PEM
MCID: PRT038
MIFTS: 48

Protein-Energy Malnutrition (PEM) malady

Metabolic diseases category
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Summaries for Protein-Energy Malnutrition

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Wikipedia:65 Protein?energy malnutrition (PEM) or protein?calorie malnutrition refers to a form of malnutrition where... more...

MalaCards based summary: Protein-Energy Malnutrition, also known as PEM, is related to liver cirrhosis and hepatitis. An important gene associated with Protein-Energy Malnutrition is PIGR (polymeric immunoglobulin receptor), and among its related pathways are Diseases associated with visual transduction and Visual Cycle in Retinal Rods. The compounds styrene and purpurin have been mentioned in the context of this disorder. Affiliated tissues include bone, liver and brain, and related mouse phenotype homeostasis/metabolism.

Aliases & Classifications for Protein-Energy Malnutrition

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Protein-Energy Malnutrition, Aliases & Descriptions:

Name: Protein-Energy Malnutrition 8 10 44 62
 
Pem 38


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Metabolic diseases


External Ids:

Disease Ontology8 DOID:11801
ICD9CM27 263.9
MeSH34 D011502
NCIt39 C34952
ICD1025 E46

Related Diseases for Protein-Energy Malnutrition

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Graphical network of the top 20 diseases related to Protein-Energy Malnutrition:



Diseases related to protein-energy malnutrition

Symptoms for Protein-Energy Malnutrition

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Drugs & Therapeutics for Protein-Energy Malnutrition

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Drug clinical trials:

Search ClinicalTrials for Protein-Energy Malnutrition

Search NIH Clinical Center for Protein-Energy Malnutrition

Genetic Tests for Protein-Energy Malnutrition

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Anatomical Context for Protein-Energy Malnutrition

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MalaCards organs/tissues related to Protein-Energy Malnutrition:

32
Bone, Liver, Brain, Testes, Thyroid, Bone marrow, Small intestine, Thymus, Heart, Skeletal muscle, Kidney, Skin, T cells, B cells, Colon, Pancreas, Placenta, Monocytes, Pituitary, Neutrophil

Animal Models for Protein-Energy Malnutrition or affiliated genes

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MGI Mouse Phenotypes related to Protein-Energy Malnutrition:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053767.5RBP4, CCK, EPHX1, TTR, PIGR

Publications for Protein-Energy Malnutrition

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Articles related to Protein-Energy Malnutrition:

(show top 50)    (show all 509)
idTitleAuthorsYear
1
Prevalence of protein-energy malnutrition in hospital patients over 75 years of age admitted for hip fracture. (24998085)
2014
2
Cystic fibrosis: from protein-energy malnutrition to obesity with dyslipidemia. (24800027)
2013
3
A narrative review of recent progress in understanding the relationship between tuberculosis and protein energy malnutrition. (23942176)
2013
4
Protein-energy malnutrition alters IgA responses to rotavirus vaccination and infection but does not impair vaccine efficacy in mice. (24200975)
2013
5
Hepatoprotective and nephroprotective effects of Cnidoscolus aconitifolius in protein energy malnutrition induced liver and kidney damage. (24174819)
2013
6
Evaluating risk factors for protein-energy malnutrition in children under the age of six years: a case-control study from Iran. (21887115)
2011
7
Protein-energy malnutrition alters hippocampal plasticity-associated protein expression following global ischemia in the gerbil. (20883206)
2010
8
Study of lymphocyte subpopulations in bone marrow in a model of protein-energy malnutrition. (20036516)
2010
9
Serum ghrelin in infants with protein-energy malnutrition. (19261361)
2009
10
Serum ghrelin levels in children with primary protein-energy malnutrition. (18937750)
2008
11
Current prevalence and predictors of protein-energy malnutrition among schoolchildren in rural Peninsular Malaysia. (19058591)
2008
12
Effect of protein-energy malnutrition on erythropoietin requirement in maintenance hemodialysis patients. (17403171)
2007
13
Protein-energy malnutrition alters histological and ultrastructural characteristics of the bone marrow and decreases haematopoiesis in adult mice. (17357095)
2007
14
Pancreatic size in protein energy malnutrition: a predictor of nutritional recovery. (15536474)
2005
15
Detection of severe protein-energy malnutrition by nurses in The Gambia. (14736639)
2004
16
An evaluation of re-orientation training program of ICDS functionaries on protein-energy malnutrition. (11439866)
2000
17
Micronutrient deficiencies and protein-energy malnutrition. (9635975)
1998
18
Effects of protein-energy malnutrition on muscarinic receptor density and acetylcholinesterase activity in rat brain. (9195001)
1997
19
Vitamin E status in protein energy malnutrition. (23100878)
1997
20
Correction of protein-energy malnutrition in older adults: effects of a short-term aerobic training program. (16844611)
1997
21
Profile of protein energy malnutrition amongst children under four years in urban areas of Rivers State. (8652441)
1996
22
The clinical assessment of adult patients with protein energy malnutrition. (7659057)
1995
23
The computed axial tomography of the brain in protein energy malnutrition. (8687211)
1995
24
Protein-energy malnutrition: its effects on 4 metabolic parameters]. (7612711)
1995
25
Protein energy malnutrition in severe alcoholic hepatitis: diagnosis and response to treatment. The VA Cooperative Study Group #275. (8523623)
1995
26
Long-chain polyunsaturated fatty acids in children with severe protein-energy malnutrition with and without human immunodeficiency virus-1 infection. (7491893)
1995
27
Computerized cry analysis in infants affected by severe protein energy malnutrition. (8193504)
1994
28
Protein-energy malnutrition in cystic fibrosis patients. (8025359)
1994
29
Diabetes in pregnancy: fetal macrosomia, hyperinsulinism, and islet hyperplasia in the offspring of rats subjected to temporary protein-energy malnutrition early in life. (8108195)
1993
30
The worldwide magnitude of protein-energy malnutrition: an overview from the WHO Global Database on Child Growth. (8313488)
1993
31
Ultrastructure of the islets of Langerhans in protein-energy malnutrition. (8273316)
1993
32
Sex-hormone-binding globulin and protein-energy malnutrition indexes as indicators of nutritional status in women with anorexia nervosa. (8438764)
1993
33
Skeletal muscle wasting and protein-energy malnutrition in children with a newly diagnosed acute leukemia. (2114940)
1990
34
Vitamin E status in Sudanese children with protein-energy malnutrition. (2110395)
1990
35
Value of serum transthyretin measurements in the assessment of marginal protein-energy malnutrition in rats. (2457071)
1988
36
Arm circumference as an index of protein-energy malnutrition in six- to eleven-month old rural Tanzanian children. (3146648)
1988
37
Hair root morphology as an index of protein energy malnutrition. (3149675)
1988
38
Protein-energy malnutrition increases teratogenicity of hypervitaminosis A in rats. (3147800)
1988
39
Gestational protein-energy malnutrition affects the composition of developing skins of rat fetuses and their dams. (3118938)
1987
40
Classification of protein-energy malnutrition in industrialized countries. (3090869)
1986
41
Protein-energy malnutrition and risk of infection. (3099300)
1986
42
Small bowel function in mild to moderate protein-energy malnutrition. (3100443)
1986
43
Effect of protein-energy malnutrition on drug metabolism in man. (6433561)
1984
44
Plasma lipids and lipoprotein cholesterol in undernourished diabetic subjects and adults with protein energy malnutrition. (6439533)
1984
45
Folate levels and deoxyuridine suppression tests in protein-energy malnutrition. (6401209)
1983
46
Serum phosphorus in protein energy malnutrition. (6821115)
1982
47
Plasma alpha-tocopherol (vitamin E) levels and tocopherol-lipid ratio among children with protein-energy malnutrition (PEM). (6185084)
1982
48
High-density-lipoprotein-cholesterol in protein-energy malnutrition. (6805501)
1982
49
Transcobalamin II in protein-energy malnutrition among residents of the Kivu area. (7139939)
1982
50
Outcome of children with severe grades of protein energy malnutrition in an I.C.D.S. block. (6797942)
1981

Variations for Protein-Energy Malnutrition

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Expression for genes affiliated with Protein-Energy Malnutrition

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Expression patterns in normal tissues for genes affiliated with Protein-Energy Malnutrition

Search GEO for disease gene expression data for Protein-Energy Malnutrition.

Pathways for genes affiliated with Protein-Energy Malnutrition

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Compounds for genes affiliated with Protein-Energy Malnutrition

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Compounds related to Protein-Energy Malnutrition according to GeneCards/GeneDecks:

(show all 37)
idCompoundScoreTop Affiliating Genes
1styrene449.8RBP4, EPHX1
2purpurin449.8RBP4, TTR
3retinyl palmitate44 2410.7TTR, RBP4
4lutein449.7RBP4, TTR
5tocopherol449.7TTR, RBP4
6cellulose acetate449.7RBP4, TTR
7mspi449.7EPHX1, TTR
8phosphorus449.7RBP4, TTR
9isoleucine449.7RBP4, TTR
10betacarotene449.7RBP4, TTR
11triiodothyronine449.7RBP4, TTR
12uric acid44 2410.6RBP4, TTR
13vitamin-e449.6TTR, RBP4
14alpha tocopherol449.6TTR, RBP4
15resveratrol44 61 24 1112.6TTR, EPHX1
16urea44 24 1111.5RBP4, TTR
17amide449.5CCK, EPHX1
18thyroxine44 2410.4RBP4, TTR
19sulfate44 2410.4EPHX1, CCK
20valine449.3RBP4, TTR
21vitamin a44 24 1111.3PIGR, TTR, RBP4
22leucine449.2PIGR, TTR, RBP4
23carbohydrates449.2CCK, TTR
24alanine449.1RBP4, TTR, PIGR
25pyruvate449.1TTR, PIGR
26aspirin44 50 28 2412.0CCK, TTR
27estrogen449.0TTR, EPHX1, RBP4
28glycerol44 24 1110.9TTR, CCK
29folate448.9TTR, CCK, RBP4
30dopamine44 28 24 1111.9TTR, CCK, RBP4
31adenylate448.9RBP4, CCK, TTR
32testosterone44 61 24 1111.8TTR, CCK, RBP4
33dexamethasone44 50 28 1111.8TTR, CCK, RBP4
34arginine448.8CCK, EPHX1, TTR
35glucose448.6TTR, CCK, RBP4
36retinoic acid44 249.5RBP4, CCK, TTR, PIGR
37cholesterol44 28 24 1111.4RBP4, CCK, EPHX1, TTR

GO Terms for genes affiliated with Protein-Energy Malnutrition

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Cellular components related to Protein-Energy Malnutrition according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056158.1RBP4, CCK, TTR, PIGR

Biological processes related to Protein-Energy Malnutrition according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1phototransduction, visible lightGO:0076039.3RBP4, TTR
2retinol metabolic processGO:0425729.2RBP4, TTR
3retinoid metabolic processGO:0015239.0RBP4, TTR

Molecular functions related to Protein-Energy Malnutrition according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:0051799.0CCK, TTR

Products for genes affiliated with Protein-Energy Malnutrition

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Sources for Protein-Energy Malnutrition

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet