MCID: PRS007
MIFTS: 22

Prostate Calculus

Categories: Reproductive diseases

Aliases & Classifications for Prostate Calculus

MalaCards integrated aliases for Prostate Calculus:

Name: Prostate Calculus 12 14
Calculus of Prostate 12 69
Prostatic Lithiasis 12
Stone of Prostate 12
Prostatic Stone 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13689
ICD10 32 N42.0
ICD9CM 34 602.0
NCIt 46 C26936
UMLS 69 C0149525

Summaries for Prostate Calculus

MalaCards based summary : Prostate Calculus, also known as calculus of prostate, is related to alkaptonuria and ochronosis. An important gene associated with Prostate Calculus is HPD (4-Hydroxyphenylpyruvate Dioxygenase), and among its related pathways/superpathways are Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways and Integrated Breast Cancer Pathway. Affiliated tissues include prostate, and related phenotypes are Decreased caspase 3/7 activity and renal/urinary system

Related Diseases for Prostate Calculus

Diseases related to Prostate Calculus via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 alkaptonuria 32.1 HGD HPD
2 ochronosis 9.9 HGD HPD
3 bladder disease 9.8
4 neurogenic bladder 9.8
5 prostatitis 9.8
6 male reproductive organ cancer 9.5 AR CASP3
7 reproductive organ cancer 9.4 AR CASP3
8 wilms tumor 1 9.3 AR CASP3
9 lower urinary tract calculus 9.1 AR C1orf210 HGD HPD

Comorbidity relations with Prostate Calculus via Phenotypic Disease Network (PDN):


Bladder Neck Obstruction Prostate Cancer
Prostatic Hypertrophy Prostatitis
Urethral Stricture Urinary Tract Obstruction

Graphical network of the top 20 diseases related to Prostate Calculus:



Diseases related to Prostate Calculus

Symptoms & Phenotypes for Prostate Calculus

GenomeRNAi Phenotypes related to Prostate Calculus according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased caspase 3/7 activity GR00318-A 8.8 AR CASP3 HGD

MGI Mouse Phenotypes related to Prostate Calculus:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 renal/urinary system MP:0005367 8.92 AR CASP3 HGD HPD

Drugs & Therapeutics for Prostate Calculus

Search Clinical Trials , NIH Clinical Center for Prostate Calculus

Genetic Tests for Prostate Calculus

Anatomical Context for Prostate Calculus

MalaCards organs/tissues related to Prostate Calculus:

38
Prostate

Publications for Prostate Calculus

Articles related to Prostate Calculus:

# Title Authors Year
1
Giant vesico-prostatic calculus in a patient with neurogenic bladder disease. A case report. ( 4428188 )
1974

Variations for Prostate Calculus

Expression for Prostate Calculus

Search GEO for disease gene expression data for Prostate Calculus.

Pathways for Prostate Calculus

GO Terms for Prostate Calculus

Biological processes related to Prostate Calculus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 L-phenylalanine catabolic process GO:0006559 8.96 HGD HPD
2 tyrosine catabolic process GO:0006572 8.62 HGD HPD

Molecular functions related to Prostate Calculus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 dioxygenase activity GO:0051213 8.62 HGD HPD

Sources for Prostate Calculus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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