MCID: PRS045
MIFTS: 38

Prostatic Hypertrophy malady

Reproductive diseases category
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Summaries for Prostatic Hypertrophy

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Wikipedia:65 Benign prostatic hyperplasia (BPH), also called benign enlargement of the prostate (BEP),... more...

MalaCards based summary: Prostatic Hypertrophy, also known as benign prostatic hypertrophy, is related to prostatitis and prostate cancer. An important gene associated with Prostatic Hypertrophy is ACPP (acid phosphatase, prostate), and among its related pathways are Glioma and Regulation of Androgen receptor activity. The compounds provenge and estracyt have been mentioned in the context of this disorder. Affiliated tissues include prostate, heart and breast.

Aliases & Classifications for Prostatic Hypertrophy

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Prostatic Hypertrophy, Aliases & Descriptions:

Name: Prostatic Hypertrophy 8 10
 
Benign Prostatic Hypertrophy 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Reproductive diseases


External Ids:

Disease Ontology8 DOID:11132

Related Diseases for Prostatic Hypertrophy

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Graphical network of the top 20 diseases related to Prostatic Hypertrophy:



Diseases related to prostatic hypertrophy

Symptoms for Prostatic Hypertrophy

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Drugs & Therapeutics for Prostatic Hypertrophy

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Drug clinical trials:

Search ClinicalTrials for Prostatic Hypertrophy

Search NIH Clinical Center for Prostatic Hypertrophy

Genetic Tests for Prostatic Hypertrophy

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Anatomical Context for Prostatic Hypertrophy

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MalaCards organs/tissues related to Prostatic Hypertrophy:

32
Prostate, Heart, Breast, Bone, Smooth muscle, Colon, Kidney, Appendix

Animal Models for Prostatic Hypertrophy or affiliated genes

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Publications for Prostatic Hypertrophy

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Articles related to Prostatic Hypertrophy:

(show top 50)    (show all 519)
idTitleAuthorsYear
1
Re: Editorial comment on constitutional, organopathic and combined homeopathic treatment of benign prostatic hypertrophy: a clinical trial: S. A. Kaplan J Urol 2013; 190: 1818-1819. (24892642)
2014
2
Tadalafil and benign prostatic hypertrophy. Too risky. (24860894)
2014
3
American Urological Association and European Association of Urology guidelines in the management of benign prostatic hypertrophy: revisited. (22123290)
2012
4
Testosterone levels in benign prostatic hypertrophy and prostate cancer. (18362481)
2008
5
Should patients with benign prostatic hypertrophy stop taking doxazosin in the light of the ALLHAT study? (16412808)
2006
6
Consensus conference about imaging of Benign Prostatic Hypertrophy. (16200040)
2005
7
Quality improvement activities in prostatectomy for benign prostatic hypertrophy. (12698520)
2003
8
Evidence-based meta-analysis of pharmacotherapy for benign prostatic hypertrophy. (12534901)
2002
9
Ammonium-chloride-induced prostatic hypertrophy in vitro: urinary ammonia as a potential risk factor for benign prostatic hyperplasia. (10550527)
1999
10
Construction and validation of a short-form benign prostatic hypertrophy health-related quality-of-life questionnaire. BPH Group in General Practice. (9393292)
1997
11
Detection of bladder tumor by urine cytology in cases of prostatic hypertrophy. (8989544)
1996
12
Laser ablation of prostatic hypertrophy. (7544883)
1995
13
Microwave hyperthermia in benign prostatic hypertrophy: a controlled clinical trial. (7544207)
1995
14
Objective noninvasive evaluation of benign prostatic hypertrophy. (7535622)
1995
15
Short-term oral treatment of canine benign prostatic hypertrophy with chlormadinone acetate. (7538794)
1995
16
Benign prostatic hypertrophy. Options for management. (7518555)
1994
17
New treatments for benign prostatic hypertrophy. (7527259)
1994
18
Technology briefs from the Conseil d'Evaluation des Technologies de la SantAc du QuAcbec (CETS). Diathermy and balloon dialatation treatment of benign prostatic hypertrophy. (7507097)
1993
19
Minimally invasive therapy in bladder outflow obstruction due to benign prostatic hypertrophy. A review of prostatic balloon dilatation and stenting. (7689316)
1993
20
Tissue polypeptide-specific antigen: a discriminative parameter between prostate cancer and benign prostatic hypertrophy. (7679580)
1993
21
Urinary flow rate in benign prostatic hypertrophy in relation to the degree of obstruction of the vesical outlet. (1373665)
1992
22
Subjective and clinical results after transurethral resection and suprapubic prostatectomy in benign prostatic hypertrophy. (1726084)
1991
23
Dynamics of micturition in benign prostatic hypertrophy patients with compensated obstruction of the vesical outlet: a denervation supersensitivity-related energy-saving mechanism. (1719245)
1991
24
Endocrine treatment of benign prostatic hypertrophy: current concepts. (1702565)
1991
25
Prazosin: an evaluation of its clinical efficacy and safety in the treatment of benign prostatic hypertrophy. (1690475)
1990
26
Re: Bladder outflow tract obstruction and urinary retention from benign prostatic hypertrophy treated by balloon dilatation. (1699630)
1990
27
The effect of bromocriptine in benign prostatic hypertrophy and vesicosphincteric dynamics. (2444307)
1987
28
Development of benign prostatic hypertrophy estimated from ultrasonic measurement with long-term follow up. (2437669)
1987
29
Circulating levels of inhibin, prolactin, TSH, LH, and FSH in benign prostatic hypertrophy before and after tumor resection. (2436203)
1987
30
An objective comparison of transurethral resection and bladder neck incision in the treatment of prostatic hypertrophy. (6180189)
1982
31
Specific binding of [3H]-methyltrienolone to both progestin and androgen binding components in human benign prostatic hypertrophy (BPH). (88546)
1979
32
Serum dihydrotestosterone in patients with benign prostatic hypertrophy. (73397)
1977
33
Using antiandrogen therapy in benign prostatic hypertrophy. (66171)
1977
34
The effect of bromocriptine in patients with benign prostatic hypertrophy. (57815)
1976
35
Intracellular localisation of 5alpha-dihydrotestosterone in human benign prostatic hypertrophy. (63340)
1976
36
Urinary flow rate in benign prostatic hypertrophy. (56317)
1976
37
The effect of a 6FG urethral catheter on urinary flow in benign prostatic hypertrophy. (61185)
1976
38
In vivo uptake and metabolism of 3-h-5alpha-androstane-3alpha,17beta-diol and of 3-h-5alpha-androstane-3beta,17beta-diol by human prostatic hypertrophy. (49141)
1975
39
Flat epithelial changes in the urinary bladder in patients with prostatic hypertrophy. (4118752)
1972
40
Therapy with progestational agents in advanced benign prostatic hypertrophy. (4187537)
1969
41
Treatment of benign prostatic hypertrophy with progestational agents: a preliminary report. (4172531)
1968
42
Hypertension, diabetes mellitus, and blood groups in benign prostatic hypertrophy. (4143704)
1966
43
TREATMENT OF BENIGN PROSTATIC HYPERTROPHY WITH HYDROXYPROGESTERONE CAPROATE: EFFECT ON CLINICAL SYMPTOMS, MORPHOLOGY, AND ENDOCRINE FUNCTION. (14304354)
1965
44
VOIDING PRESSURE AND URINARY FLOW IN PROSTATIC HYPERTROPHY AND IN NEUROGENIC BLADDER DISORDERS. (14227133)
1964
45
Prostatic hypertrophy in Indonesia. (13919435)
1962
46
Sex chromatin in cells of prostatic hypertrophy and prostatic cancer. (13364266)
1956
47
Benign prostatic hypertrophy. (13346266)
1956
48
Transurethral, perineal, and retropubic prostatectomy; an analysis of 300 operations performed for the correction of benign prostatic hypertrophy. (14836118)
1951
49
Prostatic hypertrophy. (18148544)
1949
50
Benign prostatic hypertrophy, with obstruction. (18899249)
1948

Variations for Prostatic Hypertrophy

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Expression for genes affiliated with Prostatic Hypertrophy

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Expression patterns in normal tissues for genes affiliated with Prostatic Hypertrophy

Search GEO for disease gene expression data for Prostatic Hypertrophy.

Pathways for genes affiliated with Prostatic Hypertrophy

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Pathways related to Prostatic Hypertrophy according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Signaling Pathways in Glioblastoma37
9.4FGF8, KLK3
29.3KLK3, SRY

Compounds for genes affiliated with Prostatic Hypertrophy

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Sources:
44Novoseek, 28IUPHAR, 11DrugBank, 61Tocris Bioscience, 24HMDB
See all sources

Compounds related to Prostatic Hypertrophy according to GeneCards/GeneDecks:

(show all 29)
idCompoundScoreTop Affiliating Genes
1provenge449.9KLK3, ACPP
2estracyt449.9ACPP, KLK3
3chlormadinone acetate449.9ACPP, KLK3
4estramustine phosphate449.9ACPP, KLK3
5goserelin44 28 1111.8ACPP, KLK3
6nilutamide44 61 28 1112.8ACPP, KLK3
7buserelin44 28 1111.8ACPP, KLK3
8estramustine44 1110.8ACPP, KLK3
9finasteride44 61 24 1112.8KLK3, ACPP
10dtpa449.8KLK3, ACPP
11cyproteroneacetate449.8ACPP, KLK3
12flutamide44 61 1111.8KLK3, ACPP
13bicalutamide44 61 1111.8ACPP, KLK3
14diethylstilbestrol44 28 1111.7KLK3, ACPP
15dehydroepiandrosterone sulfate449.7KLK3, ACPP
16dhea449.7KLK3, ACPP
17gnrh449.5ACPP, KLK3
18biotin44 24 1111.4KLK3, SRY
19guanine44 24 1111.4KLK3, SRY
20suramin44 28 1111.3FGF8, KLK3, ACPP
21deoxyribonucleic acid449.3KLK3, ACPP, SRY
22dihydrotestosterone44 28 24 1112.2KLK3, ACPP, SRY
23vitamin d449.2KLK3, ACPP
24estradiol44 24 1111.2KLK3, ACPP, SRY
25steroid449.1SRY, ACPP, KLK3
26polysaccharide449.0KLK3, LGALS8
27zinc44 2410.0FGF8, ACPP, SRY
28serine448.9KLK3, ACPP, SRY
29testosterone44 61 24 1111.7SRY, ACPP, KLK3, FGF8

GO Terms for genes affiliated with Prostatic Hypertrophy

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Cellular components related to Prostatic Hypertrophy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056158.7FGF8, ACPP, LGALS8

Products for genes affiliated with Prostatic Hypertrophy

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  • Antibodies
  • Proteins
  • Lysates

Sources for Prostatic Hypertrophy

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet