MCID: PRS039
MIFTS: 48

Prostate Adenocarcinoma malady

Summaries for Prostate Adenocarcinoma

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63Wikipedia, 32MalaCards
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Wikipedia:63 Prostate cancer is a form of cancer that develops in the prostate, a gland in the male reproductive... more...

MalaCards: Prostate Adenocarcinoma, also known as adenocarcinoma of prostate, is related to adenocarcinoma and prostatitis. An important gene associated with Prostate Adenocarcinoma is CTNND2 (catenin (cadherin-associated protein), delta 2). The compounds tyrosine and paraffin have been mentioned in the context of this disorder. Affiliated tissues include prostate, bone and lymph node.

Aliases & Classifications for Prostate Adenocarcinoma

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8Disease Ontology, 46OMIM, 60UMLS, 39NCIt, 56SNOMED-CT
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Aliases & Descriptions:

prostate adenocarcinoma 8 46
adenocarcinoma of prostate 8 60


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Disease Ontology8 DOID:2526
SNOMED-CT56 399490008
NCIt39 C2919

Related Diseases for Prostate Adenocarcinoma

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17GeneCards, 18GeneDecks
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Diseases related to Prostate Adenocarcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 151)
idRelated DiseaseScoreTop Affiliating Genes
1adenocarcinoma32.1KLK3, IBSP, AMACR, IFI27, ALOX15B, CEACAM3
2prostatitis32.1ACPP, KLK3
3prostate cancer30.8ACPP, KLK3
4prostate disease30.6ACPP, FOLH1, AMACR, KLK3
5bladder adenocarcinoma30.6KLK3, KRT7, KRT20
6adenoma30.5AMACR, IFI27, CHGA, CLDN3, KRT7, KRT20
7lung adenocarcinoma30.5AMACR, KRT7, KRT20, CEACAM3
8bladder carcinoma30.5KRT20
9prostatic adenoma30.5ACPP, KLK3
10nephrogenic adenoma30.5KRT7, AMACR
11transitional cell carcinoma30.3KLK3, IFI27, FOLH1, KRT7, KRT20, ENO2
12squamous cell carcinoma30.2CHGA, CSTA, IFI27, AMACR, IBSP, CLDN3
13lung small cell carcinoma30.2KLK3, AMACR, CHGA, KRT7, KRT20, ACPP
14gastric adenocarcinoma30.2CHGA, CLDN3, KRT7, KRT20
15cervical adenocarcinoma30.2KRT20, KRT7, IFI27
16papilloma30.2IFI27, KRT20
17signet ring cell adenocarcinoma30.0CHGA, KRT7, KRT20
18lung cancer29.9IBSP, AMACR, IFI27, CSTA, CHGA, MSMB
19tubular adenocarcinoma29.9CHGA, KRT7, KRT20, ENO2
20neuroendocrine carcinoma29.9CHGA, KRT7, KRT20, ENO2
21non-small cell lung carcinoma29.9IBSP, IFI27, CSTA, CHGA, ENO2
22cystadenoma29.9CEACAM3, KRT7
23melanoma29.9IBSP, AMACR, IFI27, FOLH1, ENO2, CEACAM3
24colon adenocarcinoma29.9KRT20
25sertoli cell tumor29.9ENO2
26bladder transitional cell carcinoma29.9KRT20, IFI27
27adenocarcinoma in situ10.3
28breast adenocarcinoma10.3
29papillary adenocarcinoma10.3
30seminal vesicle adenocarcinoma10.3
31prostate small cell carcinoma10.3
32lymphoepithelioma-like acinar prostate adenocarcinoma10.3
33small cell carcinoma10.3
34choroiditis10.2
35prostate transitional cell carcinoma10.2
36myeloma10.2
37retinoblastoma10.2
38urethra adenocarcinoma10.2
39cushing's syndrome10.1
40priapism10.1
41nephrogenic adenoma of the urethra10.1
42prostate squamous cell carcinoma10.1
43prostatic acinar adenocarcinoma10.1
44cervicitis10.1
45herpes simplex10.1
46liposarcoma10.1
47lung squamous cell carcinoma10.1
48meningioma10.1
49multiple myeloma10.1
50rectum adenocarcinoma10.1

Graphical network of the top 20 diseases related to Prostate Adenocarcinoma:



Diseases related to prostate adenocarcinoma

Clinical Features for Prostate Adenocarcinoma

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Drugs & Therapeutics for Prostate Adenocarcinoma

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Prostate Adenocarcinoma

Drug clinical trials:

Search ClinicalTrials for Prostate Adenocarcinoma

Search NIH Clinical Center for Prostate Adenocarcinoma

Search CenterWatch for Prostate Adenocarcinoma

Genetic Tests for Prostate Adenocarcinoma

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Anatomical Context for Prostate Adenocarcinoma

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32MalaCards
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MalaCards organs/tissues related to Prostate Adenocarcinoma:

32
Prostate, Bone, Lymph node, Lung, Breast, Endothelial, Skin, Spinal cord, Colon, Bone marrow, Pituitary, Liver, Brain, T cells, Monocytes, B cells, Myeloid, Cervix, Testes, Testis, Kidney, Thyroid

Animal Models for Prostate Adenocarcinoma or affiliated genes

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Publications for Prostate Adenocarcinoma

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50PubMed
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Articles related to Prostate Adenocarcinoma:

(show top 50)    (show all 917)
idTitleAuthorsYear
1
ERG expression and prostatic adenocarcinoma. (23703293)
2013
2
Small cell carcinoma of the prostate after high-dose-rate brachytherapy for low-risk prostatic adenocarcinoma. (23255893)
2013
3
Architectural heterogeneity and cribriform pattern predict adverse clinical outcome for Gleason grade 4 prostatic adenocarcinoma. (24145642)
2013
4
Passive bioelectrical properties for assessing high- and low-grade prostate adenocarcinoma. (21520155)
2011
5
Increased gene copy number of ERG on chromosome 21 but not TMPRSS2-ERG fusion predicts outcome in prostatic adenocarcinomas. (21743434)
2011
6
Quantified gene expression levels for phase I/II metabolizing enzyme and estrogen receptor levels in benign prostate from cohorts designated as high-risk (UK) versus low-risk (India) for adenocarcinoma at this organ site: a preliminary study. (19935673)
2010
7
Lymphatic vessel densities of lymph node-negative prostate adenocarcinoma in Korea. (19058917)
2009
8
Brain metastases from prostate adenocarcinoma. (19155207)
2009
9
Prognostic significance of cell proliferation, microvascular density and androgen receptor level in prostatic adenocarcinoma]. (20210018)
2009
10
S-100A1 is a reliable marker in distinguishing nephrogenic adenoma from prostatic adenocarcinoma. (19384190)
2009
11
Histopathological changes induced by therapies in the benign prostate and prostate adenocarcinoma. (17128417)
2007
12
Alpha-methylacyl-CoA racemase (P504S)/34betaE12/p63 triple cocktail stain in prostatic adenocarcinoma after hormonal therapy. (17134736)
2007
13
Neuroendocrine-like prostate cancer cells: neuroendocrine transdifferentiation of prostate adenocarcinoma cells. (17914087)
2007
14
Inducible FGFR-1 activation leads to irreversible prostate adenocarcinoma and an epithelial-to-mesenchymal transition. (18068632)
2007
15
Nephrogenic adenoma: immunohistochemical evaluation for its etiology and differentiation from prostatic adenocarcinoma. (16740031)
2006
16
Dose escalation of oral vinorelbine in combination with estramustine in hormone-refractory adenocarcinoma of the prostate. (16691618)
2006
17
Androgen suppression plus radiation versus radiation alone for patients with stage D1/pathologic node-positive adenocarcinoma of the prostate: updated results based on national prospective randomized trial Radiation Therapy Oncology Group 85-31. (15681524)
2005
18
Clear cell adenocarcinoma of the prostatic utricle in an adolescent. (15944958)
2005
19
Effect of GnRH analogs on the expression of TrkA and p75 neurotrophin receptors in primary cell cultures from human prostate adenocarcinoma. (15948150)
2005
20
Intestinal-type mucinous adenocarcinoma arising from the prostatic duct. (15948756)
2005
21
Benign fibrous histiocytoma: a rare finding on bone scan staging for prostate adenocarcinoma. (12684127)
2003
22
Cholestatic jaundice as a paraneoplastic manifestation of prostate adenocarcinoma. (15017648)
2003
23
Expression pattern of mouse homolog of prostate-specific membrane antigen (FOLH1) in the transgenic adenocarcinoma of the mouse prostate model. (12712410)
2003
24
Expression of group IIA secretory phospholipase A2 is elevated in prostatic intraepithelial neoplasia and adenocarcinoma. (11839587)
2002
25
Skin lesions in malignancy. Case 2. Skin metastases from prostate adenocarcinoma. (11283145)
2001
26
Peroxisome proliferator-activated receptor alpha is an androgen-responsive gene in human prostate and is highly expressed in prostatic adenocarcinoma. (10955810)
2000
27
Androgenic regulation of growth factor and growth factor receptor expression in the CWR22 model of prostatic adenocarcinoma. (10399960)
1999
28
Hevin, an antiadhesive extracellular matrix protein, is down-regulated in metastatic prostate adenocarcinoma. (9443398)
1998
29
Prostatic adenocarcinoma with atrophic features: a study of 202 consecutive completely embedded radical prostatectomy specimens. (9620026)
1998
30
Isolation and characterization of propagable cell lines (HUNC) from the androgen-sensitive Dunning R3327H rat prostatic adenocarcinoma. (9600341)
1998
31
Quantitative immunohistochemical analysis of insulin-like growth factor binding protein-3 in human prostatic adenocarcinoma: a prognostic study. (9598573)
1998
32
Chromosomal anomalies in stage D1 prostate adenocarcinoma primary tumors and lymph node metastases detected by fluorescence in situ hybridization. (8976257)
1997
33
High incidence and histogenesis of seminal vesicle adenocarcinoma and lower incidence of prostate carcinomas in the Lobund-Wistar prostate cancer rat model using N-nitrosomethylurea and testosterone. (8885183)
1996
34
Cytology of metastatic adenocarcinoma of the prostate in pleural effusions. (8872430)
1996
35
DNA ploidy, serum prostate specific antigen, histological grade and immunohistochemistry as predictive parameters of lymph node metastases in T1-T3/M0 prostatic adenocarcinoma. (7531589)
1995
36
Characterization of human relaxin gene regulation in the relaxin-expressing human prostate adenocarcinoma cell line LNCaP.FGC. (8800640)
1995
37
Differentiation-stage specific expression of oncoprotein 18 in human and rat prostatic adenocarcinoma. (7638082)
1995
38
Proliferating cell nuclear antigen and p53 expression as prognostic factors in T1-2M0 prostatic adenocarcinoma. (7913085)
1994
39
Prognostic value of c-erbB-2 and epidermal growth factor receptor in stage A1 (T1a) prostatic adenocarcinoma. (7921940)
1994
40
Immunohistochemistry analysis of platelet-derived growth factor A and B chains and platelet-derived growth factor alpha and beta receptor expression in benign prostatic hyperplasias and Gleason-graded human prostate adenocarcinomas. (7524068)
1994
41
Comparison of fluorescence in situ hybridization with flow cytometry and static image analysis in ploidy analysis of paraffin-embedded prostate adenocarcinoma. (8026827)
1994
42
Proliferating cell nuclear antigen (PCNA) in prostatic invasive adenocarcinoma. Is the proliferation state in the marginal zone of the tumour higher than in the central part? (8097389)
1993
43
IGF-I and IGF-binding proteins: stimulatory and inhibitory factors secreted by human prostatic adenocarcinoma cells. (1722685)
1991
44
Nuclear deoxyribonucleic acid ploidy and serum prostate specific antigen in operable prostatic adenocarcinoma. (1695690)
1990
45
Evaluation of tumor progression by repeated fine needle biopsies in prostate adenocarcinoma: modal deoxyribonucleic acid value and cytological differentiation. (2231936)
1990
46
Mucinous adenocarcinoma of the prostate presenting as a retrovesical cyst. Case report. (2847308)
1988
47
Adriamycin-vitamin E combination therapy for treatment of prostate adenocarcinoma in the Nb rat model. (3411971)
1988
48
Prostatic adenocarcinoma with concurrent Sertoli cell tumor in a dog. (7340923)
1981
49
Evaluation of nonhormonal cytotoxic chemotherapy in the Nb rat prostate adenocarcinoma: autonomous tumor (18-Pr and 13-Pr). (7388771)
1980
50
Papillomatosis and papillary adenocarcinoma of prostatic ducts: a case report. (5532917)
1970

Genetic Variations for Prostate Adenocarcinoma

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Expression for genes affiliated with Prostate Adenocarcinoma

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Prostate Adenocarcinoma

Search GEO for disease gene expression data for Prostate Adenocarcinoma.

Pathways for genes affiliated with Prostate Adenocarcinoma

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Compounds for genes affiliated with Prostate Adenocarcinoma

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Sources:
44Novoseek, 49PharmGKB, 11DrugBank, 24HMDB, 59Tocris Bioscience, 28IUPHAR
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Compounds related to Prostate Adenocarcinoma according to GeneCards/GeneDecks:

(show top 50)    (show all 58)
idCompoundScoreTop Affiliating Genes
1tyrosine4411.9CTNND2, CEACAM3, IBSP, AMACR, ENO2, MSMB
2paraffin4411.8IFI27, KRT7, ENO2, KLK3, AMACR, ALOX15B
3vegf4411.8ENO2, ACPP, KRT20, KRT7, CLDN3, CHGA
4calcium44 49 11 2414.8BMP3, CLDN3, MSMB, ENO2, CHGA, AMACR
5testosterone44 59 11 2414.7AMACR, KLK3, IFI27, CHGA, KRT7, ENO2
6hematoxylin4411.6KRT20, KRT7, CHGA, AMACR, IBSP, ACPP
7steroid4411.6IBSP, CHGA, IFI27, CEACAM3, KLK3, MSMB
8progesterone44 59 28 11 2415.5ACPP, ENO2, CEACAM3, KRT20, KRT7, CHGA
9vitamin d4411.4ACPP, IFI27, IBSP, KLK3, CHGA, AMACR
10dexamethasone44 49 28 1114.4KLK3, IBSP, AMACR, BMP3, IFI27, ENO2
11lactate4411.4KLK3, IFI27, CHGA, ACPP, ENO2, CEACAM3
12thymidine44 2412.3CEACAM3, ENO2, IFI27, IBSP, ACPP, FOLH1
13streptavidin4411.3CEACAM3, FOLH1, AMACR, KRT20, KRT7
14formaldehyde44 2412.3KRT20, CHGA, KLK3, ENO2, KRT7
15cholesterol44 28 11 2414.3ENO2, CLDN3, CHGA, CEACAM3, AMACR, ACPP
16lipid4411.3ENO2, IFI27, AMACR, IBSP, KRT7, ACPP
17matrigel4411.3KRT7, FOLH1, IBSP, CHGA, CSTA
18estracyt4411.2KLK3, ACPP, CHGA, ENO2
19mucicarmine4411.2CEACAM3, KRT20, KRT7, KLK3
20flutamide44 59 1113.2ACPP, ENO2, CHGA, KLK3
21b 7234411.2CHGA, KRT20, CEACAM3, KRT7
22doxorubicin44 49 1113.2KLK3, FOLH1, CEACAM3, KRT20, IFI27
23sialic acid4411.2KRT7, CEACAM3, IBSP, ENO2
24estramustine phosphate4411.1ACPP, CHGA, KLK3
25guanine44 11 2413.1IFI27, KLK3, AMACR
26estramustine44 1112.1CHGA, KLK3, ACPP
275-hydroxyindoleacetic acid44 2412.1CEACAM3, ENO2, CHGA
28dtpa4411.1CEACAM3, KLK3, ACPP
29acth4411.1CHGA, ACPP, CEACAM3, ENO2
30creatinine4411.1ACPP, CEACAM3, IBSP, CHGA, ENO2
31estrogen4411.1ACPP, KLK3
32bicalutamide44 59 1113.1CHGA, KLK3, ACPP
33methotrexate44 49 1113.1KRT7, ENO2, FOLH1, CEACAM3
34diethylstilbestrol44 28 1113.0ENO2, ACPP, KLK3
35prostascint4411.0KLK3, FOLH1
36yttrium4411.0FOLH1, CEACAM3
37deoxyribonucleic acid4411.0AMACR, ACPP, KLK3
38provenge4411.0ACPP, KLK3
39cysteine4411.0FOLH1, IBSP, AMACR, MSMB, CSTA, CHGA
40indium4411.0CEACAM3, FOLH1
41ribonucleic acid4410.9KRT20, ENO2, FOLH1, CHGA
42chlormadinone acetate4410.9ACPP, KLK3
43smcc4410.9CHGA, ENO2
44hydroxyapatite4410.9MSMB, IBSP, BMP3
45metanephrine44 2411.9ENO2, CHGA
46carboplatin44 49 1112.8ENO2, CHGA, KLK3
47s 1004410.8ENO2, CHGA
48silver4410.7ENO2, IBSP, CHGA
49methionine4410.7IBSP, AMACR, IFI27, CHGA
50vanillylmandelic acid44 2411.3ENO2, CHGA

GO Terms for genes affiliated with Prostate Adenocarcinoma

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Products for genes affiliated with Prostate Adenocarcinoma

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Sources for Prostate Adenocarcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet