MCID: PRT038
MIFTS: 52

Protein-Energy Malnutrition

Categories: Metabolic diseases

Aliases & Classifications for Protein-Energy Malnutrition

MalaCards integrated aliases for Protein-Energy Malnutrition:

Name: Protein-Energy Malnutrition 12 51 41 14 69
Pem 44

Classifications:



External Ids:

Disease Ontology 12 DOID:11801
ICD10 32 E46
ICD9CM 34 263.9
MeSH 41 D011502
NCIt 46 C34952
UMLS 69 C0033677

Summaries for Protein-Energy Malnutrition

MalaCards based summary : Protein-Energy Malnutrition, also known as pem, is related to kwashiorkor and chronic fatigue syndrome, and has symptoms including emaciation and cachexia. An important gene associated with Protein-Energy Malnutrition is ALB (Albumin), and among its related pathways/superpathways are Dilated cardiomyopathy (DCM) and Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. The drugs Morphine and Naproxen have been mentioned in the context of this disorder. Affiliated tissues include prostate, liver and brain, and related phenotypes are hematopoietic system and homeostasis/metabolism

Wikipedia : 72 Protein–energy malnutrition (PEM) refers to a form of malnutrition which is defined as a range of... more...

Related Diseases for Protein-Energy Malnutrition

Diseases related to Protein-Energy Malnutrition via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 255)
# Related Disease Score Top Affiliating Genes
1 kwashiorkor 32.0 ALB GPT TF TTR
2 chronic fatigue syndrome 30.9 IGF1 IL6 TNF
3 marasmus 30.3 ALB CD79A TF TTR
4 liver cirrhosis 30.2 ALB GPT TF
5 ancylostomiasis 30.1 CP TF
6 peritonitis 29.8 ALB IL6 TNF
7 burns 29.6 ALB TNF TTR
8 alcoholic liver cirrhosis 29.6 ALB TF TNF
9 deficiency anemia 29.5 ALB CP IL6 TF
10 diarrhea 29.5 ALB CD79A TNF
11 meningitis 29.3 ALB IL6 TNF
12 viral hepatitis 29.2 ALB GPT TNF
13 alcoholic hepatitis 28.7 ALB GPT IL6 TNF
14 dilated cardiomyopathy 28.5 ALB IGF1 IL6 TNF
15 chronic kidney failure 28.3 ALB CD79A IGF1 IL6 LEP TF
16 body mass index quantitative trait locus 11 28.3 GPT IGF1 IL6 LEP TNF
17 diabetes mellitus 28.0 ALB CP IGF1 IL6 LEP TNF
18 liver disease 27.4 ALB CP GPT IL6 LEP TF
19 paramyloidosis 10.5 ALB TTR
20 cork-handlers' disease 10.5 ALB CD79A
21 ostertagiasis 10.5 ALB CD79A
22 dermatitis, atopic, 3 10.5 ALB CD79A
23 carotenemia 10.5 CD79A TTR
24 orthostatic proteinuria 10.5 ALB CD79A
25 median rhomboid glossitis 10.5 TF TTR
26 meningitis and encephalitis 10.5 ALB CP
27 decubitus ulcer 10.5 ALB TTR
28 root caries 10.5 ALB CD79A
29 parotitis 10.5 ALB CD79A
30 blepharochalasis 10.5 CD79A TTR
31 chronic graft versus host disease 10.5 ALB CD79A
32 aleutian mink disease 10.4 ALB TTR
33 ulcerative blepharitis 10.4 CD79A CP
34 chronic ulcer of skin 10.4 ALB TTR
35 diffuse glomerulonephritis 10.4 ALB CD79A
36 focal dermal hypoplasia 10.4 ALB CD79A
37 hyperthyroxinemia 10.4 ALB TTR
38 hypochromic microcytic anemia 10.4 CP TF
39 non-secretory myeloma 10.4 ALB CD79A
40 euthyroid sick syndrome 10.3 ALB IL6
41 ariboflavinosis 10.3 ALB TF
42 testicular yolk sac tumor 10.3 ALB TF TTR
43 aging 10.3
44 amyloid tumor 10.3 CD79A TTR
45 yellow nail syndrome 10.3 ALB CD79A TF
46 central precocious puberty 10.3 IGF1 LEP
47 lipoid nephrosis 10.3 ALB CD79A TF
48 polyclonal hypergammaglobulinemia 10.3 CD79A IL6
49 thyroiditis 10.3
50 capillary leak syndrome 10.3 ALB IL6

Comorbidity relations with Protein-Energy Malnutrition via Phenotypic Disease Network (PDN): (show top 50) (show all 153)


Acquired Thrombocytopenia Active Peptic Ulcer Disease
Acute Conjunctivitis Acute Cystitis
Acute Kidney Failure Acute Myocardial Infarction
Acute Pancreatitis Acute Vascular Insufficiency of Intestine
Alcohol Abuse Alcoholic Hepatitis
Alcoholic Liver Cirrhosis Alcoholic Neuropathy
Alzheimer Disease Anxiety
Atrophic Gastritis Bacteremia 2
Biliary Tract Neoplasm Bronchiectasis
Bronchitis Bronchopneumonia
Bulimia Nervosa 2 Bullous Pemphigoid
Candidiasis Cardiac Arrest
Cecal Benign Neoplasm Celiac Disease 1
Cerebral Atherosclerosis Cerebral Degeneration
Cerebrovascular Disease Cholangitis
Cholecystitis Cholestasis
Chronic Intestinal Vascular Insufficiency Chronic Kidney Failure
Chronic Myocardial Ischemia Chronic Pulmonary Heart Disease
Chronic Ulcer of Skin Chylomicron Retention Disease
Colorectal Cancer Conjunctivitis
Crohn's Disease Cystitis
Decubitus Ulcer Deficiency Anemia
Dental Caries Dermatomycosis
Disseminated Intravascular Coagulation Duodenum Cancer
Dyskinesia of Esophagus Dysthymic Disorder

Graphical network of the top 20 diseases related to Protein-Energy Malnutrition:



Diseases related to Protein-Energy Malnutrition

Symptoms & Phenotypes for Protein-Energy Malnutrition

UMLS symptoms related to Protein-Energy Malnutrition:


emaciation, cachexia

MGI Mouse Phenotypes related to Protein-Energy Malnutrition:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.86 TNF CD79A CP IGF1 IL6 LEP
2 homeostasis/metabolism MP:0005376 9.85 CD79A TTR CP IGF1 IL6 LEP
3 adipose tissue MP:0005375 9.72 TNF CP IGF1 IL6 LEP
4 liver/biliary system MP:0005370 9.43 ALB TNF CD79A CP IL6 LEP
5 neoplasm MP:0002006 9.1 CD79A IGF1 IL6 LEP ALB TNF

Drugs & Therapeutics for Protein-Energy Malnutrition

Drugs for Protein-Energy Malnutrition (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 177)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Morphine Approved, Investigational Phase 4,Phase 3 57-27-2 5288826
2
Naproxen Approved, Vet_approved Phase 4 22204-53-1 156391 1302
3
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
4
Buprenorphine Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 3 52485-79-7 644073 40400
5
chenodeoxycholic acid Approved Phase 4 474-25-9 10133
6
Naltrexone Approved, Investigational, Vet_approved Phase 4 16590-41-3 5360515
7 Analgesics Phase 4,Phase 3,Phase 2
8 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2
9 Analgesics, Opioid Phase 4,Phase 3,Phase 2
10 Antirheumatic Agents Phase 4,Phase 3,Phase 2
11 Central Nervous System Depressants Phase 4,Phase 3,Phase 2
12 Narcotics Phase 4,Phase 3,Phase 2
13 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
14 Antimetabolites Phase 4,Phase 2,Phase 1
15 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2
16 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 3
17 Cyclooxygenase Inhibitors Phase 4
18 Narcotic Antagonists Phase 4,Phase 3
19 Opiate Alkaloids Phase 4
20 HIV Protease Inhibitors Phase 4,Phase 2
21
protease inhibitors Phase 4,Phase 2
22 Gastrointestinal Agents Phase 4,Phase 2
23 Cystatins Phase 4
24 Anticholesteremic Agents Phase 4
25 Bile Acids and Salts Phase 4
26 Cathartics Phase 4
27 Colesevelam Hydrochloride Phase 4
28 Glucagon-Like Peptide 1 Phase 4
29 Hypolipidemic Agents Phase 4
30 Laxatives Phase 4
31 Lipid Regulating Agents Phase 4
32 Liver Extracts Phase 4
33 cysteine Nutraceutical Phase 4
34 isoleucine Nutraceutical Phase 4
35 leucine Nutraceutical Phase 4
36 valine Nutraceutical Phase 4
37
Acetaminophen Approved Phase 3,Phase 2 103-90-2 1983
38
Pentoxifylline Approved, Investigational Phase 3 6493-05-6 4740
39
Chlorhexidine Approved, Vet_approved Phase 3 55-56-1 2713 9552079
40
Lubiprostone Approved, Investigational Phase 3 136790-76-6 656719
41
Sodium oxybate Approved Phase 3 502-85-2 5360545
42
Hydrocodone Approved, Illicit Phase 3 125-29-1 5284569
43 Anti-Infective Agents Phase 3,Phase 2,Phase 1
44 Dermatologic Agents Phase 3,Phase 2
45 Adjuvants, Anesthesia Phase 3,Phase 2
46 Anesthetics Phase 3,Phase 2
47 Antioxidants Phase 3
48 Phosphodiesterase Inhibitors Phase 3
49 Platelet Aggregation Inhibitors Phase 3
50 Protective Agents Phase 3

Interventional clinical trials:

(show top 50) (show all 81)

# Name Status NCT ID Phase Drugs
1 Egg Albumin-Based Protein Supplement Versus Renal-specific Supplement in Hemodialysis Patients Unknown status NCT01981083 Phase 4
2 Controlled-Release Oxycodone Versus Naproxen at Home After Ambulatory Surgery: A Randomized Controlled Trial Completed NCT02152592 Phase 4 PCM/Oxy1;PCM/Oxy2
3 Integration of Buprenorphine Into HIV Clinical Settings - Primary Care Model (PCM) Completed NCT00798538 Phase 4
4 Kidney Response to Sepsis Affects Angiogenic Balance and Likelihood of CCI and PICS Recruiting NCT02276066 Phase 4 Iohexol
5 Effects of Bile Acids and Bile Acid Sequestrants on GLP-1 Secretion After Roux-en-Y Gastric Bypass Recruiting NCT02876484 Phase 4 Colesevelam;Chenodeoxycholic Acid
6 Branched-chain Amino Acid (BCAA) on Progression of Advanced Liver Disease Active, not recruiting NCT02837302 Phase 4 Livact
7 Conversion to Embeda With Rescue Trial Terminated NCT01179191 Phase 4 morphine sulfate and naltrexone hydrochloride (EMBEDA)
8 Use of Morphine Gel Topically in Patients With Stage 2-3 Wounds Unknown status NCT00755989 Phase 3 morphine topical gel;placebo
9 Post-Approval Clinical Trial of the PCM® Cervical Disc Completed NCT01905930 Phase 3
10 PCM Cervical Disc System Completed NCT00578812 Phase 3
11 Efficacy,Safety and Quality of Life After TOOKAD® Soluble VTP for Localized Prostate Cancer Completed NCT01875393 Phase 3 TOOKAD® Soluble
12 Efficacy and Safety Study of TOOKAD® Soluble for Localised Prostate Cancer Compared to Active Surveillance. Completed NCT01310894 Phase 3 TOOKAD® Soluble
13 Anit-Inflammatory and Anti-Oxidative Nutrition in Dialysis Patients Completed NCT00561093 Phase 3 pentoxiphylline;Placebo pill imitating pentoxiphylline
14 Newborn Kit to Save Lives and Brains in Kenya Completed NCT02208960 Phase 3
15 Opioid-induced Bowel Dysfunction Pivotal Assessment of Lubiprostone Completed NCT00597428 Phase 3 Lubiprostone;Placebo
16 Safety and Efficacy Study of Xyrem® (Sodium Oxybate) in Subjects With Fibromyalgia. Completed NCT00423605 Phase 3 Xyrem®
17 A Safety and Efficacy Study of Xyrem® in Subjects With Fibromyalgia Completed NCT00371137 Phase 3 Xyrem®;Placebo
18 Safety and Efficacy of Dose Conversion From Vicodin® to Buprenorphine Transdermal System (Butrans™) in Subjects With OA Pain Completed NCT00312572 Phase 3 Buprenorphine transdermal patch
19 Paracetamol for Intrapartum Analgesia Unknown status NCT02578251 Phase 2 Paracetamol;Pethidine
20 Whole Body Cooling Using Phase Changing Material Unknown status NCT01138176 Phase 1, Phase 2
21 Cyclophosphamide Versus Methotrexate for Remission Maintenance in Systemic Necrotizing Vasculitides Unknown status NCT00751517 Phase 2 Methotrexate;Cyclophosphamide
22 Study of Efficacy of Induction Chemotherapy With Gemcitabine and Carboplatin for Operable Non-small-cell Lung Cancer Before Surgery Unknown status NCT00563160 Phase 2 gemcitabine, carboplatin
23 Violence and Stress Assessment (ViStA) Project to Improve Post Traumatic Stress Disorder Management in Primary Care Completed NCT01401101 Phase 2
24 Study Using WST11 in Patients With Localized Prostate Cancer Completed NCT00975429 Phase 2 WST11;WST11
25 Safety and Tolerability Study Using WST11 In Patients With Localized Prostate Cancer Completed NCT00946881 Phase 1, Phase 2 WST 11 -mediated -VTP
26 Study of WST11 in Patients With Localized Prostate Cancer Completed NCT00707356 Phase 2 WST11
27 Evaluation of Cortisol Resistance in Young Sedentary and Endurance-Trained Men Completed NCT01294319 Phase 2 Mifepristone;Placebo;Spironolactone;Combined;Dexamethasone
28 PCM-075 in Combination With Either Low-dose Cytarabine or Decitabine in Adult Patients With Acute Myeloid Leukemia (AML). Recruiting NCT03303339 Phase 1, Phase 2 PCM-075;Cytarabine;Decitabine
29 Study of the Efficacy, Safety and Quality of Life After TOOKAD® Soluble (VTP) for Intermediate Risk Prostate Cancer. Recruiting NCT03315754 Phase 2 TOOKAD Soluble 4 mg/kg
30 Collection of Transplant Stem Cells for Plasma Cell Myeloma Active, not recruiting NCT01547806 Phase 2 Filgrastim;Plerixafor
31 PCM-075 in Combination With Abiraterone and Prednisone in Adult Patients With Metastatic Castration-Resistant Prostate Cancer Not yet recruiting NCT03414034 Phase 2 PCM-075;Abiraterone;Prednisone
32 Acceptability and Efficacy of 'Fish Surimi Peptide' in Under Five Children Suffering From Moderate Acute Malnutrition Completed NCT02272543 Phase 1
33 Phase 1 Study of LOXO-292 in Patients With Advanced Solid Tumors, RET-Fusion Lung Cancer and Medullary Thyroid Cancer Recruiting NCT03157128 Phase 1 LOXO-292
34 A Phase I Trial Evaluating mFOLFOX6 and Avastin With Nexavar as First-Line Treatment for Metastatic Colorectal Cancer Terminated NCT00779311 Phase 1 sorafenib;bevacizumab;mFOLFOX6 regimen
35 The Impact of Perioperational Malnutrition on the Cost on Gastroenterological Cancer Patients Unknown status NCT00987883
36 Evaluation of the Effectiveness of a Protein Pulse-Feeding Pattern in Elderly Patients Completed NCT00135590
37 Clinical Performance of the Embrace Isothermal Mattress Completed NCT01425086
38 Study of Antioxidants and Oxidants in Malnourished Children Completed NCT00069134
39 Enhancing HIV Prevention by Using Behavioral Intervention Among HIV-Infected Men Completed NCT00231972
40 Energy Dense Formula to People Living in Old Peoples Home Completed NCT01259999
41 aCGH Impacts Survival in Plasma Cell PTLD Completed NCT02984215
42 Role of Nutrition in Patients Over 75 Years of Age With Stroke Completed NCT02856009
43 Bioelectrical Impedance Vector Analysis in Cirrhotic Patients Completed NCT01603953
44 Collaborative Targeted Case Management in Improving Functional Status in Patients With Stage III-IV Cancer Completed NCT01721343
45 Visibility of Lesion Characteristics With Phase Contrast Mammography Completed NCT00467727
46 Two Techniques for Root Coverage With a Xenogeneic Collagen Matrix Completed NCT02129504
47 MostCare Versus Echo-Doppler for Cardiac Output Measurement Completed NCT01678950
48 Adding Malabsorption for Failed Gastric Bypass Completed NCT01040481
49 A Nutrition/Hygiene Education Program for the Prevention of Child Malnutrition in Rural Kenya Completed NCT01679535
50 Chronic Marginal Ulcers After Gastric Bypass Completed NCT01041079

Search NIH Clinical Center for Protein-Energy Malnutrition

Cochrane evidence based reviews: protein-energy malnutrition

Genetic Tests for Protein-Energy Malnutrition

Anatomical Context for Protein-Energy Malnutrition

MalaCards organs/tissues related to Protein-Energy Malnutrition:

38
Prostate, Liver, Brain, Bone, Thyroid, Kidney, Testes

Publications for Protein-Energy Malnutrition

Articles related to Protein-Energy Malnutrition:

(show top 50) (show all 537)
# Title Authors Year
1
Protein-Energy Malnutrition Exacerbates Stroke-Induced Forelimb Abnormalities and Dampens Neuroinflammation. ( 29397529 )
2018
2
Why Is the Skeleton Still in the Hospital Closet? A Look at the Complex Aetiology of Protein-Energy Malnutrition and Its Implications for the Nutrition Care Team. ( 29300418 )
2018
3
An Adjuvanted A(H5N1) Subvirion Vaccine Elicits Virus-Specific Antibody Response and Improves Protection Against Lethal Influenza Viral Challenge in Mouse Model of Protein Energy Malnutrition. ( 28934453 )
2017
4
Protein energy malnutrition alters mucosal IgA responses and reduces mucosal vaccine efficacy in mice. ( 28860040 )
2017
5
Genetic Engineering: A Possible Strategy for Protein-Energy Malnutrition Regulation. ( 28828714 )
2017
6
Protein blend ingestion before allogeneic stem cell transplantation improves protein-energy malnutrition in patients with leukemia. ( 28964569 )
2017
7
A systematic review and meta-analysis of the criterion validity of nutrition assessment tools for diagnosing protein-energy malnutrition in the older community setting (the MACRo study). ( 29102322 )
2017
8
Honey can repairing damage of liver tissue due to protein energy malnutrition through induction of endogenous stem cells. ( 28717326 )
2017
9
Does protein energy malnutrition affect the outcome in Tunisian cirrhotic patients? ( 27532543 )
2016
10
Protein-energy malnutrition is frequent and precocious in children with cri du chat syndrome. ( 26872355 )
2016
11
Factors Associated With Protein-energy Malnutrition in Chronic Liver Disease: Analysis Using Indirect Calorimetry. ( 26765430 )
2016
12
The Arid Melancholy-Netherton Syndrome With Protein Energy Malnutrition. ( 27190931 )
2016
13
Protein energy malnutrition associates with different types of hearing impairments in toddlers: Anemia increases cochlear dysfunction. ( 27240492 )
2016
14
Convergence of a diabetes mellitus, protein energy malnutrition, and TB epidemic: the neglected elderly population. ( 27456231 )
2016
15
Protein-energy malnutrition in the rehabilitation setting: Evidence to improve identification. ( 26921933 )
2016
16
Serum hyaluronic acid predicts protein-energy malnutrition in chronic hepatitis C. ( 27311000 )
2016
17
Prognostic significance of low skeletal muscle mass compared with protein-energy malnutrition in liver cirrhosis. ( 27862791 )
2016
18
Protein-Energy Malnutrition Causes Deficits in Motor Function in Adult Male Rats. ( 26423735 )
2015
19
Protein-energy malnutrition: a risk factor for various ailments. ( 24915388 )
2015
20
Protein Energy Malnutrition during Vaccination Has Limited Influence on Vaccine Efficacy but Abolishes Immunity if Administered during Mycobacterium tuberculosis Infection. ( 25754202 )
2015
21
Leucine Supplementation Improves Acquired Growth Hormone Resistance in Rats with Protein-Energy Malnutrition. ( 25909895 )
2015
22
Seroprevalence rate of Poliovirus antibodies among the Healthy and Protein Energy Malnutrition children. ( 26101500 )
2015
23
Serum vitamin D status in children with protein-energy malnutrition admitted to a national referral hospital in Uganda. ( 26346815 )
2015
24
Protein-energy malnutrition at mid-adulthood does not imprint long-term metabolic consequences in male rats. ( 26133298 )
2015
25
Evaluation of dental age in protein energy malnutrition children. ( 26538919 )
2015
26
Protein Energy-Malnutrition: Does the In Vitro Zinc Sulfate Supplementation Improve Chromosomal Damage Repair? ( 25262017 )
2014
27
Determinants of protein-energy malnutrition in community dwelling older adults: A systematic review of observational studies. ( 25257179 )
2014
28
Protein-energy malnutrition developing after global brain ischemia induces an atypical acute-phase response and hinders expression of GAP-43. ( 25259609 )
2014
29
Prevalence of protein-energy malnutrition in hospital patients over 75 years of age admitted for hip fracture. ( 24998085 )
2014
30
Free radicals and antioxidant status in protein energy malnutrition. ( 24790610 )
2014
31
Protein energy malnutrition in India: the plight of our under five children. ( 24791240 )
2014
32
Maternal protein-energy malnutrition during early pregnancy in sheep impacts the fetal ornithine cycle to reduce fetal kidney microvascular development. ( 25077559 )
2014
33
Protein energy malnutrition increases arginase activity in monocytes and macrophages. ( 25392710 )
2014
34
Protein-energy Malnutrition in Goitrous Schoolchildren of Isfahan, Iran. ( 24932384 )
2014
35
Porcine placenta mitigates protein-energy malnutrition-induced fatigue. ( 24035056 )
2013
36
Cystic fibrosis: from protein-energy malnutrition to obesity with dyslipidemia. ( 24800027 )
2013
37
Acquired protein energy malnutrition in glutaric acidemia. ( 23330977 )
2013
38
Hepatoprotective and nephroprotective effects of Cnidoscolus aconitifolius in protein energy malnutrition induced liver and kidney damage. ( 24174819 )
2013
39
Rutin (quercetin rutinoside) induced protein-energy malnutrition in chronic kidney disease, but quercetin acted beneficially. ( 23876017 )
2013
40
Protein-energy malnutrition alters IgA responses to rotavirus vaccination and infection but does not impair vaccine efficacy in mice. ( 24200975 )
2013
41
Protein energy malnutrition decreases immunity and increases susceptibility to influenza infection in mice. ( 22949306 )
2013
42
A comparison of the full Mini Nutritional Assessment, short-form Mini Nutritional Assessment, and Subjective Global Assessment to predict the risk of protein-energy malnutrition in patients on peritoneal dialysis: a cross-sectional study. ( 23000089 )
2013
43
Protein-energy malnutrition induces an aberrant acute-phase response and modifies the circadian rhythm of core temperature. ( 23855272 )
2013
44
Effect of a probiotic fermented milk on the thymus in Balb/c mice under non-severe protein-energy malnutrition. ( 23286742 )
2013
45
Relation of oxidative stress, zinc and alkaline phosphatase in protein energy malnutrition. ( 23373727 )
2013
46
Methicillin-resistant Staphylococcus aureus carriage in infants with protein-energy malnutrition. ( 24502042 )
2013
47
Effect of early childhood protein-energy malnutrition on permanent dentition dental caries. ( 24255941 )
2013
48
Missed opportunities in the diagnosis and management of protein energy malnutrition among children under 5 years in Wakiso district, Uganda. ( 25035810 )
2013
49
A narrative review of recent progress in understanding the relationship between tuberculosis and protein energy malnutrition. ( 23942176 )
2013
50
Hematologic and Bone Marrow Changes in Children with Protein-Energy Malnutrition. ( 23987917 )
2013

Variations for Protein-Energy Malnutrition

Expression for Protein-Energy Malnutrition

Search GEO for disease gene expression data for Protein-Energy Malnutrition.

Pathways for Protein-Energy Malnutrition

GO Terms for Protein-Energy Malnutrition

Cellular components related to Protein-Energy Malnutrition according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.61 ALB CP IGF1 IL6 LEP PIGR
2 endoplasmic reticulum lumen GO:0005788 9.46 ALB CP IL6 TF
3 extracellular space GO:0005615 9.32 ALB CP GPT IGF1 IL6 LEP

Biological processes related to Protein-Energy Malnutrition according to GeneCards Suite gene sharing:

(show all 17)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of apoptotic process GO:0043066 9.86 ALB IGF1 IL6 LEP
2 post-translational protein modification GO:0043687 9.8 ALB CP IL6 TF
3 platelet degranulation GO:0002576 9.69 ALB IGF1 TF
4 regulation of receptor activity GO:0010469 9.65 IGF1 IL6 LEP TNF TTR
5 positive regulation of MAPK cascade GO:0043410 9.63 IGF1 IL6 LEP
6 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.61 IGF1 IL6 LEP
7 positive regulation of smooth muscle cell proliferation GO:0048661 9.58 IGF1 IL6 TNF
8 positive regulation of cytokine production GO:0001819 9.57 LEP TNF
9 positive regulation of chemokine production GO:0032722 9.55 IL6 TNF
10 positive regulation of JAK-STAT cascade GO:0046427 9.54 IL6 LEP
11 leukocyte tethering or rolling GO:0050901 9.52 LEP TNF
12 negative regulation of glucose import GO:0046325 9.48 LEP TNF
13 positive regulation of STAT protein import into nucleus GO:2000366 9.37 IL6 LEP
14 retina homeostasis GO:0001895 9.33 ALB PIGR TF
15 bone mineralization involved in bone maturation GO:0035630 9.32 IGF1 LEP
16 negative regulation of lipid storage GO:0010888 9.13 IL6 LEP TNF
17 cellular protein metabolic process GO:0044267 9.1 ALB CP IGF1 IL6 TF TTR

Molecular functions related to Protein-Energy Malnutrition according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.13 IGF1 IL6 LEP
2 hormone activity GO:0005179 8.8 IGF1 LEP TTR

Sources for Protein-Energy Malnutrition

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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