MCID: PRS121
MIFTS: 11

Prostate Cancer/brain Cancer Susceptibility, Somatic

Categories: Genetic diseases, Neuronal diseases, Cancer diseases

Aliases & Classifications for Prostate Cancer/brain Cancer Susceptibility, Somatic

MalaCards integrated aliases for Prostate Cancer/brain Cancer Susceptibility, Somatic:

Name: Prostate Cancer/brain Cancer Susceptibility, Somatic 54
Prostate Cancer/brain Cancer Susceptibility 29

Classifications:



External Ids:

OMIM 54 603688
SNOMED-CT via HPO 65 399068003 126951006

Summaries for Prostate Cancer/brain Cancer Susceptibility, Somatic

MalaCards based summary : Prostate Cancer/brain Cancer Susceptibility, Somatic, is also known as prostate cancer/brain cancer susceptibility, and has symptoms including prostate cancer and neoplasm of the central nervous system. An important gene associated with Prostate Cancer/brain Cancer Susceptibility, Somatic is EPHB2 (EPH Receptor B2). Affiliated tissues include prostate and brain.

Description from OMIM: 603688

Related Diseases for Prostate Cancer/brain Cancer Susceptibility, Somatic

Symptoms & Phenotypes for Prostate Cancer/brain Cancer Susceptibility, Somatic

Clinical features from OMIM:

603688

Human phenotypes related to Prostate Cancer/brain Cancer Susceptibility, Somatic:

32
id Description HPO Frequency HPO Source Accession
1 prostate cancer 32 HP:0012125
2 neoplasm of the central nervous system 32 HP:0100006

Drugs & Therapeutics for Prostate Cancer/brain Cancer Susceptibility, Somatic

Search Clinical Trials , NIH Clinical Center for Prostate Cancer/brain Cancer Susceptibility, Somatic

Genetic Tests for Prostate Cancer/brain Cancer Susceptibility, Somatic

Genetic tests related to Prostate Cancer/brain Cancer Susceptibility, Somatic:

id Genetic test Affiliating Genes
1 Prostate Cancer/brain Cancer Susceptibility 29

Anatomical Context for Prostate Cancer/brain Cancer Susceptibility, Somatic

MalaCards organs/tissues related to Prostate Cancer/brain Cancer Susceptibility, Somatic:

39
Prostate, Brain

Publications for Prostate Cancer/brain Cancer Susceptibility, Somatic

Variations for Prostate Cancer/brain Cancer Susceptibility, Somatic

ClinVar genetic disease variations for Prostate Cancer/brain Cancer Susceptibility, Somatic:

6
id Gene Variation Type Significance SNP ID Assembly Location
1 EPHB2 NM_004442.7(EPHB2): c.2167C> T (p.Gln723Ter) single nucleotide variant Pathogenic rs121912582 GRCh37 Chromosome 1, 23234473: 23234473
2 EPHB2 NM_004442.7(EPHB2): c.835G> T (p.Ala279Ser) single nucleotide variant Pathogenic rs35882952 GRCh37 Chromosome 1, 23189553: 23189553
3 EPHB2 NM_004442.7(EPHB2): c.2035G> A (p.Asp679Asn) single nucleotide variant Pathogenic rs28936395 GRCh37 Chromosome 1, 23233346: 23233346
4 EPHB2 NM_001309193.1(EPHB2): c.3055A> T (p.Lys1019Ter) single nucleotide variant risk factor rs76826147 GRCh37 Chromosome 1, 23240250: 23240250

Expression for Prostate Cancer/brain Cancer Susceptibility, Somatic

Search GEO for disease gene expression data for Prostate Cancer/brain Cancer Susceptibility, Somatic.

Pathways for Prostate Cancer/brain Cancer Susceptibility, Somatic

GO Terms for Prostate Cancer/brain Cancer Susceptibility, Somatic

Sources for Prostate Cancer/brain Cancer Susceptibility, Somatic

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....