PEM
MCID: PRT038
MIFTS: 49

Protein-Energy Malnutrition (PEM) malady

Categories: Metabolic diseases

Aliases & Classifications for Protein-Energy Malnutrition

Aliases & Descriptions for Protein-Energy Malnutrition:

Name: Protein-Energy Malnutrition 12 52 42 14 69
Pem 45

Classifications:



External Ids:

Disease Ontology 12 DOID:11801
ICD10 33 E46
ICD9CM 35 263.9
MeSH 42 D011502
NCIt 47 C34952
UMLS 69 C0033677

Summaries for Protein-Energy Malnutrition

MalaCards based summary : Protein-Energy Malnutrition, also known as pem, is related to alcoholic hepatitis and meningitis, and has symptoms including cachexia and emaciation. An important gene associated with Protein-Energy Malnutrition is ALB (Albumin), and among its related pathways/superpathways are Dilated cardiomyopathy and Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. The drugs Morphine and Acetaminophen have been mentioned in the context of this disorder. Affiliated tissues include bone, liver and testes, and related phenotypes are hematopoietic system and homeostasis/metabolism

Wikipedia : 71 Protein–energy malnutrition (PEM) or protein–calorie malnutrition refers to a form of malnutrition... more...

Related Diseases for Protein-Energy Malnutrition

Diseases related to Protein-Energy Malnutrition via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 204)
id Related Disease Score Top Affiliating Genes
1 alcoholic hepatitis 29.5 IL6 TF TNF
2 meningitis 29.3 IL6 LEP TNF
3 phaeochromocytoma 10.3 ALB TTR
4 atopic dermatitis 6 10.3 ALB CD79A
5 ehlers-danlos syndrome, periodontal type 1 10.3 ALB TTR
6 colloid adenoma 10.3 ALB CD79A
7 schneiderian carcinoma 10.3 ALB CD79A
8 neurological manifestations of pompe disease 10.3 ALB CP
9 acute female pelvic peritonitis 10.3 CD79A TTR
10 loeffler syndrome 10.3 CD79A CP
11 striatonigral degeneration 10.2 ALB CD79A
12 congenital dyserythropoietic anemia 10.2 ALB TNF
13 infertility due to extratesticular cause 10.2 ALB CD79A
14 congenital nystagmus 10.2 ALB CD79A
15 focal epithelial hyperplasia 10.2 ALB TF TTR
16 coronary artery dissection, spontaneous 10.2 ALB CD79A TF
17 malignant hyperthermia susceptibility 1 10.2 ALB CD79A TF
18 choriodal dystrophy, central areolar 2 10.2 TF TTR
19 thyroiditis 10.2
20 uterine ligament serous adenocarcinoma 10.2 ALB CD79A TTR
21 cellulitis 10.2 CD79A TTR
22 kwashiorkor 10.2
23 cataract 10.1 ALB TNF TTR
24 bile duct mucoepidermoid carcinoma 10.1 ALB LEP TF
25 hemangioma of orbit 10.1 CD79A TNF
26 malaria 10.1
27 hepatitis 10.1
28 dermatomycosis 10.1 ALB CD79A TNF
29 choreatic disease 10.1 ALB CD79A TNF
30 hematocele of tunica vaginalis testis 10.1 CP TNF TTR
31 anogenital venereal wart 10.1 ALB TNF TTR
32 familial renal papillary carcinoma 10.1 ALB CD79A TNF
33 uterus interstitial leiomyoma 10.1 ALB CD79A TNF
34 male genital organ stricture 10.1 ALB CD79A TF TTR
35 spastic entropion 10.1 ALB CD79A TF TTR
36 biliary cirrhosis, primary, 2 10.1 ALB CD79A TNF
37 liver cirrhosis 10.1
38 ischemia 10.1
39 shoulder impingement syndrome 10.1 ALB IL6
40 rosacea 10.1 ALB CP GPT
41 isolated growth hormone deficiency 10.1 ALB CP GPT
42 congenital intrinsic factor deficiency 10.1 CD79A GPT TF
43 brain stem glioma 10.1 ALB IGF1 LEP
44 episcleritis periodica fugax 10.0 CP GPT TF
45 tracheal calcification 10.0 GPT TNF
46 pancreatitis 10.0
47 marasmus 10.0
48 peritonitis 10.0
49 generalized atherosclerosis 10.0 CD79A IL6
50 inner ear disease 10.0 ALB IL6 TTR

Comorbidity relations with Protein-Energy Malnutrition via Phenotypic Disease Network (PDN): (show top 50) (show all 152)


Acquired Thrombocytopenia Active Peptic Ulcer Disease
Acute Conjunctivitis Acute Cystitis
Acute Kidney Failure Acute Myocardial Infarction
Acute Pancreatitis Adrenal Cortical Hypofunction
Alcohol Abuse Alcoholic Hepatitis
Alcoholic Liver Cirrhosis Alcoholic Neuropathy
Alzheimer Disease Amyotrophic Lateral Sclerosis 1
Anorexia Nervosa Anxiety Disorder
Aplastic Anemia Atrophic Gastritis
Bacteremia Biliary Tract Neoplasm
Bronchiectasis Bronchitis
Bronchopneumonia Bullous Pemphigoid
Candidiasis Cardiac Arrest
Cecal Benign Neoplasm Celiac Disease
Cerebral Atherosclerosis Cerebral Degeneration
Cerebrovascular Disease Cholangitis
Cholecystitis Cholestasis
Chronic Kidney Failure Chronic Myocardial Ischemia
Chronic Pulmonary Heart Disease Chronic Ulcer of Skin
Chylomicron Retention Disease Colorectal Cancer
Conjunctivitis Crohn's Disease
Cystitis Decubitus Ulcer
Deficiency Anemia Dental Caries
Dermatomycosis Disseminated Intravascular Coagulation
Duodenum Cancer Dyskinesia of Esophagus

Graphical network of the top 20 diseases related to Protein-Energy Malnutrition:



Diseases related to Protein-Energy Malnutrition

Symptoms & Phenotypes for Protein-Energy Malnutrition

UMLS symptoms related to Protein-Energy Malnutrition:


cachexia, emaciation

MGI Mouse Phenotypes related to Protein-Energy Malnutrition:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.91 CD79A CP GPT IGF1 IL6 LEP
2 homeostasis/metabolism MP:0005376 9.85 ALB CD79A CP IGF1 IL6 LEP
3 liver/biliary system MP:0005370 9.43 ALB CD79A CP IL6 LEP TNF
4 neoplasm MP:0002006 9.1 ALB CD79A IGF1 IL6 LEP TNF

Drugs & Therapeutics for Protein-Energy Malnutrition

Drugs for Protein-Energy Malnutrition (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 153)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Morphine Approved, Investigational Phase 4,Phase 3 57-27-2 5288826
2
Acetaminophen Approved Phase 4,Phase 3,Phase 2 103-90-2 1983
3
Naproxen Approved, Vet_approved Phase 4 22204-53-1 1302 156391
4
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
5
Buprenorphine Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 3 52485-79-7 40400 644073
6
chenodeoxycholic acid Approved Phase 4 474-25-9 10133
7
Naltrexone Approved, Investigational, Vet_approved Phase 4 16590-41-3 5360515
8 Analgesics Phase 4,Phase 3,Phase 2
9 Analgesics, Opioid Phase 4,Phase 3,Phase 2
10 Antirheumatic Agents Phase 4,Phase 3,Phase 2
11 Central Nervous System Depressants Phase 4,Phase 3,Phase 2
12 Narcotics Phase 4,Phase 3,Phase 2
13 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
14 Antimetabolites Phase 4,Phase 2
15 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2
16 Anti-Inflammatory Agents Phase 4,Phase 3
17 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 3
18 Cyclooxygenase Inhibitors Phase 4
19 Narcotic Antagonists Phase 4,Phase 3
20 Liver Extracts Phase 4
21 Cystatins Phase 4
22 HIV Protease Inhibitors Phase 4
23
protease inhibitors Phase 4
24 Anticholesteremic Agents Phase 4
25 Bile Acids and Salts Phase 4
26 Cathartics Phase 4
27 Colesevelam Hydrochloride Phase 4
28 Gastrointestinal Agents Phase 4
29 Glucagon-Like Peptide 1 Phase 4
30 Hypolipidemic Agents Phase 4
31 Laxatives Phase 4
32 Lipid Regulating Agents Phase 4
33 cysteine Nutraceutical Phase 4,Phase 1
34 isoleucine Nutraceutical Phase 4
35 leucine Nutraceutical Phase 4
36 valine Nutraceutical Phase 4
37
Pentoxifylline Approved, Investigational Phase 3 6493-05-6 4740
38
Chlorhexidine Approved, Vet_approved Phase 3 55-56-1 9552079 2713
39
Lubiprostone Approved, Investigational Phase 3 136790-76-6 656719
40
Sodium oxybate Approved Phase 3 502-85-2 5360545
41
Hydrocodone Approved, Illicit Phase 3 125-29-1 5284569
42
Methyltestosterone Approved Phase 3 58-18-4 6010
43
Testosterone Approved, Investigational Phase 3 58-22-0 6013
44 Antioxidants Phase 3,Phase 1
45 Anti-Infective Agents Phase 3,Phase 2
46 Dermatologic Agents Phase 3,Phase 2
47 Chelating Agents Phase 3
48 Phosphodiesterase Inhibitors Phase 3
49 Platelet Aggregation Inhibitors Phase 3
50 Protective Agents Phase 3

Interventional clinical trials:

(show top 50) (show all 89)
id Name Status NCT ID Phase
1 Egg Albumin-Based Protein Supplement Versus Renal-specific Supplement in Hemodialysis Patients Unknown status NCT01981083 Phase 4
2 Controlled-Release Oxycodone Versus Naproxen at Home After Ambulatory Surgery: A Randomized Controlled Trial Completed NCT02152592 Phase 4
3 Integration of Buprenorphine Into HIV Clinical Settings - Primary Care Model (PCM) Completed NCT00798538 Phase 4
4 Malnutrition in Gastroenterology Patients Completed NCT00168935 Phase 4
5 Nutritional Intervention in Malnourished Elderly Patients Completed NCT00417508 Phase 4
6 Enteral Nutrition in Liver Cirrhosis Completed NCT00168961 Phase 4
7 Kidney Response to Sepsis Affects Angiogenic Balance and Likelihood of CCI and PICS Recruiting NCT02276066 Phase 4
8 Effects of Bile Acids and Bile Acid Sequestrants on GLP-1 Secretion After Roux-en-Y Gastric Bypass Recruiting NCT02876484 Phase 4
9 Branched-chain Amino Acid (BCAA) on Progression of Advanced Liver Disease Active, not recruiting NCT02837302 Phase 4
10 Conversion to Embeda With Rescue Trial Terminated NCT01179191 Phase 4
11 Use of Morphine Gel Topically in Patients With Stage 2-3 Wounds Unknown status NCT00755989 Phase 3
12 Post-Approval Clinical Trial of the PCM® Cervical Disc Completed NCT01905930 Phase 3
13 PCM Cervical Disc System Completed NCT00578812 Phase 3
14 Efficacy,Safety and Quality of Life After TOOKAD® Soluble VTP for Localized Prostate Cancer Completed NCT01875393 Phase 3
15 Efficacy and Safety Study of TOOKAD® Soluble for Localised Prostate Cancer Compared to Active Surveillance. Completed NCT01310894 Phase 3
16 Anit-Inflammatory and Anti-Oxidative Nutrition in Dialysis Patients Completed NCT00561093 Phase 3
17 Newborn Kit to Save Lives and Brains in Kenya Completed NCT02208960 Phase 3
18 Opioid-induced Bowel Dysfunction Pivotal Assessment of Lubiprostone Completed NCT00597428 Phase 3
19 Safety and Efficacy Study of Xyrem® (Sodium Oxybate) in Subjects With Fibromyalgia. Completed NCT00423605 Phase 3
20 A Safety and Efficacy Study of Xyrem® in Subjects With Fibromyalgia Completed NCT00371137 Phase 3
21 Safety and Efficacy of Dose Conversion From Vicodin® to Buprenorphine Transdermal System (Butrans™) in Subjects With OA Pain Completed NCT00312572 Phase 3
22 Multimodal Therapeutic Approach in Undernourished Maintenance Hemodialysis Patients (AMERICANO) Recruiting NCT02418065 Phase 3
23 Protein-energy Oral Supplementation Enriched With Omega-3 Fatty Acids in Cardiac Cachexia Terminated NCT00748332 Phase 3
24 Whole Body Cooling Using Phase Changing Material Unknown status NCT01138176 Phase 1, Phase 2
25 Cyclophosphamide Versus Methotrexate for Remission Maintenance in Systemic Necrotizing Vasculitides Unknown status NCT00751517 Phase 2
26 Study of Efficacy of Induction Chemotherapy With Gemcitabine and Carboplatin for Operable Non-small-cell Lung Cancer Before Surgery Unknown status NCT00563160 Phase 2
27 Violence and Stress Assessment (ViStA) Project to Improve Post Traumatic Stress Disorder Management in Primary Care Completed NCT01401101 Phase 2
28 Study Using WST11 in Patients With Localized Prostate Cancer Completed NCT00975429 Phase 2
29 Safety and Tolerability Study Using WST11 In Patients With Localized Prostate Cancer Completed NCT00946881 Phase 1, Phase 2
30 Study of WST11 in Patients With Localized Prostate Cancer Completed NCT00707356 Phase 2
31 Collection of Transplant Stem Cells for Plasma Cell Myeloma Active, not recruiting NCT01547806 Phase 2
32 NutFish and Nutrient Supplementation in Pregnancy Class to Improve Maternal and Birth Outcomes Not yet recruiting NCT02959125 Phase 2
33 Paracetamol for Intrapartum Analgesia Not yet recruiting NCT02578251 Phase 2
34 Clinical Performance of the Embrace Isothermal Mattress Unknown status NCT01425086 Phase 1
35 Study of Antioxidants and Oxidants in Malnourished Children Unknown status NCT00069134 Phase 1
36 Acceptability and Efficacy of 'Fish Surimi Peptide' in Under Five Children Suffering From Moderate Acute Malnutrition Recruiting NCT02272543 Phase 1
37 Phase 1 Study of LOXO-292 in Patients With Advanced Solid Tumors, RET-Fusion Lung Cancer and Medullary Thyroid Cancer Recruiting NCT03157128 Phase 1
38 A Phase I Trial Evaluating mFOLFOX6 and Avastin With Nexavar as First-Line Treatment for Metastatic Colorectal Cancer Terminated NCT00779311 Phase 1
39 The Impact of Perioperational Malnutrition on the Cost on Gastroenterological Cancer Patients Unknown status NCT00987883
40 Malnutrition, Diet and Racial Disparities in Chronic Kidney Disease (CKD) Unknown status NCT01415570
41 Evaluation of the Effectiveness of a Protein Pulse-Feeding Pattern in Elderly Patients Completed NCT00135590
42 Energy Dense Formula to People Living in Old Peoples Home Completed NCT01259999
43 Enhancing HIV Prevention by Using Behavioral Intervention Among HIV-Infected Men Completed NCT00231972
44 aCGH Impacts Survival in Plasma Cell PTLD Completed NCT02984215
45 Bioelectrical Impedance Vector Analysis in Cirrhotic Patients Completed NCT01603953
46 Visibility of Lesion Characteristics With Phase Contrast Mammography Completed NCT00467727
47 Two Techniques for Root Coverage With a Xenogeneic Collagen Matrix Completed NCT02129504
48 MostCare Versus Echo-Doppler for Cardiac Output Measurement Completed NCT01678950
49 Adding Malabsorption for Failed Gastric Bypass Completed NCT01040481
50 A Nutrition/Hygiene Education Program for the Prevention of Child Malnutrition in Rural Kenya Completed NCT01679535

Search NIH Clinical Center for Protein-Energy Malnutrition

Cochrane evidence based reviews: protein-energy malnutrition

Genetic Tests for Protein-Energy Malnutrition

Anatomical Context for Protein-Energy Malnutrition

MalaCards organs/tissues related to Protein-Energy Malnutrition:

39
Bone, Liver, Testes, Brain, Thyroid, Bone Marrow, Skeletal Muscle

Publications for Protein-Energy Malnutrition

Articles related to Protein-Energy Malnutrition:

(show top 50) (show all 529)
id Title Authors Year
1
Protein-energy malnutrition in the rehabilitation setting: Evidence to improve identification. ( 26921933 )
2016
2
Does protein energy malnutrition affect the outcome in Tunisian cirrhotic patients? ( 27532543 )
2016
3
Protein energy malnutrition associates with different types of hearing impairments in toddlers: Anemia increases cochlear dysfunction. ( 27240492 )
2016
4
Serum hyaluronic acid predicts protein-energy malnutrition in chronic hepatitis C. ( 27311000 )
2016
5
Prognostic significance of low skeletal muscle mass compared with protein-energy malnutrition in liver cirrhosis. ( 27862791 )
2016
6
The Arid Melancholy-Netherton Syndrome With Protein Energy Malnutrition. ( 27190931 )
2016
7
Factors Associated With Protein-energy Malnutrition in Chronic Liver Disease: Analysis Using Indirect Calorimetry. ( 26765430 )
2016
8
Protein-energy malnutrition is frequent and precocious in children with cri du chat syndrome. ( 26872355 )
2016
9
Convergence of a diabetes mellitus, protein energy malnutrition, and TB epidemic: the neglected elderly population. ( 27456231 )
2016
10
Protein Energy Malnutrition during Vaccination Has Limited Influence on Vaccine Efficacy but Abolishes Immunity if Administered during Mycobacterium tuberculosis Infection. ( 25754202 )
2015
11
Serum vitamin D status in children with protein-energy malnutrition admitted to a national referral hospital in Uganda. ( 26346815 )
2015
12
Leucine Supplementation Improves Acquired Growth Hormone Resistance in Rats with Protein-Energy Malnutrition. ( 25909895 )
2015
13
Protein-Energy Malnutrition Causes Deficits in Motor Function in Adult Male Rats. ( 26423735 )
2015
14
Protein-energy malnutrition: a risk factor for various ailments. ( 24915388 )
2015
15
Evaluation of dental age in protein energy malnutrition children. ( 26538919 )
2015
16
Seroprevalence rate of Poliovirus antibodies among the Healthy and Protein Energy Malnutrition children. ( 26101500 )
2015
17
Protein-energy malnutrition at mid-adulthood does not imprint long-term metabolic consequences in male rats. ( 26133298 )
2015
18
Prevalence of protein-energy malnutrition in hospital patients over 75 years of age admitted for hip fracture. ( 24998085 )
2014
19
Protein energy malnutrition in India: the plight of our under five children. ( 24791240 )
2014
20
Determinants of protein-energy malnutrition in community dwelling older adults: A systematic review of observational studies. ( 25257179 )
2014
21
Protein-energy Malnutrition in Goitrous Schoolchildren of Isfahan, Iran. ( 24932384 )
2014
22
Protein-energy malnutrition developing after global brain ischemia induces an atypical acute-phase response and hinders expression of GAP-43. ( 25259609 )
2014
23
Free radicals and antioxidant status in protein energy malnutrition. ( 24790610 )
2014
24
Protein Energy-Malnutrition: Does the In Vitro Zinc Sulfate Supplementation Improve Chromosomal Damage Repair? ( 25262017 )
2014
25
Maternal protein-energy malnutrition during early pregnancy in sheep impacts the fetal ornithine cycle to reduce fetal kidney microvascular development. ( 25077559 )
2014
26
Protein energy malnutrition increases arginase activity in monocytes and macrophages. ( 25392710 )
2014
27
Effect of a probiotic fermented milk on the thymus in Balb/c mice under non-severe protein-energy malnutrition. ( 23286742 )
2013
28
Effect of early childhood protein-energy malnutrition on permanent dentition dental caries. ( 24255941 )
2013
29
Cystic fibrosis: from protein-energy malnutrition to obesity with dyslipidemia. ( 24800027 )
2013
30
A comparison of the full Mini Nutritional Assessment, short-form Mini Nutritional Assessment, and Subjective Global Assessment to predict the risk of protein-energy malnutrition in patients on peritoneal dialysis: a cross-sectional study. ( 23000089 )
2013
31
Protein-energy malnutrition induces an aberrant acute-phase response and modifies the circadian rhythm of core temperature. ( 23855272 )
2013
32
Protein energy malnutrition decreases immunity and increases susceptibility to influenza infection in mice. ( 22949306 )
2013
33
Relation of oxidative stress, zinc and alkaline phosphatase in protein energy malnutrition. ( 23373727 )
2013
34
Protein-energy malnutrition alters IgA responses to rotavirus vaccination and infection but does not impair vaccine efficacy in mice. ( 24200975 )
2013
35
Methicillin-resistant Staphylococcus aureus carriage in infants with protein-energy malnutrition. ( 24502042 )
2013
36
Acquired protein energy malnutrition in glutaric acidemia. ( 23330977 )
2013
37
Missed opportunities in the diagnosis and management of protein energy malnutrition among children under 5 years in Wakiso district, Uganda. ( 25035810 )
2013
38
Rutin (quercetin rutinoside) induced protein-energy malnutrition in chronic kidney disease, but quercetin acted beneficially. ( 23876017 )
2013
39
Hepatoprotective and nephroprotective effects of Cnidoscolus aconitifolius in protein energy malnutrition induced liver and kidney damage. ( 24174819 )
2013
40
Hematologic and Bone Marrow Changes in Children with Protein-Energy Malnutrition. ( 23987917 )
2013
41
Porcine placenta mitigates protein-energy malnutrition-induced fatigue. ( 24035056 )
2013
42
A narrative review of recent progress in understanding the relationship between tuberculosis and protein energy malnutrition. ( 23942176 )
2013
43
Protein-energy malnutrition during early gestation in sheep blunts fetal renal vascular and nephron development and compromises adult renal function. ( 22106177 )
2012
44
Effect of honey supplementation on the phagocytic function during nutritional rehabilitation of protein energy malnutrition patients. ( 21628388 )
2012
45
Protein energy malnutrition impairs homeostatic proliferation of memory CD8 T cells. ( 22116826 )
2012
46
Language skills and intelligence quotient of protein energy malnutrition survivors. ( 21930668 )
2012
47
The effect of serum magnesium levels and serum endothelin-1 levels on bone mineral density in protein energy malnutrition. ( 23155975 )
2012
48
Protein-energy malnutrition in hospitalized patients: early assessment for better outcome. ( 22953619 )
2012
49
Under-five protein energy malnutrition admitted at the University of Nigeria Teaching Hospital, Enugu: a 10 year retrospective review. ( 22704641 )
2012
50
Practical dietary management of protein energy malnutrition in young children with cow's milk protein allergy. ( 22435534 )
2012

Variations for Protein-Energy Malnutrition

Expression for Protein-Energy Malnutrition

Search GEO for disease gene expression data for Protein-Energy Malnutrition.

Pathways for Protein-Energy Malnutrition

GO Terms for Protein-Energy Malnutrition

Cellular components related to Protein-Energy Malnutrition according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.61 ALB CP IGF1 IL6 LEP PIGR
2 endoplasmic reticulum lumen GO:0005788 9.46 ALB CP IL6 TF
3 extracellular space GO:0005615 9.32 ALB CP GPT IGF1 IL6 LEP

Biological processes related to Protein-Energy Malnutrition according to GeneCards Suite gene sharing:

(show all 17)
id Name GO ID Score Top Affiliating Genes
1 negative regulation of apoptotic process GO:0043066 9.87 ALB IGF1 IL6 LEP
2 post-translational protein modification GO:0043687 9.81 ALB CP IL6 TF
3 platelet degranulation GO:0002576 9.71 ALB IGF1 TF
4 positive regulation of MAPK cascade GO:0043410 9.63 IGF1 IL6 LEP
5 positive regulation of protein kinase B signaling GO:0051897 9.61 IL6 LEP TNF
6 positive regulation of JAK-STAT cascade GO:0046427 9.56 IL6 LEP
7 positive regulation of chemokine production GO:0032722 9.55 IL6 TNF
8 positive regulation of smooth muscle cell proliferation GO:0048661 9.54 IGF1 IL6 TNF
9 leukocyte tethering or rolling GO:0050901 9.52 LEP TNF
10 negative regulation of glucose import GO:0046325 9.49 LEP TNF
11 positive regulation of protein import into nucleus, translocation GO:0033160 9.48 IGF1 IL6
12 epithelial cell proliferation involved in salivary gland morphogenesis GO:0060664 9.4 IL6 TNF
13 retina homeostasis GO:0001895 9.33 ALB PIGR TF
14 bone mineralization involved in bone maturation GO:0035630 9.32 IGF1 LEP
15 positive regulation of STAT protein import into nucleus GO:2000366 9.26 IL6 LEP
16 negative regulation of lipid storage GO:0010888 9.13 IL6 LEP TNF
17 cellular protein metabolic process GO:0044267 9.1 ALB CP IGF1 IL6 TF TTR

Molecular functions related to Protein-Energy Malnutrition according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.13 IGF1 IL6 LEP
2 hormone activity GO:0005179 8.8 IGF1 LEP TTR

Sources for Protein-Energy Malnutrition

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....