MCID: PRS039
MIFTS: 41

Prostate Adenocarcinoma malady

Summaries for Prostate Adenocarcinoma

Sources:
64Wikipedia, 33MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:64 Prostate cancer is a form of cancer that develops in the prostate, a gland in the male reproductive... more...

MalaCards: Prostate Adenocarcinoma, also known as adenocarcinoma of prostate, is related to adenocarcinoma and adenoma. An important gene associated with Prostate Adenocarcinoma is CTNND2 (catenin (cadherin-associated protein), delta 2). The compounds tyrosine and paraffin have been mentioned in the context of this disorder.

Aliases & Classifications for Prostate Adenocarcinoma

Sources:
8Disease Ontology, 47OMIM, 61UMLS, 40NCIt, 57SNOMED-CT
See all sources

Aliases & Descriptions:

prostate adenocarcinoma 8 47
adenocarcinoma of prostate 8 61


External Ids:

Disease Ontology8 DOID:2526
SNOMED-CT57 399490008
NCIt40 C2919

Related Diseases for Prostate Adenocarcinoma

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Prostate Adenocarcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 138)
idRelated DiseaseScoreTop Affiliating Genes
1adenocarcinoma32.1KLK3, IBSP, AMACR, IFI27, ALOX15B, CEACAM3
2adenoma30.6AMACR, IFI27, CHGA, CLDN3, KRT7, KRT20
3bladder adenocarcinoma30.6KLK3, KRT7, KRT20
4bladder carcinoma30.6KRT20
5prostatic adenoma30.6ACPP, KLK3
6nephrogenic adenoma30.5KRT7, AMACR
7transitional cell carcinoma30.3KLK3, IFI27, FOLH1, KRT7, KRT20, ENO2
8squamous cell carcinoma30.2CHGA, CSTA, IFI27, AMACR, IBSP, CLDN3
9signet ring cell adenocarcinoma30.1CHGA, KRT7, KRT20
10tubular adenocarcinoma30.0CHGA, KRT7, KRT20, ENO2
11neuroendocrine carcinoma30.0CHGA, KRT7, KRT20, ENO2
12cystadenoma30.0CEACAM3, KRT7
13sertoli cell tumor30.0ENO2
14bladder transitional cell carcinoma30.0KRT20, IFI27
15breast adenocarcinoma10.3
16seminal vesicle adenocarcinoma10.3
17lymphoepithelioma-like acinar prostate adenocarcinoma10.3
18small cell carcinoma10.3
19prostate small cell carcinoma10.2
20prostatic cyst10.2
21n syndrome10.2
22urethra adenocarcinoma10.2
23cushing's syndrome10.2
24priapism10.2
25prostate transitional cell carcinoma10.2
26prostate squamous cell carcinoma10.2
27adenocarcinoma in situ10.2
28prostatic acinar adenocarcinoma10.2
29cerebellar degeneration10.2
30chylous ascites10.2
31malakoplakia10.2
32paraneoplastic cerebellar degeneration10.2
33somatostatin analog10.2
34nodular prostate10.0
35bullous pemphigoid10.0
36lung occult adenocarcinoma10.0
37neuromyelitis optica10.0
38osteonecrosis10.0
39fibrous histiocytoma10.0
40prostate signet ring cell adenocarcinoma10.0
41pleomorphic liposarcoma10.0
42pituitary apoplexy10.0
43diabetes insipidus10.0
44gastrointestinal stromal tumor10.0
45inflammatory breast carcinoma10.0
46anal canal carcinoma10.0
47adenomatoid tumor10.0
48prostate leiomyosarcoma10.0
49prostate lymphoma10.0
50mucinous adenocarcinoma10.0

Graphical network of the top 20 diseases related to Prostate Adenocarcinoma:



Diseases related to prostate adenocarcinoma

Clinical Features for Prostate Adenocarcinoma

Drugs & Therapeutics for Prostate Adenocarcinoma

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Prostate Adenocarcinoma

Drug clinical trials:

Search ClinicalTrials for Prostate Adenocarcinoma

Search NIH Clinical Center for Prostate Adenocarcinoma

Search CenterWatch for Prostate Adenocarcinoma

Genetic Tests for Prostate Adenocarcinoma

Anatomical Context for Prostate Adenocarcinoma

Animal Models for Prostate Adenocarcinoma or affiliated genes

Sources:
28inGenious Targeting Laboratory
See all sources

Publications for Prostate Adenocarcinoma

Sources:
51PubMed
See all sources

Articles related to Prostate Adenocarcinoma:

(show top 50)    (show all 710)
idTitleAuthorsYear
1
Mandibular metastasis of adenocarcinoma from prostate cancer: case report according to epidemiology and current therapeutical trends of the advanced prostate cancer. (24212997)
2013
2
Characteristics of modern Gleason 9/10 prostate adenocarcinoma: a single tertiary centre experience within the Republic of Ireland. (24129893)
2013
3
Transmembrane prostatic acid phosphatase (TMPAP) interacts with snapin and deficient mice develop prostate adenocarcinoma. (24039861)
2013
4
Prostate cancer originating in basal cells progresses to adenocarcinoma propagated by luminal-like cells. (24282295)
2013
5
Metastatic prostate adenocarcinoma presenting central diabetes insipidus. (22474455)
2012
6
Inter/intra-observer reproducibility of Gleason scoring in prostate adenocarcinoma in Iranian pathologists. (22641492)
2012
7
Toxicity report of once weekly radiation therapy for low-risk prostate adenocarcinoma: preliminary results of a phase I/II trial. (21906281)
2011
8
An 82-year-old Caucasian man with a ductal prostate adenocarcinoma with unusual cystoscopic appearance: a case report. (21223563)
2011
9
Significance of prostate adenocarcinoma perineural invasion on biopsy in patients who are otherwise candidates for active surveillance. (21679997)
2011
10
Can telomere alterations predict biochemical recurrence in prostate adenocarcinoma? A preliminary study. (20674190)
2010
11
Retinoid metabolism and ALDH1A2 (RALDH2) expression are altered in the transgenic adenocarcinoma mouse prostate model. (19549509)
2009
12
Three simultaneous paraneoplastic manifestations (ichthyosis acquisita, Bazex syndrome, and Leser-TrAclat sign) with prostate adenocarcinoma. (19700026)
2009
13
Evaluation of silibinin on the viability, migration and adhesion of the human prostate adenocarcinoma (PC-3) cell line. (18538589)
2008
14
Ductal adenocarcinoma of the prostate: current opinion and controversies. (18773743)
2008
15
Aberrant diffuse expression of p63 in adenocarcinoma of the prostate on needle biopsy and radical prostatectomy: report of 21 cases. (18300803)
2008
16
Phase II evaluation of oral estramustine, oral etoposide, and intravenous paclitaxel in patients with hormone-sensitive prostate adenocarcinoma. (17645828)
2007
17
Mouse models of prostate adenocarcinoma with the capacity to monitor spontaneous carcinogenesis by bioluminescence or fluorescence. (17671224)
2007
18
Diagnostic utility of p501s (prostein) in comparison to prostate specific antigen (PSA) for the detection of metastatic prostatic adenocarcinoma. (17963516)
2007
19
Increased expression of cyclooxygenase-2 correlates with resistance to radiation in human prostate adenocarcinoma cells. (17437847)
2007
20
Serum testosterone, dihydrotestosterone, luteinizing hormone and follicle-stimulating hormone versus prostate specific antigen in patients with localized prostate adenocarcinoma who underwent radical prostatectomy. Radioimmunoassays measurements]. (17450256)
2007
21
Prostate-specific membrane antigen (PSMA) protein expression in normal and neoplastic tissues and its sensitivity and specificity in prostate adenocarcinoma: an immunohistochemical study using mutiple tumour tissue microarray technique. (17448023)
2007
22
hZip2 and hZip3 zinc transporters are down regulated in human prostate adenocarcinomatous glands. (17550612)
2007
23
Characterization of circulating blood dendritic cell subsets DC123+ (lymphoid) and DC11C+ (myeloid) in prostate adenocarcinoma patients. (17075798)
2007
24
Comparative in vitro and in vivo evaluation of two 64Cu-labeled bombesin analogs in a mouse model of human prostate adenocarcinoma. (16631086)
2006
25
Differential expression of human leukocyte antigen-G (HLA-G) messenger RNAs and proteins in normal human prostate and prostatic adenocarcinoma. (16616377)
2006
26
Myofibroblastic stromal reaction and expression of tenascin-C and laminin in prostate adenocarcinoma. (16652121)
2006
27
Dose escalation of oral vinorelbine in combination with estramustine in hormone-refractory adenocarcinoma of the prostate. (16691618)
2006
28
Prostate adenocarcinoma manifesting as generalized lymphadenopathy. (16678051)
2006
29
A decrease in 1H nuclear magnetic resonance spectroscopically determined citrate in human seminal fluid accompanies the development of prostate adenocarcinoma. (15643195)
2005
30
Recurrent pulmonary embolism in an elderly patient with Cushing's syndrome, adrenocortical adenoma, pheochromocytoma and prostate adenocarcinoma. (15510934)
2004
31
Activation of signal transducer and activator of transcription 5 is required for progression of autochthonous prostate cancer: evidence from the transgenic adenocarcinoma of the mouse prostate system. (14695191)
2003
32
Real-time RT-PCR for the measurement of prostate-specific antigen mRNA expression in benign hyperplasia and adenocarcinoma of prostate. (12705330)
2003
33
Clear cell adenocarcinoma of the female urethra showing strong immunostaining for prostate-specific antigen. (11251541)
2001
34
A retrospective analysis of the results of p(65) + Be neutrontherapy for the treatment of prostate adenocarcinoma at the cyclotron of Louvain-la-Neuve. Part I: Survival and progression-free survival. (11446080)
2001
35
Secretion of a soluble T cell promoting factor by the human prostate adenocarcinoma cell line DU-145. (11396169)
2001
36
On the use of cytokeratins 7 and 20 in the differentiation between transitional cell carcinoma and prostate adenocarcinoma. (11190802)
2001
37
Karyotypic similarity identified by multiplex-FISH relates four prostate adenocarcinoma cell lines: PC-3, PPC-1, ALVA-31, and ALVA-41. (11433521)
2001
38
Diagnosis of prostate adenocarcinoma using transurethral resection of the prostate after multiple negative transrectal biopsies and persistently elevated prostate-specific antigen level. (11113765)
2000
39
Pitfalls in the diagnosis of prostate adenocarcinoma from holmium resection of the prostate. (10963483)
2000
40
Bone metastases from poorly differentiated adenocarcinoma of the prostate diagnosed by In-111 ProstaScint (Capromab Pendetide) images with negative results of Tc-99m MDP bone scan and without significant elevation of prostate-specific antigen. (10551485)
1999
41
The role of the detection of hematogenous micrometastasis in prostate adenocarcinoma and malignant melanoma by RT-PCR. (10085416)
1999
42
Prostate-specific antigen expression and lipochrome pigment granules in the differential diagnosis of prostatic adenocarcinoma versus seminal vesicle-ejaculatory duct epithelium. (10539914)
1999
43
Prostate-specific membrane antigen expression is greatest in prostate adenocarcinoma and lymph node metastases. (9763084)
1998
44
Rearrangement of the long arm of chromosome 10 in the prostate adenocarcinoma cell line LNCaP. (9530332)
1998
45
Chromosome 10 alterations in prostate adenocarcinoma (review). (9769364)
1998
46
Extramammary Paget's disease associated with prostate adenocarcinoma. (7516910)
1994
47
Tumor-promoting phorbol ester-induced cell death and gene expression in a human prostate adenocarcinoma cell line. (7841543)
1994
48
Two cases of mucinous adenocarcinoma of the prostate]. (1326881)
1992
49
Mucinous adenocarcinoma of prostate: a case report and review of the literature. (3007780)
1986
50
Unusual metastatic patterns of prostate adenocarcinoma. (6195357)
1983

Genetic Variations for Prostate Adenocarcinoma

Expression for genes affiliated with Prostate Adenocarcinoma

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Prostate Adenocarcinoma

Search GEO for disease gene expression data for Prostate Adenocarcinoma.

Pathways for genes affiliated with Prostate Adenocarcinoma

Compounds for genes affiliated with Prostate Adenocarcinoma

Sources:
45Novoseek, 50PharmGKB, 11DrugBank, 24HMDB, 60Tocris Bioscience, 29IUPHAR
See all sources

Compounds related to Prostate Adenocarcinoma according to GeneCards/GeneDecks:

(show top 50)    (show all 58)
idCompoundScoreTop Affiliating Genes
1tyrosine4511.9IBSP, AMACR, IFI27, CSTA, CTNND2, CHGA
2paraffin4511.8ALOX15B, KLK3, IBSP, CEACAM3, ENO2, ACPP
3vegf4511.8KLK3, IBSP, IFI27, FOLH1, CHGA, CLDN3
4calcium45 50 11 2414.8RLN1, IBSP, AMACR, IFI27, BMP3, CHGA
5testosterone45 60 11 2414.7FOLH1, IFI27, AMACR, KLK3, CHGA, KRT7
6hematoxylin4511.6CEACAM3, ENO2, ACPP, KRT20, KRT7, CHGA
7steroid4511.6KLK3, IBSP, IFI27, CHGA, ACPP, MSMB
8progesterone45 60 29 11 2415.5AMACR, IFI27, CHGA, KRT7, KRT20, ACPP
9vitamin d4511.4ACPP, CHGA, IFI27, AMACR, IBSP, KLK3
10dexamethasone45 50 29 1114.4KLK3, IBSP, AMACR, IFI27, BMP3, ENO2
11lactate4511.4KLK3, IFI27, CHGA, ACPP, ENO2, CEACAM3
12thymidine45 2412.3IBSP, IFI27, FOLH1, ACPP, ENO2, CEACAM3
13streptavidin4511.3AMACR, FOLH1, KRT7, KRT20, CEACAM3
14formaldehyde45 2412.3KLK3, CHGA, KRT7, KRT20, ENO2
15cholesterol45 29 11 2414.3AMACR, CHGA, CLDN3, ACPP, ENO2, CEACAM3
16lipid4511.3IBSP, AMACR, IFI27, CHGA, KRT7, ACPP
17matrigel4511.3IBSP, CSTA, FOLH1, CHGA, KRT7
18estracyt4511.2KLK3, CHGA, ACPP, ENO2
19mucicarmine4511.2KLK3, KRT7, KRT20, CEACAM3
20flutamide45 60 1113.2ENO2, ACPP, CHGA, KLK3
21b 7234511.2CHGA, KRT7, KRT20, CEACAM3
22doxorubicin45 50 1113.2CEACAM3, KRT20, FOLH1, IFI27, KLK3
23sialic acid4511.2IBSP, KRT7, ENO2, CEACAM3
24estramustine phosphate4511.1KLK3, CHGA, ACPP
25guanine45 11 2413.1KLK3, AMACR, IFI27
26estramustine45 1112.1ACPP, CHGA, KLK3
275-hydroxyindoleacetic acid45 2412.1CHGA, ENO2, CEACAM3
28dtpa4511.1KLK3, ACPP, CEACAM3
29acth4511.1CHGA, ACPP, ENO2, CEACAM3
30creatinine4511.1IBSP, CHGA, ACPP, ENO2, CEACAM3
31estrogen4511.1ACPP, KLK3
32bicalutamide45 60 1113.1KLK3, CHGA, ACPP
33methotrexate45 50 1113.1FOLH1, KRT7, ENO2, CEACAM3
34diethylstilbestrol45 29 1113.0KLK3, ACPP, ENO2
35prostascint4511.0FOLH1, KLK3
36yttrium4511.0CEACAM3, FOLH1
37deoxyribonucleic acid4511.0ACPP, AMACR, KLK3
38provenge4511.0ACPP, KLK3
39cysteine4511.0MSMB, CHGA, FOLH1, CSTA, AMACR, IBSP
40indium4511.0CEACAM3, FOLH1
41ribonucleic acid4510.9FOLH1, CHGA, KRT20, ENO2
42chlormadinone acetate4510.9ACPP, KLK3
43smcc4510.9ENO2, CHGA
44hydroxyapatite4510.9MSMB, BMP3, IBSP
45metanephrine45 2411.9ENO2, CHGA
46carboplatin45 50 1112.8ENO2, CHGA, KLK3
47s 1004510.8ENO2, CHGA
48silver4510.7IBSP, CHGA, ENO2
49methionine4510.7CHGA, IFI27, AMACR, IBSP
50vanillylmandelic acid45 2411.3CHGA, ENO2

GO Terms for genes affiliated with Prostate Adenocarcinoma

Products for genes affiliated with Prostate Adenocarcinoma

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Prostate Adenocarcinoma

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet