MCID: PRS045
MIFTS: 37

Prostatic Hypertrophy malady

Reproductive diseases category

Summaries for Prostatic Hypertrophy

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Sources:
66Wikipedia, 34MalaCards
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Wikipedia:66 Benign prostatic hyperplasia (BPH), also called benign enlargement of the prostate (BEP),... more...

MalaCards: Prostatic Hypertrophy, also known as benign prostatic hypertrophy, is related to prostatitis and prostate cancer. An important gene associated with Prostatic Hypertrophy is ACPP (acid phosphatase, prostate), and among its related pathways are Glioma and Regulation of Androgen receptor activity. The compounds provenge and estracyt have been mentioned in the context of this disorder. Affiliated tissues include prostate, heart and breast.

Aliases & Classifications for Prostatic Hypertrophy

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Sources:
9Disease Ontology, 11DISEASES, 63UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Reproductive diseases


Aliases & Descriptions:

prostatic hypertrophy 9 11
benign prostatic hypertrophy 63


External Ids:

Disease Ontology9 DOID:11132

Related Diseases for Prostatic Hypertrophy

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Sources:
18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Prostatic Hypertrophy:



Diseases related to prostatic hypertrophy

Symptoms for Prostatic Hypertrophy

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Drugs & Therapeutics for Prostatic Hypertrophy

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Prostatic Hypertrophy

Drug clinical trials:

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Search NIH Clinical Center for Prostatic Hypertrophy

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Genetic Tests for Prostatic Hypertrophy

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Anatomical Context for Prostatic Hypertrophy

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Sources:
34MalaCards
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MalaCards organs/tissues related to Prostatic Hypertrophy:

34
Prostate, Heart, Breast, Bone, Smooth muscle, Colon, Kidney, Appendix

Animal Models for Prostatic Hypertrophy or affiliated genes

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Publications for Prostatic Hypertrophy

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Sources:
53PubMed
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Articles related to Prostatic Hypertrophy:

(show top 50)    (show all 506)
idTitleAuthorsYear
1
American Urological Association and European Association of Urology guidelines in the management of benign prostatic hypertrophy: revisited. (22123290)
2012
2
Management of benign prostatic hypertrophy-related urinary retention: current trends and perspectives. (20027550)
2009
3
Testosterone levels in benign prostatic hypertrophy and prostate cancer. (18362481)
2008
4
Should patients with benign prostatic hypertrophy stop taking doxazosin in the light of the ALLHAT study? (16412808)
2006
5
Consensus conference about imaging of Benign Prostatic Hypertrophy. (16200040)
2005
6
Quality improvement activities in prostatectomy for benign prostatic hypertrophy. (12698520)
2003
7
Evidence-based meta-analysis of pharmacotherapy for benign prostatic hypertrophy. (12534901)
2002
8
Ammonium-chloride-induced prostatic hypertrophy in vitro: urinary ammonia as a potential risk factor for benign prostatic hyperplasia. (10550527)
1999
9
Construction and validation of a short-form benign prostatic hypertrophy health-related quality-of-life questionnaire. BPH Group in General Practice. (9393292)
1997
10
Detection of bladder tumor by urine cytology in cases of prostatic hypertrophy. (8989544)
1996
11
Usefulness of PSA density and PSA excess in the differential diagnosis between prostate cancer and benign prostatic hypertrophy. (8740636)
1996
12
Laser ablation of prostatic hypertrophy. (7544883)
1995
13
Microwave hyperthermia in benign prostatic hypertrophy: a controlled clinical trial. (7544207)
1995
14
Objective noninvasive evaluation of benign prostatic hypertrophy. (7535622)
1995
15
Short-term oral treatment of canine benign prostatic hypertrophy with chlormadinone acetate. (7538794)
1995
16
Benign prostatic hypertrophy. Options for management. (7518555)
1994
17
New treatments for benign prostatic hypertrophy. (7527259)
1994
18
Technology briefs from the Conseil d'Evaluation des Technologies de la SantAc du QuAcbec (CETS). Diathermy and balloon dialatation treatment of benign prostatic hypertrophy. (7507097)
1993
19
Minimally invasive therapy in bladder outflow obstruction due to benign prostatic hypertrophy. A review of prostatic balloon dilatation and stenting. (7689316)
1993
20
Urinary flow rate in benign prostatic hypertrophy in relation to the degree of obstruction of the vesical outlet. (1373665)
1992
21
Subjective and clinical results after transurethral resection and suprapubic prostatectomy in benign prostatic hypertrophy. (1726084)
1991
22
Dynamics of micturition in benign prostatic hypertrophy patients with compensated obstruction of the vesical outlet: a denervation supersensitivity-related energy-saving mechanism. (1719245)
1991
23
Endocrine treatment of benign prostatic hypertrophy: current concepts. (1702565)
1991
24
Prazosin: an evaluation of its clinical efficacy and safety in the treatment of benign prostatic hypertrophy. (1690475)
1990
25
Re: Bladder outflow tract obstruction and urinary retention from benign prostatic hypertrophy treated by balloon dilatation. (1699630)
1990
26
The effect of bromocriptine in benign prostatic hypertrophy and vesicosphincteric dynamics. (2444307)
1987
27
Development of benign prostatic hypertrophy estimated from ultrasonic measurement with long-term follow up. (2437669)
1987
28
Circulating levels of inhibin, prolactin, TSH, LH, and FSH in benign prostatic hypertrophy before and after tumor resection. (2436203)
1987
29
An objective comparison of transurethral resection and bladder neck incision in the treatment of prostatic hypertrophy. (6180189)
1982
30
Specific binding of [3H]-methyltrienolone to both progestin and androgen binding components in human benign prostatic hypertrophy (BPH). (88546)
1979
31
Serum dihydrotestosterone in patients with benign prostatic hypertrophy. (73397)
1977
32
Using antiandrogen therapy in benign prostatic hypertrophy. (66171)
1977
33
The effect of bromocriptine in patients with benign prostatic hypertrophy. (57815)
1976
34
Correlations between clinical findings and urinary flow rate in benign prostatic hypertrophy. (61184)
1976
35
Urinary flow rate in benign prostatic hypertrophy. (56317)
1976
36
The effect of a 6FG urethral catheter on urinary flow in benign prostatic hypertrophy. (61185)
1976
37
Testosterone metabolism in benign prostatic hypertrophy: in vivo studies of gestonorone caproate and cyproterone acetate. (64267)
1976
38
In vivo uptake and metabolism of 3-h-5alpha-androstane-3alpha,17beta-diol and of 3-h-5alpha-androstane-3beta,17beta-diol by human prostatic hypertrophy. (49141)
1975
39
Flat epithelial changes in the urinary bladder in patients with prostatic hypertrophy. (4118752)
1972
40
Therapy with progestational agents in advanced benign prostatic hypertrophy. (4187537)
1969
41
Treatment of benign prostatic hypertrophy with progestational agents: a preliminary report. (4172531)
1968
42
Hypertension, diabetes mellitus, and blood groups in benign prostatic hypertrophy. (4143704)
1966
43
TREATMENT OF BENIGN PROSTATIC HYPERTROPHY WITH HYDROXYPROGESTERONE CAPROATE: EFFECT ON CLINICAL SYMPTOMS, MORPHOLOGY, AND ENDOCRINE FUNCTION. (14304354)
1965
44
VOIDING PRESSURE AND URINARY FLOW IN PROSTATIC HYPERTROPHY AND IN NEUROGENIC BLADDER DISORDERS. (14227133)
1964
45
Prostatic hypertrophy in Indonesia. (13919435)
1962
46
Sex chromatin in cells of prostatic hypertrophy and prostatic cancer. (13364266)
1956
47
Benign prostatic hypertrophy. (13346266)
1956
48
Transurethral, perineal, and retropubic prostatectomy; an analysis of 300 operations performed for the correction of benign prostatic hypertrophy. (14836118)
1951
49
Prostatic hypertrophy. (18148544)
1949
50
Benign prostatic hypertrophy, with obstruction. (18899249)
1948

Variations for Prostatic Hypertrophy

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Expression for genes affiliated with Prostatic Hypertrophy

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Prostatic Hypertrophy

Search GEO for disease gene expression data for Prostatic Hypertrophy.

Pathways for genes affiliated with Prostatic Hypertrophy

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Sources:
51PathCards, 31KEGG, 39NCBI BioSystems Database
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Pathways related to Prostatic Hypertrophy according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Signaling Pathways in Glioblastoma39
9.4FGF8, KLK3
29.3KLK3, SRY

Compounds for genes affiliated with Prostatic Hypertrophy

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Sources:
46Novoseek, 30IUPHAR, 12DrugBank, 62Tocris Bioscience, 25HMDB
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Compounds related to Prostatic Hypertrophy according to GeneCards/GeneDecks:

(show all 29)
idCompoundScoreTop Affiliating Genes
1provenge469.9KLK3, ACPP
2estracyt469.9ACPP, KLK3
3chlormadinone acetate469.9ACPP, KLK3
4estramustine phosphate469.9ACPP, KLK3
5goserelin46 30 1211.8ACPP, KLK3
6nilutamide46 62 30 1212.8ACPP, KLK3
7buserelin46 30 1211.8ACPP, KLK3
8estramustine46 1210.8ACPP, KLK3
9finasteride46 62 25 1212.8KLK3, ACPP
10dtpa469.8KLK3, ACPP
11cyproteroneacetate469.8ACPP, KLK3
12flutamide46 62 1211.8KLK3, ACPP
13bicalutamide46 62 1211.8ACPP, KLK3
14diethylstilbestrol46 30 1211.7KLK3, ACPP
15dehydroepiandrosterone sulfate469.7KLK3, ACPP
16dhea469.7KLK3, ACPP
17gnrh469.5ACPP, KLK3
18biotin46 25 1211.4KLK3, SRY
19guanine46 25 1211.4KLK3, SRY
20suramin46 30 1211.3FGF8, KLK3, ACPP
21deoxyribonucleic acid469.3KLK3, ACPP, SRY
22dihydrotestosterone46 30 25 1212.2KLK3, ACPP, SRY
23vitamin d469.2KLK3, ACPP
24estradiol46 25 1211.2KLK3, ACPP, SRY
25steroid469.1SRY, ACPP, KLK3
26polysaccharide469.0KLK3, LGALS8
27zinc46 2510.0FGF8, ACPP, SRY
28serine468.9KLK3, ACPP, SRY
29testosterone46 62 25 1211.7SRY, ACPP, KLK3, FGF8

GO Terms for genes affiliated with Prostatic Hypertrophy

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Sources:
17Gene Ontology
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Cellular components related to Prostatic Hypertrophy according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056158.7FGF8, ACPP, LGALS8

Products for genes affiliated with Prostatic Hypertrophy

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Prostatic Hypertrophy

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet