MCID: PRS039
MIFTS: 48

Prostate Adenocarcinoma malady

Summaries for Prostate Adenocarcinoma

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63Wikipedia, 32MalaCards
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Wikipedia:63 Prostate cancer is a form of cancer that develops in the prostate, a gland in the male reproductive... more...

MalaCards: Prostate Adenocarcinoma, also known as adenocarcinoma of prostate, is related to adenocarcinoma and prostatitis. An important gene associated with Prostate Adenocarcinoma is CTNND2 (catenin (cadherin-associated protein), delta 2). The compounds tyrosine and paraffin have been mentioned in the context of this disorder. Affiliated tissues include prostate, bone and lymph node.

Aliases & Classifications for Prostate Adenocarcinoma

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Sources:
8Disease Ontology, 46OMIM, 60UMLS, 39NCIt, 56SNOMED-CT
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Aliases & Descriptions:

prostate adenocarcinoma 8 46
adenocarcinoma of prostate 8 60


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Disease Ontology8 DOID:2526
SNOMED-CT56 399490008
NCIt39 C2919

Related Diseases for Prostate Adenocarcinoma

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17GeneCards, 18GeneDecks
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Diseases related to Prostate Adenocarcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 151)
idRelated DiseaseScoreTop Affiliating Genes
1adenocarcinoma32.1KLK3, IBSP, AMACR, IFI27, ALOX15B, CEACAM3
2prostatitis32.1ACPP, KLK3
3prostate cancer30.8ACPP, KLK3
4prostate disease30.6ACPP, FOLH1, AMACR, KLK3
5bladder adenocarcinoma30.6KLK3, KRT7, KRT20
6adenoma30.5AMACR, IFI27, CHGA, CLDN3, KRT7, KRT20
7lung adenocarcinoma30.5AMACR, KRT7, KRT20, CEACAM3
8bladder carcinoma30.5KRT20
9prostatic adenoma30.5ACPP, KLK3
10nephrogenic adenoma30.5KRT7, AMACR
11transitional cell carcinoma30.3KLK3, IFI27, FOLH1, KRT7, KRT20, ENO2
12squamous cell carcinoma30.2CHGA, CSTA, IFI27, AMACR, IBSP, CLDN3
13lung small cell carcinoma30.2KLK3, AMACR, CHGA, KRT7, KRT20, ACPP
14gastric adenocarcinoma30.2CHGA, CLDN3, KRT7, KRT20
15cervical adenocarcinoma30.2KRT20, KRT7, IFI27
16papilloma30.2IFI27, KRT20
17signet ring cell adenocarcinoma30.0CHGA, KRT7, KRT20
18lung cancer29.9IBSP, AMACR, IFI27, CSTA, CHGA, MSMB
19tubular adenocarcinoma29.9CHGA, KRT7, KRT20, ENO2
20neuroendocrine carcinoma29.9CHGA, KRT7, KRT20, ENO2
21non-small cell lung carcinoma29.9IBSP, IFI27, CSTA, CHGA, ENO2
22cystadenoma29.9CEACAM3, KRT7
23melanoma29.9IBSP, AMACR, IFI27, FOLH1, ENO2, CEACAM3
24colon adenocarcinoma29.9KRT20
25sertoli cell tumor29.9ENO2
26bladder transitional cell carcinoma29.9KRT20, IFI27
27adenocarcinoma in situ10.3
28breast adenocarcinoma10.3
29papillary adenocarcinoma10.3
30seminal vesicle adenocarcinoma10.3
31prostate small cell carcinoma10.3
32lymphoepithelioma-like acinar prostate adenocarcinoma10.3
33small cell carcinoma10.3
34choroiditis10.2
35prostate transitional cell carcinoma10.2
36myeloma10.2
37retinoblastoma10.2
38urethra adenocarcinoma10.2
39cushing's syndrome10.1
40priapism10.1
41nephrogenic adenoma of the urethra10.1
42prostate squamous cell carcinoma10.1
43prostatic acinar adenocarcinoma10.1
44cervicitis10.1
45herpes simplex10.1
46liposarcoma10.1
47lung squamous cell carcinoma10.1
48meningioma10.1
49multiple myeloma10.1
50rectum adenocarcinoma10.1

Graphical network of the top 20 diseases related to Prostate Adenocarcinoma:



Diseases related to prostate adenocarcinoma

Clinical Features for Prostate Adenocarcinoma

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Drugs & Therapeutics for Prostate Adenocarcinoma

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

Search ClinicalTrials for Prostate Adenocarcinoma

Search NIH Clinical Center for Prostate Adenocarcinoma

Search CenterWatch for Prostate Adenocarcinoma

Genetic Tests for Prostate Adenocarcinoma

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Anatomical Context for Prostate Adenocarcinoma

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32MalaCards
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MalaCards organs/tissues related to Prostate Adenocarcinoma:

32
Prostate, Bone, Lymph node, Lung, Endothelial, Breast, Skin, Spinal cord, Colon, Brain, Pituitary, Bone marrow, Liver, Monocytes, T cells, B cells, Myeloid, Testis, Testes, Thyroid, Kidney, Cervix

Animal Models for Prostate Adenocarcinoma or affiliated genes

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Publications for Prostate Adenocarcinoma

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Sources:
50PubMed
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Articles related to Prostate Adenocarcinoma:

(show top 50)    (show all 917)
idTitleAuthorsYear
1
Salvage external beam radiotherapy for recurrent prostate adenocarcinoma after high-intensity focused ultrasound as primary treatment. (23364287)
2013
2
The ejaculatory ducts and their implications in prostate adenocarcinoma. (24341123)
2013
3
Prostate-specific antigen kinetics after I125-brachytherapy for prostate adenocarcinoma. (22922810)
2013
4
Loss of survivin in the prostate epithelium impedes carcinogenesis in a mouse model of prostate adenocarcinoma. (23936028)
2013
5
A presentation of glandular penile metastases from prostate adenocarcinoma. (22486259)
2012
6
Hypertrophic gastric folds caused by metastatic prostate adenocarcinoma. (22396273)
2012
7
Protease nexin 1 inhibits hedgehog signaling in prostate adenocarcinoma. (23041623)
2012
8
Is there a role for prostate tumour overexpressed-1 in the diagnosis of HGPIN and of prostatic adenocarcinoma? A comparison with alpha-methylacyl CoA racemase. (22507319)
2012
9
Inter/intra-observer reproducibility of Gleason scoring in prostate adenocarcinoma in Iranian pathologists. (22641492)
2012
10
Multifaceted preventive effects of single agent quercetin on a human prostate adenocarcinoma cell line (PC-3): implications for nutritional transcriptomics and multi-target therapy. (20596804)
2011
11
Can telomere alterations predict biochemical recurrence in prostate adenocarcinoma? A preliminary study. (20674190)
2010
12
Multiple cranial neuropathy as the initial presentation of metastatic prostate adenocarcinoma: case report and review of literature. (20379748)
2010
13
Clinicopathological behavior of single focus prostate adenocarcinoma. (19836800)
2009
14
TMPRSS2-ERG gene fusions are infrequent in prostatic ductal adenocarcinomas. (19151660)
2009
15
CASPASE-3 and CD-34 expression in prostate adenocarcinoma. (20076902)
2009
16
Gene expression profiles of ductal versus acinar adenocarcinoma of the prostate. (19633648)
2009
17
Induction of apoptosis in the LNCaP human prostate carcinoma cell line and prostate adenocarcinomas of SV40T antigen transgenic rats by the Bowman-Birk inhibitor. (19883429)
2009
18
Elevation of total PSA after intravesical BCG instillations: granulomatous prostatitis or prostatic adenocarcinoma?]. (18396238)
2008
19
BRAF activation initiates but does not maintain invasive prostate adenocarcinoma. (19079609)
2008
20
Immunohistochemical expression of prostatic antigens in adenocarcinoma and villous adenoma of the urinary bladder. (18670358)
2008
21
Epidermal growth factor receptor (EGFR) expression in prostatic adenocarcinoma after hormonal therapy: a fluorescence in situ hybridization and immunohistochemical analysis. (18409189)
2008
22
Diagnosis of adenocarcinoma in prostate needle biopsy tissue. (17213347)
2007
23
Antitumor effect of endothelial monocyte-activating polypeptide-II on human prostate adenocarcinoma in mouse xenograft model. (18199981)
2007
24
Immunohistochemical antibody cocktail staining (p63/HMWCK/AMACR) of ductal adenocarcinoma and Gleason pattern 4 cribriform and noncribriform acinar adenocarcinomas of the prostate. (17527076)
2007
25
Improved biochemical relapse-free survival for patients with large/wide glands treated with prostate seed implantation for localized adenocarcinoma of prostate. (17169646)
2006
26
To what extent does the prostate-specific antigen nadir predict subsequent treatment failure after transrectal high-intensity focused ultrasound therapy for presumed localized adenocarcinoma of the prostate? (16925749)
2006
27
Metastasis of prostatic adenocarcinoma to the sphenoid sinus. (17044541)
2006
28
Optimal use of a panel of methylation markers with GSTP1 hypermethylation in the diagnosis of prostate adenocarcinoma. (15328191)
2004
29
Chylous ascites from prostatic adenocarcinoma. (11992926)
2002
30
Cystic solitary intracerebral metastasis from prostate adenocarcinoma. (11326565)
2001
31
Coordinate expression of cytokeratins 7 and 20 in prostate adenocarcinoma and bladder urothelial carcinoma. (10705819)
2000
32
Whole genome amplification and molecular genetic analysis of DNA from paraffin-embedded prostate adenocarcinoma tumor tissue. (10492247)
1999
33
Sarcomatoid carcinoma of the prostate: progression from adenocarcinoma is associated with p53 over-expression. (10628387)
1999
34
5-fluorouracil and low-dose recombinant interferon-alpha-2a in patients with hormone-refractory adenocarcinoma of the prostate. (9537600)
1998
35
Cell proliferation rate by MIB-1 immunohistochemistry predicts postradiation recurrence in prostatic adenocarcinomas. (9583887)
1998
36
Retinoids stimulate lipid synthesis and accumulation in LNCaP prostatic adenocarcinoma cells. (9510066)
1997
37
The role of prostate specific antigen in diagnosis of localized adenocarcinoma of the prostate. Nara Uro-Oncology Research Group]. (8951478)
1996
38
Characterisation of platelet aggregation induced by PC-3 human prostate adenocarcinoma cells and inhibited by venom peptides, trigramin and rhodostomin. (8695278)
1996
39
Effect of microwave oven heating times on androgen receptor antigen retrieval from paraffin-embedded prostatic adenocarcinoma. (8917409)
1996
40
Genomic methylation patterns of the Dunning R-3327 prostate adenocarcinoma system. (8556711)
1996
41
Ploidy status correlates with outcome in stage B prostate adenocarcinoma. (8173528)
1994
42
A case of prostatic adenocarcinoma with pulmonary metastases--diagnosis by transbronchial lung biopsy and immunohistochemistry]. (7531254)
1994
43
IGF binding protein-3 secreted by the prostate adenocarcinoma cells (PC-3): differential effect on PC-3 and normal prostate cell growth. (7693099)
1993
44
Comparison of DNA content in primary and lymph node metastases in prostate adenocarcinoma. (8347255)
1993
45
Nephrogenic adenomas of the urethra involving the prostate gland: a report of two cases of a lesion that may be confused with prostatic adenocarcinoma. (1369796)
1992
46
Monoclonal antibody PD41 recognizes an antigen restricted to prostate adenocarcinomas. (1705172)
1991
47
Mitogenic effects of insulin and insulin-like growth factors on PA-III rat prostate adenocarcinoma cells: characterization of the receptors involved. (1661415)
1991
48
Serum prolactin levels in patients treated with a gonadotropin-releasing hormone analogue for adenocarcinoma of the prostate. (1901042)
1991
49
Mucinous adenocarcinoma of the prostate: histochemical and immunohistochemical studies. (1693591)
1990
50
Mucinous adenocarcinoma of the prostate. (2426179)
1986

Genetic Variations for Prostate Adenocarcinoma

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Expression for genes affiliated with Prostate Adenocarcinoma

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Prostate Adenocarcinoma

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Pathways for genes affiliated with Prostate Adenocarcinoma

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Compounds for genes affiliated with Prostate Adenocarcinoma

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Sources:
44Novoseek, 49PharmGKB, 11DrugBank, 24HMDB, 59Tocris Bioscience, 28IUPHAR
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Compounds related to Prostate Adenocarcinoma according to GeneCards/GeneDecks:

(show top 50)    (show all 58)
idCompoundScoreTop Affiliating Genes
1tyrosine4411.9IBSP, AMACR, IFI27, CSTA, CTNND2, CHGA
2paraffin4411.8ALOX15B, KLK3, IBSP, CEACAM3, ENO2, ACPP
3vegf4411.8KLK3, IBSP, IFI27, FOLH1, CHGA, CLDN3
4calcium44 49 11 2414.8RLN1, IBSP, AMACR, IFI27, BMP3, CHGA
5testosterone44 59 11 2414.7FOLH1, IFI27, AMACR, KLK3, CHGA, KRT7
6hematoxylin4411.6CEACAM3, ENO2, ACPP, KRT20, KRT7, CHGA
7steroid4411.6KLK3, IBSP, IFI27, CHGA, ACPP, MSMB
8progesterone44 59 28 11 2415.5AMACR, IFI27, CHGA, KRT7, KRT20, ACPP
9vitamin d4411.4ACPP, CHGA, IFI27, AMACR, IBSP, KLK3
10dexamethasone44 49 28 1114.4KLK3, IBSP, AMACR, IFI27, BMP3, ENO2
11lactate4411.4KLK3, IFI27, CHGA, ACPP, ENO2, CEACAM3
12thymidine44 2412.3IBSP, IFI27, FOLH1, ACPP, ENO2, CEACAM3
13streptavidin4411.3AMACR, FOLH1, KRT7, KRT20, CEACAM3
14formaldehyde44 2412.3KLK3, CHGA, KRT7, KRT20, ENO2
15cholesterol44 28 11 2414.3AMACR, CHGA, CLDN3, ACPP, ENO2, CEACAM3
16lipid4411.3IBSP, AMACR, IFI27, CHGA, KRT7, ACPP
17matrigel4411.3IBSP, CSTA, FOLH1, CHGA, KRT7
18estracyt4411.2KLK3, CHGA, ACPP, ENO2
19mucicarmine4411.2KLK3, KRT7, KRT20, CEACAM3
20flutamide44 59 1113.2ENO2, ACPP, CHGA, KLK3
21b 7234411.2CHGA, KRT7, KRT20, CEACAM3
22doxorubicin44 49 1113.2CEACAM3, KRT20, FOLH1, IFI27, KLK3
23sialic acid4411.2IBSP, KRT7, ENO2, CEACAM3
24estramustine phosphate4411.1KLK3, CHGA, ACPP
25guanine44 11 2413.1KLK3, AMACR, IFI27
26estramustine44 1112.1ACPP, CHGA, KLK3
275-hydroxyindoleacetic acid44 2412.1CHGA, ENO2, CEACAM3
28dtpa4411.1KLK3, ACPP, CEACAM3
29acth4411.1CHGA, ACPP, ENO2, CEACAM3
30creatinine4411.1IBSP, CHGA, ACPP, ENO2, CEACAM3
31estrogen4411.1ACPP, KLK3
32bicalutamide44 59 1113.1KLK3, CHGA, ACPP
33methotrexate44 49 1113.1FOLH1, KRT7, ENO2, CEACAM3
34diethylstilbestrol44 28 1113.0KLK3, ACPP, ENO2
35prostascint4411.0FOLH1, KLK3
36yttrium4411.0CEACAM3, FOLH1
37deoxyribonucleic acid4411.0ACPP, AMACR, KLK3
38provenge4411.0ACPP, KLK3
39cysteine4411.0MSMB, CHGA, FOLH1, CSTA, AMACR, IBSP
40indium4411.0CEACAM3, FOLH1
41ribonucleic acid4410.9FOLH1, CHGA, KRT20, ENO2
42chlormadinone acetate4410.9ACPP, KLK3
43smcc4410.9ENO2, CHGA
44hydroxyapatite4410.9MSMB, BMP3, IBSP
45metanephrine44 2411.9ENO2, CHGA
46carboplatin44 49 1112.8ENO2, CHGA, KLK3
47s 1004410.8ENO2, CHGA
48silver4410.7IBSP, CHGA, ENO2
49methionine4410.7CHGA, IFI27, AMACR, IBSP
50vanillylmandelic acid44 2411.3CHGA, ENO2

GO Terms for genes affiliated with Prostate Adenocarcinoma

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Products for genes affiliated with Prostate Adenocarcinoma

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Sources for Prostate Adenocarcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet