MCID: PRT038
MIFTS: 40

Protein-Energy Malnutrition malady

Metabolic diseases category

Aliases & Classifications for Protein-Energy Malnutrition

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Protein-Energy Malnutrition, Aliases & Descriptions:

Name: Protein-Energy Malnutrition 9 11 43 60
 
Pem 37


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Metabolic diseases


External Ids:

Disease Ontology9 DOID:11801
MeSH33 D011502
NCIt38 C34952
ICD9CM27 263.9
ICD1025 E46

Summaries for Protein-Energy Malnutrition

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Wikipedia:63 Protein?energy malnutrition (PEM) or protein?calorie malnutrition refers to a form of malnutrition where... more...

MalaCards based summary: Protein-Energy Malnutrition, also known as pem, is related to liver cirrhosis and hepatitis. An important gene associated with Protein-Energy Malnutrition is PIGR (polymeric immunoglobulin receptor), and among its related pathways are Diseases associated with visual transduction and Visual Cycle in Retinal Rods. The compounds styrene and purpurin have been mentioned in the context of this disorder. Affiliated tissues include bone, liver and brain, and related mouse phenotype homeostasis/metabolism.

Related Diseases for Protein-Energy Malnutrition

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Graphical network of the top 20 diseases related to Protein-Energy Malnutrition:



Diseases related to protein-energy malnutrition

Symptoms for Protein-Energy Malnutrition

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Drugs & Therapeutics for Protein-Energy Malnutrition

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Drug clinical trials:

Search ClinicalTrials for Protein-Energy Malnutrition

Search NIH Clinical Center for Protein-Energy Malnutrition

Genetic Tests for Protein-Energy Malnutrition

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Anatomical Context for Protein-Energy Malnutrition

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MalaCards organs/tissues related to Protein-Energy Malnutrition:

31
Bone, Liver, Brain, Testes, Thyroid, Bone marrow, Thymus, Small intestine, Heart, Skeletal muscle, Kidney, Skin, T cells, B cells, Colon, Pancreas, Placenta, Monocytes, Pituitary, Neutrophil

Animal Models for Protein-Energy Malnutrition or affiliated genes

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MGI Mouse Phenotypes related to Protein-Energy Malnutrition:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053767.5RBP4, CCK, EPHX1, TTR, PIGR

Publications for Protein-Energy Malnutrition

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Articles related to Protein-Energy Malnutrition:

(show top 50)    (show all 509)
idTitleAuthorsYear
1
Cystic fibrosis: from protein-energy malnutrition to obesity with dyslipidemia. (24800027)
2013
2
A narrative review of recent progress in understanding the relationship between tuberculosis and protein energy malnutrition. (23942176)
2013
3
Protein-energy malnutrition alters IgA responses to rotavirus vaccination and infection but does not impair vaccine efficacy in mice. (24200975)
2013
4
Hepatoprotective and nephroprotective effects of Cnidoscolus aconitifolius in protein energy malnutrition induced liver and kidney damage. (24174819)
2013
5
Evaluating risk factors for protein-energy malnutrition in children under the age of six years: a case-control study from Iran. (21887115)
2011
6
Protein-energy malnutrition alters hippocampal plasticity-associated protein expression following global ischemia in the gerbil. (20883206)
2010
7
Study of lymphocyte subpopulations in bone marrow in a model of protein-energy malnutrition. (20036516)
2010
8
Serum ghrelin in infants with protein-energy malnutrition. (19261361)
2009
9
Serum ghrelin levels in children with primary protein-energy malnutrition. (18937750)
2008
10
Current prevalence and predictors of protein-energy malnutrition among schoolchildren in rural Peninsular Malaysia. (19058591)
2008
11
Effect of protein-energy malnutrition on erythropoietin requirement in maintenance hemodialysis patients. (17403171)
2007
12
Protein-energy malnutrition alters histological and ultrastructural characteristics of the bone marrow and decreases haematopoiesis in adult mice. (17357095)
2007
13
Pancreatic size in protein energy malnutrition: a predictor of nutritional recovery. (15536474)
2005
14
Detection of severe protein-energy malnutrition by nurses in The Gambia. (14736639)
2004
15
An evaluation of re-orientation training program of ICDS functionaries on protein-energy malnutrition. (11439866)
2000
16
Micronutrient deficiencies and protein-energy malnutrition. (9635975)
1998
17
Effects of protein-energy malnutrition on muscarinic receptor density and acetylcholinesterase activity in rat brain. (9195001)
1997
18
Vitamin E status in protein energy malnutrition. (23100878)
1997
19
Correction of protein-energy malnutrition in older adults: effects of a short-term aerobic training program. (16844611)
1997
20
Profile of protein energy malnutrition amongst children under four years in urban areas of Rivers State. (8652441)
1996
21
The clinical assessment of adult patients with protein energy malnutrition. (7659057)
1995
22
The computed axial tomography of the brain in protein energy malnutrition. (8687211)
1995
23
Protein-energy malnutrition: its effects on 4 metabolic parameters]. (7612711)
1995
24
Protein energy malnutrition in severe alcoholic hepatitis: diagnosis and response to treatment. The VA Cooperative Study Group #275. (8523623)
1995
25
Long-chain polyunsaturated fatty acids in children with severe protein-energy malnutrition with and without human immunodeficiency virus-1 infection. (7491893)
1995
26
Computerized cry analysis in infants affected by severe protein energy malnutrition. (8193504)
1994
27
Protein-energy malnutrition in cystic fibrosis patients. (8025359)
1994
28
Diabetes in pregnancy: fetal macrosomia, hyperinsulinism, and islet hyperplasia in the offspring of rats subjected to temporary protein-energy malnutrition early in life. (8108195)
1993
29
The worldwide magnitude of protein-energy malnutrition: an overview from the WHO Global Database on Child Growth. (8313488)
1993
30
Ultrastructure of the islets of Langerhans in protein-energy malnutrition. (8273316)
1993
31
Sex-hormone-binding globulin and protein-energy malnutrition indexes as indicators of nutritional status in women with anorexia nervosa. (8438764)
1993
32
Skeletal muscle wasting and protein-energy malnutrition in children with a newly diagnosed acute leukemia. (2114940)
1990
33
Vitamin E status in Sudanese children with protein-energy malnutrition. (2110395)
1990
34
Value of serum transthyretin measurements in the assessment of marginal protein-energy malnutrition in rats. (2457071)
1988
35
Arm circumference as an index of protein-energy malnutrition in six- to eleven-month old rural Tanzanian children. (3146648)
1988
36
Hair root morphology as an index of protein energy malnutrition. (3149675)
1988
37
Protein-energy malnutrition increases teratogenicity of hypervitaminosis A in rats. (3147800)
1988
38
Gestational protein-energy malnutrition affects the composition of developing skins of rat fetuses and their dams. (3118938)
1987
39
Classification of protein-energy malnutrition in industrialized countries. (3090869)
1986
40
Protein-energy malnutrition and risk of infection. (3099300)
1986
41
Small bowel function in mild to moderate protein-energy malnutrition. (3100443)
1986
42
Effect of protein-energy malnutrition on drug metabolism in man. (6433561)
1984
43
Plasma lipids and lipoprotein cholesterol in undernourished diabetic subjects and adults with protein energy malnutrition. (6439533)
1984
44
Protein-energy malnutrition in Nigerian children in Savanna belt. (6429350)
1984
45
Folate levels and deoxyuridine suppression tests in protein-energy malnutrition. (6401209)
1983
46
Serum phosphorus in protein energy malnutrition. (6821115)
1982
47
Plasma alpha-tocopherol (vitamin E) levels and tocopherol-lipid ratio among children with protein-energy malnutrition (PEM). (6185084)
1982
48
High-density-lipoprotein-cholesterol in protein-energy malnutrition. (6805501)
1982
49
Transcobalamin II in protein-energy malnutrition among residents of the Kivu area. (7139939)
1982
50
Outcome of children with severe grades of protein energy malnutrition in an I.C.D.S. block. (6797942)
1981

Variations for Protein-Energy Malnutrition

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Expression for genes affiliated with Protein-Energy Malnutrition

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Search GEO for disease gene expression data for Protein-Energy Malnutrition.

Pathways for genes affiliated with Protein-Energy Malnutrition

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Pathways related to Protein-Energy Malnutrition according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.3RBP4, TTR
29.3RBP4, TTR
3
Show member pathways
9.3RBP4, TTR

Compounds for genes affiliated with Protein-Energy Malnutrition

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Compounds related to Protein-Energy Malnutrition according to GeneCards Suite gene sharing:

(show all 37)
idCompoundScoreTop Affiliating Genes
1styrene439.8RBP4, EPHX1
2purpurin439.8RBP4, TTR
3retinyl palmitate43 2410.7TTR, RBP4
4lutein439.7RBP4, TTR
5tocopherol439.7TTR, RBP4
6cellulose acetate439.7RBP4, TTR
7mspi439.7EPHX1, TTR
8phosphorus439.7RBP4, TTR
9isoleucine439.7RBP4, TTR
10betacarotene439.7RBP4, TTR
11triiodothyronine439.7RBP4, TTR
12uric acid43 2410.6RBP4, TTR
13vitamin-e439.6TTR, RBP4
14alpha tocopherol439.6TTR, RBP4
15resveratrol43 59 24 1212.6TTR, EPHX1
16urea43 24 1211.5RBP4, TTR
17amide439.5CCK, EPHX1
18thyroxine43 2410.4RBP4, TTR
19sulfate43 2410.4EPHX1, CCK
20valine439.3RBP4, TTR
21vitamin a43 24 1211.3PIGR, TTR, RBP4
22leucine439.2PIGR, TTR, RBP4
23carbohydrates439.2CCK, TTR
24alanine439.1RBP4, TTR, PIGR
25pyruvate439.1TTR, PIGR
26aspirin43 49 28 2412.0CCK, TTR
27estrogen439.0TTR, EPHX1, RBP4
28glycerol43 24 1210.9TTR, CCK
29folate438.9TTR, CCK, RBP4
30dopamine43 28 24 1211.9TTR, CCK, RBP4
31adenylate438.9RBP4, CCK, TTR
32testosterone43 59 24 1211.8TTR, CCK, RBP4
33dexamethasone43 49 28 1211.8TTR, CCK, RBP4
34arginine438.8CCK, EPHX1, TTR
35glucose438.6TTR, CCK, RBP4
36retinoic acid43 249.5RBP4, CCK, TTR, PIGR
37cholesterol43 28 24 1211.4RBP4, CCK, EPHX1, TTR

GO Terms for genes affiliated with Protein-Energy Malnutrition

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Cellular components related to Protein-Energy Malnutrition according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056158.1RBP4, CCK, TTR, PIGR

Biological processes related to Protein-Energy Malnutrition according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1phototransduction, visible lightGO:00076039.3RBP4, TTR
2retinol metabolic processGO:00425729.2RBP4, TTR
3retinoid metabolic processGO:00015239.0RBP4, TTR

Molecular functions related to Protein-Energy Malnutrition according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:00051799.0CCK, TTR

Products for genes affiliated with Protein-Energy Malnutrition

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Protein-Energy Malnutrition

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet