MCID: PRS047
MIFTS: 50

Prostatitis malady

Summaries for Prostatitis

Sources:
64Wikipedia, 33MalaCards
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Wikipedia:64 Prostatitis (less commonly prostatosis) is inflammation of the prostate gland. Prostatitis is classified... more...

MalaCards: Prostatitis is related to adenocarcinoma and prostatic adenoma. An important gene associated with Prostatitis is FOLH1 (folate hydrolase (prostate-specific membrane antigen) 1), and among its related pathways are Coregulation of Androgen receptor activity and Regulation of Androgen receptor activity. The drugs ciprofloxacin and norfloxacin and the compounds testosterone and dihydrotestosterone have been mentioned in the context of this disorder.

Aliases & Classifications for Prostatitis

Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 61UMLS, 35MeSH, 40NCIt, 57SNOMED-CT, 27ICD9CM
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Aliases & Descriptions:

prostatitis 8 10 45 61


External Ids:

Disease Ontology8 DOID:14654
MeSH35 D011472
NCIt40 C26866
ICD9CM27 601.9, 601

Related Diseases for Prostatitis

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Prostatitis:



Diseases related to prostatitis

Clinical Features for Prostatitis

Drugs & Therapeutics for Prostatitis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

Search CenterWatch for Prostatitis

Drug clinical trials:

Search ClinicalTrials for Prostatitis

Search NIH Clinical Center for Prostatitis

Search CenterWatch for Prostatitis

Inferred drug relations via UMLS61/NDF-RT41:

Genetic Tests for Prostatitis

Anatomical Context for Prostatitis

Animal Models for Prostatitis or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Prostatitis

Sources:
51PubMed
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Articles related to Prostatitis:

(show top 50)    (show all 616)
idTitleAuthorsYear
1
Can mean platelet volume serve as a marker for prostatitis? (23983600)
2013
2
Do the medical treatment reduces the rate of surgical treatment in suspected cases of chronic prostatitis before prostatectomy? (23329532)
2013
3
Classification and treatment of men with chronic prostatitis/chronic pelvic pain syndrome using the UPOINT system. (23588814)
2013
4
Pseudomonas aeruginosa bacteremia and prostatitis in a patient with cystic fibrosis. (23401732)
2013
5
Anal stretching device for patients with chronic prostatitis and chronic pelvic pain syndrome]. (23589597)
2013
6
The role of National Institutes of Health category IV prostatitis in accurately staging the newly diagnosed prostate cancer. (23370973)
2013
7
Diagnosis and follow-up of chronic bacterial prostatitis with recurrent urinary tract infection detected by 67Ga scintigraphy and SPECT/CT. (24089068)
2013
8
PCR for diagnosis of male Trichomonas vaginalis infection with chronic prostatitis and urethritis. (22711929)
2012
9
The effects of transrectal radiofrequency hyperthermia on patients with chronic prostatitis and the changes of MDA, NO, SOD, and Zn levels in pretreatment and posttreatment. (22100490)
2012
10
Transabdominal ultrasound measurement of pelvic floor muscle mobility in men with and without chronic prostatitis/chronic pelvic pain syndrome. (22925244)
2012
11
Topographic and quantitative relationship between prostate inflammation, proliferative inflammatory atrophy and low-grade prostate intraepithelial neoplasia: a biopsy study in chronic prostatitis patients. (23026863)
2012
12
Characterisation of the bacterial community in expressed prostatic secretions from patients with chronic prostatitis/chronic pelvic pain syndrome and infertile men: a preliminary investigation. (22635162)
2012
13
JAMA patient page. Prostatitis. (22298682)
2012
14
Fluoroquinolone-resistant acute prostatitis requiring hospitalization after transrectal prostate biopsy: effect of previous fluoroquinolone use as prophylaxis or long-term treatment. (21547465)
2012
15
Prostate Cancer Can Be Detected Even in Patients with Decreased PSA Less than 2.5 ng/ml after Treatment of Chronic Prostatitis. (21860765)
2011
16
Dutasteride reduces prostatitis symptoms compared with placebo in men enrolled in the REDUCE study. (21849186)
2011
17
The correlation of extent and grade of inflammation with serum PSA levels in patients with IV prostatitis. (20820917)
2011
18
Use of the UPOINT chronic prostatitis/chronic pelvic pain syndrome classification in European patient cohorts: sexual function domain improves correlations. (20952019)
2010
19
Crucial role of interferon-gamma in experimental autoimmune prostatitis. (20096883)
2010
20
Cytomegalovirus prostatitis: a series of 4 cases. (18701513)
2010
21
Chronic bacterial prostatitis detected by FDG PET/CT in a patient presented with fever of unknown origin. (20940554)
2010
22
Treatment of bacterial prostatitis. (20459324)
2010
23
Color Doppler ultrasonographic scanning in acute bacterial prostatitis. (21341580)
2010
24
Re: Alfuzosin and symptoms of chronic prostatitis-chronic pelvic pain syndrome. (19691138)
2009
25
Fluoroquinolone treatment of chronic bacterial prostatitis: a prospective cohort study. (19567353)
2009
26
An aberrant prostate antigen-specific immune response causes prostatitis in mice and is associated with chronic prostatitis in humans. (19603556)
2009
27
Re: Stancik et al: Effect of antibiotic therapy on interleukin-6 in fresh semen and postmasturbation urine samples of patients with chronic prostatitis/chronic pelvic pain syndrome. (Urology 2008;72: 336-339). (19482170)
2009
28
The evaluation of markers of prostatic inflammation and function of the prostate gland in patients with chronic prostatitis. (18661262)
2008
29
ZapA, a virulence factor in a rat model of Proteus mirabilis-induced acute and chronic prostatitis. (18725420)
2008
30
Treatment for chronic prostatitis/chronic pelvic pain syndrome: levofloxacin, doxazosin and their combination. (18362485)
2008
31
Acute bacterial prostatitis after transrectal prostate needle biopsy: clinical analysis. (18297448)
2008
32
Evaluation of normal prostate tissue, chronic prostatitis, and prostate cancer by quantitative perfusion analysis using a dynamic contrast-enhanced inversion-prepared dual-contrast gradient echo sequence. (18580330)
2008
33
Prostate cancer and chronic prostatitis. (18765133)
2008
34
Value of antibiotic therapy for bioptically proved chronic prostatitis. (18447263)
2008
35
Evaluation of prostatitis in autopsied prostates--is chronic inflammation more associated with benign prostatic hyperplasia or cancer? (18343414)
2008
36
Diagnosis of acute bacterial prostatitis by Ga-67 scintigraphy and SPECT-CT. (18936626)
2008
37
Diffuse FDG uptake in acute prostatitis. (18356681)
2008
38
Effect of chronic prostatitis on angiogenic activity and serum prostate specific antigen level in benign prostatic hyperplasia. (17666305)
2007
39
An overview of prostatitis. Compliance can be biggest challenge. (19998980)
2007
40
Prevalence, incidence estimation, risk factors and characterization of chronic prostatitis/chronic pelvic pain syndrome in urological hospital outpatients in Italy: results of a multicenter case-control observational study. (17937946)
2007
41
Cryptococcal prostatitis and osteomyelitis. (17557526)
2007
42
Autoimmune prostatitis: state of the art. (17635799)
2007
43
Effects of antibiotic and anti-inflammatory treatment on serum PSA and free PSA levels in patients with chronic prostatitis IIIA]. (17009527)
2006
44
Increased oxidative stress and oxidative damage associated with chronic bacterial prostatitis. (16625281)
2006
45
Reduced semen quality in chronic prostatitis patients that have cellular autoimmune response to prostate antigens. (15890732)
2005
46
PSA decrease after levofloxacin therapy in patients with histological prostatitis. (15693428)
2004
47
Nonbacterial prostatitis caused by partial urethral obstruction in the rat. (10550522)
1999
48
Tuberculous epididymo-orchitis and granulomatous prostatitis mimicking neoplasia. (2126830)
1990
49
The differential diagnosis of allergic prostatitis]. (1973316)
1990
50
THE A8TIOLOGY, DIAGNOSIS AND TREATMENT OF CHRONIC PROSTATITIS AND SEMINAL VESICULITIS. (21773462)
1930

Genetic Variations for Prostatitis

Expression for genes affiliated with Prostatitis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Prostatitis

Search GEO for disease gene expression data for Prostatitis.

Pathways for genes affiliated with Prostatitis

Sources:
38NCBI BioSystems Database, 54Reactome
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Pathways related to Prostatitis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
111.3PAWR, KLK3, KLK2
211.3SPDEF, KLK3, KLK2
311.0KLK3, KLK2

Compounds for genes affiliated with Prostatitis

Sources:
45Novoseek, 60Tocris Bioscience, 11DrugBank, 24HMDB, 29IUPHAR
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Compounds related to Prostatitis according to GeneCards/GeneDecks:

(show all 15)
idCompoundScoreTop Affiliating Genes
1testosterone45 60 11 2415.3KLK2, KLK3, FOLH1, ACPP, MSMB, SPDEF
2dihydrotestosterone45 29 11 2415.1SPDEF, ACPP, FOLH1, KLK3, KLK2
3prostascint4511.3KLK3, FOLH1
4provenge4511.3ACPP, KLK3
5heme29 11 2413.3STEAP4, STEAP2, STEAP1
6estracyt4511.3ACPP, KLK3
7chlormadinone acetate4511.2ACPP, KLK3
8estramustine phosphate4511.2KLK3, ACPP
9goserelin45 29 1113.2ACPP, KLK3
10nilutamide45 60 29 1114.2ACPP, KLK3
11buserelin45 29 1113.1KLK3, ACPP
12estramustine45 1112.1KLK3, ACPP
13finasteride45 60 11 2414.0KLK3, ACPP
14dtpa4510.9ACPP, KLK3
15cyproteroneacetate4510.7ACPP, KLK3

GO Terms for genes affiliated with Prostatitis

Products for genes affiliated with Prostatitis

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  • Lysates
  • Antibodies

Sources for Prostatitis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet