MCID: PRT038
MIFTS: 48

Protein-Energy Malnutrition

Categories: Metabolic diseases

Aliases & Classifications for Protein-Energy Malnutrition

MalaCards integrated aliases for Protein-Energy Malnutrition:

Name: Protein-Energy Malnutrition 12 52 42 14 69
Pem 45

Classifications:



External Ids:

Disease Ontology 12 DOID:11801
ICD10 33 E46
ICD9CM 35 263.9
MeSH 42 D011502
NCIt 47 C34952
UMLS 69 C0033677

Summaries for Protein-Energy Malnutrition

MalaCards based summary : Protein-Energy Malnutrition, also known as pem, is related to hypervitaminosis a and malaria, and has symptoms including cachexia and emaciation. An important gene associated with Protein-Energy Malnutrition is ALB (Albumin), and among its related pathways/superpathways are Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Morphine and Naproxen have been mentioned in the context of this disorder. Affiliated tissues include liver, prostate and brain, and related phenotypes are homeostasis/metabolism and hematopoietic system

Wikipedia : 72 Protein–energy malnutrition (PEM) or protein–calorie malnutrition refers to a form of malnutrition which... more...

Related Diseases for Protein-Energy Malnutrition

Diseases related to Protein-Energy Malnutrition via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 260)
id Related Disease Score Top Affiliating Genes
1 hypervitaminosis a 30.7 CD79A TTR
2 malaria 28.1 ALB HP IL6 TNF
3 kwashiorkor 11.3
4 chronic fatigue syndrome 10.8
5 midface dysplasia 10.8 ALB TTR
6 early-onset severe reducing body myopathy, x-linked 10.8 ALB TTR
7 atopic dermatitis 5 10.8 ALB CD79A
8 microinvasive cervical squamous cell carcinoma 10.8 ALB CD79A
9 ovary transitional cell carcinoma 10.8 ALB CD79A
10 speech and communication disorders 10.7 ALB TTR
11 non-congenital cyst of kidney 10.7 ALB CD79A
12 milker's nodule 10.7 ALB TTR
13 bacteriuria 10.7 TF TTR
14 infertility due to extratesticular cause 10.7 ALB CD79A
15 motion sickness 10.7 ALB TTR
16 necrobiosis lipoidica 10.7 CD79A TTR
17 chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids 10.7 ALB CD79A
18 immune-complex glomerulonephritis 10.7 ALB CD79A
19 macular dystrophy, patterned, 1 10.7 TF TTR
20 tarp syndrome 10.7 ALB CD79A
21 hemoglobinopathy 10.6 ALB TTR
22 adrenal gland disease 10.6 ALB CD79A
23 lung lymphoma 10.6 CD79A TTR
24 complement component 8 deficiency 10.6 IGF1 LEP
25 chronic lymphocytic leukemia 10.5 HP TTR
26 acute gonococcal cervicitis 10.5 ALB CD79A
27 pancreatic cystadenocarcinoma 10.5 ALB GPT
28 cryptorchidism arachnodactyly mental retardation 10.5 CD79A HP
29 pellagra 10.5 ALB TF
30 kidney carcinoma in situ 10.5 CD79A HP
31 adie pupil 10.5 ALB CD79A TF
32 spastic monoplegia 10.5 ALB CD79A TF
33 cerebral sarcoidosis 10.4 ALB TF
34 xeroderma pigmentosum, group f 10.4 HP TF
35 congenital nonspherocytic hemolytic anemia 10.4 ALB IL6
36 generalized atherosclerosis 10.4 CD79A IL6
37 intramuscular hemangioma 10.4 ALB LEP TF
38 shigellosis 10.4 CD79A HP
39 labyrinthine bilateral reactive loss 10.3 ALB IL6
40 vulvar sarcoma 10.3 ALB IL6
41 infertility 10.3 ALB HP TTR
42 adult neuronal ceroid lipofuscinosis 10.3 IL6 LEP
43 peroneal neuropathy 10.3 ALB IGF1 LEP
44 congenital dyserythropoietic anemia 10.3 ALB TNF
45 tonsil cancer 10.3 ALB GPT
46 spinocerebellar ataxia 8 10.3 ALB GPT TF
47 scleredema adultorum 10.3 IL6 LEP
48 tinf2-related dyskeratosis congenita 10.2 IGF1 TF
49 methylmalonic aciduria and homocystinuria type cblg 10.2 CD79A GPT TF
50 lymphedema 10.2 ALB GPT TF

Comorbidity relations with Protein-Energy Malnutrition via Phenotypic Disease Network (PDN): (show top 50) (show all 150)


Acquired Thrombocytopenia Active Peptic Ulcer Disease
Acute Conjunctivitis Acute Cystitis
Acute Kidney Failure Acute Myocardial Infarction
Acute Pancreatitis Alcohol Abuse
Alcoholic Hepatitis Alcoholic Liver Cirrhosis
Alcoholic Neuropathy Alzheimer Disease
Amyotrophic Lateral Sclerosis 1 Anorexia Nervosa
Anxiety Disorder Aplastic Anemia
Atrophic Gastritis Bacteremia
Biliary Tract Neoplasm Bronchiectasis
Bronchitis Bronchopneumonia
Bullous Pemphigoid Candidiasis
Cardiac Arrest Cecal Benign Neoplasm
Celiac Disease Cerebral Atherosclerosis
Cerebral Degeneration Cerebrovascular Disease
Cholangitis Cholecystitis
Cholestasis Chronic Kidney Failure
Chronic Myocardial Ischemia Chronic Pulmonary Heart Disease
Chronic Ulcer of Skin Chylomicron Retention Disease
Colorectal Cancer Conjunctivitis
Crohn's Disease Cystitis
Decubitus Ulcer Deficiency Anemia
Dental Caries Dermatomycosis
Disseminated Intravascular Coagulation Duodenum Cancer
Dyskinesia of Esophagus Dysthymic Disorder

Graphical network of the top 20 diseases related to Protein-Energy Malnutrition:



Diseases related to Protein-Energy Malnutrition

Symptoms & Phenotypes for Protein-Energy Malnutrition

UMLS symptoms related to Protein-Energy Malnutrition:


cachexia, emaciation

MGI Mouse Phenotypes related to Protein-Energy Malnutrition:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.96 ALB CD79A HP IGF1 IL6 LEP
2 hematopoietic system MP:0005397 9.92 PIGR TF TNF CD79A HP IGF1
3 liver/biliary system MP:0005370 9.63 ALB CD79A HP IL6 LEP TNF
4 neoplasm MP:0002006 9.5 TNF ALB CD79A HP IGF1 IL6
5 renal/urinary system MP:0005367 9.1 ALB CD79A HP IGF1 IL6 LEP

Drugs & Therapeutics for Protein-Energy Malnutrition

Drugs for Protein-Energy Malnutrition (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 146)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Morphine Approved, Investigational Phase 4,Phase 3 57-27-2 5288826
2
Naproxen Approved, Vet_approved Phase 4 22204-53-1 1302 156391
3
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
4
Buprenorphine Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 3 52485-79-7 40400 644073
5
chenodeoxycholic acid Approved Phase 4 474-25-9 10133
6
Naltrexone Approved, Investigational, Vet_approved Phase 4 16590-41-3 5360515
7 Analgesics Phase 4,Phase 3,Phase 2
8 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2
9 Analgesics, Opioid Phase 4,Phase 3,Phase 2
10 Antirheumatic Agents Phase 4,Phase 3,Phase 2
11 Central Nervous System Depressants Phase 4,Phase 3,Phase 2
12 Narcotics Phase 4,Phase 3,Phase 2
13 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
14 Antimetabolites Phase 4,Phase 2
15 Anti-Inflammatory Agents Phase 4,Phase 3
16 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 3
17 Cyclooxygenase Inhibitors Phase 4
18 Narcotic Antagonists Phase 4,Phase 3
19 Opiate Alkaloids Phase 4
20 Liver Extracts Phase 4
21 Cystatins Phase 4
22 HIV Protease Inhibitors Phase 4
23
protease inhibitors Phase 4
24 Anticholesteremic Agents Phase 4
25 Bile Acids and Salts Phase 4
26 Cathartics Phase 4
27 Colesevelam Hydrochloride Phase 4
28 Gastrointestinal Agents Phase 4
29 Glucagon-Like Peptide 1 Phase 4
30 Hypolipidemic Agents Phase 4
31 Laxatives Phase 4
32 Lipid Regulating Agents Phase 4
33 cysteine Nutraceutical Phase 4
34 isoleucine Nutraceutical Phase 4
35 leucine Nutraceutical Phase 4
36 valine Nutraceutical Phase 4
37
Acetaminophen Approved Phase 3,Phase 2 103-90-2 1983
38
Pentoxifylline Approved, Investigational Phase 3 6493-05-6 4740
39
Chlorhexidine Approved, Vet_approved Phase 3 55-56-1 9552079 2713
40
Lubiprostone Approved, Investigational Phase 3 136790-76-6 656719
41
Sodium oxybate Approved Phase 3 502-85-2 5360545
42
Hydrocodone Approved, Illicit Phase 3 125-29-1 5284569
43 Anti-Infective Agents Phase 3,Phase 2
44 Dermatologic Agents Phase 3,Phase 2
45 Adjuvants, Anesthesia Phase 3,Phase 2
46 Anesthetics Phase 3,Phase 2
47 Antioxidants Phase 3
48 Phosphodiesterase Inhibitors Phase 3
49 Platelet Aggregation Inhibitors Phase 3
50 Protective Agents Phase 3

Interventional clinical trials:

(show top 50) (show all 85)

id Name Status NCT ID Phase Drugs
1 Egg Albumin-Based Protein Supplement Versus Renal-specific Supplement in Hemodialysis Patients Unknown status NCT01981083 Phase 4
2 Controlled-Release Oxycodone Versus Naproxen at Home After Ambulatory Surgery: A Randomized Controlled Trial Completed NCT02152592 Phase 4 PCM/Oxy1;PCM/Oxy2
3 Integration of Buprenorphine Into HIV Clinical Settings - Primary Care Model (PCM) Completed NCT00798538 Phase 4
4 Malnutrition in Gastroenterology Patients Completed NCT00168935 Phase 4 Fresubin protein energy Drink (CAVE! nutritional intervention)
5 Nutritional Intervention in Malnourished Elderly Patients Completed NCT00417508 Phase 4
6 Enteral Nutrition in Liver Cirrhosis Completed NCT00168961 Phase 4
7 Kidney Response to Sepsis Affects Angiogenic Balance and Likelihood of CCI and PICS Recruiting NCT02276066 Phase 4 Iohexol
8 Effects of Bile Acids and Bile Acid Sequestrants on GLP-1 Secretion After Roux-en-Y Gastric Bypass Recruiting NCT02876484 Phase 4 Colesevelam;Chenodeoxycholic Acid
9 Branched-chain Amino Acid (BCAA) on Progression of Advanced Liver Disease Active, not recruiting NCT02837302 Phase 4 Livact
10 Conversion to Embeda With Rescue Trial Terminated NCT01179191 Phase 4 morphine sulfate and naltrexone hydrochloride (EMBEDA)
11 Use of Morphine Gel Topically in Patients With Stage 2-3 Wounds Unknown status NCT00755989 Phase 3 morphine topical gel;placebo
12 Post-Approval Clinical Trial of the PCM® Cervical Disc Completed NCT01905930 Phase 3
13 PCM Cervical Disc System Completed NCT00578812 Phase 3
14 Efficacy,Safety and Quality of Life After TOOKAD® Soluble VTP for Localized Prostate Cancer Completed NCT01875393 Phase 3 TOOKAD® Soluble
15 Efficacy and Safety Study of TOOKAD® Soluble for Localised Prostate Cancer Compared to Active Surveillance. Completed NCT01310894 Phase 3 TOOKAD® Soluble
16 Anit-Inflammatory and Anti-Oxidative Nutrition in Dialysis Patients Completed NCT00561093 Phase 3 pentoxiphylline;Placebo pill imitating pentoxiphylline
17 Newborn Kit to Save Lives and Brains in Kenya Completed NCT02208960 Phase 3
18 Opioid-induced Bowel Dysfunction Pivotal Assessment of Lubiprostone Completed NCT00597428 Phase 3 Lubiprostone;Placebo
19 Safety and Efficacy Study of Xyrem® (Sodium Oxybate) in Subjects With Fibromyalgia. Completed NCT00423605 Phase 3 Xyrem®
20 A Safety and Efficacy Study of Xyrem® in Subjects With Fibromyalgia Completed NCT00371137 Phase 3 Xyrem®;Placebo
21 Safety and Efficacy of Dose Conversion From Vicodin® to Buprenorphine Transdermal System (Butrans™) in Subjects With OA Pain Completed NCT00312572 Phase 3 Buprenorphine transdermal patch
22 Protein-energy Oral Supplementation Enriched With Omega-3 Fatty Acids in Cardiac Cachexia Terminated NCT00748332 Phase 3
23 Whole Body Cooling Using Phase Changing Material Unknown status NCT01138176 Phase 1, Phase 2
24 Cyclophosphamide Versus Methotrexate for Remission Maintenance in Systemic Necrotizing Vasculitides Unknown status NCT00751517 Phase 2 Methotrexate;Cyclophosphamide
25 Paracetamol for Intrapartum Analgesia Unknown status NCT02578251 Phase 2 Paracetamol;Pethidine
26 Study of Efficacy of Induction Chemotherapy With Gemcitabine and Carboplatin for Operable Non-small-cell Lung Cancer Before Surgery Unknown status NCT00563160 Phase 2 gemcitabine, carboplatin
27 Violence and Stress Assessment (ViStA) Project to Improve Post Traumatic Stress Disorder Management in Primary Care Completed NCT01401101 Phase 2
28 Study Using WST11 in Patients With Localized Prostate Cancer Completed NCT00975429 Phase 2 WST11;WST11
29 Safety and Tolerability Study Using WST11 In Patients With Localized Prostate Cancer Completed NCT00946881 Phase 1, Phase 2 WST 11 -mediated -VTP
30 Study of WST11 in Patients With Localized Prostate Cancer Completed NCT00707356 Phase 2 WST11
31 Collection of Transplant Stem Cells for Plasma Cell Myeloma Active, not recruiting NCT01547806 Phase 2 Filgrastim;Plerixafor
32 PCM-075 in Combination With Either Low-dose Cytarabine or Decitabine in Adult Patients With Acute Myeloid Leukemia (AML). Not yet recruiting NCT03303339 Phase 1, Phase 2 PCM-075;Cytarabine;Decitabine
33 NutFish and Nutrient Supplementation in Pregnancy Class to Improve Maternal and Birth Outcomes Not yet recruiting NCT02959125 Phase 2
34 Acceptability and Efficacy of 'Fish Surimi Peptide' in Under Five Children Suffering From Moderate Acute Malnutrition Completed NCT02272543 Phase 1
35 Phase 1 Study of LOXO-292 in Patients With Advanced Solid Tumors, RET-Fusion Lung Cancer and Medullary Thyroid Cancer Recruiting NCT03157128 Phase 1 LOXO-292
36 A Phase I Trial Evaluating mFOLFOX6 and Avastin With Nexavar as First-Line Treatment for Metastatic Colorectal Cancer Terminated NCT00779311 Phase 1 sorafenib;bevacizumab;mFOLFOX6 regimen
37 The Impact of Perioperational Malnutrition on the Cost on Gastroenterological Cancer Patients Unknown status NCT00987883
38 Evaluation of the Effectiveness of a Protein Pulse-Feeding Pattern in Elderly Patients Completed NCT00135590
39 Clinical Performance of the Embrace Isothermal Mattress Completed NCT01425086
40 Study of Antioxidants and Oxidants in Malnourished Children Completed NCT00069134
41 Energy Dense Formula to People Living in Old Peoples Home Completed NCT01259999
42 Enhancing HIV Prevention by Using Behavioral Intervention Among HIV-Infected Men Completed NCT00231972
43 aCGH Impacts Survival in Plasma Cell PTLD Completed NCT02984215
44 Role of Nutrition in Patients Over 75 Years of Age With Stroke Completed NCT02856009
45 Bioelectrical Impedance Vector Analysis in Cirrhotic Patients Completed NCT01603953
46 Visibility of Lesion Characteristics With Phase Contrast Mammography Completed NCT00467727
47 Two Techniques for Root Coverage With a Xenogeneic Collagen Matrix Completed NCT02129504
48 MostCare Versus Echo-Doppler for Cardiac Output Measurement Completed NCT01678950
49 Adding Malabsorption for Failed Gastric Bypass Completed NCT01040481
50 A Nutrition/Hygiene Education Program for the Prevention of Child Malnutrition in Rural Kenya Completed NCT01679535

Search NIH Clinical Center for Protein-Energy Malnutrition

Cochrane evidence based reviews: protein-energy malnutrition

Genetic Tests for Protein-Energy Malnutrition

Anatomical Context for Protein-Energy Malnutrition

MalaCards organs/tissues related to Protein-Energy Malnutrition:

39
Liver, Prostate, Brain, Bone, Thyroid, Kidney, Testes

Publications for Protein-Energy Malnutrition

Articles related to Protein-Energy Malnutrition:

(show top 50) (show all 533)
id Title Authors Year
1
Protein energy malnutrition alters mucosal IgA responses and reduces mucosal vaccine efficacy in mice. ( 28860040 )
2017
2
Genetic Engineering: A Possible Strategy for Protein-Energy Malnutrition Regulation. ( 28828714 )
2017
3
Honey can repairing damage of liver tissue due to protein energy malnutrition through induction of endogenous stem cells. ( 28717326 )
2017
4
An Adjuvanted A(H5N1) Subvirion Vaccine Elicits Virus-Specific Antibody Response and Improves Protection Against Lethal Influenza Viral Challenge in Mouse Model of Protein Energy Malnutrition. ( 28934453 )
2017
5
Protein energy malnutrition associates with different types of hearing impairments in toddlers: Anemia increases cochlear dysfunction. ( 27240492 )
2016
6
Protein-energy malnutrition in the rehabilitation setting: Evidence to improve identification. ( 26921933 )
2016
7
Serum hyaluronic acid predicts protein-energy malnutrition in chronic hepatitis C. ( 27311000 )
2016
8
Protein-energy malnutrition is frequent and precocious in children with cri du chat syndrome. ( 26872355 )
2016
9
Prognostic significance of low skeletal muscle mass compared with protein-energy malnutrition in liver cirrhosis. ( 27862791 )
2016
10
Does protein energy malnutrition affect the outcome in Tunisian cirrhotic patients? ( 27532543 )
2016
11
The Arid Melancholy-Netherton Syndrome With Protein Energy Malnutrition. ( 27190931 )
2016
12
Factors Associated With Protein-energy Malnutrition in Chronic Liver Disease: Analysis Using Indirect Calorimetry. ( 26765430 )
2016
13
Convergence of a diabetes mellitus, protein energy malnutrition, and TB epidemic: the neglected elderly population. ( 27456231 )
2016
14
Evaluation of dental age in protein energy malnutrition children. ( 26538919 )
2015
15
Protein Energy Malnutrition during Vaccination Has Limited Influence on Vaccine Efficacy but Abolishes Immunity if Administered during Mycobacterium tuberculosis Infection. ( 25754202 )
2015
16
Protein-energy malnutrition: a risk factor for various ailments. ( 24915388 )
2015
17
Protein-Energy Malnutrition Causes Deficits in Motor Function in Adult Male Rats. ( 26423735 )
2015
18
Seroprevalence rate of Poliovirus antibodies among the Healthy and Protein Energy Malnutrition children. ( 26101500 )
2015
19
Serum vitamin D status in children with protein-energy malnutrition admitted to a national referral hospital in Uganda. ( 26346815 )
2015
20
Protein-energy malnutrition at mid-adulthood does not imprint long-term metabolic consequences in male rats. ( 26133298 )
2015
21
Leucine Supplementation Improves Acquired Growth Hormone Resistance in Rats with Protein-Energy Malnutrition. ( 25909895 )
2015
22
Protein energy malnutrition in India: the plight of our under five children. ( 24791240 )
2014
23
Free radicals and antioxidant status in protein energy malnutrition. ( 24790610 )
2014
24
Protein energy malnutrition increases arginase activity in monocytes and macrophages. ( 25392710 )
2014
25
Determinants of protein-energy malnutrition in community dwelling older adults: A systematic review of observational studies. ( 25257179 )
2014
26
Protein-energy malnutrition developing after global brain ischemia induces an atypical acute-phase response and hinders expression of GAP-43. ( 25259609 )
2014
27
Maternal protein-energy malnutrition during early pregnancy in sheep impacts the fetal ornithine cycle to reduce fetal kidney microvascular development. ( 25077559 )
2014
28
Protein-energy Malnutrition in Goitrous Schoolchildren of Isfahan, Iran. ( 24932384 )
2014
29
Protein Energy-Malnutrition: Does the In Vitro Zinc Sulfate Supplementation Improve Chromosomal Damage Repair? ( 25262017 )
2014
30
Prevalence of protein-energy malnutrition in hospital patients over 75 years of age admitted for hip fracture. ( 24998085 )
2014
31
A narrative review of recent progress in understanding the relationship between tuberculosis and protein energy malnutrition. ( 23942176 )
2013
32
Acquired protein energy malnutrition in glutaric acidemia. ( 23330977 )
2013
33
Cystic fibrosis: from protein-energy malnutrition to obesity with dyslipidemia. ( 24800027 )
2013
34
Relation of oxidative stress, zinc and alkaline phosphatase in protein energy malnutrition. ( 23373727 )
2013
35
Hematologic and Bone Marrow Changes in Children with Protein-Energy Malnutrition. ( 23987917 )
2013
36
Protein-energy malnutrition induces an aberrant acute-phase response and modifies the circadian rhythm of core temperature. ( 23855272 )
2013
37
Methicillin-resistant Staphylococcus aureus carriage in infants with protein-energy malnutrition. ( 24502042 )
2013
38
A comparison of the full Mini Nutritional Assessment, short-form Mini Nutritional Assessment, and Subjective Global Assessment to predict the risk of protein-energy malnutrition in patients on peritoneal dialysis: a cross-sectional study. ( 23000089 )
2013
39
Effect of a probiotic fermented milk on the thymus in Balb/c mice under non-severe protein-energy malnutrition. ( 23286742 )
2013
40
Effect of early childhood protein-energy malnutrition on permanent dentition dental caries. ( 24255941 )
2013
41
Rutin (quercetin rutinoside) induced protein-energy malnutrition in chronic kidney disease, but quercetin acted beneficially. ( 23876017 )
2013
42
Missed opportunities in the diagnosis and management of protein energy malnutrition among children under 5 years in Wakiso district, Uganda. ( 25035810 )
2013
43
Protein energy malnutrition decreases immunity and increases susceptibility to influenza infection in mice. ( 22949306 )
2013
44
Porcine placenta mitigates protein-energy malnutrition-induced fatigue. ( 24035056 )
2013
45
Protein-energy malnutrition alters IgA responses to rotavirus vaccination and infection but does not impair vaccine efficacy in mice. ( 24200975 )
2013
46
Hepatoprotective and nephroprotective effects of Cnidoscolus aconitifolius in protein energy malnutrition induced liver and kidney damage. ( 24174819 )
2013
47
Protein-energy malnutrition during early gestation in sheep blunts fetal renal vascular and nephron development and compromises adult renal function. ( 22106177 )
2012
48
Practical dietary management of protein energy malnutrition in young children with cow's milk protein allergy. ( 22435534 )
2012
49
High burden of protein-energy malnutrition in Nigeria: beyond the health care setting. ( 23209994 )
2012
50
Under-five protein energy malnutrition admitted at the University of Nigeria Teaching Hospital, Enugu: a 10 year retrospective review. ( 22704641 )
2012

Variations for Protein-Energy Malnutrition

Expression for Protein-Energy Malnutrition

Search GEO for disease gene expression data for Protein-Energy Malnutrition.

Pathways for Protein-Energy Malnutrition

GO Terms for Protein-Energy Malnutrition

Cellular components related to Protein-Energy Malnutrition according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.61 ALB HP IGF1 IL6 LEP PIGR
2 extracellular space GO:0005615 9.32 ALB GPT HP IGF1 IL6 LEP

Biological processes related to Protein-Energy Malnutrition according to GeneCards Suite gene sharing:

(show all 18)
id Name GO ID Score Top Affiliating Genes
1 negative regulation of apoptotic process GO:0043066 9.87 ALB IGF1 IL6 LEP
2 platelet degranulation GO:0002576 9.71 ALB IGF1 TF
3 positive regulation of protein kinase B signaling GO:0051897 9.65 IL6 LEP TNF
4 positive regulation of MAPK cascade GO:0043410 9.63 IGF1 IL6 LEP
5 positive regulation of cytokine production GO:0001819 9.58 LEP TNF
6 positive regulation of JAK-STAT cascade GO:0046427 9.56 IL6 LEP
7 positive regulation of chemokine production GO:0032722 9.55 IL6 TNF
8 positive regulation of smooth muscle cell proliferation GO:0048661 9.54 IGF1 IL6 TNF
9 leukocyte tethering or rolling GO:0050901 9.52 LEP TNF
10 positive regulation of protein import into nucleus, translocation GO:0033160 9.51 IGF1 IL6
11 negative regulation of glucose import GO:0046325 9.49 LEP TNF
12 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.43 IGF1 IL6
13 epithelial cell proliferation involved in salivary gland morphogenesis GO:0060664 9.4 IL6 TNF
14 cellular protein metabolic process GO:0044267 9.35 ALB IGF1 IL6 TF TTR
15 retina homeostasis GO:0001895 9.33 ALB PIGR TF
16 bone mineralization involved in bone maturation GO:0035630 9.32 IGF1 LEP
17 positive regulation of STAT protein import into nucleus GO:2000366 9.26 IL6 LEP
18 negative regulation of lipid storage GO:0010888 8.8 IL6 LEP TNF

Molecular functions related to Protein-Energy Malnutrition according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 antioxidant activity GO:0016209 9.16 ALB HP
2 growth factor activity GO:0008083 9.13 IGF1 IL6 LEP
3 hormone activity GO:0005179 8.8 IGF1 LEP TTR

Sources for Protein-Energy Malnutrition

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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