-site Prospective Study to Assess the Efficacy and Safety of MMF in the Treatment of Proliferative IgA Nephropathy(IgAN) Completed NCT01269021
28 Lupus Nephritis: Role of Environmental and Occupational Exposures Completed NCT00342329
29 Leflunomide Versus Azathioprine for Maintenance Therapy of Lupus Nephritis Recruiting NCT01172002
30 Tonsillectomy and Primitive IgA Nephropathy in Children: Strasbourg Cohort and Assessment Practices in Inter North East Region Recruiting NCT02829164
31 Interest to Perform a Renal Biopsy Early in the Course of the Henoch-Schoenlein Nephritis Recruiting NCT02811770
32 The Effect of Mycophenolate Mofetil and Cyclophosphamide on the Lymphocyte Subsets in Patients With Proliferative Lupus Nephritis Recruiting NCT02954939
33 Lupus Flares and Histological Renal Activity at the End of the Treatment (LuFla) Active, not recruiting NCT02313974

Search NIH Clinical Center for Proliferative Glomerulonephritis

Genetic Tests for Proliferative Glomerulonephritis

Anatomical Context for Proliferative Glomerulonephritis

MalaCards organs/tissues related to Proliferative Glomerulonephritis:

39
Kidney, T Cells, Endothelial, B Cells, Lung, Neutrophil, Monocytes

Publications for Proliferative Glomerulonephritis

Articles related to Proliferative Glomerulonephritis:

(show top 50) (show all 389)
id Title Authors Year
1
Mesangial proliferative glomerulonephritis in murine malaria parasite, Plasmodium chabaudi AS, infected NC mice. ( 27815652 )
2016
2
De Novo Proliferative Glomerulonephritis with Monoclonal IgG Deposits of the IgG1I_ Subtype in a Kidney Allograft. ( 26976360 )
2016
3
Immune Complex-Mediated Proliferative Glomerulonephritis Induced by Paclitaxel Treatment. ( 27845869 )
2016
4
Early recurrence of proliferative glomerulonephritis with monoclonal immunoglobulin deposits in a renal allograft. ( 26997395 )
2016
5
C3 mesangial proliferative glomerulonephritis initially presenting with atypical hemolytic uremic syndrome: a case report. ( 27460033 )
2016
6
Proliferative Glomerulonephritis With Monoclonal IgG1I_ Deposits in a Hepatitis C Virus-Positive Patient. ( 26612277 )
2016
7
Th1, Th2 and Treg/T17 cytokines in two types of proliferative glomerulonephritis. ( 27194829 )
2016
8
AJKD Atlas of Renal Pathology: Proliferative Glomerulonephritis With Monoclonal Immunoglobulin Deposits. ( 26916379 )
2016
9
Pityriasis rubra pilaris and mesangial proliferative glomerulonephritis in a child: Association or coincidence? ( 26937085 )
2016
10
Proliferative glomerulonephritis with monoclonal immunoglobulin G deposits complicated by immunoglobulin A nephropathy in the renal allograft. ( 26971743 )
2016
11
Correlation of disease activity in proliferative glomerulonephritis with glomerular spleen tyrosine kinase expression. ( 25715120 )
2015
12
Volatile Organic Metabolites Identify Patients with Mesangial Proliferative Glomerulonephritis, IgA Nephropathy and Normal Controls. ( 26443483 )
2015
13
Multicentric Castleman's disease with renal amyloidosis and mesangial proliferative glomerulonephritis: a case report. ( 25932265 )
2015
14
Diffuse mesangial and endocapillary cell proliferative glomerulonephritis with persistent hypocomplementemia in a child. ( 26629229 )
2015
15
Post-Legionellosis Proliferative Glomerulonephritis. ( 26648502 )
2015
16
Significance of CD163-Positive Macrophages in Proliferative Glomerulonephritis. ( 26379042 )
2015
17
Proliferative glomerulonephritis with monoclonal immunoglobulin deposition disease: The utility of routine staining with immunoglobulin light chains. ( 26664209 )
2015
18
Proliferative glomerulonephritis with monoclonal immunoglobulin in renal allografts. ( 26613031 )
2015
19
Glomerular Damage in Experimental Proliferative Glomerulonephritis Under Glomerular Capillary Hypertension. ( 25871528 )
2015
20
Hydrogen peroxide-inducible clone-5 regulates mesangial cell proliferation in proliferative glomerulonephritis in mice. ( 25835392 )
2015
21
Hepatitis C virus-related mixed cryoglobulinemic endocapillary proliferative glomerulonephritis and B-cell non-Hodgkin lymphoma: a case report and literature review. ( 26367728 )
2015
22
A case of endocapillary proliferative glomerulonephritis with macrophages phagocytosing monoclonal immunoglobulin lambda light chain. ( 25410550 )
2015
23
Proliferative glomerulonephritis associated with monoclonal immune deposits: A case report and review of literature. ( 25484532 )
2014
24
Proliferative glomerulonephritis with monoclonal immunoglobulin A light-chain deposits in the renal allograft. ( 24842824 )
2014
25
Nephrotic syndrome secondary to proliferative glomerulonephritis with monoclonal immunoglobulin deposits of lambda light chain. ( 25136462 )
2014
26
Diffuse segmental and pure diffuse global proliferative glomerulonephritis: different patterns of class IV lupus nephritis. ( 25017669 )
2014
27
Proliferative Glomerulonephritis Due to Monoclonal Deposition With Organized Substructures. ( 25308093 )
2014
28
Recurrent Proliferative Glomerulonephritis With Monoclonal IgG Deposits After a Renal Transplant Which Was Insensitive to Pulse Therapy Remitted by Double Filtration Plasmapheresis. ( 25275829 )
2014
29
Mesangial proliferative glomerulonephritis with acute tubule interstitial nephritis leading to acute kidney injury in influenza A (H1N1) infection. ( 24701045 )
2014
30
Urinary neopterin: an immune activation marker in mesangial proliferative glomerulonephritis. ( 24858931 )
2014
31
Immune profile of IgA-dominant diffuse proliferative glomerulonephritis. ( 25878780 )
2014
32
Goodpasture's syndrome with concomitant immune complex mixed membranous and proliferative glomerulonephritis. ( 23320965 )
2013
33
Monoclonal gammopathy-associated proliferative glomerulonephritis. ( 24182705 )
2013
34
Association of human leukocyte antigen gene polymorphism and mesangial proliferative glomerulonephritis in a large population-based study. ( 24649023 )
2013
35
Proliferative glomerulonephritis causing acute renal failure in a child with Salmonella septicemia. ( 23814433 )
2013
36
A rare case of juvenile acute non-proliferative glomerulonephritis with a 6-year follow-up experience. ( 22297470 )
2013
37
Diffuse proliferative glomerulonephritis associated with cetuximab, an epidermal growth factor receptor inhibitor. ( 23474009 )
2013
38
Monoclonal gammopathy-associated pauci-immune extracapillary-proliferative glomerulonephritis successfully treated with bortezomib. ( 24282629 )
2013
39
Etiology-Based Diagnostic Approach to Proliferative Glomerulonephritis. ( 24387793 )
2013
40
Proliferative glomerulonephritis with discrete deposition of monoclonal immunoglobulin I^1 CH 2 heavy chain and I_ light chain: a new variant of monoclonal immunoglobulin deposition disease. ( 23356227 )
2013
41
Mesangial proliferative glomerulonephritis in familial Mediterranean fever patient with E148Q mutation: the first case report. ( 22261745 )
2013
42
Close relations between podocyte injuries and membranous proliferative glomerulonephritis in autoimmune murine models. ( 23817053 )
2013
43
Transition from endocapillary proliferative glomerulonephritis to membranoproliferative glomerulonephritis in a patient with a prolonged human parvovirus B19 infection. ( 23442257 )
2013
44
A case of adult periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome associated with endocapillary proliferative glomerulonephritis. ( 20225048 )
2013
45
Efficacy of antisense monocyte chemoattractant protein-1 (MCP-1) in a rat model of mesangial proliferative glomerulonephritis. ( 23991758 )
2013
46
Relapsing proliferative glomerulonephritis with monoclonal IgG deposits showing circumferential crescentic glomerulonephritis. ( 26069833 )
2013
47
Recurrent proliferative glomerulonephritis with monoclonal IgG deposits of IgG2I> subtype in a transplanted kidney: a case report. ( 23474011 )
2013
48
Differential proteomic analysis of renal tissue in mesangial proliferative glomerulonephritis using iTRAQ technology. ( 22641580 )
2013
49
Proliferative glomerulonephritis with monoclonal IgG deposits in a patient with autoimmune hemolytic anemia. ( 23725649 )
2013
50
Proliferative Glomerulonephritis With Monoclonal Immunoglobulin Deposits in a Kidney Allograft. ( 24051081 )
2013

Variations for Proliferative Glomerulonephritis

Expression for Proliferative Glomerulonephritis

Search GEO for disease gene expression data for Proliferative Glomerulonephritis.

Pathways for Proliferative Glomerulonephritis

Pathways related to Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

(show all 36)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.55 C3 CCL2 CD79A CFH CR1 IFNG
2
Show member pathways
12.7 C3 IFNG IL4 IL6
3
Show member pathways
12.6 C3 CCL2 IFNG IL4 IL6
4
Show member pathways
12.44 CCL2 IFNG IL6 MPO
5 12.22 CCL2 CD79A IFNG IL4 MPO
6
Show member pathways
12.17 CCL2 IFNG IL4 IL6
7
Show member pathways
12.07 IFNG IL4 IL6
8
Show member pathways
12.05 C3 CR1 IFNG IL4
9
Show member pathways
12.04 IFNG IL4 IL6
10
Show member pathways
12.02 IFNG IL4 IL6
11 12.01 C3 CR1 IFNG IL6
12
Show member pathways
11.98 C3 CFH CR1
13 11.96 C3 CFH CR1
14
Show member pathways
11.94 C3 CFH CR1
15
Show member pathways
11.89 CCL2 IFNG IL4 IL6 MPO
16 11.85 CCL2 IL4 IL6
17
Show member pathways
11.81 C3 CFH CR1
18
Show member pathways
11.78 IFNG IL4 IL6
19 11.75 CR1 IL4 IL6
20 11.75 CCL2 IFNG IL4 IL6
21 11.71 CCL2 IFNG IL6
22 11.67 IFNG IL4 IL6
23 11.65 CXCR3 IFNG IL4
24 11.58 CR1 IL4 IL6
25 11.52 CCL2 IL4 IL6
26 11.44 C3 CR1 IL6
27 11.36 CCL2 IL4 IL6
28 11.11 IFNG IL4 IL6
29 11.09 CD79A IFNG IL4 IL6 MPO
30 11.08 CCL2 IL4 IL6
31 11.08 IFNG IL4
32 11.06 IFNG IL4 IL6
33 11.05 CCL2 IFNG
34 10.95 CCL2 CR1 IFNG IL6
35 10.83 CCL2 MPO
36 10.8 IL4 IL6

GO Terms for Proliferative Glomerulonephritis

Cellular components related to Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.76 C3 CCL2 CFH IFNG IL4 IL6
2 extracellular space GO:0005615 9.5 C3 CCL2 CFH IFNG IL4 IL6
3 external side of plasma membrane GO:0009897 9.02 CD79A CXCR3 IFNG IL4 IL6

Biological processes related to Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

(show all 24)
id Name GO ID Score Top Affiliating Genes
1 response to drug GO:0042493 9.86 CCL2 IFNG IL4 IL6
2 cell surface receptor signaling pathway GO:0007166 9.8 CCL2 CD79A CXCR3 IFNG
3 aging GO:0007568 9.79 CCL2 IL6 MPO
4 chemotaxis GO:0006935 9.79 CCL2 CXCR3 IL4
5 positive regulation of protein phosphorylation GO:0001934 9.78 C3 IFNG IL4
6 cellular response to lipopolysaccharide GO:0071222 9.77 CCL2 IFNG IL6
7 regulation of complement activation GO:0030449 9.75 C3 CFH CR1
8 immune response GO:0006955 9.72 C3 CCL2 IFNG IL4 IL6
9 response to mechanical stimulus GO:0009612 9.63 CCL2 IL6 MPO
10 positive regulation of T cell proliferation GO:0042102 9.61 IFNG IL4 IL6
11 negative regulation of growth of symbiont in host GO:0044130 9.6 IFNG MPO
12 complement activation, alternative pathway GO:0006957 9.58 C3 CFH
13 positive regulation of protein import into nucleus, translocation GO:0033160 9.57 IFNG IL6
14 positive regulation of chemokine biosynthetic process GO:0045080 9.55 IFNG IL4
15 positive regulation of isotype switching to IgG isotypes GO:0048304 9.54 IFNG IL4
16 humoral immune response GO:0006959 9.54 CCL2 IFNG IL6
17 positive regulation of MHC class II biosynthetic process GO:0045348 9.52 IFNG IL4
18 positive regulation of apoptotic cell clearance GO:2000427 9.51 C3 CCL2
19 response to yeast GO:0001878 9.48 IL6 MPO
20 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.43 IFNG IL4 IL6
21 regulation of vascular endothelial growth factor production GO:0010574 9.4 CCL2 IL6
22 inflammatory response GO:0006954 9.35 C3 CCL2 CXCR3 IL6 SIGLEC1
23 neutrophil apoptotic process GO:0001781 9.16 IFNG IL6
24 defense response to protozoan GO:0042832 8.8 IFNG IL4 IL6

Molecular functions related to Proliferative Glomerulonephritis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 heparin binding GO:0008201 9.13 CCL2 CFH MPO
2 cytokine activity GO:0005125 8.92 CCL2 IFNG IL4 IL6

Sources for Proliferative Glomerulonephritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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