MCID: PRS022
MIFTS: 27

Prostate Leiomyoma malady

Summaries for Prostate Leiomyoma

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32MalaCards
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MalaCards: Prostate Leiomyoma, also known as prostatic leiomyoma, is related to leiomyoma and prostatitis. An important gene associated with Prostate Leiomyoma is DES (desmin), and among its related pathways are Cytoskeletal Signaling and Cytoskeleton remodeling Neurofilaments. The compounds orcein and s 100 have been mentioned in the context of this disorder. Affiliated tissues include prostate.

Aliases & Classifications for Prostate Leiomyoma

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8Disease Ontology, 60UMLS, 39NCIt
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Aliases & Descriptions:

prostate leiomyoma 8 60
prostatic leiomyoma 8


External Ids:

Disease Ontology8 DOID:2887
NCIt39 C5544

Related Diseases for Prostate Leiomyoma

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17GeneCards, 18GeneDecks
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Diseases related to Prostate Leiomyoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 47)
idRelated DiseaseScoreTop Affiliating Genes
1leiomyoma30.5DES, VIM
2prostatitis10.3
3adenomatoid tumor10.0VIM
4myoepithelioma10.0VIM
5perineurioma10.0VIM
6angiosarcoma10.0VIM
7infantile myofibromatosis10.0DES
8epidermolysis bullosa simplex10.0DES
9lymphangioleiomyomatosis10.0DES
10lipoma10.0DES
11medulloblastoma10.0DES
12epithelioid leiomyosarcoma10.0DES, VIM
13mesenchymal chondrosarcoma10.0VIM, DES
14pseudosarcomatous fibromatosis10.0DES, VIM
15spindle cell carcinoma10.0VIM, DES
16alveolar soft part sarcoma10.0DES, VIM
17spindle cell sarcoma10.0DES, VIM
18fibrous histiocytoma10.0DES, VIM
19endometrial stromal sarcoma10.0DES, VIM
20sex cord-gonadal stromal tumor10.0VIM, DES
21malignant mixed mullerian tumor10.0VIM, DES
22glomus tumor10.0DES, VIM
23abrikosov's tumor10.0VIM, DES
24giant cell tumor10.0VIM, DES
25sertoli cell tumor10.0DES, VIM
26malignant fibroxanthoma10.0VIM, DES
27pleomorphic adenoma10.0VIM, DES
28dermatofibrosarcoma protuberans10.0DES, VIM
29granular cell tumor10.0DES, VIM
30synovial sarcoma10.0DES, VIM
31hemangiopericytoma10.0VIM, DES
32smooth muscle tumor10.0DES, VIM
33neurilemmoma10.0DES, VIM
34angiomyolipoma10.0VIM, DES
35benign mesothelioma10.0DES, VIM
36fibromatosis10.0DES, VIM
37rhabdoid tumor10.0DES, VIM
38peripheral primitive neuroectodermal tumor10.0DES, VIM
39chordoma10.0DES, VIM
40leiomyosarcoma10.0DES, VIM
41liposarcoma10.0DES, VIM
42gastrointestinal stromal tumor10.0DES, VIM
43malignant mesothelioma10.0VIM, DES
44chondrosarcoma10.0DES, VIM
45fibrosarcoma10.0DES, VIM
46wilms tumor10.0VIM, DES
47rhabdomyosarcoma10.0DES, VIM

Graphical network of the top 20 diseases related to Prostate Leiomyoma:



Diseases related to prostate leiomyoma

Clinical Features for Prostate Leiomyoma

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Drugs & Therapeutics for Prostate Leiomyoma

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Prostate Leiomyoma

Drug clinical trials:

Search ClinicalTrials for Prostate Leiomyoma

Search NIH Clinical Center for Prostate Leiomyoma

Search CenterWatch for Prostate Leiomyoma

Genetic Tests for Prostate Leiomyoma

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Anatomical Context for Prostate Leiomyoma

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32MalaCards
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MalaCards organs/tissues related to Prostate Leiomyoma:

32
Prostate

Animal Models for Prostate Leiomyoma or affiliated genes

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Publications for Prostate Leiomyoma

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50PubMed
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Articles related to Prostate Leiomyoma:

idTitleAuthorsYear
1
Difficulty in the intravesical morcellation procedure for leiomyoma of the prostate enucleated by HoLEP. (23966460)
2013
2
A rare prostatic diagnosis of an old man: a pure prostatic leiomyoma. (24058741)
2013
3
Prostatic leiomyoma: a case report. (23198266)
2012
4
Prostatic leiomyoma. Case report. (21965262)
2011
5
Prostatic leiomyoma with atypia: follow-up study of 10 cases. (18774494)
2008
6
A huge 'prostate-mimicking' vaginal leiomyoma with simultaneous expression of oestrogen and progesterone receptors. (16953866)
2006
7
Bizarre leiomyoma of the prostate. (9126110)
1997
8
Epithelioid leiomyoma of the prostate. (8854080)
1996
9
Bizarre leiomyoma of the prostate. (3125678)
1988
10
Benign prostatic hypertrophy and uterine leiomyomas: analogous or dissimilar diseases? (6201884)
1984

Genetic Variations for Prostate Leiomyoma

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Expression for genes affiliated with Prostate Leiomyoma

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Prostate Leiomyoma

Search GEO for disease gene expression data for Prostate Leiomyoma.

Pathways for genes affiliated with Prostate Leiomyoma

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Sources:
4Cell Signaling Technology, 12EMD Millipore, 37NCBI BioSystems Database, 53Reactome
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Pathways related to Prostate Leiomyoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1DES, VIM
2
Hide members
9.1DES, VIM
3
Hide members
9.1DES, VIM
49.1DES, VIM

Compounds for genes affiliated with Prostate Leiomyoma

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Sources:
44Novoseek, 28IUPHAR, 11DrugBank, 24HMDB, 49PharmGKB, 2BitterDB
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Compounds related to Prostate Leiomyoma according to GeneCards/GeneDecks:

(show all 33)
idCompoundScoreTop Affiliating Genes
1orcein449.5DES, VIM
2s 100449.5DES, VIM
3toluidine449.5DES, VIM
4reticulin449.5DES, VIM
5mucicarmine449.5VIM, DES
6phalloidin449.5DES, VIM
7b 723449.5DES, VIM
8gemfibrozil44 28 1111.5DES, VIM
9bezafibrate44 28 1111.5VIM, DES
10acetaldehyde44 28 2411.5DES, VIM
11fenofibrate44 49 1111.5DES, VIM
12hematoxylin449.5DES, VIM
13ganglioside449.5VIM, DES
14procollagen449.5DES, VIM
15progestin449.5DES, VIM
16azathioprine44 49 2 1112.5DES, VIM
17biotin44 11 2411.4VIM, DES
18adriamycin449.4DES, VIM
19bromodeoxyuridine449.4DES, VIM
20dihydrotestosterone44 28 11 2412.4DES, VIM
21hyaluronic acid44 2410.4VIM, DES
22formaldehyde44 2410.4DES, VIM
23heparan sulfate44 2410.4DES, VIM
2412-o-tetradecanoylphorbol 13-acetate449.4DES, VIM
25methionine449.3VIM, DES
26doxorubicin44 49 1111.3DES, VIM
27glycogen44 2410.3DES, VIM
28actinomycin d449.2DES, VIM
29estradiol44 11 2411.2VIM, DES
30paraffin449.1DES, VIM
31lysine449.1DES, VIM
32proline449.0DES, VIM
33iron44 249.8DES, VIM

GO Terms for genes affiliated with Prostate Leiomyoma

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16Gene Ontology
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Cellular components related to Prostate Leiomyoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:0058829.1DES, VIM

Biological processes related to Prostate Leiomyoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1muscle filament slidingGO:0300499.1DES, VIM

Molecular functions related to Prostate Leiomyoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of cytoskeletonGO:0052009.1DES, VIM

Products for genes affiliated with Prostate Leiomyoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Prostate Leiomyoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet