MCID: PRS085
MIFTS: 21

Prostate Cancer, Progression of malady

Cancer diseases category

Summaries for Prostate Cancer, Progression of

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Sources:
46OMIM, 32MalaCards
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MalaCards: Prostate Cancer, Progression of is related to malignant glioma and prostate cancer. An important gene associated with Prostate Cancer, Progression of is EPHB2 (EPH receptor B2), and among its related pathways are Akt Signaling and Regulation of Microtubule Cytoskeleton. The compounds pd 98,059 and phosphatidylinositol have been mentioned in the context of this disorder. Affiliated tissues include prostate.

Description from OMIM:46 176807

Aliases & Classifications for Prostate Cancer, Progression of

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46OMIM
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

prostate cancer, progression of 46


Related Diseases for Prostate Cancer, Progression of

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Prostate Cancer, Progression of via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1malignant glioma10.0PTEN, EPHB2
2prostate cancer10.0PTEN, EPHB2
3brain cancer10.0PTEN, EPHB2

Clinical Features for Prostate Cancer, Progression of

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Sources:
46OMIM
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Clinical features from OMIM:

176807

Drugs & Therapeutics for Prostate Cancer, Progression of

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Prostate Cancer, Progression of

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Anatomical Context for Prostate Cancer, Progression of

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Sources:
32MalaCards
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MalaCards organs/tissues related to Prostate Cancer, Progression of:

32
Prostate

Animal Models for Prostate Cancer, Progression of or affiliated genes

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Publications for Prostate Cancer, Progression of

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Genetic Variations for Prostate Cancer, Progression of

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Sources:
62UniProtKB/Swiss-Prot
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Genetic disease variations for Prostate Cancer, Progression of:

62 (show all 21)
id Symbol AA change Variation ID SNP ID
1CHEK2p.Arg180CysVAR_019103rs77130927
2CHEK2p.Arg181CysVAR_019104rs137853010
3CHEK2p.Arg181HisVAR_019105rs121908701
4CHEK2p.Glu239LysVAR_019106
5CHEK2p.Glu64LysVAR_019107
6CHEK2p.Arg145ProVAR_019108
7CHEK2p.Gly167ArgVAR_019109
8CHEK2p.Arg180HisVAR_019110rs137853009
9CHEK2p.Ile251PheVAR_019111
10CHEK2p.Arg318HisVAR_019112rs143611747
11CHEK2p.Thr323ProVAR_019113
12CHEK2p.Tyr327CysVAR_019114
13CHEK2p.Thr476LysVAR_019115
14EPHB2p.Arg199HisVAR_032853
15EPHB2p.Ala279SerVAR_032854rs35882952
16EPHB2p.Val650AlaVAR_032855rs142173175
17EPHB2p.His679AsnVAR_032856
18EPHB2p.Met883ValVAR_032857
19EPHB2p.Ile909MetVAR_032858
20MXI1p.Glu152AlaVAR_004499
21PTENp.Met134LeuVAR_007469

Expression for genes affiliated with Prostate Cancer, Progression of

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Prostate Cancer, Progression of

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Pathways for genes affiliated with Prostate Cancer, Progression of

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Sources:
51QIAGEN, 37NCBI BioSystems Database
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Pathways related to Prostate Cancer, Progression of according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
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9.1PTEN, EPHB2
29.1PTEN, EPHB2

Compounds for genes affiliated with Prostate Cancer, Progression of

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44Novoseek
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Compounds related to Prostate Cancer, Progression of according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1pd 98,059449.1PTEN, EPHB2
2phosphatidylinositol449.1PTEN, EPHB2
3phosphoinositide449.0PTEN, EPHB2
4arginine448.8PTEN, EPHB2

GO Terms for genes affiliated with Prostate Cancer, Progression of

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16Gene Ontology
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Biological processes related to Prostate Cancer, Progression of according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1angiogenesisGO:0015259.1PTEN, EPHB2
2dendritic spine morphogenesisGO:0609979.0PTEN, EPHB2
3negative regulation of axonogenesisGO:0507718.8PTEN, EPHB2

Products for genes affiliated with Prostate Cancer, Progression of

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Prostate Cancer, Progression of

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet