MCID: PRS043
MIFTS: 30

Prostate Rhabdomyosarcoma malady

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Prostate Rhabdomyosarcoma

Aliases & Descriptions for Prostate Rhabdomyosarcoma:

Name: Prostate Rhabdomyosarcoma 12 14 69
Rhabdomyosarcoma of the Prostate 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3252
NCIt 47 C5522
UMLS 69 C1335518

Summaries for Prostate Rhabdomyosarcoma

Disease Ontology : 12 A rhabdomyosarcoma and sarcoma of prostate that is located in the prostate.

MalaCards based summary : Prostate Rhabdomyosarcoma, also known as rhabdomyosarcoma of the prostate, is related to prostate embryonal rhabdomyosarcoma and rhabdomyosarcoma. An important gene associated with Prostate Rhabdomyosarcoma is CKB (Creatine Kinase B), and among its related pathways/superpathways are Pathways in cancer and C-MYB transcription factor network. The drugs Liver Extracts and Vaccines have been mentioned in the context of this disorder. Affiliated tissues include prostate and the prostate, and related phenotype is Decreased human cytomegalovirus (HCMV) strain AD169 replication.

Related Diseases for Prostate Rhabdomyosarcoma

Graphical network of the top 20 diseases related to Prostate Rhabdomyosarcoma:



Diseases related to Prostate Rhabdomyosarcoma

Symptoms & Phenotypes for Prostate Rhabdomyosarcoma

GenomeRNAi Phenotypes related to Prostate Rhabdomyosarcoma according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased human cytomegalovirus (HCMV) strain AD169 replication GR00248-A 8.92 CKB CKM CKMT1B CKMT2

Drugs & Therapeutics for Prostate Rhabdomyosarcoma

Drugs for Prostate Rhabdomyosarcoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 8)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Liver Extracts Phase 1
2 Vaccines Phase 1
3 Cola Nutraceutical Phase 1
4
Cyclophosphamide Approved, Investigational 50-18-0, 6055-19-2 2907
5 Alkylating Agents
6 Immunosuppressive Agents
7 Antirheumatic Agents
8 Antineoplastic Agents, Alkylating

Interventional clinical trials:


id Name Status NCT ID Phase
1 Irradiated Donor Lymphocyte Infusion in Treating Patients With Relapsed or Refractory Hematologic Cancer or Solid Tumor Completed NCT00161187 Phase 1
2 Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial Cancer Unknown status NCT00499733

Search NIH Clinical Center for Prostate Rhabdomyosarcoma

Genetic Tests for Prostate Rhabdomyosarcoma

Anatomical Context for Prostate Rhabdomyosarcoma

MalaCards organs/tissues related to Prostate Rhabdomyosarcoma:

39
Prostate

The Foundational Model of Anatomy Ontology organs/tissues related to Prostate Rhabdomyosarcoma:

18
The Prostate

Publications for Prostate Rhabdomyosarcoma

Articles related to Prostate Rhabdomyosarcoma:

(show all 25)
id Title Authors Year
1
Current standards of care in bladder and prostate rhabdomyosarcoma. ( 26776454 )
2016
2
Quality of life and functional outcome of male patients with bladder-prostate rhabdomyosarcoma treated with conservative surgery and brachytherapy during childhood. ( 26895712 )
2016
3
Improvements in the Treatment of Patients Suffering from Bladder-Prostate Rhabdomyosarcoma: A Report from the CWS-2002P Trial. ( 27387676 )
2016
4
Prognostic factors in children undergoing salvage surgery for bladder/prostate rhabdomyosarcoma. ( 27255731 )
2016
5
Contrast-enhanced ultrasound aids in the detection of prostate rhabdomyosarcoma: A case report and literature review. ( 26622705 )
2015
6
A review on surgical techniques and organ sparing procedures in bladder/prostate rhabdomyosarcoma. ( 25486411 )
2014
7
Editorial comment on: The surgical management of paediatric bladder and prostate rhabdomyosarcoma. ( 26579244 )
2013
8
The surgical management of paediatric bladder and prostate rhabdomyosarcoma. ( 26579243 )
2013
9
What is the evidence for radical surgery in the management of localized embryonal bladder/prostate rhabdomyosarcoma? ( 22287287 )
2012
10
Comparison of different adjuvant radiotherapy approaches in childhood bladder/prostate rhabdomyosarcoma treated with conservative surgery. ( 22037652 )
2011
11
Treatment efficiency, outcome and surgical treatment problems in patients suffering from localized embryonal bladder/prostate rhabdomyosarcoma: a report from the Cooperative Soft Tissue Sarcoma trial CWS-96. ( 21370402 )
2011
12
Proton radiotherapy for pediatric bladder/prostate rhabdomyosarcoma: clinical outcomes and dosimetry compared to intensity-modulated radiation therapy. ( 20934266 )
2011
13
Symphysiotomy: a valuable approach in children with prostate rhabdomyosarcoma. ( 19904545 )
2010
14
Bladder/prostate rhabdomyosarcoma: past, present and future. ( 16952614 )
2006
15
Significance of persistent mature rhabdomyoblasts in bladder/prostate rhabdomyosarcoma: Results from IRS IV. ( 17006261 )
2006
16
Bladder/prostate rhabdomyosarcoma: miles to go before we sleep. ( 16952611 )
2006
17
Does the less aggressive multimodal approach of treating bladder-prostate rhabdomyosarcoma preserve bladder function? ( 16280839 )
2005
18
Does bladder preservation (as a surgical principle) lead to retaining bladder function in bladder/prostate rhabdomyosarcoma? Results from intergroup rhabdomyosarcoma study iv. ( 15126860 )
2004
19
Re: Does bladder preservation (as a surgical principle) lead to retaining bladder function in bladder/prostate rhabdomyosarcoma? Results from Intergroup Rhabdomyosarcoma Study IV. ( 15540797 )
2004
20
Treatment modalities of bladder/prostate rhabdomyosarcoma: a review. ( 12806368 )
2003
21
Post-chemotherapy microscopic residual prostate rhabdomyosarcoma: long-term conservative follow-up. ( 11793070 )
2002
22
Prostate rhabdomyosarcoma in a young adult: a case study. ( 9278381 )
1997
23
Bladder/prostate rhabdomyosarcoma: results of the multi-institutional trials of the Intergroup Rhabdomyosarcoma Study. ( 8284571 )
1993
24
Conservative surgery of bladder-prostate rhabdomyosarcoma in children: results after long-term follow-up. ( 8229587 )
1993
25
Prognostic factors in bladder and bladder-prostate rhabdomyosarcoma. ( 2262860 )
1990

Variations for Prostate Rhabdomyosarcoma

Expression for Prostate Rhabdomyosarcoma

Search GEO for disease gene expression data for Prostate Rhabdomyosarcoma.

Pathways for Prostate Rhabdomyosarcoma

GO Terms for Prostate Rhabdomyosarcoma

Biological processes related to Prostate Rhabdomyosarcoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 phosphorylation GO:0016310 9.43 CKB CKM CKMT1A CKMT1B CKMT2 KIT
2 creatine metabolic process GO:0006600 9.02 CKB CKM CKMT1A CKMT1B CKMT2

Molecular functions related to Prostate Rhabdomyosarcoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 transferase activity GO:0016740 9.85 CKB CKM CKMT1A CKMT1B CKMT2 KIT
2 ATP binding GO:0005524 9.8 CKB CKM CKMT1A CKMT1B CKMT2 KIT
3 catalytic activity GO:0003824 9.65 CKB CKM CKMT1A CKMT1B CKMT2
4 kinase activity GO:0016301 9.63 CKB CKM CKMT1A CKMT1B CKMT2 KIT
5 endopeptidase activity GO:0004175 9.4 KLK3 MMP1
6 transferase activity, transferring phosphorus-containing groups GO:0016772 9.35 CKB CKM CKMT1A CKMT1B CKMT2
7 creatine kinase activity GO:0004111 9.02 CKB CKM CKMT1A CKMT1B CKMT2

Sources for Prostate Rhabdomyosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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